BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0442.0003.p (431 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KA75.1 B3KA75_9BACI Adenylosuccinate lyase 803 0.0 B1D8Y1.1 B1D8Y1_9BACL Adenylosuccinate lyase 790 0.0 C0ZK65.1 C0ZK65_BREBN Adenylosuccinate lyase EC=4.3.2.2 703 0.0 Q2B0S3.1 Q2B0S3_9BACI Adenylosuccinate lyase EC=4.3.2.2 703 0.0 Q9KF61.1 Q9KF61_BACHD Adenylosuccinate lyase 699 0.0 >B3KA75.1 B3KA75_9BACI Adenylosuccinate lyase Length = 431 Score = 803 bits (2074), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/430 (88%), Positives = 405/430 (94%) Query: 1 MIERYSRPEMRAIWTEENKFNAWLEVELCACEAWAELGVIPHEDAAKLRKNAKFDIGRIN 60 MIERYSRPEMRAIWTEENKF AWLEVELCACEAWA+LGVIP ED KLR+NA F+I RI Sbjct: 1 MIERYSRPEMRAIWTEENKFRAWLEVELCACEAWADLGVIPKEDTVKLRQNATFNIDRIY 60 Query: 61 EIELETRHDVIAFTRAVSESLGAERKWVHYGLTSTDVVDTALGYLLRQANEILEKDIINF 120 EIE ETRHDVIAFTRAVSESLG ERKWVHYGLTSTDVVDTA+GYLL+QAN+ILE+DI+ F Sbjct: 61 EIEQETRHDVIAFTRAVSESLGEERKWVHYGLTSTDVVDTAMGYLLKQANDILEQDILRF 120 Query: 121 IEILKDKALAYKDTPMMGRTHGVHAEPTTFGLKMALWYEEMKRNLERFRHAANGVQFGKI 180 I ILK+KALAYK TPMMGRTHGVHAEPTTFGLKMALW+EEM RNLERFRHAA+GVQ+GKI Sbjct: 121 IGILKEKALAYKHTPMMGRTHGVHAEPTTFGLKMALWHEEMIRNLERFRHAADGVQYGKI 180 Query: 181 SGAVGTYANIDPFVEEFVCRKLGTSPAPISTQTLQRDRHAEYMAALALVATSLDKFATEI 240 SGAVGTYANIDP VEEFVCRKLGT APISTQTLQRDRHAEYMA LAL+ATSL+KFATE+ Sbjct: 181 SGAVGTYANIDPSVEEFVCRKLGTKAAPISTQTLQRDRHAEYMATLALIATSLEKFATEV 240 Query: 241 RALQKSEIREVEEAFAKGQKGSSAMPHKRNPIGCENISGLSRVIRGHMMTAYENVPLWHE 300 RALQKSE+REVEEAFAKGQKGSSAMPHKRNPIG ENISGL+RVIRGHM++AYENV LWHE Sbjct: 241 RALQKSEVREVEEAFAKGQKGSSAMPHKRNPIGSENISGLARVIRGHMVSAYENVSLWHE 300 Query: 301 RDISHSSVERIILPDATMLLNYMLNRFGNIVKNLTVFPDNMKRNMNRTFGVPFSGRILTK 360 RDISHSSVERIILPDATMLLNYMLNRFGNIVKNLTVFP+NMKRNM RT+GVPFSGRILTK Sbjct: 301 RDISHSSVERIILPDATMLLNYMLNRFGNIVKNLTVFPENMKRNMARTYGVPFSGRILTK 360 Query: 361 LIDKGFSREQAYDTVQPRAMQAWEEQTQFRDIVEATPEITAVLSPEEIEDAFNPSWHLKH 420 LIDKGFSREQAYDTVQPRAMQAWEEQ QFR+IVE+TPEIT VLS EEIEDAFNPSWHLKH Sbjct: 361 LIDKGFSREQAYDTVQPRAMQAWEEQRQFREIVESTPEITEVLSAEEIEDAFNPSWHLKH 420 Query: 421 VDTIFRKLEL 430 VDTIF KL L Sbjct: 421 VDTIFAKLGL 430 >B1D8Y1.1 B1D8Y1_9BACL Adenylosuccinate lyase Length = 431 Score = 790 bits (2040), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/430 (86%), Positives = 399/430 (92%) Query: 1 MIERYSRPEMRAIWTEENKFNAWLEVELCACEAWAELGVIPHEDAAKLRKNAKFDIGRIN 60 M+ERYSRPEMRAIWTE+NKF AWLEVELC+CEAW