BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0412.0010.p (421 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DGY0.1 B1DGY0_9BACL Two component transcriptional regulator, A... 239 3e-61 B3K996.1 B3K996_9BACI Response regulator receiver 154 1e-35 C0FJU4.1 C0FJU4_9CLOT Putative uncharacterized protein 139 7e-31 C5EEW4.1 C5EEW4_9FIRM Two-component response regulator 137 3e-30 A8MJM2.1 A8MJM2_ALKOO Two component transcriptional regulator, A... 136 5e-30 >B1DGY0.1 B1DGY0_9BACL Two component transcriptional regulator, AraC family Length = 356 Score = 239 bits (610), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 135/357 (37%), Positives = 196/357 (54%), Gaps = 13/357 (3%) Query: 62 IKVLLVDDESWNRDIVRTFGSWEEHGMEIAGEAEDGREALRLTDELSPQIVITDMRMPGA 121 +K +++DDE W RD ++ WE G+E EAE+G LR+ +E+ P IVITDMRM G Sbjct: 1 MKAVIIDDEFWTRDSIKRLADWERFGIEQVEEAEEGLSGLRIINEIHPDIVITDMRMRGM 60 Query: 122 DGVMLMNNLHARYPEIKVIVVSGYDDFKYAQNAVRYGAVDYLLKPVDPKELNAVLDKCRR 181 DG L+ L YP I+ IV+SG+DDF Y + A+ +Y+LKPV +ELN L+K Sbjct: 61 DGAELLKKLTEDYPFIRKIVISGFDDFAYTKQAILSRVDEYILKPVQAEELNRALEKAVS 120 Query: 182 ELEEAERGQKAYALDIDVSLCLSSYKQLMRVHFNELNAEGVNSVLEGIRRELELGGAKGP 241 EL A A +D D+ ++ YK+ + F EL AE V + L L P Sbjct: 121 ELRIARGLHAAQPMDKDLMSVVTEYKEQISRQFQELRAEDVRESFARLETLLRLQANTAP 180 Query: 242 GALRQAANEMLLLLKELMRGNRLEDELLKAEISHEALASAANVE--------AYLKALYG 293 G +LLL ELM ++ A+ E AS + L++ YG Sbjct: 181 GLHHLLYKHFMLLLDELMAKAGIDS----AKALPEQAASFFVTDFTPLGQWIGMLRSSYG 236 Query: 294 AALELLIGQRKFKNKLKLDEVRLYIDGHFAEAVTLDGLARAFFVSKEYLSKVFKQEYGCN 353 A LE I R+ K+++ ++ +R +I+ FAE +TL+ +A +FVSKE+LS+ FKQ G Sbjct: 237 AVLEQTIQLRQSKHRIDIEHIRQFINRSFAEPITLESIASLYFVSKEHLSRTFKQATGST 296 Query: 354 VTDYILGLRMEKAKEWLADENIPIKTVAELAGYEDVGYFYRVFKKHYGVAPGEMRKQ 410 V DYI+ R+E+A L ++ IK AE GY D+ YF+R+FKK G+ P + RK+ Sbjct: 297 VMDYIVTKRVEEANRLL-QSSVSIKNAAEAVGYSDLTYFHRIFKKVTGITPAQARKE 352 >B3K996.1 B3K996_9BACI Response regulator receiver Length = 353 Score = 154 bits (390), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 105/362 (29%), Positives = 186/362 (51%), Gaps = 20/362 (5%) Query: 61 MIKVLLVDDESWNRDIVRTFGSWEEHGMEIAGEAEDGREALRLTDELSPQIVITDMRMPG 120 M +++++DDE +R +E+AGEAEDG EAL + + P I++TD+ MP Sbjct: 1 MYRIMMIDDEYAIHLSLRKLVERSGLRIEVAGEAEDGVEALEMLENSRPDIIVTDICMPE 60 Query: 121 ADGVMLMNNLHARYPEIKVIVVSGYDDFKYAQNAVRYGAVDYLLKPVDPKELNAVLDKCR 180 DG+ + + + ++ I++SG+D+F++A+ A+RYG D+LLKP+DP + +A L++ Sbjct: 61 MDGLEFIRRVRESHAQMHFIILSGHDNFEFARQAMRYGVSDFLLKPIDPAQFHATLERAC 120 Query: 181 RELEEAERGQKAYALDIDVSLCLSSYK-QLMRVHFNELNAEGVNSVLEGIRRELELGGAK 239 REL+E + ++ +L +K +L + ++ E + E I E G K Sbjct: 121 RELDER---KARFSRQTKWTLAQQRHKARLAELLWSAEEREALEQTHE-IMALFETMGPK 176 Query: 240 GPGALRQAANEMLLLLKELMRGNRLEDELLKAEISHE------ALASAANVEAYLKALYG 