BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0438.0005.p (315 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DHN3.1 B1DHN3_9BACL Transcriptional regulator, LysR family 436 e-120 B3KJ19.1 B3KJ19_9BACI LysR substrate-binding 435 e-120 A4J1K6.1 A4J1K6_DESRM Transcriptional regulator, LysR family 258 6e-67 B8GN50.1 B8GN50_THISH Transcriptional regulator, LysR family 244 6e-63 Q2RHB2.1 Q2RHB2_MOOTA Transcriptional regulator, LysR family 243 2e-62 >B1DHN3.1 B1DHN3_9BACL Transcriptional regulator, LysR family Length = 303 Score = 436 bits (1121), Expect = e-120, Method: Compositional matrix adjust. Identities = 206/285 (72%), Positives = 248/285 (87%) Query: 18 MNFHQLHIFYTVSERGSFSAAAQTLHMTQPAVTMQVQALEDYFGAKLFDRSSKKIMLSEA 77 +NFHQLHIFYTV+ERGSFSAAAQ+LHMTQPAVTMQVQ+LEDYFG KL RS+K+I L+EA Sbjct: 3 LNFHQLHIFYTVAERGSFSAAAQSLHMTQPAVTMQVQSLEDYFGTKLLQRSTKRIDLTEA 62 Query: 78 GRTLLPFALRSIQLMRETDQAMAAFTHMLEGRLLLGASLTIGEYVLPRLLGPFGKAYPHI 137 G+ L+P+A RSI+L+R+TDQAM+AFT L+GRL LGASLTIGEY+LPRLLGPFG+ +P I Sbjct: 63 GKALMPYARRSIELIRDTDQAMSAFTKQLKGRLQLGASLTIGEYILPRLLGPFGQTFPEI 122 Query: 138 SIMMKVMNTSQLLEEIHKHQLNFGLIEAPVSHPDMVIEPVMGDELKLIVPREHPLAGKDE 197 SI MKVMNT+Q++EEI HQL FGLIEAPV+HPDM +E VM DELKLIVP++HPL+ + + Sbjct: 123 SISMKVMNTAQIIEEIINHQLTFGLIEAPVNHPDMQMEAVMSDELKLIVPKDHPLSKRQK 182 Query: 198 VTLAEALEHPFVLREQGSGTRRVMEEQLLAKGLDPGAMRVVMELGSTGAVKSAVEAGLGI 257 V L E ++PFV+REQGSGTR VMEEQL K +DP +++VMELGSTGAVKSAVEAGLG+ Sbjct: 183 VLLDEVADYPFVVREQGSGTRLVMEEQLKRKKIDPADLKIVMELGSTGAVKSAVEAGLGV 242 Query: 258 TIISTSSVKHEVALGLLKIVNIADASFKRQFYAIHLKSTLLPISA 302 + +S SSVKHEVALGLL ++ I D FKRQFY+I+LKSTLLPISA Sbjct: 243 SFVSESSVKHEVALGLLHVIPIEDTRFKRQFYSIYLKSTLLPISA 287 >B3KJ19.1 B3KJ19_9BACI LysR substrate-binding Length = 298 Score = 435 bits (1118), Expect = e-120, Method: Compositional matrix adjust. Identities = 211/286 (73%), Positives = 250/286 (87%), Gaps = 1/286 (0%) Query: 18 MNFHQLHIFYTVSERGSFSAAAQTLHMTQPAVTMQVQALEDYFGAKLFDRSSKKIMLSEA 77 MNFHQLHIFYTV+ERGSFSAAAQ LHM+QPAVTMQVQALE+YFG KL RS+K++ LSEA Sbjct: 1 MNFHQLHIFYTVAERGSFSAAAQALHMSQPAVTMQVQALEEYFGTKLLIRSTKRMELSEA 60 Query: 78 GRTLLPFALRSIQLMRETDQAMAAFTHMLEGRLLLGASLTIGEYVLPRLLGPFGKAYPHI 137 GRTLLPFA RS++L + TD AMAAF++ L+GRL LGASLTIGEYVLPRLLGPFG+ YP I Sbjct: 61 GRTLLPFARRSLELSQATDAAMAAFSNKLQGRLQLGASLTIGEYVLPRLLGPFGREYPDI 120 Query: 138 