BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0443.0007.p (197 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K570.1 B3K570_9BACI GTP cyclohydrolase I EC=3.5.4.16 352 1e-95 B1D8S4.1 B1D8S4_9BACL GTP cyclohydrolase I EC=3.5.4.16 333 4e-90 B4AKI4.1 B4AKI4_BACPU GTP cyclohydrolase I EC=3.5.4.16 252 1e-65 A8FEL2.1 GCH1_BACP2 GTP cyclohydrolase 1 EC=3.5.4.16 252 1e-65 Q65I21.1 Q65I21_BACLD MtrA 251 2e-65 >B3K570.1 B3K570_9BACI GTP cyclohydrolase I EC=3.5.4.16 Length = 197 Score = 352 bits (902), Expect = 1e-95, Method: Compositional matrix adjust. Identities = 165/197 (83%), Positives = 182/197 (92%) Query: 1 MGGVKDYMNGKVAANREQIEYHVEKILQLIGEDPGREGLLETPARVTRMYEEIFGGYSID 60 M GVKDY+N KV NREQIEYHVE+IL+LIGEDP REGLLETPARVTRMYEEIF GY +D Sbjct: 1 MAGVKDYVNHKVGQNREQIEYHVEQILKLIGEDPKREGLLETPARVTRMYEEIFAGYEVD 60 Query: 61 PREALGVTFDESHEELVIVKDIVYYSQCEHHMAPFFGKVHIGYIPSGRIAGLSKLARLVE 120 P++ LGVTFDE+HEELVIVKDIVYYSQCEHHMAPFFGKVHIGY+PSG+IAGLSKLARLVE Sbjct: 61 PKDVLGVTFDENHEELVIVKDIVYYSQCEHHMAPFFGKVHIGYVPSGKIAGLSKLARLVE 120 Query: 121 AVSRRLQVQERITAQIADIMTEVLNPHGVMVVVEGEHLCMCARGVKKPGSKTVTMAARGT 180 AV+RRLQVQERIT+QIADIM E L P+GVMVVVEGEHLCMCARGVKKPGSKTVT A RGT Sbjct: 121 AVTRRLQVQERITSQIADIMVEALQPNGVMVVVEGEHLCMCARGVKKPGSKTVTSAVRGT 180 Query: 181 FREDAAARAEFLALIKE 197 F+ D+A R+EFL+LIK+ Sbjct: 181 FQSDSAQRSEFLSLIKD 197 >B1D8S4.1 B1D8S4_9BACL GTP cyclohydrolase I EC=3.5.4.16 Length = 196 Score = 333 bits (855), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 159/197 (80%), Positives = 176/197 (89%), Gaps = 1/197 (0%) Query: 1 MGGVKDYMNGKVAANREQIEYHVEKILQLIGEDPGREGLLETPARVTRMYEEIFGGYSID 60 M G+KDY+N V+ NR+QIE+H+++IL+L+GED REGLLETPARVTRMYEEIF GY +D Sbjct: 1 MAGMKDYVNSAVSRNRDQIEHHIKEILKLVGEDVEREGLLETPARVTRMYEEIFAGYEVD 60 Query: 61 PREALGVTFDESHEELVIVKDIVYYSQCEHHMAPFFGKVHIGYIPSGRIAGLSKLARLVE 120 PRE LGVTFDE HEELVIVKDIVYYSQCEHHMAPFFGK HIGYIPSG+IAGLSKLARLVE Sbjct: 61 PREVLGVTFDERHEELVIVKDIVYYSQCEHHMAPFFGKAHIGYIPSGKIAGLSKLARLVE 120 Query: 121 AVSRRLQVQERITAQIADIMTEVLNPHGVMVVVEGEHLCMCARGVKKPGSKTVTMAARGT 180 AVSRRLQVQERIT QIADIM EVL P GVMVVVEGEHLCMCARGVKKPGSKTVT A RG Sbjct: 121 AVSRRLQVQERITTQIADIMQEVLKPQGVMVVVEGEHLCMCARGVKKPGSKTVTSAVRGV 180 Query: 181 FREDAAARAEFLALIKE 197 F D+A R+EFL+L+K+ Sbjct: 181 F-SDSALRSEFLSLLKQ 196 >B4AKI4.1 B4AKI4_BACPU GTP cyclohydrolase I EC=3.5.4.16 Length = 189 Score = 252 bits (644), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 118/183 (64%), Positives = 142/183 (77%), Gaps = 1/183 (0%) Query: 15 NREQIEYHVEKILQLIGEDPGREGLLETPARVTRMYEEIFGGYSIDPREALGVTFDESHE 74 N+E IE+ V IL+ IGEDP REGLL+TP RV +MYEE+F G + DP+E F E HE Sbjct: 5 NKELIEHAVRDILKAIGEDPDREGLLDTPKRVAKMYEEVFSGLNEDPKEHFKTIFGEDHE 64 Query: 75 ELVIVKDIVYYSQCEHHMAPFFGKVHIGYIP-SGRIAGLSKLARLVEAVSRRLQVQERIT 