BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0420.0025.p (443 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K746.1 B3K746_9BACI Sensor protein EC=2.7.13.3 600 e-169 Q5WKN7.1 Q5WKN7_BACSK Sensor protein EC=2.7.13.3 552 e-155 C4CR26.1 C4CR26_9CHLR Signal transduction histidine kinase, COG0642 312 5e-83 Q67RL7.1 Q67RL7_SYMTH Sensor protein EC=2.7.13.3 180 2e-43 C2NP30.1 C2NP30_BACCE Putative uncharacterized protein 158 1e-36 >B3K746.1 B3K746_9BACI Sensor protein EC=2.7.13.3 Length = 456 Score = 600 bits (1547), Expect = e-169, Method: Compositional matrix adjust. Identities = 280/414 (67%), Positives = 334/414 (80%) Query: 26 VTSHYMETKTFSFTKSQPQNETLQRQLTEMIHLIETGSDKWMDPNWQNQLHKELRKAKMD 85 VT+H+METKT SF K + QNET+Q L+EMIH IE GS +W +P WQNQL L +AKMD Sbjct: 26 VTAHFMETKTLSFEKGRLQNETMQSNLSEMIHFIEAGSGQWTEPAWQNQLKTALHEAKMD 85 Query: 86 VAILSEYGQEIYRSNPERRGALSSTERFSIIEHGHLLGRVILYLPKSNTVQMISIFSGLL 145 V I S +E+YRSNPER G STERFS+I+ G LLGRV LYLP++N Q++S F+GLL Sbjct: 86 VLIQSAEERELYRSNPERSGTSLSTERFSVIKDGQLLGRVTLYLPRTNEKQVMSAFAGLL 145 Query: 146 LAFFVVGVEMRRFLLKPLENMSVAARQIAAGEWDVQLPLSRITEITEVRDGFEVMVKGLQ 205 LA +VG+ MRRF+LKPLE M AARQIA G+W +LP SR+TEI EVRDGFEVMVKGL+ Sbjct: 146 LAILIVGMGMRRFVLKPLEKMGNAARQIATGDWKARLPSSRVTEIAEVRDGFEVMVKGLE 205 Query: 206 KSYRKQVELEEERRFVIAAVAHDLRTPLFALRGYLDGLEQGIAQSPEKITKYVAVCKEKS 265 KSY+KQ ELE+ERRFVIAAVAHDLRTPLFALRGYLDGLEQGIAQSP+ + KYVAVCKEKS Sbjct: 206 KSYQKQAELEQERRFVIAAVAHDLRTPLFALRGYLDGLEQGIAQSPQMVAKYVAVCKEKS 265 Query: 266 AQLDRLVEDLFTFTKMEYWETKLNNKAVDLKLILRKSIDSLSPLAWQKHISISNHAADDC 325 QLDRLVEDLFTFT+MEY E +L+ VDL+ +++ S+DSL PLA KHI+ + DC Sbjct: 266 VQLDRLVEDLFTFTRMEYLEAELSRSLVDLRDVIQNSMDSLRPLAADKHIAFTAQFMGDC 325 Query: 326 IISGDTHLLERAMNNLLDNAVRHTPSNGEIVVQCYKDGNKVKFTIRDTGPGFSSEELQQV 385 ++SGDTHLLERAMNNL+DNAVRHTP +GEI VQC KDGN+++FTIRDTGPGFSSE+L++V Sbjct: 326 LLSGDTHLLERAMNNLMDNAVRHTPLDGEIAVQCCKDGNRIRFTIRDTGPGFSSEDLERV 385 Query: 386 FEPLYRGEESRNRXXXXXXXXXXISQRIIKRHGGELAAGNHPEGGAMLTGWIPV 439 FEPLYRGE SR+R I+QRII+RHGGE+ NHP+GGAML GW+P Sbjct: 386 FEPLYRGEASRSRSTGGSGLGLTITQRIIRRHGGEITVSNHPKGGAMLEGWLPA 439 >Q5WKN7.1 Q5WKN7_BACSK Sensor protein EC=2.7.13.3 Length = 439 Score = 552 bits (1422), Expect = e-155, Method: Compositional matrix adjust. Identities = 268/417 (64%), Positives = 326/417 (78%), Gaps = 4/417 (0%) Query: 26 VTSHYMETKTFSFTKSQPQNETLQRQLTEMIHLIETGSDKWMDPNWQNQLHKELRKAKMD 85 VT+H++ETKTF F S P +E LQR +TE IH IET +D W D NWQ QL +LRKA ++ Sbjct: 26 VTAHFIETKTFRF--STP-DENLQRHVTETIHTIETNADNWTDANWQCQLETQLRKANLE 82 Query: 86 VAILSEYG-QEIYRSNPERRGALSSTERFSIIEHGHLLGRVILYLPKSNTVQMISIFSGL 144 VAILS QE+YRSNPE SSTERFS+IE G LLG+V++Y+P S V IS G Sbjct: 83 VAILSAASNQEMYRSNPESSSWFSSTERFSLIEDGQLLGKVVIYVPSSRMVPTISAIVGF 