BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0419.0002.p (356 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KA30.1 B3KA30_9BACI Beta-lactamase domain protein 343 1e-92 B1DDV6.1 B1DDV6_9BACL Beta-lactamase domain protein 253 2e-65 A9B110.1 A9B110_HERA2 Beta-lactamase domain protein 199 4e-49 A5USF6.1 A5USF6_ROSS1 Beta-lactamase domain protein 199 4e-49 A7NR30.1 A7NR30_ROSCS Beta-lactamase domain protein 196 3e-48 >B3KA30.1 B3KA30_9BACI Beta-lactamase domain protein Length = 340 Score = 343 bits (880), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 175/308 (56%), Positives = 211/308 (68%), Gaps = 5/308 (1%) Query: 24 EGGIIQFSVPMAPPLRQVNSYILPDRNGQLTVIDPGPHTPEAEAAWEAVLQELDCSWSTI 83 E + Q + ++ PLR VNSY+L +G +TVIDPGP T +E W A +++L+ +S I Sbjct: 17 EHQLSQVKITLSNPLRWVNSYVLRGDDG-VTVIDPGPRTASSEREWLAAMEQLEMDFSDI 75 Query: 84 RDIVVTHHHPDHYGLAGWLQARSGGKVWMSERAHEEARLTWGAEGMLNEALPLFFLRYGM 143 +V+THHHPDHYGLAGW Q RSG KVWMSERAH EA L WGA+ ++ ALP FF ++GM Sbjct: 76 VSVVLTHHHPDHYGLAGWFQERSGAKVWMSERAHREAMLMWGADSSMDRALPAFFRQHGM 135 Query: 144 PEDWVQGIREHLESFLPQVTPQPEVAYINAAEPFIMGNRKWKPLVTGGHAPGHLSFYHGG 203 PE + ++EHL SF PQVTPQPE+++I PF MGNR W P+ T GHAPGHLSF+H Sbjct: 136 PETKLALLKEHLNSFFPQVTPQPEISFIGEDLPFRMGNRIWMPVQTAGHAPGHLSFFHAD 195 Query: 204 XXXGLILCGDAVLPQISPNVSLQPGSDPQPLRTFLEGLRELRSLRVTRAFPGHREPFTGF 263 G++LCGDAVLPQISPNVSL PGSD +PL FL GLR LR L V A+PGHR PFT F Sbjct: 196 --SGVLLCGDAVLPQISPNVSLVPGSDAEPLALFLAGLRRLRELHVRTAYPGHRHPFTHF 253 Query: 264 TERADSLLRHHEERLEQXX-XXXXXXXXXXXXVCEALFRSRVSSAHQMRFAMSEALAHLA 322 ER D+LL HHEERL VC ALF ++ HQ+RFAM EALAHLA Sbjct: 254 RERIDALLLHHEERLTTIAGMLSAAGRLTAYEVCTALFGDKL-GIHQLRFAMCEALAHLA 312 Query: 323 ELVRRERA 330 EL RR A Sbjct: 313 ELARRGEA 320 >B1DDV6.1 B1DDV6_9BACL Beta-lactamase domain protein Length = 328 Score = 253 bits (646), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 132/314 (42%), Positives = 178/314 (56%), Gaps = 4/314 (1%) Query: 22 TWEGGIIQFSVPMAPPLRQVNSYILPDRNGQLTVIDPGPHTPEAEAAWEAVLQELDCSWS 81 W+GG IQ +P+ L+ VNSY++P+ G TVIDPG HT +A AAWE V + Sbjct: 7 VWDGGWIQVKIPLPFSLKWVNSYLIPEDGGTYTVIDPGLHTDDALAAWEEVFLNHALTLE 66 Query: 82 TIRDIVVTHHHPDHYGLAGWLQARSGGKVWMSERAHEEARLTWGAEGMLNEALPLFFLRY 141 I IV+TH HPDHYGLAG+ Q R+G V++SER+H R WG E L F + Sbjct: 67 QINRIVLTHQHPDHYGLAGYFQERTGAPVYISERSHGYTRRLWGESSTYAEELRAHFAIH 126 Query: 142 GMPEDWVQGIREHLESFLPQVTPQPEVAYINAAEPFIMGNRKWKPLVTGGHAPGHLSFYH 201 GMP++ I+ +L+ F+ QV+PQPEV Y+ A +G +W+ + GHA G L FY Sbjct: 127 GMPDELTLDIKNNLDGFVRQVSPQPEVTYLKAGGTIRLGGTEWQMIDAPGHAFGQLCFYE 186 Query: 202 GGXXXGLILCGDAVLPQISPNVSLQPGSDPQPLRTFLEGLRELRSLRVTRAFPGHREPFT 261 ++CGD VLP+I+PN++ PG + PL FL L EL +V AFPGHREPF Sbjct: 187 PNKET--MICGDQVLPRITPNIAFNPGEEEDPLGCFLNSLDELSGYKVKLAFPGHREPFA 244 Query: 262 GFTERADSLLRHHEERLEQXXXXXXXXXXXXXXVCEALFRSRV-SSAHQMRFAMSEALAH 320 F R + HH+ RL + VCE LF + ++ H +RFAMSE +AH Sbjct: 245 DFANRIVEIKEHHKRRLTK-MRDMLREPSSAFEVCEHLFGGHLRTNPHNLRFAMSETIAH 303 Query: 321 LAELVRRERAEVTG 334 L L +R + TG Sbjct: 304 LHYLEKRGKVIRTG 317 >A9B110.1 A9B110_HERA2 Beta-lactamase domain protein Length = 324 Score = 199 bits (506), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 111/295 (37%), Positives = 157/295 (53%), Gaps = 7/295 (2%) Query: 32 VPMAPPLRQVNSYILPDRNGQLTVIDPGPHTPEAEAAWEAVLQELDCSWSTIRDIVVTHH 91 +P+ PL+ VN Y+L +G VID G +AE W+A ++L +WS I+ I+VTH+ Sbjct: 14 IPVPLPLKYVNCYLLKADHG-WVVIDTGMRYAQAEQTWQATFEQLGIAWSQIKQIIVTHY 72 Query: 92 HPDHYGLAGWLQARSGGKVWMSERAHEEARLTWGAEGMLNEA--LPLFFLRYGMPEDWVQ 149 HPDHYG+AGW+ RSG VWMS + + W + + + A L FF +GMP D + Sbjct: 73 HPDHYGMAGWMAERSGASVWMSPIEIQSVQRAW-YQPLPDAADHLADFFELHGMPNDLNR 131 Query: 150 GIREHLESFLPQVTPQPEVAYINAAEPFIMGNRKWKPLVTGGHAPGHLSFYHGGXXXGLI 209 I +H V P+P + ++ +P +G R W+ L GHA G L Y L+ Sbjct: 132 QIWQHTMDASQYVDPKPLLQTLDMTQPLQLGQRSWQLLHAPGHADGQLCLYDAADQ--LL 189 Query: 210 LCGDAVLPQISPNVSLQPGSDPQPLRTFLEGLRELRSLRVTRAFPGHREPFTGFTERADS 269 + D VL I+PN+SL P + PL +L L E +L V A GHR+P F ER Sbjct: 190 IVADHVLADITPNISLWPEAKRDPLADYLASLNEFAALDVRLALAGHRKPIMAFRERCHE 249 Query: 270 LLRHHEERLEQXXXXXXXXXXXXXXVCEALFRSRVSSAHQMRFAMSEALAHLAEL 324 + +HH++RL+ VCE F SAHQ+RFA++E LAHL L Sbjct: 250 IAQHHDQRLD-LMQQYASTGKTAFEVCEFAFGVTTLSAHQLRFAITETLAHLVYL 303 >A5USF6.1 A5USF6_ROSS1 Beta-lactamase domain protein Length = 321 Score = 199 bits (506), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 121/306 (39%), Positives = 161/306 (52%), Gaps = 5/306 (1%) Query: 27 IIQFSVPMAPPLRQVNSYILPDRNGQLTVIDPGPHTPEAEAAWEAVLQELDCSWSTIRDI 86 I Q +P+ PLR VN+Y++ D +G T+ID G + P AAW ++IR I Sbjct: 4 IHQVQLPLPFPLRIVNAYLMRDDDG-WTIIDAGLNYPPGRAAWREAFNRYGVDPASIRRI 62 Query: 87 VVTHHHPDHYGLAGWLQARSGGKVWMSERAHEEARLTWGAEGMLNEALPLFFLRYGMPED 146 V+TH HPDHYG+AGWLQ+ SG V +S AR W ++ +E FF +GMP D Sbjct: 63 VLTHAHPDHYGMAGWLQSLSGASVALSAGEAAFARAQWHSDSRAHEITATFFGAHGMPRD 122 Query: 147 WVQGIREHLESFLPQVTPQPEV-AYINAAEPFIMGNRKWKPLVTGGHAPGHLSFYHGGXX 