BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0437.0002.p (365 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value O34989.2 YVRG_BACSU Sensor histidine kinase yvrG EC=2.7.13.3 196 4e-48 A7Z8N9.1 A7Z8N9_BACA2 Sensor protein EC=2.7.13.3 188 6e-46 C2W6K9.1 C2W6K9_BACCE Putative uncharacterized protein 184 2e-44 Q65F20.1 Q65F20_BACLD Sensor protein EC=2.7.13.3 183 3e-44 B3KHB4.1 B3KHB4_9BACI Sensor protein EC=2.7.13.3 182 4e-44 >O34989.2 YVRG_BACSU Sensor histidine kinase yvrG EC=2.7.13.3 Length = 580 Score = 196 bits (497), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 110/328 (33%), Positives = 174/328 (53%), Gaps = 22/328 (6%) Query: 55 SFLAVCLAAL---------------AFYLWSLMKPVFYMLTWLKRLAQGHYDEPSRSNWR 99 SFL V L A+ +Y++ P+F+ + WL L++G +EP N Sbjct: 253 SFLKVVLKAMFLVMAVLFMYIIWMTVWYMFRFGLPIFHTIRWLVNLSKGKLEEPR--NRE 310 Query: 100 GRPLSGNQ---LKLPYTLFREIIGQMSMLTLALQXXXXXXXXXXXXXXSWIAGVRHDLKT 156 GRP+S N+ +K PY F EI M LT L+ WIAG+ HDLKT Sbjct: 311 GRPVSKNKKGKIKQPYRFFGEIFESMDQLTETLRRDKRNREKIQATREEWIAGLSHDLKT 370 Query: 157 PLAYIRGYSSMIAAADQYQWSTAEIIQFGSLMEQKTIQVEQLIEDMNASYQLDGSEGPLS 216 PL+ I GYS M+ + QY WS E+ + G ++ +K+ + +LIED+N +Y+L P+ Sbjct: 371 PLSSIYGYSMMLESK-QYDWSPEEVKEMGQVVREKSEYMSKLIEDLNLTYRLKNDALPIE 429 Query: 217 RESTEMAGFIRQIVTDVADHPLAAQHTFAFNTAGEKC-LDIDQRMIRRALHNLLWNAVVH 275 R+ T + F + ++ D +P + + +F + E +D+ RR L NLL NAV H Sbjct: 430 RKLTSLIPFFKNVIEDFKKNPFSEGYDISFVSKEEHIEFALDEAWFRRILENLLGNAVKH 489 Query: 276 NPAGCHIEAEVYWDQHGLTVEIRDNGTGIDAETLERLNTAEDNVLSARARLAGSGLGMAL 335 N G I+ + ++ ++++++DNG G+D ET+ L + + AG+GLG+A+ Sbjct: 490 NGKGTEIQVILEQTKNHISLKVKDNGKGMDEETITHLFNRYYRGTNTKDSTAGTGLGLAI 549 Query: 336 AKGFVTRHDGTMTVHSKPQQGTRITLFF 363 AK V H+GT+ V+S+ GT IT+ F Sbjct: 550 AKELVHLHNGTIHVNSRTNIGTVITILF 577 >A7Z8N9.1 A7Z8N9_BACA2 Sensor protein EC=2.7.13.3 Length = 580 Score = 188 bits (478), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 106/309 (34%), Positives = 165/309 (53%), Gaps = 8/309 (2%) Query: 59 VCLAALAFYLWSLMKPVFYMLTWLKRLAQGHYDEPSRSNWRGRPLSGNQ---LKLPYTLF 115 +C+ + +Y + P+F+ + WL L++G +EP N +G+P+S N+ K P+ F Sbjct: 273 ICILTI-WYSFRFGWPLFHTIKWLVNLSKGRLEEPK--NRKGQPVSKNKKGKTKQPFRFF 329 Query: 116 REIIGQMSMLTLALQXXXXXXXXXXXXXXSWIAGVRHDLKTPLAYIRGYSSMIAAADQYQ 175 EI M LT L+ WIAG+ HDLKTPL+ I GYS M+ + QY Sbjct: 330 AEIFESMDQLTDTLKRDKKNREKIQATREEWIAGLSHDLKTPLSTIYGYSMMLESK-QYD 388 Query: 176 WSTAEIIQFGSLMEQKTIQVEQLIEDMNASYQLDGSEGPLSRESTEMAGFIRQIVTDVAD 235 