BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0422.0012.p (530 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KL04.1 B3KL04_9BACI ATP-dependent protease La 921 0.0 Q84FG5.1 Q84FG5_9BACL ATP-dependent protease La 781 0.0 P36772.1 LON_BRECH ATP-dependent protease La EC=3.4.21.53 778 0.0 C5D5L2.1 C5D5L2_9BACI ATP-dependent protease La EC=3.4.21.53 777 0.0 C0ZAG5.1 C0ZAG5_BREBN ATP-dependent protease La EC=3.4.21.53 777 0.0 >B3KL04.1 B3KL04_9BACI ATP-dependent protease La Length = 778 Score = 921 bits (2380), Expect = 0.0, Method: Compositional matrix adjust. Identities = 441/517 (85%), Positives = 487/517 (94%) Query: 1 MEEKELPERVKEKIEKEIDRLEKMPASSAEGGVIRNYVDMLLSLPWTESTEDDLDILKAE 60 ++E ELPERV+EK+EKEIDRLEKMPASSAEGGVIRNYVD LL+LPWT TEDDLDI+KAE Sbjct: 258 LQELELPERVQEKVEKEIDRLEKMPASSAEGGVIRNYVDWLLALPWTNKTEDDLDIVKAE 317 Query: 61 QVLDADHYGLEKPKERVLEYLAVQKLVKKLKGPILCLVGPPGVGKTSLARSIARSLNRKF 120 QVLD DHYGLEKPKERVLEYLAVQKLVKK+KGPILCLVGPPGVGKTSLARSIARSL RKF Sbjct: 318 QVLDEDHYGLEKPKERVLEYLAVQKLVKKMKGPILCLVGPPGVGKTSLARSIARSLERKF 377 Query: 121 VRISLGGVRDEAEIRGHRRTYVGAMPGRIIQGMKTAGSINPVFLLDEIDKMAADFRGDPS 180 VR+SLGGVRDEAEIRGHRRTYVGAMPGRIIQGMKTAGS+NPVFLLDEIDKMA+DFRGDPS Sbjct: 378 VRVSLGGVRDEAEIRGHRRTYVGAMPGRIIQGMKTAGSMNPVFLLDEIDKMASDFRGDPS 437 Query: 181 AALLEVLDPEQNNTFSDHFVELPFDLSNVMFVTTANTVHNIPRPLLDRMEMLFIPGYTEL 240 +ALLEVLDPEQNNTFSDHFVE+PFDLSNVMFVTTAN +HNIPRPLLDRME+L IPGYTEL Sbjct: 438 SALLEVLDPEQNNTFSDHFVEIPFDLSNVMFVTTANVLHNIPRPLLDRMEVLNIPGYTEL 497 Query: 241 EKLQIASRYLLPKQRKNHGLEEGQLSIEDDTLLKIVREYTRESGVRNLEQQIAALCRKAA 300 EKLQIA+RYLLPKQ+ HGLE QL ++++ L+K++REYTRESGVRNLEQQ+AALCRKAA Sbjct: 498 EKLQIANRYLLPKQKSEHGLEPEQLILDEEALMKVIREYTRESGVRNLEQQVAALCRKAA 557 Query: 301 KIIVSGEKEQVSILPAEVKDYLGASKYRYGMAELEDQIGTVTGLAWTEVGGDTLLIEVTV 360 K IV+ + E + I A++KDYLG K+RYGMAELEDQ+GTVTGLAWTEVGG+TL IEVTV Sbjct: 558 KQIVTQQSESIEIKAADIKDYLGIPKFRYGMAELEDQVGTVTGLAWTEVGGETLTIEVTV 617 Query: 361 VQGTGKLILTGQLGDVMKESAQAAFSYTRSKAEELGLAPDFYEKNDIHIHIPEGAIPKDG 420 V GTGKL LTG+LGDVMKESAQAAFS+TRSKA ELG+ PDF+EK D+HIHIPEGAIPKDG Sbjct: 618 VPGTGKLTLTGKLGDVMKESAQAAFSFTRSKAVELGIDPDFHEKLDVHIHIPEGAIPKDG 677 Query: 421 PSAGITIATALISALTKRYVSKDVAMTGEITLRGRVLPIGGLKEKSLAAHRAGYKKILLP 480 PSAGITIATALIS+LTKR+V++DVAMTGEITLRGRVLPIGGLKEKSLAAHRAGYKKILLP