BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0391.0006.p (568 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K9V8.1 B3K9V8_9BACI Sensor protein EC=2.7.13.3 440 e-121 B3K9V7.1 B3K9V7_9BACI Sensor protein EC=2.7.13.3 411 e-113 B1DH04.1 B1DH04_9BACL Sensor protein EC=2.7.13.3 347 2e-93 B1DFG4.1 B1DFG4_9BACL Histidine kinase A domain protein 275 9e-72 C0ZI77.1 C0ZI77_BREBN Sporulation kinase B EC=2.7.3.- 139 1e-30 >B3K9V8.1 B3K9V8_9BACI Sensor protein EC=2.7.13.3 Length = 629 Score = 440 bits (1132), Expect = e-121, Method: Compositional matrix adjust. Identities = 233/520 (44%), Positives = 335/520 (64%), Gaps = 11/520 (2%) Query: 33 IPDWEMKW-ETSDVCDPXXXXXXPDSEWVQAGMDSVRPAAPADASAVWFRFPLPLTEERN 91 I +W++ W ET V D +W+ + P+ P ++ W + +P + Sbjct: 37 IKEWKILWSETRGVPDSVPAHR---DDWLVTSTGASTPSKPHAKASAWIQMKIPEISSAS 93 Query: 92 PALLINKVTGHNLRAYADHKLIYESQDLMNYDERKVLIPLSGTEGHSWLYLWSSXXXXXX 151 P +LI+K+ G + YADH+ IYES NY+ +L+PL LY+W Sbjct: 94 PGILIDKLHGQQVAVYADHEKIYESTRTYNYELNYILLPLHQDLLGKDLYIWLETARDHV 153 Query: 152 XXXXXXTAGNYGKLLEFYVKQNLPDMVIGAAFLFVGAALMGCXXXXXXXXXXXXXXXXXX 211 GNY LL +VK NL D+++G+AF+F+ ++ C Sbjct: 154 TMEGKILVGNYHDLLNQFVKSNLVDIILGSAFVFIALVMLICAVFLNRKYLITVLSLSFI 213 Query: 212 IVSFGVLFITYSPFLPVIL-HIPDHWTQIGFDLALFTLLPSFTIYFEQIFGAGKHRVITK 270 I+S G+L TYSPFL I + +TQ+ +D++LF LLPSF+++FE+IFG G V+ K Sbjct: 214 ILSVGILVFTYSPFLYTIFDEYGNLYTQL-YDISLFILLPSFSLFFEKIFGPGWRGVLRK 272 Query: 271 LRKFQLGYSLFCLVFLIVNAMLSYRLDGLYRIATVDFLGLLMMAQFIYLLFVTLGAAFKG 330 LRKFQ+ YSLFC +FLI N + LY +V LG +M+ QF+ L+ ++ A KG Sbjct: 273 LRKFQVFYSLFCGLFLIFNQWAFNQWFDLYYFFSVQVLGFVMIVQFVLLVGSSMYYAVKG 332 Query: 331 NRDAVIFSAGFSIFALLSLTELILYY-ANNSYHLQWWKWGVIAFVASLILILGRRFAGNH 389 N+DA+IF+AGF++FA++ L EL+ ++ SY+L WKWG+++F+ +LI+ILGR FA NH Sbjct: 333 NKDAIIFNAGFAVFAIVGLGELLQFFLTRGSYNLFLWKWGIVSFIIALIVILGRHFAKNH 392 Query: 390 EQVLEYSRDLEKFNDDLQRSEKMEIISELAASVAHEVRNPLQVTRGFLQILGERSDKKEK 449 EQ+L+YS++LE FN++LQRSEKMEIISELAASVAHEVRNPLQVTRGFLQ+L ++ E+ Sbjct: 393 EQMLQYSKELEMFNNELQRSEKMEIISELAASVAHEVRNPLQVTRGFLQLLTGKAQSTER 452 Query: 450 EYLQMAMEELDRASLIITDFLTFAKP--GMDTLDRFEVEEELRHVSGVLVPLAHLQGGTI 507 EYL +A+ ELDRAS IITDFLTFAKP G DT+ R + EE +H+ G+L PLAHLQGG I Sbjct: 453 EYLDLALVELDRASGIITDFLTFAKPEFGKDTVLR--ISEEFKHIEGILGPLAHLQGGRI 510 Query: 508 ELNLESGLQVLGSTSKFKQAFINLIKNAIESLEEDGQITV 547 +++ + + G++SKFKQAFIN++KN+IE+L ++G + + Sbjct: 511 TVDIPEDITIRGNSSKFKQAFINIVKNSIEALGDEGLVHI 