W+ E+ + G ++ +K+ + +LIED+N +Y+L + P+ R + FIR + D Sbjct: 389 WTPEEVKEMGQIVREKSEYMSKLIEDLNLTYRLKNAALPIERRLINVVPFIRNVTNDFTK 448 Query: 236 HPLAAQHTFAFNTAGEKCL-DIDQRMIRRALHNLLWNAVVHNPAGCHIEAEVYWDQHGLT 294 + + + AF T E L ID+ RR L NLL NAV HN G I + L Sbjct: 449 NTFSEGYDIAFETKKEDILFAIDEAWFRRILENLLANAVKHNKKGTAIRVVLEESAEQLI 508 Query: 295 VEIRDNGTGIDAETLERLNTAEDNVLSARARLAGSGLGMALAKGFVTRHDGTMTVHSKPQ 354 ++++DNG G+D ET+ +L + + G+GLG+A+AK V H+GT+ V+S+ Sbjct: 509 LKVKDNGRGMDDETIHQLFNRYYRGTNTKGPSEGTGLGLAIAKELVHLHNGTIHVNSRIS 568 Query: 355 QGTRITLFF 363 GT IT+ F Sbjct: 569 AGTVITILF 577 >C2W6K9.1 C2W6K9_BACCE Putative uncharacterized protein Length = 342 Score = 184 bits (466), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 97/309 (31%), Positives = 166/309 (53%), Gaps = 4/309 (1%) Query: 56 FLAVCLAALAFYLWSLMKPVFYMLTWLKRLAQGHYDEPSRSNWRGRPLSGNQLKLPYTLF 115 F+ L Y W + +P+F M++W+ +LA+G Y P+ + + +G +LK PY L+ Sbjct: 34 FICTLLIGAIIYGWHISRPLFRMISWINQLAEGSYVTPANTKQMYKKKTG-KLKGPYRLY 92 Query: 116 REIIGQMSMLTLALQXXXXXXXXXXXXXXSWIAGVRHDLKTPLAYIRGYSSMIAAADQYQ 175 +++ + LT L+ W+ G+ HDLKTPL YI GYS+++ + D + Sbjct: 93 KDVFLNIEHLTNRLREIETEREQLEKMKREWMVGISHDLKTPLTYITGYSALMLSPD-HT 151 Query: 176 WSTAEIIQFGSLMEQKTIQVEQLIEDMNASYQLDGSEGPLSRESTEMAGFIRQIVTDVAD 235 WS E +F ++QK +++LIED+N S++L S+ PL +E + F R+++ D+ + Sbjct: 152 WSHEEKEKFLQEIQQKGDHMKELIEDLNLSFRLQDSQIPLKKEEINIVEFTRRLIADITN 211 Query: 236 HPLAAQHTFAFNTAGEK-CLDIDQRMIRRALHNLLWNAVVHNPAGCHIEAEVYWDQHGLT 294 P + Q+ F+F ++ + ID ++ R+L NL NAV+HNP I + Q + Sbjct: 212 DPRSQQYHFSFESSNTNIIIPIDTKLFHRSLQNLFMNAVLHNPPETSIHTSILL-QEDIH 270 Query: 295 VEIRDNGTGIDAETLERLNTAEDNVLSARARLAGSGLGMALAKGFVTRHDGTMTVHSKPQ 354 + I D G G+D T++ L + G+GLGMA+A +T H GT+ V S+ Sbjct: 271 IIIEDTGAGMDELTVQNLFKQYYRGTTTNVSNEGTGLGMAIAHKIITAHGGTIHVTSEIG 330 Query: 355 QGTRITLFF 363 G++I + Sbjct: 331 TGSKIHIIL 339 >Q65F20.1 Q65F20_BACLD Sensor protein EC=2.7.13.3 Length = 585 Score = 183 bits (464), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 101/294 (34%), Positives = 157/294 (53%), Gaps = 7/294 (2%) Query: 74 PVFYMLTWLKRLAQGHYDEPSRSNWRGRPLSGNQL---KLPYTLFREIIGQMSMLTLALQ 130 P+ + + W+ L++G ++EP N +GRP S N+ K PY LF E+ M LT L+ Sbjct: 287 PIIHTIKWIVNLSKGRFEEPR--NRKGRPRSRNKKGKRKQPYRLFTEVFESMEQLTETLK 344 Query: 131 XXXXXXXXXXXXXXSWIAGVRHDLKTPLAYIRGYSSMIAAADQYQWSTAEIIQFGSLMEQ 190 WIAG+ HDLKTPL+ I GYS M+ + + Y+WS EI + G M++ Sbjct: 345 KDEQNRKKIQTTREEWIAGLSHDLKTPLSTIYGYSMMLESPN-YEWSKEEIREIGQAMKE 