BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0391.0004.p (597 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K9V8.1 B3K9V8_9BACI Sensor protein EC=2.7.13.3 565 e-159 B3K9V7.1 B3K9V7_9BACI Sensor protein EC=2.7.13.3 528 e-148 B1DH04.1 B1DH04_9BACL Sensor protein EC=2.7.13.3 456 e-126 B1DFG4.1 B1DFG4_9BACL Histidine kinase A domain protein 286 5e-75 C3DPD2.1 C3DPD2_BACTS Putative uncharacterized protein 207 3e-51 >B3K9V8.1 B3K9V8_9BACI Sensor protein EC=2.7.13.3 Length = 629 Score = 565 bits (1455), Expect = e-159, Method: Compositional matrix adjust. Identities = 281/586 (47%), Positives = 380/586 (64%), Gaps = 7/586 (1%) Query: 4 GSPDGDTGQEVPLGETQGWIKVDARQGTPELPKGISSAWTRITLPESQYTSPAVYIKTLY 63 G PD VP W+ TP P +SAW ++ +PE SP + I L+ Sbjct: 49 GVPD-----SVP-AHRDDWLVTSTGASTPSKPHAKASAWIQMKIPEISSASPGILIDKLH 102 Query: 64 ALHVKVYAGERLIFEGSRSYIHDNYSLLIPLSTEDQGTTLYIWTATLQDRIGIKDRVAVG 123 V VYA I+E +R+Y ++ +L+PL + G LYIW T +D + ++ ++ VG Sbjct: 103 GQQVAVYADHEKIYESTRTYNYELNYILLPLHQDLLGKDLYIWLETARDHVTMEGKILVG 162 Query: 124 EHSNLLKDYSKNGLADIVLGGAFLFVALVLFVCTFYLSKEYFSIATALSLVIASTGVLSI 183 + +LL + K+ L DI+LG AF+F+ALV+ +C +L+++Y +LS +I S G+L Sbjct: 163 NYHDLLNQFVKSNLVDIILGSAFVFIALVMLICAVFLNRKYLITVLSLSFIILSVGILVF 222 Query: 184 TYSPFTYTFFSYLGPXXXXXXXXXXXXXXXXXXXXXEKIFGSGKFAIIRRFRKFQVAYSL 243 TYSPF YT F G EKIFG G ++R+ RKFQV YSL Sbjct: 223 TYSPFLYTIFDEYGNLYTQLYDISLFILLPSFSLFFEKIFGPGWRGVLRKLRKFQVFYSL 282 Query: 244 FCIACLIVNTLSGNRLVEFYYVVSATIVGVIMILQFILLIACVILFSLRGNKDAITFAIG 303 FC LI N + N+ + YY S ++G +MI+QF+LL+ + ++++GNKDAI F G Sbjct: 283 FCGLFLIFNQWAFNQWFDLYYFFSVQVLGFVMIVQFVLLVGSSMYYAVKGNKDAIIFNAG 342 Query: 304 FGTAALTGAVELAWYYYRQGNYDLIYWKWAXXXXXXXXXXXXXXXXAHNHQQVVKYSREL 363 F A+ G EL ++ +G+Y+L WKW A NH+Q+++YS+EL Sbjct: 343 FAVFAIVGLGELLQFFLTRGSYNLFLWKWGIVSFIIALIVILGRHFAKNHEQMLQYSKEL 402 Query: 364 ELFNNELQRSEKMEIISELAASVAHEVRNPLQVTRGFLQLLSEKSSGDERKYLSMALSEL 423 E+FNNELQRSEKMEIISELAASVAHEVRNPLQVTRGFLQLL+ K+ ER+YL +AL EL Sbjct: 403 EMFNNELQRSEKMEIISELAASVAHEVRNPLQVTRGFLQLLTGKAQSTEREYLDLALVEL 462 Query: 424 DRASNIITDFLTFAKPEFEKISQLSVLDECKHIESIMLPLCHLNGGKMVLEVTGDLWVKG 483 DRAS IITDFLTFAKPEF K + L + +E KHIE I+ PL HL GG++ +++ D+ ++G Sbjct: 463 DRASGIITDFLTFAKPEFGKDTVLRISEEFKHIEGILGPLAHLQGGRITVDIPEDITIRG 