BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0391.0012.p (364 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C5D456.1 C5D456_9BACI Glu/Leu/Phe/Val dehydrogenase 590 e-167 C3BPQ5.1 C3BPQ5_9BACI Leucine dehydrogenase 587 e-166 C3B7Y4.1 C3B7Y4_BACMY Leucine dehydrogenase 587 e-166 Q75TA6.1 Q75TA6_GEOKA Leucine dehydrogenase EC=1.4.1.9 586 e-165 B7YCI0.1 B7YCI0_9BACI Glu/Leu/Phe/Val dehydrogenase 586 e-165 >C5D456.1 C5D456_9BACI Glu/Leu/Phe/Val dehydrogenase Length = 367 Score = 590 bits (1520), Expect = e-167, Method: Compositional matrix adjust. Identities = 279/364 (76%), Positives = 320/364 (87%) Query: 1 MELFAAMERDDYEELLFCQDKASGLKAIIAIHDTTLGPALGGTRMWTYASEEDAIVDALR 60 MELF ME+ DYE+LLFCQDK SGLKAIIAIHDTTLGPALGGTRMW Y SEE+AI DALR Sbjct: 1 MELFKYMEQYDYEQLLFCQDKESGLKAIIAIHDTTLGPALGGTRMWMYNSEEEAIEDALR 60 Query: 61 LSKGMTYKNAVAGLNLGGGKTVIIGDPKKDKNEAMFRAFGRYIQGLNGRYITAEDVGTTE 120 L++GMTYKNA AGLNLGGGKTVIIGDP+KDKNEAMFRAFGR+IQGLNGRYITAEDVGTT Sbjct: 61 LARGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEAMFRAFGRFIQGLNGRYITAEDVGTTV 120 Query: 121 ADMDIIHQETDYVTGISATYGSSGNPSPATAFGVYQGMKAAAKAAFGSDSLEGRRVAVQG 180 DMDII+QETDYVTGIS +GSSGNPSPATA+GVY+GMKAAAK AFGSDSLEG+ VAVQG Sbjct: 121 EDMDIIYQETDYVTGISPEFGSSGNPSPATAYGVYRGMKAAAKEAFGSDSLEGKVVAVQG 180 Query: 181 VGNVSFTLCKYLHEEGAQLIVTDINKDAVKRAVEAYGATAVDPADIISVKSDIYAPCALG 240 VGNV++ LC++LHEEGAQLIVTDINK+AV+RAVE +GA AVDP DI V DI+APCALG Sbjct: 181 VGNVAYHLCRHLHEEGAQLIVTDINKEAVQRAVEEFGAKAVDPNDIYGVDCDIFAPCALG 240 Query: 241 ATINDDSLPLLQAKVIAGAANNQLKEPRHGDALHKMGIVYAPDYVINSGGVINVADELNG 300 IND ++P L+AKVIAG+ANNQLKE RHGD +H+MGIVYAPDYVIN+GGVINVADEL G Sbjct: 241 GIINDQTIPQLKAKVIAGSANNQLKEARHGDIIHEMGIVYAPDYVINAGGVINVADELYG 300 Query: 301 YNKDRAYKQIAKIYDSITRILEISATSGIPAYAAADHLAQERISLLKNSRSTFLRDGHHV 360 YN++RA K+I +IYD+I ++ I+ GIP Y AAD LA+ERI ++ SRS FL++GHH+ Sbjct: 301 YNRERAMKKIEQIYDNIEKVFAIAKRDGIPTYKAADRLAEERIETMRKSRSQFLQNGHHI 360 Query: 361 LSRR 364 LSRR Sbjct: 361 LSRR 364 >C3BPQ5.1 C3BPQ5_9BACI Leucine dehydrogenase Length = 368 Score = 587 bits (1514), Expect = e-166, Method: Compositional matrix adjust. Identities = 274/364 (75%), Positives = 326/364 (89%) Query: 1 