BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0442.0004.p (303 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KA76.1 B3KA76_9BACI Phosphoribosylaminoimidazolesuccinocarboxa... 438 e-121 B1D8Y2.1 B1D8Y2_9BACL Phosphoribosylaminoimidazolesuccinocarboxa... 437 e-121 C0UZB2.1 C0UZB2_9BACT Phosphoribosylaminoimidazole-succinocarbox... 285 3e-75 B9XMC0.1 B9XMC0_9BACT Phosphoribosylaminoimidazole-succinocarbox... 273 2e-71 B1GYZ5.1 B1GYZ5_UNCTG Phosphoribosylaminoimidazole-succinocarbox... 272 3e-71 >B3KA76.1 B3KA76_9BACI Phosphoribosylaminoimidazolesuccinocarboxamide synthase EC=6.3.2.6 Length = 296 Score = 438 bits (1126), Expect = e-121, Method: Compositional matrix adjust. Identities = 209/296 (70%), Positives = 238/296 (80%) Query: 8 MTYPAVSTAVDLVNAPLLYKGKVRELYDLGEEVLIVVTDRISAFDYVLDPAVPEKGNVLN 67 MT PA+STA LVN PLLYKGKVRELYDLGE VLIVVTDRISAFDYVL+P VP KG VLN Sbjct: 1 MTLPALSTATHLVNVPLLYKGKVRELYDLGEHVLIVVTDRISAFDYVLEPPVPAKGTVLN 60 Query: 68 RLSAFWFGQTSELMENHVVHIDVDRLGGIVKDREALRNRIMVVRKAERIDIECVVRGCIT 127 +LSAFWF QT +L+ NHVVH DV+ LG VKD++ L RIMV R+AERIDIECVVRG IT Sbjct: 61 KLSAFWFEQTEQLIRNHVVHTDVNLLGDAVKDKDLLDGRIMVCRRAERIDIECVVRGYIT 120 Query: 128 GGGWRQYQETGKVNGIGLPAGLRKNAQLSQPIFTPAAKNDVGHDEDIPFEKMQELIGXXX 187 GGGWRQYQ +G+VNGI LP GLRKN +PIFTPAAKNDVGHDEDIP +M+EL+G Sbjct: 121 GGGWRQYQSSGEVNGIQLPEGLRKNEAFPEPIFTPAAKNDVGHDEDIPLSRMKELVGEEL 180 Query: 188 XXXXXXXXXXXXXXXREYCEERGIILADCKFEFGLLDGKVILIDEIFTPDASRFWAKDKY 247 R+YC ++GIILADCKFEFGL++G+++LIDEIFTPD+SRFW + Y Sbjct: 181 ALQLQDKSLMLYKFARDYCRKQGIILADCKFEFGLINGEIVLIDEIFTPDSSRFWDEKNY 240 Query: 248 ALDIEIDSMDKEPVRTYLSASSWDKNSTPDPLPAEVVEETTRRYLDIYHRLTGKTL 303 ALDIEIDSMDKEPVRTYL++S WDKNS PDPLP VVEETTRRY DIY R+TG +L Sbjct: 241 ALDIEIDSMDKEPVRTYLASSDWDKNSEPDPLPQAVVEETTRRYSDIYSRITGVSL 296 >B1D8Y2.1 B1D8Y2_9BACL Phosphoribosylaminoimidazolesuccinocarboxamide synthase EC=6.3.2.6 Length = 299 Score = 437 bits (1125), Expect = e-121, Method: Compositional matrix adjust. Identities = 208/292 (71%), Positives = 234/292 (80%) Query: 12 AVSTAVDLVNAPLLYKGKVRELYDLGEEVLIVVTDRISAFDYVLDPAVPEKGNVLNRLSA 71 A+STA D + APLLYKGKVRELYDLGE LIVVTDRISAFDYVLDPAVP+KGNVLNRLSA Sbjct: 7 ALSTAADYIKAPLLYKGKVRELYDLGEHYLIVVTDRISAFDYVLDPAVPQKGNVLNRLSA 66 Query: 72 FWFGQTSELMENHVVHIDVDRLGGIVKDREALRNRIMVVRKAERIDIECVVRGCITGGGW 131 FWF QT+++ NHVVH DV++LG IV E L++RIMV +KAERIDIECVVRG ITGGGW Sbjct: 67 FWFEQTADIQTNHVVHTDVEKLGDIVTAPELLKDRIMVTKKAERIDIECVVRGYITGGGW 126 