ELGVIP ED LRK A F+I RI Sbjct: 1 MLERYSRPEMRAIWTEQNKFQAWLEVELCSCEAWVELGVIPAEDVEALRKAATFNIDRIY 60 Query: 61 EIELETRHDVIAFTRAVSESLGAERKWVHYGLTSTDVVDTALGYLLRQANEILEKDIINF 120 EIE ETRHDVIAFTRAVSE++G ERKWVHYGLTSTDVVDTA GYLL QAN IL+KDI F Sbjct: 61 EIEQETRHDVIAFTRAVSETVGPERKWVHYGLTSTDVVDTANGYLLLQANAILKKDIERF 120 Query: 121 IEILKDKALAYKDTPMMGRTHGVHAEPTTFGLKMALWYEEMKRNLERFRHAANGVQFGKI 180 I IL++KA+ YKDTPMMGRTHGVHAEPTTFGLKMALW+EEMKRNLERF HAANGVQFGKI Sbjct: 121 ISILREKAIQYKDTPMMGRTHGVHAEPTTFGLKMALWHEEMKRNLERFEHAANGVQFGKI 180 Query: 181 SGAVGTYANIDPFVEEFVCRKLGTSPAPISTQTLQRDRHAEYMAALALVATSLDKFATEI 240 SGAVGTYANIDPFVEEFVC+KLG SPAPISTQTLQRDRHAEYMA LALVATSLDKFATEI Sbjct: 181 SGAVGTYANIDPFVEEFVCKKLGISPAPISTQTLQRDRHAEYMATLALVATSLDKFATEI 240 Query: 241 RALQKSEIREVEEAFAKGQKGSSAMPHKRNPIGCENISGLSRVIRGHMMTAYENVPLWHE 300 RALQKSE REVEEAFAKGQKGSSAMPHKRNPIGCENISGLSRVIRGHM+TAYENVPLWHE Sbjct: 241 RALQKSEFREVEEAFAKGQKGSSAMPHKRNPIGCENISGLSRVIRGHMLTAYENVPLWHE 300 Query: 301 RDISHSSVERIILPDATMLLNYMLNRFGNIVKNLTVFPDNMKRNMNRTFGVPFSGRILTK 360 RDISHSS ER+ILPDATMLLNYMLNR GNI++NLTVFP+NMK+NM RTFGVPFSGR++TK Sbjct: 301 RDISHSSAERVILPDATMLLNYMLNRLGNIIQNLTVFPENMKKNMQRTFGVPFSGRVMTK 360 Query: 361 LIDKGFSREQAYDTVQPRAMQAWEEQTQFRDIVEATPEITAVLSPEEIEDAFNPSWHLKH 420 LIDKG SREQAYDTVQPRAMQAWEEQ QFRDI+E+TPEIT++LS EEI+DAFNP+WHLKH Sbjct: 361 LIDKGLSREQAYDTVQPRAMQAWEEQRQFRDIIESTPEITSLLSAEEIDDAFNPAWHLKH 420 Query: 421 VDTIFRKLEL 430 V+TIF +L L Sbjct: 421 VNTIFTRLGL 430 >C0ZK65.1 C0ZK65_BREBN Adenylosuccinate lyase EC=4.3.2.2 Length = 431 Score = 703 bits (1815), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/431 (77%), Positives = 373/431 (86%) Query: 1 MIERYSRPEMRAIWTEENKFNAWLEVELCACEAWAELGVIPHEDAAKLRKNAKFDIGRIN 60 MIERYSRPEMRAIWTEENKF AWLEVE+ ACEAW++LGVIP ED KL A FDI RI Sbjct: 1 MIERYSRPEMRAIWTEENKFKAWLEVEILACEAWSKLGVIPEEDVKKLWDKATFDINRIY 60 Query: 61 EIELETRHDVIAFTRAVSESLGAERKWVHYGLTSTDVVDTALGYLLRQANEILEKDIINF 120 EIE ETRHDV+AFTRAVSE+LG E+KWVHYGLTSTDVVDTAL YLLRQANEILEKDI +F Sbjct: 61 EIEEETRHDVVAFTRAVSETLGEEKKWVHYGLTSTDVVDTALSYLLRQANEILEKDIQDF 120 Query: 121 IEILKDKALAYKDTPMMGRTHGVHAEPTTFGLKMALWYEEMKRNLERFRHAANGVQFGKI 180 IEIL DKA +KDT MGRTHGVHAEPTTFGLK+ALWYEEMKRNL RF+ A V +GKI Sbjct: 121 IEILADKAREHKDTVCMGRTHGVHAEPTTFGLKLALWYEEMKRNLARFQAAKKEVAYGKI 180 Query: 181 SGAVGTYANIDPFVEEFVCRKLGTSPAPISTQTLQRDRHAEYMAALALVATSLDKFATEI 240 SGAVGTYANIDPFVE +VC KLG S APISTQTLQRDRHAEYMA LAL+ATSL+KFATEI Sbjct: 181 