BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0443.0013.p (514 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A7VHF1.1 A7VHF1_9CLOT Putative uncharacterized protein 295 8e-78 A5ZVU5.1 A5ZVU5_9FIRM Putative uncharacterized protein 291 1e-76 A8SQM8.1 A8SQM8_9FIRM Putative uncharacterized protein 281 1e-73 C4IIT9.1 C4IIT9_CLOBU Response regulator receiver protein 281 2e-73 C4Z3B2.1 C4Z3B2_9FIRM Two-component system, response regulator YesN 275 1e-71 >A7VHF1.1 A7VHF1_9CLOT Putative uncharacterized protein Length = 505 Score = 295 bits (755), Expect = 8e-78, Method: Compositional matrix adjust. Identities = 177/512 (34%), Positives = 285/512 (55%), Gaps = 22/512 (4%) Query: 7 MLTILIADDQREEREGIEFLIRELGFFLHIETAENGRKALEYLEKNPVDILFTDVRMPIM 66 M ILI DD++ ER GI FL+++L I A NG ALE LEK DIL TDV+MP M Sbjct: 1 MYKILIVDDEKIERNGIRFLLKKLNLEFEIAEAVNGVDALEKLEKEDFDILLTDVKMPFM 60 Query: 67 DGLQLTTEALTLQPKLKVILFSGFAEFEYAKTAISLGVSEYLLKPINVEAFRNTMQKVIA 126 DG++L + + KL+ ++FSG EF+YAK AI LGV +Y+LKP++ F+NT+ KV+ Sbjct: 61 DGIELIDHVVKEKKKLRTVIFSGCNEFDYAKKAIRLGVVDYILKPVDPNEFKNTLNKVVN 120 Query: 127 QLTDQEQEHIAAQIKLEYVKKHVLFNLVNGLGIPPSMKE---ISFELPDRYHGMFLLEFD 183 +L + + +E++ +H L+ L+NG + +E +S +L ++ M L+EF+ Sbjct: 121 ELEEAKASDELKNKSMEFLYEHALYMLLNGTDVTKLRQEYSGLSLDLG-KFKNMLLMEFN 179 Query: 184 KNFFENAGPEFEEFILSLLEDPVDYVNLNGCQSLLLFPGLPAVSSCSFRDLGAHLHDSIL 243 +FF G +F+E + Y+NLN Q +LF G + + I Sbjct: 180 HDFFGRRGVDFKENENLKSIGILQYLNLNQQQE-ILFLG----DEMNILRKANEIVKIIK 234 Query: 244 DKYKVHCYLAINDEFTMLQDLSAALIQLDQLMEYRFFSPDHFVFEVKKDVYFAN--DMLP 301 Y CY+AI+ + L +++ + +L+ LME +F+ P+ VF + N P Sbjct: 235 ADYDADCYIAISSDIGDLSEVADKMEELEVLMENKFYHPEIHVF-------YPNMEGETP 287 Query: 302 GL---SDYELLDHIRNNLKERDIFSLRANTDLLYQKYANQAQFSQLYVKYMFSSLYQEIM 358 G+ D + ++ ++K +D+ +LR + +KY ++ ++SQ+Y+K++FS+L ++I Sbjct: 288 GIIQFDDDTFMKQMKQDIKMKDVEALREHFQRFCEKYRHKTEYSQIYIKFLFSNLMKDIY 347 Query: 359 TYSAPISEMELSHGXXXXXXXXXXXXXXXXXXAGITLLDREYNSSXXXXLNRDIAAVKQY 418 E EL+ I L+ + + +R++ VKQY Sbjct: 348 GSIDETDEAELNKDIEKLYMATDFQVLTELVEEAIRRLETCF-AGKTQMAHREVELVKQY 406 Query: 419 IEDHYGEDLSLDLLAAKIHLSPHYLSSIFKKNTGCGLNKYIKNVRMNIAKDMLQQTHLKV 478 I +YG +L +D+LA +HL+P YLS++FKK TG L+K+IK RM AKDML+ + K+ Sbjct: 407 IYRNYGSELGIDMLADMVHLAPSYLSTVFKKETGQNLSKFIKAYRMEQAKDMLENSMTKI 466 Query: 479 SDICYSVGFQNVSYFCQNFRDFFGQTPEKFRQ 510 DI + G+ NVSYFC +FR+FFG +P+KFR+ Sbjct: 467 VDISVACGYPNVSYFCSSFREFFGVSPQKFRE 498 >A5ZVU5.1 A5ZVU5_9FIRM Putative uncharacterized protein Length = 509 Score = 291 bits (745), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 181/514 (35%), Positives = 290/514 (56%), Gaps = 24/514 (4%) Query: 7 MLTILIADDQREEREGIEFLI-RELGFFLHIETAENGRKALEYLEKNPVDILFTDVRMPI 65 M +LI DD++ EREG+++L+ RE G ++ A NG++AL+ + + ++ TD++MP Sbjct: 1 MTNVLIVDDEKIEREGLKYLLSREEGE-RNVFEASNGKQALQIIRSEDIQLVLTDIKMPH 59 Query: 66 MDGLQLTTEALTLQPKLKVILFSGFAEFEYAKTAISLGVSEYLLKPINVEAFRNTMQK-- 123 MDGL+L+ A P L++I+FSG+++F +A+ AI GV+EY+LKP+N E F +QK Sbjct: 60 MDGLELSRRAKEENPALQIIIFSGYSDFTFAQEAIRYGVTEYILKPVNPEDFHKVIQKAE 119 Query: 124 -VIAQLTDQEQEHIAAQIKLE--YVKKHVLFNLVNGLGIPPSMKEISFELPDRYHGMFLL 180 VI Q +E I + L+ +++ ++ + L M I+ E + +H LL Sbjct: 120 KVIEQRKKKESREIKEKNFLQQYFLQNYLYSGKLETLEKAKDM--INLEKWNGWHCGILL 177 Query: 181 EFDKNFFENAGPEFEEFILSLLEDPVDYVNLNGCQSLLLFPGLPAVSSCSFRDLGAHLHD 240 E D FF+ A EE I L Y+NLN QSLLLF + C ++ + HL++ Sbjct: 178 ESDVAFFDTAEETLEEEIQKELRRVCFYLNLNARQSLLLFQDV----YCDYQLVANHLYN 233 Query: 241 SILDKYKVHCYLAINDEFTMLQDLSAALIQLDQLMEYRFFSPDHFVFEVKKDVYFANDML 300 + KY+ YLA++ +F + L L QL+Q ME +F+ P+ VF + DV + + Sbjct: 234 FMKRKYRDSFYLAVSRKFEGCECLPEILEQLEQQMEEKFYHPEKHVFSNEDDVLKLS--V 291 Query: 301 PGLSDYELLDHIRNNLKERDIFSLRANTDLLYQKYANQAQFSQLYVKYMFSSLYQEIMTY 360 + D +++ I ++ +D LR + L +KY + ++S +Y+K++FS++ QE+ Sbjct: 292 GEVQDSQIMQMISEDITRKDTDQLRKHFACLKEKYHDNTKYSAMYIKFVFSNVIQELFQE 351 Query: 361 SAPISEMELSHGXXXXXXXXXXXXXXXXXXAGI----TLLDREYNSSXXXXLNRDIAAVK 416 + E L H I LDR +SS ++AAVK Sbjct: 352 NQFSGERRLEHEIERLYNCRNIMEILEVTEDNIKEYEAFLDRSMSSS-----RNEVAAVK 406 Query: 417 QYIEDHYGEDLSLDLLAAKIHLSPHYLSSIFKKNTGCGLNKYIKNVRMNIAKDMLQQTHL 476 YI HY EDL+L++LA K++LS YLS IFKK TG LN+YI+ RM AK++L T++ Sbjct: 407 NYIYQHYEEDLNLEMLAEKVYLSSGYLSFIFKKETGMNLNRYIRVFRMEKAKELLCSTNM 466 Query: 477 KVSDICYSVGFQNVSYFCQNFRDFFGQTPEKFRQ 510 KV+ + VGF NVSYFC++FR+++G +PE +R+ Sbjct: 