BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0437.0027.p (588 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1D784.1 B1D784_9BACL Histidine kinase internal region 768 0.0 B3K644.1 B3K644_9BACI Histidine kinase internal region 449 e-124 A9U830.1 A9U830_PHYPA Predicted protein (Fragment) 245 1e-62 C0C1J1.1 C0C1J1_9CLOT Putative uncharacterized protein 208 1e-51 B0K338.1 B0K338_THEPX Histidine kinase internal region 204 2e-50 >B1D784.1 B1D784_9BACL Histidine kinase internal region Length = 591 Score = 768 bits (1982), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/587 (63%), Positives = 461/587 (78%), Gaps = 2/587 (0%) Query: 3 MTFRYRLLASYIFLITIPLLVLGTLFYRTSLQIITEQAQKNVYELVKKNNEVMDTKLRIV 62 MTFR RLL SY+ LI +PLLVL TLFY +SL+++TEQAQ NV+++V KNN+V+DTKL IV Sbjct: 1 MTFRLRLLLSYLTLIALPLLVLSTLFYNSSLKVVTEQAQNNVHDVVMKNNDVIDTKLGIV 60 Query: 63 DQNSMSLFLDKDLFRIFNQLDPANEAGLFEADRQVTAILGKYFSQNQDIYAYQLWTSYFT 122 DQNS SLF+DKDLF+IFN L+PA E L ADRQVTAIL KYFSQN D+YA QLWTSY+T Sbjct: 61 DQNSRSLFVDKDLFQIFNNLNPAKEEELVAADRQVTAILSKYFSQNSDVYAAQLWTSYYT 120 Query: 123 FGQTL--PQGDPTQSDIYEMALQAGGKLVWVPTYDFVSMFHQPYLQSGNLEFRYLFSATR 180 FG T+ P GDP QS IY+ A++AGGK+VW PTYDF+ M+ Q +LQ G +++RYLFSATR Sbjct: 121 FGSTMLMPLGDPVQSAIYKEAVKAGGKMVWYPTYDFIKMYDQHWLQDGTIDYRYLFSATR 180 Query: 181 VLDFTYLGNTKLEKMNARAERPVLAISFKSEVLKSLYADSISGSARYMVLDPHDKVVASS 240 +L+F+++ ++ L K+ ERPVLAISFKS V+ L+ SI + YMVLDP + VVASS Sbjct: 181 LLNFSHMEDSTLVKLKPEVERPVLAISFKSTVMDELFEKSIPAGSSYMVLDPDNIVVASS 240 Query: 241 EPGAVARTSKEAWLDELKQERSGARRMTLDGEAVIVCFDRSEVTGWMSVVWIPEAGLLSS 300 + V + E W+++ +++ SG+ R+ L+G IV F RSEVTGWMS+V P++ L+SS Sbjct: 241 DQSQVTKRFDEDWMNDFREQGSGSERIKLNGHNQIVSFARSEVTGWMSIVITPQSVLVSS 300 Query: 301 FVPVIRTSITVLAVVXXXXXXXXXXXXXXKITKPIKRLLSAMRSVGEGDFQTRVEVVTND 360 VPV+RTS V A+ +IT PIK+L+SAMRSVGEGDF+ RV+V D Sbjct: 301 LVPVLRTSTIVSAIALSAVALLFAYFIISRITGPIKKLMSAMRSVGEGDFEARVDVDRKD 360 Query: 361 EFGMLTKRFNRMNDRIHLLVTENYEIKLKEKEAEIQALTMQMHPHFLYNTLNVMNWTAIE 420 EFG+L++RFNRMNDRI +LV ENYEIKLKEKEAEIQAL MQM+PHFLYNTLN+MNWTA+E Sbjct: 361 EFGLLSQRFNRMNDRIAMLVKENYEIKLKEKEAEIQALNMQMNPHFLYNTLNIMNWTALE 420 Query: 421 NGQQELSRMLVCLSNMLHYTSRKTWDAVHLSEEMNWMDNYFYIMSIRFEDKFTVEYAIDP 480 N Q ELS+MLVCLSNMLHYTSRK W+AVHLSEE+ WM NYF+IMS RFE KFTV Y I+P Sbjct: 421 