BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0415.0005.p (449 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q2L5V5.1 Q2L5V5_CLOPE Sensor protein EC=2.7.13.3 537 e-151 B1RK42.1 B1RK42_CLOPE Sensor protein EC=2.7.13.3 537 e-151 B5CKS0.1 B5CKS0_9FIRM Sensor protein EC=2.7.13.3 172 8e-41 C0CLA5.1 C0CLA5_9FIRM Sensor protein EC=2.7.13.3 157 2e-36 Q5WIR1.1 Q5WIR1_BACSK Sensor protein EC=2.7.13.3 157 3e-36 >Q2L5V5.1 Q2L5V5_CLOPE Sensor protein EC=2.7.13.3 Length = 443 Score = 537 bits (1384), Expect = e-151, Method: Compositional matrix adjust. Identities = 254/442 (57%), Positives = 316/442 (71%) Query: 1 MAKRHRSVSLSFVLFRFAIVMLGCMLLCCLAWYVVMVRLQTTGIIYQGAVSNQQVEQMLA 60 MAKR S+SLSFVL RF I+MLGCML C + W + L+ IY G+VSNQQVE+MLA Sbjct: 1 MAKRQNSISLSFVLLRFTIIMLGCMLSCFIIWLTTLQLLEKKDFIYHGSVSNQQVEKMLA 60 Query: 61 GEPKTFVSPGDDFLAEYALFGRNGEVLDSNVKKKKLEVLTGFLQGDAYSINVSRYTYTDG 120 G+P F+SP ++FLA+YALF ++GE+L+SNV+ K+LE+LT +L+ + I+ RYTY D Sbjct: 61 GKPLNFISPNNNFLAKYALFNKSGEILESNVEGKELEILTMYLKENINDIHSLRYTYQDE 120 Query: 121 STVIFRWHYRAEFVNPVLRGMLPPAEYXXXXXXXXXXXXXXXFNTLWXXXXXXXXXXXFS 180 ST++ RW+YR EF+NP LR +LPP EY FNTLW FS Sbjct: 121 STIVIRWNYRREFINPTLRNILPPFEYLWWGTLGIAWILCLIFNTLWLRYNLATKLKLFS 180 Query: 181 EVSGKVGAQDLDFAIPHAGIREYDQALGAMEHMREALYSSLSSXXXXXXXXXXXXXXXXH 240 +VS KV +Q+L+F IPHAGIREYDQAL AMEHMR+ALY+SLS H Sbjct: 181 QVSEKVASQELEFEIPHAGIREYDQALDAMEHMRKALYTSLSLQWAAKQERESEIESLAH 240 Query: 241 DLKTPLTLVGGNAELLLDEELPERSRKMVETIMASNDRAKQYVASLLETSAGADEAFENT 300 DLKTPLTL+GGNAELLL E+LP+ + KMV+TI++SNDRAK YV SLLE S G DE FE Sbjct: 241 DLKTPLTLIGGNAELLLYEDLPDNTLKMVKTIISSNDRAKNYVVSLLEASIGIDEEFEKI 300 Query: 301 SLPAMFDELCQSTMAIAEAKRVCLQTRNGLEGAAGIQKDHLLRALGNVVQNAIEHTPAGG 360 L + D+L Q+TM IAE K++ LQ +N L+G A IQ++ LLRALGN+VQNAIEHT AG Sbjct: 301 RLYDLLDKLYQNTMPIAENKKIYLQKKNKLDGIANIQEERLLRALGNIVQNAIEHTNAGR 360 Query: 361 NVYLEGSMADGGWQVTVCDEGPGFSKAALHHATERLWRGDAARGADGHSGLGLWFAAQVA 420 NVYLEG M +GGWQ+ V DEGPGFSKAAL HAT+RLWR D AR H+G+GLWFA QV Sbjct: 361 NVYLEGKMINGGWQIIVRDEGPGFSKAALQHATKRLWRDDTARAKSNHNGIGLWFALQVV 420 Query: 421 KTHAGQLELRNCASGGVVTIQF 442 K H+GQ++L+N GG+VTI+F Sbjct: 421 KMHSGQIKLQNYDCGGLVTIEF 442 >B1RK42.1 B1RK42_CLOPE Sensor protein EC=2.7.13.3 Length = 443 Score = 537 bits (1384), Expect = e-151, Method: Compositional matrix adjust. Identities = 254/442 (57%), Positives = 316/442 (71%) Query: 1 