BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0442.0002.p (246 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KA74.1 B3KA74_9BACI Phosphoribosylaminoimidazole carboxylase, ... 368 e-100 B1D8Y0.1 B1D8Y0_9BACL Phosphoribosylaminoimidazole carboxylase, ... 320 5e-86 Q1AZE7.1 Q1AZE7_RUBXD Phosphoribosylaminoimidazole carboxylase E... 299 1e-79 C0ZK64.1 C0ZK64_BREBN Phosphoribosylaminoimidazole carboxylase A... 288 2e-76 C3AGN7.1 C3AGN7_BACMY Phosphoribosylaminoimidazole carboxylase A... 270 7e-71 >B3KA74.1 B3KA74_9BACI Phosphoribosylaminoimidazole carboxylase, ATPase subunit Length = 395 Score = 368 bits (945), Expect = e-100, Method: Compositional matrix adjust. Identities = 173/246 (70%), Positives = 202/246 (82%), Gaps = 6/246 (2%) Query: 1 VLKTATGGYDGKGQAVIRQPEELEAAFRQVAPGASAGGALPELVLEKFVAFKCEISVVAA 60 VLKTATGGYDGKGQAV+R +ELE+A++++A + ELVLEKFV F CEISV+AA Sbjct: 155 VLKTATGGYDGKGQAVLRSEDELESAYKELAASGT------ELVLEKFVKFACEISVIAA 208 Query: 61 RSASGEVKSFPAAENIHVNNILHLSIVPARVPEEIQRRACELAERIVSGMNAVGLLAVEM 120 R+ SG VKSFP AEN+HVNNILHLSIVPARVP E++R+AC+LAER+ G+ AVGLLAVEM Sbjct: 209 RTPSGIVKSFPPAENVHVNNILHLSIVPARVPSEVKRKACQLAERVAEGLGAVGLLAVEM 268 Query: 121 FVTESGELFVNELAPRPHNSGHYTMDACVTSQFEQHVRAICNLPLGDTSLLTPVVMVNVL 180 FVTE GELFVNELAPRPHNSGHYTM+AC TSQFEQHVRAIC+LPLGDT+LL+PVVMVN+L Sbjct: 269 FVTEEGELFVNELAPRPHNSGHYTMEACSTSQFEQHVRAICDLPLGDTTLLSPVVMVNLL 328 Query: 181 GQHLDGAIQAVCAPDEAGNRLGVAPKLHIYGKAESKTGRKMGHINLLCKDTGDGLSWVEQ 240 GQHL+ A+ D LGV PKLH+YGK+E+K RKMGHINLLC D D L WVE+ Sbjct: 329 GQHLEEAVWRFGEHDALAESLGVVPKLHLYGKSEAKANRKMGHINLLCGDVDDALEWVEK 388 Query: 241 TNLWRN 246 N+WR Sbjct: 389 MNIWRQ 394 >B1D8Y0.1 B1D8Y0_9BACL Phosphoribosylaminoimidazole carboxylase, ATPase subunit Length = 388 Score = 320 bits (821), Expect = 5e-86, Method: Compositional matrix adjust. Identities = 154/245 (62%), Positives = 188/245 (76%), Gaps = 6/245 (2%) Query: 1 VLKTATGGYDGKGQAVIRQPEELEAAFRQVAPGASAGGALPELVLEKFVAFKCEISVVAA 60 VLKTA GGYDGKGQ VIR +E+E A+ + S G ELVLE+F+ F E+SV+AA Sbjct: 149 VLKTAMGGYDGKGQWVIRSFDEIEEAYETL----SRAGV--ELVLEQFIKFDKELSVIAA 202 Query: 61 RSASGEVKSFPAAENIHVNNILHLSIVPARVPEEIQRRACELAERIVSGMNAVGLLAVEM 120 RS GE+K+FPAAENIHV NILHLSIVPAR+ E +Q+ A +LA +I G+ VGL+AVE+ Sbjct: 