MELFAAMERDDYEELLFCQDKASGLKAIIAIHDTTLGPALGGTRMWTYASEEDAIVDALR 60 +E+F +E+ DYE+++FCQDK SGLKAIIAIHDTTLGPALGGTRMWTY SEE AI DALR Sbjct: 5 LEIFEYLEKYDYEQVVFCQDKESGLKAIIAIHDTTLGPALGGTRMWTYDSEEAAIEDALR 64 Query: 61 LSKGMTYKNAVAGLNLGGGKTVIIGDPKKDKNEAMFRAFGRYIQGLNGRYITAEDVGTTE 120 L+KGMTYKNA AGLNLGG KTVIIGDP+KDK+EAMFRA GRYIQGLNGRYITAEDVGTT Sbjct: 65 LAKGMTYKNAAAGLNLGGAKTVIIGDPRKDKSEAMFRALGRYIQGLNGRYITAEDVGTTV 124 Query: 121 ADMDIIHQETDYVTGISATYGSSGNPSPATAFGVYQGMKAAAKAAFGSDSLEGRRVAVQG 180 DMDIIH+ETD+VTGIS ++GSSGNPSP TA+GVY+GMKAAAK AFG+DSLEG+ +AVQG Sbjct: 125 DDMDIIHEETDFVTGISPSFGSSGNPSPVTAYGVYRGMKAAAKEAFGTDSLEGKVIAVQG 184 Query: 181 VGNVSFTLCKYLHEEGAQLIVTDINKDAVKRAVEAYGATAVDPADIISVKSDIYAPCALG 240 VGNV++ LCK+LH EGAQLIVTDINK+AV+RAVE +GATAV+P +I V+ DIYAPCALG Sbjct: 185 VGNVAYHLCKHLHAEGAQLIVTDINKEAVQRAVEEFGATAVEPNEIYGVECDIYAPCALG 244 Query: 241 ATINDDSLPLLQAKVIAGAANNQLKEPRHGDALHKMGIVYAPDYVINSGGVINVADELNG 300 AT+ND+++P L+AKVIAG+ANNQLKE RHGDA+H+MGIVYAPDYVIN+GGVINVADEL G Sbjct: 245 ATVNDETIPQLKAKVIAGSANNQLKEDRHGDAIHEMGIVYAPDYVINAGGVINVADELYG 304 Query: 301 YNKDRAYKQIAKIYDSITRILEISATSGIPAYAAADHLAQERISLLKNSRSTFLRDGHHV 360 YN++RA K++ IYD+I +++EIS G+P Y AAD LA+ERI+ LKN+RSTFLR+GH + Sbjct: 305 YNRERALKRVESIYDTIAKVIEISKRDGVPTYVAADRLAEERIASLKNTRSTFLRNGHDI 364 Query: 361 LSRR 364 +SRR Sbjct: 365 ISRR 368 >C3B7Y4.1 C3B7Y4_BACMY Leucine dehydrogenase Length = 368 Score = 587 bits (1514), Expect = e-166, Method: Compositional matrix adjust. Identities = 274/364 (75%), Positives = 326/364 (89%) Query: 1 MELFAAMERDDYEELLFCQDKASGLKAIIAIHDTTLGPALGGTRMWTYASEEDAIVDALR 60 +E+F +E+ DYE+++FCQDK SGLKAIIAIHDTTLGPALGGTRMWTY SEE AI DALR Sbjct: 5 LEIFEYLEKYDYEQVVFCQDKESGLKAIIAIHDTTLGPALGGTRMWTYDSEEAAIEDALR 64 Query: 61 LSKGMTYKNAVAGLNLGGGKTVIIGDPKKDKNEAMFRAFGRYIQGLNGRYITAEDVGTTE 120 L+KGMTYKNA AGLNLGG KTVIIGDP+KDK+EAMFRA GRYIQGLNGRYITAEDVGTT Sbjct: 65 LAKGMTYKNAAAGLNLGGAKTVIIGDPRKDKSEAMFRALGRYIQGLNGRYITAEDVGTTV 124 Query: 121 ADMDIIHQETDYVTGISATYGSSGNPSPATAFGVYQGMKAAAKAAFGSDSLEGRRVAVQG 180 DMDIIH+ETD+VTGIS ++GSSGNPSP TA+GVY+GMKAAAK AFG+DSLEG+ +AVQG Sbjct: 125 DDMDIIHEETDFVTGISPSFGSSGNPSPVTAYGVYRGMKAAAKEAFGTDSLEGKVIAVQG 184 Query: 181 VGNVSFTLCKYLHEEGAQLIVTDINKDAVKRAVEAYGATAVDPADIISVKSDIYAPCALG 