BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0420.0026.p (327 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K747.1 B3K747_9BACI Response regulator receiver 387 e-106 Q5WKN6.1 Q5WKN6_BACSK Two-component response regulator 353 9e-96 C4CR27.1 C4CR27_9CHLR Response regulator with CheY-like receiver... 266 2e-69 B8FPQ5.1 B8FPQ5_DESHD Two component transcriptional regulator, w... 228 7e-58 Q2RMD0.1 Q2RMD0_MOOTA Two component transcriptional regulator, w... 216 2e-54 >B3K747.1 B3K747_9BACI Response regulator receiver Length = 228 Score = 387 bits (994), Expect = e-106, Method: Compositional matrix adjust. Identities = 181/227 (79%), Positives = 210/227 (92%) Query: 100 MSEISTILVVDDDQSIVELLRDFLENENFHVITACDSAEALALFQQSSIHCIVLDIMMPG 159 MS +TILVVDDDQSIVELLRDFLEN++FHV TACD+ EA A+FQQ I C+VLDIMMPG Sbjct: 1 MSGDNTILVVDDDQSIVELLRDFLENDSFHVKTACDAEEAWAIFQQHPIQCMVLDIMMPG 60 Query: 160 QNGFELCRQIRAESNIPILFLSARSDDVDKIRGLTLGGDDYIVKSASPGEIVARVKAVLR 219 QNGFELCR+IRAES +PILFLSARSDDVDKIRGLTLGGDDYIVK+ASP EIVARVKAVLR Sbjct: 61 QNGFELCRRIRAESPVPILFLSARSDDVDKIRGLTLGGDDYIVKTASPAEIVARVKAVLR 120 Query: 220 RFASQKQMDGRILDYGRIKLNLSTREVIVEGKNVDLTPREYELLRLFVEHPRHVFSYEQL 279 R A+++ M+ R+LDYGR++LNLSTREV+V+G NV LTP+E+ELLR+F EHPRHVF+Y+QL Sbjct: 121 RSATRRPMEERVLDYGRLRLNLSTREVVVDGNNVVLTPKEFELLRVFAEHPRHVFTYDQL 180 Query: 280 IVKFWNGVGDKHTIRVHLSRLREKIESDPNQPKYLVNVWGVGYRFEG 326 + KFW+GVGD+HTIRVHLSRLREKIE+DPNQP++LVNVWGVGYRFEG Sbjct: 181 LAKFWDGVGDRHTIRVHLSRLREKIEADPNQPQFLVNVWGVGYRFEG 227 >Q5WKN6.1 Q5WKN6_BACSK Two-component response regulator Length = 227 Score = 353 bits (907), Expect = 9e-96, Method: Compositional matrix adjust. Identities = 163/223 (73%), Positives = 199/223 (89%) Query: 105 TILVVDDDQSIVELLRDFLENENFHVITACDSAEALALFQQSSIHCIVLDIMMPGQNGFE 164 TILVVDDDQSI +LLRDFLEN++F+V+TA ++ EA FQQS++ C++LDIMMPG+NGF Sbjct: 5 TILVVDDDQSIADLLRDFLENDHFYVLTASNTEEAWEAFQQSAVDCLILDIMMPGENGFA 64 Query: 165 LCRQIRAESNIPILFLSARSDDVDKIRGLTLGGDDYIVKSASPGEIVARVKAVLRRFASQ 224 CR+IRA+S++PILFLSARS DVDKIRGLTLGGDDYIVK+ASPGEIVARVKAVLRR AS Sbjct: 65 FCRRIRAKSDVPILFLSARSADVDKIRGLTLGGDDYIVKTASPGEIVARVKAVLRRSASN 124 Query: 225 KQMDGRILDYGRIKLNLSTREVIVEGKNVDLTPREYELLRLFVEHPRHVFSYEQLIVKFW 284 + IL++G + LNL+TRE+ V+GKNV LTP+EYELL+LF+EHPRHVFSY+QL+ K W Sbjct: 125 QPPTETILEFGHLTLNLTTRELAVDGKNVMLTPKEYELLQLFLEHPRHVFSYDQLLDKLW 184 Query: 285 NGVGDKHTIRVHLSRLREKIESDPNQPKYLVNVWGVGYRFEGG 327 +GVGDKHT+RVHLSRLREKIE++PN P+Y+VNVWG+GYRFEGG Sbjct: 185 DGVGDKHTVRVHLSRLREKIEANPNDPQYIVNVWGIGYRFEGG 227 >C4CR27.1 C4CR27_9CHLR Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain Length = 225 Score = 266 bits (680), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 119/221 (53%), Positives = 164/221 (74%) Query: 106 ILVVDDDQSIVELLRDFLENENFHVITACDSAEALALFQQSSIHCIVLDIMMPGQNGFEL 165 +L+VDD++ IV L+RDFLE E + V+ A D AL + + C++LD+MMPG +G+++ Sbjct: 1 MLIVDDEEDIVALMRDFLEAEGYAVLAAYDGPTALRTLEHEPVDCVLLDVMMPGPSGYDV 60 Query: 166 CRQIRAESNIPILFLSARSDDVDKIRGLTLGGDDYIVKSASPGEIVARVKAVLRRFASQK 225 R+IR ++P+LFL+AR +D DKIRGL LG DD+IVKSA+PGE+VAR+KAVLRR+ + Sbjct: 61 