BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0437.0011.p (346 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B8I4M7.1 B8I4M7_CLOCE Alcohol dehydrogenase GroES domain protein 507 e-142 C0C0V8.1 C0C0V8_9CLOT Putative uncharacterized protein 491 e-137 A6TKU9.1 A6TKU9_ALKMQ Alcohol dehydrogenase, zinc-binding domain... 440 e-121 C0CQL1.1 C0CQL1_9FIRM Putative uncharacterized protein 426 e-117 B0PGT7.1 B0PGT7_9FIRM Putative uncharacterized protein 416 e-114 >B8I4M7.1 B8I4M7_CLOCE Alcohol dehydrogenase GroES domain protein Length = 346 Score = 507 bits (1305), Expect = e-142, Method: Compositional matrix adjust. Identities = 241/345 (69%), Positives = 289/345 (83%) Query: 1 MKNRAFYMTDLKKLEMNEIGMPKAKEGEVIVKLEYVGICGSDVHYLEHGRIGDFVVEGDF 60 MKNRA YMT++ K+E+ +I +PK +E +V+VKLEYVGICGSDVHYLEHG+IGDF+V GDF Sbjct: 1 MKNRAAYMTEINKMEIRDIEVPKLREKDVLVKLEYVGICGSDVHYLEHGKIGDFIVNGDF 60 Query: 61 ILGHECAGAVVELGPGVKNLKVGDRVALEPGVTCGQCEFCKSGKYNLCPDVKFLATPPYH 120 ILGHECAG VVE+G GV++LKVGD+VALEPG+TCGQCEFCK+G+YNLCPDV+FLATPPYH Sbjct: 61 ILGHECAGTVVEVGSGVQDLKVGDKVALEPGITCGQCEFCKTGRYNLCPDVEFLATPPYH 120 Query: 121 GCLMDYIAFPENMAFKLPDNVSSEEGALVEPLAVGLHAAAQGGIKLGDRVVILGAGCIGL 180 G LM+YIAFPENM FKLPDN++++EGALVEPLAVG+HAA QG +KLG VVILGAG IGL Sbjct: 121 GSLMNYIAFPENMCFKLPDNITTKEGALVEPLAVGMHAANQGEVKLGSSVVILGAGTIGL 180 Query: 181 VTLLACKAYGATDIVVVDIIEKRLEAAKRLGATRVINAKQENVRDVISLLTDGQGMDKVI 240 VTLLACKA GATDI VVD+I KRLE AK LGAT+ INA + +V I LTD +G+D VI Sbjct: 181 VTLLACKANGATDITVVDVIPKRLEYAKNLGATKTINAAEADVFAEIDKLTDKKGVDVVI 240 Query: 241 ETAGSEHTVKQTPYLVKRGGTIVLVGLAAKDIIDFDFMQIMFKEADIKSVFRYRNLYPXX 300 ETAG+ T+ QTPY+VK GG IVLVGLA +DII+F+F +IM KEA IKSVFRY+N+YP Sbjct: 241 ETAGTARTISQTPYMVKNGGNIVLVGLAPQDIIEFNFAKIMAKEATIKSVFRYKNIYPIA 300 Query: 301 XXXXXXXXXXVKGIVTHEFSFEDTQKAFDYVIDNKQEVVKAVIRM 345 + GIVTHEF+F+D AFDYVI+NKQ+VVKAVI++ Sbjct: 301 IKAISKGIIDITGIVTHEFNFDDVANAFDYVINNKQDVVKAVIKI 345 >C0C0V8.1 C0C0V8_9CLOT Putative uncharacterized protein Length = 346 Score = 491 bits (1265), Expect = e-137, Method: Compositional matrix