BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0402.0032.p (677 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q8TR39.1 Q8TR39_METAC FmtA-like protein 253 5e-65 B7K7J0.1 B7K7J0_CYAP7 Beta-lactamase 251 2e-64 C0Z8X2.1 C0Z8X2_BREBN Putative uncharacterized protein 232 8e-59 C0GCD0.1 C0GCD0_9FIRM Beta-lactamase 232 1e-58 B8I6Z0.1 B8I6Z0_CLOCE Beta-lactamase 231 2e-58 >Q8TR39.1 Q8TR39_METAC FmtA-like protein Length = 671 Score = 253 bits (646), Expect = 5e-65, Method: Compositional matrix adjust. Identities = 141/329 (42%), Positives = 200/329 (60%), Gaps = 6/329 (1%) Query: 93 HVPGVTLAVVKDGAILLEKGYGYADVEAKVPVDPHKTRFSIASVSKVFTATAALQLAEQG 152 H+PG T+AVVKDG I+ KGYGYAD++ + PV ++T F + SVSK+F TA +QLAEQG Sbjct: 85 HIPGATVAVVKDGQIIFAKGYGYADIDKRQPVVGNQTLFRVGSVSKLFVWTAVMQLAEQG 144 Query: 153 KLNLDADVNRYLPDSLQVANPYKTQLTMKRLLTNTGGFGNAEQREGAWSDTVPEQRVPLE 212 KL+LDADVN YL D QV Y +T+K L+++T GF + G + +PLE Sbjct: 145 KLDLDADVNTYLKD-FQVPATYSKPITLKNLMSHTSGFEDLAI-SGRFFVHNSTDIMPLE 202 Query: 213 QTLQKLLPPLVRAPGDAVQYSNEGFTLAGYIVERASGLSYDEYIRQHIFAPLHMDN-SLT 271 + L+K +P VR PG+ YSN G LA YIVE+ SG+ +D Y+ ++I PL M+N + Sbjct: 203 EYLKKGMPARVRPPGELTAYSNYGSALAAYIVEQVSGMPFDRYVEENILLPLDMNNTTFD 262 Query: 272 YLTPERLHRQLAQGYSYDKGFVKMKQGE-VLTYPAGSIWSTADDMGKFVLAHLQGGGQGE 330 P RL ++ GY Y K E V +PA S+ ST++DM KF++AHLQ G G+ Sbjct: 263 QPLPARLASNMSNGYVYSNNAYTAKPFEYVQVWPASSMSSTSEDMAKFMIAHLQNGRYGD 322 Query: 331 SAILQQDTAKQMHSLQYSAHPLMPGYAYGFFQ-NYKNPAILVHPGDTEAFSSLVSIMPSK 389 ILQ+ TA+QMHS ++ P + G YGF + N +NP ++ H GDT F + ++++P Sbjct: 323 KRILQEATAQQMHSRLFTNAPGVNGVTYGFLEINPENPRVIGHEGDTILFHTQLALIPES 382 Query: 390 GIGFFIGCNSQ-YEGDGGTLRDAFEEQFY 417 +G FI N + E L AF + +Y Sbjct: 383 QLGLFISLNEEDSESAAFELLQAFMDHYY 411 >B7K7J0.1 B7K7J0_CYAP7 Beta-lactamase Length = 669 Score = 251 bits (641), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 139/344 (40%), Positives = 204/344 (59%), Gaps = 12/344 (3%) Query: 81 TDEFMKTA----MDKYHVPGVTLAVVKDGAILLEKGYGYADVEAKVPVDPHKTRFSIASV 136 D+F T M++ ++PG+ +++VKDG I+ KGYGYA+VE K+PV+P KT F +AS+ Sbjct: 62 VDKFFNTIIRRQMEQENIPGLVVSLVKDGEIIFNKGYGYANVEEKIPVEPDKTLFRVASL 121 Query: 137 SKVFTATAALQLAEQGKLNLDADVNRYLPDSLQVANPYKTQLTMKRLLTNTGGFGNAEQR 196 SK+FT TA +QL E+GKLNL DV+RYL D +++ NPY +T L+T TGGF A Sbjct: 122 SKLFTDTAIMQLYEEGKLNLYQDVSRYL-DEVKIKNPYSVPVTAAELMTQTGGFPQALIG 180 Query: 197 EGAWSDTVPEQRVPLEQTLQKLLPPLVRAPGDAVQYSNEGFTLAGYIVERASGLSYDEYI 256 A PEQ PL + L + LPP+ PG+ Y+N G TL GY+V++ SG+ + EY+ Sbjct: 181 LAA---PTPEQMTPLPEYLSEQLPPVTWQPGEIYSYANIGITLLGYLVQKISGIPFVEYV 237 Query: 257 