NRQTELSKMLVCLSNMLHYTSRKDWEAVHLSEELEWMRNYFFIMSARFEGKFTVAYEIEP 480 Query: 481 QLYEYDVPRLLFQPFVENAILHGFNQTESGGMIRIRGWIAEGTRFYEVADNGRGMSQETV 540 LYE +PRLLFQPFVENAILHGF+ E GG I IRGWI + +R++EV DNGRG+S+E + Sbjct: 481 VLYENKLPRLLFQPFVENAILHGFSGVEEGGQITIRGWIEDDSRYFEVRDNGRGISKEGI 540 Query: 541 QAILYQKSSSVGIKNTIDRIQIAYGTLYGVSIVSAPGEGTRVVITLP 587 AILY++S+S+GIKNTI RI++AYG YG+ I SAPG+GT +VI LP Sbjct: 541 DAILYKESASIGIKNTISRIRMAYGDEYGIRIHSAPGKGTSIVIHLP 587 >B3K644.1 B3K644_9BACI Histidine kinase internal region Length = 598 Score = 449 bits (1156), Expect = e-124, Method: Compositional matrix adjust. Identities = 232/591 (39%), Positives = 355/591 (60%), Gaps = 8/591 (1%) Query: 3 MTFRYRLLASYIFLITIPLLVLGTLFYRTSLQIITEQAQKNVYELVKKNNEVMDTKLRIV 62 M + +L+ SYI LIT+PL+ LGT + S ++ + A+ NV E+V+KNN+++D +L+I+ Sbjct: 1 MRLKNKLILSYIILITLPLVTLGTGSFYASKNMMLKLARDNVTEIVQKNNQIIDERLKII 60 Query: 63 DQNSMSLFLDKDLFRIFNQLDPANEAGLFEADRQVTAILGKYFSQNQDIYAYQLWTSYFT 122 NS+SL ++ DLF+IF+ PA ++ L ++QVT IL +YFSQ++D+Y+ +L T F Sbjct: 61 QDNSLSLMVECDLFQIFDGAAPA-QSKLLATNKQVTEILNRYFSQSRDLYSVELVTRAFV 119 Query: 123 FG----QTLPQGDPTQSDIYEMALQAGGKLVWVPTYDFVSMFHQPYLQSGNLEFRYLFSA 178 +G T P S++Y A + G+L WVPTYD+ M P L ++E+RYLFSA Sbjct: 120 YGSKARNTYPPDHFYDSELYRQASEQKGRLAWVPTYDYSLMHQLPDLAGADIEYRYLFSA 179 Query: 179 TRVLDFTYLGNTKLEKMNARAERPVLAISFKSEVLKSLYADSI--SGSARYMVLDPHDKV 236 R ++ + + N + + A +E+PVL ++F+ + L+ +SI GS ++V + Sbjct: 180 VRQMNPSCVRNDAIVRARAGSEKPVLVMNFRDGLYADLFRNSIPIEGSV-FLVAGADGTI 238 Query: 237 VASSEPGAVARTSKEAWLDELKQERSGARRMTLDGEAVIVCFDRSEVTGWMSVVWIPEAG 296 ++ + V R WL E++ SGA + +DG+ I C+ S +TGW SVV IP Sbjct: 239 ISHANAEFVGRKPSFPWLAEVQNRGSGASFVMVDGKRTIACYTTSAITGWTSVVLIPPGA 298 Query: 297 LLSSFVPVIRTSITVLAVVXXXXXXXXXXXXXXKITKPIKRLLSAMRSVGEGDFQTRVEV 356 L I I L +IT P+++LL A++ VG GDF +++V Sbjct: 299 LTKDIGQTITFFILTLGASLLLLSLFFAYLISMRITSPVRKLLLAIKRVGGGDFNAKIKV 358 Query: 357 VTNDEFGMLTKRFNRMNDRIHLLVTENYEIKLKEKEAEIQALTMQMHPHFLYNTLNVMNW 416 DE G + +FN MN+++ L+ ENY KL+E+E EI AL +Q++PHFLYNTLN++NW Sbjct: 359 EGKDELGHVLMKFNSMNEKVRQLIEENYVAKLRERETEILALGIQLNPHFLYNTLNIINW 418 Query: 417 TAIENGQQELSRMLVCLSNMLHYTSRKTWDAVHLSEEMNWMDNYFYIMSIRFEDKFTVEY 476 A+ ++++SRMLV LS MLHYT+ D++ LSE++ W+ +Y IMS RFE +F V++ Sbjct: 419 MAVYGEKEQVSRMLVSLSRMLHYTTDNRKDSMPLSEDIGWLQDYIVIMSNRFEHRFRVDF 