293 R A +L+ EL+ +L + E LA E +K + Sbjct: 177 EVSLSRYAH----MLISELLSALEERGLMLNMDTGEEQWAQDDPLACRRQTEDKVKEM-- 230 Query: 294 AALELLIGQRKFKNKLKLDEVRLYIDGHFA-EAVTLDGLARAFFVSKEYLSKVFKQEYGC 352 L L+ G R ++ + + + +I+ ++A E ++L +A + +S YLS+ FK E Sbjct: 231 --LALIKGSRNLGSRHNIQKAKRFIEENYAMEDLSLQEVADSVGMSVTYLSRTFKSETNM 288 Query: 353 NVTDYILGLRMEKAKEWLADENIPIKTVAELAGYEDVGYFYRVFKKHYGVAPGEMRKQNS 412 N Y++ +RMEKA+E LA+ + + A G+ D +F + FKK +G+ P RKQ Sbjct: 289 NFVKYLVQVRMEKARELLAESELSAQEAAYRVGFSDYVHFSKTFKKFHGLTPSAYRKQCK 348 Query: 413 SL 414 ++ Sbjct: 349 AM 350 >C0FJU4.1 C0FJU4_9CLOT Putative uncharacterized protein Length = 369 Score = 139 bits (349), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 109/372 (29%), Positives = 180/372 (48%), Gaps = 33/372 (8%) Query: 61 MIKVLLVDDESWNRDIVRTFGSWEEHGMEIAGEAEDGREALRLTDELSPQIVITDMRMPG 120 MIKV LV+DE R +R W +G + GE DG A L E+ P I++TD++MP Sbjct: 1 MIKVFLVEDEPIIRKGIRDNIDWAANGFQFVGEGGDGEYAYPLILEMEPDILVTDVKMPF 60 Query: 121 ADGVMLMNNLHARYPEIKVIVVSGYDDFKYAQNAVRYGAVDYLLKPVDPKELNAVLDKCR 180 DG+ L + P+IK++++SGY++F YA+ A++ G DY+LKPV L L + Sbjct: 61 MDGLELSRLVKKALPDIKIVILSGYNEFDYAKEAIKMGISDYILKPVTSAALVEALKRV- 119 Query: 181 RELEEAERGQKAYALDIDVSLCLSSYKQLMRVHFNELNAEGVNSVLEGIRRELELG---- 236 A+ ++ + + +SYK+ ++ + GV+ L I L+LG Sbjct: 120 -----ADTIREEREREKLLERYFASYKKYTE-FLDQTDYRGVDRRL--IEEFLKLGSVDE 171 Query: 237 ---------GAKGPG-----ALRQ-AANEMLLLLKELMRGNRLEDELLKA--EISH--EA 277 A G LRQ ++ ++E +R +E+EL ++ +I +A Sbjct: 172 CETFVEEYFAAVGENNYKSLLLRQYMVVDIFYCVQEFVRNLGIEEELPESFRDIKRIPQA 231 Query: 278 LASAANVEAYLKALYGAALELLIGQRKFKNKLKLDEVRLYIDGHFAEA-VTLDGLARAFF 336 + + YL L+G ALE+ + + E + +I +F+ +L+ +A Sbjct: 232 ITEVEKTKHYLVGLFGCALEVRDRVSSDRYGQVIREAKSFIKENFSRGDFSLNLVAAHIG 291 Query: 337 VSKEYLSKVFKQEYGCNVTDYILGLRMEKAKEWLADENIPIKTVAELAGYEDVGYFYRVF 396 VS Y S +F+QE G +Y+ +R++ A E L N+ + E AGY D YF F Sbjct: 292 VSPSYFSSIFRQETGQTFVEYLTRVRIDSACEMLKCTNLRTAEIGERAGYNDPHYFSSAF 351 Query: 397 KKHYGVAPGEMR 408 KK G++P E + Sbjct: 352 KKVMGMSPKEYK 363 >C5EEW4.1 C5EEW4_9FIRM Two-component response regulator Length = 331 Score = 137 bits (344), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 101/361 (27%), Positives = 171/361 (47%), Gaps = 51/361 (14%) Query: 56 ERNDSMIKVLLVDDESWNR----DIVRTFGSWEEHGMEIAGEAEDGREALRLTDELSPQI 111 +R+ +++L+ DDE +R ++R + W EA DGREA+ EL + Sbjct: 2 QRSAGHMRILIADDEMISRATIQRMIRNYCPWAGQ----VKEASDGREAVEKAMELDADV 57 Query: 112 VITDMRMPGADGVMLMNNLHARYPEIKVIVVSGYDDFKYAQNAVRYGAVDYLLKPVDPKE 171 V+ D+ MP DG+ L +I ++ + F+YA+ A+ GA ++L+KPVDP E Sbjct: 58 VLMDIEMPELDGMEAARRLRQWKEGCVIIFLTAFATFQYAKQAISLGATEFLVKPVDPCE 117 Query: 172 LNAVLDKCRRELEEAERGQKAYALDIDVSLCLSSYKQLMRVHFNELNAEGVNSVLEGIRR 231 L VL++ R ++ G A D + + + N AEG G+R Sbjct: 118 