BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0420.0003.p (250 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KKP8.1 B3KKP8_9BACI Protoheme IX farnesyltransferase 272 2e-71 B1DJ46.1 B1DJ46_9BACL Protoheme IX farnesyltransferase 210 7e-53 C4HYL6.1 C4HYL6_YERPE Protoheme IX farnesyltransferase 155 4e-36 C4HLV6.1 C4HLV6_YERPE Protoheme IX farnesyltransferase 155 4e-36 C4H979.1 C4H979_YERPE Protoheme IX farnesyltransferase 155 4e-36 >B3KKP8.1 B3KKP8_9BACI Protoheme IX farnesyltransferase Length = 312 Score = 272 bits (696), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 148/216 (68%), Positives = 169/216 (78%), Gaps = 5/216 (2%) Query: 1 VDNQLRYQXXXXXXXXXXXXP---KEGAGWRDFITVTKPGIIRSNLIAAFAGYWVASGWD 57 +DN LRYQ P + W+DFITVTKPGIIRSNLIAAFAG+W+AS WD Sbjct: 1 MDNHLRYQAPSESAALASAAPAPPDKAGTWKDFITVTKPGIIRSNLIAAFAGFWLASRWD 60 Query: 58 VQYGRLILTLLGTMLVMASACVFNNYFDRDLDMKMERTRERGLPTGRLKPQTVLIYAIGL 117 +Q+G +I+TLLGT+LVMAS+CVFNNYFDR+LDMKMERTR R LPTGRL P+ VL YA+ L Sbjct: 61 IQFGLMIMTLLGTVLVMASSCVFNNYFDRELDMKMERTRNRSLPTGRLTPKVVLWYAVIL 120 Query: 118 GIAGLAVLFAFCGVLAGIFGIVGMFVYVVVYTLWLKRTSTWSTSVGAISGAMPPVIGYVA 177 G+ GLAVLF F GVLAG+FG VGMFVYVVVYTLWLKR+STWSTSVGAISGAMPPVIGYVA Sbjct: 121 GVVGLAVLFLFSGVLAGLFGAVGMFVYVVVYTLWLKRSSTWSTSVGAISGAMPPVIGYVA 180 Query: 178 VTGAVDLGAWLLFAMLXXXXPAAF--LGARHPPQGR 211 VTG+VD+ A LLFA+L P F LG R + R Sbjct: 181 VTGSVDMAAVLLFALLFLWQPPHFWALGIRRVEEYR 216 >B1DJ46.1 B1DJ46_9BACL Protoheme IX farnesyltransferase Length = 284 Score = 210 bits (535), Expect = 7e-53, Method: Compositional matrix adjust. Identities = 103/186 (55%), Positives = 132/186 (70%), Gaps = 2/186 (1%) Query: 28 RDFITVTKPGIIRSNLIAAFAGYWVASGWDVQYGRLILTLLGTMLVMASACVFNNYFDRD 87 +D I +TKP ++R N+ AA G+WVAS WD+ + L+ ++G+ + + SACV NNY+DR+ Sbjct: 3 KDLIALTKPRLLRLNVFAAIGGFWVASKWDIDWLTLLWVVIGSAVTIGSACVINNYWDRE 62 Query: 88 LDMKMERTRERGLPTGRLKPQTVLIYAIGLGIAGLAVLFAFCGVLAGIFGIVGMFVYVVV 147 LD KMERT++R LPTGRL+P VL Y I LGI GLA+LF + G G +G FVY+ + Sbjct: 63 LDQKMERTKDRALPTGRLQPGFVLGYGIVLGIIGLAILFVLVNPVTGWLGFLGWFVYIFI 122 Query: 148 YTLWLKRTSTWSTSVGAISGAMPPVIGYVAVTGAVDLGAWLLFAMLXXXXPAAF--LGAR 205 YT+WLKRTSTWSTS+G ISGAMPPV+GY AVT VD+GAWLLFA L PA F L R Sbjct: 123 YTIWLKRTSTWSTSIGGISGAMPPVLGYCAVTNEVDMGAWLLFAFLFLWQPAHFWSLAIR 182 Query: 206 HPPQGR 211 + R Sbjct: 183 RVEEYR 188 >C4HYL6.1 C4HYL6_YERPE Protoheme IX farnesyltransferase Length = 296 Score = 155 bits (391), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 81/163 (49%), Positives = 109/163 (66%) Query: 28 RDFITVTKPGIIRSNLIAAFAGYWVASGWDVQYGRLILTLLGTMLVMASACVFNNYFDRD 87 + ++ VTKPGII NLI+ G+ +AS D+ Y + TLLG LV+AS CVFNNY DRD Sbjct: 4 KQYLQVTKPGIIFGNLISVIGGFLLASKGDIDYPLFLSTLLGVSLVVASGCVFNNYIDRD 63 Query: 88 LDMKMERTRERGLPTGRLKPQTVLIYAIGLGIAGLAVLFAFCGVLAGIFGIVGMFVYVVV 147 +D MERT+ R L G + P+ LIYA LGIAG+ +L+ LA + ++G +YV V Sbjct: 64 IDKIMERTKNRVLVKGLIDPKVSLIYASVLGIAGMLLLYVAANALAMMLAVIGFVIYVGV 123 Query: 148 YTLWLKRTSTWSTSVGAISGAMPPVIGYVAVTGAVDLGAWLLF 190 Y+L++KR S + T +G++SGA PPVIGY AVTG D GA +L Sbjct: 124 YSLYMKRKSVYGTLIGSLSGAAPPVIGYCAVTGQFDTGALILL 166 >C4HLV6.1 C4HLV6_YERPE Protoheme IX farnesyltransferase Length = 296 Score = 155 bits (391), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 81/163 (49%), Positives = 109/163 (66%) Query: 28 RDFITVTKPGIIRSNLIAAFAGYWVASGWDVQYGRLILTLLGTMLVMASACVFNNYFDRD 87 + ++ VTKPGII NLI+ G+ +AS D+ Y + TLLG LV+AS CVFNNY DRD Sbjct: 4 KQYLQVTKPGIIFGNLISVIGGFLLASKGDIDYPLFLSTLLGVSLVVASGCVFNNYIDRD 63 Query: 88 LDMKMERTRERGLPTGRLKPQTVLIYAIGLGIAGLAVLFAFCGVLAGIFGIVGMFVYVVV 147 +D MERT+ R L G + P+ LIYA LGIAG+ +L+ LA + ++G +YV V Sbjct: 64 IDKIMERTKNRVLVKGLIDPKVSLIYASVLGIAGMLLLYVAANALAMMLAVIGFVIYVGV 123 Query: 148 YTLWLKRTSTWSTSVGAISGAMPPVIGYVAVTGAVDLGAWLLF 190 Y+L++KR S + T +G++SGA PPVIGY AVTG D GA +L Sbjct: 124 YSLYMKRKSVYGTLIGSLSGAAPPVIGYCAVTGQFDTGALILL 166 >C4H979.1 C4H979_YERPE Protoheme IX farnesyltransferase Length = 296 Score = 155 bits (391), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 81/163 (49%), Positives = 109/163 (66%) Query: 28 RDFITVTKPGIIRSNLIAAFAGYWVASGWDVQYGRLILTLLGTMLVMASACVFNNYFDRD 87 + ++ VTKPGII NLI+ G+ +AS D+ Y + TLLG LV+AS CVFNNY DRD Sbjct: 4 KQYLQVTKPGIIFGNLISVIGGFLLASKGDIDYPLFLSTLLGVSLVVASGCVFNNYIDRD 63 Query: 88 LDMKMERTRERGLPTGRLKPQTVLIYAIGLGIAGLAVLFAFCGVLAGIFGIVGMFVYVVV 147 +D MERT+ R L G + P+ LIYA LGIAG+ +L+ LA + ++G +YV V Sbjct: 64 IDKIMERTKNRVLVKGLIDPKVSLIYASVLGIAGMLLLYVAANALAMMLAVIGFVIYVGV 123 Query: 148 YTLWLKRTSTWSTSVGAISGAMPPVIGYVAVTGAVDLGAWLLF 190 Y+L++KR S + T +G++SGA PPVIGY AVTG D GA +L Sbjct: 124 YSLYMKRKSVYGTLIGSLSGAAPPVIGYCAVTGQFDTGALILL 166 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.326 0.141 0.450 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,339,840,715 Number of extensions: 52216395 Number of successful extensions: 207455 Number of sequences better than 1.0e-05: 1439 Number of HSP's gapped: 206593 Number of HSP's successfully gapped: 1439 Length of query: 250 Length of database: 3,060,696,203 Length adjustment: 132 Effective length of query: 118 Effective length of database: 1,817,122,223 Effective search space: 214420422314 Effective search space used: 214420422314 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 129 (54.3 bits)