BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0435.0003.p (335 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KDC5.1 B3KDC5_9BACI Aldo/keto reductase 492 e-137 C4C5T8.1 C4C5T8_9FUSO Predicted oxidoreductase similar to aryl-a... 492 e-137 C4LEW3.1 C4LEW3_TOLAT Aldo/keto reductase 469 e-130 C0V1B6.1 C0V1B6_9BACT Predicted oxidoreductase similar to aryl-a... 468 e-130 B1DLH5.1 B1DLH5_9BACL Aldo/keto reductase 465 e-129 >B3KDC5.1 B3KDC5_9BACI Aldo/keto reductase Length = 326 Score = 492 bits (1266), Expect = e-137, Method: Compositional matrix adjust. Identities = 238/327 (72%), Positives = 272/327 (83%), Gaps = 5/327 (1%) Query: 9 MDYTKLGNTGLDVSRICLGCMGFGDPDKGHHRWVLDEKSARPIIQKALDIGINFFDTANV 68 M+Y KLGNTGLDVSRICLGCMGFG ++ H+WVL+E+S+RPII+KAL++GINFFDTANV Sbjct: 1 MEYVKLGNTGLDVSRICLGCMGFGVAERWVHQWVLNEESSRPIIKKALELGINFFDTANV 60 Query: 69 YAEGTSEEIVGNVLKELADRDEIVIATKIHGRMHQGPNGAGLSRKAIMSEIDKSLKRLKT 128 Y++GTSEEIVG LKE A+RDEIV+ATK+H RMH+GPNG GLSRKAIMSEIDKSLKRL T Sbjct: 61 YSDGTSEEIVGRALKEYANRDEIVLATKVHFRMHEGPNGMGLSRKAIMSEIDKSLKRLGT 120 Query: 129 DYVDLYQIHRWDYNTPIEETIEALHDVVKAGKARYIGXXXXSAMWAWQFQKALHAAEKNG 188 DYVDLYQIHRWDY+TPIEET+EALHDVVKAGK RYIG SAM+AWQF KA H AEKNG Sbjct: 121 DYVDLYQIHRWDYDTPIEETMEALHDVVKAGKVRYIG---ASAMYAWQFLKAQHTAEKNG 177 Query: 189 WTRFVSMQNHLNLIYREEEREMLPLCKEEKIGVIPYSPLAGGRLAREAS--TPRAETDEI 246 WTRFVSMQNH NLIYREEEREMLPLC+ EKIGVIPYSPLA GRL R+ S T R+ETD + Sbjct: 178 WTRFVSMQNHYNLIYREEEREMLPLCQSEKIGVIPYSPLASGRLTRDWSETTQRSETDMV 237 Query: 247 AKQKYXXXXXXXXXXXXXXXNLAEKHGVRRVHIALAWLLHKEPVTAPIVGATKITQLEDA 306 K KY +A + G+ RV +ALAWLL KEP+TAPIVGATKI+ LEDA Sbjct: 238 QKSKYDATADADRIIVERLAGIANERGIPRVQVALAWLLQKEPITAPIVGATKISHLEDA 297 Query: 307 EAALSLKLTQEEISFLEEPYVPHRVVG 333 AAL++KLT EE++ LEEPY+PHRVVG Sbjct: 298 AAALTVKLTPEEMASLEEPYIPHRVVG 324 >C4C5T8.1 C4C5T8_9FUSO Predicted oxidoreductase similar to aryl-alcohol dehydrogenase Length = 326 Score = 492 bits (1266), Expect = e-137, Method: Compositional matrix adjust. Identities = 233/327 (71%), Positives = 271/327 (82%), Gaps = 5/327 (1%) Query: 9 MDYTKLGNTGLDVSRICLGCMGFGDPDKGHHRWVLDEKSARPIIQKALDIGINFFDTANV 68 M+Y KLGNTG+DVSR CLGCMGFGD + H+W+L+E+ +RP+I+KALD+GINFFDTANV Sbjct: 1 MEYIKLGNTGMDVSRFCLGCMGFGDSEAWVHKWLLNEEDSRPVIKKALDLGINFFDTANV 60 Query: 69 YAEGTSEEIVGNVLKELADRDEIVIATKIHGRMHQGPNGAGLSRKAIMSEIDKSLKRLKT 128 Y+ G SEEI+G LK+ A+RDE+VIATK+HG+MH GPNG+GLSRKAIMSEIDKSLKRL T Sbjct: 61 YSLGKSEEILGRALKDYANRDEVVIATKVHGKMHDGPNGSGLSRKAIMSEIDKSLKRLGT 120 Query: 129 DYVDLYQIHRWDYNTPIEETIEALHDVVKAGKARYIGXXXXSAMWAWQFQKALHAAEKNG 188 DYVDLY IHRWDYNTPIEET+EALHD+VKAGKARYIG SAM+AWQFQKALH AEKNG Sbjct: 121 