BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0442.0007.p (748 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KA79.1 B3KA79_9BACI Phosphoribosylformylglycinamidine synthase... 1300 0.0 B1D8Y5.1 B1D8Y5_9BACL Phosphoribosylformylglycinamidine synthase... 1228 0.0 C0ZKC6.1 C0ZKC6_BREBN Phosphoribosylformylglycinamidine synthase... 1056 0.0 Q65MS8.1 PURL_BACLD Phosphoribosylformylglycinamidine synthase 2... 956 0.0 B4BRE0.1 B4BRE0_9BACI Phosphoribosylformylglycinamidine synthase... 939 0.0 >B3KA79.1 B3KA79_9BACI Phosphoribosylformylglycinamidine synthase II EC=6.3.5.3 Length = 747 Score = 1300 bits (3364), Expect = 0.0, Method: Compositional matrix adjust. Identities = 627/748 (83%), Positives = 673/748 (89%), Gaps = 1/748 (0%) Query: 1 MTQQVSAKEPTAEQIAEQKIYNQFGVSDSEYELITSFMGRKPNYTEIGVFSVMWSEHCAY 60 M QQ S KEPTAEQIAE +IY Q GVSDSEYELI SFMGRKPNYTEIGVFSVMWSEHCAY Sbjct: 1 MAQQTSVKEPTAEQIAEHQIYKQMGVSDSEYELICSFMGRKPNYTEIGVFSVMWSEHCAY 60 Query: 61 KNSKPLLGRFPTSGPRVLMGPGEGAGIVDIGDNQAVVFKIESHNHPSAVEPYQGAATGVG 120 KNSKPLL FPTSGPRVLMGPGEGAGIVDIGDNQAVVFKIESHNHPSAVEPYQGAATGVG Sbjct: 61 KNSKPLLRGFPTSGPRVLMGPGEGAGIVDIGDNQAVVFKIESHNHPSAVEPYQGAATGVG 120 Query: 121 GIIRDIFSMGARPVALMNSLRFGKLESDRVKYLFEHVVSGIAGYGNCIGIPTVGGEIMFD 180 GIIRDIFSMGARPVA++NSLRFGKLESDRVKYLFEHVVSGIAGYGNCIGIPTVGGE++FD Sbjct: 121 GIIRDIFSMGARPVAILNSLRFGKLESDRVKYLFEHVVSGIAGYGNCIGIPTVGGEVVFD 180 Query: 181 NSYDGNPLVNAMCVGLIDHDKIQRGVAKGVGNPVFYVGPPTGRDGIHGATFASVELSEES 240 SY+GNPLVNAMCVG+IDHDKIQRGVAKGVGNPVFYVGPPTGRDGIHGATFASVEL+EES Sbjct: 181 ESYEGNPLVNAMCVGVIDHDKIQRGVAKGVGNPVFYVGPPTGRDGIHGATFASVELTEES 240 Query: 241 EAKKTAVQVGDPFMEKLVMESCLELIDSGIVLGIQDMGAAGLTCSSAEMASKAGNGLELY 300 EA +TAVQVGDPFMEKLVMESCLELIDSGIVLGIQDMGAAGLTCSSAEMASKAGNGLELY Sbjct: 241 EANRTAVQVGDPFMEKLVMESCLELIDSGIVLGIQDMGAAGLTCSSAEMASKAGNGLELY 300 Query: 301 LDQVPQREDGMTPYEMMLSESQERMLFVVEPKDEAQAQEIFDRWGVICRKVGKVTDDGRL 360 LDQVPQRE+GMTPYEMMLSESQERMLFVVEPK