BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0417.0020.p (378 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C0Z4Q1.1 C0Z4Q1_BREBN Probable NAD alcohol dehydrogenase 677 0.0 O06012.2 ADHB_BACSU Uncharacterized zinc-type alcohol dehydrogen... 670 0.0 A7Z1V5.1 A7Z1V5_BACA2 AdhB EC=1.1.1.1 662 0.0 Q2BDE1.1 Q2BDE1_9BACI Alcohol dehydrogenase 662 0.0 C1PAE6.1 C1PAE6_BACCO Alcohol dehydrogenase GroES domain protein 586 e-165 >C0Z4Q1.1 C0Z4Q1_BREBN Probable NAD alcohol dehydrogenase Length = 378 Score = 677 bits (1746), Expect = 0.0, Method: Compositional matrix adjust. Identities = 323/378 (85%), Positives = 347/378 (91%) Query: 1 MKAVTYQGIKNVVVKEVPDPKIEKPDDMIVKITSTAICGSDLHLIHGMIPNLQENYVIGH 60 MKAVTYQGIKNVVVKEVPDPK+EKPDDMIVK+TSTAICGSDLHL+HGMIPNLQE+Y+IGH Sbjct: 1 MKAVTYQGIKNVVVKEVPDPKLEKPDDMIVKLTSTAICGSDLHLVHGMIPNLQEDYIIGH 60 Query: 61 EPMGIVEEVGPGVTKVKKGDRVIIPFNIACGECFFCKNQLESQCDNSNEHGDMXXXXXXX 120 EPMGIVEEVGPGVTK+KKGDRVIIPF IACGECF+CKN LESQCDNSNE+GDM Sbjct: 61 EPMGIVEEVGPGVTKLKKGDRVIIPFTIACGECFYCKNHLESQCDNSNENGDMGGFFGYS 120 Query: 121 XXXXXXXXXQAEYLRVPFANFTHFKIPENCEQPDEKLSLIADAMTTAFWSVDNAGVKNGD 180 QAEYLRVPFANFTHFK+PENCE DEKL LIADAM TA+WSVDNAGVK+GD Sbjct: 121 GTTGGYPGGQAEYLRVPFANFTHFKLPENCEVEDEKLCLIADAMPTAYWSVDNAGVKDGD 180 Query: 181 TVIVLGCGPVGLLAQKFCWLKGAKRVIAVDYVDYRLQHAKRTNNVEIVNFKQDKNIGNNL 240 TVIVLGCGPVGLL QKFCWLKGAKRVIAVDY++YRLQHAKRTNNVEIVNF+Q +NIGN L Sbjct: 181 TVIVLGCGPVGLLVQKFCWLKGAKRVIAVDYIEYRLQHAKRTNNVEIVNFEQKENIGNYL 240 Query: 241 KEMTKGGADVVIDAVGMDGKMSDLEFLASGMKLQGGTMSAFIIASQAVRKGGTIQVTGVY 300 KE+TKGGADVVIDAVGMDGKMSDLEFLASG+KLQGG M A +IASQAVRKGGTIQ+TGVY Sbjct: 241 KEITKGGADVVIDAVGMDGKMSDLEFLASGLKLQGGAMGAIVIASQAVRKGGTIQITGVY 300 Query: 301 GGRYNGFPLGDIMQRNVNIRSGQAPVIHYMPYMYELVTSGKVDPGDIVTHVIPLSEAKRG 360 GGRYN FPLGDIMQRNVNIRSGQAPVIHYMPYMYEL+T+GKVDPGDI+THVIPL EAKRG Sbjct: 301 GGRYNAFPLGDIMQRNVNIRSGQAPVIHYMPYMYELITTGKVDPGDIITHVIPLGEAKRG 360 Query: 361 YEVFDTKMDDCIKVILKP 378 YEVFDTK D+CIKV+LKP Sbjct: 361 YEVFDTKTDNCIKVVLKP 378 >O06012.2 ADHB_BACSU Uncharacterized zinc-type alcohol dehydrogenase-like protein adhB EC=1.-.-.