BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0394.0002.p (397 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q894W4.1 Q894W4_CLOTE Sensor protein EC=2.7.13.3 319 3e-85 B1KWY4.1 B1KWY4_CLOBM Sensor protein EC=2.7.13.3 259 3e-67 A7FS44.1 A7FS44_CLOB1 Sensor protein EC=2.7.13.3 257 2e-66 A5HZY0.1 A5HZY0_CLOBH Sensor protein EC=2.7.13.3 257 2e-66 B1Q6Q9.1 B1Q6Q9_CLOBO Sensor protein EC=2.7.13.3 256 4e-66 >Q894W4.1 Q894W4_CLOTE Sensor protein EC=2.7.13.3 Length = 417 Score = 319 bits (817), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 166/388 (42%), Positives = 237/388 (61%), Gaps = 3/388 (0%) Query: 6 MFFFMNYQVSQINKAVVNQNAALIGYVLKQAPQLENEIIHFITQGAQEDEIVAGKRSLAQ 65 ++FF N+Q ++N+ +VNQN+ +IG VL P+LEN II ++T+ A +++I+ GK L Q Sbjct: 28 IYFFFNHQFHKLNENIVNQNSMIIGKVLYDHPELENNIIKYVTKEATKEQIIKGKEILKQ 87 Query: 66 YAYTEDMLVNDQPILSD--NALPFKTAAQVXXXXXXXXXXXGWEYRKIFDKIRAITFAAE 123 Y Y EDM + QP+L + K EY+ IF K++ I+ A+E Sbjct: 88 YGYYEDMKITSQPLLKSFYESFQVKFILAFILGLIPLIGIVLLEYKNIFKKVKEISHASE 147 Query: 124 QVVEHQFDQPLPENDEGDFGTLGRNFNAMAERLHNSLRQLQQEKTFLRNLLSDISHQLKT 183 +V+E + L E+ EGDF L NFN M+ L SL +L+++K FL+N++SDISHQLKT Sbjct: 148 KVIEGDYSLILREDREGDFAILAHNFNLMSNILKLSLHKLKEDKIFLKNIISDISHQLKT 207 Query: 184 PLAALIVFNENLLNDPHMKEEMRTKFLDRSRLQLERMEWLIISLLKLARVEAGAITFQKE 243 PL +L+ NE LL MK+++R FL +S QL RMEWLIISLLK+AR+EA AI F+K Sbjct: 208 PLTSLLTINELLLTRKEMKDDVRIDFLQKSGSQLNRMEWLIISLLKIARLEAQAINFEKR 267 Query: 244 RVRVREMIDHAVHSLRMLSEQRKQQIHIHGG-EAMYVWADEEWLTEAIINLIKNALEHTP 302 I A+ SL+ S+ + Q+I + G + +Y + DE+W EAI+N+IKN +EHT Sbjct: 268 NTLGINFIQDALSSLKFKSDAKHQKIMVSGNLDNVYFYVDEQWTIEAILNIIKNCIEHTK 327 Query: 303 LEGAIDVILEENSVFQTVIIRDRGEGISSEDLPHIFERFYSGRSTEKPQXXXXXXXXXXX 362 G I V + E +F ++I D GEGI +DLPHIFERFY G ++ + Sbjct: 328 EGGEIKVHISETPLFSRILIEDNGEGIDKKDLPHIFERFYKGSNSVNAESVGIGLALTKV 387 Query: 363 XXEEQGGMITVVSQLGIGTEFRISFNKG 390 E QGG I V S+ GIG++F I+F KG Sbjct: 388 IIERQGGTILVNSKKGIGSKFTITFLKG 415 >B1KWY4.1 B1KWY4_CLOBM Sensor protein EC=2.7.13.3 Length = 420 Score = 259 bits (662), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 148/396 (37%), Positives = 225/396 (56%), Gaps = 8/396 (2%) Query: 1 