240 VGNV++ LCK+LH EGAQLIVTDINK+AV+RAVE +GATAV+P +I V+ DIYAPCALG Sbjct: 185 VGNVAYHLCKHLHAEGAQLIVTDINKEAVQRAVEEFGATAVEPNEIYGVECDIYAPCALG 244 Query: 241 ATINDDSLPLLQAKVIAGAANNQLKEPRHGDALHKMGIVYAPDYVINSGGVINVADELNG 300 AT+ND+++P L+AKVIAG+ANNQLKE RHGDA+H+MGIVYAPDYVIN+GGVINVADEL G Sbjct: 245 ATVNDETIPQLKAKVIAGSANNQLKEDRHGDAIHEMGIVYAPDYVINAGGVINVADELYG 304 Query: 301 YNKDRAYKQIAKIYDSITRILEISATSGIPAYAAADHLAQERISLLKNSRSTFLRDGHHV 360 YN++RA K++ IYD+I +++EIS G+P Y AAD LA+ERI+ LKN+RSTFLR+GH + Sbjct: 305 YNRERALKRVESIYDTIAKVIEISKRDGVPTYVAADRLAEERIASLKNTRSTFLRNGHDI 364 Query: 361 LSRR 364 +SRR Sbjct: 365 ISRR 368 >Q75TA6.1 Q75TA6_GEOKA Leucine dehydrogenase EC=1.4.1.9 Length = 367 Score = 586 bits (1510), Expect = e-165, Method: Compositional matrix adjust. Identities = 274/364 (75%), Positives = 320/364 (87%) Query: 1 MELFAAMERDDYEELLFCQDKASGLKAIIAIHDTTLGPALGGTRMWTYASEEDAIVDALR 60 MELF ME+ DYE++LFCQDK SGLKAII IHDTTLGPALGGTRMW Y SEE+A+ DALR Sbjct: 1 MELFQYMEKYDYEQVLFCQDKESGLKAIIVIHDTTLGPALGGTRMWMYNSEEEALEDALR 60 Query: 61 LSKGMTYKNAVAGLNLGGGKTVIIGDPKKDKNEAMFRAFGRYIQGLNGRYITAEDVGTTE 120 L++GMTYKNA AGLNLGGGKTVIIGDP+KDKNEAMFRAFGR+IQGLNGRYITAEDVGTT Sbjct: 61 LARGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEAMFRAFGRFIQGLNGRYITAEDVGTTV 120 Query: 121 ADMDIIHQETDYVTGISATYGSSGNPSPATAFGVYQGMKAAAKAAFGSDSLEGRRVAVQG 180 ADMDII+QETDYVTGIS +GSSGNPSPATA+GVY+GMKAAAK AFGSDSLEG+ VAVQG Sbjct: 121 ADMDIIYQETDYVTGISPEFGSSGNPSPATAYGVYRGMKAAAKEAFGSDSLEGKVVAVQG 180 Query: 181 VGNVSFTLCKYLHEEGAQLIVTDINKDAVKRAVEAYGATAVDPADIISVKSDIYAPCALG 240 VGNV++ LC++LHEEGA+LIVTDINK+AV RAVE +GA AVDP DI V+ DI+APCALG Sbjct: 181 VGNVAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAVDPNDIYGVECDIFAPCALG 240 Query: 241 ATINDDSLPLLQAKVIAGAANNQLKEPRHGDALHKMGIVYAPDYVINSGGVINVADELNG 300 IND ++P L+AKVIAG+ANNQLKEPRHGD +H+MGIVYAPDYVIN+GGVINVADEL G Sbjct: 241 GIINDQTIPQLKAKVIAGSANNQLKEPRHGDMIHEMGIVYAPDYVINAGGVINVADELYG 300 Query: 301 YNKDRAYKQIAKIYDSITRILEISATSGIPAYAAADHLAQERISLLKNSRSTFLRDGHHV 360 YN++RA K+I +IYD+I ++ I+ IP Y AAD +A+ERI ++ +RS FL++GHH+ Sbjct: 301 YNRERAMKKIEQIYDNIEKVFAIAKRDNIPTYVAADRMAEERIETMRKARSQFLQNGHHI 360 Query: 361 LSRR 364 LSRR Sbjct: 