MAKRHRSVSLSFVLFRFAIVMLGCMLLCCLAWYVVMVRLQTTGIIYQGAVSNQQVEQMLA 60 MAKR S+SLSFVL RF I+MLGCML C + W + L+ IY G+VSNQQVE+MLA Sbjct: 1 MAKRQNSISLSFVLLRFTIIMLGCMLSCFIIWLTTLQLLEKKDFIYHGSVSNQQVEKMLA 60 Query: 61 GEPKTFVSPGDDFLAEYALFGRNGEVLDSNVKKKKLEVLTGFLQGDAYSINVSRYTYTDG 120 G+P F+SP ++FLA+YALF ++GE+L+SNV+ K+LE+LT +L+ + I+ RYTY D Sbjct: 61 GKPLNFISPNNNFLAKYALFNKSGEILESNVEGKELEILTMYLKENINDIHSLRYTYQDE 120 Query: 121 STVIFRWHYRAEFVNPVLRGMLPPAEYXXXXXXXXXXXXXXXFNTLWXXXXXXXXXXXFS 180 ST++ RW+YR EF+NP LR +LPP EY FNTLW FS Sbjct: 121 STIVIRWNYRREFINPTLRNILPPFEYLWWGTLGIAWILCLIFNTLWLRYNLATKLKLFS 180 Query: 181 EVSGKVGAQDLDFAIPHAGIREYDQALGAMEHMREALYSSLSSXXXXXXXXXXXXXXXXH 240 +VS KV +Q+L+F IPHAGIREYDQAL AMEHMR+ALY+SLS H Sbjct: 181 QVSEKVASQELEFEIPHAGIREYDQALDAMEHMRKALYTSLSLQWAAKQERESEIESLAH 240 Query: 241 DLKTPLTLVGGNAELLLDEELPERSRKMVETIMASNDRAKQYVASLLETSAGADEAFENT 300 DLKTPLTL+GGNAELLL E+LP+ + KMV+TI++SNDRAK YV SLLE S G DE FE Sbjct: 241 DLKTPLTLIGGNAELLLYEDLPDNTLKMVKTIISSNDRAKNYVVSLLEASIGIDEEFEKI 300 Query: 301 SLPAMFDELCQSTMAIAEAKRVCLQTRNGLEGAAGIQKDHLLRALGNVVQNAIEHTPAGG 360 L + D+L Q+TM IAE K++ LQ +N L+G A IQ++ LLRALGN+VQNAIEHT AG Sbjct: 301 RLYDLLDKLYQNTMPIAENKKIYLQKKNKLDGIANIQEERLLRALGNIVQNAIEHTNAGR 360 Query: 361 NVYLEGSMADGGWQVTVCDEGPGFSKAALHHATERLWRGDAARGADGHSGLGLWFAAQVA 420 NVYLEG M +GGWQ+ V DEGPGFSKAAL HAT+RLWR D AR H+G+GLWFA QV Sbjct: 361 NVYLEGKMINGGWQIIVRDEGPGFSKAALQHATKRLWRDDTARAKSNHNGIGLWFALQVV 420 Query: 421 KTHAGQLELRNCASGGVVTIQF 442 K H+GQ++L+N GG+VTI+F Sbjct: 421 KMHSGQIKLQNYDCGGLVTIEF 442 >B5CKS0.1 B5CKS0_9FIRM Sensor protein EC=2.7.13.3 Length = 458 Score = 172 bits (435), Expect = 8e-41, Method: Compositional matrix adjust. Identities = 109/446 (24%), Positives = 205/446 (45%), Gaps = 13/446 (2%) Query: 1 MAKRHRSVSLSFVLFRFAIVMLGCMLLCCLAWYVVMVRLQTTGIIYQGAVSNQQVEQ--- 57 M + RS +LS + R+ +VMLG ++ + Y+++ L + G IY + Q++ + Sbjct: 1 MGRVKRSNALSRIFMRYVLVMLGSLVGLVIVAYLLLYLLISVGCIYPANYAEQKINEAYD 60 Query: 58 --MLAGEPKTFVSPGDDFLAEYALFGRNGEVLDSNVKKKKLEVLTGFLQ-GDAYSINVSR 114 + A + + P L +Y +F NGE + ++ ++ ++ + G+A + Sbjct: 61 TILRADKVTAEMIPA---LCDYVIFSENGEKIGGDLSEQYEQIAWNVAKYGNASGKYFYK 117 Query: 115 YTYTDGSTVIFRWHYRAEFVNPVLRGMLPPAEYXXXXXXXXXXXXXXXFNTLWXXXXXXX 174 + V+ ++ ++ + LR + ++ Sbjct: 118 VIVRENEYVVLQYRLTPQYHSAFLREHFIGPQNVMIIMSVIGAVAIIIIPSIRFGKRIKK 177 Query: 175 XXXXFSEVSGKVGAQDLDFAIPHAGIREYDQALGAMEHMREALYSSLSSXXXXXXXXXXX 