BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0417.0010.p (563 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A9QDR5.1 A9QDR5_9BACL YesM 568 e-160 Q9KB25.1 Q9KB25_BACHD BH2110 protein 443 e-122 B3K843.1 B3K843_9BACI Histidine kinase internal region 438 e-121 B9MQL3.1 B9MQL3_ANATD Putative sensor with HAMP domain 272 6e-71 A4XMX5.1 A4XMX5_CALS8 Integral membrane sensor signal transducti... 270 3e-70 >A9QDR5.1 A9QDR5_9BACL YesM Length = 572 Score = 568 bits (1463), Expect = e-160, Method: Compositional matrix adjust. Identities = 284/541 (52%), Positives = 379/541 (70%), Gaps = 10/541 (1%) Query: 21 SVFIPIVLTNVVFYNVTTSNLRNQKIRDADMALDNLKNELRVTIDQGVGLAYSLYGDSIF 80 VFIPIVLTN+VFYNVTT+N++NQK DAD+AL+ L+ ELR ID+ G++Y Y D + Sbjct: 22 CVFIPIVLTNIVFYNVTTNNIKNQKSHDADIALEKLQGELRAVIDEAAGISYLYYIDPML 81 Query: 81 NKTITRKFTSEKDYVETFNSYLRGAL--ADQNVQGVRWYQVYTDNPTVLASGYIDRLTDK 138 N+ + +K+ S+ +YVE FN+ +R ++Q + +YTDNPTVL+SG I L++ Sbjct: 82 NQLLDKKYDSQIEYVEAFNN-IRSVFNKSEQAYKTTSATVIYTDNPTVLSSGPIMPLSET 140 Query: 139 LRDTGWYTQSKASSSRYPTFIYSEQKFSLIQKLNNYHTSGIEQLVKIDLNMERIHQIFFG 198 ++ WY ++ YP FI FSL+Q+LN +G L+KIDLNM + Q+F Sbjct: 141 EKEADWYRAFMKTNVSYPLFIQDGDTFSLVQRLNYVKGNGYNNLIKIDLNMATVKQLFAL 200 Query: 199 SAFNGMVYLVDPQGRVQYGNDTA--KLPEGVPFKEISYPKNFLAFKNVYSGINYLEGWTL 256 S F G +Y ++P+G V Y ND++ + + +P PKN L+F VY+ NYL W+L Sbjct: 201 SGFEGSIYFLNPEGAVLYSNDSSVDRHSQTLPM-----PKNSLSFDKVYTNNNYLNDWSL 255 Query: 257 EGVIDEENVLKEVRKSRSFVIWLACINFVLPSIIIAAMSRSIHVRLVRILKHMKKVKAQN 316 GVI+E + L +VRKS SFVI+LA INFVLPS+IIAA+SRSI+ RLV+I+KHMKKVK Q+ Sbjct: 256 HGVINEGSFLHDVRKSGSFVIFLALINFVLPSLIIAALSRSINKRLVKIVKHMKKVKNQH 315 Query: 317 FQTIPHEEARDEIGQLTIEFNRMTETVNSLINEVYLADIQKKNLELKXXXXXXXXXXSQI 376 F+TIP ++ARDEIGQLT EFNRMTE +++LI +VY ADIQKK+LE++ SQI Sbjct: 316 FETIPLDDARDEIGQLTGEFNRMTERIDNLITDVYQADIQKKDLEIRQRQAQLHALHSQI 375 Query: 377 NPHFLFNSLESVRMRSLIKGEKETAKIIQHMAKMFRKSVSWSHNYVTVREELELIESFLT 436 NPHFLFNSLE++RMRSL+KGE ETAK I +MAK+FRKS+SW ++V++REE+EL E FL Sbjct: 376 NPHFLFNSLETIRMRSLMKGETETAKTIHYMAKIFRKSISWKRSWVSIREEIELTECFLE 435 Query: 437 IQQYRFGDKLEYSIVADPAALEHRIPKMVLLPFVENASIHGIESSPDKGIIVISVAVQRD 496 IQ+YRFGDKL+Y I + + IPKM LPFVENASIHGIESSP G+I I + + + Sbjct: 436 IQKYRFGDKLQYQITVEDTVYDQMIPKMTFLPFVENASIHGIESSPGIGLIQIHIGIAGN 495 Query: 497 