203 RSPQGEIKAFPAAENIHVENILHLSIVPARIAESVQQEAEKLAIKIAEGLGVVGLIAVEL 262 Query: 121 FVTESGELFVNELAPRPHNSGHYTMDACVTSQFEQHVRAICNLPLGDTSLLTPVVMVNVL 180 F+T GELFVNELAPRPHNSGHYTM+AC TSQFEQHVRA+CNLPLGDT LLTPVVMVNVL Sbjct: 263 FLTADGELFVNELAPRPHNSGHYTMEACRTSQFEQHVRAVCNLPLGDTGLLTPVVMVNVL 322 Query: 181 GQHLDGAIQAVCAPDEAGNRLGVAPKLHIYGKAESKTGRKMGHINLLCKDTGDGLSWVEQ 240 GQH++ + + DEA RL VAPKLH+YGK ++ RKMGH+N+L D L W+E+ Sbjct: 323 GQHVEPLLARMAKHDEAAARLNVAPKLHLYGKKDAVFKRKMGHVNVLAGDVQQALDWIEE 382 Query: 241 TNLWR 245 T +W+ Sbjct: 383 TTIWK 387 >Q1AZE7.1 Q1AZE7_RUBXD Phosphoribosylaminoimidazole carboxylase EC=4.1.1.21 Length = 388 Score = 299 bits (766), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 146/245 (59%), Positives = 183/245 (74%), Gaps = 7/245 (2%) Query: 1 VLKTATGGYDGKGQAVIRQPEELEAAFRQVAPGASAGGALPELVLEKFVAFKCEISVVAA 60 VLKTATGGYDG+GQ VIR +E AA +++ G ELVLE+FV F+ E+SV+AA Sbjct: 145 VLKTATGGYDGRGQRVIRSEDEAPAALSELS------GEGTELVLERFVRFEKELSVIAA 198 Query: 61 RSASGEVKSFPAAENIHVNNILHLSIVPARVPEEIQRRACELAERIVSGMNAVGLLAVEM 120 R+ GEV++FP AEN+HV+NILHLSIVPAR+P E+Q A +A R+ G+ VGL+AVEM Sbjct: 199 RTPGGEVRTFPPAENVHVDNILHLSIVPARIPREVQEEARRMAVRVAEGLGVVGLVAVEM 258 Query: 121 FVTESGELFVNELAPRPHNSGHYTMDACVTSQFEQHVRAICNLPLGDTSLLTPVVMVNVL 180 F L+VNELAPRPHNSGHYT++AC TSQFEQH+RAICNLPLG T LLTP VMVNVL Sbjct: 259 FWAGGDGLYVNELAPRPHNSGHYTIEACATSQFEQHLRAICNLPLGPTDLLTPAVMVNVL 318 Query: 181 GQHLDGAIQAVCAPDEAGNRLGVAPKLHIYGKAESKTGRKMGHINLLCKDTGDGLSWVEQ 240 G+HL+ ++A+ A R G PK+H+YGKAES+ RKMGH+ LL +TG L WVE+ Sbjct: 319 GEHLEPLVRALSEGRIAA-RGGAVPKVHLYGKAESRPKRKMGHVTLLAPETGAALRWVEE 377 Query: 241 TNLWR 245 + LW+ Sbjct: 378 SGLWK 382 >C0ZK64.1 C0ZK64_BREBN Phosphoribosylaminoimidazole carboxylase ATPase subunit EC=4.1.1.21 Length = 387 Score = 288 bits (738), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 141/246 (57%), Positives = 180/246 (73%), Gaps = 13/246 (5%) Query: 1 VLKTATGGYDGKGQAVIRQPEELEAAFRQVAPGASAGGALPELVLEKFVAFKCEISVVAA 60 V+KTATGGYDGKGQ V+R EL A+ + S GA EL++E+FV F+ E+SVVAA Sbjct: 149 VMKTATGGYDGKGQWVLRSEAELAEAYETL----SKAGA--ELIVEQFVPFQMELSVVAA 202 Query: 61 RSASGEVKSFPAAENIHVNNILHLSIVPARVPEEIQRRACELAERIVSGMNAVGLLAVEM 120 R+ +GE+ FP +ENIH NILHLSIVPAR+ E+ RA E+A IV ++ VGL+AVE+ Sbjct: 203 