234 + G++ Q+L++ +GI+E+D L A++ MR+AL SL Sbjct: 178 QMQPVLDAIGQIKDQNLEYETSCSGIKEFDDCLSAIDDMRDALRESLEKQWKTEQEKKQQ 237 Query: 235 XXXXXHDLKTPLTLVGGNAELLLDEELPERSRKMVETIMASNDRAKQYVASLLETSAG-- 292 HD+KTPLT+V GNAELL + EL +K + ++ + + YV L++ + Sbjct: 238 MSALAHDIKTPLTIVRGNAELLSETELTTEQKKNITYVLNGTTQIQSYVKQLIDVTKSWN 297 Query: 293 -ADEAFENTSLPAMFDELCQSTMAIAEAKRVCLQTRNGL-EGAAGIQKDHLLRALGNVVQ 350 +D + L F ++ + + + E+ + + G + I D + RA+ N++Q Sbjct: 298 CSDVTYTTVRLEDFFADIKEQALGLVESYHQKIDWKAGQSDKKVTIAYDPMFRAVMNMIQ 357 Query: 351 NAIEHTPAGGNVYLEGSMADGGWQVTVCDEGPGFSKAALHHATERLWRGDAARGADGHSG 410 NA+EHT G +Y++ DG V D G GF+K AL H TE+ + D +R + H G Sbjct: 358 NAVEHTKENGIIYIDAKEQDGRLTFIVEDSGSGFTKEALLHGTEQFFMDDTSRNGEAHYG 417 Query: 411 LGLWFAAQVAKTHAGQLELRNCASGG 436 +GL+FA VA+ + G ++L N + G Sbjct: 418 MGLFFAKTVAEKYGGGIKLSNSENTG 443 >C0CLA5.1 C0CLA5_9FIRM Sensor protein EC=2.7.13.3 Length = 472 Score = 157 bits (397), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 139/463 (30%), Positives = 207/463 (44%), Gaps = 25/463 (5%) Query: 1 MAKRH--RSVSLSFVLFRFAIVMLGCML-LCCLAWYVVMVRLQTTGIIYQGAV--SNQQV 55 M KR R LS + +R+ +V G M+ +C + W++ +V + G +YQ +V N Q Sbjct: 1 MVKRRADRKWKLSSLFWRY-LVTTGVMVAVCTVLWWMAVVACISVGFVYQASVGARNLQK 59 Query: 56 EQMLAGEPKTFVSPGDDFLAEYALFGRNGEVLDSNVKKKKLEVLTGFLQGD------AYS 109 Q + F F ++ L +G VL + + +K L+ ++GD YS Sbjct: 60 TQERLLRQEEFQGEEIPFYYDWCLVSEDGTVLQAKMSEKVLKQAKN-VEGDDGMRVFPYS 118 Query: 110 INVSRYTYTDGSTVIFRWHYRAEFVNPVLRGMLPPAEYXXXXXXXXXXXXXXXFNTLWXX 169 + DGS + + Y +VNP+L+ LP + T Sbjct: 119 KFFHAVSLKDGSRCVLAYDYSMPYVNPMLQRYLPDFQVTATLLLFVCWGVIAVTRTRKYT 178 Query: 170 XXXXXXXXXFSEVSGKVGAQDLDFAI-PHAGIREYDQALGAMEHMREALYSSLSSXXXXX 228 + V +Q LD I P IRE + AL +E +R L +SLS Sbjct: 179 KILQNDTRAVRAAADLVASQRLDEPILPEGKIRELNDALETIEKLRVELAASLSRQWAME 238 Query: 229 XXXXXXXXXXXHDLKTPLTLVGGNAELLLDEELPERSRKMVETIMASNDRAKQYVASLLE 288 HDLKTPLT++ GNAELL +EEL VE I+ ++YV L Sbjct: 239 EQRNQELASLSHDLKTPLTVIRGNAELLEEEELASWQEASVEAILRGTLHLEEYVQELRS 298 Query: 289 TSAGADEAFEN-TSLP-AMFDELCQST-MAIAEAKRVCLQTRNGLEGAAGI--------Q 337 +AG+ E+ E LP F E C+ A+ AK++ L+ G E A Q Sbjct: 299 VAAGSGESSEEFRKLPLKKFIERCREDGEALCAAKKISLKVCMGEEVARQSEEGFSFRGQ 358 Query: 338 KDHLLRALGNVVQNAIEHTPAGGNVYLEGSMADGGWQVTVCDEGPGFSKAALHHATERLW 397 + LLRA+ N++ NA+ + G + LE DG TV D GPGF + AL A + + Sbjct: 359 EMQLLRAIRNLIDNAVRFSKEGQEIVLEVQEKDGRLIFTVQDSGPGFCQEALAKAGKIFY 