Query: 132 RQYQETGKVNGIGLPAGLRKNAQLSQPIFTPAAKNDVGHDEDIPFEKMQELIGXXXXXXX 191 RQYQ+T +NGI LP G+RKN + QPIFTPAAKNDVGHDEDIPFE+MQE++G Sbjct: 127 RQYQQTSAINGIQLPEGMRKNERFPQPIFTPAAKNDVGHDEDIPFERMQEMVGAELAEEL 186 Query: 192 XXXXXXXXXXXREYCEERGIILADCKFEFGLLDGKVILIDEIFTPDASRFWAKDKYALDI 251 EYC + GIILADCKFEFGL+DGKVILIDEIFTPD+SRFW + YA DI Sbjct: 187 KGRSIKLYEFAHEYCAKHGIILADCKFEFGLIDGKVILIDEIFTPDSSRFWGEKSYAYDI 246 Query: 252 EIDSMDKEPVRTYLSASSWDKNSTPDPLPAEVVEETTRRYLDIYHRLTGKTL 303 EIDSMDKEPVRTYL S WD++S P PLP VV ETT RYLDIY RLTG++L Sbjct: 247 EIDSMDKEPVRTYLLGSDWDRDSKPAPLPESVVNETTNRYLDIYSRLTGRSL 298 >C0UZB2.1 C0UZB2_9BACT Phosphoribosylaminoimidazole-succinocarboxamide synthase EC=6.3.2.6 Length = 296 Score = 285 bits (730), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 139/294 (47%), Positives = 195/294 (66%), Gaps = 3/294 (1%) Query: 13 VSTAVDLVNAP---LLYKGKVRELYDLGEEVLIVVTDRISAFDYVLDPAVPEKGNVLNRL 69 +S AV N P L+++GKVR+ YDLG+ +L+V TDRISAFD+VL +P+KG VL+++ Sbjct: 1 MSKAVTETNLPGINLIHRGKVRDTYDLGDSLLMVATDRISAFDWVLPTPIPDKGKVLSQI 60 Query: 70 SAFWFGQTSELMENHVVHIDVDRLGGIVKDREALRNRIMVVRKAERIDIECVVRGCITGG 129 S FWF + ++++ NH + D++ ++ + LR R M+V+KA RID ECVVRG ITG Sbjct: 61 SVFWFEKLADIVPNHFITDDINNYSHLLPYSDVLRGRSMIVKKANRIDYECVVRGYITGS 120 Query: 130 GWRQYQETGKVNGIGLPAGLRKNAQLSQPIFTPAAKNDVGHDEDIPFEKMQELIGXXXXX 189 GW +Y++ G V G +P GLR +L +PIFTPA KN+ GHDE+I +E ++ +G Sbjct: 121 GWAEYKKQGTVAGKPMPEGLRDGDKLPEPIFTPARKNEEGHDENITYEILESEVGSDLAS 180 Query: 190 XXXXXXXXXXXXXREYCEERGIILADCKFEFGLLDGKVILIDEIFTPDASRFWAKDKYAL 249 R+Y E RG+I+AD KFEFG +DG++ LIDE+ TPD+SRFW + +Y Sbjct: 181 QLRDISIQLYQDGRDYAETRGVIIADTKFEFGFVDGQLTLIDELLTPDSSRFWLESEYRP 240 Query: 250 DIEIDSMDKEPVRTYLSASSWDKNSTPDPLPAEVVEETTRRYLDIYHRLTGKTL 303 + S+DK+ VR +L+ S WDKNS P LP EVVE T +RYL+ Y LTGK L Sbjct: 241 GESLPSLDKQYVRDWLTQSGWDKNSQPPELPDEVVEATRQRYLEAYRMLTGKEL 294 >B9XMC0.1 B9XMC0_9BACT Phosphoribosylaminoimidazole-succinocarboxamide synthase EC=6.3.2.6 Length = 297 Score = 273 bits (697), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 135/288 (46%), Positives = 182/288 (63%), Gaps = 1/288 (0%) Query: 17 VDLVNAPLLYKGKVRELYDLGEEVLIVVTDRISAFDYVLDPAVPEKGNVLNRLSAFWFGQ 76 +DL L GKVRE++DLG+ +L V TDRISAFD ++ +P KG VL ++S FWF Q Sbjct: 9 LDLPGIRKLKSGKVREVFDLGDRLLFVATDRISAFDCIMPNGIPRKGEVLTQISYFWFDQ 68 Query: 77 TSELMENHVVHIDVDRLGGIVKDREA-LRNRIMVVRKAERIDIECVVRGCITGGGWRQYQ 135 + NH++ D L +++ A L R M+V+KA+ + IECVVRG + G GW++YQ Sbjct: 69 