478 Query: 477 AIDPQLYEYDVPRLLFQPFVENAILHGFNQTESGGMIRIRGWIAEGTRFYEVADNGRGMS 536 I+P+L + VP+L QP VENAI+HGF ESGG+I I G + V DNG G Sbjct: 479 DIEPELMKARVPKLFLQPLVENAIIHGFRDMESGGLITIYGRSLGDDIEFCVEDNGCGFE 538 Query: 537 QETVQAILYQKSSSVGIKNTIDRIQIAYGTLYGVSIVSAPGEGTRVVITLP 587 E ++ L + +S +GI N RI++ YG YG+ I S P GTRV + +P Sbjct: 539 PERLKEALAENASHIGIHNVDKRIKLLYGDRYGIGIESVPELGTRVKLVIP 589 >A9U830.1 A9U830_PHYPA Predicted protein (Fragment) Length = 367 Score = 245 bits (625), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 133/367 (36%), Positives = 214/367 (58%), Gaps = 8/367 (2%) Query: 94 DRQVTAILGKYFSQNQDIYAYQLWTSYFTFGQT-----LPQGDPTQSDIYEMALQAGGKL 148 +++V+ + YF + +Y+ L TSY G T +P Q+ +Y+ A+QA G + Sbjct: 2 EKKVSRAMNTYFPDLKHMYSIHLITSYSDIGPTGATTFIPYEGFNQTALYQAAVQADGGM 61 Query: 149 VWVPTYDFVSMFHQPYLQSGNLEFRYLFSATRVLDFTYLGNTKLEKMNARAERPVLAISF 208 WVPT+ F MFH+ E L + R+L + N ++ ++ AE PVL I++ Sbjct: 62 AWVPTFSFGDMFHRDAGSPVPSENVQLLAGVRLLKLFRINNGEVIELQGAAELPVLVITY 121 Query: 209 KSEVLKSLYADSI-SGSARYMVLDPHDKVVASSEPGAVARTSKEAWLDELKQERSGARRM 267 + + +S +A + S A + ++ + VA S+ T + L + + +SG + Sbjct: 122 QPDYYRSRFASVLPSTGASFFIMSRDGQRVADSQ--EKDSTMDDTSLKRMAEMKSGTLTI 179 Query: 268 TLDGEAVIVCFDRSEVTGWMSVVWIPEAGLLSSFVPVIRTSITVLAVVXXXXXXXXXXXX 327 T +G+ +IVCFD S+VTGW+S V I L S+F+P +++ L ++ Sbjct: 180 TRNGKPLIVCFDTSDVTGWISGVMISPEALGSAFLPEVKSYTFYLTLILLLLSLLLAFFL 239 Query: 328 XXKITKPIKRLLSAMRSVGEGDFQTRVEVVTNDEFGMLTKRFNRMNDRIHLLVTENYEIK 387 ITKPI++LL A++ GEG+F TR+ V + +E G+L ++N+MN +I+ L+ ENY++K Sbjct: 240 ANSITKPIQQLLRAIKKTGEGEFDTRIPVKSYNEMGLLIHKYNQMNVKINNLIEENYKVK 299 Query: 388 LKEKEAEIQALTMQMHPHFLYNTLNVMNWTAIENGQQELSRMLVCLSNMLHYTSRKTWDA 447 L+EKE +I +L +Q++PHFLYNTLN+MNWTA+EN Q ELS M+V LS+ML YTS D Sbjct: 300 LREKETQIMSLNIQLNPHFLYNTLNIMNWTALENEQNELSAMIVSLSSMLQYTSASNQDI 359 Query: 448 VHLSEEM 454 L E++ Sbjct: 360 GDLEEDL 366 >C0C1J1.1 C0C1J1_9CLOT Putative uncharacterized protein Length = 601 Score = 208 bits (530), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 163/612 (26%), Positives = 282/612 (46%), Gaps = 47/612 (7%) Query: 3 MTFRYRLLASYIFLITIPLLVLGTLFYRTSLQIITEQAQKNVYELVKKNNEVMDTKLRIV 62 + + +L +I +I + + +LG S Q I Q ++ E + + E ++ +++ V Sbjct: 9 LKMKNKLFIGFILVIAVLVSLLGYFSMTFSEQSIRTQMLDSIQETMNQMGENIEGEIQKV 