205 + + E + + P P V ++ A EP +G R + P+ T GH+ HL FY Sbjct: 123 LMATVTEDIVNLRLMTHPTPVVLTHLPAGEPLTIGRRVFVPVATPGHSDDHLVFY--CAE 180 Query: 206 XGLILCGDAVLPQISPNVSLQPGSDPQPLRTFLEGLRELRSLRVTRAFPGHREPFTGFTE 265 L++CGDAVL +I+PNV L + PL FL L L L V A PGH P T F E Sbjct: 181 ERLLICGDAVLIKITPNVGLWGWTHGNPLAQFLASLDRLAELDVALALPGHGPPITRFHE 240 Query: 266 RADSLLRHHEERLEQXXXXXXXXXXXXXXVCEALFRSRVSSAHQMRFAMSEALAHLAELV 325 R + L HH ERL VC A+F + ++HQMRFAM+E LAHL L Sbjct: 241 RLEELRIHHAERL-AAMERAVGAGATAYDVCTAVFPLQELTSHQMRFAMAETLAHLEYLA 299 Query: 326 RRERAE 331 + R E Sbjct: 300 TQGRIE 305 >A7NR30.1 A7NR30_ROSCS Beta-lactamase domain protein Length = 321 Score = 196 bits (497), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 123/307 (40%), Positives = 158/307 (51%), Gaps = 5/307 (1%) Query: 26 GIIQFSVPMAPPLRQVNSYILPDRNGQLTVIDPGPHTPEAEAAWEAVLQELDCSWSTIRD 85 GI Q +P+ PLR VN+Y++ D G TVID G + +AAW I+ Sbjct: 3 GIHQVHLPLPFPLRIVNTYLIRDGEGW-TVIDTGLNYAPGQAAWHEAFARHGVDPRMIKR 61 Query: 86 IVVTHHHPDHYGLAGWLQARSGGKVWMSERAHEEARLTWGAEGMLNEALPLFFLRYGMPE 145 IV+TH HPDHYG+AGWLQA S V +S AR W A+ ++A FF +GMP Sbjct: 62 IVLTHAHPDHYGMAGWLQALSDAPVALSAGEAAFARAQWHADSHAHDATATFFGAHGMPP 121 Query: 146 DWVQGIREHLESFLPQVTPQPEVA-YINAAEPFIMGNRKWKPLVTGGHAPGHLSFYHGGX 204 D + + + + P P V Y+ EP ++G R + P+ T GH+ HL FY Sbjct: 122 DLMTTVADDITHLRMMTHPVPSVVTYLPVGEPLLIGERLFTPIATPGHSDDHLVFY--CA 179 Query: 205 XXGLILCGDAVLPQISPNVSLQPGSDPQPLRTFLEGLRELRSLRVTRAFPGHREPFTGFT 264 L++CGDAVL +I+PNV L S PL FL L L L V A PGH T F Sbjct: 180 EERLLICGDAVLIKITPNVGLWGWSRGNPLAQFLASLDRLAELDVALALPGHGPLITRFH 239 Query: 265 ERADSLLRHHEERLEQXXXXXXXXXXXXXXVCEALFRSRVSSAHQMRFAMSEALAHLAEL 324 ER D L HH ERLE VC A+F + ++HQMRFAM+E LAHL L Sbjct: 240 ERLDELRVHHVERLE-AMEHAIGAGATAYEVCTAVFPLQELTSHQMRFAMAETLAHLEYL 298 Query: 325 VRRERAE 331 + R E Sbjct: 299 ATQGRVE 305 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.135 0.427 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,202,179,962 Number of extensions: 92785328 Number of successful extensions: 212711 Number of sequences better than 1.0e-05: 343 Number of HSP's gapped: 211777 Number of HSP's successfully gapped: 346 Length of query: 356 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 219 Effective length of database: 1,770,017,148 Effective search space: 387633755412 Effective search space used: 387633755412 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 132 (55.5 bits)