467 KVAQVSERVGFANVSYFCRSFREYYGSSPESYRK 500 >A8SQM8.1 A8SQM8_9FIRM Putative uncharacterized protein Length = 523 Score = 281 bits (718), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 172/517 (33%), Positives = 292/517 (56%), Gaps = 26/517 (5%) Query: 4 AAGMLTILIADDQREEREGIEFLIRELGFFLHIETAENGRKALEYLEKNPVDILFTDVRM 63 + M ILI DD+R ER GI FL+++L I+ A NG ALE + + DIL TDV+M Sbjct: 16 SGEMYRILIVDDERIERNGIRFLLKKLNMEFDIDEAVNGLDALEKIRQEDYDILLTDVKM 75 Query: 64 PIMDGLQLTTEALTLQPKLKVILFSGFAEFEYAKTAISLGVSEYLLKPINVEAFRNTMQK 123 P MDG++L + + K++ ++FSG EF+YAK AI LGV +Y+LKP++ + F++T++K Sbjct: 76 PFMDGIELIDNVVNEKKKMRCVIFSGCNEFDYAKRAIRLGVVDYILKPVDPKEFKDTLEK 135 Query: 124 VIAQLTDQEQEHIAAQIKLEYVKKHVLFNLVNGLGIPPSMKE-----ISFELPDRYHGMF 178 V+ +L + +E++ +H L+ LVNG I +E ++F R+ + Sbjct: 136 VVDELEAAKASDELKSKSMEFLYEHALYMLVNGEDIESIRREYNGLNLNFA---RFKRIL 192 Query: 179 LLEFDKNFFENAGPEFE--EFILSLLEDPVDYVNLNGCQSLL-LFPGLPAVSSCSFRDLG 235 L+EF+ +FF +F+ E I++L Y+NLN Q L+ L AV + Sbjct: 193 LVEFNHDFFGRRDVDFKKNEKIMAL--GIQRYLNLNQQQELIFLGDETDAVYT------A 244 Query: 236 AHLHDSILDKYKVHCYLAINDEFTMLQDLSAALIQLDQLMEYRFFSPDHFVF--EVKKDV 293 L I Y C++A++ + +D+ + +LD+LM+ +F+ P+ VF ++ D Sbjct: 245 QELVKIIKSDYDEECFIAVSSDIEKPEDMKQKVDELDELMDNKFYHPEIKVFYPNMESD- 303 Query: 294 YFANDMLPGLSDYELLDHIRNNLKERDIFSLRANTDLLYQKYANQAQFSQLYVKYMFSSL 353 ++ M+ D L+ ++ ++K +D+ +LR + D +KY ++ + SQ+Y+K+++S+L Sbjct: 304 --SSGMIQ-FDDDTLMKQMKQDIKMKDVEALREHFDKFCEKYRHKNECSQIYIKFLYSNL 360 Query: 354 YQEIMTYSAPISEMELSHGXXXXXXXXXXXXXXXXXXAGITLLDREYNSSXXXXLNRDIA 413 ++I SE +L+ I L + ++++ Sbjct: 361 LKDIYGSIDGTSEADLNKDVEKMYMTTDFQSLTGLVEVAIDRLAACFEDKSQTG-HKEVE 419 Query: 414 AVKQYIEDHYGEDLSLDLLAAKIHLSPHYLSSIFKKNTGCGLNKYIKNVRMNIAKDMLQQ 473 VKQYI +YG +L +D+LA ++L+P YLS++FKK TG L+K+IK+ RM A+DML+ Sbjct: 420 MVKQYIYRNYGSELGIDMLADMVYLAPSYLSTVFKKETGQNLSKFIKSYRMERARDMLEN 479 Query: 474 THLKVSDICYSVGFQNVSYFCQNFRDFFGQTPEKFRQ 510 + K+ DI G+QNVSYFC +FR+F+G +P+KFR+ Sbjct: 480 SMAKIVDIGAMCGYQNVSYFCSSFREFYGVSPQKFRE 516 >C4IIT9.1 C4IIT9_CLOBU Response regulator receiver protein Length = 508 Score = 281 bits (718), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 167/515 (32%), Positives = 288/515 (55%), Gaps = 21/515 (4%) Query: 7 MLTILIADDQREEREGIEFLIRELGFFLHIETAENGRKALEYLEKNPVDILFTDVRMPIM 66 M+ ILI DD+ ER GI+FL++++ HI A NG ALEYL+ +DILFTD++MP M Sbjct: 1 MIKILIVDDEGIERRGIKFLLKQIKVDFHICEAANGMDALEYLKTQDIDILFTDIKMPFM 60 Query: 67 DGLQLTTEALTLQPKLKVILFSGFAEFEYAKTAISLGVSEYLLKPINVEAFRNTMQKVIA 126 DG+ L E K K+++FSG+ EFEYAK A +GV Y+LKP++ + F++T+ +++ Sbjct: 61 DGMDLIKEVKNNDIKCKIVIFSGYEEFEYAKFATKMGVINYILKPVDPDEFKSTIIRILN 120 Query: 127 QLTDQEQEHIAAQIKLEYVKKHVLFNLVNGLGIPPSMKEISF------ELPDRYHGMFLL 180 ++ D++ + + ++++H+L++LVNG P EI F Y M L+ Sbjct: 121 EIKDEKVKEEKNIRNMSFLREHILYSLVNGTS--PKELEIKFNDVIDLSFIKEYRRMILI 178 Query: 181 EFDKNFFENAGPEFEEFILSLLEDPVDYVNLNGCQSLLLFPGLPAVSSCSFRDL---GAH 237 EF+++FF + E+ I Y+NLN QSLL + + +RD+ Sbjct: 179 EFEEDFFGVKEYDIEKIIKDNTNIQFKYLNLNQRQSLLFINNIGS----EYRDIKEAAYS 234 Query: 238 LHDSILDKYKVHCYLAINDEFTMLQDLSAALIQLDQLMEYRFF-SPDHFVFEVKKDVYFA 296 ++++I C+++ + +D+ A +++ L+E RF+ + D +F D F Sbjct: 235 IYNTIRMNCMSECFVSAGKKIEKAEDILGAYGRIELLIEKRFYNNSDEHIF---IDDEFN 291 Query: 297 NDMLPGLSDYE-LLDHIRNNLKERDIFSLRANTDLLYQKYANQAQFSQLYVKYMFSSLYQ 355 ++ +D + +L I+ ++ +D SL+ N L Y N S +YVK++FS++ + Sbjct: 292 EKVISSKNDTDIILKKIKQDMSIKDTESLKDNFKKLCDLYENDNDISNMYVKFIFSNVLK 351 Query: 356 EIMTYSAPISEMELSHGXXXXXXXXXXXXXXXXXXAGITLLDREYNSSXXXXLNRDIAAV 415 ++ +SE I + E S ++++I + Sbjct: 352 DLYENLNEVSEKGFKEDINKIYKSSDFASVVRIINEYIVRFE-ESISDNPLLVHKEIETI 410 Query: 416 KQYIEDHYGEDLSLDLLAAKIHLSPHYLSSIFKKNTGCGLNKYIKNVRMNIAKDMLQQTH 475 K+YI ++Y +D+ +++LAA++ +P YLS IFKK TG L+K+IK+ RM AK+ML+ T+ Sbjct: 411 KKYIYENYDKDIGVEVLAAQVCFAPSYLSYIFKKETGQNLSKFIKSYRMIKAKEMLETTY 470 Query: 476 LKVSDICYSVGFQNVSYFCQNFRDFFGQTPEKFRQ 510 K+ ++ Y+VG++NVSYFCQ+FR++FG +P+KFR Sbjct: 471 EKIVNVSYAVGYRNVSYFCQSFREYFGVSPQKFRN 505 >C4Z3B2.1 C4Z3B2_9FIRM Two-component system, response regulator YesN Length = 514 Score = 275 bits (702), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 170/515 (33%), Positives = 281/515 (54%), Gaps = 19/515 (3%) Query: 7 MLTILIADDQREEREGIEFLIRELGFFLHIETAENGRKALEYL--EKNP----VDILFTD 60 M ILI DD++ ER GI L++ +G L + A NG++ALEYL +KN +DIL TD Sbjct: 1 