68 Query: 63 DQNSMSLFLDKDLFRIFNQLDPANEAGLFEADRQVTAILGK----YFSQNQDIYAYQLWT 118 S + L+++L + + P + D+ + IL + YFS +D++ Sbjct: 69 LDVSAQVCLNEELCTVLQEEKPGTIEEYYSKDKTMRQILNESYAAYFSV-EDVFVCSYNG 127 Query: 119 SYFTFGQT----LPQGDPTQSDIYEMALQAGGKLVWVPTYDFVSMFHQPYLQSGNLEFRY 174 S + + D T++ + Q+G + + YD S Y+ +G E + Sbjct: 128 SVYGSDKNKLSLTADYDFTRTGWFADMKQSGAGVSILSQYDSSS-----YISTG--EPQK 180 Query: 175 LFSATRVLDFTYLGNTKLEKMNARAERPVLAISFKSEVLKSLYADSISGS-ARYMVLDPH 233 LFS + K+ + E L + S++L ++ S + +++D + Sbjct: 181 LFSIVK----------KIYNYRSGKEIGCLIVHMNSDILGNVLQSVNSNEYQQCLIIDNN 230 Query: 234 DKVVASSEPGAVARTSKEAWLDELKQERSGARRMTLDGEAVIVCFDRSEVTGWMSVVWIP 293 K++ + + +EA + EL +G M E + F S VTGW SV+ + Sbjct: 231 KKIIYHPDSDYIGTQYREARVSELLTMENG--YMESLSEKGYLVFSTSAVTGW-SVISVV 287 Query: 294 EAGLLSSFVPVIRTSITVLAVVXXXXXXXXXXXXXXKITKPIKRLLSAMRSVGEGDFQTR 353 + + + +R + + AV I+ P+ RL M VGEGDF R Sbjct: 288 DNKYIMDSINRLRLFLILTAVFCVVLSVYFASYISKTISDPVARLQRKMYQVGEGDFDIR 347 Query: 354 VEVVTNDEFGMLTKRFNRMNDRIHLLVTENYEIKLKEKEAEIQALTMQMHPHFLYNTLNV 413 +DE G LT F++M +R L+ Y+ ++ +KEAE+ AL Q++PHFLYNTL Sbjct: 348 AATGASDEIGQLTLSFDKMVERTKQLIENVYQSEIYQKEAELNALQAQINPHFLYNTLQT 407 Query: 414 MNWTAIENGQQELSRMLVCLSNMLHYTSRKTWDAVHLSEEMNWMDNYFYIMSIRFEDKFT 473 ++ A E G E+S LS + Y+ + + VH+ +E+ ++NY I +RF K Sbjct: 408 IDMMAEEEGADEISDACQALSKIFRYSINRGQEFVHVQDEIVHIENYMLIQKLRFGGKLE 467 Query: 474 VEYAIDPQLYEYDVPRLLFQPFVENAILHGFNQTESGGMIRIRGWIAEGTRFYEVADNGR 533 V Y I + E + +LL QP VENA++HG + IR + E + EV DNG Sbjct: 468 VRYDIQNECRELYIVKLLIQPMVENAVVHGMENVLDKCYVTIRVYRKEDCLYAEVEDNGT 527 Query: 534 GMS----------------QETVQAILYQKSS-SVGIKNTIDRIQIAYGTLYGVSIVSAP 576 G++ Q+ V + Y K+ S+G++NT RI++ +G YG++I S Sbjct: 528 GIAPGQLMELNEKLARSAEQKMVHEVDYVKNHRSIGLENTNARIKLYFGQEYGITITSEE 587 Query: 577 GEGTRVVITLPV 588 G GT+V I LPV Sbjct: 588 GTGTKVCIKLPV 599 >B0K338.1 B0K338_THEPX Histidine kinase internal region Length = 567 Score = 204 bits (519), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 155/575 (26%), Positives = 279/575 (48%), Gaps = 61/575 (10%) Query: 8 RLLASYIFLITIPLLVLGTLFYRTSLQIITEQAQKNVYELVKKNNEVMDTKLRIVDQNSM 67 ++L SYI +I IPL+++ + + + I E+ +K ++ + + N+ + L + + Sbjct: 5 KILLSYILIIVIPLIMVAAITGNITSRYINEEVKKTTFQTLNQANKNISKMLENMKNAIL 64 Query: 68 