BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0442.0006.p (229 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KA78.1 B3KA78_9BACI Phosphoribosylformylglycinamidine synthase... 409 e-112 B1D8Y4.1 B1D8Y4_9BACL Phosphoribosylformylglycinamidine synthase... 362 2e-98 C0ZKC5.1 PURQ_BREBN Phosphoribosylformylglycinamidine synthase 1... 340 8e-92 A3I467.1 A3I467_9BACI Phosphoribosylformylglycinamidine synthase... 330 8e-89 B1HTV3.1 PURQ_LYSSC Phosphoribosylformylglycinamidine synthase 1... 325 1e-87 >B3KA78.1 B3KA78_9BACI Phosphoribosylformylglycinamidine synthase I EC=6.3.5.3 Length = 229 Score = 409 bits (1050), Expect = e-112, Method: Compositional matrix adjust. Identities = 189/229 (82%), Positives = 210/229 (91%) Query: 1 MKFAVLVFPGSNCDIDCYKAVEDSLGEPVEYVWHTATDLSAYDCILVPGGFSYGDYLRCG 60 M+FAVLVFPGSNCDIDCYKAVE+++G+PV+YVWHTATDLS YDCILVPGGFSYGDYLRCG Sbjct: 1 MRFAVLVFPGSNCDIDCYKAVEETIGQPVDYVWHTATDLSPYDCILVPGGFSYGDYLRCG 60 Query: 61 AISRFAPVMAEVAKAAEQGKFVLGICNGFQILTEAGLLPGALRRNMSMKFRCHDTVLKVV 120 AISRFAPVM EVAKAAE+GK++LGICNGFQILTEAGLLPGALRRN SMKFRCHDTVLKV Sbjct: 61 AISRFAPVMNEVAKAAEEGKYILGICNGFQILTEAGLLPGALRRNDSMKFRCHDTVLKVN 120 Query: 121 NNTTPFTVDYAKDEEIVIPIAHGEGNYYCDEETLAGLKANNQIVFTYSDNPNGSVEHIAG 180 NNTTPFT DYA+ +EIVIPIAHGEGNYYCDEETL L+ N QIVFTY DNPNGS+E IAG Sbjct: 121 NNTTPFTRDYAEGQEIVIPIAHGEGNYYCDEETLQKLRDNRQIVFTYQDNPNGSIEDIAG 180 Query: 181 ICNVQGNVVGMMPHPERAANSLLGSEDGKRMFTSILKTWRDRYDTASIR 229 ICN +GNV+GMMPHPERA +SLLGS+DGK MFTSIL+ WRD + A++R Sbjct: 181 ICNERGNVIGMMPHPERAVSSLLGSDDGKAMFTSILQAWRDTHGAANVR 229 >B1D8Y4.1 B1D8Y4_9BACL Phosphoribosylformylglycinamidine synthase I EC=6.3.5.3 Length = 231 Score = 362 bits (929), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 171/228 (75%), Positives = 194/228 (85%), Gaps = 2/228 (0%) Query: 1 MKFAVLVFPGSNCDIDCYKAVEDSLGEPVEYVWHTATDLSAYDCILVPGGFSYGDYLRCG 60 MKFAVLVFPGSNCDIDC+KAVED++G+ V+YVWHTATDLS YD ILVPGGFSYGDYLRCG Sbjct: 1 MKFAVLVFPGSNCDIDCFKAVEDTIGQEVDYVWHTATDLSGYDAILVPGGFSYGDYLRCG 60 Query: 61 AISRFAPVMAEVAKAAEQGKFVLGICNGFQILTEAGLLPGALRRNMSMKFRCHDTVLKVV 120 A++ +APVM EV KAAEQGKF+LGICNGFQILTEA LLPGAL RN +KFRC +L+VV Sbjct: 61 AMASYAPVMNEVVKAAEQGKFILGICNGFQILTEANLLPGALIRNTGLKFRCQQQLLEVV 120 Query: 121 NNTTPFTVDYAKDEEIVIPIAHGEGNYYCDEETLAGLKANNQIVFTYS--DNPNGSVEHI 178 NN T FT Y++ E I IPIAHGEGNYYCD+ TLA LKANNQIVF Y+ NPNGSVE+I Sbjct: 121 NNGTAFTNQYSQGEIIDIPIAHGEGNYYCDDATLAELKANNQIVFRYAGDTNPNGSVENI 180 Query: 179 AGICNVQGNVVGMMPHPERAANSLLGSEDGKRMFTSILKTWRDRYDTA 226 AGI N +GNVVGMMPHPERA + +LGSEDGKRMFTSIL WR+++ A Sbjct: 181 AGISNKKGNVVGMMPHPERAVDQILGSEDGKRMFTSILNAWREQHGAA 228 >C0ZKC5.1 PURQ_BREBN Phosphoribosylformylglycinamidine synthase 1 EC=6.3.5.3 Length = 230 Score = 340 bits (871), Expect = 8e-92, Method: Compositional matrix adjust. Identities = 157/223 (70%), Positives = 187/223 (83%), Gaps = 1/223 (0%) Query: 1 MKFAVLVFPGSNCDIDCYKAVEDSLGEPVEYVWHTATDLSAYDCILVPGGFSYGDYLRCG 60 M+ AV+VFPGSN D+D + AVED +G PV+YVWH+ TDLS YD IL+PGGFSYGDYLRCG Sbjct: 1 MRVAVIVFPGSNADVDLFNAVEDVMGVPVDYVWHSDTDLSKYDAILLPGGFSYGDYLRCG 60 Query: 61 AISRFAPVMAEVAKAAEQGKFVLGICNGFQILTEAGLLPGALRRNMSMKFRCHDTVLKVV 120 A++RF+PVM +V KAA++GK ++GICNGFQILTE GLLPGAL