RNPAGELAVFPVSENIHQENILHLSIVPARISAEVAARAEEIARTIVEKLDVVGLIAVEL 262 Query: 121 FVTESGELFVNELAPRPHNSGHYTMDACVTSQFEQHVRAICNLPLGDTSLLTPVVMVNVL 180 F+TE G+L+VNELAPRPHNSGH+TMDACVTSQFEQHVRA+CNLPLG T LL+ VVMVN+L Sbjct: 263 FLTEDGQLYVNELAPRPHNSGHFTMDACVTSQFEQHVRAVCNLPLGSTELLSSVVMVNIL 322 Query: 181 GQHLDGAIQAVCAPDEAGNRLGVAPKLHIYGKAESKTGRKMGHINLLCKDTGDGLSWVEQ 240 G+HL I + ++L KLH+YGKAESK RKMGHIN+L + L+ +++ Sbjct: 323 GEHLQPVIDQI-------DKLPRTAKLHLYGKAESKAKRKMGHINVLAPTVEEALTLIDE 375 Query: 241 TNLWRN 246 +W N Sbjct: 376 LKIWTN 381 >C3AGN7.1 C3AGN7_BACMY Phosphoribosylaminoimidazole carboxylase ATPase subunit Length = 362 Score = 270 bits (691), Expect = 7e-71, Method: Compositional matrix adjust. Identities = 135/244 (55%), Positives = 174/244 (71%), Gaps = 16/244 (6%) Query: 1 VLKTATGGYDGKGQAVIRQPEELEAAFRQVAPGASAGGALPELVLEKFVAFKCEISVVAA 60 VLKT TGGYDGKGQ V+R ++ A R++A A E +LEK+V F+ EISV+ Sbjct: 124 VLKTTTGGYDGKGQVVLRSETDVVRA-RELASQA-------ECILEKWVPFEKEISVIVT 175 Query: 61 RSASGEVKSFPAAENIHVNNILHLSIVPARVPEEIQRRACELAERIVSGMNAVGLLAVEM 120 RS SGE K FP AENIHVNNILH SIVPAR+ EE+ ++ E A+ + + VG LAVEM Sbjct: 176 RSVSGETKVFPVAENIHVNNILHESIVPARISEELSQKGIEYAQVLADELQLVGTLAVEM 235 Query: 121 FVTESGELFVNELAPRPHNSGHYTMDACVTSQFEQHVRAICNLPLGDTSLLTPVVMVNVL 180 F T GE+++NELAPRPHNSGHYT+DAC TSQF QH+RAICNLPLG+T+LL PVVMVN+L Sbjct: 236 FATADGEIYINELAPRPHNSGHYTIDACETSQFGQHIRAICNLPLGETNLLKPVVMVNIL 295 Query: 181 GQHLDGAIQAVCAPDEAGNRLGVAPKLHIYGKAESKTGRKMGHINLLCKDTGDGLSWVEQ 240 G+H++G ++ V NRL LH+YGK E+K RKMGH+N+L ++ D L ++ Sbjct: 296 GEHIEGVLKQV-------NRL-TGCYLHLYGKEEAKLQRKMGHVNILNENVEDALDKAQE 347 Query: 241 TNLW 244 ++W Sbjct: 348 LHIW 351 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.134 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,511,435,239 Number of extensions: 58913183 Number of successful extensions: 135995 Number of sequences better than 1.0e-05: 1822 Number of HSP's gapped: 131675 Number of HSP's successfully gapped: 1822 Length of query: 246 Length of database: 3,060,696,203 Length adjustment: 132 Effective length of query: 114 Effective length of database: 1,817,122,223 Effective search space: 207151933422 Effective search space used: 207151933422 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)