BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0435.0008.p (161 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KEK8.1 B3KEK8_9BACI Alcohol dehydrogenase GroES domain protein 309 5e-83 B1DGU9.1 B1DGU9_9BACL Alcohol dehydrogenase GroES domain protein 292 7e-78 C1PXR0.1 C1PXR0_ALIAC Zn-dependent alcohol dehydrogenase EC=1.1.... 253 4e-66 B7DRU7.1 B7DRU7_9BACL Alcohol dehydrogenase GroES domain protein 252 6e-66 A1R6C3.1 A1R6C3_ARTAT NADP-dependent alcohol dehydrogenase EC=1.... 251 1e-65 >B3KEK8.1 B3KEK8_9BACI Alcohol dehydrogenase GroES domain protein Length = 348 Score = 309 bits (792), Expect = 5e-83, Method: Compositional matrix adjust. Identities = 149/161 (92%), Positives = 157/161 (97%) Query: 1 MAVKLAHAMGAEVTVLSQTLKKKEDGLKLGADHYYATSDPETFKKLTGKFDLIVNTVSAK 60 MAVKLAHAMGA+VTVLSQTLKKKEDGLKLGADHYYAT+DPETF KL G FDLIVNTVSAK Sbjct: 188 MAVKLAHAMGADVTVLSQTLKKKEDGLKLGADHYYATNDPETFNKLAGTFDLIVNTVSAK 247 Query: 61 IDLDAYLSLLAVNGTLVNVGAPPEALPIQVFSLIGHRRSFAGSAIGGIRETQEMLDFCAK 120 IDL+AYLSLLAV+GTLVNVGAPPEALP+QVFSLI HRRSFAGSAIGGIRETQEMLDFCA+ Sbjct: 248 IDLNAYLSLLAVDGTLVNVGAPPEALPVQVFSLIPHRRSFAGSAIGGIRETQEMLDFCAE 307 Query: 121 HHITPEIEVISANQIDQAWERVLASDVRYRFVIDISTMENE 161 HHITPEIEVISAN+ID+AWERVLASDVRYRFVIDISTMENE Sbjct: 308 HHITPEIEVISANRIDEAWERVLASDVRYRFVIDISTMENE 348 >B1DGU9.1 B1DGU9_9BACL Alcohol dehydrogenase GroES domain protein Length = 349 Score = 292 bits (748), Expect = 7e-78, Method: Compositional matrix adjust. Identities = 139/161 (86%), Positives = 152/161 (94%) Query: 1 MAVKLAHAMGAEVTVLSQTLKKKEDGLKLGADHYYATSDPETFKKLTGKFDLIVNTVSAK 60 MAVKLAHAMGAEVTVLSQ+LKKKEDGL+LGADHYYATSDPETFK+L FDLIVNTVSAK Sbjct: 189 MAVKLAHAMGAEVTVLSQSLKKKEDGLQLGADHYYATSDPETFKQLASSFDLIVNTVSAK 248 Query: 61 IDLDAYLSLLAVNGTLVNVGAPPEALPIQVFSLIGHRRSFAGSAIGGIRETQEMLDFCAK 120 ID++AYLSLLAV+GTLVNVGAP E LP+QVFSLI RRSFAGS+IGGIRETQEMLDFCA+ Sbjct: 249 IDINAYLSLLAVDGTLVNVGAPSEPLPVQVFSLIPQRRSFAGSSIGGIRETQEMLDFCAE 308 Query: 121 HHITPEIEVISANQIDQAWERVLASDVRYRFVIDISTMENE 161 H ITPEIEVISAN+ID+AWERVLASDVRYRFVID+STM N+ Sbjct: 309 HQITPEIEVISANRIDEAWERVLASDVRYRFVIDVSTMRNQ 349 >C1PXR0.1 C1PXR0_ALIAC Zn-dependent alcohol dehydrogenase EC=1.1.1.255 Length = 376 Score = 253 bits (646), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 120/160 (75%), Positives = 137/160 (85%) Query: 1 MAVKLAHAMGAEVTVLSQTLKKKEDGLKLGADHYYATSDPETFKKLTGKFDLIVNTVSAK 60 MAVKLA AMGA+VTVLSQ+L+KKEDGL+LGA YYATSDPETF++L G+FDLI+NTVSAK Sbjct: 217 MAVKLAKAMGAKVTVLSQSLRKKEDGLRLGAKAYYATSDPETFRQLAGRFDLIINTVSAK 276 Query: 61 