- Length = 378 Score = 670 bits (1729), Expect = 0.0, Method: Compositional matrix adjust. Identities = 317/378 (83%), Positives = 347/378 (91%) Query: 1 MKAVTYQGIKNVVVKEVPDPKIEKPDDMIVKITSTAICGSDLHLIHGMIPNLQENYVIGH 60 MKAVTYQGIKNVVVK+VPDPKIEK DDMI+K+TSTAICGSDLHLIHG IPN+QE+YVIGH Sbjct: 1 MKAVTYQGIKNVVVKDVPDPKIEKSDDMIIKVTSTAICGSDLHLIHGFIPNMQEDYVIGH 60 Query: 61 EPMGIVEEVGPGVTKVKKGDRVIIPFNIACGECFFCKNQLESQCDNSNEHGDMXXXXXXX 120 EPMGIVEEVG GVTK+KKGDRVIIPFNIACGECFFCKNQLESQCD SN++G+M Sbjct: 61 EPMGIVEEVGSGVTKLKKGDRVIIPFNIACGECFFCKNQLESQCDQSNDNGEMGAYFGYS 120 Query: 121 XXXXXXXXXQAEYLRVPFANFTHFKIPENCEQPDEKLSLIADAMTTAFWSVDNAGVKNGD 180 QAEYLRVPFANFTHFKIPE+CE+PDEKLS+IADAMTT FWSVDNAGVK GD Sbjct: 121 GQTGGYPGGQAEYLRVPFANFTHFKIPESCEEPDEKLSVIADAMTTGFWSVDNAGVKKGD 180 Query: 181 TVIVLGCGPVGLLAQKFCWLKGAKRVIAVDYVDYRLQHAKRTNNVEIVNFKQDKNIGNNL 240 TVIVLGCGPVGL AQKFCWLKGAKRVIAVDYV+YRLQHAKRTN VEIVNF+ +N GN L Sbjct: 181 TVIVLGCGPVGLFAQKFCWLKGAKRVIAVDYVNYRLQHAKRTNKVEIVNFEDHENTGNYL 240 Query: 241 KEMTKGGADVVIDAVGMDGKMSDLEFLASGMKLQGGTMSAFIIASQAVRKGGTIQVTGVY 300 KE+TKGGADVVIDAVGMDGKMSDLEFLASG+KL GGTMSA +IASQAVRKGGTIQ+TGVY Sbjct: 241 KEITKGGADVVIDAVGMDGKMSDLEFLASGLKLHGGTMSALVIASQAVRKGGTIQITGVY 300 Query: 301 GGRYNGFPLGDIMQRNVNIRSGQAPVIHYMPYMYELVTSGKVDPGDIVTHVIPLSEAKRG 360 GGRYNGFPLGDIMQRNVNIRSGQAPVIHYMPYM+ELV++GK+DPGD+V+HV+PLSEAK G Sbjct: 301 GGRYNGFPLGDIMQRNVNIRSGQAPVIHYMPYMFELVSTGKIDPGDVVSHVLPLSEAKHG 360 Query: 361 YEVFDTKMDDCIKVILKP 378 Y++FD+KMDDCIKV+LKP Sbjct: 361 YDIFDSKMDDCIKVVLKP 378 >A7Z1V5.1 A7Z1V5_BACA2 AdhB EC=1.1.1.1 Length = 378 Score = 662 bits (1709), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/378 (83%), Positives = 343/378 (90%) Query: 1 MKAVTYQGIKNVVVKEVPDPKIEKPDDMIVKITSTAICGSDLHLIHGMIPNLQENYVIGH 60 MKAVTYQG+KNVVVK+VPDPKIEK DDMI+K+TSTAICGSDLHLIHG+IPNLQE+Y+IGH Sbjct: 1 MKAVTYQGVKNVVVKDVPDPKIEKHDDMIIKVTSTAICGSDLHLIHGLIPNLQEDYIIGH 60 Query: 61 EPMGIVEEVGPGVTKVKKGDRVIIPFNIACGECFFCKNQLESQCDNSNEHGDMXXXXXXX 120 EPMGIVEE GPGVTKVKKGDRVIIPFNIACGEC +CKN LESQCD SNE+GD+ Sbjct: 61 EPMGIVEETGPGVTKVKKGDRVIIPFNIACGECVYCKNHLESQCDQSNENGDIGAYFGYS 120 Query: 121 XXXXXXXXXQAEYLRVPFANFTHFKIPENCEQPDEKLSLIADAMTTAFWSVDNAGVKNGD 180 QAEYLRVPFANFTHFK+PE CE+PDEKLS+IADAMTT FWSVDNAGVK GD Sbjct: 121 GNAGGYPGGQAEYLRVPFANFTHFKVPETCEEPDEKLSVIADAMTTGFWSVDNAGVKEGD 180 Query: 181 