MYNILIVDDEKIERSGIRMLLKRMGIELGVFEACNGKQALEYLTSDKNTGIGHIDILLTD 60 Query: 61 VRMPIMDGLQLTTEALTLQPKLKVILFSGFAEFEYAKTAISLGVSEYLLKPINVEAFRNT 120 V+MP MDG++L + LK I+FSG+ EFEYAK A+ LGV +Y+LKP++ F +T Sbjct: 61 VKMPFMDGIELIKNVMHNDISLKTIIFSGYNEFEYAKLAVKLGVKDYILKPVDPSEFSST 120 Query: 121 MQKVIAQLTDQEQEHIAAQIKLEYVKKHVLFNLVNGLGIPPSMKEISFELPDRYHGMFLL 180 + VI +L ++ ++ + ++K++ ++ L+N + F Y+ + L+ Sbjct: 121 ITGVITELDEEHKKDEDYNRQANFIKQYYMYTLLNSGDASGILDNGDFLAG--YNRLALI 178 Query: 181 EFDKNFFE--NAGPEFEEFILSLLEDPVDYVNLNGCQSLLLFPGLPAVSSCSF----RDL 234 EF+ +FF + G + + I L+ Y+NLN QS+++F + + ++ Sbjct: 179 EFNTDFFGKYDTGEDIFKEITGELD--YQYLNLNPLQSVIIFSDKSFTADGNIDKNIEEM 236 Query: 235 GAHLHDSILDKYKVHCYLAINDEFTMLQDLSAALIQLDQLMEYRFFSPDHFVFEVKKDVY 294 ++HD I K Y+A++ F +L + +D LM +F+ ++F ++ Sbjct: 237 FTNIHDYIYRKTGQFMYIAVSGLFNDYHELPQVMDAVDTLMNNKFYETGRYIF--SDNIS 294 Query: 295 FANDMLPGLSDYELLDHIRNNLKERDIFSLRANTDLLYQKYANQAQFSQLYVKYMFSSLY 354 +L + D L+ ++ ++K +DI LR + D L +KY Q+ FS +Y+K++FS+L Sbjct: 295 EDTPVLVQIDDDALMKQMKQDIKMKDITFLRIHFDALCKKYRGQSNFSHIYIKFVFSNLL 354 Query: 355 QEIMTYSAPISEMELSHGXXXXXXXXXXXXXXXXXXAGITLLDREYNSSXXXXLNRDIAA 414 ++ E E I LL++ + +R+I Sbjct: 355 KDFYDNIPGADEAEFGREIDRLYKSEDFSCIMDIVNNYIDLLEKSFGKEPATS-HREIET 413 Query: 415 VKQYIEDHYGEDLSLDLLAAKIHLSPHYLSSIFKKNTGCGLNKYIKNVRMNIAKDMLQQT 474 VK YI +HYGE++ LA ++L+P YLSS+FKK TG L+KYIK RM AK++L T Sbjct: 414 VKNYIHNHYGEEIGAQQLADMVYLAPSYLSSLFKKETGQNLSKYIKQYRMEKAKELLTGT 473 Query: 475 HLKVSDICYSVGFQNVSYFCQNFRDFFGQTPEKFR 509 ++K+ +I VG+ NVSYF Q+FR++FG +P+KFR Sbjct: 474 NMKIVNISEQVGYPNVSYFVQSFREYFGISPQKFR 508 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.323 0.139 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,805,340,278 Number of extensions: 113710081 Number of successful extensions: 351713 Number of sequences better than 1.0e-05: 9779 Number of HSP's gapped: 364798 Number of HSP's successfully gapped: 10415 Length of query: 514 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 374 Effective length of database: 1,741,754,103 Effective search space: 651416034522 Effective search space used: 651416034522 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 134 (56.2 bits)