BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0397.0002.p (418 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KGN6.1 B3KGN6_9BACI Major facilitator superfamily MFS_1 477 e-133 C5CHJ2.1 C5CHJ2_9THEM Major facilitator superfamily MFS_1 311 9e-83 A1S0L4.1 A1S0L4_THEPD Major facilitator superfamily MFS_1 254 1e-65 B6YSZ7.1 B6YSZ7_THEON Hypothetical permease 253 2e-65 Q5JGZ1.1 Q5JGZ1_PYRKO Predicted permease, major facilitator supe... 253 3e-65 >B3KGN6.1 B3KGN6_9BACI Major facilitator superfamily MFS_1 Length = 402 Score = 477 bits (1228), Expect = e-133, Method: Compositional matrix adjust. Identities = 245/418 (58%), Positives = 293/418 (70%), Gaps = 24/418 (5%) Query: 1 VKKVWLLGFGFFSISITWSLYNAFVPFFLEKYVHSVALISFMMTIDNYFALFLQPWIGNR 60 ++K WLLGFGFFSISITW+LYNAFVP+FLE Y+ SVA I F MTIDNYFALFLQPWIG+R Sbjct: 1 MRKTWLLGFGFFSISITWALYNAFVPYFLEDYISSVAWIGFFMTIDNYFALFLQPWIGSR 60 Query: 61 SDRTATRFGRRMPYLMIGMPLAAVLTMLIPFHSGXXXXXXXXXXXXXXXXXYRSPTVALM 120 SDRT TR+GRRMPYL+IGMPL A+ T +IPFH+G YRSPTV+LM Sbjct: 61 SDRTHTRYGRRMPYLLIGMPLGALFTAMIPFHNGMATLLLFMVLMNLAMSLYRSPTVSLM 120 Query: 121 PDITPEHQRTKANGLINFMGGAGSILAFGAGSYLYDSSPVLPFVAAGLITLLCLFIVSRF 180 PDIT E +RT+ANG+INFMGG GSILAFG GS LY + LPF+AA +TL+ LFI+ F Sbjct: 121 PDITEEKRRTRANGIINFMGGLGSILAFGVGSVLYSAHASLPFIAAAGVTLVSLFILKTF 180 Query: 181 IKEGRDGVNTXXXXXXXXXXXXXXLQPGELVLPLSRPARVSLKKQLDRTTVWLLAAIFFW 240 I+E RD PG +R A++S K Q++RTTV LLAAIFFW Sbjct: 181 IQEKRDA-------------------PGYQAQTAAR-AKISFKSQINRTTVLLLAAIFFW 220 Query: 241 FVAYQGVETLFTLYGKHHLGLSEQXXXXXXXXXXXXXVIFAIPSGWLGGRFGKKPVIILG 300 FVAYQGVETLFTLYGK+ +GL+E V+FAIPSGWLGG+FGKK +I++G Sbjct: 221 FVAYQGVETLFTLYGKNEMGLTESQASFSLTFFSLAFVLFAIPSGWLGGKFGKKRLILIG 280 Query: 301 VCGLMAVFALVGFAENVXXXXXXXXXXXIFWACININSYPFVVAKRNEESIGTRTGIYYL 360 V GL+ VFALV + E++ +FWACININSYPF+V+ E+SIGTRTG+YYL Sbjct: 281 VSGLLIVFALVPWVESLLLLRVLLTVGGLFWACININSYPFIVSTGTEDSIGTRTGMYYL 340 Query: 361 VSSLAAITSPPLLGLLIDLTDYSTLFYAATASMAFALVCLLLMKGRARAVNTVHSNKA 418 VSSLAAI+SPPLLG LID YS LFY A SM AL+C+L++ R T HS KA Sbjct: 341 VSSLAAISSPPLLGKLIDGMGYSILFYCAAGSMLLALICMLMI----RHQETDHSAKA 394 >C5CHJ2.1 C5CHJ2_9THEM Major facilitator superfamily MFS_1 Length = 409 Score = 311 bits (796), Expect = 9e-83, Method: Compositional matrix adjust. Identities = 171/417 (41%), Positives = 234/417 (56%), Gaps = 27/417 (6%) Query: 2 KKVWLLGFGFFSISITWSLYNAFVPFFLEKYVHSVALISFMMTIDNYFALFLQPWIGNRS 61 KK ++LG GFF+IS+TW LYN ++P FL+ Y+ S I+ +MT+DN A+ L P G+ S Sbjct: 6 KKTFILGLGFFAISLTWPLYNYYIPLFLKTYIKSQFWINSIMTLDNILAITLIPVFGSLS 65 Query: 62 DRTATRFGRRMPYLMIGMPLAAVLTMLIPFHSGXXXXXXXXXXXXXXXXXYRSPTVALMP 121 DRT TRFGRRMPYL+IG+P++A+L L+P +S YR+PTVALMP Sbjct: 66 DRTNTRFGRRMPYLLIGIPISAILFALLPQYSSFTSLMIILISFNLAMAIYRAPTVALMP 125 Query: 122 DITPEHQRTKANGLINFMGGAGSILAFGAGSYLYDSSPVLPFVAAGLITLLCLFIVSRFI 181 DITP R+KANG+INFMGG S+L G+ LYD + LPF+A ++ L L ++ FI Sbjct: 126 DITPRPLRSKANGIINFMGGLASVLVLSVGAVLYDINKNLPFIATAILMFLALAMLYIFI 185 Query: 182 KEGRDGVNTXXXXXXXXXXXXXXLQPGELVLPLSRPARVSLKKQLDRTTVWLLAAIFFWF 241 KE ++ T + + +S + + K D+T +++L AIFFWF Sbjct: 186 KEPKNITVTT--------------NEEQKIGLISSIKEIFVSK--DKTALYILLAIFFWF 229 Query: 242 VAYQGVETLFTLYGKHHLGLSEQXXXXXXXXXXXXXVIFAIPSGWLGGRFGKKPVIILGV 301 V YQGVE F+ Y H L + E ++FAIPSG++ +FGKK I++GV Sbjct: 230 VGYQGVEATFSNYSVHFLKIKESTGSIILSSFAAAFLVFAIPSGFIATKFGKKRTILVGV 289 Query: 302 CGLMAVFALV----------GFAENVXXXXXXXXXXXIFWACININSYPFVVAKRNEESI 351 GL VF L+ G NV FWACININSYP VV EE + Sbjct: 290 AGLFIVFGLLAIVRTTTSVFGMPYNVVMMLLFAIGG-FFWACININSYPMVVETTTEEKV 348 Query: 352 GTRTGIYYLVSSLAAITSPPLLGLLIDLTDYSTLFYAATASMAFALVCLLLMKGRAR 408 GT TGIYY SSLAAI P + G +D + ++F A S A A + + ++K + Sbjct: 349 GTYTGIYYFFSSLAAILGPLIFGFFVDFLGFGSMFITAAVSFAIAFIFVFMIKSDTK 405 >A1S0L4.1 A1S0L4_THEPD Major facilitator superfamily MFS_1 Length = 421 Score = 254 bits (649), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 160/422 (37%), Positives = 231/422 (54%), Gaps = 27/422 (6%) Query: 3 KVWLLGFGFFSISITWSLYNAFVPFFLEKYVHSVALISFMMTIDNYFALFLQPWIGNRSD 62 K++LLGFGFF ISI WS+YN++VP FL+++ + L+ F+MTIDN FA+ L P+IG SD Sbjct: 8 KIFLLGFGFFGISILWSIYNSYVPIFLKEFGLASWLVGFIMTIDNIFAVVLLPYIGVLSD 67 Query: 63 RTATRFGRRMPYLMIGMPLAAVLTMLIPFHSGX-XXXXXXXXXXXXXXXXYRSPTVALMP 121 T TR GRR PY+++G P AA+ LIP G +RSP +A MP Sbjct: 68 VTRTRIGRRKPYIILGAPPAALTFALIPLLRGDFYAMLAVIVVMNFSMALFRSPVIAFMP 127 Query: 122 DITPEHQRTKANGLINFMGGAGSILAFGAGSYLYDSSPVLPFVAAGLITLLCLFIVSRFI 181 DITP +R++ANG+INFMGG GS+LAF G+ LY+ +P PFVAA + LL +V + Sbjct: 128 DITPSEKRSQANGIINFMGGVGSLLAFFVGAKLYEMNPSYPFVAAAVTMLLASLLVVLLV 187 Query: 182 KEGRDGVNTXXXXXXXXXXXXXXLQPGELVLPLSRPARVSLKKQL-------DRTTVWLL 234 E + ++ GEL+ R + L