SGAVGTYANIDPFVEAYVCEKLGLSAAPISTQTLQRDRHAEYMATLALIATSLEKFATEI 240 Query: 241 RALQKSEIREVEEAFAKGQKGSSAMPHKRNPIGCENISGLSRVIRGHMMTAYENVPLWHE 300 R LQKSE+REVEEAFAKGQKGSSAMPHKRNPIG ENI GL+RVIRGHM+T+YENV LWHE Sbjct: 241 RGLQKSEMREVEEAFAKGQKGSSAMPHKRNPIGSENICGLARVIRGHMLTSYENVSLWHE 300 Query: 301 RDISHSSVERIILPDATMLLNYMLNRFGNIVKNLTVFPDNMKRNMNRTFGVPFSGRILTK 360 RDISHSS ER+ILPDAT LNYML RF NIVKNLTVFP+NMKRNM+RTF + +S +++ K Sbjct: 301 RDISHSSAERVILPDATQALNYMLRRFMNIVKNLTVFPENMKRNMDRTFELIYSQQVMLK 360 Query: 361 LIDKGFSREQAYDTVQPRAMQAWEEQTQFRDIVEATPEITAVLSPEEIEDAFNPSWHLKH 420 LI+KG SREQAYDTVQPRAMQAWEEQ FR IV+ +++ LS EE+++ F+ +HLKH Sbjct: 361 LIEKGMSREQAYDTVQPRAMQAWEEQRSFRAIVDEDATVSSTLSKEELDECFDYRYHLKH 420 Query: 421 VDTIFRKLELI 431 VDTIF++L LI Sbjct: 421 VDTIFQRLGLI 431 >Q2B0S3.1 Q2B0S3_9BACI Adenylosuccinate lyase EC=4.3.2.2 Length = 430 Score = 703 bits (1815), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/430 (76%), Positives = 378/430 (87%) Query: 1 MIERYSRPEMRAIWTEENKFNAWLEVELCACEAWAELGVIPHEDAAKLRKNAKFDIGRIN 60 MI RY+RPEM AIWTEEN+F AWLEVE+ ACEAWAELG IP ED K+R+NA FDI RIN Sbjct: 1 MIGRYTRPEMGAIWTEENRFKAWLEVEILACEAWAELGDIPKEDVQKIRENASFDIERIN 60 Query: 61 EIELETRHDVIAFTRAVSESLGAERKWVHYGLTSTDVVDTALGYLLRQANEILEKDIINF 120 EIE ETRHDV+AFTRAVSE+LG ERKWVHYGLTSTDVVDTAL YL++QAN IL +D+ NF Sbjct: 61 EIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTALSYLIKQANSILLQDLENF 120 Query: 121 IEILKDKALAYKDTPMMGRTHGVHAEPTTFGLKMALWYEEMKRNLERFRHAANGVQFGKI 180 +EILK+KA +K T MMGRTHGVHAEPTTFGLK+ALWYEEMKRNLERF+ AA+GV+FGK+ Sbjct: 121 VEILKNKAKEHKYTVMMGRTHGVHAEPTTFGLKLALWYEEMKRNLERFKQAASGVEFGKM 180 Query: 181 SGAVGTYANIDPFVEEFVCRKLGTSPAPISTQTLQRDRHAEYMAALALVATSLDKFATEI 240 SGAVGTYANI+PFVE +VC KLG PAPISTQTLQRDRHA YMAA++L+ATS++KFA EI Sbjct: 181 SGAVGTYANINPFVESYVCEKLGLQPAPISTQTLQRDRHAHYMAAISLIATSIEKFAVEI 240 Query: 241 RALQKSEIREVEEAFAKGQKGSSAMPHKRNPIGCENISGLSRVIRGHMMTAYENVPLWHE 300 R LQKSE REVEE FAKGQKGSSAMPHKRNPIG EN++GL+RVIRGHM+TAYENVPLWHE Sbjct: 241 RGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSENMTGLARVIRGHMLTAYENVPLWHE 300 Query: 301 RDISHSSVERIILPDATMLLNYMLNRFGNIVKNLTVFPDNMKRNMNRTFGVPFSGRILTK 360 RDISHSS ERIILPDAT+ LNYMLNRFGNIVKNLTVFP+NMKRNM+RT G+ +S R+L Sbjct: 301 RDISHSSAERIILPDATIALNYMLNRFGNIVKNLTVFPENMKRNMDRTLGLIYSQRVLLA 360 Query: 361 LIDKGFSREQAYDTVQPRAMQAWEEQTQFRDIVEATPEITAVLSPEEIEDAFNPSWHLKH 420 LIDKG +RE+AYD VQPRAM+AWE+Q F+ +VEA I++ LS EEIED F+ ++H+KH Sbjct: 361 