adjust. Identities = 237/345 (68%), Positives = 284/345 (82%) Query: 1 MKNRAFYMTDLKKLEMNEIGMPKAKEGEVIVKLEYVGICGSDVHYLEHGRIGDFVVEGDF 60 MKNRA YMTDL K+E+ +I MPKA EV+V+LEYVGICGSDVHY GR GD+ VEGDF Sbjct: 1 MKNRAAYMTDLDKMEIRDIEMPKAGAKEVLVELEYVGICGSDVHYFHDGRCGDYKVEGDF 60 Query: 61 ILGHECAGAVVELGPGVKNLKVGDRVALEPGVTCGQCEFCKSGKYNLCPDVKFLATPPYH 120 +LGHECAG VVELG GV+NLKVGD+VALEPG+TCGQCEFCK+G+YNLCPDV+FLATPP Sbjct: 61 MLGHECAGTVVELGEGVENLKVGDKVALEPGITCGQCEFCKTGRYNLCPDVQFLATPPVQ 120 Query: 121 GCLMDYIAFPENMAFKLPDNVSSEEGALVEPLAVGLHAAAQGGIKLGDRVVILGAGCIGL 180 GC +YIAFPENM FKLP+N+S++EGALVEPL+VG+HAA QG +KLGD VVILGAGCIGL Sbjct: 121 GCYENYIAFPENMCFKLPENISTKEGALVEPLSVGMHAANQGDVKLGDSVVILGAGCIGL 180 Query: 181 VTLLACKAYGATDIVVVDIIEKRLEAAKRLGATRVINAKQENVRDVISLLTDGQGMDKVI 240 VTLLACKA+GATDI VVD+I KRL+ A +LGATRVIN K+ N + + LT G G+DKV Sbjct: 181 VTLLACKAHGATDITVVDVIPKRLDYAMKLGATRVINGKEVNAVEEMDKLTGGAGVDKVF 240 Query: 241 ETAGSEHTVKQTPYLVKRGGTIVLVGLAAKDIIDFDFMQIMFKEADIKSVFRYRNLYPXX 300 ETAGS T++QTPY+VK GGTIVLVG++A++ I+++F +IM KEA I+SVFRYRN+YP Sbjct: 241 ETAGSPVTIQQTPYMVKNGGTIVLVGISAQEKIEYNFAKIMAKEAKIESVFRYRNIYPQA 300 Query: 301 XXXXXXXXXXVKGIVTHEFSFEDTQKAFDYVIDNKQEVVKAVIRM 345 V GIVTHEF F+D Q+AFD I+NK EVVKAVI++ Sbjct: 301 IAAIADGMIDVSGIVTHEFDFDDIQEAFDCAINNKDEVVKAVIKI 345 >A6TKU9.1 A6TKU9_ALKMQ Alcohol dehydrogenase, zinc-binding domain protein Length = 346 Score = 440 bits (1131), Expect = e-121, Method: Compositional matrix adjust. Identities = 212/345 (61%), Positives = 267/345 (77%) Query: 1 MKNRAFYMTDLKKLEMNEIGMPKAKEGEVIVKLEYVGICGSDVHYLEHGRIGDFVVEGDF 60 MKNRA +M + ++ MPK KE +V++K++ VGICGSDVHY +HG+IGDFVVEG+F Sbjct: 1 MKNRAVFMQGTDNMVTKDVPMPKIKEKDVLIKVDIVGICGSDVHYYKHGKIGDFVVEGEF 60 Query: 61 ILGHECAGAVVELGPGVKNLKVGDRVALEPGVTCGQCEFCKSGKYNLCPDVKFLATPPYH 120 ILGHE AG VVE+G VK L VGDRV +EPG TCG+CEFCK GKYNLCPDV+F ATPPYH Sbjct: 61 ILGHEAAGEVVEVGEQVKGLTVGDRVTMEPGKTCGKCEFCKGGKYNLCPDVEFFATPPYH 120 Query: 121 GCLMDYIAFPENMAFKLPDNVSSEEGALVEPLAVGLHAAAQGGIKLGDRVVILGAGCIGL 180 G L +Y++ PE+M FKLP NVS+ EGALVEPLAVGLHA+ QGG+KLGD VVI G GCIGL