MLALLMFFFMNYQVSQINKAVVNQNAALIGYVLKQAPQLENEIIHFITQGA-----QEDE 55 + A+L + +++++NK +NQN ++G +L + P+LE+E+I + +E Sbjct: 23 LFAILTTILIKGELNKLNKDYINQNTLIVGNILSKHPELEDEVILSLNSNKDARYNEEKN 82 Query: 56 IVAGKRSLAQYAYTEDMLVNDQPILSDNALPF--KTAAQVXXXXXXXXXXXGWEYRKIFD 113 GK+ L +Y+Y E++ + P+L + ++ F +T +++ + Sbjct: 83 YKIGKKVLEKYSYDENLDIYKNPVLKNFSINFIYRTIIYFGVAIIIIYIIIYDKFKYFYK 142 Query: 114 KIRAITFAAEQVVEHQFDQPLPENDEGDFGTLGRNFNAMAERLHNSLRQLQQEKTFLRNL 173 K T A+E ++E F + + EN EGDF L FN M+ RL SL L++EK FL+N+ Sbjct: 143 KAEIFTEASEDIMEGHFSKFIDENKEGDFYILSSKFNLMSNRLEESLLSLKKEKIFLKNI 202 Query: 174 LSDISHQLKTPLAALIVFNENLLNDPHMKEEMRTKFLDRSRLQLERMEWLIISLLKLARV 233 +SDISHQLKTPL++LI+FNE L+ D M E R FL S QL RMEWLII+LLK+ R+ Sbjct: 203 ISDISHQLKTPLSSLIMFNE-LMKDESMPIEDRENFLKLSDEQLRRMEWLIINLLKIGRL 261 Query: 234 EAGAITFQKERVRVREMIDHAVHSLRMLSEQRKQQIHIHGGEAMYVWADEEWLTEAIINL 293 EAG I F++E + ++ A+ L ++++ QQ+ I+ E +Y D EW EAI N+ Sbjct: 262 EAGVIEFKRENNPLYVTVNKALAGLSEKAKEKSQQVIINIDEDVYFKHDMEWTAEAISNI 321 Query: 294 IKNALEHTPLEGAIDVILEENSVFQTVIIRDRGEGISSEDLPHIFERFYSGRSTEKPQXX 353 IKN++EHT G I + EE + T+ I+D GEGI + IFERFY G ++ P Sbjct: 322 IKNSIEHTDNYGQIKISCEETPISLTISIKDNGEGIPEKLQNKIFERFYKGENSVNPSSI 381 Query: 354 XXXXXXXXXXXEEQGGMITVVSQLGIGTEFRISFNK 389 E Q G ITV S++G GTEF I+F K Sbjct: 382 GIGLSLTKSIIESQNGSITVESEMGEGTEFIITFLK 417 >A7FS44.1 A7FS44_CLOB1 Sensor protein EC=2.7.13.3 Length = 420 Score = 257 bits (656), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 146/396 (36%), Positives = 227/396 (57%), Gaps = 12/396 (3%) Query: 1 MLALLMFFFMNYQVSQINKAVVNQNAALIGYVLKQAPQLENEIIHFITQGAQEDEIV--- 57 + A L F+ +++++NK +NQN ++G +L + P+LE EII ++ + ED I Sbjct: 23 LFATLTTIFIKGELNKLNKDYINQNTLIVGNILSKHPELEEEII--LSLKSNEDAIYNEE 80 Query: 58 ----AGKRSLAQYAYTEDMLVNDQPILSDNALPF--KTAAQVXXXXXXXXXXXGWEYRKI 111 GK L +Y+Y E++ + P+L + ++ F +T +++ Sbjct: 81 KNYKIGKNILEKYSYDENLDIYKNPVLKNFSINFIYRTIIYFGVAIIIIYIIIYDKFKYF 140 Query: 112 FDKIRAITFAAEQVVEHQFDQPLPENDEGDFGTLGRNFNAMAERLHNSLRQLQQEKTFLR 171 + K T A+E++++ F++ + EN EGDF L FN M+ RL SL L++EK FL+ Sbjct: 141 YKKAEVFTKASEEIMDGHFNKFVDENREGDFYVLSSKFNLMSNRLEESLLNLKKEKIFLK 200 Query: 172 NLLSDISHQLKTPLAALIVFNENLLNDPHMKEEMRTKFLDRSRLQLERMEWLIISLLKLA 