Sbjct: 678 PSAGITIATALISSLTKRHVARDVAMTGEITLRGRVLPIGGLKEKSLAAHRAGYKKILLP 737 Query: 481 KDNERDLKDIPESVRSDVEFVPVSHMDQVLKHALVEH 517 KDNERDL+DIP+SV++DVEFVPVSHMDQVL+HALVE Sbjct: 738 KDNERDLRDIPDSVKNDVEFVPVSHMDQVLEHALVEQ 774 >Q84FG5.1 Q84FG5_9BACL ATP-dependent protease La Length = 779 Score = 781 bits (2016), Expect = 0.0, Method: Compositional matrix adjust. Identities = 364/514 (70%), Positives = 441/514 (85%) Query: 1 MEEKELPERVKEKIEKEIDRLEKMPASSAEGGVIRNYVDMLLSLPWTESTEDDLDILKAE 60 +E+ + PER+K KIEKE++RLEKMP +SAEG VIR Y+D LLSLPWT T D+LDI AE Sbjct: 257 LEKSDAPERIKNKIEKELERLEKMPTTSAEGAVIRTYIDTLLSLPWTRRTVDNLDIHHAE 316 Query: 61 QVLDADHYGLEKPKERVLEYLAVQKLVKKLKGPILCLVGPPGVGKTSLARSIARSLNRKF 120 QVL+ DHYGLEKPKERVLEYLAVQKLV ++GPILCLVGPPGVGKTSLARSIAR+L R+F Sbjct: 317 QVLNEDHYGLEKPKERVLEYLAVQKLVNSMRGPILCLVGPPGVGKTSLARSIARALEREF 376 Query: 121 VRISLGGVRDEAEIRGHRRTYVGAMPGRIIQGMKTAGSINPVFLLDEIDKMAADFRGDPS 180 VRISLGGVRDEAEIRGHRRTYVGA+PGRIIQGMK AG+INPVFLLDEIDK+A+DFRGDP+ Sbjct: 377 VRISLGGVRDEAEIRGHRRTYVGALPGRIIQGMKQAGTINPVFLLDEIDKLASDFRGDPA 436 Query: 181 AALLEVLDPEQNNTFSDHFVELPFDLSNVMFVTTANTVHNIPRPLLDRMEMLFIPGYTEL 240 +ALLEVLDP QN+ FSDH++E +DL+NVMF+TTAN+ H IPRPLLDRME++ I GYTEL Sbjct: 437 SALLEVLDPNQNDKFSDHYIEETYDLTNVMFITTANSTHTIPRPLLDRMEVISIAGYTEL 496 Query: 241 EKLQIASRYLLPKQRKNHGLEEGQLSIEDDTLLKIVREYTRESGVRNLEQQIAALCRKAA 300 EKL I YLLPKQ + HGL +L + ++ +LK++R+YTRE+GVRNL ++ A +CRKAA Sbjct: 497 EKLHIMRDYLLPKQMEEHGLGRDKLQMNEEAMLKVIRQYTREAGVRNLNREAANICRKAA 556 Query: 301 KIIVSGEKEQVSILPAEVKDYLGASKYRYGMAELEDQIGTVTGLAWTEVGGDTLLIEVTV 360 ++IVSGEK++V + P V+ LG +YRYG+AE EDQ+G VTGLAWT+ GGDTL +EV++ Sbjct: 557 RLIVSGEKKRVVVTPKTVESLLGKPRYRYGLAEREDQVGAVTGLAWTQAGGDTLNVEVSI 616 Query: 361 VQGTGKLILTGQLGDVMKESAQAAFSYTRSKAEELGLAPDFYEKNDIHIHIPEGAIPKDG 420 + G GKL LTGQLGDVMKESAQAAFSY RS+A + P+F+EKNDIHIH+PEGAIPKDG Sbjct: 617 LPGKGKLTLTGQLGDVMKESAQAAFSYIRSRAAAWNIDPEFHEKNDIHIHVPEGAIPKDG 676 Query: 421 PSAGITIATALISALTKRYVSKDVAMTGEITLRGRVLPIGGLKEKSLAAHRAGYKKILLP 480 PSAGITIATAL+SALT V K+V MTGEITLRGRVLPIGGLKEK+L+AHRAG ++LP Sbjct: 677 PSAGITIATALVSALTGIPVRKEVGMTGEITLRGRVLPIGGLKEKALSAHRAGLTTVILP 736 Query: 481 KDNERDLKDIPESVRSDVEFVPVSHMDQVLKHAL 514 K+NE+D++DIPESVR +++ + V HMD+VL+HAL Sbjct: 737 