550 >B3K9V7.1 B3K9V7_9BACI Sensor protein EC=2.7.13.3 Length = 637 Score = 411 bits (1057), Expect = e-113, Method: Compositional matrix adjust. Identities = 217/520 (41%), Positives = 319/520 (61%), Gaps = 8/520 (1%) Query: 33 IPDWEMKW--ETSDVCDPXXXXXXPDSEWVQAGMDSVRPAAPADASAVWFRFPLPLTEER 90 IPDW+ W E +V P S W+ ++ P S+ W RF LP + Sbjct: 38 IPDWQFMWDNEQQEVVSPAGIRN--SSGWLTGTPENKEPPKSDGVSSAWNRFTLPDLPWK 95 Query: 91 NPALLINKVTGHNLRAYADHKLIYESQDLMNYDERKVLIPLSGTEGHSWLYLWSSXXXXX 150 A++I+++ G ++ A+ + + +YE++ Y +L+P + +Y+W++ Sbjct: 96 QSAIMIDRIKGQDVLAFLNDEPVYEAKRDYMYTNHSLLLPFHPDDAGKTVYIWTNGSSDM 155 Query: 151 XXXXXXXTA-GNYGKLLEFYVKQNLPDMVIGAAFLFVGAALMGCXXXXXXXXXXXXXXXX 209 G Y L ++K++L D ++G++FLF+ + C Sbjct: 156 TLGIDSEIMLGEYDDLRRGFIKKDLEDFILGSSFLFIAVVMFFCCLFLPKHTVSSWLSLS 215 Query: 210 XXIVSFGVLFITYSPFLPVIL-HIPDHWTQIGFDLALFTLLPSFTIYFEQIFGAGKHRVI 268 I++ G L ITYSPFL + W + FD++LFT+LP+ YFE+I+G G +R+I Sbjct: 216 VIILASGALLITYSPFLYTFYGELGSVWVSV-FDISLFTVLPALYFYFEKIYGPGPYRII 274 Query: 269 TKLRKFQLGYSLFCLVFLIVNAMLSYRLDGLYRIATVDFLGLLMMAQFIYLLFVTLGAAF 328 R+ Q+ YS CLVFL V+ + + +Y +V LG+L++ Q + L+ T+ A Sbjct: 275 RYGRRIQMAYSGICLVFLAVHVLSHHSFYDMYYFFSVKILGILIILQMVLLIGTTILYAA 334 Query: 329 KGNRDAVIFSAGFSIFALLSLTELI-LYYANNSYHLQWWKWGVIAFVASLILILGRRFAG 387 K N+DA IF+AGF + A+ +L +++ YY + Y L WKWGVI + SLI++LGR+FA Sbjct: 335 KRNKDAYIFTAGFGMMAIATLGDMLAFYYHDGHYELFLWKWGVIGLIVSLIILLGRKFAR 394 Query: 388 NHEQVLEYSRDLEKFNDDLQRSEKMEIISELAASVAHEVRNPLQVTRGFLQILGERSDKK 447 +HEQVL+YSR+LE FN +LQRSEKMEIISELAASVAHEVRNPLQVTRGF+Q+L E S + Sbjct: 395 SHEQVLQYSRELEMFNQELQRSEKMEIISELAASVAHEVRNPLQVTRGFMQLLAENSKQT 454 Query: 448 EKEYLQMAMEELDRASLIITDFLTFAKPGMDTLDRFEVEEELRHVSGVLVPLAHLQGGTI 507 EKEY +A++ELDRAS IITDFLTFAKP ++ R V EEL+HV G+L+PLA+L GGTI Sbjct: 455 EKEYFGLALKELDRASGIITDFLTFAKPELEHETRLNVYEELKHVKGILLPLANLSGGTI 514 Query: 508 ELNLESGLQVLGSTSKFKQAFINLIKNAIESLEEDGQITV 547 EL+ L + G++SK KQA IN++KN+IE+L+ +G I + Sbjct: 515 ELDDAKELYINGNSSKLKQAMINIVKNSIEALDGEGVIRI 554 >B1DH04.1 B1DH04_9BACL Sensor protein EC=2.7.13.3 Length = 626 Score = 347 bits (889), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 201/545 (36%), Positives = 307/545 (56%), Gaps = 8/545 (1%) Query: 7 IFMLFLLISIVPIGIAVQWGGGAGFSIPDWEMKWETSDVCDPXXXXXXPDSEWVQAGMDS 66 IF+LF +I I I + + ++ +W+ D P W+ + Sbjct: 9 IFILFSIIVITSISPTITFANTDESALKIRITEWQLHPGNDEDSKIP-PADGWITVRENE 67 Query: 67 VRPAAPADASAVWFRFPLPLTEERNPALLINKVTGHNLRAYADHKLIYESQDLMNYDERK 