TVIVLGCGPVGLLAQKFCWLKGAKRVIAVDYVDYRLQHAKRTNNVEIVNFKQDKNIGNNL 240 TVIVLGCGPVGL AQKFCWLKGAKRVIAVDYV YRLQHAKRTN VEIVNF+ +N G+ L Sbjct: 181 TVIVLGCGPVGLFAQKFCWLKGAKRVIAVDYVYYRLQHAKRTNKVEIVNFEDHENTGSYL 240 Query: 241 KEMTKGGADVVIDAVGMDGKMSDLEFLASGMKLQGGTMSAFIIASQAVRKGGTIQVTGVY 300 KE+TKGGADVVIDAVGMDGKM+DLEFLASG+KLQGG MSA +IASQAVRKGGTIQ+TGVY Sbjct: 241 KEITKGGADVVIDAVGMDGKMTDLEFLASGLKLQGGAMSALVIASQAVRKGGTIQITGVY 300 Query: 301 GGRYNGFPLGDIMQRNVNIRSGQAPVIHYMPYMYELVTSGKVDPGDIVTHVIPLSEAKRG 360 GGRYNGFPLGDIMQRNVNIRSGQAPVIHYMPYM+ELV++GK+DPGD+V+HVIPLSEAK G Sbjct: 301 GGRYNGFPLGDIMQRNVNIRSGQAPVIHYMPYMFELVSTGKIDPGDVVSHVIPLSEAKHG 360 Query: 361 YEVFDTKMDDCIKVILKP 378 YE+FDTK DDCIKV+LKP Sbjct: 361 YEMFDTKTDDCIKVVLKP 378 >Q2BDE1.1 Q2BDE1_9BACI Alcohol dehydrogenase Length = 378 Score = 662 bits (1707), Expect = 0.0, Method: Compositional matrix adjust. Identities = 311/378 (82%), Positives = 346/378 (91%) Query: 1 MKAVTYQGIKNVVVKEVPDPKIEKPDDMIVKITSTAICGSDLHLIHGMIPNLQENYVIGH 60 MKAVTYQGIKNV VKEVPDP+IEKPDDMI+K+TSTAICGSDLHLIHG IPN+QE+YVIGH Sbjct: 1 MKAVTYQGIKNVEVKEVPDPRIEKPDDMIIKVTSTAICGSDLHLIHGFIPNMQEDYVIGH 60 Query: 61 EPMGIVEEVGPGVTKVKKGDRVIIPFNIACGECFFCKNQLESQCDNSNEHGDMXXXXXXX 120 EPMGIVEEVGP VTKVKKGDRVIIPFNIACGEC +CKNQLESQCDN+N++GDM Sbjct: 61 EPMGIVEEVGPEVTKVKKGDRVIIPFNIACGECIYCKNQLESQCDNTNDNGDMGAYFGYS 120 Query: 121 XXXXXXXXXQAEYLRVPFANFTHFKIPENCEQPDEKLSLIADAMTTAFWSVDNAGVKNGD 180 QAEYLRVPFANFTHFKIPE+CE+PDEKLS+IADAM+T FWSVDNAGVK+GD Sbjct: 121 GNTGGYPGGQAEYLRVPFANFTHFKIPESCEEPDEKLSVIADAMSTGFWSVDNAGVKSGD 180 Query: 181 TVIVLGCGPVGLLAQKFCWLKGAKRVIAVDYVDYRLQHAKRTNNVEIVNFKQDKNIGNNL 240 TVIVLGCGPVGL AQKF W+KGAKRVIAVDYVDYRLQHAKRTN VEI+NF+Q +N+G++L Sbjct: 181 TVIVLGCGPVGLFAQKFAWMKGAKRVIAVDYVDYRLQHAKRTNKVEIINFEQYENVGSHL 240 Query: 241 KEMTKGGADVVIDAVGMDGKMSDLEFLASGMKLQGGTMSAFIIASQAVRKGGTIQVTGVY 300 KE+T GGADVVIDAVGMDGKM+D+EFLASG+KLQGG MSA IIASQAVRK GTIQ+TGVY Sbjct: 241 KEITHGGADVVIDAVGMDGKMTDMEFLASGLKLQGGAMSALIIASQAVRKAGTIQITGVY 300 Query: 301 GGRYNGFPLGDIMQRNVNIRSGQAPVIHYMPYMYELVTSGKVDPGDIVTHVIPLSEAKRG 360 GGRYNGFPLGDIMQRNVNIRSGQAP+IH MPYMYELV +GK+DPGD+V+HV+PLSEAK G Sbjct: 301 GGRYNGFPLGDIMQRNVNIRSGQAPMIHLMPYMYELVATGKIDPGDVVSHVLPLSEAKHG 360 Query: 361 YEVFDTKMDDCIKVILKP 378 