MASFQPNHLLSKPNDSLPILLQPYAAQLAGRCMIVKKAQPLAIECVVRGYLAGSGWKEYQ 128 Query: 136 ETGKVNGIGLPAGLRKNAQLSQPIFTPAAKNDVGHDEDIPFEKMQELIGXXXXXXXXXXX 195 E V GI LPAGL+++++L +PIFTPA K + GHDE+I FE+ +L+G Sbjct: 129 ERQTVCGIKLPAGLKESSELPEPIFTPATKAESGHDENISFEEASKLVGSDIAEKARSAS 188 Query: 196 XXXXXXXREYCEERGIILADCKFEFGLLDGKVILIDEIFTPDASRFWAKDKYALDIEIDS 255 REY +RGII+AD KFEFGL D +++LIDE+ TPD+SRFW D+Y S Sbjct: 189 MKIYKFAREYARQRGIIIADTKFEFGLFDDELLLIDEVLTPDSSRFWPADQYQPGRSQPS 248 Query: 256 MDKEPVRTYLSASSWDKNSTPDPLPAEVVEETTRRYLDIYHRLTGKTL 303 DK+ VR YL WDK LP EVVE++ +YLD YHRLTG+ L Sbjct: 249 FDKQFVRDYLETLDWDKTPPAPKLPPEVVEKSQAKYLDAYHRLTGQLL 296 >B1GYZ5.1 B1GYZ5_UNCTG Phosphoribosylaminoimidazole-succinocarboxamide synthase Length = 292 Score = 272 bits (695), Expect = 3e-71, Method: Compositional matrix adjust. Identities = 132/289 (45%), Positives = 190/289 (65%), Gaps = 1/289 (0%) Query: 13 VSTAVDLVNAPLLYKGKVRELYDLGEEVLIVVTDRISAFDYVLDPAVPEKGNVLNRLSAF 72 +S D ++ PL++KGKVR++Y+LG+ LIV +DRISAFDYV+ +P+KG VL++LS F Sbjct: 1 MSNKEDSISLPLVHKGKVRDVYNLGKSYLIVASDRISAFDYVIPTIIPDKGRVLHKLSMF 60 Query: 73 WFGQTSELMENHVVHIDVDRLGGIVKDREALRNRIMVVRKAERIDIECVVRGCITGGGWR 132 WF ++ NH++ + + +K E LR+R M+V+KA+R+DIEC+VRG + G GW+ Sbjct: 61 WFDFIQGIVPNHIITGNFESFPLSLKQYEYLRDRSMIVKKAKRVDIECIVRGYLAGSGWK 120 Query: 133 QYQETGKVNGIGLPAGLRKNAQLSQPIFTPAAKNDVG-HDEDIPFEKMQELIGXXXXXXX 191 +YQ++ V GI LP GL+++++L + +FTP++K + G HDE+I FE+M E +G Sbjct: 121 EYQKSQTVCGIKLPVGLKESSKLPESVFTPSSKEEGGKHDENISFEEMVERVGKDTAESL 180 Query: 192 XXXXXXXXXXXREYCEERGIILADCKFEFGLLDGKVILIDEIFTPDASRFWAKDKYALDI 251 EY GIILAD K EFG D ++ILIDEIFTPD+SRFW KY Sbjct: 181 RRISLELYKKVSEYSFLNGIILADTKLEFGFYDNQLILIDEIFTPDSSRFWETGKYEEGK 240 Query: 252 EIDSMDKEPVRTYLSASSWDKNSTPDPLPAEVVEETTRRYLDIYHRLTG 300 DS+DK+ VR YL WDK+S LP +VVE+T +Y+ +Y +LTG Sbjct: 241 SQDSLDKQYVRDYLERIKWDKSSPAPELPKDVVEKTMEKYISVYEKLTG 289 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.140 0.417 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,763,089,109 Number of extensions: 71840278 Number of successful extensions: 158669 Number of sequences better than 1.0e-05: 888 Number of HSP's gapped: 155691 Number of HSP's successfully gapped: 903 Length of query: 303 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 168 Effective length of database: 1,788,859,178 Effective search space: 300528341904 Effective search space used: 300528341904 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 131 (55.1 bits)