BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0438.0002.p (172 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A3IDA1.1 A3IDA1_9BACI EAL domain/GGDEF domain protein 186 5e-46 Q0PIC6.1 Q0PIC6_HELMO Signal transduction diguanylate cyclase/ph... 147 3e-34 A1VCR4.1 A1VCR4_DESVV Diguanylate cyclase/phosphodiesterase 146 6e-34 Q72AN3.1 Q72AN3_DESVH EAL domain/GGDEF domain protein 146 6e-34 B0TGE2.1 B0TGE2_HELMI Signal transduction protein, putative 143 6e-33 >A3IDA1.1 A3IDA1_9BACI EAL domain/GGDEF domain protein Length = 293 Score = 186 bits (473), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 90/144 (62%), Positives = 114/144 (79%) Query: 1 VLNDSRHKSGETLSLLQELNLSPERVVFELTERQAVQDYVGFEKVLSHYREQGFRIAVDD 60 VL D ++ SGETL LL+EL + P++VVFELTER AV D+V FE+VLSHYR QG+RIAVDD Sbjct: 131 VLLDKKYHSGETLQLLKELGIKPQQVVFELTERSAVIDFVEFERVLSHYRSQGYRIAVDD 190 Query: 61 AGSGYNSLKTLVYLKPEFIKLDKFLIRGIHSNREQQELLELISEYASRSATRVIAEGIET 120 GSGYNSLKTL+YLKPEFIKLD+ LI+ I EQQ+L+ L+ +YA ++ T++IAEGIE Sbjct: 191 VGSGYNSLKTLIYLKPEFIKLDRSLIQSIDQISEQQQLVTLLMKYAEQAKTKIIAEGIER 250 Query: 121 EEELLYLQMASIEFGQGYALGRPG 144 +EEL YL I + QGYA+G+P Sbjct: 251 QEELEYLHRIGIHYAQGYAIGKPA 274 >Q0PIC6.1 Q0PIC6_HELMO Signal transduction diguanylate cyclase/phosphodiesterase Length = 786 Score = 147 bits (372), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 71/143 (49%), Positives = 96/143 (67%) Query: 1 VLNDSRHKSGETLSLLQELNLSPERVVFELTERQAVQDYVGFEKVLSHYREQGFRIAVDD 60 V+ D G T L+ LSP VVFE+TER A+QD+ GF K+L HYR+QGFR+AVDD Sbjct: 292 VVKDPLFAKGYTRGLMALYGLSPYNVVFEITERTAIQDFTGFRKILQHYRDQGFRVAVDD 351 Query: 61 AGSGYNSLKTLVYLKPEFIKLDKFLIRGIHSNREQQELLELISEYASRSATRVIAEGIET 120 AG+GY+SL+ + L+P+FIK+D LIR I ++ +Q LLE + + +++AEGIET Sbjct: 352 AGAGYSSLQAIAELQPDFIKIDMSLIRDIDASPVKQALLETFVTFGEKIGAKIVAEGIET 411 Query: 121 EEELLYLQMASIEFGQGYALGRP 143 E+EL L + GQGY LGRP Sbjct: 412 EKELRLLAQMGVHIGQGYYLGRP 434 >A1VCR4.1 A1VCR4_DESVV Diguanylate cyclase/phosphodiesterase Length = 797 Score = 146 bits (369), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 72/145 (49%), Positives = 93/145 (64%) Query: 1 VLNDSRHKSGETLSLLQELNLSPERVVFELTERQAVQDYVGFEKVLSHYREQGFRIAVDD 60 L+D G TL L++ L PE VVFE+TER A++D F K L HYR QGF IA+DD Sbjct: 294 TLSDPEFTPGSTLRALRDTGLRPEDVVFEITERHAIKDLTTFYKTLEHYRGQGFGIAIDD 353 Query: 61 AGSGYNSLKTLVYLKPEFIKLDKFLIRGIHSNREQQELLELISEYASRSATRVIAEGIET 120 AG+GY+ L ++ LKP+FIK+D L+RGIH + +Q L+E ++A + RVIAEGIE Sbjct: 354 AGTGYSGLASIAELKPDFIKIDMSLVRGIHRDPVRQALIETFIDFAEKIGARVIAEGIEC 413 Query: 121 EEELLYLQMASIEFGQGYALGRPGY 145 EE L +GQGY LGRP Y Sbjct: 414 REEASILLRMGAHYGQGYYLGRPSY 438 >Q72AN3.1 Q72AN3_DESVH EAL domain/GGDEF domain protein Length = 797 Score = 146 bits (369), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 72/145 (49%), Positives = 93/145 (64%) Query: 1 VLNDSRHKSGETLSLLQELNLSPERVVFELTERQAVQDYVGFEKVLSHYREQGFRIAVDD 60 L+D G TL L++ L PE VVFE+TER A++D F K L HYR QGF IA+DD Sbjct: 294 TLSDPEFTPGSTLRALRDTGLRPEDVVFEITERHAIKDLTTFYKTLEHYRGQGFGIAIDD 353 Query: 61 AGSGYNSLKTLVYLKPEFIKLDKFLIRGIHSNREQQELLELISEYASRSATRVIAEGIET 120 AG+GY+ L ++ LKP+FIK+D L+RGIH + +Q L+E ++A + RVIAEGIE Sbjct: 354 AGTGYSGLASIAELKPDFIKIDMSLVRGIHRDPVRQALIETFIDFAEKIGARVIAEGIEC 413 Query: 121 EEELLYLQMASIEFGQGYALGRPGY 145 EE L +GQGY LGRP Y Sbjct: 414 REEASILLRMGAHYGQGYYLGRPSY 438 >B0TGE2.1 B0TGE2_HELMI Signal transduction protein, putative Length = 780 Score = 143 bits (360), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 65/143 (45%), Positives = 95/143 (66%) Query: 1 VLNDSRHKSGETLSLLQELNLSPERVVFELTERQAVQDYVGFEKVLSHYREQGFRIAVDD 60 V+ D G T L+ E L P +VFE+TER A+ D+ F K L HYREQGFR+AVDD Sbjct: 283 VVKDPEFAQGNTRRLIAEHGLRPHNIVFEITERTAIDDFGSFRKTLKHYREQGFRVAVDD 342 Query: 61 AGSGYNSLKTLVYLKPEFIKLDKFLIRGIHSNREQQELLELISEYASRSATRVIAEGIET 120 AG+GY+SL+ + L+P+FIK+D L+R I ++ +Q L+E + + +++AEGIET Sbjct: 343 AGAGYSSLQAIAELQPDFIKIDMSLVRDIDTSSIKQALMETFVTFGRKIGAKIVAEGIET 402 Query: 121 EEELLYLQMASIEFGQGYALGRP 143 E+EL +L ++ GQG+ +GRP Sbjct: 403 EKELRFLSQIGVDIGQGFFIGRP 425 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.315 0.135 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,022,673,320 Number of extensions: 40090564 Number of successful extensions: 92299 Number of sequences better than 1.0e-05: 7979 Number of HSP's gapped: 91058 Number of HSP's successfully gapped: 7979 Length of query: 172 Length of database: 3,060,696,203 Length adjustment: 126 Effective length of query: 46 Effective length of database: 1,873,648,313 Effective search space: 86187822398 Effective search space used: 86187822398 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 126 (53.1 bits)