361 LSRR 364 >B7YCI0.1 B7YCI0_9BACI Glu/Leu/Phe/Val dehydrogenase Length = 367 Score = 586 bits (1510), Expect = e-165, Method: Compositional matrix adjust. Identities = 274/364 (75%), Positives = 320/364 (87%) Query: 1 MELFAAMERDDYEELLFCQDKASGLKAIIAIHDTTLGPALGGTRMWTYASEEDAIVDALR 60 MELF ME+ DYE++LFCQDK SGLKAII IHDTTLGPALGGTRMW Y SEE+A+ DALR Sbjct: 1 MELFQYMEKYDYEQVLFCQDKESGLKAIIVIHDTTLGPALGGTRMWMYNSEEEALEDALR 60 Query: 61 LSKGMTYKNAVAGLNLGGGKTVIIGDPKKDKNEAMFRAFGRYIQGLNGRYITAEDVGTTE 120 L++GMTYKNA AGLNLGGGKTVIIGDP+KDKNEAMFRAFGR+IQGLNGRYITAEDVGTT Sbjct: 61 LARGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEAMFRAFGRFIQGLNGRYITAEDVGTTV 120 Query: 121 ADMDIIHQETDYVTGISATYGSSGNPSPATAFGVYQGMKAAAKAAFGSDSLEGRRVAVQG 180 ADMDII+QETDYVTGIS +GSSGNPSPATA+GVY+GMKAAAK AFGSDSLEG+ VAVQG Sbjct: 121 ADMDIIYQETDYVTGISPEFGSSGNPSPATAYGVYRGMKAAAKEAFGSDSLEGKVVAVQG 180 Query: 181 VGNVSFTLCKYLHEEGAQLIVTDINKDAVKRAVEAYGATAVDPADIISVKSDIYAPCALG 240 VGNV++ LC++LHEEGA+LIVTDINK+AV RAVE +GA AVDP DI V+ DI+APCALG Sbjct: 181 VGNVAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAVDPNDIYGVECDIFAPCALG 240 Query: 241 ATINDDSLPLLQAKVIAGAANNQLKEPRHGDALHKMGIVYAPDYVINSGGVINVADELNG 300 IND ++P L+AKVIAG+ANNQLKEPRHGD +H+MGIVYAPDYVIN+GGVINVADEL G Sbjct: 241 GIINDQTIPQLKAKVIAGSANNQLKEPRHGDMIHEMGIVYAPDYVINAGGVINVADELYG 300 Query: 301 YNKDRAYKQIAKIYDSITRILEISATSGIPAYAAADHLAQERISLLKNSRSTFLRDGHHV 360 YN++RA K+I +IYD+I ++ I+ IP Y AAD +A+ERI ++ +RS FL++GHH+ Sbjct: 301 YNRERAMKKIEQIYDNIEKVFAIAKRDNIPTYVAADRMAEERIETMRKARSQFLQNGHHI 360 Query: 361 LSRR 364 LSRR Sbjct: 361 LSRR 364 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.316 0.133 0.378 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,083,667,353 Number of extensions: 86039929 Number of successful extensions: 266288 Number of sequences better than 1.0e-05: 1452 Number of HSP's gapped: 264224 Number of HSP's successfully gapped: 1452 Length of query: 364 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 227 Effective length of database: 1,770,017,148 Effective search space: 401793892596 Effective search space used: 401793892596 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 132 (55.5 bits)