SIMMKVMNTSQLLEEIHKHQLNFGLIEAPVSHPDMVIEPVMGDELKLIVPREHPLAGK-D 196 SIM+KVMNT+Q+LEEI HQLNFGLIEAPV HPDMV++ VM DELKLIVP HPLA + D Sbjct: 121 SIMLKVMNTTQILEEIASHQLNFGLIEAPVEHPDMVLDAVMEDELKLIVPSSHPLAQRED 180 Query: 197 EVTLAEALEHPFVLREQGSGTRRVMEEQLLAKGLDPGAMRVVMELGSTGAVKSAVEAGLG 256 + L + L +PFVLRE+GSGTR+VME+ LL +G DP +++ VMELGSTGAVKSAVE GLG Sbjct: 181 AIYLKDVLTYPFVLREKGSGTRKVMEDVLLERGHDPESIQTVMELGSTGAVKSAVEEGLG 240 Query: 257 ITIISTSSVKHEVALGLLKIVNIADASFKRQFYAIHLKSTLLPISA 302 IT++STS+VKHE ALGL+K+++IADASFKR FY+IHL+S LLP+SA Sbjct: 241 ITMLSTSTVKHETALGLVKMIDIADASFKRNFYSIHLRSALLPMSA 286 >A4J1K6.1 A4J1K6_DESRM Transcriptional regulator, LysR family Length = 308 Score = 258 bits (658), Expect = 6e-67, Method: Compositional matrix adjust. Identities = 118/275 (42%), Positives = 193/275 (70%) Query: 18 MNFHQLHIFYTVSERGSFSAAAQTLHMTQPAVTMQVQALEDYFGAKLFDRSSKKIMLSEA 77 ++ +Q HIF TV+++ SFS AAQ L+++QPAV+M ++ALED+F KLFDR+++++ ++EA Sbjct: 3 LSLYQFHIFKTVADKKSFSGAAQALYISQPAVSMHIKALEDHFRTKLFDRNTQQVTITEA 62 Query: 78 GRTLLPFALRSIQLMRETDQAMAAFTHMLEGRLLLGASLTIGEYVLPRLLGPFGKAYPHI 137 GR L +A + + L+ + + ++ FT +EG L +GAS T+GEYV+P++LG F K +P + Sbjct: 63 GRILYKYADKILNLIDQAENDISRFTGNIEGPLSIGASFTVGEYVIPKILGTFNKEHPQV 122 Query: 138 SIMMKVMNTSQLLEEIHKHQLNFGLIEAPVSHPDMVIEPVMGDELKLIVPREHPLAGKDE 197 +++V NT Q++ + K +++ GLIE V+ ++V +P + DEL +++P ++PL+ Sbjct: 123 RALLQVTNTEQIVNLVLKQEIDLGLIENQVNKTELVAKPFLQDELIIVIPPDYPLSEHQF 182 Query: 198 VTLAEALEHPFVLREQGSGTRRVMEEQLLAKGLDPGAMRVVMELGSTGAVKSAVEAGLGI 257 +++ + + P V+REQGSGTR++ E +L+ +G+D + +VMELGST AVK AVEAG G Sbjct: 183 ISMEDLVALPLVMREQGSGTRKITEARLIEEGVDLNTLNIVMELGSTEAVKEAVEAGFGT 242 Query: 258 TIISTSSVKHEVALGLLKIVNIADASFKRQFYAIH 292 TIIS +V+ E+ LG L V D S R+FY I+ Sbjct: 243 TIISKWAVQKELKLGTLVPVRFKDISLFRKFYLIY 277 >B8GN50.1 B8GN50_THISH Transcriptional regulator, LysR family Length = 307 Score = 244 bits (624), Expect = 6e-63, Method: Compositional matrix adjust. Identities = 123/283 (43%), Positives = 187/283 (66%), Gaps = 5/283 (1%) Query: 18 MNFHQLHIFYTVSERGSFSAAAQTLHMTQPAVTMQVQALEDYFGAKLFDRSSKKIMLSEA 77 M +L +FYTV+ SF+ AA LHMTQPAVT QV+ LEDYF +LFDR+ ++ L+EA Sbjct: 1 MADRRLQVFYTVARLLSFTKAADALHMTQPAVTFQVRQLEDYFNTRLFDRTHNRVSLTEA 60 Query: 78 GRTLLPFALRSIQLMRETDQAMAAFTHMLEGRLLLGASLTIGEYVLPRLLGPFGKAYPHI 137 GRT+ +A R +L E + ++ T + G L LGAS TI EY+LP LLG F K YP I Sbjct: 61 