DYVDLYIIHRWDYNTPIEETMEALHDIVKAGKARYIG---ASAMYAWQFQKALHTAEKNG 177 Query: 189 WTRFVSMQNHLNLIYREEEREMLPLCKEEKIGVIPYSPLAGGRLAREAS--TPRAETDEI 246 WTRFVSMQNHLNLIYREEEREM+PLCKEEKI + PYSPLA GRL R S T R+ETD+I Sbjct: 178 WTRFVSMQNHLNLIYREEEREMIPLCKEEKIALTPYSPLASGRLTRNLSETTKRSETDQI 237 Query: 247 AKQKYXXXXXXXXXXXXXXXNLAEKHGVRRVHIALAWLLHKEPVTAPIVGATKITQLEDA 306 A KY +AE+ G+ R+H+ALAWLL KEPVT PI+GATK++ LEDA Sbjct: 238 AVSKYGSTEEADRLVIERLAAVAERRGIPRLHVALAWLLQKEPVTIPIIGATKLSHLEDA 297 Query: 307 EAALSLKLTQEEISFLEEPYVPHRVVG 333 ALS+KL EEI+FLEEPYVPH+V+G Sbjct: 298 VPALSVKLEPEEIAFLEEPYVPHKVIG 324 >C4LEW3.1 C4LEW3_TOLAT Aldo/keto reductase Length = 327 Score = 469 bits (1208), Expect = e-130, Method: Compositional matrix adjust. Identities = 223/329 (67%), Positives = 264/329 (80%), Gaps = 6/329 (1%) Query: 9 MDYTKLGNTGLDVSRICLGCMGFGDPDKGHHRWVLDEKSARPIIQKALDIGINFFDTANV 68 M+Y KLGNTGLDVSRICLGCMGFGDP+K H WVL E+ +R II+KAL++GINFFDTANV Sbjct: 1 MEYVKLGNTGLDVSRICLGCMGFGDPNKWVHSWVLQEEDSRIIIKKALELGINFFDTANV 60 Query: 69 YAEGTSEEIVGNVLKELADRDEIVIATKIHGRMHQGPNGAGLSRKAIMSEIDKSLKRLKT 128 Y+ G SEEI+G +++ A+RDE+V+ATKIHG+MHQGPNG GLSRKAIMSE+DKSLKRL+ Sbjct: 61 YSLGASEEILGRAIRDYANRDEVVVATKIHGQMHQGPNGKGLSRKAIMSELDKSLKRLEM 120 Query: 129 DYVDLYQIHRWDYNTPIEETIEALHDVVKAGKARYIGXXXXSAMWAWQFQKALHAAEKNG 188 DYVDLY IHRWDYNTPIEET+ ALHDVVK+GK RYIG SAM+AWQF KA + AEKNG Sbjct: 121 DYVDLYIIHRWDYNTPIEETMAALHDVVKSGKVRYIG---ASAMYAWQFHKAQNIAEKNG 177 Query: 189 WTRFVSMQNHLNLIYREEEREMLPLCKEEKIGVIPYSPLAGGRLARE---ASTPRAETDE 245 WTRFVSMQNHLNLIYREEEREM+PLC++++I + PYSPLA GRL R+ +T R+E+D+ Sbjct: 178 WTRFVSMQNHLNLIYREEEREMIPLCRDQQIAITPYSPLASGRLTRDWTAEATKRSESDK 237 Query: 246 IAKQKYXXXXXXXXXXXXXXXNLAEKHGVRRVHIALAWLLHKEPVTAPIVGATKITQLED 305 IA KY +AEK V R HIALAWLL K+PV API+GATKI+ LE Sbjct: 238 IAMSKYDATVDADRTVIERLAEIAEKRDVPRTHIALAWLLQKQPVVAPIIGATKISHLET 297 Query: 306 AEAALSLKLTQEEISFLEEPYVPHRVVGH 334 A +LSLKLT EEI ++E PYVPH +VGH Sbjct: 298 AIGSLSLKLTAEEIDYMEAPYVPHNIVGH 326 >C0V1B6.1 C0V1B6_9BACT Predicted oxidoreductase similar to aryl-alcohol dehydrogenase Length = 332 Score = 468 bits (1204), Expect = e-130, Method: Compositional matrix adjust. Identities = 223/328 (67%), Positives = 269/328 (82%), Gaps = 6/328 (1%) Query: 9 MDYTKLGNTGLDVSRICLGCMGFGDPDKGHHRWVLDEKSARPIIQKALDIGINFFDTANV 68 M+YT+LGNTGL+VSRICLGCMGFGDPD+ H+WVL E+ +R +I++ALD+GINFFDTANV Sbjct: 1 MEYTRLGNTGLEVSRICLGCMGFGDPDRWVHKWVLREEESRQVIKQALDLGINFFDTANV 60 Query: 69 YAEGTSEEIVGNVLKELADRDEIVIATKIHGRMHQGPNGAGLSRKAIMSEIDKSLKRLKT 128 Y+ G SEEI+G L++ A R+E+VIATK++GRM GPNGAGLSRKAIM+EID SL+RL T Sbjct: 61 YSLGVSEEILGRALRDFASRNEVVIATKVYGRMRPGPNGAGLSRKAIMTEIDHSLRRLGT 