RQHIFAPLHMD-NSLTYLTPERLHRQLAQGYSYDKGFVKMKQGEVLTY-PAGSIWSTADD 314 ++IF PL M+ +S PE L LA GY Y+ K L PA ++ +T D Sbjct: 238 DENIFKPLQMNRSSFRQPLPEELRSDLAVGYQYNGNEYKPVPFLYLNIAPAAAMSTTGTD 297 Query: 315 MGKFVLAHLQGGGQGESAILQQDTAKQMHSLQYSAHPLMPGYAYGFFQNYKNPAILV-HP 373 M F++AHLQ G IL+ DTA MH ++ HPL+PG AYGF + +N + H Sbjct: 298 MAHFMIAHLQLGKYKNQRILKPDTALLMHRQHFTHHPLLPGTAYGFHERLENNIRSIGHY 357 Query: 374 GDTEAFSSLVSIMPSKGIGFFIGCNSQYEGDGGTLRDAFEEQFY 417 G+ ++S ++++P + +G FI NS + G + F + F+ Sbjct: 358 GNLRGYTSSITLLPDQNLGLFIASNS-FNGINENIITQFFDHFF 400 >C0Z8X2.1 C0Z8X2_BREBN Putative uncharacterized protein Length = 667 Score = 232 bits (592), Expect = 8e-59, Method: Compositional matrix adjust. Identities = 127/328 (38%), Positives = 193/328 (58%), Gaps = 9/328 (2%) Query: 79 QLTDEFMKTAMDKYHVPGVTLAVVKDGAILLEKGYGYADVEAKVPVDPHKTRFSIASVSK 138 Q DEF + K ++ G + VVK +L +KGYGYADVE K+PVDP +T F +ASVSK Sbjct: 49 QFADEFFNQSEIKNNMAGASFVVVKGDKVLFKKGYGYADVEKKIPVDPDRTVFRVASVSK 108 Query: 139 VFTATAALQLAEQGKLNLDADVNRYLPDSLQVANPYKTQLTMKRLLTNTGGFGNAEQREG 198 V TATA +QLAEQGK++L+ DV+ Y+ + ++ N T LTMK LLTN+ GF + +G Sbjct: 109 VITATAVMQLAEQGKIDLNKDVSAYMGGA-RIPNKTGTPLTMKHLLTNSTGFDFGDTSDG 167 Query: 199 AWSDTVPEQRVPLEQTLQKLLPPLVRAPGDAVQYSNEGFTLAGYIVERASGLSYDEYIRQ 258 + +D ++ VPL++ + LP ++R PG+ +Y N GF + GY+VE+ +G + EY+++ Sbjct: 168 STTDL--KREVPLKKFVMDNLPNVIRKPGEFYRYDNLGFDIQGYVVEQVAGKPFGEYVQE 225 Query: 259 HIFAPLHMDNSLTYLTPERLHRQLAQGYSYDKGFVKMKQGEVLTYPAGSIWSTADDMGKF 318 IF PL M+NS LT + ++LA Y+ + P G + ST DM KF Sbjct: 226 RIFKPLGMENSDFRLT--SIVKELAVPYNIIGQPIPTYAMVPTELPDGGMLSTGSDMAKF 283 Query: 319 VLAHLQGGGQGESAILQQDTAKQMHSLQYSAHPLMPGYAYGFF----QNYKNPAILVHPG 374 ++AHL G G I++++TA +MH S HP + A GF QNY ++ G Sbjct: 284 MIAHLNKGKLGNETIMEEETAAEMHRPHLSVHPKLNNMALGFEYANQQNYNGQYVIEKAG 343 Query: 375 DTEAFSSLVSIMPSKGIGFFIGCNSQYE 402 D + + + + ++P + +G F+ N YE Sbjct: 344 DLQGYHTGMWLIPEEKVGVFVTVNKDYE 371 >C0GCD0.1 C0GCD0_9FIRM Beta-lactamase Length = 654 Score = 232 bits (591), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 127/322 (39%), Positives = 200/322 (62%), Gaps = 11/322 (3%) Query: 82 DEFMKTAMDKYHVPGVTLAVVKDGAILLEKGYGYADVEAKVPVDPHKTRFSIASVSKVFT 141 D + MD++++P +T++VV +G ILL KGYGYAD E + PVDP K+ F I S +K+FT Sbjct: 44 DTIIGQQMDEFNIPNLTVSVVYNGEILLAKGYGYADYENRKPVDPKKSLFRIGSTAKLFT 103 Query: 142 ATAALQLAEQGKLNLDADVNRYLPDSLQVANPYK------TQLTMKRLLTNTGGFGNAEQ 195 TA +QL EQGKL+LD DVN+YL + YK +T++ L+++T GF + Sbjct: 104 WTAIMQLVEQGKLDLDTDVNQYLDFEIPNVIEYKQGGTEAEPITIRHLMSHTPGFEDYMM 163 Query: 196 REGAWSDTVPEQRVPLEQTLQKLLPPLVRAPGDAVQYSNEGFTLAGYIVERASGLSYDEY 255 + S+ + +PLEQ +++ P V APG+ YSN G +LAGYIVE SG+ + +Y Sbjct: 164 EVFSLSE---DSLIPLEQYVREHRPVRVFAPGEVSAYSNYGVSLAGYIVEAVSGVPFVQY 220 Query: 256 IRQHIFAPLHMD-NSLTYLTPERLHRQLAQGYSYDKGFVKMKQGEVLTYPAGSIWSTADD 314 + ++I+ PL M+ ++ PE L +++ Y Y G + E ++ PAGS+ S+A+D Sbjct: 221 VEENIYQPLGMEYSTFRQPIPESLADNMSKPYRYVDGEFVEAKFEFVSEPAGSMSSSAED 280 Query: 315 MGKFVLAHLQGGGQGESAILQQDTAKQMHSLQYSAHPLMPGYAYGFFQN-YKNPAILVHP 373 M KF+LA+LQGG E++IL+++T M + QY+ HP + G A+GF ++ + N HP Sbjct: 281 MAKFMLAYLQGGQLDEASILKEETVHNMFAEQYTHHPRLDGMAHGFIKSTFNNRETFHHP 340 Query: 374 GDTEAFSSLVSIMPSKGIGFFI 395 G T + + + ++P + +GFFI Sbjct: 341 GGTLLYDTGLFLVPEEDVGFFI 362 >B8I6Z0.1 B8I6Z0_CLOCE Beta-lactamase Length = 662 Score = 231 bits (588), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 134/344 (38%), Positives = 198/344 (57%), Gaps = 19/344 (5%) Query: 79 QLTDEFMKTAMDKYHVPGVTLAVVKDGAILLEKGYGYADVEAKVPVDPHKTRFSIASVSK 138 + D+F K M+K VPG ++VVK+G ILL+KGYGYAD++ KVP++P KT F I S+ K Sbjct: 61 KFCDDFFKKYMEKDSVPGAIISVVKNGQILLKKGYGYADLKNKVPINPDKTAFYICSIGK 120 Query: 139 VFTATAALQLAEQGKL-NLDADVNRYLPDSLQVANPYKTQLTMKRLLTNTGGFGNAEQRE 197 +FT TA +QL E+GK+ +L+ +VN YL ++V N + +T LLT+T G Sbjct: 121 LFTGTAVIQLYEKGKIKDLNDNVNMYLK-KIKVNNKFTNPVTFSNLLTHTSGLDEGSVIG 179 Query: 198 GAWSDTVPEQRVPLEQTLQKLLPPLVRAPGDAVQYSNEGFTLAGYIVERASGLSYDEYIR 257 GA ++ + E L+ L ++R PG +YSN G+ L GY+VE S + + +YI+ Sbjct: 180 GA--SKTKDEILSYEDYLKMKLGSVLREPGSFTRYSNLGYNLLGYLVEGISEMPFRDYIK 237 Query: 258 QHIFAPLHMDNSLTYLTPERLHRQLAQGYSYDKGFVKMKQGEVLTYPA---GSIWSTADD 314 +I PL M NS T + LA Y +D ++ E+ P G I+STADD Sbjct: 238 TNILEPLGMTNS----TAGEIPDNLAIPYIFDGTTMQPSTSEI-NLPGLGEGCIYSTADD 292 Query: 315 MGKFVLAHLQGGGQGESAILQQDTAKQMHSLQYSAHPLMPGYAYGFFQNYKN--PAILVH 372 M KF++AHLQ G E +IL+ +T+K MH+ Q++ +P++PG Y F Q+Y N AI Sbjct: 293 MAKFMIAHLQNGRYKEKSILKAETSKLMHTQQFTNNPVLPGMCYTFMQSYDNNQKAIKHE 352 Query: 373 PGDTEAFSSLVSIMPSKGIGFFIGCNSQYEGDGGTLRDAFEEQF 416 GD + S + ++P IGFF+ N+ TL FE +F Sbjct: 353 GGDASGYISTLYLLPEYNIGFFVEVNTL-----STLPITFESEF 391 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,524,954,219 Number of extensions: 138958752 Number of successful extensions: 314423 Number of sequences better than 1.0e-05: 3273 Number of HSP's gapped: 310017 Number of HSP's successfully gapped: 3292 Length of query: 677 Length of database: 3,060,696,203 Length adjustment: 143 Effective length of query: 534 Effective length of database: 1,713,491,058 Effective search space: 915004224972 Effective search space used: 915004224972 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 135 (56.6 bits)