231 N++SDISHQLKTPL++LI+FNE L+ D +M E R FL S QL RMEWLII+LLK+ Sbjct: 201 NIISDISHQLKTPLSSLIMFNE-LMKDENMPMEDRKNFLKLSDEQLRRMEWLIINLLKIG 259 Query: 232 RVEAGAITFQKERVRVREMIDHAVHSLRMLSEQRKQQIHIHGGEAMYVWADEEWLTEAII 291 R+EAG + F++E + ++ A+ L ++++ QQ+ ++ E +Y D +W EAI Sbjct: 260 RLEAGVVEFRRENNPLYVTVNKALAGLSEKAKEKSQQVIVNIDEDVYFKHDMDWTAEAIS 319 Query: 292 NLIKNALEHTPLEGAIDVILEENSVFQTVIIRDRGEGISSEDLPHIFERFYSGRSTEKPQ 351 N+IKN++EHT G I + EE + T+ I+D GEGI + IFERFY G ++ P Sbjct: 320 NIIKNSIEHTDNYGQIKISCEETPISLTISIKDNGEGIPEKLQNKIFERFYKGENSVNPS 379 Query: 352 XXXXXXXXXXXXXEEQGGMITVVSQLGIGTEFRISF 387 E Q G I V S++G GTEF I+F Sbjct: 380 SIGIGLSLTKSIIESQNGSIIVESEMGEGTEFIITF 415 >A5HZY0.1 A5HZY0_CLOBH Sensor protein EC=2.7.13.3 Length = 420 Score = 257 bits (656), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 146/396 (36%), Positives = 227/396 (57%), Gaps = 12/396 (3%) Query: 1 MLALLMFFFMNYQVSQINKAVVNQNAALIGYVLKQAPQLENEIIHFITQGAQEDEIV--- 57 + A L F+ +++++NK +NQN ++G +L + P+LE EII ++ + ED I Sbjct: 23 LFATLTTIFIKGELNKLNKDYINQNTLIVGNILSKHPELEEEII--LSLKSNEDAIYNEE 80 Query: 58 ----AGKRSLAQYAYTEDMLVNDQPILSDNALPF--KTAAQVXXXXXXXXXXXGWEYRKI 111 GK L +Y+Y E++ + P+L + ++ F +T +++ Sbjct: 81 KNYKIGKNILEKYSYDENLDIYKNPVLKNFSINFIYRTIIYFGVAIIIIYIIIYDKFKYF 140 Query: 112 FDKIRAITFAAEQVVEHQFDQPLPENDEGDFGTLGRNFNAMAERLHNSLRQLQQEKTFLR 171 + K T A+E++++ F++ + EN EGDF L FN M+ RL SL L++EK FL+ Sbjct: 141 YKKAEVFTKASEEIMDGHFNKFVDENREGDFYVLSSKFNLMSNRLEESLLNLKKEKIFLK 200 Query: 172 NLLSDISHQLKTPLAALIVFNENLLNDPHMKEEMRTKFLDRSRLQLERMEWLIISLLKLA 231 N++SDISHQLKTPL++LI+FNE L+ D +M E R FL S QL RMEWLII+LLK+ Sbjct: 201 NIISDISHQLKTPLSSLIMFNE-LMKDENMPMEDRKNFLKLSDEQLRRMEWLIINLLKIG 259 Query: 232 RVEAGAITFQKERVRVREMIDHAVHSLRMLSEQRKQQIHIHGGEAMYVWADEEWLTEAII 291 R+EAG + F++E + ++ A+ L ++++ QQ+ ++ E +Y D +W EAI Sbjct: 260 RLEAGVVEFRRENNPLYVTVNKALAGLSEKAKEKSQQVIVNIDEDVYFKHDMDWTAEAIS 319 Query: 292 NLIKNALEHTPLEGAIDVILEENSVFQTVIIRDRGEGISSEDLPHIFERFYSGRSTEKPQ 351 N+IKN++EHT G I + EE + T+ I+D GEGI + IFERFY G ++ P Sbjct: 320 NIIKNSIEHTDNYGQIKISCEETPISLTISIKDNGEGIPEKLQNKIFERFYKGENSVNPS 379 Query: 352 XXXXXXXXXXXXXEEQGGMITVVSQLGIGTEFRISF 387 E Q G I V S++G GTEF I+F Sbjct: 