BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0407.0016.p (451 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A6TX80.1 A6TX80_ALKMQ Sensor protein EC=2.7.13.3 280 2e-73 A6LYQ4.1 A6LYQ4_CLOB8 Sensor protein EC=2.7.13.3 225 7e-57 A7VSL8.1 A7VSL8_9CLOT Sensor protein EC=2.7.13.3 220 2e-55 B2TPP4.1 B2TPP4_CLOBB Sensor protein EC=2.7.13.3 219 3e-55 B2UXX0.1 B2UXX0_CLOBA Sensor protein EC=2.7.13.3 218 1e-54 >A6TX80.1 A6TX80_ALKMQ Sensor protein EC=2.7.13.3 Length = 481 Score = 280 bits (716), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 167/466 (35%), Positives = 259/466 (55%), Gaps = 25/466 (5%) Query: 1 MRFWQKTXXXXXXXXXXXXXXXXIMIMNKSWRLNMGREQQRAASDQALIANNIYENLNSI 60 M+FWQK + S+ LNM R++ RA + I N I E +NS Sbjct: 1 MKFWQKAFIGILIIFIVSINISSYLTSKHSFSLNMQRDKNRALGEYHFIRNGILEAINSN 60 Query: 61 KSRG-MRINDTILLDVARSYGEYYRERGISLELSNQ----------GTPVYAGPSE---- 105 R I + V RSY YYR++ + LEL + P G E Sbjct: 61 YYREEAEIPPASMESVMRSYANYYRKQDVFLELKHSNDLLFTNIPFSVPYSTGNEELDWN 120 Query: 106 ---------PSARYISVSNELPAPYGYLQLTYRREIEALYAGQDELNRYFVYINCISIPV 156 RY+ +S + + L Y R++ LY +L RY + ++ V Sbjct: 121 AVELQVLSINEKRYLYISGRVHGQHQDYALAYVRDLSELYDTHSQLIRYLITVSASVEIV 180 Query: 157 LAALMYVLIRKLTKPLKSLADSTKNIAEGNYSKRVQLQNRDEFGELAQHFNRMADAVERQ 216 L ++ + +RKLT+P++ + +T+ I+ G Y R+ + +DEF +LA++FN+MA +++ + Sbjct: 181 LTLVLLLFLRKLTQPIRIMQTATRKISSGVYDDRISIPGKDEFHDLAENFNQMASSIQEK 240 Query: 217 VTDLSAMAEEKQRMVDNLAHELRTPLTSLQGFAQYLNAAHIGEEERMTASGYLWSETLRL 276 +T+L A++KQR+VDNLAHELRTPLT+++G+ +YL A+ E+ R+ A+GY+ SET R+ Sbjct: 241 ITELDKNAQDKQRLVDNLAHELRTPLTAIRGYGEYLQNANASEQNRIKATGYIISETDRM 300 Query: 277 KNLVFKLLDLSILSHQPVERSRIPVVELFESVRRMEQANLDAAGLELILEADIPAVWGDR 336 +NL FKLLDL+++ + ++ RI EL +R + L ++L + + + + GD Sbjct: 301 QNLAFKLLDLALIKNSKLDVHRIIPSELLHQIRLVLAPKLKEKSIKLDIHSSLNELSGDF 360 Query: 337 ELLESFLVNCLENSIHASTPGSEIRLAAYEQETAAVLEVTDYGRGMSAGHLERVFEPFYR 396 LL+S LVN ++N++ AST S I L+AY + +LEV D+G GM V EPFYR Sbjct: 361 ILLQSLLVNLVDNAVKASTENSSIHLSAY-LDIVPILEVKDFGCGMDEEQTALVCEPFYR 419 Query: 397 VDHARSREHGGAGLGLALCRQIAEAHQAQLSLSSEEQKGTTIKLIL 442 VD ARSR GG GLGL+LCR+IA H AQL + S KGT+++++ Sbjct: 420 VDTARSRSSGGIGLGLSLCREIAHLHGAQLKIYSCLGKGTSVQILF 