418 Query: 398 RGDAARGADGHSGLGLWFAAQVAKTHAGQLELRNCASGGVVTI 440 + R ++GH GLGL+F +VA H G L++ N GG T+ Sbjct: 419 TSEKHRASEGHLGLGLYFCCKVAARHGGGLKIENGEKGGRATL 461 >Q5WIR1.1 Q5WIR1_BACSK Sensor protein EC=2.7.13.3 Length = 467 Score = 157 bits (396), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 121/446 (27%), Positives = 195/446 (43%), Gaps = 16/446 (3%) Query: 17 FAIVMLGCMLLCCLAWYVVM-VRLQTTGIIYQGAVSNQQVEQMLAGEPKTFVSPGDDFLA 75 F ++ LG L A Y+++ + G +Y ++ E L +T D+ + Sbjct: 16 FYMLTLGVSLTTVAALYLLLHIIALNAGFVYPANHYEREAEN-LRPSLETVEQVTDNMIP 74 Query: 76 E---YALFGRNGEV-LDSNVKKKKLEVLTGFLQGDAYSINVSRYTYT-----DGSTVIFR 126 E YA+F + V + K L+ + L + Y+ ++ + Y D VI Sbjct: 75 EMMSYAIFDKELNVKTKGTLSDKSLQTVQSMLTNEPYTNHIRQTGYMVVERPDEIGVI-E 133 Query: 127 WHYRAEFVNPVLRGMLPPAEYXXXXXXXXXXXXXXXFNTLWXXXXXXXXXXXFSEVSGKV 186 + RAEF +P LR LP E T ++ ++ Sbjct: 134 YPLRAEFRSPFLRQHLPNYELTSIALLVILLIATAFAVTTHFANRMKKQFKKLHSITKQI 193 Query: 187 GAQDLDFAIPHAGIREYDQALGAMEHMREALYSSLSSXXXXXXXXXXXXXXXXHDLKTPL 246 Q+LDF + I+E+D+ + ++ M+++L SL++ HDLK P+ Sbjct: 194 QEQNLDFTPEFSKIKEFDEIIDSLLEMKQSLQHSLNTQWHMEKAKGEQIGALAHDLKIPV 253 Query: 247 TLVGGNAELLLDEELPERSRKMVETIMASNDRAKQYVASLLE---TSAGADEAFENTSLP 303 T++ GNAELL E I+ + + +QY++ L+ T T L Sbjct: 254 TVIKGNAELLSLSGQQEEQSAYTHYILNAVHKIEQYISQLIHLSHTDGSLPLTLRKTDLA 313 Query: 304 AMFDELCQSTMAIAEAKRVCLQTRNGLEGAAGIQKDHLLRALGNVVQNAIEHTPAGGNVY 363 + L A +K V + + AA I + L RAL N+V NAI++TP G+++ Sbjct: 314 PFVEMLLADASAYKGSKNVKIVCQKNELTAAEIDQHLLHRALLNIVTNAIDYTPEQGSIF 373 Query: 364 LEGSMADGGWQVTVCDEGPGFSKAALHHATERLWRGDAARGADGHSGLGLWFAAQVAKTH 423 +E + + TV D G GFS AL ATE + + +R + H G+GL FA+ VAK H Sbjct: 374 IEAACTPTTFHFTVMDTGKGFSAEALKRATELFFMEEKSRHTNNHYGIGLTFASNVAKLH 433 Query: 424 AGQLELRNCAS-GGVVTIQFPGTIRN 448 G L + N AS GG V + P T +N Sbjct: 434 NGSLSIENAASGGGSVYVAIPITAKN 459 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,378,978,657 Number of extensions: 91800490 Number of successful extensions: 264185 Number of sequences better than 1.0e-05: 7563 Number of HSP's gapped: 263699 Number of HSP's successfully gapped: 7566 Length of query: 449 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 310 Effective length of database: 1,751,175,118 Effective search space: 542864286580 Effective search space used: 542864286580 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)