L D++ +++L Sbjct: 188 DEPEE-----------FKARGGSVRLGELLRESFRKSFSELSANLREAFLGEDKSLLFML 236 Query: 235 AAIFFWFVAYQGVETLFTLYGKHHLGLSEQXXXXXXXXXXXXXVIFAIPSGWLGGRFGKK 294 A+IF WF+ Y +ET FT Y K +LG+ E ++F++P+G++G R G++ Sbjct: 237 ASIFLWFIGYNAIETFFTSYAKWYLGIGEAAGSLILGFVALGFLVFSLPAGFIGARLGRR 296 Query: 295 PVIILGVCGLMAVFALVGFAEN-VXXXXXXXXXXXIF------WACININSYPFVVAKRN 347 + LG+ L+ + L +A V IF WA +N+NS P VV + Sbjct: 297 KTMTLGLALLVVLLGLAFYASTAVKTGAVIYVLGAIFFFGGFAWALVNVNSLPTVVDMTS 356 Query: 348 EESIGTRTGIYYLVSSLAAITSPPLLGLLIDLTDYSTLF-YAATASMAFALVCLLLMKGR 406 E +G TG+YY S AAIT+PPL GL ID+ Y LF Y+ +A A+ + +G Sbjct: 357 RERLGAYTGLYYFASQSAAITAPPLAGLFIDVLGYQALFPYSIVFLLASAVTLQFVKRGE 416 Query: 407 AR 408 AR Sbjct: 417 AR 418 >B6YSZ7.1 B6YSZ7_THEON Hypothetical permease Length = 441 Score = 253 bits (647), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 154/424 (36%), Positives = 220/424 (51%), Gaps = 29/424 (6%) Query: 2 KKVWLLGFGFFSISITWSLYNAFVPFFLEKYVH-SVALISFMMTIDNYFALFLQPWIGNR 60 ++++LGFGFF ISI W+LYNA+VP FL+ H S + F+MTIDN FA+ L P++G Sbjct: 7 SRIFILGFGFFGISIIWALYNAYVPIFLQDTFHLSKTVTGFIMTIDNLFAVLLLPFLGAL 66 Query: 61 SDRTATRFGRRMPYLMIGMPLAAVLTMLIPF---HSGXXXXXXXXXXXXXXXXXYRSPTV 117 SD T T+ GRR PY+++G P AA++ LIP + +RSP + Sbjct: 67 SDMTRTKLGRRKPYILLGAPSAALMFALIPVAREYESLALFMGTIIFMNFFMALFRSPVI 126 Query: 118 ALMPDITPEHQRTKANGLINFMGGAGSILAFGAGSYLYDSSPVLPFVAAGLITLLCLFIV 177 A MPDITP +R++ANG+INFMGG G++LA+ G LYD + PF I LL +V Sbjct: 127 AFMPDITPSEKRSQANGIINFMGGLGALLAYFGGKALYDMNYAYPFYLGAAIMLLANLLV 186 Query: 178 SRFIKEGRD-GVNTXXXXXXXXXXXXXXLQPGELVLPLSRPARVSLKKQL---DRTTVWL 233 F+ E + V GEL + +LK +R+ + Sbjct: 187 VLFVPEPEEYRVPGKKLELKKLLKETTRKSSGEL--------KENLKDVFASKERSLFAI 238 Query: 234 LAAIFFWFVAYQGVETLFTLYGKHHLGLSEQXXXXXXXXXXXXXVIFAIPSGWLGGRFGK 293 L AIFFWF+A+ +ET FT Y K+HL + E +IFAIP+G++GGRFG+ Sbjct: 239 LVAIFFWFIAFNSLETFFTSYAKYHLRIDESTGAFMLGVFSLSFMIFAIPAGFMGGRFGR 298 Query: 294 KPVIILGVCGLMAVFALV-GFAEN------------VXXXXXXXXXXXIFWACININSYP 340 K I LG+ ++A+ L E+ V I WA +N+NS P Sbjct: 299 KRTITLGLLIVVAIMLLAYQLGESSKPASSSLNDPVVMSFMGLFFVGGIGWAMVNVNSLP 358 Query: 341 FVVAKRNEESIGTRTGIYYLVSSLAAITSPPLLGLLIDLTDYSTLFYAATASMAFALVCL 400 VV EE +G TG+YY S A + +PPL G+ ID+ Y TL AT +++ + Sbjct: 359 MVVDMTTEEKLGGYTGLYYFFSQAANLVAPPLSGVFIDVAGYKTLLPFATLFFILSMIAM 418 Query: 401 LLMK 404 ++ Sbjct: 419 QFVR 422 >Q5JGZ1.1 Q5JGZ1_PYRKO Predicted permease, major facilitator superfamily Length = 454 Score = 253 bits (645), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 161/440 (36%), Positives = 223/440 (50%), Gaps = 51/440 (11%) Query: 2 KKVWLLGFGFFSISITWSLYNAFVPFFLEKYVH-SVALISFMMTIDNYFALFLQPWIGNR 60 +++LLGFGFF ISI W+LYNA++P FL+ H + + F+MTIDN FA+ L P++G Sbjct: 7 SRIFLLGFGFFGISIIWALYNAYIPLFLQDTFHMNRTITGFIMTIDNLFAVLLLPFLGAL 66 Query: 61 SDRTATRFGRRMPYLMIGMPLAAVLTMLIPF---HSGXXXXXXXXXXXXXXXXXYRSPTV 117 SD T TR GRR PY+++G P AA++ LIP H +RSP V Sbjct: 67 SDMTRTRLGRRKPYILLGAPSAALMFALIPVAREHGNLALFMGTIIFMNFFMALFRSPVV 126 Query: 118 ALMPDITPEHQRTKANGLINFMGGAGSILAFGAGSYLYDSSPVLPFVAAGLITLLCLFIV 177 A MPDITP +R++ANG+INFMGG G++LA+ G LYD S PF A LI LL +V Sbjct: 127 AFMPDITPSEKRSQANGIINFMGGLGALLAYFGGKVLYDMSYAYPFYAGALIMLLANLLV 186 Query: 178 SRFIKEGRDGVNTXXXXXXXXXXXXXXLQPGELVLPLSRPARVSLKKQL-------DRTT 230 F+ E + + EL+ SR + LK+ L +R+ Sbjct: 187 VLFVPEPEE-----------YRVPGKKINLRELLSETSRKSFGELKENLKDVFASHERSL 235 Query: 231 VWLLAAIFFWFVAYQGVETLFTLYGKHHL-GLS------------EQXXXXXXXXXXXXX 277 + +L AIFFWF+A+ +ET FT Y K+HL G+ E Sbjct: 236 LAILLAIFFWFIAFNSLETFFTSYVKYHLYGIPVGAAETEITRKIESTGAFMLGMFSLSF 295 Query: 278 VIFAIPSGWLGGRFGKKPVIILGVCGLMAVFALVGFAENVXXXXXXXXXXXIF------- 330 +IFAIP+G+LG R G++ I LG+ ++A+ F + Sbjct: 296 MIFAIPAGFLGARIGRRKTITLGLLTIIAIILAAFFIGETSKPQEVALTDPVIMKFMGLF 355 Query: 331 ------WACININSYPFVVAKRNEESIGTRTGIYYLVSSLAAITSPPLLGLLIDLTDYST 384 WA IN+NS P VV +E +G TG+YY S A + +PP G L+DL Y T Sbjct: 356 FVGGIGWAMINVNSLPMVVDMTVDEKVGGYTGLYYFFSQAANLVAPPFAGALLDLIGYET 415 Query: 385 LFYAATASMAFALVCLLLMK 404 L A MAF L+ L+ M+ Sbjct: 416 LLPFA---MAFFLLALIAMQ 432 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.328 0.142 0.442 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,108,733,605 Number of extensions: 74702177 Number of successful extensions: 277519 Number of sequences better than 1.0e-05: 154 Number of HSP's gapped: 277620 Number of HSP's successfully gapped: 164 Length of query: 418 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 280 Effective length of database: 1,760,596,133 Effective search space: 492966917240 Effective search space used: 492966917240 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.8 bits) S2: 132 (55.5 bits)