BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0437.0035.p (202 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1KTN5.1 B1KTN5_CLOBM Putative regulatory protein BetI 186 8e-46 B1IEB0.1 B1IEB0_CLOBK Transcriptional regulator, TetR family 184 6e-45 C2KP74.1 C2KP74_9ACTO TetR family transcriptional regulator 80 7e-14 C2BVA7.1 C2BVA7_9ACTO TetR family transcriptional regulator 79 2e-13 Q8RG45.1 Q8RG45_FUSNN Regulatory protein betI 79 2e-13 >B1KTN5.1 B1KTN5_CLOBM Putative regulatory protein BetI Length = 203 Score = 186 bits (473), Expect = 8e-46, Method: Compositional matrix adjust. Identities = 93/201 (46%), Positives = 135/201 (67%) Query: 2 QAKKDEVKRDIESAALKVFFRKGFADAKMNDIADEIQISVGNIYTYFKNKQELFYAVVPP 61 Q KKDE+K+D+ESAALK+F +KG+ D KM+ IA ISVGNIY YFKNK++LFY+VVP Sbjct: 3 QIKKDEIKKDVESAALKIFSQKGYLDTKMSHIAKTANISVGNIYIYFKNKEDLFYSVVPE 62 Query: 62 SLVDYLKNVLVESIRLDNQTFFDRAGSDKQSAIVQEQMNLLTQYSMQIVIIFEKNKGTVY 121 L+ +L++ LV+SI + N+ FD+ ++ +E MN+L Y M +IIFEK+KGT Y Sbjct: 63 KLMIFLRDFLVKSIHIFNKKQFDKLANEDDYFFSKECMNILIDYRMHFLIIFEKSKGTKY 122 Query: 122 SNAKNELIELMIETKKPFLKDHYKRYEIGTEEXXXXXXXXXXXXXXXXXDLLKREMGADS 181 NAK ELI+ ++E KK +L++++KRY + E+ D+LK +M Sbjct: 123 ENAKEELIDSLLEAKKIYLRNNHKRYNLSVEDGIRVTRIILNNLINMVLDVLKEDMSESD 182 Query: 182 RRRIFEALSLYWLHGLTGINE 202 R+ IF AL++Y L+G+TG+NE Sbjct: 183 RKSIFRALNVYRLYGITGLNE 203 >B1IEB0.1 B1IEB0_CLOBK Transcriptional regulator, TetR family Length = 203 Score = 184 bits (466), Expect = 6e-45, Method: Compositional matrix adjust. Identities = 91/201 (45%), Positives = 135/201 (67%) Query: 2 QAKKDEVKRDIESAALKVFFRKGFADAKMNDIADEIQISVGNIYTYFKNKQELFYAVVPP 61 Q KKDE+K+D+E+AALK+F ++G+ D KM+ IA ISVGNIY YFKNK++LFY+VVP Sbjct: 3 QIKKDEIKKDVENAALKIFSQEGYLDTKMSHIAKTANISVGNIYIYFKNKEDLFYSVVPE 62 Query: 62 SLVDYLKNVLVESIRLDNQTFFDRAGSDKQSAIVQEQMNLLTQYSMQIVIIFEKNKGTVY 121 L+ +L++ LV+SI + N+ FD+ ++ +E MN+L Y M +IIFEK+KGT Y Sbjct: 63 KLMIFLRDFLVKSIHIFNKKQFDKLANEDDYFFSEECMNILIDYRMHFLIIFEKSKGTKY 122 Query: 122 SNAKNELIELMIETKKPFLKDHYKRYEIGTEEXXXXXXXXXXXXXXXXXDLLKREMGADS 181 NAK ELI+ ++E KK +L++++KRY + E+ D+LK +M Sbjct: 123 ENAKEELIDSLLEAKKIYLRNNHKRYNLSVEDGIKVTRIILNNFINMVLDVLKEDMSESD 182 Query: 182 RRRIFEALSLYWLHGLTGINE 202 R+ IF AL++Y L+G+TG+NE Sbjct: 183 RKSIFRALNVYRLYGITGLNE 203 >C2KP74.1 C2KP74_9ACTO TetR family transcriptional regulator Length = 190 Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 41/129 (31%), Positives = 74/129 (57%), Gaps = 6/129 (4%) Query: 2 QAKKDEVKRDIESAALKVFFRKGFADAKMNDIADEIQISVGNIYTYFKNKQELFYAVVPP 61 Q K+EV+ + +AA ++F +GF+ A++ DIAD +S G +Y+YFKNK+ELF AV+ P Sbjct: 3 QVLKEEVRESLVAAASQIFMERGFSGARLTDIADTAGVSTGLVYSYFKNKEELFQAVIAP 62 Query: 62 SLVDYLKNVLVESIRLDNQTFFDRAGSDKQSAIVQEQMNLLTQYSMQIVIIFEKNKGTVY 121 D+ E+I + + +K E + + +Y + VI+ +K+ GT Y Sbjct: 63 LPPDF------EAIAQAEEALETGSPLEKYQTAAAEYIENILKYHREFVILMDKSHGTPY 116 Query: 122 SNAKNELIE 130 ++ K+ +++ Sbjct: 117 ADTKSRMVQ 125 >C2BVA7.1 C2BVA7_9ACTO TetR family transcriptional regulator Length = 199 Score = 79.3 bits (194), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 44/128 (34%), Positives = 71/128 (55%), Gaps = 6/128 (4%) Query: 2 QAKKDEVKRDIESAALKVFFRKGFADAKMNDIADEIQISVGNIYTYFKNKQELFYAVVPP 61 Q K+EV+ + +AA +VFF KGFA A++ DIA +S G Y+YFKNK+ LF V+ P Sbjct: 12 QVLKEEVRDGLVAAASEVFFAKGFARARLADIASRAGVSTGLAYSYFKNKEALFQTVISP 71 Query: 62 SLVDYLKNVLVESIRLDNQTFFDRAGSDKQSAIVQEQMNLLTQYSMQIVIIFEKNKGTVY 121 +D+ E+I + + + DK + + + ++ + VI+ +K++GT Y Sbjct: 72 LPLDF------EAIAHEEEAIEKGSPFDKYKEVAAGYIETILRHHREFVILIDKSQGTAY 125 Query: 122 SNAKNELI 129 AK LI Sbjct: 126 EGAKESLI 133 >Q8RG45.1 Q8RG45_FUSNN Regulatory protein betI Length = 189 Score = 79.0 bits (193), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 51/145 (35%), Positives = 83/145 (57%), Gaps = 15/145 (10%) Query: 2 QAKKDEVKRDIESAALKVFFRKGFADAKMNDIADEIQISVGNIYTYFKNKQELFYAVVPP 61 Q K+E+K I AA K+F+ KGF KM DI++E +I VG +YTY+KNK+ELF +V P Sbjct: 3 QILKEEIKNRIYKAASKIFYEKGFLKTKMKDISEEAKIPVGLVYTYYKNKEELFDEIVNP 62 Query: 62 SLVDYLKNVLVESIRLDNQTFFDRAGSDKQSAIVQEQMNLLTQYSMQIVIIFEKNKGTVY 121 + Y N+ +E + + +R + + +++ LL Q+ +VI+ +K +GT + Sbjct: 63 --IYYYLNLAIEKEEKEEGSALERFKATGEEYVLK----LLNQHK-SLVILMDKAQGTKH 115 Query: 122 SNAKNELIELMIETKKPFLKDHYKR 146 NAK I++ L++H KR Sbjct: 116 ENAKQVFIKI--------LENHIKR 132 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.135 0.373 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 954,002,205 Number of extensions: 32602763 Number of successful extensions: 106495 Number of sequences better than 1.0e-05: 95 Number of HSP's gapped: 106638 Number of HSP's successfully gapped: 95 Length of query: 202 Length of database: 3,060,696,203 Length adjustment: 129 Effective length of query: 73 Effective length of database: 1,845,385,268 Effective search space: 134713124564 Effective search space used: 134713124564 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 128 (53.9 bits)