BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0420.0038.p (339 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B0KBF1.1 B0KBF1_THEP3 Transcriptional regulator, LacI family 208 6e-52 B0K457.1 B0K457_THEPX Alanine racemase EC=5.1.1.1 206 4e-51 Q8R748.1 Q8R748_THETN Transcriptional regulator 204 1e-50 C5D6S4.1 C5D6S4_9BACI Transcriptional regulator, LacI family EC=... 199 4e-49 B7GLU4.1 B7GLU4_ANOFW Transcriptional regulator, LacI family (HT... 197 1e-48 >B0KBF1.1 B0KBF1_THEP3 Transcriptional regulator, LacI family Length = 337 Score = 208 bits (529), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 113/317 (35%), Positives = 191/317 (60%), Gaps = 3/317 (0%) Query: 1 MKVTITDIAIAAGVAKSTVSKVLNDSPKISQETKQKVREIMKQMNYTPSSIATGLARQSS 60 M VTI D+A A VA STVS+V+ D+P+IS+ETK++V + M+++ Y P++IA LA + + Sbjct: 1 MNVTIKDVAKRANVAPSTVSRVIADNPRISKETKERVWKAMEELGYYPNAIARSLASKVT 60 Query: 61 SNIGLLIDMSKSSEFLNQFFYNIIGGIESVIGSLKYELTIANVEHNHPDGHFLHRLVRSK 120 + +GL++ S F N FF ++ GI V KY+L ++ + + + +V+ K Sbjct: 61 NTLGLIMPRSTEEAFSNPFFPEVMRGISVVAHREKYDLLLSTSGNQEEEKEAVINMVKGK 120 Query: 121 RVDGLIANTSVLTEELCTRLNHLEFPYVSLGE-VAASGC-WVDFDNEAGGRMLTRHLLEE 178 RVDG+I +S T+EL L +FP+V +G+ + A G WVD DN ++ T +L++ Sbjct: 121 RVDGIILLSSRTTDELIPWLRDEKFPFVVIGKPLDAKGVYWVDNDNIGASKLATNYLIKH 180 Query: 179 GYSAVAFIGGYEGDPLFIRRLEGCRQVLGQAGKPLRKEWIINGEAEEAFGYQAAKQLLLS 238 G+ +AFI G + + RL+G + L + G P ++E + E E GY+A ++L Sbjct: 181 GHREIAFISGSLEYVVSLDRLDGYKLALEENGIPFKRELVEQDEFSEDGGYRAMMRILER 240 Query: 239 ETPPDSVICMSNFAAYGVLLAARELGVKVPTQLGIATFDDYPLSRYTSPPLTSLNLDTFH 298 E P +V+ + A+GV+ AA + G +VP + I F++ PLS + +PPLT++++ TF Sbjct: 241 EK-PTAVVVTDDVMAFGVIRAAIDKGYRVPEDISIVGFNNIPLSAFANPPLTTIDISTFD 299 Query: 299 LGVSAGKLLMERIGGKN 315 LG+ + +LL+ R+ K+ Sbjct: 300 LGIKSAELLIARLKQKD 316 >B0K457.1 B0K457_THEPX Alanine racemase EC=5.1.1.1 Length = 337 Score = 206 bits (523), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 113/316 (35%), Positives = 189/316 (59%), Gaps = 3/316 (0%) Query: 1 MKVTITDIAIAAGVAKSTVSKVLNDSPKISQETKQKVREIMKQMNYTPSSIATGLARQSS 60 M VTI D+A A VA STVS+V+ D+P+IS+ETK++V + M+++ Y P++IA LA + + Sbjct: 1 MNVTIKDVAKRANVAPSTVSRVIADNPRISKETKERVWKAMEELGYYPNAIARSLASKVT 60 Query: 61 SNIGLLIDMSKSSEFLNQFFYNIIGGIESVIGSLKYELTIANVEHNHPDGHFLHRLVRSK 120 + +GL++ S F N FF ++ GI V KY+L ++ + + + +V+ K Sbjct: 61 NTLGLIMPRSTEEAFSNPFFPEVMRGISVVAHREKYDLLLSTSGNQEEEKEAVINMVKGK 120 Query: 121 RVDGLIANTSVLTEELCTRLNHLEFPYVSLGE-VAASGC-WVDFDNEAGGRMLTRHLLEE 178 RVDG+I +S T+EL L +FP+V +G+ + A G WVD DN ++ T +L++ Sbjct: 121 RVDGIILLSSRTTDELIPWLRDEKFPFVVIGKPLDAKGVYWVDNDNIGASKLATNYLIKH 180 Query: 179 GYSAVAFIGGYEGDPLFIRRLEGCRQVLGQAGKPLRKEWIINGEAEEAFGYQAAKQLLLS 238 G+ +AFI G + + RL+G + L + G P ++E E E GY+A ++L Sbjct: 181 GHREIAFISGSLEYVVSLDRLDGYKLALEENGIPFKRELAEQDEFSEDGGYRAMMRILER 240 Query: 239 ETPPDSVICMSNFAAYGVLLAARELGVKVPTQLGIATFDDYPLSRYTSPPLTSLNLDTFH 298 E P +V+ + A+GV+ AA + G +VP + I F++ PLS + +PPLT++++ TF Sbjct: 241 EK-PTAVVVTDDVMAFGVIRAAIDKGYRVPEDISIVGFNNIPLSAFANPPLTTIDISTFD 299 Query: 299 LGVSAGKLLMERIGGK 314 LG+ + +LL+ R+ K Sbjct: 300 LGIKSAELLIARLKQK 315 >Q8R748.1 Q8R748_THETN Transcriptional regulator Length = 341 Score = 204 bits (519), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 112/316 (35%), Positives = 187/316 (59%), Gaps = 3/316 (0%) Query: 1 MKVTITDIAIAAGVAKSTVSKVLNDSPKISQETKQKVREIMKQMNYTPSSIATGLARQSS 60 M VTI D+A A VA STVS+V+ DSP+IS+ETK++V + M+++ Y P++IA LA + + Sbjct: 5 MNVTIKDVAKRANVAPSTVSRVIADSPRISKETKERVWKAMEELGYYPNAIARSLASKVT 64 Query: 61 SNIGLLIDMSKSSEFLNQFFYNIIGGIESVIGSLKYELTIANVEHNHPDGHFLHRLVRSK 120 + +GL++ S F N FF ++ GI V KY+L ++ + + + R+V+ K Sbjct: 65 NTLGLIMPRSTEEAFSNPFFPEVMRGISVVAHREKYDLLLSTSGNKEEEKEAVIRMVKGK 124 Query: 121 RVDGLIANTSVLTEELCTRLNHLEFPYVSLGE-VAASGC-WVDFDNEAGGRMLTRHLLEE 178 RVDG+I +S T+EL L +FP+V +G+ + A G WVD DN ++ T +L++ Sbjct: 125 RVDGIILLSSRTTDELIPWLRDEKFPFVVIGKPLDARGVYWVDNDNIGASKLATNYLIKH 184 Query: 179 GYSAVAFIGGYEGDPLFIRRLEGCRQVLGQAGKPLRKEWIINGEAEEAFGYQAAKQLLLS 238 G+ +AFI G + + RL+G + L + G ++E + E E GY+A + +L Sbjct: 185 GHREIAFISGSLEYVVSLDRLDGYKLALEENGLTFKRELVEQEEFSEDGGYRAMMK-ILE 243 Query: 239 ETPPDSVICMSNFAAYGVLLAARELGVKVPTQLGIATFDDYPLSRYTSPPLTSLNLDTFH 298 P V+ + A+GV+ A + G +VP + I F++ PLS + +PPLT++++ TF Sbjct: 244 RAKPTGVVVTDDVMAFGVIRATIDKGFRVPEDISIVGFNNIPLSAFANPPLTTIDISTFE 303 Query: 299 LGVSAGKLLMERIGGK 314 LG+ + +LL+ R+ K Sbjct: 304 LGIKSAELLIARLKQK 319 >C5D6S4.1 C5D6S4_9BACI Transcriptional regulator, LacI family EC=5.1.1.1 Length = 341 Score = 199 bits (505), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 113/318 (35%), Positives = 181/318 (56%), Gaps = 3/318 (0%) Query: 1 MKVTITDIAIAAGVAKSTVSKVLNDSPKISQETKQKVREIMKQMNYTPSSIATGLARQSS 60 M VTI D+A A VA STVS+V+ DSP+IS++TK+KVRE MK++ Y P+ IA LA Q++ Sbjct: 1 MTVTIKDVAKRANVAPSTVSRVIADSPRISEKTKRKVREAMKELGYHPNFIARSLANQAT 60 Query: 61 SNIGLLIDMSKSSEFLNQFFYNIIGGIESVIGSLKYELTIANVEHNHPDGHFLHRLVRSK 120 IG+++ + N FF +I GI KY L ++ E + +++ + Sbjct: 61 QVIGIVMPSAAEQALQNPFFPEVIRGISKAAHEKKYALQMSTGEKEVEIYEGVVDMLQGR 120 Query: 121 