EAQA+EIF+RWGVIC KVGKVTDDGRL Sbjct: 301 LDQVPQREEGMTPYEMMLSESQERMLFVVEPKHEAQAREIFERWGVICAKVGKVTDDGRL 360 Query: 361 KLFHHGEVVGDMPVKALVDECPIYKKPSAVPAYYEENASVDTLRYAEVKDLGGALHTVLA 420 KL HHGEVVGDMPVKALVDECPIY KPS PAYY+E A+VDTLRY EVKDLGGAL VLA Sbjct: 361 KLIHHGEVVGDMPVKALVDECPIYNKPSQEPAYYQEQAAVDTLRYEEVKDLGGALKKVLA 420 Query: 421 SPTVASKAWVYNQYDYMVRTSTAVRPGSDAAVVTIHGTRKGLAMTTDCNGRYVYLDPEVG 480 SP++ASKAWVYNQYDYMVRTSTAVRPGSDAAVVT+HGTRK LAMTTDCNGRYVYLDPE+G Sbjct: 421 SPSLASKAWVYNQYDYMVRTSTAVRPGSDAAVVTVHGTRKALAMTTDCNGRYVYLDPELG 480 Query: 481 GRIAVSEAARNIVCSGAKPLAITDNLNFGSPEKPEIFWQMERAVDGMAEACRVLDTPVIG 540 GRIAVSEAARNIVCSGA+PLAITDNLNFGSPEKPEIFWQME+AVDGMAEACR L+TPVIG Sbjct: 481 GRIAVSEAARNIVCSGAEPLAITDNLNFGSPEKPEIFWQMEKAVDGMAEACRELETPVIG 540 Query: 541 GNVSLYNENASGAIYPTPVVGMVGLVEDTDHITTQAFKQEGDAILLLGVTKAELGGSEFQ 600 GNVSLYNENA GAIYPTPVVGMVGL+ DTDHITTQAFK EGDAI +LG T AELGGSEFQ Sbjct: 541 GNVSLYNENAKGAIYPTPVVGMVGLIHDTDHITTQAFKAEGDAIYVLGDTLAELGGSEFQ 600 Query: 601 YAVHGLTEGRPPELDLATEQKLLDAVLAAIRSGLVRSAHDXXXXXXXXXXXXXCISGSIG 660 +HG++EGRPPEL+L E+KLL VL AI+SGLV+SAHD CISG IG Sbjct: 601 AIIHGVSEGRPPELNLDIEKKLLGGVLKAIQSGLVQSAHDVSEGGLAAALAESCISGGIG 660 Query: 661 ANVEWSAGGLRRDVALFSESQSRIVLTAAPGRAEELRAAVAAYGVPAEIIGTVGGDRLRV 720 A+V+W A LR DVALFSESQSRIVL+A+P L + GVP +G VGG++L + Sbjct: 661 ASVKW-ATDLRNDVALFSESQSRIVLSASPDHKNALEKLLQEAGVPFTALGVVGGNKLSI 719 Query: 721 SLDGEAVLDEAVAALKTTWEDAIPCLMK 748 +++G + L+E+V ALK+ WEDAIPCLM Sbjct: 720 NINGASALEESVEALKSVWEDAIPCLMN 747 >B1D8Y5.1 B1D8Y5_9BACL Phosphoribosylformylglycinamidine synthase II EC=6.3.5.3 Length = 747 Score = 1228 bits (3176), Expect = 0.0, Method: Compositional matrix adjust. Identities = 592/748 (79%), Positives = 649/748 (86%), Gaps = 1/748 (0%) Query: 1 MTQQVSAKEPTAEQIAEQKIYNQFGVSDSEYELITSFMGRKPNYTEIGVFSVMWSEHCAY 60 M QQ++AKEPTAEQI EQKIY QFGVSD E+ELI F+GR PNYTEIGVFSVMWSEHCAY Sbjct: 1 MAQQLTAKEPTAEQIVEQKIYQQFGVSDYEFELICGFLGRTPNYTEIGVFSVMWSEHCAY 60 Query: 61 