YE+FDTKMD+CIKV+LKP Sbjct: 361 YEIFDTKMDNCIKVVLKP 378 >C1PAE6.1 C1PAE6_BACCO Alcohol dehydrogenase GroES domain protein Length = 378 Score = 586 bits (1511), Expect = e-165, Method: Compositional matrix adjust. Identities = 277/378 (73%), Positives = 322/378 (85%) Query: 1 MKAVTYQGIKNVVVKEVPDPKIEKPDDMIVKITSTAICGSDLHLIHGMIPNLQENYVIGH 60 MKAVT+QGIK+V VK+VP+PKIEK DD+IVKITS+AICGSDLHLIHGMIPN E+Y+IGH Sbjct: 1 MKAVTFQGIKDVRVKDVPEPKIEKKDDIIVKITSSAICGSDLHLIHGMIPNFPEDYIIGH 60 Query: 61 EPMGIVEEVGPGVTKVKKGDRVIIPFNIACGECFFCKNQLESQCDNSNEHGDMXXXXXXX 120 EP+GIVEE GP VTKVKKGDRVIIPF +ACGEC++C + LESQCDN+N +G+M Sbjct: 61 EPLGIVEETGPDVTKVKKGDRVIIPFTVACGECWYCTHHLESQCDNANANGEMGGYFGYS 120 Query: 121 XXXXXXXXXQAEYLRVPFANFTHFKIPENCEQPDEKLSLIADAMTTAFWSVDNAGVKNGD 180 QAEYLRVP+ANFT FKIPEN E DE+L L++DA +TAFWSVDNAGVK+GD Sbjct: 121 HLTGGYPGGQAEYLRVPYANFTPFKIPENSEVKDEELVLLSDAASTAFWSVDNAGVKDGD 180 Query: 181 TVIVLGCGPVGLLAQKFCWLKGAKRVIAVDYVDYRLQHAKRTNNVEIVNFKQDKNIGNNL 240 TV+VLGCGPVGLLAQKF WLKGAKRVIAVDY+DYRLQHAK+ N VE VNF+Q N G L Sbjct: 181 TVVVLGCGPVGLLAQKFAWLKGAKRVIAVDYLDYRLQHAKKYNKVETVNFEQHDNTGEYL 240 Query: 241 KEMTKGGADVVIDAVGMDGKMSDLEFLASGMKLQGGTMSAFIIASQAVRKGGTIQVTGVY 300 KE+TKGGADVVIDAVGMDGKM+ +E+L SG+KLQGG MSA +IASQAVRKGGTIQVTGVY Sbjct: 241 KELTKGGADVVIDAVGMDGKMTPMEYLTSGLKLQGGAMSALVIASQAVRKGGTIQVTGVY 300 Query: 301 GGRYNGFPLGDIMQRNVNIRSGQAPVIHYMPYMYELVTSGKVDPGDIVTHVIPLSEAKRG 360 G RYN FPLGDI QRNV++R+GQAPVIHYMP++Y+LV KV DIVTHV+PL +A++G Sbjct: 301 GDRYNAFPLGDIFQRNVSLRTGQAPVIHYMPFLYDLVAQEKVTLSDIVTHVLPLDQAEKG 360 Query: 361 YEVFDTKMDDCIKVILKP 378 YEVFDT+ D+CIKV+LKP Sbjct: 361 YEVFDTRTDNCIKVVLKP 378 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.139 0.415 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,267,566,432 Number of extensions: 95305600 Number of successful extensions: 257043 Number of sequences better than 1.0e-05: 7361 Number of HSP's gapped: 245496 Number of HSP's successfully gapped: 8171 Length of query: 378 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 241 Effective length of database: 1,770,017,148 Effective search space: 426574132668 Effective search space used: 426574132668 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 132 (55.5 bits)