BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0402.0017.p (310 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B0A7T1.1 B0A7T1_9CLOT Putative uncharacterized protein 388 e-106 Q18CS6.1 Q18CS6_CLOD6 Dihydroorotate dehydrogenase, catalytic su... 386 e-105 B3K3V7.1 B3K3V7_9BACI Dihydroorotate dehydrogenase family protein 385 e-105 B6FW01.1 B6FW01_9CLOT Putative uncharacterized protein 363 1e-98 C1I5K8.1 C1I5K8_9CLOT Dihydroorotate dehydrogenase 1B 362 2e-98 >B0A7T1.1 B0A7T1_9CLOT Putative uncharacterized protein Length = 300 Score = 388 bits (996), Expect = e-106, Method: Compositional matrix adjust. Identities = 186/310 (60%), Positives = 234/310 (75%), Gaps = 10/310 (3%) Query: 1 MINMTANIAGVHFKNPVIMASGTFGFGREYSKLYDVSLLGGISGKGLTLHPKAGNPGVRV 60 M +++ + FKNP+IMASGTFGFGREY+++YD+S LGG+SGKGLTL+ K GN G+RV Sbjct: 1 MADLSVKFKNLTFKNPIIMASGTFGFGREYNEVYDISQLGGVSGKGLTLNAKPGNNGIRV 60 Query: 61 YETASGMLNSVGLENPGVEAFLAKELPYWEMLDTARLVNLGGNTLPDYVLGAELIQRDAD 120 +ET SGM+NSVGLENPGVE F+ KELP++E LD R+ N+GG L DY+ G EL+ D D Sbjct: 61 WETPSGMINSVGLENPGVEGFIEKELPFFEKLDLVRIANIGGGCLEDYIKGVELLN-DKD 119 Query: 121 ARSAAGKPAVDMIELNISCPNVKEGGIAFGVKTPAAQEXXXXXXXXTKLPLAVKLSPNAE 180 +D+IELNISCPNVK GG+AFG+K+ A+E K PL +KLSPNAE Sbjct: 120 ---------IDIIELNISCPNVKAGGMAFGIKSEVAREVVREVRAVCKKPLVIKLSPNAE 170 Query: 181 DIAEMAVMCQEEGADAISLINTISGMKIDVRRRRSVFNNLYAGLSGPAIKPVALRMVHQV 240 DI EMA +C+EEGAD +SL+NT + ID++ R+ VF N+YAGLSGPAIKP+ALRMVH+V Sbjct: 171 DIVEMAKVCEEEGADGVSLVNTFKALAIDIKNRKPVFENVYAGLSGPAIKPIALRMVHEV 230 Query: 241 AKRVSIPVIGMGGITSATDIIEFIMAGATVIQVGTYNFMNLRAGSTLVDELQQFMIEENI 300 K VSIPV GMGGIT+A D IEFIMAGAT +Q+GT NFMN R G +++ + FM +E I Sbjct: 231 CKNVSIPVFGMGGITTAEDAIEFIMAGATCVQIGTANFMNPRVGLEIIEGINDFMEKEGI 290 Query: 301 SSLEEIRGII 310 SL+EIRGII Sbjct: 291 KSLDEIRGII 300 >Q18CS6.1 Q18CS6_CLOD6 Dihydroorotate dehydrogenase, catalytic subunit EC=1.3.3.1 Length = 300 Score = 386 bits (992), Expect = e-105, Method: Compositional matrix adjust. Identities = 189/310 (60%), Positives = 234/310 (75%), Gaps = 10/310 (3%) Query: 1 MINMTANIAGVHFKNPVIMASGTFGFGREYSKLYDVSLLGGISGKGLTLHPKAGNPGVRV 60 M N++ V FKNPVIMASGTFGFG+EY+++YD+ LGGIS KGLTL+ K GN G+RV Sbjct: 1 MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISSKGLTLNKKPGNNGMRV 60 Query: 61 YETASGMLNSVGLENPGVEAFLAKELPYWEMLDTARLVNLGGNTLPDYVLGAELIQRDAD 120 +ET+SGM+NSVGLENPGV+ F+ ELP++ LD R+ N+GG TL DY+LG +++ Sbjct: 61 HETSSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGGGTLEDYLLGVQMLND--- 117 Query: 121 ARSAAGKPAVDMIELNISCPNVKEGGIAFGVKTPAAQEXXXXXXXXTKLPLAVKLSPNAE 180 KP +D+IELNISCPNVK GG+AFG+K A+E TKLPL +KLSPNAE Sbjct: 118 ------KP-IDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLPLVIKLSPNAE 170 Query: 181 DIAEMAVMCQEEGADAISLINTISGMKIDVRRRRSVFNNLYAGLSGPAIKPVALRMVHQV 240 DI MA +C+EEGAD +SL+NT M ID++ RR VF N+YAGLSGPAIKP+ALRMVH+V Sbjct: 171 DIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPAIKPIALRMVHEV 230 Query: 241 AKRVSIPVIGMGGITSATDIIEFIMAGATVIQVGTYNFMNLRAGSTLVDELQQFMIEENI 300 K V+IPV+GMGGIT ATD IEFIMAGAT IQVGT NF+N R G ++D + +FM E I Sbjct: 231 CKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFINPRIGIEIIDGINEFMDREGI 290 Query: 301 SSLEEIRGII 310 SL+EIRGII Sbjct: 291 KSLDEIRGII 300 >B3K3V7.1 B3K3V7_9BACI Dihydroorotate dehydrogenase family protein Length = 310 Score = 385 bits (989), Expect = e-105, Method: Compositional matrix adjust. Identities = 190/310 (61%), Positives = 231/310 (74%) Query: 1 MINMTANIAGVHFKNPVIMASGTFGFGREYSKLYDVSLLGGISGKGLTLHPKAGNPGVRV 60 MI++ +AGV NP++ ASGTFGFG+ Y+ LY + LGGI KGLTL P+ GN G R+ Sbjct: 1 MISIDCELAGVPLSNPILAASGTFGFGKPYADLYPLRKLGGIVSKGLTLTPRLGNTGTRI 60 Query: 61 YETASGMLNSVGLENPGVEAFLAKELPYWEMLDTARLVNLGGNTLPDYVLGAELIQRDAD 120 YET SG++NSVGLENPG+ AFL EL TA +VNLGG T+ +Y GAEL+ + Sbjct: 61 YETPSGIMNSVGLENPGIRAFLEHELSDMTSHGTAVIVNLGGGTVREYAEGAELLTEASS 120 Query: 121 ARSAAGKPAVDMIELNISCPNVKEGGIAFGVKTPAAQEXXXXXXXXTKLPLAVKLSPNAE 180 +AGK AVDMIELNISCPN+KEGG+AFG++ A+E T LPL VKLSP A+ Sbjct: 121 KLRSAGKRAVDMIELNISCPNIKEGGLAFGIENEQAREVVRAVRNATTLPLLVKLSPGAK 180 Query: 181 DIAEMAVMCQEEGADAISLINTISGMKIDVRRRRSVFNNLYAGLSGPAIKPVALRMVHQV 240 D+ EMA MC+ EGAD +SLINTI M ID+R RRSVF+ YAGLSGPAIKP+ALRMVHQV Sbjct: 181 DLREMARMCEAEGADGLSLINTIQAMAIDIRERRSVFDRAYAGLSGPAIKPIALRMVHQV 240 Query: 241 AKRVSIPVIGMGGITSATDIIEFIMAGATVIQVGTYNFMNLRAGSTLVDELQQFMIEENI 300 A+ VSIPV+G+GGI SA DI+EFIMAGA +Q+GTYNF+NLRAG TL +EL Q M E I Sbjct: 241 ARSVSIPVVGIGGICSAEDILEFIMAGAAAVQIGTYNFINLRAGDTLAEELIQLMENEGI 300 Query: 301 SSLEEIRGII 310 SL++IRGII Sbjct: 301 QSLDDIRGII 310 >B6FW01.1 B6FW01_9CLOT Putative uncharacterized protein Length = 300 Score = 363 bits (931), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 174/310 (56%), Positives = 230/310 (74%), Gaps = 10/310 (3%) Query: 1 MINMTANIAGVHFKNPVIMASGTFGFGREYSKLYDVSLLGGISGKGLTLHPKAGNPGVRV 60 M ++ + FKNP++MASGTFGFG+EY++ YD++ LGG+S KGLTL+ K GN G+R+ Sbjct: 1 MADLRVKFGEIEFKNPIVMASGTFGFGKEYNEYYDINELGGVSSKGLTLNAKPGNNGLRI 60 Query: 61 YETASGMLNSVGLENPGVEAFLAKELPYWEMLDTARLVNLGGNTLPDYVLGAELIQRDAD 120 +ET SG++NSVGLENPGV+ F+ E+P++ L+ R+ N+GG L DYV G EL+ D D Sbjct: 61 HETPSGIMNSVGLENPGVQGFIDHEMPFFGNLNCVRIANVGGGCLEDYVKGVELLN-DQD 