KNSKPLLGRFPTSGPRVLMGPGEGAGIVDIGDNQAVVFKIESHNHPSAVEPYQGAATGVG 120 KNSKP+L +FP +GPRVLMGPGEGAGIVDIGDNQAVVFKIESHNHPSAVEPYQGAATGVG Sbjct: 61 KNSKPILKKFPITGPRVLMGPGEGAGIVDIGDNQAVVFKIESHNHPSAVEPYQGAATGVG 120 Query: 121 GIIRDIFSMGARPVALMNSLRFGKLESDRVKYLFEHVVSGIAGYGNCIGIPTVGGEIMFD 180 GIIRDIFSMGARPVAL+NSLRFGKLE+DRVKYLFE+VVSGIAGYGNCIGIPT+ GE+MFD Sbjct: 121 GIIRDIFSMGARPVALLNSLRFGKLENDRVKYLFENVVSGIAGYGNCIGIPTIAGEVMFD 180 Query: 181 NSYDGNPLVNAMCVGLIDHDKIQRGVAKGVGNPVFYVGPPTGRDGIHGATFASVELSEES 240 SY+GNPLVNAMCVGLIDHDKIQRGVAKGVGNPVFYVGP TGRDGIHGATFASVEL+EES Sbjct: 181 ESYEGNPLVNAMCVGLIDHDKIQRGVAKGVGNPVFYVGPATGRDGIHGATFASVELTEES 240 Query: 241 EAKKTAVQVGDPFMEKLVMESCLELIDSGIVLGIQDMGAAGLTCSSAEMASKAGNGLELY 300 E K+TAVQVGDPFMEKLVMES LELI+SGIVLGIQDMGAAGLTCSSAEMASKAGNGLELY Sbjct: 241 EEKRTAVQVGDPFMEKLVMESTLELINSGIVLGIQDMGAAGLTCSSAEMASKAGNGLELY 300 Query: 301 LDQVPQREDGMTPYEMMLSESQERMLFVVEPKDEAQAQEIFDRWGVICRKVGKVTDDGRL 360 LD+VPQRE GMTPYEMMLSESQERMLFVVEP+ EAQAQEIFDRWGVIC+KVGKVTDDGRL Sbjct: 301 LDEVPQRETGMTPYEMMLSESQERMLFVVEPQHEAQAQEIFDRWGVICKKVGKVTDDGRL 360 Query: 361 KLFHHGEVVGDMPVKALVDECPIYKKPSAVPAYYEENASVDTLRYAEVKDLGGALHTVLA 420 +LFH GE V DMPVKALVDECP+Y+KPS PAYY NA++DT + EV DL GAL VLA Sbjct: 361 RLFHQGEQVADMPVKALVDECPVYEKPSQEPAYYRTNATLDTAAFTEVTDLTGALEKVLA 420 Query: 421 SPTVASKAWVYNQYDYMVRTSTAVRPGSDAAVVTIHGTRKGLAMTTDCNGRYVYLDPEVG 480 SPTVASK WVYNQYDYMVRTSTAV+PGSDAAVVTI GTRKGLAMTTDCNGRYVYLDPEVG Sbjct: 421 SPTVASKEWVYNQYDYMVRTSTAVQPGSDAAVVTIRGTRKGLAMTTDCNGRYVYLDPEVG 480 Query: 481 GRIAVSEAARNIVCSGAKPLAITDNLNFGSPEKPEIFWQMERAVDGMAEACRVLDTPVIG 540 GRIAV+EAARNIVCSGA+PLAITDNLNFGSPEKPE+FWQ+E+A DGM+EACRVLDTPVIG Sbjct: 481 GRIAVAEAARNIVCSGAEPLAITDNLNFGSPEKPEVFWQIEKAADGMSEACRVLDTPVIG 540 Query: 541 GNVSLYNENASGAIYPTPVVGMVGLVEDTDHITTQAFKQEGDAILLLGVTKAELGGSEFQ 600 GNVSLYNENA GAIYPTPV+GMVGLV D DHITTQ FK+EGD I+L+G TKAE GGSE Sbjct: 541 GNVSLYNENAKGAIYPTPVIGMVGLVHDVDHITTQGFKKEGDVIILVGDTKAEFGGSELL 600 Query: 601 