120 Query: 129 DYVDLYQIHRWDYNTPIEETIEALHDVVKAGKARYIGXXXXSAMWAWQFQKALHAAEKNG 188 DYVDLYQIHRWDY+TPIEET+EALHD+VKAGK RYIG SAM+AWQFQKAL+ AE++G Sbjct: 121 DYVDLYQIHRWDYDTPIEETMEALHDLVKAGKVRYIG---ASAMFAWQFQKALYVAERHG 177 Query: 189 WTRFVSMQNHLNLIYREEEREMLPLCKEEKIGVIPYSPLAGGRLAR---EASTPRAETDE 245 WTRFVSMQNH+NLIYREEEREMLPLC+EE IGVIPYSPLA GRL R + S+ RA+TDE Sbjct: 178 WTRFVSMQNHMNLIYREEEREMLPLCREEGIGVIPYSPLAAGRLTRDWSQESSLRAQTDE 237 Query: 246 IAKQKYXXXXXXXXXXXXXXXNLAEKHGVRRVHIALAWLLHKEPVTAPIVGATKITQLED 305 IAK KY +A +HGV R +ALAWLL K+PV API+GATK LE+ Sbjct: 238 IAKGKYDAMADADWQIIERVAEVARRHGVTRAQVALAWLLGKQPVVAPIIGATKPEHLEE 297 Query: 306 AEAALSLKLTQEEISFLEEPYVPHRVVG 333 A ALS++L+ E++++LEEPYVPH VVG Sbjct: 298 AVGALSVQLSPEDVAYLEEPYVPHPVVG 325 >B1DLH5.1 B1DLH5_9BACL Aldo/keto reductase Length = 326 Score = 465 bits (1197), Expect = e-129, Method: Compositional matrix adjust. Identities = 222/327 (67%), Positives = 262/327 (80%), Gaps = 5/327 (1%) Query: 9 MDYTKLGNTGLDVSRICLGCMGFGDPDKGHHRWVLDEKSARPIIQKALDIGINFFDTANV 68 M+Y KLGNTGLDVSR+CLGCM FG+ ++ +H W+LDE+++RPII+KALD+GINFFDTAN+ Sbjct: 1 MEYVKLGNTGLDVSRLCLGCMSFGEVERWNHPWILDEENSRPIIKKALDLGINFFDTANI 60 Query: 69 YAEGTSEEIVGNVLKELADRDEIVIATKIHGRMHQGPNGAGLSRKAIMSEIDKSLKRLKT 128 Y+ G SEEIVG LK+ A+RDE+VIA+K+ RM GPNGAGLSRKAIM+EID SLKRL T Sbjct: 61 YSTGASEEIVGRALKDYANRDEVVIASKVFFRMQPGPNGAGLSRKAIMNEIDNSLKRLGT 120 Query: 129 DYVDLYQIHRWDYNTPIEETIEALHDVVKAGKARYIGXXXXSAMWAWQFQKALHAAEKNG 188 DYVDLYQIHRWDYNTPIEET+EALHDVVKAGKARYIG SAM+AWQFQKALH AE+NG Sbjct: 121 DYVDLYQIHRWDYNTPIEETMEALHDVVKAGKARYIG---ASAMYAWQFQKALHVAEQNG 177 Query: 189 WTRFVSMQNHLNLIYREEEREMLPLCKEEKIGVIPYSPLAGGRLAR--EASTPRAETDEI 246 WTRFV+MQNHLNL+YREEEREM+PL KEEKIG IPYSPLA GRL R + T R+ETD+ Sbjct: 178 WTRFVAMQNHLNLMYREEEREMMPLLKEEKIGAIPYSPLASGRLVRDWDTVTHRSETDQA 237 Query: 247 AKQKYXXXXXXXXXXXXXXXNLAEKHGVRRVHIALAWLLHKEPVTAPIVGATKITQLEDA 306 K KY +AE+ GV RV +ALAWLL KE VTAPI+G T + QLE+ Sbjct: 238 QKMKYDAFAEQDRVIAERVAEIAEQRGVPRVQVALAWLLQKEQVTAPIIGVTSMAQLEET 297 Query: 307 EAALSLKLTQEEISFLEEPYVPHRVVG 333 ++ L LT +E+ +LEE YVPHRVVG Sbjct: 298 IGSIELTLTPDEVKYLEEQYVPHRVVG 324 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,919,518,618 Number of extensions: 74229489 Number of successful extensions: 202942 Number of sequences better than 1.0e-05: 6710 Number of HSP's gapped: 187205 Number of HSP's successfully gapped: 6732 Length of query: 335 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 199 Effective length of database: 1,779,438,163 Effective search space: 354108194437 Effective search space used: 354108194437 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)