LKKVLERVRERVDGTAGGMGRTAEDRNPA------------YGNRECAEGA-----GVRA 160 Query: 232 ELELGGAKGPGALRQAANEMLLLLKELMRGNRLEDELLKAEIS--HEALASAANVEAYLK 289 E A+G GA + A G R E + AE + H + + + ++ +K Sbjct: 161 ECAGVRAEGAGARVEGA------------GVRAECSGVHAEGAGIHISDSGSHTLDEAIK 208 Query: 290 ALYGAALELLIGQRKFKNKLKLDEVRLYIDGHFAEAVTLDGLARAFFVSKEYLSKVFKQE 349 + A+++ E + Y+D H+ + + +D +AR F VS Y +K+FKQ Sbjct: 209 SFGARAVKIS------------QEGKQYMDLHYMDDIGVDTMARMFQVSANYFNKMFKQA 256 Query: 350 YGCNVTDYILGLRMEKAKEWLADENIPIKTVAELAGYEDVGYFYRVFKKHYGVAPGEMRK 409 Y + +Y++ +R+ A E+L + + I+ + GYED YF R+FKK G+ P E R Sbjct: 257 YSISSKEYLINIRVGHAMEYLKNPALTIREAGIMVGYEDSNYFTRIFKKKTGMTPIEYRN 316 Query: 410 Q 410 + Sbjct: 317 K 317 >A8MJM2.1 A8MJM2_ALKOO Two component transcriptional regulator, AraC family Length = 371 Score = 136 bits (342), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 106/368 (28%), Positives = 193/368 (52%), Gaps = 27/368 (7%) Query: 61 MIKVLLVDDESWNRDIVRTFGSW-EEHGMEIAGEAEDGREALRLTDELSPQIVITDMRMP 119 M KV++VDD R ++ W EE G I EAEDG++AL + S ++ITD++MP Sbjct: 1 MYKVMIVDDMEIIRRQIKRLPLWGEETGFHIVEEAEDGKDALDKLQKQSVDLLITDIKMP 60 Query: 120 GADGVMLMNNLHARYPEIKVIVVSGYDDFKYAQNAVRYGAVDYLLKPVDPKELNAVLDKC 179 DGV L+ + V+ +S + +F +A+ A++YG DYL+KPV +EL +L K Sbjct: 61 RIDGVELLKEVDEHQLARCVVFLSEHSEFSFAKEAIQYGIFDYLVKPVQREELQKLLLKA 120 Query: 180 RRELEEAERGQKAYALDIDVSLCLSSYKQLMRVHFNELNAEGVNSVLEGIRRELELGGAK 239 ++ +EE ER +++ ++ L + + V++ E + E + + + L + Sbjct: 121 QQYIEE-EREKESQLKKLEDRLS-----EKLEVYYPEHHIESIIQYISAGDAQQALPAIE 174 Query: 240 ------GPGALRQAANEMLLLLK---ELMRG-----NRLEDELLKAEISHEALASAANVE 285 G R +LL K E+++G L+ + KA + + L + ++E Sbjct: 175 AMVTDTGAALERDPIKTAVLLEKSYGEILKGIYQHHQWLDQFVDKALLVNINLTNCGDIE 234 Query: 286 AYLKALYGAALELL---IGQRKFKNKLK--LDEVRLYIDGHFAEAVTLDGLARAFFVSKE 340 A +K AAL +L I Q + K + E+ Y+ + +++++ ++ F++K Sbjct: 235 A-MKVHIVAALGILEATIAQLILRGKKSPLIAEICSYVLENVEQSISISTISEVLFLTKN 293 Query: 341 YLSKVFKQEYGCNVTDYILGLRMEKAKEWLADENIPIKTVAELAGYEDVGYFYRVFKKHY 400 Y+ +FKQE G + +YI ++ME+AK+ +A+ + VA+ GY+D YF ++FKK+ Sbjct: 294 YIGDLFKQETGMTIGEYITMVKMERAKQLIAEGTLRNYEVADRLGYKDAEYFGKLFKKNV 353 Query: 401 GVAPGEMR 408 G++P E + Sbjct: 354 GLSPMEFK 361 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.136 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,293,249,150 Number of extensions: 100247385 Number of successful extensions: 348988 Number of sequences better than 1.0e-05: 13413 Number of HSP's gapped: 361446 Number of HSP's successfully gapped: 14006 Length of query: 421 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 283 Effective length of database: 1,760,596,133 Effective search space: 498248705639 Effective search space used: 498248705639 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)