YAVHGLTEGRPPELDLATEQKLLDAVLAAIRSGLVRSAHDXXXXXXXXXXXXXCISGSIG 660 Y ++G EGRPP +DLATE+ +L AVL AI+ GLV SAHD ISG IG Sbjct: 601 YVLNGAAEGRPPAIDLATEKNMLGAVLTAIQGGLVASAHDLSEGGLAVALAESAISGGIG 660 Query: 661 ANVEWSAGGLRRDVALFSESQSRIVLTAAPGRAEELRAAVAAYGVPAEIIGTVGGDRLRV 720 A V + LR D LFSESQSRI+L+A P +A L+A + GV IGTV G L + Sbjct: 661 AEVNVTT-DLRPDHMLFSESQSRILLSATPEKAAALQAHLTEQGVVNAAIGTVKGSSLTI 719 Query: 721 SLDGEAVLDEAVAALKTTWEDAIPCLMK 748 +++G++ + V L+ W+DAIPCLMK Sbjct: 720 NVNGKSGVHAPVQQLEKVWKDAIPCLMK 747 >C0ZKC6.1 C0ZKC6_BREBN Phosphoribosylformylglycinamidine synthase II EC=6.3.5.3 Length = 747 Score = 1056 bits (2730), Expect = 0.0, Method: Compositional matrix adjust. Identities = 504/745 (67%), Positives = 602/745 (80%), Gaps = 2/745 (0%) Query: 4 QVSAKEPTAEQIAEQKIYNQFGVSDSEYELITSFMGRKPNYTEIGVFSVMWSEHCAYKNS 63 Q++ KEPTAEQIA+QK+Y + G++D EY+ + +GRKPN+TE G++SVMWSEHC+YKNS Sbjct: 3 QLTHKEPTAEQIADQKLYKEIGLTDEEYQRVVEILGRKPNWTETGLYSVMWSEHCSYKNS 62 Query: 64 KPLLGRFPTSGPRVLMGPGEGAGIVDIGDNQAVVFKIESHNHPSAVEPYQGAATGVGGII 123 KP+L RFPT GPRVL GPGEGAGIVDIGDNQAVVFKIESHNHPSA+EPYQGAATGVGGII Sbjct: 63 KPVLRRFPTKGPRVLQGPGEGAGIVDIGDNQAVVFKIESHNHPSAIEPYQGAATGVGGII 122 Query: 124 RDIFSMGARPVALMNSLRFGKLESDRVKYLFEHVVSGIAGYGNCIGIPTVGGEIMFDNSY 183 RD+FSMGARP+AL+NSLRFG+L+S RVKYLFE+VV+GIAGYGNCIGIPTVGGE+ FD +Y Sbjct: 123 RDVFSMGARPIALLNSLRFGELKSPRVKYLFENVVAGIAGYGNCIGIPTVGGEVNFDPTY 182 Query: 184 DGNPLVNAMCVGLIDHDKIQRGVAKGVGNPVFYVGPPTGRDGIHGATFASVELSEESEAK 243 +GNPLVNAMCVGLIDH+KIQ+GVA G+GNPV YVG TGRDGIHGATFAS EL+EESE K Sbjct: 183 EGNPLVNAMCVGLIDHEKIQKGVASGIGNPVIYVGASTGRDGIHGATFASEELTEESEKK 242 Query: 244 KTAVQVGDPFMEKLVMESCLELIDSGIVLGIQDMGAAGLTCSSAEMASKAGNGLELYLDQ 303 + AVQVGDPFMEKL++E+CLELID+GIV+GIQDMGAAGLT SS+EMASKAGNG+E+ LD Sbjct: 243 RPAVQVGDPFMEKLLLEACLELIDTGIVVGIQDMGAAGLTSSSSEMASKAGNGIEMNLDL 302 Query: 304 VPQREDGMTPYEMMLSESQERMLFVVEPKDEAQAQEIFDRWGVICRKVGKVTDDGRLKLF 363 VPQRE GM+ YEMMLSESQERML VVE EA+A IFD+WG+ VGKVT+D +L+L