RLIFRLEDNGIGMSPXXXXXXXXXXXXNDDIGERVGMKNAYYRLKLCFQDRFMFAMDARE 556 +L+FRL DNGIGMS +D IG+ VGMKN Y RLKLC++D F F + + E Sbjct: 496 KLMFRLSDNGIGMSQAKLSELLNYLRLDDSIGDNVGMKNVYTRLKLCYKDSFEFDIASEE 555 Query: 557 G 557 G Sbjct: 556 G 556 >Q9KB25.1 Q9KB25_BACHD BH2110 protein Length = 585 Score = 443 bits (1140), Expect = e-122, Method: Compositional matrix adjust. Identities = 230/550 (41%), Positives = 353/550 (64%), Gaps = 19/550 (3%) Query: 21 SVFIPIVLTNVVFYNVTTSNLRNQKIRDADMALDNLKNELRVTIDQGVGLAYSLYGDSIF 80 VF+PI+LTN++FYNVT +N++ QK+ D ++ +D + NE +DQ +G++ Y ++ Sbjct: 24 CVFLPILLTNIIFYNVTANNIKAQKMDDIELVVDQITNEFNNAVDQAIGISSGFYTNTRI 83 Query: 81 NKTITRKFTSEKDYVETFNSYLRG----ALADQNVQGVRWYQVYTDNPTVLASGYIDRLT 136 ++ + DY+E ++ YLR + ++Q + +Y TDNP+ + +G I LT Sbjct: 84 YDFFETEYETAIDYIEAYDFYLREYSRFSPLYYSIQSISFY---TDNPSFIYAGGIRPLT 140 Query: 137 DKLRDTGWYTQSKASSSRYPTFIYSEQK-----FSLIQKLNNYHTSGI--EQLVKIDLNM 189 + ++ WY + + +P I + FS+I++L+ YH + +++V+IDLN Sbjct: 141 EHTKEEKWYRL--LTEANHPIIIRTNPATDSGLFSVIRELD-YHKNKYNHKKIVRIDLNP 197 Query: 190 ERIHQIFFGSAFNGMVYLVDPQGRVQYGNDTAK--LPEGVPFKEISYPKNFLAFKNVYSG 247 I QIF +AF G VYL++ + +++ ++ E + F + +P++ + K Sbjct: 198 LTIKQIFNNAAFTGEVYLLNGERNIEFSSNEEVNWRTEQLHFDALEFPEDTIFTKERMLS 257 Query: 248 INYLEGWTLEGVIDEENVLKEVRKSRSFVIWLACINFVLPSIIIAAMSRSIHVRLVRILK 307 NYLEGW + G I E +L+E+ KSR F++ LA IN + P+++I +S+SIH RL+R+LK Sbjct: 258 QNYLEGWRVAGTISENEILEELYKSREFIVILASINLLFPTLLIVLISKSIHSRLLRVLK 317 Query: 308 HMKKVKAQNFQTIPHEEARDEIGQLTIEFNRMTETVNSLINEVYLADIQKKNLELKXXXX 367 HMK++K Q F I +DEIG+LT EFN+M++T+N LINEVY ++I+KK+L+L+ Sbjct: 318 HMKRMKKQKFDIINFPGDKDEIGELTNEFNKMSQTINRLINEVYASNIEKKDLQLREKQA 377 Query: 368 XXXXXXSQINPHFLFNSLESVRMRSLIKGEKETAKIIQHMAKMFRKSVSWSHNYVTVREE 427 SQINPHFLFN+LE++RMRS+IKGEKETAKIIQ+MAK+FR S++W ++VTVR+E Sbjct: 378 QLSALQSQINPHFLFNALETIRMRSMIKGEKETAKIIQNMAKIFRNSLTWGKDWVTVRDE 437 Query: 428 LELIESFLTIQQYRFGDKLEYSIVADPAALEHRIPKMVLLPFVENASIHGIESSPDKGII 487 L LI FL IQ+YRFGDK+EY + D A ++ IP MV LPFVENASIHGIES +KGII Sbjct: 438 LCLIICFLEIQKYRFGDKMEYELDIDEEAYDYIIPNMVFLPFVENASIHGIESVKEKGII 497 Query: 488 VISVAVQRDRLIFRLEDNGIGMSPXXXXXXXXXXXXNDDIGERVGMKNAYYRLKLCFQDR 547 I V +++ + DNG GM +++GE VG+KN YYRLKL +++ Sbjct: 498 QIRVEKNDGEIVYEISDNGAGMDEEKLASLIETLKNEENMGENVGIKNVYYRLKLHYKNH 557 Query: 548 FMFAMDAREG 557 F F++++R G Sbjct: 558 FDFSINSRPG 