GRTVYEYAERIFELYSEMENSVRELTGDVSGALTLGASTTIAEYMLPSLLGDFKKKYPEI 120 Query: 138 SIMMKVMNTSQLLEEIHKHQLNFGLIEAPVSHPDMVIEPVMGDELKLIVPREHPLAGKDE 197 +I +KV N+ ++ + + ++ G++E+PVS+ ++++E D+L L+VP +HPLAG+ + Sbjct: 121 NIRLKVSNSEGIVSMVENNIIDLGVVESPVSNRNLLVEVCQQDQLVLVVPPDHPLAGEKK 180 Query: 198 VTLAEALEHPFVLREQGSGTRRVMEEQLLAKGLDPGAMRVVMELGSTGAVKSAVEAGLGI 257 TL + L PF+ RE+GSGTR V+ + + ++G+D A+ V +ELGS A+K AVEAG+G+ Sbjct: 181 ATLDQILLQPFICREEGSGTREVIVDYMASQGVDKNALGVCLELGSPEAIKGAVEAGMGV 240 Query: 258 TIISTSSVKHEVALGLLKIVNIADA-----SFKRQFYAIHLKS 295 +I+S ++V+ E+AL L + +A SF RQ L++ Sbjct: 241 SILSRATVEKELALKRLVAIPLAPPLERPFSFVRQRQKFRLRA 283 >Q2RHB2.1 Q2RHB2_MOOTA Transcriptional regulator, LysR family Length = 297 Score = 243 bits (620), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 117/269 (43%), Positives = 179/269 (66%) Query: 21 HQLHIFYTVSERGSFSAAAQTLHMTQPAVTMQVQALEDYFGAKLFDRSSKKIMLSEAGRT 80 +QL F V+E+ SFS AA+ LH+TQPA+++ +Q+LE+YFG +L DR+++++ L+EAGR Sbjct: 4 NQLLTFKAVAEQKSFSRAARVLHLTQPAISLHIQSLEEYFGTRLLDRNNRQVTLTEAGRV 63 Query: 81 LLPFALRSIQLMRETDQAMAAFTHMLEGRLLLGASLTIGEYVLPRLLGPFGKAYPHISIM 140 L +AL +L E +A+A + ++G L++GA+LTIGEY LP + G F + YP + I Sbjct: 64 LYNYALELSRLYDEVKKALADISGKVKGNLVVGATLTIGEYFLPSIAGEFKRQYPDVEIT 123 Query: 141 MKVMNTSQLLEEIHKHQLNFGLIEAPVSHPDMVIEPVMGDELKLIVPREHPLAGKDEVTL 200 +++ NT +++ +L+ LIE HP+++ E + DEL LI+ EH AG+ E+T Sbjct: 124 LRIANTQEIICRTLDGELDLALIEGQAKHPNLIQEDLFQDELVLIIHPEHRWAGRREITP 183 Query: 201 AEALEHPFVLREQGSGTRRVMEEQLLAKGLDPGAMRVVMELGSTGAVKSAVEAGLGITII 260 E E P +LRE+GSGTR++ E L GL+ ++VVMELGST A+K AVEAGLG+ II Sbjct: 184 EELREEPLILREEGSGTRQITEAGLRKAGLELSTLKVVMELGSTQAIKEAVEAGLGVAII 243 Query: 261 STSSVKHEVALGLLKIVNIADASFKRQFY 289 S ++K E+ LL+ V + F+R F+ Sbjct: 244 SRLAIKKEIRYNLLREVRLQGIDFRRTFH 272 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.323 0.137 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,662,143,791 Number of extensions: 65095794 Number of successful extensions: 214202 Number of sequences better than 1.0e-05: 19738 Number of HSP's gapped: 201516 Number of HSP's successfully gapped: 19739 Length of query: 315 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 180 Effective length of database: 1,788,859,178 Effective search space: 321994652040 Effective search space used: 321994652040 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 131 (55.1 bits)