133 ELV+VKDI ++S CEHH+ PF+GK H+ YIP G++ GLSKLAR VEAV++R Q+QERIT Sbjct: 65 ELVLVKDIAFHSMCEHHLVPFYGKAHVAYIPRGGKVTGLSKLARAVEAVAKRPQLQERIT 124 Query: 134 AQIADIMTEVLNPHGVMVVVEGEHLCMCARGVKKPGSKTVTMAARGTFREDAAARAEFLA 193 + IAD M E LNPHGVM+VVE EH+CM RGVKKPG+KTVT A RGTF DAAARAE L+ Sbjct: 125 STIADSMVETLNPHGVMIVVEAEHMCMTMRGVKKPGAKTVTSAVRGTFANDAAARAEVLS 184 Query: 194 LIK 196 IK Sbjct: 185 FIK 187 >A8FEL2.1 GCH1_BACP2 GTP cyclohydrolase 1 EC=3.5.4.16 Length = 189 Score = 252 bits (644), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 118/183 (64%), Positives = 142/183 (77%), Gaps = 1/183 (0%) Query: 15 NREQIEYHVEKILQLIGEDPGREGLLETPARVTRMYEEIFGGYSIDPREALGVTFDESHE 74 N+E IE+ V IL+ IGEDP REGLL+TP RV +MYEE+F G + DP+E F E HE Sbjct: 5 NKELIEHAVRDILKAIGEDPDREGLLDTPKRVAKMYEEVFSGLNEDPKEHFKTIFGEDHE 64 Query: 75 ELVIVKDIVYYSQCEHHMAPFFGKVHIGYIP-SGRIAGLSKLARLVEAVSRRLQVQERIT 133 ELV+VKDI ++S CEHH+ PF+GK H+ YIP G++ GLSKLAR VEAV++R Q+QERIT Sbjct: 65 ELVLVKDIAFHSMCEHHLVPFYGKAHVAYIPRGGKVTGLSKLARAVEAVAKRPQLQERIT 124 Query: 134 AQIADIMTEVLNPHGVMVVVEGEHLCMCARGVKKPGSKTVTMAARGTFREDAAARAEFLA 193 + IAD M E LNPHGVM+VVE EH+CM RGVKKPG+KTVT A RGTF DAAARAE L+ Sbjct: 125 STIADSMVETLNPHGVMIVVEAEHMCMTMRGVKKPGAKTVTSAVRGTFANDAAARAEVLS 184 Query: 194 LIK 196 IK Sbjct: 185 FIK 187 >Q65I21.1 Q65I21_BACLD MtrA Length = 189 Score = 251 bits (642), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 118/183 (64%), Positives = 142/183 (77%), Gaps = 1/183 (0%) Query: 15 NREQIEYHVEKILQLIGEDPGREGLLETPARVTRMYEEIFGGYSIDPREALGVTFDESHE 74 N++QIE V +IL+ IGEDP REGLL+TP RV +MY E+F G + DP+E F E HE Sbjct: 5 NKDQIEQAVRQILEAIGEDPNREGLLDTPKRVAKMYAEVFAGLNEDPKEHFKTIFGEDHE 64 Query: 75 ELVIVKDIVYYSQCEHHMAPFFGKVHIGYIPSG-RIAGLSKLARLVEAVSRRLQVQERIT 133 ELV+VKDI +YS CEHH+ PF+GK H+ YIP G ++ GLSKLAR VEAV++R Q+QERIT Sbjct: 65 ELVLVKDIPFYSMCEHHLVPFYGKAHVAYIPKGGKVTGLSKLARAVEAVAKRPQLQERIT 124 Query: 134 AQIADIMTEVLNPHGVMVVVEGEHLCMCARGVKKPGSKTVTMAARGTFREDAAARAEFLA 193 + IAD + E L PHGVMVVVE EH+CM RGVKKPGSKTVT A RGTFR+D AAR+E L Sbjct: 125 STIADSIVETLTPHGVMVVVEAEHMCMTMRGVKKPGSKTVTSAVRGTFRQDVAARSEVLE 184 Query: 194 LIK 196 LIK Sbjct: 185 LIK 187 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.137 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,140,616,298 Number of extensions: 44817841 Number of successful extensions: 108895 Number of sequences better than 1.0e-05: 1574 Number of HSP's gapped: 107335 Number of HSP's successfully gapped: 1598 Length of query: 197 Length of database: 3,060,696,203 Length adjustment: 129 Effective length of query: 68 Effective length of database: 1,845,385,268 Effective search space: 125486198224 Effective search space used: 125486198224 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 127 (53.5 bits)