403 Query: 191 KTIQVEQLIEDMNASYQLDGSEGPLSRESTEMAGFIRQIVTDVADHPLAAQHTFAFNTAG 250 K+ + QLIED+N +Y+L P+ R++ + F++ V + H + + +F Sbjct: 404 KSDYMSQLIEDLNLTYRLKNDALPIKRQTVRLVPFLKSFVEEFKRHSFSEGYNVSFEYKQ 463 Query: 251 -EKCLDIDQRMIRRALHNLLWNAVVHNPAGCHIEAEVYWDQHGLTVEIRDNGTGIDAETL 309 + ID+ RR L NLL NAV HN G I+ + + + ++I+DNG G+D+ET+ Sbjct: 464 VDTEFAIDRGWFRRVLENLLANAVKHNKKGTDIKVILEESKQYIILKIQDNGRGMDSETV 523 Query: 310 ERLNTAEDNVLSARARLAGSGLGMALAKGFVTRHDGTMTVHSKPQQGTRITLFF 363 L + GSGLG+A++ V HDG + V S+ +GT IT+ F Sbjct: 524 SNLFNRYYRGTHTKDATEGSGLGLAISLELVHLHDGCIAVDSRTGRGTEITMEF 577 >B3KHB4.1 B3KHB4_9BACI Sensor protein EC=2.7.13.3 Length = 369 Score = 182 bits (463), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 99/310 (31%), Positives = 170/310 (54%), Gaps = 8/310 (2%) Query: 56 FLAVCLAALAFYLWSLMKPVFYMLTWLKRLAQGHYDEPSR-SNWRGRPLSGNQLKLPYTL 114 F A L +A + W P+ +++TW+++L++ Y +P+ S R +L++ Y+L Sbjct: 54 FGASTLLCIALFGWYFGGPIGFIMTWIQQLSKDDYKQPAELSKIVTRK---GKLRMRYSL 110 Query: 115 FREIIGQMSMLTLALQXXXXXXXXXXXXXXSWIAGVRHDLKTPLAYIRGYSSMIAAADQY 174 ++E++ + L LQ WIAG+ HDLKTPL YI+GYS+++ +QY Sbjct: 111 YQEVLQHLQSLGSVLQANEAERTQIEQAKQEWIAGISHDLKTPLTYIKGYSALL-LNEQY 169 Query: 175 QWSTAEIIQFGSLMEQKTIQVEQLIEDMNASYQLDGSEG--PLSRESTEMAGFIRQIVTD 232 +WS E I F M+ K +E+LI+D++ QL+ ++G PL + + ++ F +++V D Sbjct: 170 EWSKEEAISFIREMDDKGKHMEELIQDLSLVTQLNRADGALPLLKANQDIVEFTKRVVAD 229 Query: 233 VADHPLAAQHTFAFNTAGEKC-LDIDQRMIRRALHNLLWNAVVHNPAGCHIEAEVYWDQH 291 ++++P A+ + F T +D D + ++R L N++ N+++HNP I + Sbjct: 230 ISNNPQASNYLLHFQTDSSAMHVDFDAKYMQRILQNIMINSIIHNPEFTEIFVRITDAGE 289 Query: 292 GLTVEIRDNGTGIDAETLERLNTAEDNVLSARARLAGSGLGMALAKGFVTRHDGTMTVHS 351 + I DNG G+ A+T+ L + A G+GLGMA+ + HDGT+TV S Sbjct: 290 FAAIRITDNGIGMPADTVAHLFQQYYRGTTTDAASEGTGLGMAIVYKLIQAHDGTITVES 349 Query: 352 KPQQGTRITL 361 KP QGT T+ Sbjct: 350 KPSQGTTFTI 359 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.324 0.136 0.423 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,908,774,884 Number of extensions: 72875745 Number of successful extensions: 313735 Number of sequences better than 1.0e-05: 9055 Number of HSP's gapped: 311708 Number of HSP's successfully gapped: 9056 Length of query: 365 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 228 Effective length of database: 1,770,017,148 Effective search space: 403563909744 Effective search space used: 403563909744 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 132 (55.5 bits)