465 >A6LYQ4.1 A6LYQ4_CLOB8 Sensor protein EC=2.7.13.3 Length = 486 Score = 225 bits (574), Expect = 7e-57, Method: Compositional matrix adjust. Identities = 119/356 (33%), Positives = 213/356 (59%), Gaps = 6/356 (1%) Query: 90 LELSNQGTPVYAGPSEPSARYISVSNELPAPYGY-LQLTYRREIEALYAGQDELNRY--F 146 LE +QG Y + +Y+ S+ L Y Y +++ Y ++I +Y+ +++N+Y F Sbjct: 121 LENLSQGKTNYIIRTVDGKQYLYASS-LVNVYDYPIKVHYAKDISNIYS--EKINQYALF 177 Query: 147 VYINCISIPVLAALMYVLIRKLTKPLKSLADSTKNIAEGNYSKRVQLQNRDEFGELAQHF 206 + ++ + + A M+ + + +TKP+ +L ST+ I+ G YS+RV++++RDEF L+ +F Sbjct: 178 MKLDILICSLFAIFMFFISKLITKPINTLIASTQKISLGQYSERVKIKSRDEFSMLSSNF 237 Query: 207 NRMADAVERQVTDLSAMAEEKQRMVDNLAHELRTPLTSLQGFAQYLNAAHIGEEERMTAS 266 N MA +E ++ +L EK+ ++NL HEL+TPLTS+ G+A + + EE + AS Sbjct: 238 NLMAQTIEEKINELETSNIEKETFINNLTHELKTPLTSIIGYANLIRTSKYNEEVFVEAS 297 Query: 267 GYLWSETLRLKNLVFKLLDLSILSHQPVERSRIPVVELFESVRRMEQANLDAAGLELILE 326 Y++ E RL+ + FK++DL Q +E + + + V+R++ A L ++LI+E Sbjct: 298 DYIYKEGKRLEKMAFKMMDLIYAKTQEIELITERIFNVIDEVKRLQFARLKDKNIDLIIE 357 Query: 327 ADIPAVWGDRELLESFLVNCLENSIHASTPGSEIRLAAYEQETAAVLEVTDYGRGMSAGH 386 + + D++L+ L N +EN+I AS S+I + + + V D G G++ H Sbjct: 358 GEDCVLDIDKDLITMALSNLVENAIKASKNNSKIYIKICIIQNKTYISVVDLGLGIAKEH 417 Query: 387 LERVFEPFYRVDHARSREHGGAGLGLALCRQIAEAHQAQLSLSSEEQKGTTIKLIL 442 L+++++PFY VD ARSR++ GAG+GL++C++IAE H A + +SS+ GT + LI Sbjct: 418 LDKLWQPFYVVDKARSRKNNGAGIGLSICKKIAEVHSADIKISSDLGIGTEVTLIF 473 >A7VSL8.1 A7VSL8_9CLOT Sensor protein EC=2.7.13.3 Length = 478 Score = 220 bits (561), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 145/475 (30%), Positives = 247/475 (52%), Gaps = 43/475 (9%) Query: 1 MRFWQKTXXXXXXXXXXXXXXXXIMIMNKSWRLNMGREQQRAASDQALIANNIYENL--N 58 MRFWQK +++ + +LN +E + + + +++ ++ N+ Sbjct: 1 MRFWQKIFLISLAVLTVAVNTIAYLLIGNNHQLNKEKEIKSSVDEYSIVVSSFQTNVLYE 60 Query: 59 SIKSRGMRINDTILLDVARSYGEYYRERGISLELSNQGTPVYAG-----P---------- 103 +S ++DT + +AR + + + ++L+ V++ P Sbjct: 61 RYRSSEAELDDTQITQIAREFSYLFTLDNLYIQLNKGEERVFSNFTRDLPDNLYENVNQL 120 Query: 104 SEPSARYISVSNELPAPYGYLQ-----------LTYRREIEALYAGQDELNRYFVYINCI 152 SE AR + ++ Y Y+ T ++I +Y +++ R+F + I Sbjct: 121 SEGDARVLIRRDDDSRVYLYITSPVTIQSSNYFFTTIKDITNIYDVKNDQLRFFSVLGPI 