Sbjct: 303 VPQREAGMSAYEMMLSESQERMLVVVEKGKEAEAIAIFDKWGLASAVVGKVTEDSKLRLL 362 Query: 364 HHGEVVGDMPVKALVDECPIYKKPSAVPAYYEENASVDTL-RYAEVKDLGGALHTVLASP 422 H GEVV ++PV +L ++ P+Y +PSAVPAYYE NA+VD L E KDL G L ++LA P Sbjct: 363 HQGEVVAEVPVDSLANDAPVYHRPSAVPAYYEANANVDVLAAIQEPKDLNGTLKSLLAQP 422 Query: 423 TVASKAWVYNQYDYMVRTSTAVRPGSDAAVVTIHGTRKGLAMTTDCNGRYVYLDPEVGGR 482 TVA+KAWVY QYD++VR +TAV+PGSDAAVV + GTRK LAM+TDCNGRYVYLDP+VGG Sbjct: 423 TVANKAWVYEQYDHIVRANTAVKPGSDAAVVMVRGTRKALAMSTDCNGRYVYLDPKVGGA 482 Query: 483 IAVSEAARNIVCSGAKPLAITDNLNFGSPEKPEIFWQMERAVDGMAEACRVLDTPVIGGN 542 IAV+E+ARN+VCSGA+PLAITD LNFGSPEKPE+FWQ E++ +GM+EAC LD PVIGGN Sbjct: 483 IAVAESARNVVCSGAEPLAITDCLNFGSPEKPEVFWQFEKSCEGMSEACVALDAPVIGGN 542 Query: 543 VSLYNENASGAIYPTPVVGMVGLVEDTDHITTQAFKQEGDAILLLGVTKAELGGSEFQYA 602 VS YNE + AIYPTP VGMVGL+ D DHITTQ FK EGDAI+LLG T AELGGSE+Q Sbjct: 543 VSFYNERSGDAIYPTPTVGMVGLITDVDHITTQDFKNEGDAIILLGETFAELGGSEYQKM 602 Query: 603 VHGLTEGRPPELDLATEQKLLDAVLAAIRSGLVRSAHDXXXXXXXXXXXXXCISGSIGAN 662 G GRPP++DL E + VL AIR GLV SAHD C +GA Sbjct: 603 ATGSISGRPPQIDLTKEAAVQKLVLTAIRQGLVNSAHDLSEGGLGVALAESCFGKGVGAQ 662 Query: 663 VEWSAGGLRRDVALFSESQSRIVLTAAPGRAEELRAAVAAYGVPAEIIGTVGGDRLRVSL 722 V ++ +R D LFSESQSRI+L+A+ +A + A GVPAE IGTVGGD L V++ Sbjct: 663 VTLTS-EMRIDALLFSESQSRILLSASGEQAAAILALAGELGVPAENIGTVGGDHLVVNV 721 Query: 723 DGEAVLDEAVAALKTTWEDAIPCLM 747 +G ++ + +K W+DAIPCL+ Sbjct: 722 NGTEAINASTQEVKAAWKDAIPCLI 746 >Q65MS8.1 PURL_BACLD Phosphoribosylformylglycinamidine synthase 2 EC=6.3.5.3 Length = 742 Score = 956 bits (2472), Expect = 0.0, Method: Compositional matrix adjust. Identities = 467/743 (62%), Positives = 565/743 (76%), Gaps = 12/743 (1%) Query: 9 EPTAEQIAEQKIYNQFGVSDSEYELITSFMGRKPNYTEIGVFSVMWSEHCAYKNSKPLLG 68 EP+ EQI E+K+Y Q GVSD E+ +I S +GR PNYTEIG+FSVMWSEHC+YKNSKP+L Sbjct: 6 EPSQEQIKEEKLYQQMGVSDDEFAMIESILGRLPNYTEIGIFSVMWSEHCSYKNSKPILK 65 Query: 69 RFPTSGPRVLMGPGEGAGIVDIGDNQAVVFKIESHNHPSAVEPYQGAATGVGGIIRDIFS 