567 >B3K843.1 B3K843_9BACI Histidine kinase internal region Length = 580 Score = 438 bits (1127), Expect = e-121, Method: Compositional matrix adjust. Identities = 236/548 (43%), Positives = 339/548 (61%), Gaps = 12/548 (2%) Query: 21 SVFIPIVLTNVVFYNVTTSNLRNQKIRDADMALDNLKNELRVTIDQGVGLAYSLYGDSIF 80 +VF+PI++TN++FYNVT+ ++R Q+I+D +AL+ +KNE R ++ + ++ Y D Sbjct: 21 AVFLPILITNLIFYNVTSGSVREQRIQDITVALEQMKNEFRREVEDALEISSVFYTDVQL 80 Query: 81 NKTITRKFTSEKDYVETFNSYLRGALADQNV--QGVRWYQVYTDNPTVLASGYIDRLTDK 138 N+ + + DY+E +++YLR L + V VY DNPT+L SG I+ + + Sbjct: 81 NEIVETVYDHPADYIEAYDTYLRRILNSGSAVYNSVSEIAVYVDNPTLLYSGGINYIDGQ 140 Query: 139 LRDTGWYTQSKASSSRYPTFIYSEQ-----KFSLIQKLNNYHTSGIE-QLVKIDLNMERI 192 +++ WY + P + + + FS+I+ +N + + + +KID+ M I Sbjct: 141 VKEEAWYKAIAGKNVTQPIVMRTGKNGQLDSFSIIRSMNYFSSQDDHTKYLKIDMRMPSI 200 Query: 193 HQIFFGSAFNGMVYLVDPQGRVQYGNDT-AKLPEG-VPFKEISYPKNFLAFKNVYSGINY 250 QI G VYL+ G ++Y D + +G VP+ I++ FL F N Sbjct: 201 RQIMSNLNVQGKVYLLSGAGNIEYTTDPKVDVTQGAVPYSSIAHGDRFLEFHTDTFTTNN 260 Query: 251 LEGWTLEGVIDEENVLKEVRKSRSFVIWLACINFVLPSIIIAAMSRSIHVRLVRILKHMK 310 L WT+ V E+ VL++V +S FVI L C+NF+LPS++I +SRS++VRLVRILKHM+ Sbjct: 261 LNTWTIMAVTPEDVVLRDVHQSLRFVIVLTCLNFLLPSLVIVWISRSLNVRLVRILKHMR 320 Query: 311 KVKAQNFQTIPHEEARDEIGQLTIEFNRMTETVNSLINEVYLADIQKKNLELKXXXXXXX 370 KVK QN+ TI EARDEIGQLT EFNRMT + SLIN+VY+ADIQKKNLEL+ Sbjct: 321 KVKNQNYDTIQEAEARDEIGQLTGEFNRMTLQLKSLINDVYVADIQKKNLELQRRHAQLN 380 Query: 371 XXXSQINPHFLFNSLESVRMRSLIKGEKETAKIIQHMAKMFRKSVSWSHNYVTVREELEL 430 SQINPHFLFN+LE++RMRSL+K E ETA+II +MAK+FR S+ W + VT++EE+E Sbjct: 381 ALQSQINPHFLFNALETIRMRSLMKDEDETARIIHNMAKIFRNSLVWKKDMVTLKEEVEF 440 Query: 431 IESFLTIQQYRFGDKLEYSIVADPAALEH-RIPKMVLLPFVENASIHGIESSPDKGIIVI 489 I FL IQ+YRFGDK++YS+ A PA H +IPKM ++ FVENASIHGIE G I + Sbjct: 441 IHCFLEIQRYRFGDKIDYSVHA-PAEEGHLQIPKMAIVTFVENASIHGIEPLKHGGRIEV 499 Query: 490 SVAVQRDRLIFRLEDNGIGMSPXXXXXXXXXXXXNDDIGERVGMKNAYYRLKLCFQDRFM 549 V + L ++DNG GM D++GER+G++N YRLKL + RF Sbjct: 500 RVVREGQSLFCTIQDNGAGMPAEKVERIYRYLETEDEMGERIGIQNVIYRLKLYYGSRFR 559 Query: 550 FAMDAREG 557 F +D+ G Sbjct: 560 FEIDSSPG 567 >B9MQL3.1 B9MQL3_ANATD Putative sensor with HAMP domain Length = 610 Score = 272 bits (696), Expect = 6e-71, Method: Compositional matrix adjust. Identities = 181/556 (32%), Positives = 