LIDKGMAREEAYDVVQPRAMEAWEKQVAFKSLVEADETISSRLSAEEIEDCFDYNYHIKH 420 Query: 421 VDTIFRKLEL 430 VDTIF +L L Sbjct: 421 VDTIFDRLGL 430 >Q9KF61.1 Q9KF61_BACHD Adenylosuccinate lyase Length = 433 Score = 699 bits (1805), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/430 (76%), Positives = 376/430 (87%) Query: 1 MIERYSRPEMRAIWTEENKFNAWLEVELCACEAWAELGVIPHEDAAKLRKNAKFDIGRIN 60 MIERY+RPEM AIWTEEN++ AWLEVE+ ACEAWAELG IP ED K+R++A FD+ RI Sbjct: 1 MIERYTRPEMGAIWTEENRYQAWLEVEIVACEAWAELGEIPKEDVKKIREHASFDVERIL 60 Query: 61 EIELETRHDVIAFTRAVSESLGAERKWVHYGLTSTDVVDTALGYLLRQANEILEKDIINF 120 EIE ETRHDV+AFTRAVSE+LG ERKWVHYGLTSTDVVDTAL YLL+QANEI+E D++ F Sbjct: 61 EIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTALSYLLKQANEIIEADLVRF 120 Query: 121 IEILKDKALAYKDTPMMGRTHGVHAEPTTFGLKMALWYEEMKRNLERFRHAANGVQFGKI 180 ++ILK+KAL +K T MMGRTHGVHAEPTTFGLK+ALWYEEMKRNLERFR AA GV+ GK+ Sbjct: 121 LDILKEKALEHKYTVMMGRTHGVHAEPTTFGLKLALWYEEMKRNLERFRLAAEGVRVGKL 180 Query: 181 SGAVGTYANIDPFVEEFVCRKLGTSPAPISTQTLQRDRHAEYMAALALVATSLDKFATEI 240 SGAVGTYANIDPFVE++VC KLG APISTQTLQRDRHAEYMA LAL+ATS++KFA EI Sbjct: 181 SGAVGTYANIDPFVEQYVCEKLGLERAPISTQTLQRDRHAEYMATLALIATSIEKFAVEI 240 Query: 241 RALQKSEIREVEEAFAKGQKGSSAMPHKRNPIGCENISGLSRVIRGHMMTAYENVPLWHE 300 R LQKSE REVEE FAKGQKGSSAMPHKRNPIG EN++G++RV+RGHM+ AYENVPLWHE Sbjct: 241 RGLQKSETREVEEYFAKGQKGSSAMPHKRNPIGSENMTGIARVVRGHMLAAYENVPLWHE 300 Query: 301 RDISHSSVERIILPDATMLLNYMLNRFGNIVKNLTVFPDNMKRNMNRTFGVPFSGRILTK 360 RDISHSS ERIILPDAT+ +NYMLNRFGNIVKNLTVFP+NMKRNM RT+G+ +S R+L Sbjct: 301 RDISHSSAERIILPDATIAINYMLNRFGNIVKNLTVFPENMKRNMTRTYGLIYSQRVLLS 360 Query: 361 LIDKGFSREQAYDTVQPRAMQAWEEQTQFRDIVEATPEITAVLSPEEIEDAFNPSWHLKH 420 LIDKG RE+AYD VQP+AM+AWE+ QFR++VE IT+VLSPEEIE F+ + HLKH Sbjct: 361 LIDKGMVREEAYDLVQPKAMEAWEKGVQFRELVEQEERITSVLSPEEIEACFDYNHHLKH 420 Query: 421 VDTIFRKLEL 430 VDTIF +L L Sbjct: 421 VDTIFERLGL 430 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.134 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,541,084,427 Number of extensions: 102176835 Number of successful extensions: 248852 Number of sequences better than 1.0e-05: 3512 Number of HSP's gapped: 245309 Number of HSP's successfully gapped: 3515 Length of query: 431 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 292 Effective length of database: 1,751,175,118 Effective search space: 511343134456 Effective search space used: 511343134456 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)