Sbjct: 121 GVLTNYVSHPEDMCFKLPKNVSNVEGALVEPLAVGLHASDQGGVKLGDTVVIFGTGCIGL 180 Query: 181 VTLLACKAYGATDIVVVDIIEKRLEAAKRLGATRVINAKQENVRDVISLLTDGQGMDKVI 240 +T+++CKA GA I+VVDI+E RLE AK++GAT INAK+ NV I LTDG+G + VI Sbjct: 181 MTIISCKAKGAAKIIVVDILENRLEVAKKVGATDTINAKEVNVLKKIQELTDGKGAEVVI 240 Query: 241 ETAGSEHTVKQTPYLVKRGGTIVLVGLAAKDIIDFDFMQIMFKEADIKSVFRYRNLYPXX 300 + AG+ TVKQT VK GGTIVLVG+ KD ++F+FM++M KEA++K+VFRYRNLYP Sbjct: 241 DAAGAAITVKQTVDAVKPGGTIVLVGMTPKDEVEFNFMKLMGKEAEVKTVFRYRNLYPIA 300 Query: 301 XXXXXXXXXXVKGIVTHEFSFEDTQKAFDYVIDNKQEVVKAVIRM 345 +K IV+HEF FE T++AFD+V ++ +VVKAVI++ Sbjct: 301 INAIASGAINIKDIVSHEFDFEQTKEAFDFVAEHASDVVKAVIKI 345 >C0CQL1.1 C0CQL1_9FIRM Putative uncharacterized protein Length = 364 Score = 426 bits (1094), Expect = e-117, Method: Compositional matrix adjust. Identities = 208/345 (60%), Positives = 263/345 (76%), Gaps = 2/345 (0%) Query: 3 NRAFYMTDLKKLEMNEIGMPKAKEGEVIVKLEYVGICGSDVHYLEHGRIGDFVVE--GDF 60 + YM + K+ + EI +PKA+ +V+VK+EYVGICGSDVHY HG G + V+ DF Sbjct: 19 QKGAYMQGIDKMILKEIPVPKAEGKQVLVKIEYVGICGSDVHYFHHGCCGAYKVDLSEDF 78 Query: 61 ILGHECAGAVVELGPGVKNLKVGDRVALEPGVTCGQCEFCKSGKYNLCPDVKFLATPPYH 120 +LGHECAG VVE+G V +LKVGDRVALEPG+TCG+CEFCKSG YNLCPDV FLATPP Sbjct: 79 MLGHECAGTVVEVGKEVTDLKVGDRVALEPGITCGKCEFCKSGHYNLCPDVVFLATPPVQ 138 Query: 121 GCLMDYIAFPENMAFKLPDNVSSEEGALVEPLAVGLHAAAQGGIKLGDRVVILGAGCIGL 180 GC YIAFPE+M FKLP+N+S+ EG L+EPL+VG +AA QG ++ GD VVILGAGCIGL Sbjct: 139 GCYEQYIAFPEDMCFKLPENMSTLEGCLIEPLSVGFYAANQGEVQTGDTVVILGAGCIGL 198 Query: 181 VTLLACKAYGATDIVVVDIIEKRLEAAKRLGATRVINAKQENVRDVISLLTDGQGMDKVI 240 VTLLACKA+GA ++VVD+++ RLE AK LGAT VIN+K+++V + LT G+G D V Sbjct: 199 VTLLACKAHGAGQMIVVDLVDARLEKAKELGATAVINSKEKDVFQEVERLTGGRGGDVVF 258 Query: 241 ETAGSEHTVKQTPYLVKRGGTIVLVGLAAKDIIDFDFMQIMFKEADIKSVFRYRNLYPXX 300 ETAGS T+ QTP+LV+RGGTI LVG++A++ I+++F QIM KEA IKSVFRYRN+YP Sbjct: 259 ETAGSAVTIAQTPFLVRRGGTITLVGISAQEEINYNFAQIMDKEASIKSVFRYRNIYPKA 318 Query: 301 XXXXXXXXXXVKGIVTHEFSFEDTQKAFDYVIDNKQEVVKAVIRM 345 VK IVTHEF E Q+AFD ++NK ++VKAVI++ Sbjct: 319 