SLFLDKDLFRIFNQLDPANEAG--LFEADRQVTAILGKY-----FSQN-QDIYAYQLWTS 119 + ++K+L Q + + G F+ +R+VTAI F++N I + L + Sbjct: 65 YVSMNKEL-----QYNLSRNGGETPFQINREVTAIRNSILYPGIFNENYSSIEIFALHKN 119 Query: 120 YFTFGQTLPQGDPTQSDI------YEMALQAGGKLVWVPTYDFVSMFHQPYLQSGNLEFR 173 + L Q D S + Y+ +Q G+L W DF + Sbjct: 120 QYPM--RLEQNDVMSSKVVENKEWYKKTIQLNGRLYWYINDDF---------------GK 162 Query: 174 YLFSATR-VLDFTYLGNTKLEKMNARAERPVLAISFKSEVLK--SLYAD-SISGSARYMV 229 + S +R V D +P+ IS ++ K S+ +D + + + + Sbjct: 163 QMISVSRLVFDIKNFA------------KPIAVISVDMDMSKVASVVSDIHLGKTGKVYL 210 Query: 230 LDPHDKVVASSEPGAVARTSKEAWLDELKQERSGARRMTLDGEAVIVCFDRSEVTGWMSV 289 +D K++ S + + R + +L SG+ +T++G ++V ++ GW V Sbjct: 211 VDDKGKLIYSEDKSFLYR-----YTTKLYNSSSGSDFITINGNKIMVIYNTLPQNGWKLV 265 Query: 290 VWIPEAGLLSSFVPVIRTSITVLAVVXXXXXXXXXXXXXXKITKPIKRLLSAMRSVGEGD 349 + A L + +IR I + A++ I++PI +L + M+ V +G+ Sbjct: 266 GMVSMAEL-NEKAEMIRNFIYLTALLSLVIAALISLYFSYSISQPIIKLATEMKKVEKGN 324 Query: 350 FQTRVEVVTNDEFGMLTKRFNRMNDRIHLLVTENYEIKLKEKEAEIQALTMQMHPHFLYN 409 F VE + E G+L FN M +RI+ L+ E Y K+KEK+AE++AL Q++PHFLYN Sbjct: 325 FNISVEENWDGEIGVLYSSFNYMIERINELIHEVYLSKIKEKDAELKALQAQINPHFLYN 384 Query: 410 TLNVMNWTAIENGQQELSRMLVCLSNMLHYTSRKTWDAVHLSEEMNWMDNYFYIMSIRFE 469 TL+ +NW A+++ E+S+++ L+++L Y+ K D + E+ +++Y I IRF+ Sbjct: 385 TLDTVNWLAVKHNVPEISKIVNSLASILRYSINKGNDVTTVENELKHVESYITIQKIRFK 444 Query: 470 DKFTVEYAIDPQLYEYDVPRLLFQPFVENAILHGFNQTESGGMIRIRGWIAEGTRFYEVA 529 DKF V + ID ++ Y +L+ QP VENAI+HG E G I I G++ +EV Sbjct: 445 DKFEVSFNIDKRVLHYKTIKLILQPLVENAIIHGIETYEGKGKILINGYLDGEKIVFEVI 504 Query: 530 DNGRGMSQETVQAIL---YQKSSSVGIKNTIDRIQ 561 +NG + + V +L S GI+N +RI+ Sbjct: 505 NNGNPIDLDLVNKLLDSPADDKDSYGIQNVNERIK 539 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.135 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,265,642,180 Number of extensions: 129614441 Number of successful extensions: 363961 Number of sequences better than 1.0e-05: 2301 Number of HSP's gapped: 361396 Number of HSP's successfully gapped: 2301 Length of query: 588 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 446 Effective length of database: 1,722,912,073 Effective search space: 768418784558 Effective search space used: 768418784558 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 134 (56.2 bits)