126 P P S++W + LP+ + + LL++K N+ AY + + +YE++ +YD + Sbjct: 68 KEPVLPKGTSSLWLKVDLPVITQSHAGLLVSKAYAQNVFAYLNEENVYETKRNHSYDVNR 127 Query: 127 VLIPLSGTEGHSWLYLWSSXXXXXXXXXXXXTAGNYGKLLEFYVKQNLPDMVIGAAFLFV 186 +IP+ T + LY+ G Y KL + ++ ++++G AF+F+ Sbjct: 128 FVIPIERTSTNETLYI-HLVNHTGNIGITGLAIGEYSKLYRTMLMSDVDNIILGTAFIFI 186 Query: 187 GAALMGCXXXXXXXXXXXXXXXXXXIVSFGVLFITYSPFLPVILHIPDHWTQIGFDLALF 246 A + C I S G + I YSPFL ++ GFDL+ Sbjct: 187 AALMFICMIFLKRIHVSGWKSLSLIIFSIGCMLIFYSPFLYMVNEKYGWLYATGFDLSSN 246 Query: 247 TLLPSFTIYFEQIFGAGKHRVITKLRKFQLGYSLFCLVFLIVNAMLSYRLDGLY-RIATV 305 LP+ + E FG GK +I + + LG + + LI+N M + LY +ATV Sbjct: 247 LFLPALFFFLETFFGRGKFAIIRIFKIYALGSMILSTIGLILNIMTNNAFYSLYYSVATV 306 Query: 306 DF-LGLLMMAQFIYLLFVTLGAAFKGNRDAVIFSAGFSIFALLSLTELILYYA-NNSYHL 363 F LG+L + + V + K NRDA+I SAG S F L ++ ++I YY+ + +Y Sbjct: 307 LFVLGVLGGCSIVIGVLVV--HSIKKNRDAIILSAGLSFFILFAVADIIQYYSLSKNYEF 364 Query: 364 QWWKWGVIAFVASLILILGRRFAGNHEQVLEYSRDLEKFNDDLQRSEKMEIISELAASVA 423 +WKWG + FV +L+++LGR+ E+V+ YSR LE FN++LQRSEKM++IS+LAASVA Sbjct: 365 VYWKWGTVCFVFTLVVMLGRQIVIGFEKVVTYSRQLEIFNNELQRSEKMDMISQLAASVA 424 Query: 424 HEVRNPLQVTRGFLQILGERS-DKKEKEYLQMAMEELDRASLIITDFLTFAKPGMDTLDR 482 HEVRNPLQVTRGFLQ+L E+S KEK Y+ +A+ ELDRAS IITDFLTFAKP ++ + Sbjct: 425 HEVRNPLQVTRGFLQLLEEKSGSNKEKNYMLLAINELDRASEIITDFLTFAKPQLEHVSV 484 Query: 483 FEVEEELRHVSGVLVPLAHLQGGTIELNLESGLQVLGSTSKFKQAFINLIKNAIESLEED 542 + E +H+ +L+PLA++QGG I LN+ LQ+ G++SKFKQAFIN+IKN+IE+L+ + Sbjct: 485 LNIANEFKHIGTILIPLANMQGGQIRLNIPDHLQINGNSSKFKQAFINMIKNSIEALKNE 544 Query: 543 GQITV 547 G+I + Sbjct: 545 GRIDI 549 >B1DFG4.1 B1DFG4_9BACL Histidine kinase A domain protein Length = 537 Score = 275 bits (703), Expect = 9e-72, Method: Compositional matrix adjust. Identities = 161/482 (33%), Positives = 270/482 (56%), Gaps = 10/482 (2%) Query: 33 IPDWEMKW--ETSDVCDPXXXXXXPDSEWVQAGMDSVRPAAPADASAVWFRFPLPLTEER 90 I DW+ +W + + ++W A D A A A+ R LP + Sbjct: 38 IKDWDYQWLYKPDESYQAAWIEEGDPNKWQHAETDQPMQNRAAGADALLLRITLPSLDWN 97 Query: 91 NPALLINKVTGHNLRAYADHK--LIYESQDLMNYDERKVLIPLS-GTEGHSWLYLWSSXX 147 P + + +V G + +H+ L+Y + YD L+PL+ T+G++ L L Sbjct: 98 TPGIWMKRVYGTAVSVAYEHQDGLLYNMERSYPYDVNYTLLPLTDATKGNNLLILLH-LS 156 Query: 148 XXXXXXXXXXTAGNYGKLLEFYVKQNLPDMVIGAAFLFVGAALMGCXXXXXXXXXXXXXX 207 G+Y +++ Y + L ++V G +F+F+ +M C Sbjct: 157 DERQSLEPELVIGDYNEMMPDYERYGLIELVYGGSFMFIALIMMTCLFFLKREQIVLWMS 216 Query: 208 