380 SIGIGLSLTKSIIESQNGSIIVESEMGEGTEFIITF 415 >B1Q6Q9.1 B1Q6Q9_CLOBO Sensor protein EC=2.7.13.3 Length = 420 Score = 256 bits (653), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 145/396 (36%), Positives = 226/396 (57%), Gaps = 8/396 (2%) Query: 1 MLALLMFFFMNYQVSQINKAVVNQNAALIGYVLKQAPQLENEIIHFITQGA-----QEDE 55 + A+L F+ +++++NK +NQNA ++G +L + P+LE+E+I + QE Sbjct: 23 LFAILTTIFIKGELNKLNKDYINQNALIVGNILSKHPELEDEVILSLNSNKDARYNQEKN 82 Query: 56 IVAGKRSLAQYAYTEDMLVNDQPILSDNALPF--KTAAQVXXXXXXXXXXXGWEYRKIFD 113 GK+ L +Y+Y E++ + PIL++ ++ F + +++ + Sbjct: 83 YKIGKKVLEKYSYDENLDIYKNPILNNFSMNFIYRIIIYFALAIFIIYIIIYDKFKYFYK 142 Query: 114 KIRAITFAAEQVVEHQFDQPLPENDEGDFGTLGRNFNAMAERLHNSLRQLQQEKTFLRNL 173 K T A+E ++E F + + EN EG+F L FN M+ RL SL L++EK FL+N+ Sbjct: 143 KAEIFTEASEDIMEGHFSKFIDENKEGNFYILSSKFNLMSNRLEESLLNLRKEKIFLKNI 202 Query: 174 LSDISHQLKTPLAALIVFNENLLNDPHMKEEMRTKFLDRSRLQLERMEWLIISLLKLARV 233 +SDISHQLKTPL++LI+FNE L+ D +M E R FL S QL RMEWLII+LLK+ R+ Sbjct: 203 ISDISHQLKTPLSSLIMFNE-LMKDENMPIEDRKNFLKLSDEQLRRMEWLIINLLKIGRL 261 Query: 234 EAGAITFQKERVRVREMIDHAVHSLRMLSEQRKQQIHIHGGEAMYVWADEEWLTEAIINL 293 EAG + F++E + ++ A+ L ++++ QQ+ + E +Y D +W EAI N+ Sbjct: 262 EAGVVEFRRENNPLYVTVNKALAGLSEKAKEKSQQVIVDIDEDVYFKHDMDWTAEAISNI 321 Query: 294 IKNALEHTPLEGAIDVILEENSVFQTVIIRDRGEGISSEDLPHIFERFYSGRSTEKPQXX 353 IKN++EHT G I + EE + T+ I+D GEGI + IFERFY G ++ P Sbjct: 322 IKNSIEHTDSYGQIKISCEETPISLTISIKDNGEGIPEKLQNKIFERFYKGENSVNPSSI 381 Query: 354 XXXXXXXXXXXEEQGGMITVVSQLGIGTEFRISFNK 389 E Q G I V S++G GTEF ++F K Sbjct: 382 GIGLSLTKSIIESQNGSIIVESEMGEGTEFIMTFLK 417 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.135 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,038,923,724 Number of extensions: 75932339 Number of successful extensions: 300518 Number of sequences better than 1.0e-05: 17315 Number of HSP's gapped: 286370 Number of HSP's successfully gapped: 17345 Length of query: 397 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 259 Effective length of database: 1,760,596,133 Effective search space: 455994398447 Effective search space used: 455994398447 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 132 (55.5 bits)