ISAVASGAIDVKSIVTHEFDLEHIQEAFDEAVNNKTDLVKAVIKV 363 >B0PGT7.1 B0PGT7_9FIRM Putative uncharacterized protein Length = 349 Score = 416 bits (1069), Expect = e-114, Method: Compositional matrix adjust. Identities = 202/345 (58%), Positives = 256/345 (74%), Gaps = 2/345 (0%) Query: 3 NRAFYMTDLKKLEMNEIGMPKAKEGEVIVKLEYVGICGSDVHYLEHGRIGDFVVE--GDF 60 + +M + ++ + +I MPKA + EV+VKLEYVGICGSDVHY HG G + V+ D+ Sbjct: 4 QKGAFMRGIDQMIIKDIPMPKAGKKEVLVKLEYVGICGSDVHYFHHGNCGAYKVDLSNDY 63 Query: 61 ILGHECAGAVVELGPGVKNLKVGDRVALEPGVTCGQCEFCKSGKYNLCPDVKFLATPPYH 120 +LGHECAG VV +G V NLK GDRVALEPG+TCG CEFCKSG+YNLCPDV FLATPP Sbjct: 64 MLGHECAGTVVAVGEDVTNLKAGDRVALEPGITCGTCEFCKSGRYNLCPDVVFLATPPVQ 123 Query: 121 GCLMDYIAFPENMAFKLPDNVSSEEGALVEPLAVGLHAAAQGGIKLGDRVVILGAGCIGL 180 GC YIAFPENM FKLP+N+S+ EG L+EPL+VG +AA QG + GD VILGAGCIGL Sbjct: 124 GCYEQYIAFPENMCFKLPENMSTLEGCLIEPLSVGFYAANQGEVGTGDVAVILGAGCIGL 183 Query: 181 VTLLACKAYGATDIVVVDIIEKRLEAAKRLGATRVINAKQENVRDVISLLTDGQGMDKVI 240 VTLLACKA+GA I+V D+++ RLE A+ LGA VIN+ + ++ + + LT+G+G D V Sbjct: 184 VTLLACKAHGAGQIIVADLVDARLEKARELGAAAVINSGKTDLLEEVRRLTNGRGADVVF 243 Query: 241 ETAGSEHTVKQTPYLVKRGGTIVLVGLAAKDIIDFDFMQIMFKEADIKSVFRYRNLYPXX 300 ETAGS T+ QTP+LV+RGGTI LVG+AA++ I+++F QIM KEA IKSVFRYRN+YP Sbjct: 244 ETAGSAATIAQTPFLVRRGGTITLVGIAAQEEINYNFAQIMDKEATIKSVFRYRNIYPKA 303 Query: 301 XXXXXXXXXXVKGIVTHEFSFEDTQKAFDYVIDNKQEVVKAVIRM 345 +K IVTHEF E Q+AF I+NK ++VKAVI++ Sbjct: 304 IAAVASGAIDIKRIVTHEFDLEHIQEAFGEAINNKTDLVKAVIKV 348 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.322 0.141 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,960,680,801 Number of extensions: 82038470 Number of successful extensions: 272564 Number of sequences better than 1.0e-05: 10616 Number of HSP's gapped: 252770 Number of HSP's successfully gapped: 10841 Length of query: 346 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 210 Effective length of database: 1,779,438,163 Effective search space: 373682014230 Effective search space used: 373682014230 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 131 (55.1 bits)