285/556 (51%), Gaps = 26/556 (4%) Query: 21 SVFIPIVLTNVVFYNVTTSNLRNQKIRDADMALDNLKNELRVTIDQGVGLAYSLYGDSIF 80 V IP ++++ +F NL+ QKI A + L ++ ID+ + + +LY D + Sbjct: 38 CVLIPTLVSHFIFTIFIIKNLQQQKITQIKSAFNILNTNIKKVIDEAILYSNTLYTDDLL 97 Query: 81 NKTITRKFTSEKDYVETFNSYLRGAL-ADQNV-QGVRWYQVYTDNPTVLAS-GYIDRLTD 137 N + + D+ + YLR + +NV + +YT+NPT+L S GY Sbjct: 98 NDMLDINYHGMDDFYSNYVQYLRNRIYQGRNVYSNIARVTIYTNNPTILNSDGYRKLNIQ 157 Query: 138 KLRDTGWYTQ---SKASSSRYPTF---IYSEQKF-SLIQKLNNY--------HTSGIEQL 182 ++++ WY + + PT + E+ + SLI+ LN Y + S ++ Sbjct: 158 EVKE--WYDKVINNLQGIVIIPTSDDGVNGEEGYVSLIRNLNQYEQRSTSTGNNSKYTKI 215 Query: 183 VKIDLNMERIHQIFFGSAFNGMVYLVDPQGRVQYGNDTAKLPEGVPFKEIS----YPKNF 238 KID+ + F G +YL+D R+ + L PF + PK Sbjct: 216 AKIDIYLSSFFNSINFEVFGGEIYLIDSSNRIIAAHTYNNLIFTKPFVKFETSKFVPKGS 275 Query: 239 LAFKNVYSGINYLEGWTLEGVIDEENVLKEVRKSRSFVIWLACINFVLPSIIIAAMSRSI 298 F N IN L GW L GV ++ E+ ++ F++ ++ ++ + + +I ++ SI Sbjct: 276 YVFVNNLD-INLLNGWKLVGVFSRSYMMGEIYRAIEFILLISLLSLIFATFLIRLITSSI 334 Query: 299 HVRLVRILKHMKKVKAQNFQTIPHEEARDEIGQLTIEFNRMTETVNSLINEVYLADIQKK 358 RL + +HM+KVK Q F+ + E DEIG L EFN MT + LI + L++IQKK Sbjct: 335 SNRLELLERHMRKVKKQRFEILTCREGNDEIGNLIREFNNMTIRLKELIEKEMLSEIQKK 394 Query: 359 NLELKXXXXXXXXXXSQINPHFLFNSLESVRMRSLIKGEKETAKIIQHMAKMFRKSVSWS 418 LE++ SQINPHFLFN+L+S+RMRS++K E ETA+II+++ + R+ + W Sbjct: 395 TLEVEKKQAEINALQSQINPHFLFNTLDSIRMRSVLKNELETAEIIKYLTRTLRRLIYWG 454 Query: 419 HNYVTVREELELIESFLTIQQYRFGDKLEYSIVADPAALEHRIPKMVLLPFVENASIHGI 478 ++ TV+EE+ +E FL IQQYRFG+KL Y I + A IPKM + P VENA IHGI Sbjct: 455 NDITTVQEEINFVEDFLKIQQYRFGEKLTYEIFVEEDAKNCLIPKMTIQPLVENACIHGI 514 Query: 479 ESSPDKGIIVISVAVQRDRLIFRLEDNGIGMSPXXXXXXXXXXXXNDDIGERVGMKNAYY 538 E D G +++ V + LI + DNGIGM+ N + +G+KN Y Sbjct: 515 EEKEDSGKVIVKVKKEGINLIIEVADNGIGMNE-KKLEELYANLNNPLYDKSIGLKNVYR 573 Query: 539 RLKLCFQDRFMFAMDA 554 RL L + D F +++ Sbjct: 574 RLMLYYNDNAEFYIES 589 >A4XMX5.1 A4XMX5_CALS8 Integral membrane sensor signal transduction histidine kinase Length = 613 Score = 270 bits (690), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 169/562 (30%), Positives = 287/562 (51%), Gaps = 28/562 (4%) Query: 21 SVFIPIVLTNVVFYNVTTSNLRNQKIRDADMALDNLKNELRVTIDQGVGLAYSLYGDSIF 80 V IP ++T+ +F NL+ QKI + L ++ +++ + + +LY D + Sbjct: 39 CVLIPTIVTHFIFTLFIVKNLQQQKIDQIKGVFNILNANIKKVLEEAILYSNTLYTDELL 