IDLDAYLSLLAVNGTLVNVGAPPEALPIQVFSLIGHRRSFAGSAIGGIRETQEMLDFCAK 120 I + YL LL +G LVNVGAPPE L + F+LI RR+FAGS IGGIRETQEMLDFCA+ Sbjct: 277 IPITEYLGLLKTDGALVNVGAPPEPLEVNAFALIAQRRTFAGSCIGGIRETQEMLDFCAE 336 Query: 121 HHITPEIEVISANQIDQAWERVLASDVRYRFVIDISTMEN 160 +TPEIEVISA++ID AWERVL SDVRYRFVIDISTM N Sbjct: 337 SGVTPEIEVISADEIDAAWERVLKSDVRYRFVIDISTMRN 376 >B7DRU7.1 B7DRU7_9BACL Alcohol dehydrogenase GroES domain protein Length = 347 Score = 252 bits (644), Expect = 6e-66, Method: Compositional matrix adjust. Identities = 120/160 (75%), Positives = 136/160 (85%) Query: 1 MAVKLAHAMGAEVTVLSQTLKKKEDGLKLGADHYYATSDPETFKKLTGKFDLIVNTVSAK 60 MAVKLA AMGAEVTVLSQ+L+KKEDGL+LGA YYATSDP+TF+ L G+FDLI+NTVSAK Sbjct: 188 MAVKLAKAMGAEVTVLSQSLRKKEDGLRLGAKAYYATSDPQTFRDLAGRFDLIINTVSAK 247 Query: 61 IDLDAYLSLLAVNGTLVNVGAPPEALPIQVFSLIGHRRSFAGSAIGGIRETQEMLDFCAK 120 I + YL LL +G LVNVGAPPE L + F+LI RR+FAGS IGGIRETQEMLDFCA+ Sbjct: 248 IPITEYLGLLKTDGALVNVGAPPEPLEVNAFALIAQRRTFAGSCIGGIRETQEMLDFCAE 307 Query: 121 HHITPEIEVISANQIDQAWERVLASDVRYRFVIDISTMEN 160 +TPEIEVISA++ID AWERVL SDVRYRFVIDISTM N Sbjct: 308 RGVTPEIEVISADEIDAAWERVLKSDVRYRFVIDISTMRN 347 >A1R6C3.1 A1R6C3_ARTAT NADP-dependent alcohol dehydrogenase EC=1.1.1.2 Length = 347 Score = 251 bits (642), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 122/158 (77%), Positives = 139/158 (87%) Query: 1 MAVKLAHAMGAEVTVLSQTLKKKEDGLKLGADHYYATSDPETFKKLTGKFDLIVNTVSAK 60 MAVK+AHAMGAEVTVLSQ+LKK EDGLKLGADHYYATSDP TF++L G FDLIVNTVSA Sbjct: 189 MAVKIAHAMGAEVTVLSQSLKKMEDGLKLGADHYYATSDPATFEQLGGTFDLIVNTVSAS 248 Query: 61 IDLDAYLSLLAVNGTLVNVGAPPEALPIQVFSLIGHRRSFAGSAIGGIRETQEMLDFCAK 120 ID+ AYL LL ++GTLVNVGAP E LP+ VFSLI RR FAGSAIGGIRETQEML+FCA+ Sbjct: 249 IDISAYLQLLTLDGTLVNVGAPAEPLPVNVFSLITGRRRFAGSAIGGIRETQEMLNFCAE 308 Query: 121 HHITPEIEVISANQIDQAWERVLASDVRYRFVIDISTM 158 H + EIEVI A++I+ A+ERVLASDVRYRFVID+ST+ Sbjct: 309 HGLGAEIEVIPASKINDAYERVLASDVRYRFVIDVSTI 346 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.134 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 899,379,753 Number of extensions: 33624393 Number of successful extensions: 96717 Number of sequences better than 1.0e-05: 1337 Number of HSP's gapped: 95834 Number of HSP's successfully gapped: 1339 Length of query: 161 Length of database: 3,060,696,203 Length adjustment: 121 Effective length of query: 40 Effective length of database: 1,920,753,388 Effective search space: 76830135520 Effective search space used: 76830135520 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 126 (53.1 bits)