LRRIRENRDVPVLFLTARQEDHDKIRGLGLGADDFIVKSATPGEVVARIKAVLRRYRRGE 120 Query: 226 QMDGRILDYGRIKLNLSTREVIVEGKNVDLTPREYELLRLFVEHPRHVFSYEQLIVKFWN 285 +LD+GR+ +++ EV V+GK V LT RE+ELL+LF EHPR VF+ EQL + W Sbjct: 121 PAPRAVLDFGRLVIDVQAHEVRVDGKPVQLTAREFELLQLFAEHPRQVFTREQLFQRLWG 180 Query: 286 GVGDKHTIRVHLSRLREKIESDPNQPKYLVNVWGVGYRFEG 326 GD+HT+ VH+ RLREKIE DP P+Y+V VWGVGYRF+G Sbjct: 181 EFGDRHTVTVHIGRLREKIEEDPANPRYIVTVWGVGYRFDG 221 >B8FPQ5.1 B8FPQ5_DESHD Two component transcriptional regulator, winged helix family Length = 233 Score = 228 bits (580), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 109/226 (48%), Positives = 153/226 (67%), Gaps = 4/226 (1%) Query: 106 ILVVDDDQSIVELLRDFLENENFHVITACDSAEALALFQQSSIHCIVLDIMMPGQNGFEL 165 IL+ DD+ + EL++DFL +E + + A D EAL LF+ + ++LDIMMPG +G E+ Sbjct: 6 ILIADDEVELAELVKDFLSDEQYEALVARDGHEALELFRMNQPQLVILDIMMPGLDGMEV 65 Query: 166 CRQIRAESNIPILFLSARSDDVDKIRGLTLGGDDYIVKSASPGEIVARVKAVLRRF--AS 223 CR+IRAESN+PI+ LSA+ +VDKI GL LG DDYIVK SPGE+VARVKA LRRF ++ Sbjct: 66 CRRIRAESNVPIIMLSAKKAEVDKILGLGLGADDYIVKPFSPGEVVARVKAQLRRFKMSA 125 Query: 224 QKQMDGRILDYGRIKLNLSTREVIVEGKNVDLTPREYELLRLFVEHPRHVFSYEQLIVKF 283 + R+L Y +++++ E + G+ ++LT +E+ELLR HP V + EQ+ Sbjct: 126 VPEPKTRLLSYSGLEIDVQGYEAALAGRPLELTTKEFELLRFLALHPNQVLTREQIFANV 185 Query: 284 W--NGVGDKHTIRVHLSRLREKIESDPNQPKYLVNVWGVGYRFEGG 327 W N GD +T+ VH+ +LREKIESD P ++ VWGVGY+F GG Sbjct: 186 WGFNESGDLNTVTVHIKKLREKIESDLANPTFIKTVWGVGYKFSGG 231 >Q2RMD0.1 Q2RMD0_MOOTA Two component transcriptional regulator, winged helix family Length = 229 Score = 216 bits (551), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 108/227 (47%), Positives = 154/227 (67%), Gaps = 2/227 (0%) Query: 100 MSEISTILVVDDDQSIVELLRDFLENENFHVITACDSAEALALFQQSSIHCIVLDIMMPG 159 M ++ ILVVDD+ +IVEL++ LE F ITA D AEAL + I+LD+M+P Sbjct: 1 MIKLPKILVVDDEPAIVELVKFNLEQAGFTTITASDGAEALQKAEAEKPDLIILDVMLPK 60 Query: 160 QNGFELCRQIRAESNIPILFLSARSDDVDKIRGLTLGGDDYIVKSASPGEIVARVKAVLR 219 +GFE+CR +RA ++PIL L+AR ++VD++ GL LG DDY+ K SP E+VARV+A+LR Sbjct: 61 VDGFEVCRSLRARGSMPILMLTARREEVDRVLGLELGADDYLTKPFSPRELVARVRAILR 120 Query: 220 RFASQKQMDGRILDYGRIKLNLSTREVIVEGKNVDLTPREYELLRLFVEHPRHVFSYEQL 279 R A ++Q + I+ G + +N ++ V V GK VDLT +EY+LL+L E+ VFS E L Sbjct: 121 RVAEKQQQNDGIITVGDLVINPASHLVTVRGKPVDLTLKEYQLLQLLAENRGRVFSREAL 180 Query: 280 IVKFWNG--VGDKHTIRVHLSRLREKIESDPNQPKYLVNVWGVGYRF 324 + + W G GD TI VH+ LREKIE++P+ P+Y++ V GVGY+F Sbjct: 181 LERLWEGEYYGDTRTIDVHIRHLREKIEANPSNPRYIITVRGVGYKF 227 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.138 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,898,900,042 Number of extensions: 74660975 Number of successful extensions: 283058 Number of sequences better than 1.0e-05: 25162 Number of HSP's gapped: 255686 Number of HSP's successfully gapped: 25294 Length of query: 327 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 191 Effective length of database: 1,779,438,163 Effective search space: 339872689133 Effective search space used: 339872689133 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 131 (55.1 bits)