128 +FPT G RVL GPGEGAGIVDIGDNQAVVFKIESHNHPSA+EPYQGAATGVGGIIRD+FS Sbjct: 66 KFPTKGERVLQGPGEGAGIVDIGDNQAVVFKIESHNHPSAIEPYQGAATGVGGIIRDVFS 125 Query: 129 MGARPVALMNSLRFGKLESDRVKYLFEHVVSGIAGYGNCIGIPTVGGEIMFDNSYDGNPL 188 MGARP+A++NSLRFG+L S RVKYLFE VV+GIAGYGNCIGIPTVGGE+ FD Y+GNPL Sbjct: 126 MGARPIAVLNSLRFGELTSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDGCYEGNPL 185 Query: 189 VNAMCVGLIDHDKIQRGVAKGVGNPVFYVGPPTGRDGIHGATFASVELSEESEAKKTAVQ 248 VNAMCVGLI+H+ I++G AKGVGN V YVG TGRDGIHGATFAS E+S++SE K++AVQ Sbjct: 186 VNAMCVGLINHEDIKKGQAKGVGNTVMYVGAKTGRDGIHGATFASEEMSDQSEEKRSAVQ 245 Query: 249 VGDPFMEKLVMESCLELIDSGIVLGIQDMGAAGLTCSSAEMASKAGNGLELYLDQVPQRE 308 VGDPFMEKL++E+CLE+I S ++GIQDMGAAGLT SSAEMASKAG+G+E+ LD +PQRE Sbjct: 246 VGDPFMEKLLLEACLEVIKSDALVGIQDMGAAGLTSSSAEMASKAGSGIEMNLDLIPQRE 305 Query: 309 DGMTPYEMMLSESQERMLFVVEPKDEAQAQEIFDRWGVICRKVGKVTDDGRLKLFHHGEV 368 GMTPYEMMLSESQERML V+E E + +IFD++ + VG VTDD L+LFH+GE+ Sbjct: 306 TGMTPYEMMLSESQERMLLVIERGREQEIIDIFDKYDLEAVAVGHVTDDKMLRLFHNGEM 365 Query: 369 VGDMPVKALVDECPIYKKPSAVPAYYEENASVDTLRYAEVKDLGGALHTVLASPTVASKA 428 V ++PV AL +E P+Y KPS VP YY+E D + +V+D L +L PT+ASK Sbjct: 366 VAELPVDALAEEAPVYHKPSKVPDYYKEFLETD-VPAPKVEDAKETLLELLKQPTIASKE 424 Query: 429 WVYNQYDYMVRTSTAVRPGSDAAVVTIHGTRKGLAMTTDCNGRYVYLDPEVGGRIAVSEA 488 WVY+QYDYMVRT+T V PGSDAAV+ I GT+K LAMTTDCN RY+YLDPE GG+IAV+EA Sbjct: 425 WVYDQYDYMVRTNTVVAPGSDAAVLRIRGTKKALAMTTDCNARYLYLDPETGGKIAVAEA 484 Query: 489 ARNIVCSGAKPLAITDNLNFGSPEKPEIFWQMERAVDGMAEACRVLDTPVIGGNVSLYNE 548 ARNIVCSGA+PLA+TDNLNFG+PEKPEIFWQ+E+A DG++EAC VL TPVIGGNVSLYNE Sbjct: 485 ARNIVCSGAEPLAVTDNLNFGNPEKPEIFWQIEKAADGISEACNVLSTPVIGGNVSLYNE 544 Query: 549 NASGAIYPTPVVGMVGLVEDTDHITTQAFKQEGDAILLLGVTKAELGGSEFQYAVHGLTE 608 + AIYPTPV+GMVGL+EDT+HITTQ FK GD I ++G T E GSE Q G Sbjct: 545 SNGSAIYPTPVIGMVGLIEDTEHITTQHFKAAGDLIYVIGETFPEFAGSELQKLTEGKIY 604 Query: 609 GRPPELDLATEQKLLDAVLAAIRSGLVRSAHDXXXXXXXXXXXXXCISGS-IGANVEWSA 