KENEKDIEDIPESVRKELKLITVEHMDEVLRHAL 770 >P36772.1 LON_BRECH ATP-dependent protease La EC=3.4.21.53 Length = 779 Score = 778 bits (2009), Expect = 0.0, Method: Compositional matrix adjust. Identities = 364/517 (70%), Positives = 445/517 (86%) Query: 1 MEEKELPERVKEKIEKEIDRLEKMPASSAEGGVIRNYVDMLLSLPWTESTEDDLDILKAE 60 +E+ + PER+K KIEKE++RLEKMP++SAEG VIR Y+D L +LPWT++TED+LDI AE Sbjct: 257 LEKSDAPERIKAKIEKELERLEKMPSTSAEGSVIRTYIDTLFALPWTKTTEDNLDIKHAE 316 Query: 61 QVLDADHYGLEKPKERVLEYLAVQKLVKKLKGPILCLVGPPGVGKTSLARSIARSLNRKF 120 +VLD DHYGLEKPKERVLEYLAVQKLV ++GPILCLVGPPGVGKTSLARS+AR+L R+F Sbjct: 317 EVLDEDHYGLEKPKERVLEYLAVQKLVNSMRGPILCLVGPPGVGKTSLARSVARALGREF 376 Query: 121 VRISLGGVRDEAEIRGHRRTYVGAMPGRIIQGMKTAGSINPVFLLDEIDKMAADFRGDPS 180 VRISLGGVRDEAEIRGHRRTYVGA+PGRIIQGMK AG+INPVFLLDEIDK+A+DFRGDP+ Sbjct: 377 VRISLGGVRDEAEIRGHRRTYVGALPGRIIQGMKQAGTINPVFLLDEIDKLASDFRGDPA 436 Query: 181 AALLEVLDPEQNNTFSDHFVELPFDLSNVMFVTTANTVHNIPRPLLDRMEMLFIPGYTEL 240 +ALLEVLDP QN+ FSDH++E +DL+NVMF+TTAN++ IPRPLLDRME++ I GYTEL Sbjct: 437 SALLEVLDPNQNDKFSDHYIEETYDLTNVMFITTANSLDTIPRPLLDRMEVISISGYTEL 496 Query: 241 EKLQIASRYLLPKQRKNHGLEEGQLSIEDDTLLKIVREYTRESGVRNLEQQIAALCRKAA 300 EKL I YLLPKQ ++HGL + +L + +D +LK+VR YTRE+GVRNL ++ A +CRKAA Sbjct: 497 EKLNILRGYLLPKQMEDHGLGKDKLQMNEDAMLKLVRLYTREAGVRNLNREAANVCRKAA 556 Query: 301 KIIVSGEKEQVSILPAEVKDYLGASKYRYGMAELEDQIGTVTGLAWTEVGGDTLLIEVTV 360 KIIV GEK++V + ++ LG +YRYG+AE +DQ+G+VTGLAWT+ GGDTL +EV++ Sbjct: 557 KIIVGGEKKRVVVTAKTLEALLGKPRYRYGLAEKKDQVGSVTGLAWTQAGGDTLNVEVSI 616 Query: 361 VQGTGKLILTGQLGDVMKESAQAAFSYTRSKAEELGLAPDFYEKNDIHIHIPEGAIPKDG 420 + G GKL LTGQLGDVMKESAQAAFSY RS+A E G+ P+F+EKNDIHIH+PEGAIPKDG Sbjct: 617 LAGKGKLTLTGQLGDVMKESAQAAFSYIRSRASEWGIDPEFHEKNDIHIHVPEGAIPKDG 676 Query: 421 PSAGITIATALISALTKRYVSKDVAMTGEITLRGRVLPIGGLKEKSLAAHRAGYKKILLP 480 PSAGIT+ATAL+SALT V K+V MTGEITLRGRVLPIGGLKEK ++AHRAG I+LP Sbjct: 677 PSAGITMATALVSALTGIPVKKEVGMTGEITLRGRVLPIGGLKEKCMSAHRAGLTTIILP 736 Query: 481 KDNERDLKDIPESVRSDVEFVPVSHMDQVLKHALVEH 517 KDNE+D++DIPESVR + F PV H+D+VL+HAL + Sbjct: 737 KDNEKDIEDIPESVREALTFYPVEHLDEVLRHALTKQ 773 >C5D5L2.1 C5D5L2_9BACI ATP-dependent protease La EC=3.4.21.53 Length = 774 Score = 777 bits (2007), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/515 (71%), Positives = 445/515 (86%) Query: 1 MEEKELPERVKEKIEKEIDRLEKMPASSAEGGVIRNYVDMLLSLPWTESTEDDLDILKAE 60 +E +P VKE KE+DR EK+PA+SAE VIRNY+D L++LPW+ TED DI +AE Sbjct: 256 IEAAGMPSHVKETALKELDRYEKIPATSAESAVIRNYLDWLIALPWSTQTEDIHDIKRAE 315 Query: 61 QVLDADHYGLEKPKERVLEYLAVQKLVKKLKGPILCLVGPPGVGKTSLARSIARSLNRKF 120 +L+ DHYGLEK KERVLE+L+VQ+L K LKGPILCL GPPGVGKTSLARSIA+SLNR+F Sbjct: 316 AILNEDHYGLEKVKERVLEFLSVQQLTKSLKGPILCLAGPPGVGKTSLARSIAKSLNRRF 375 Query: 121 VRISLGGVRDEAEIRGHRRTYVGAMPGRIIQGMKTAGSINPVFLLDEIDKMAADFRGDPS 180 VRISLGGVRDE+EIRGHRRTYVGAMPGRIIQGMK AG+INPVFLLDEIDKM++DFRGDPS Sbjct: 376 VRISLGGVRDESEIRGHRRTYVGAMPGRIIQGMKKAGTINPVFLLDEIDKMSSDFRGDPS 435 Query: 181 AALLEVLDPEQNNTFSDHFVELPFDLSNVMFVTTANTVHNIPRPLLDRMEMLFIPGYTEL 240 AALLEVLDPEQN+TFSDH++E P+DLS VMF+ TAN + IP+PLLDRME++ IPGYTE+ Sbjct: 436 AALLEVLDPEQNHTFSDHYIEEPYDLSKVMFIATANNLATIPQPLLDRMEIITIPGYTEV 495 Query: 241 EKLQIASRYLLPKQRKNHGLEEGQLSIEDDTLLKIVREYTRESGVRNLEQQIAALCRKAA 300 EKLQIA R+LLPKQ K HGL++ L + DD ++ I+R YTRE+GVR LE+QIAA+CRKAA Sbjct: 496 EKLQIAKRHLLPKQLKEHGLKKSSLQVRDDAMMSIIRYYTREAGVRELERQIAAICRKAA 555 Query: 301 KIIVSGEKEQVSILPAEVKDYLGASKYRYGMAELEDQIGTVTGLAWTEVGGDTLLIEVTV 360 ++IVS EK++V I ++++LG KYRYG AELEDQ+G TGLA+T GGDTL IEV++ Sbjct: 556 RLIVSEEKKRVIITEKNIEEFLGKRKYRYGQAELEDQVGVATGLAYTAFGGDTLSIEVSL 615 Query: 361 VQGTGKLILTGQLGDVMKESAQAAFSYTRSKAEELGLAPDFYEKNDIHIHIPEGAIPKDG 420 G GKL+LTG+LGDVMKESAQAAFSY RS+AE+LG+ +F+EK DIHIH+PEGA+PKDG Sbjct: 616 APGKGKLVLTGKLGDVMKESAQAAFSYVRSRAEQLGIDSEFHEKYDIHIHVPEGAVPKDG 675 Query: 421 PSAGITIATALISALTKRYVSKDVAMTGEITLRGRVLPIGGLKEKSLAAHRAGYKKILLP 480 PSAGITIATALISALT R V++ V MTGEITLRGRVLPIGGLKEK+L+AHRAG KK++LP Sbjct: 676 PSAGITIATALISALTGRPVNRFVGMTGEITLRGRVLPIGGLKEKTLSAHRAGLKKVILP 735 Query: 481 KDNERDLKDIPESVRSDVEFVPVSHMDQVLKHALV 515 KDNE+DL+DIP+ V++D++FV VSH+D+VL+HALV Sbjct: 736 KDNEKDLEDIPDVVKNDLQFVLVSHLDEVLQHALV 770 >C0ZAG5.1 C0ZAG5_BREBN ATP-dependent protease La EC=3.4.21.53 Length = 779 Score = 777 bits (2006), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/517 (69%), Positives = 446/517 (86%) Query: 1 MEEKELPERVKEKIEKEIDRLEKMPASSAEGGVIRNYVDMLLSLPWTESTEDDLDILKAE 60 +E+ + PER+K KIEKE++RLEKMPA+SAEG VIR Y+D L +LPWT++TED+LDI A+ Sbjct: 257 LEKSDAPERIKAKIEKELERLEKMPATSAEGSVIRTYIDTLFALPWTKTTEDNLDIHHAQ 