98 Query: 81 NKTITRKFTSEKDYVETFNSYLRGAL-ADQNV-QGVRWYQVYTDNPTVLASGYIDRLTDK 138 N + + +D+ + YLR + +NV + +YT+NPT++ S + D Sbjct: 99 NDMLDIGYRGLEDFYSNYEGYLRNRIYQGRNVYSNIARVTIYTNNPTIVDSDGYRKFNDG 158 Query: 139 LRDTGWYT---QSKASSSRYPTF---IYSEQKF-SLIQKLNNY--------HTSGIEQLV 183 W++ ++ PT + E+ + SL + LN + + S ++ Sbjct: 159 -EAKEWFSLVMDNQQGIIVIPTVDEGVNGEEGYVSLFRNLNQFERRSTSRGNNSKYLKIA 217 Query: 184 KIDLNMERIHQIFFGSAFNGMVYLVDPQGRVQYGNDTAKLPEGVPFKEISYPKNFLAFKN 243 KID+ + F G +YL+D R+ + PF I + K K+ Sbjct: 218 KIDMYLSSFFNSINFEIFGGEIYLLDKSNRIIAARSNNSVIFAKPF--IKFDKRKFVSKD 275 Query: 244 VY-----SGINYLEGWTLEGVIDEENVLKEVRKSRSFVIWLACINFVLPSIIIAAMSRSI 298 Y N L W L GV + +L+E+ ++ ++++++ ++ + +++I ++ S+ Sbjct: 276 SYIFEEKLDYNLLSSWKLVGVFSKSYMLREIYRAIEYILFISVLSLLFATLLIRMITSSL 335 Query: 299 HVRLVRILKHMKKVKAQNFQTIPHEEARDEIGQLTIEFNRMTETVNSLINEVYLADIQKK 358 RL + +H+KK++ QNF+ + +E DEIG + EFN MT + LI + L++IQ+K Sbjct: 336 SARLELLTRHIKKIRKQNFEILNCKEGNDEIGNVIKEFNNMTIKLKELIEKEMLSEIQRK 395 Query: 359 NLELKXXXXXXXXXXSQINPHFLFNSLESVRMRSLIKGEKETAKIIQHMAKMFRKSVSWS 418 LE++ SQINPHFLFN+L+S+RMRS++K E ETA+II+++ + R+ + W Sbjct: 396 TLEIEKKQAELNALQSQINPHFLFNTLDSIRMRSVLKNELETAEIIKYLTRTLRRLIYWG 455 Query: 419 HNYVTVREELELIESFLTIQQYRFGDKLEYSIVADPAALEHRIPKMVLLPFVENASIHGI 478 ++ TV EE+ +E FL IQ+YR G+KL Y I D A IPKM + P VENA IHGI Sbjct: 456 NDITTVEEEIGFVEDFLKIQKYRLGEKLAYRIYVDEVARNCLIPKMTIQPLVENACIHGI 515 Query: 479 ESSPDKGIIVISVAVQRDRLIFRLEDNGIGMSPXXXXXXXXXXXXNDDIGERVGMKNAYY 538 E G I+I V + LI ++EDNGIGM N+ + +G+KN Y Sbjct: 516 EEIEGNGEIIIEVKKEEAYLIIKVEDNGIGMDE-EKLSQLYENLSNNTYEKNIGLKNVYK 574 Query: 539 RLKLCFQDRFMFAMDA--REGT 558 RL L + + F + + ++GT Sbjct: 575 RLMLYYNNAVDFKIHSNFKQGT 596 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.137 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,875,034,176 Number of extensions: 114480115 Number of successful extensions: 302086 Number of sequences better than 1.0e-05: 1910 Number of HSP's gapped: 299693 Number of HSP's successfully gapped: 1910 Length of query: 563 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 422 Effective length of database: 1,732,333,088 Effective search space: 731044563136 Effective search space used: 731044563136 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 134 (56.2 bits)