142 Query: 145 LLAFFVVGVEMRRFLLKPLENMSVAARQIAAGEWDVQLPLSRITEITEVRDGFEVMVKGL 204 LLAF +VG+ +RRF L+PLE M + AR+IAAGE+D QLP+ RITEI +V GFEVM+KGL Sbjct: 143 LLAFIIVGIALRRFFLQPLERMGLVARKIAAGEFDGQLPIGRITEIADVGAGFEVMMKGL 202 Query: 205 QKSYRKQVELEEERRFVIAAVAHDLRTPLFALRGYLDGLEQGIAQSPEKITKYVAVCKEK 264 + S KQ+ LEEERRF+IAA+AHDLRTPLFALRGYLDGLEQGIA+SP+KITKYVAVCKEK Sbjct: 203 RTSQHKQMALEEERRFMIAAIAHDLRTPLFALRGYLDGLEQGIAKSPDKITKYVAVCKEK 262 Query: 265 SAQLDRLVEDLFTFTKMEYWETKLNNKAVDLKLILRKSIDSLSPLAWQKHISISNHAADD 324 S QLDRLVEDLFTFT MEY E + N + +DLK + +++ID L PLA QKHISIS ++ Sbjct: 263 SRQLDRLVEDLFTFTTMEYMEQQKNVRPIDLKDLFQQTIDGLRPLAQQKHISISTDFEEN 322 Query: 325 CIISGDTHLLERAMNNLLDNAVRHTPSNGEIVVQCYKDGNKVKFTIRDTGPGFSSEELQQ 384 C+I GD+HLLERA+NNL DNA+RHTPS+G IVV+CYK+ V F+++DTGPGFSSEEL++ Sbjct: 323 CMIRGDSHLLERALNNLFDNAIRHTPSSGNIVVRCYKEDANVTFSLKDTGPGFSSEELER 382 Query: 385 VFEPLYRGEESRNRXXXXXXXXXXISQRIIKRHGGELAAGNHPEGGAMLTGWIPVAN 441 VFEPL+RGE SRNR ISQRIIK+HGGELAA NH +GGA ++GW+P N Sbjct: 383 VFEPLFRGEVSRNRSTGGSGLGLTISQRIIKQHGGELAAKNHLDGGAFISGWLPGDN 439 >C4CR26.1 C4CR26_9CHLR Signal transduction histidine kinase, COG0642 Length = 477 Score = 312 bits (799), Expect = 5e-83, Method: Compositional matrix adjust. Identities = 169/407 (41%), Positives = 240/407 (58%), Gaps = 22/407 (5%) Query: 52 LTEMIHLIETGSDKWMDPNWQNQLHKELRKAKMDVAILSEYGQEIYRSNPERRGALSSTE 111 L+ I G+ +W DP WQ+ +L +D +L E G+E+YRS P+ Sbjct: 46 LSTATEQIGRGTTRWHDPAWQDATRSDLAAMGIDF-VLVEDGREVYRSTPDPLAGDGGQV 104 Query: 112 RFSIIEHGHLLG--RVILYL---------------PKSN--TVQMISIFSGLLLAFFVVG 152 R +E G R + Y+ P++ V ++ + S LLL +G Sbjct: 105 RERWVERVAYPGTPRRVAYIYSDSGVGWNGQDGGPPEARFLAVPIVGLIS-LLLTLAGIG 163 Query: 153 VEMRRFLLKPLENMSVAARQIAAGEWDVQLPLSRITEITEVRDGFEVMVKGLQKSYRKQV 212 + R +++PL S AARQ+AAG+ DV+LP SR+ E+ EV FE M L+ S R+Q Sbjct: 164 WFLGRTVVRPLAATSQAARQVAAGDLDVRLPSSRVREVAEVNAAFESMSAELRASLRQQA 223 Query: 213 ELEEERRFVIAAVAHDLRTPLFALRGYLDGLEQGIAQSPEKITKYVAVCKEKSAQLDRLV 272 E E ERR I AV HDLRTPLFALRGYL+GLE+G+ +PEK +Y+AV +EK+A L+RL+ Sbjct: 224 EFEHERRLFIGAVVHDLRTPLFALRGYLEGLEKGLDDTPEKRARYIAVAQEKAATLERLI 283 Query: 273 EDLFTFTKMEYWETKLNNKAVDLKLILRKSIDSLSPLAWQKHISIS-NHAADDCIISGDT 331 DLF FT++EY E N + +DL +L + ++ P A K + ++ + C + GDT Sbjct: 284 GDLFDFTRLEYLEQTPNPEPLDLGALLDRLVEGFRPQADTKGVQLTLTIPPEPCWVQGDT 343 Query: 332 HLLERAMNNLLDNAVRHTPSNGEIVVQCYKDGNKVKFTIRDTGPGFSSEELQQVFEPLYR 391 HLL RA++NLLDNA+R+TPS G++ V C + + V FTI DTGPG + +L +F PLYR Sbjct: 344 HLLTRALSNLLDNALRYTPSGGQVRVACRTEPSGVIFTIADTGPGIPAHDLPNLFAPLYR 403 Query: 392 GEESRNRXXXXXXXXXXISQRIIKRHGGELAAGNHPEGGAMLTGWIP 438 GE SRNR I++RI+ HGG+L+AGN GGA+ TG +P Sbjct: 404 GETSRNRRTGGAGLGLTIARRILLAHGGDLSAGNGQAGGAVFTGRLP 450 >Q67RL7.1 Q67RL7_SYMTH