667 G+ P +DL EQ A+L AIRSGLV+SAHD IS +GA+V + Sbjct: 605 GKAPAIDLEVEQSRQKALLKAIRSGLVQSAHDVSEGGIGVALAESVISSQRLGAHVTLAG 664 Query: 668 GGLRRDVALFSESQSRIVLTAAPGRAEELRAAVAAYGVPAEIIGTVGGDRLRV--SLDGE 725 LFSE+QSR +++ E V A++IG V D + S +G+ Sbjct: 665 ----EPALLFSETQSRFIVSVKKDHQEAFEKLVK----DADLIGEVTSDSVLAVQSQEGQ 716 Query: 726 AVLDEAVAALKTTWEDAIPCLMK 748 + L++ W+ AIPCL+K Sbjct: 717 QWIHAQTEELESAWKGAIPCLLK 739 >B4BRE0.1 B4BRE0_9BACI Phosphoribosylformylglycinamidine synthase II EC=6.3.5.3 Length = 742 Score = 939 bits (2427), Expect = 0.0, Method: Compositional matrix adjust. Identities = 469/744 (63%), Positives = 561/744 (75%), Gaps = 14/744 (1%) Query: 9 EPTAEQIAEQKIYNQFGVSDSEYELITSFMGRKPNYTEIGVFSVMWSEHCAYKNSKPLLG 68 EP A I EQK+Y + G++D E+ I + +GR PNYTE G+FSVMWSEHC+YKNSKP+L Sbjct: 6 EPNAAMIKEQKLYREMGLTDEEFARIEAILGRLPNYTETGIFSVMWSEHCSYKNSKPVLK 65 Query: 69 RFPTSGPRVLMGPGEGAGIVDIGDNQAVVFKIESHNHPSAVEPYQGAATGVGGIIRDIFS 128 +FPT GP VL GPGEGAGIVDIGD AV FKIESHNHPSA+EPYQGAATGVGGIIRD+FS Sbjct: 66 KFPTDGPHVLQGPGEGAGIVDIGDGLAVAFKIESHNHPSAIEPYQGAATGVGGIIRDVFS 125 Query: 129 MGARPVALMNSLRFGKLESDRVKYLFEHVVSGIAGYGNCIGIPTVGGEIMFDNSYDGNPL 188 MGARP+AL+NSLRFG+L S RVKYLFEHVV+GIAGYGNCIGIPTVGGE+ FD +Y+GNPL Sbjct: 126 MGARPIALLNSLRFGELTSPRVKYLFEHVVAGIAGYGNCIGIPTVGGEVQFDPAYEGNPL 185 Query: 189 VNAMCVGLIDHDKIQRGVAKGVGNPVFYVGPPTGRDGIHGATFASVELSEESEAKKTAVQ 248 VNAMCVG+I H+ IQRGVA GVGN V YVG TGRDGIHGATFAS ELSE+SEAK+ AVQ Sbjct: 186 VNAMCVGIIRHEDIQRGVATGVGNTVMYVGAKTGRDGIHGATFASEELSEQSEAKRPAVQ 245 Query: 249 VGDPFMEKLVMESCLELIDSGIVLGIQDMGAAGLTCSSAEMASKAGNGLELYLDQVPQRE 308 VGDPFMEKL++E+CLE + S ++GIQDMGAAGLT SSAEMASK G G+E+ LD VPQRE Sbjct: 246 VGDPFMEKLLLEACLEAVKSDALVGIQDMGAAGLTSSSAEMASKGGFGIEMNLDLVPQRE 305 Query: 309 DGMTPYEMMLSESQERMLFVVEPKDEAQAQEIFDRWGVICRKVGKVTDDGRLKLFHHGEV 368 GMTPYEMMLSESQERML VVE E + IF ++G+ + +GKVTDD L+LF HGEV Sbjct: 306 TGMTPYEMMLSESQERMLLVVEQGREEEIAAIFAKYGLEAKAIGKVTDDKMLRLFFHGEV 365 Query: 369 