180 Query: 153 SIPVLAALMYVLIRKLTKPLKSLADSTKNIAEGNYSKRVQLQNRDEFGELAQHFNRMADA 212 V+A +M +L + LT + L ST +A G Y+ ++++++DE GEL FN M +A Sbjct: 181 VSVVVAFIMLILSKLLTSRINRLRKSTMKVANGEYNA-IEIKSKDEIGELTADFNTMTEA 239 Query: 213 VERQVTDLSAMAEEKQRMVDNLAHELRTPLTSLQGFAQYLNAAHIGEEERMTASGYLWSE 272 V+++V L +A E++ +DN+ HE++TPLTS+ GF+ L +A + +E + ++ E Sbjct: 240 VKQKVEKLEDIASERKVFIDNMTHEMKTPLTSIIGFSDLLRSARLDDETVHDYAESIYKE 299 Query: 273 TLRLKNLVFKLLDLSILSHQP-VERSRIP--VVELFESVRRM---EQANLDAAGLELILE 326 LK++ KL+DL +L +P + +P V E+ ESVR + Q AA +E Sbjct: 300 GKYLKSISSKLMDLILLRQKPEMTEIDVPRLVEEIDESVRPIASSRQVAFSAASVE---- 355 Query: 327 ADIPAVWGDRELLESFLVNCLENSIHASTPGSEIRLAAY-EQETAAVLEVTDYGRGMSAG 385 + DREL++S L N ++N++ AS PG+ + L AY Q+ V D G G+ Sbjct: 356 ---AKLVCDRELIKSLLYNLIDNAVKASQPGTCVTLNAYFTQDGVMEFSVADQGSGIPKE 412 Query: 386 HLERVFEPFYRVDHARSREHGGAGLGLALCRQIAEAHQAQLSLSSEEQKGTTIKL 440 L+++FEPFYRVD ARSR++GGAGLGLALC +IA AH A L + SE +GT I+L Sbjct: 413 ELDKIFEPFYRVDKARSRKYGGAGLGLALCMEIAHAHAATLEIESEVGRGTVIRL 467 >B2TPP4.1 B2TPP4_CLOBB Sensor protein EC=2.7.13.3 Length = 485 Score = 219 bits (559), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 110/349 (31%), Positives = 206/349 (59%), Gaps = 4/349 (1%) Query: 96 GTPVYAGPSEPSARYISVSNELPAPYGYLQLTYRREIEALYAGQDELNRY--FVYINCIS 153 G Y + +Y+ VS+ + +++ Y ++I +Y +++N+Y F+ ++ + Sbjct: 128 GKTNYIIKTLDGKQYLYVSSLVNVYNVPIKIHYAKDISNIYI--EKMNQYALFMKLDILI 185 Query: 154 IPVLAALMYVLIRKLTKPLKSLADSTKNIAEGNYSKRVQLQNRDEFGELAQHFNRMADAV 213 + A M+ + R +TKP+ +L DST+ I+ G YS+RV+++++DEF L+ HFN MA + Sbjct: 186 CSLFAIFMFFVSRLITKPINTLIDSTQKISLGQYSERVRIKSKDEFNVLSNHFNLMAQTI 245 Query: 214 ERQVTDLSAMAEEKQRMVDNLAHELRTPLTSLQGFAQYLNAAHIGEEERMTASGYLWSET 273 E ++ +L EK+ ++NL HEL+TPLTS+ G+A + + EE ++ Y++ E Sbjct: 246 EDKINELEISNIEKETFINNLTHELKTPLTSIIGYANLIRTSKYNEELFFESADYIYKEG 305 Query: 274 LRLKNLVFKLLDLSILSHQPVERSRIPVVELFESVRRMEQANLDAAGLELILEADIPAVW 333 RL+ + FK++DL Q ++ + ++ + V++ ++LI+E + + Sbjct: 306 KRLEQMAFKMMDLIYAKTQEIKLTPEKIMPIIYEVKKSLLVKFKDKNIDLIVEEEDCILD 365 Query: 334 GDRELLESFLVNCLENSIHASTPGSEIRLAAYEQETAAVLEVTDYGRGMSAGHLERVFEP 393 D++L++ L N +EN+I AS S+I + + + V D G G++ HL+++++P Sbjct: 