RVDGLIANTSVLTEELCTRLNHLEFPYVSLG---EVAASGCWVDFDNEAGGRMLTRHLLE 177 RVDG+I S + ++L L +FP+V +G + A VD DN G+ T +L+ Sbjct: 121 RVDGVILLYSRIDDKLMKYLQKNKFPFVVIGKPHQKAEQITHVDNDNYLAGKEATEYLIA 180 Query: 178 EGYSAVAFIGGYEGDPLFIRRLEGCRQVLGQAGKPLRKEWIINGEAEEAFGYQAAKQLLL 237 G+ +AF+GG + + + RL G L +AG P R+++I++ E + G +A K+LL Sbjct: 181 RGHERIAFVGGNKQYLVTVDRLSGYEAALKEAGLPYREDYIMHEEFLQEGGQEAMKELLS 240 Query: 238 SETPPDSVICMSNFAAYGVLLAARELGVKVPTQLGIATFDDYPLSRYTSPPLTSLNLDTF 297 PP +++ + A GVL E+ ++VP + I +F++ L+ + PPLTS+++ F Sbjct: 241 LADPPTALVVADDLMALGVLKTLDEMNLRVPDDISIVSFNNTLLAEMSRPPLTSVDIHIF 300 Query: 298 HLGVSAGKLLMERIGGKN 315 LG A K L+E+IG N Sbjct: 301 QLGYEATKSLIEKIGNPN 318 >B7GLU4.1 B7GLU4_ANOFW Transcriptional regulator, LacI family (HTH and periplasmic-binding domains) Length = 344 Score = 197 bits (500), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 116/318 (36%), Positives = 179/318 (56%), Gaps = 3/318 (0%) Query: 1 MKVTITDIAIAAGVAKSTVSKVLNDSPKISQETKQKVREIMKQMNYTPSSIATGLARQSS 60 M VTI D+A A VA STVS+V+ DSP+IS++TK+KVRE MK++ Y P+ IA LA +S+ Sbjct: 1 MTVTIKDVAKRANVAPSTVSRVIADSPRISEKTKKKVREAMKELGYHPNFIARSLANKST 60 Query: 61 SNIGLLIDMSKSSEFLNQFFYNIIGGIESVIGSLKYELTIANVEHNHPDGHFLHRLVRSK 120 IGL++ S F N FF +I GI + +Y L ++ E + +V+ K Sbjct: 61 QVIGLVMPSSADKAFQNPFFPEVIRGISKAVHDRQYALQLSTGETEAEIYEGVVHMVQGK 120 Query: 121 RVDGLIANTSVLTEELCTRLNHLEFPYVSLGEV---AASGCWVDFDNEAGGRMLTRHLLE 177 RVDG+I S +++ T L + P+V +G+ A VD DN R T +L+E Sbjct: 121 RVDGVILLYSRANDKIMTYLQKEDVPFVVIGKPHKRAEEITHVDNDNVRAAREATEYLIE 180 Query: 178 EGYSAVAFIGGYEGDPLFIRRLEGCRQVLGQAGKPLRKEWIINGEAEEAFGYQAAKQLLL 237 G+ +AF+GG + + RL G + L AG RK++I++ E + G +A K+LL Sbjct: 181 LGHERIAFVGGNVNLIVTMDRLRGYEKALKSAGLAYRKDYIVHEEFLKEGGQEAMKELLS 240 Query: 238 SETPPDSVICMSNFAAYGVLLAARELGVKVPTQLGIATFDDYPLSRYTSPPLTSLNLDTF 297 PP +++ + A GVL E+G+ VP + I +F++ LS + PPLTS+++ F Sbjct: 241 LAEPPTALVVADDLMALGVLNTLAEMGLSVPGDVSIVSFNNVLLSEISRPPLTSVDIHIF 300 Query: 298 HLGVSAGKLLMERIGGKN 315 LG A + L+++I N Sbjct: 301 QLGFEAARNLIQQIENPN 318 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,875,115,624 Number of extensions: 76114626 Number of successful extensions: 233028 Number of sequences better than 1.0e-05: 8613 Number of HSP's gapped: 219651 Number of HSP's successfully gapped: 8637 Length of query: 339 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 203 Effective length of database: 1,779,438,163 Effective search space: 361225947089 Effective search space used: 361225947089 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)