VGDMPVKALVDECPIYKKPSAVPAYYEENASVDTLRYAEVKDLGGALHTVLASPTVASKA 428 V ++PV AL + P+Y KPSA P YY E ++ T +++D L +LA PT+ASK Sbjct: 366 VAEIPVDALAKDAPVYHKPSAEPDYYREFQAMPTY-IPQIEDYNRTLLGLLAQPTIASKE 424 Query: 429 WVYNQYDYMVRTSTAVRPGSDAAVVTIHGTRKGLAMTTDCNGRYVYLDPEVGGRIAVSEA 488 WVY+QYDYMVRT+T V PGSDAAVV I GT K LA+TTDCN RY+YLDPE+GG+IAV+EA Sbjct: 425 WVYDQYDYMVRTNTVVAPGSDAAVVRIRGTNKALALTTDCNSRYLYLDPEMGGKIAVAEA 484 Query: 489 ARNIVCSGAKPLAITDNLNFGSPEKPEIFWQMERAVDGMAEACRVLDTPVIGGNVSLYNE 548 ARN+VCSGAKPLAITD LNFG+PEKP+IFWQ+E+AVDGM+EACR L TPV+ GNVSLYNE Sbjct: 485 ARNVVCSGAKPLAITDCLNFGNPEKPDIFWQLEKAVDGMSEACRTLGTPVVSGNVSLYNE 544 Query: 549 NASGAIYPTPVVGMVGLVEDTDHITTQAFKQEGDAILLLGVTKAELGGSEFQYAVHGLTE 608 A+YPTPVVGMVGLV+D H+TTQ FKQ GD I ++G K E GGSE Q + G Sbjct: 545 TNGEAVYPTPVVGMVGLVDDLSHVTTQPFKQAGDLIYVIGEAKPEFGGSELQKWLEGRIF 604 Query: 609 GRPPELDLATEQKLLDAVLAAIRSGLVRSAHDXXXXXXXXXXXXXCISGS-IGANVEWSA 667 G+ PELDLA E +L AIR+G+V SAHD I S +GANV S Sbjct: 605 GKAPELDLAVEASRQRQLLTAIRAGVVASAHDVAEGGLAVALAECVIGASGLGANVTVS- 663 Query: 668 GGLRRDVALFSESQSRIVLTAAPGRAEELRAAVAAYGVPAEIIGTVGGDRLRVSLDGE-- 725 G L + LFSE+QSR V++ E V A++IG V D + ++++GE Sbjct: 664 GDLVSE--LFSETQSRFVVSVKKEHQEAFEQLVE-----AKLIGEVTNDSI-LTVNGEHG 715 Query: 726 -AVLDEAVAALKTTWEDAIPCLMK 748 V+ +V ++ W+ AIPCL+K Sbjct: 716 GTVIRLSVDEMRNVWKGAIPCLLK 739 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.135 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 4,540,413,843 Number of extensions: 199517275 Number of successful extensions: 473999 Number of sequences better than 1.0e-05: 1598 Number of HSP's gapped: 466087 Number of HSP's successfully gapped: 1674 Length of query: 748 Length of database: 3,060,696,203 Length adjustment: 144 Effective length of query: 604 Effective length of database: 1,704,070,043 Effective search space: 1029258305972 Effective search space used: 1029258305972 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 135 (56.6 bits)