RN S+KFRC + L+V Sbjct: 61 AVARFSPVMEQVVKAADEGKLIMGICNGFQILTEVGLLPGALLRNRSLKFRCKLSELRVE 120 Query: 121 NNTTPFTVDYAKDEEIVIPIAHGEGNYYCDEETLAGLKANNQIVFTY-SDNPNGSVEHIA 179 NN T FT D+A E I IPIAHGEGNYYCDEETLA LKAN QIVF Y +NPNGS+E IA Sbjct: 121 NNDTSFTRDFAAGEVIQIPIAHGEGNYYCDEETLAKLKANKQIVFRYHGENPNGSLEDIA 180 Query: 180 GICNVQGNVVGMMPHPERAANSLLGSEDGKRMFTSILKTWRDR 222 GICN +GNV+GMMPHPERA +S + S+DG+RMFTSILKTWR++ Sbjct: 181 GICNERGNVLGMMPHPERAVHSWMTSDDGRRMFTSILKTWREQ 223 >A3I467.1 A3I467_9BACI Phosphoribosylformylglycinamidine synthase subunit I EC=6.3.5.3 Length = 227 Score = 330 bits (845), Expect = 8e-89, Method: Compositional matrix adjust. Identities = 158/224 (70%), Positives = 182/224 (81%), Gaps = 1/224 (0%) Query: 1 MKFAVLVFPGSNCDIDCYKAVEDSLGEPVEYVWHTATDLSAYDCILVPGGFSYGDYLRCG 60 MKFAVLVFPGSNCDID Y A++D LGE VEYVWHTATDLS +D +LVPGGFSYGDYLRCG Sbjct: 1 MKFAVLVFPGSNCDIDMYHAIKDELGEEVEYVWHTATDLSGFDGVLVPGGFSYGDYLRCG 60 Query: 61 AISRFAPVMAEVAKAAEQGKFVLGICNGFQILTEAGLLPGALRRNMSMKFRCHDTVLKVV 120 A++ + +MAEV KAA+ GK VLG+CNGFQILTEAGLLPGAL RN ++KF C LKV Sbjct: 61 AMANQSNIMAEVKKAADAGKPVLGVCNGFQILTEAGLLPGALLRNKNLKFMCRTVKLKVE 120 Query: 121 NNTTPFTVDYAKDEEIVIPIAHGEGNYYCDEETLAGLKANNQIVFTYS-DNPNGSVEHIA 179 NN T FT Y +D+ I IPIAHGEGNYYCDEETL LK NNQIVFTYS DNPNGS+E IA Sbjct: 121 NNNTLFTNQYEQDQIIHIPIAHGEGNYYCDEETLQSLKDNNQIVFTYSGDNPNGSLEDIA 180 Query: 180 GICNVQGNVVGMMPHPERAANSLLGSEDGKRMFTSILKTWRDRY 223 GI N +GNV+GMMPHPERA ++L+G DG +F SI+K WR+ + Sbjct: 181 GIINERGNVLGMMPHPERAVDALVGGADGLAVFKSIVKQWRENH 224 >B1HTV3.1 PURQ_LYSSC Phosphoribosylformylglycinamidine synthase 1 EC=6.3.5.3 Length = 227 Score = 325 bits (834), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 156/224 (69%), Positives = 180/224 (80%), Gaps = 1/224 (0%) Query: 1 MKFAVLVFPGSNCDIDCYKAVEDSLGEPVEYVWHTATDLSAYDCILVPGGFSYGDYLRCG 60 MKFAVLVFPGSNCDID Y A++D LGE VEYVWHTATDLS +D +LVPGGFSYGDYLRCG Sbjct: 1 MKFAVLVFPGSNCDIDMYHAIKDELGEEVEYVWHTATDLSGFDGVLVPGGFSYGDYLRCG 60 Query: 61 AISRFAPVMAEVAKAAEQGKFVLGICNGFQILTEAGLLPGALRRNMSMKFRCHDTVLKVV 120 A++ + +MAEV K A+ GK VLG+CNGFQILTEAGLLPGAL RN ++KF C LKV Sbjct: 61 AMANQSNIMAEVKKVADAGKPVLGVCNGFQILTEAGLLPGALLRNTNLKFMCRTVQLKVE 120 Query: 121 NNTTPFTVDYAKDEEIVIPIAHGEGNYYCDEETLAGLKANNQIVFTYS-DNPNGSVEHIA 179 NN T FT Y + + I IPIAHGEGNYYCDEETL LK NNQIVFTYS DNPNGS+E IA Sbjct: 121 NNNTLFTNQYEQGQIIHIPIAHGEGNYYCDEETLQSLKDNNQIVFTYSGDNPNGSLEDIA 180 Query: 180 GICNVQGNVVGMMPHPERAANSLLGSEDGKRMFTSILKTWRDRY 223 GI N +GNV+GMMPHPERA ++L+G DG +F SI+K WR+ + Sbjct: 181 GIINERGNVLGMMPHPERAVDALVGGADGLAVFKSIVKQWRENH 224 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.137 0.424 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,443,471,347 Number of extensions: 60594472 Number of successful extensions: 145064 Number of sequences better than 1.0e-05: 1545 Number of HSP's gapped: 142364 Number of HSP's successfully gapped: 1545 Length of query: 229 Length of database: 3,060,696,203 Length adjustment: 131 Effective length of query: 98 Effective length of database: 1,826,543,238 Effective search space: 179001237324 Effective search space used: 179001237324 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 129 (54.3 bits)