366 VDKDLIKIALCNLVENAIKASRNDSKIYIRVFVLNDKTFISVLDSGTGITKEHLDKIWQP 425 Query: 394 FYRVDHARSREHGGAGLGLALCRQIAEAHQAQLSLSSEEQKGTTIKLIL 442 FY VD ARSR++ GAG+GL++C++IAE H A + ++SE KGT + +I Sbjct: 426 FYVVDKARSRKNNGAGIGLSICKKIAEIHNADIKINSELGKGTEVTIIF 474 >B2UXX0.1 B2UXX0_CLOBA Sensor protein EC=2.7.13.3 Length = 485 Score = 218 bits (555), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 107/331 (32%), Positives = 195/331 (58%), Gaps = 3/331 (0%) Query: 112 SVSNELPAPYGYLQLTYRREIEALYAGQDELNRYFVYINCISIPVLAALMYVLIRKLTKP 171 S+ N AP +++ Y ++I +Y + F+ ++ + + A M+ + R +TKP Sbjct: 147 SIVNVYNAP---IKIHYAKDISNIYIEKTNQYALFMKLDILICSLFAVFMFFVSRLITKP 203 Query: 172 LKSLADSTKNIAEGNYSKRVQLQNRDEFGELAQHFNRMADAVERQVTDLSAMAEEKQRMV 231 + +L ST+ I+ G YS+RV+++++DEF L+ HFN MA +E ++ +L EK+ + Sbjct: 204 INTLIGSTQKISLGQYSERVRIKSKDEFNVLSNHFNLMAQTIEDKINELEISNIEKETFI 263 Query: 232 DNLAHELRTPLTSLQGFAQYLNAAHIGEEERMTASGYLWSETLRLKNLVFKLLDLSILSH 291 +NL HEL+TPLTS+ G+A + + EE ++ Y++ E RL+ + FK++DL Sbjct: 264 NNLTHELKTPLTSIIGYANLIRTSKYNEELFFESADYIYKEGKRLEQMAFKMMDLIYAKT 323 Query: 292 QPVERSRIPVVELFESVRRMEQANLDAAGLELILEADIPAVWGDRELLESFLVNCLENSI 351 Q ++ + ++ + V++ ++LI+E + + D++L++ L N +EN+I Sbjct: 324 QEIKLTPEKIMPIIYEVKKSLLVKFKDKNIDLIIEEEDCILDVDKDLIKIALCNLVENAI 383 Query: 352 HASTPGSEIRLAAYEQETAAVLEVTDYGRGMSAGHLERVFEPFYRVDHARSREHGGAGLG 411 AS S+I + + + V D G GM+ HL+++++PFY VD ARSR++ GAG+G Sbjct: 384 KASRNDSKIYIRVFVLNDKIFISVLDSGTGMTKEHLDKIWQPFYVVDKARSRKNNGAGIG 443 Query: 412 LALCRQIAEAHQAQLSLSSEEQKGTTIKLIL 442 L++C++IAE H A + ++SE KGT + +I Sbjct: 444 LSICKKIAEIHNADIKITSELGKGTEVTIIF 474 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.133 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,408,549,541 Number of extensions: 94991018 Number of successful extensions: 381614 Number of sequences better than 1.0e-05: 27916 Number of HSP's gapped: 348370 Number of HSP's successfully gapped: 28163 Length of query: 451 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 312 Effective length of database: 1,751,175,118 Effective search space: 546366636816 Effective search space used: 546366636816 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)