Sensor protein EC=2.7.13.3 Length = 459 Score = 180 bits (457), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 92/236 (38%), Positives = 141/236 (59%), Gaps = 3/236 (1%) Query: 157 RFLLKPLENMSVAARQIAAGEWDVQLPLSRITEITEVRDGFEVMVKGLQKSYRKQVELEE 216 R +L+PL + A R +A G+ D LP SR+ E+ + F M LQ + +Q L+E Sbjct: 174 RAVLRPLRALEAATRAVAEGDLDFALPRSRVQELDALGQAFTAMRDRLQAALERQAALQE 233 Query: 217 ERRFVIAAVAHDLRTPLFALRGYLDGLEQGIAQSPEKITKYVAVCKEKSAQLDRLVEDLF 276 ERR +IAA+ HDLRTPL ++R + +GL G+A+ P K Y V K+A+++RLVEDLF Sbjct: 234 ERRQLIAAIGHDLRTPLSSVRAFAEGLRDGLAREPAKAAHYADVILRKTAEVERLVEDLF 293 Query: 277 TFTKMEYWETKLNNKAVDLKLILRKSIDSLSPLAWQKHISISNHAADDCIISG-DTHLLE 335 F+++E ET+ + VDL L+ ++ + A QK + ++ D + +G D LL Sbjct: 294 QFSRLELPETRAALREVDLAAFLKATLGAFGAQAEQKGVVLAAEGPD--LTAGLDPALLG 351 Query: 336 RAMNNLLDNAVRHTPSNGEIVVQCYKDGNKVKFTIRDTGPGFSSEELQQVFEPLYR 391 RA++NL+ NA+RHTP G+I + + G +V + DTG G EEL +F P++R Sbjct: 352 RALDNLIANALRHTPPGGQIRLTWGRHGGEVCIAVADTGEGIPPEELPHLFTPMHR 407 >C2NP30.1 C2NP30_BACCE Putative uncharacterized protein Length = 484 Score = 158 bits (399), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 83/271 (30%), Positives = 153/271 (56%), Gaps = 2/271 (0%) Query: 155 MRRFLLKPLENMSVAARQIAAGEWDVQLPLSRITEITEVRDGFEVMVKGLQKSYRKQVEL 214 + R ++KP+ + A +I G D Q+P++ EI ++ GFE M K L++S Q + Sbjct: 192 VSRSVVKPIFVLKDATEKIKEGNLDFQIPVTSHDEIGQLNQGFEEMRKKLKESIEMQTQY 251 Query: 215 EEERRFVIAAVAHDLRTPLFALRGYLDGLEQGIAQSPEKITKYVAVCKEKSAQLDRLVED 274 EE R+ +I+ ++HDL+TP+ ++ GY++G++ G+A +PEK+ KY+ K+ +D L+++ Sbjct: 252 EENRKELISNISHDLKTPITSIIGYVEGIKDGVANTPEKMDKYLTTIHTKARHMDTLIDE 311 Query: 275 LFTFTKMEYWETKLNNKAVDLKLILRKSIDSLSPLAWQKHISISNHA-ADDCIISGDTHL 333 LF F+K++ + V+L + +++ I+ + ++ I ++ A ++ D Sbjct: 312 LFLFSKLDLNRVPFQFETVELNMFMQELIEEMQMDLSKEGIEVNLQLHASPLYVTADCEK 371 Query: 334 LERAMNNLLDNAVRHT-PSNGEIVVQCYKDGNKVKFTIRDTGPGFSSEELQQVFEPLYRG 392 + R ++NL+ N+V++ +I V D NKV T+ D G G S+ L +FE YR Sbjct: 372 INRVISNLIHNSVKYMDKEEKKITVTVSSDNNKVIVTVMDNGSGIESDTLPYIFERFYRA 431 Query: 393 EESRNRXXXXXXXXXXISQRIIKRHGGELAA 423 E+SRN I+++II+ HGG + A Sbjct: 432 EQSRNSSTGGSGLGLAIAKQIIEEHGGNIWA 462 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.134 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,371,643,093 Number of extensions: 93493630 Number of successful extensions: 334493 Number of sequences better than 1.0e-05: 23372 Number of HSP's gapped: 306811 Number of HSP's successfully gapped: 23429 Length of query: 443 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 304 Effective length of database: 1,751,175,118 Effective search space: 532357235872 Effective search space used: 532357235872 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)