119 Query: 121 ARSAAGKPAVDMIELNISCPNVKEGGIAFGVKTPAAQEXXXXXXXXTKLPLAVKLSPNAE 180 +DM+ELNISCPNVK GG+AFG+K A+E K PL VKLSPNAE Sbjct: 120 ---------IDMVELNISCPNVKAGGMAFGIKNEVAREVVREVRKVCKHPLVVKLSPNAE 170 Query: 181 DIAEMAVMCQEEGADAISLINTISGMKIDVRRRRSVFNNLYAGLSGPAIKPVALRMVHQV 240 DI MA +C+EEGAD +SL+NT + ID++RR+ VF N+ AGLSGPAIKP+ALRMV++V Sbjct: 171 DIVGMAKVCEEEGADGVSLVNTFKALAIDIKRRKPVFENVTAGLSGPAIKPIALRMVYEV 230 Query: 241 AKRVSIPVIGMGGITSATDIIEFIMAGATVIQVGTYNFMNLRAGSTLVDELQQFMIEENI 300 +K V+IPVIG+GGI++A D+IEFIMAGATV+QVGT NFM+ G+ ++ +L FM E I Sbjct: 231 SKAVNIPVIGIGGISTAEDVIEFIMAGATVVQVGTANFMDPEIGTKIIKDLNDFMDREGI 290 Query: 301 SSLEEIRGII 310 SL+EIRGII Sbjct: 291 KSLDEIRGII 300 >C1I5K8.1 C1I5K8_9CLOT Dihydroorotate dehydrogenase 1B Length = 299 Score = 362 bits (929), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 179/309 (57%), Positives = 226/309 (73%), Gaps = 14/309 (4%) Query: 4 MTANIAGVHFKNPVIMASGTFGFGREYSKLYDVSLLGGISGKGLTLHPKAGNPGVRVYET 63 + NI G+ FKNPVI ASGTFGFG EY+ YDV +LGGIS KGLTL+PK GN G+RVYET Sbjct: 2 LKVNINGIEFKNPVIAASGTFGFGAEYNNFYDVGILGGISSKGLTLNPKGGNEGIRVYET 61 Query: 64 ASGMLNSVGLENPGVEAFLAKELPYWEMLDTARLVNLGGNTLPDYVLGAELIQ--RDADA 121 SGM+NSVGL+NPG++ F+ +ELP + L T + N+GG + DY E IQ RD D Sbjct: 62 PSGMMNSVGLQNPGIDRFIKEELPKMKELGTNIIANVGGGCIEDY---EEAIQKLRDTD- 117 Query: 122 RSAAGKPAVDMIELNISCPNVKEGGIAFGVKTPAAQEXXXXXXXXTKLPLAVKLSPNAED 181 +DMIELNISCPNVK GG+AFG+K+ A E + PL VKLSPNAED Sbjct: 118 --------IDMIELNISCPNVKSGGMAFGIKSNVAYEVVSKIKKISDKPLMVKLSPNAED 169 Query: 182 IAEMAVMCQEEGADAISLINTISGMKIDVRRRRSVFNNLYAGLSGPAIKPVALRMVHQVA 241 I MAV C+E GAD+ISLINT+ G ID +R+ +FNN+YAGLSGPA+KP+ALRMVH+V+ Sbjct: 170 IVRMAVSCEEAGADSISLINTLKGFAIDPYKRKPIFNNIYAGLSGPAVKPIALRMVHEVS 229 Query: 242 KRVSIPVIGMGGITSATDIIEFIMAGATVIQVGTYNFMNLRAGSTLVDELQQFMIEENIS 301 K VSIPVIG+GGI++ D IEF+MAGAT IQ+GT NF+N AG ++DE+++F IE+ I Sbjct: 230 KAVSIPVIGLGGISNGIDAIEFMMAGATAIQIGTVNFINPMAGKEIIDEMEKFCIEQGIK 289 Query: 302 SLEEIRGII 310 +++I G I Sbjct: 290 DIKDIIGCI 298 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.136 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,736,113,768 Number of extensions: 71332648 Number of successful extensions: 188080 Number of sequences better than 1.0e-05: 1407 Number of HSP's gapped: 186044 Number of HSP's successfully gapped: 1408 Length of query: 310 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 175 Effective length of database: 1,788,859,178 Effective search space: 313050356150 Effective search space used: 313050356150 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)