XXXXIVSFGVLFITYSPFLPVILHIPDHWTQIGFDLALFTLLPSFTIYFEQIFGAGKHRV 267 I+ G + + YSP L + FDLALF L P+ ++FEQ G G + + Sbjct: 217 LCLIILCLGEIILAYSPALYHHYYAYGRPFLDLFDLALFLLTPALAVFFEQTLGPGIYGI 276 Query: 268 ITKLRKFQLGYSLFCLVFLIVNAMLSYRLDGL-YRIATVDFLGLLMMAQFIYLLFVTLGA 326 I K R + ++ +V + + + G+ + V L ++ QF+ L +G Sbjct: 277 IKKFRIVLIPVTVMVIVLWALGKTI---VPGISLSLLQVVPLTVIAAIQFLILTVHAIGY 333 Query: 327 AFKGNRDAVIFSAGFSIFALLSLTELILYYANNSYHLQWWKWGVIAFVASLILILGRRFA 386 A++GNRDA++ S G+S+F + ++E+I+Y+ + +YHL +WKWG++ F+ SLI ++GR+F+ Sbjct: 334 AWRGNRDAIMISVGYSVFCSVFISEIIIYFRDETYHLIYWKWGLLVFLLSLIAVMGRQFS 393 Query: 387 GNHEQVLEYSRDLEKFNDDLQRSEKMEIISELAASVAHEVRNPLQVTRGFLQILGERSDK 446 NH+Q+++YS++LE FN ++QR EKME+IS LAAS+AHEVRNPLQVTRGF+Q++GE++ Sbjct: 394 RNHDQLVKYSKELEMFNREIQRGEKMELISHLAASIAHEVRNPLQVTRGFIQLVGEKAVN 453 Query: 447 KEKEYLQMAMEELDRASLIITDFLTFAKPGMDTLDRFEVEEELRHVSGVLVPLAHLQGGT 506 K+K++LQ+A++ELDRAS IIT+FLTFAKP ++ + + EEL + ++ PLA +Q + Sbjct: 454 KDKQFLQLAVQELDRASSIITEFLTFAKPHLEDIKTLNISEELNQIQDIISPLAAMQALS 513 Query: 507 IE 508 ++ Sbjct: 514 LK 515 >C0ZI77.1 C0ZI77_BREBN Sporulation kinase B EC=2.7.3.- Length = 442 Score = 139 bits (349), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 69/157 (43%), Positives = 102/157 (64%), Gaps = 2/157 (1%) Query: 393 LEYSRDLEKFNDDLQRSEKMEIISELAASVAHEVRNPLQVTRGFLQILGERSDKKEKEYL 452 +E+ R+ ++RSEK+ +ISELAASVAHEVRNPL V RGF+Q+L E ++ K EY+ Sbjct: 190 IEFIRESHIIRKQVERSEKLNLISELAASVAHEVRNPLTVVRGFVQLLREETNPKNVEYI 249 Query: 453 QMAMEELDRASLIITDFLTFAKPGMDTLDRFEVEEELRHVSGVLVPLAHLQGGTIELNLE 512 ++ + ELDRA II+D+L AKP +TL+R E+ ++ V+ ++ + + I E Sbjct: 250 RLVLNELDRAEFIISDYLNLAKPHSETLERLEIAHTVKEVTAIMSSYSVMNRVEIACETE 309 Query: 513 SGLQVLGSTSKFKQAFINLIKNAIESLEEDG--QITV 547 GL V + K KQA +NL+KN IES+ + G Q+TV Sbjct: 310 PGLFVESNAVKLKQALMNLMKNGIESMGQGGILQVTV 346 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.324 0.140 0.423 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,091,353,325 Number of extensions: 122741972 Number of successful extensions: 348274 Number of sequences better than 1.0e-05: 2652 Number of HSP's gapped: 352859 Number of HSP's successfully gapped: 2652 Length of query: 568 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 427 Effective length of database: 1,732,333,088 Effective search space: 739706228576 Effective search space used: 739706228576 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 134 (56.2 bits)