316 Query: 61 QVLDADHYGLEKPKERVLEYLAVQKLVKKLKGPILCLVGPPGVGKTSLARSIARSLNRKF 120 QVLD DHYGL+KPKERVLEYLAVQKLV ++GPILCLVGPPGVGKTSLARS+AR++ R+F Sbjct: 317 QVLDEDHYGLDKPKERVLEYLAVQKLVNSMRGPILCLVGPPGVGKTSLARSVARAIGREF 376 Query: 121 VRISLGGVRDEAEIRGHRRTYVGAMPGRIIQGMKTAGSINPVFLLDEIDKMAADFRGDPS 180 VRISLGGVRDEAEIRGHRRTYVGA+PGRIIQGMK AG++NPVFLLDEIDK+A+DFRGDP+ Sbjct: 377 VRISLGGVRDEAEIRGHRRTYVGALPGRIIQGMKQAGTVNPVFLLDEIDKLASDFRGDPA 436 Query: 181 AALLEVLDPEQNNTFSDHFVELPFDLSNVMFVTTANTVHNIPRPLLDRMEMLFIPGYTEL 240 +ALLEVLDP QN+ FSDH++E +DL+NVMF+TTAN++ IPRPLLDRME++ I YTEL Sbjct: 437 SALLEVLDPNQNDKFSDHYIEETYDLTNVMFITTANSLDTIPRPLLDRMEVISISSYTEL 496 Query: 241 EKLQIASRYLLPKQRKNHGLEEGQLSIEDDTLLKIVREYTRESGVRNLEQQIAALCRKAA 300 EKL I YLLPKQ ++HGL + +L + DD +LK+VR YTRE+GVRNL ++ A +CRKAA Sbjct: 497 EKLNILRDYLLPKQMQDHGLGKDKLKMNDDAMLKLVRLYTREAGVRNLNREAANVCRKAA 556 Query: 301 KIIVSGEKEQVSILPAEVKDYLGASKYRYGMAELEDQIGTVTGLAWTEVGGDTLLIEVTV 360 K+IV GEK++V + ++ LG +YRYG+AE++DQ+G+VTGLAWT+ GGDTL +EV++ Sbjct: 557 KLIVGGEKKRVVVTVKTLETLLGKPRYRYGLAEIKDQVGSVTGLAWTQAGGDTLNVEVSI 616 Query: 361 VQGTGKLILTGQLGDVMKESAQAAFSYTRSKAEELGLAPDFYEKNDIHIHIPEGAIPKDG 420 + G GKL LTG+LGDVMKESAQAAFSY RS+AE+ G+ P F+EKNDIHIH PEGAIPKDG Sbjct: 617 LPGKGKLTLTGKLGDVMKESAQAAFSYIRSRAEQWGIDPAFHEKNDIHIHFPEGAIPKDG 676 Query: 421 PSAGITIATALISALTKRYVSKDVAMTGEITLRGRVLPIGGLKEKSLAAHRAGYKKILLP 480 PSAGIT+ATAL+SALTK V K+V MTGEITLRGRVLPIGGLKEK ++AHRAG I+LP Sbjct: 677 PSAGITMATALVSALTKIPVKKEVGMTGEITLRGRVLPIGGLKEKCMSAHRAGLTTIILP 736 Query: 481 KDNERDLKDIPESVRSDVEFVPVSHMDQVLKHALVEH 517 KDNE+D++DIPESVR ++ F PV H+D+VL+HAL + Sbjct: 737 KDNEKDIEDIPESVRGELTFYPVDHLDEVLRHALTKQ 773 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.316 0.135 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,138,522,813 Number of extensions: 134676694 Number of successful extensions: 578304 Number of sequences better than 1.0e-05: 2113 Number of HSP's gapped: 576103 Number of HSP's successfully gapped: 2323 Length of query: 530 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 389 Effective length of database: 1,732,333,088 Effective search space: 673877571232 Effective search space used: 673877571232 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 134 (56.2 bits)