522 Query: 484 NSSKFKQAFINMIKNSIESLGEDGSIHIKAYAKGDKVFIHIKDNGAGMDPAVLSRLGEPY 543 NSSKFKQAFIN++KNSIE+LG++G +HI+ Y + +VFIH+ DNG GM P VL+RLGEPY Sbjct: 523 NSSKFKQAFINIVKNSIEALGDEGLVHIRCYRQQGQVFIHVVDNGEGMGPDVLARLGEPY 582 Query: 544 FSSNKTKGTGLGLMVTFRIIEAMGGEVRFISSKGAGTESITILPLA 589 F SNKTKGTGLGLMVTFRIIEAM G++ F S +G GT+++ LP A Sbjct: 583 F-SNKTKGTGLGLMVTFRIIEAMDGDIYFTSKQGVGTDAVITLPAA 627 >B3K9V7.1 B3K9V7_9BACI Sensor protein EC=2.7.13.3 Length = 637 Score = 528 bits (1360), Expect = e-148, Method: Compositional matrix adjust. Identities = 269/586 (45%), Positives = 368/586 (62%), Gaps = 2/586 (0%) Query: 3 WGSPDGDTGQEVPLGETQGWIKVDARQGTPELPKGISSAWTRITLPESQYTSPAVYIKTL 62 W + + + + GW+ P G+SSAW R TLP+ + A+ I + Sbjct: 45 WDNEQQEVVSPAGIRNSSGWLTGTPENKEPPKSDGVSSAWNRFTLPDLPWKQSAIMIDRI 104 Query: 63 YALHVKVYAGERLIFEGSRSYIHDNYSLLIPLSTEDQGTTLYIWTATLQDR-IGIKDRVA 121 V + + ++E R Y++ N+SLL+P +D G T+YIWT D +GI + Sbjct: 105 KGQDVLAFLNDEPVYEAKRDYMYTNHSLLLPFHPDDAGKTVYIWTNGSSDMTLGIDSEIM 164 Query: 122 VGEHSNLLKDYSKNGLADIVLGGAFLFVALVLFVCTFYLSKEYFSIATALSLVIASTGVL 181 +GE+ +L + + K L D +LG +FLF+A+V+F C +L K S +LS++I ++G L Sbjct: 165 LGEYDDLRRGFIKKDLEDFILGSSFLFIAVVMFFCCLFLPKHTVSSWLSLSVIILASGAL 224 Query: 182 SITYSPFTYTFFSYLGPXXXXXXXXXXXXXXXXXXXXXEKIFGSGKFAIIRRFRKFQVAY 241 ITYSPF YTF+ LG EKI+G G + IIR R+ Q+AY Sbjct: 225 LITYSPFLYTFYGELGSVWVSVFDISLFTVLPALYFYFEKIYGPGPYRIIRYGRRIQMAY 284 Query: 242 SLFCIACLIVNTLSGNRLVEFYYVVSATIVGVIMILQFILLIACVILFSLRGNKDAITFA 301 S C+ L V+ LS + + YY S I+G+++ILQ +LLI IL++ + NKDA F Sbjct: 285 SGICLVFLAVHVLSHHSFYDMYYFFSVKILGILIILQMVLLIGTTILYAAKRNKDAYIFT 344 Query: 302 IGFGTAALTGAVELAWYYYRQGNYDLIYWKWAXXXXXXXXXXXXXXXXAHNHQQVVKYSR 361 GFG A+ ++ +YY G+Y+L WKW A +H+QV++YSR Sbjct: 345 AGFGMMAIATLGDMLAFYYHDGHYELFLWKWGVIGLIVSLIILLGRKFARSHEQVLQYSR 404 Query: 362 ELELFNNELQRSEKMEIISELAASVAHEVRNPLQVTRGFLQLLSEKSSGDERKYLSMALS 421 ELE+FN ELQRSEKMEIISELAASVAHEVRNPLQVTRGF+QLL+E S E++Y +AL Sbjct: 405 ELEMFNQELQRSEKMEIISELAASVAHEVRNPLQVTRGFMQLLAENSKQTEKEYFGLALK 464 Query: 422 ELDRASNIITDFLTFAKPEFEKISQLSVLDECKHIESIMLPLCHLNGGKMVLEVTGDLWV 481 ELDRAS IITDFLTFAKPE E ++L+V +E KH++ I+LPL +L+GG + L+ +L++ Sbjct: 465 ELDRASGIITDFLTFAKPELEHETRLNVYEELKHVKGILLPLANLSGGTIELDDAKELYI 524 Query: 482 KGNSSKFKQAFINMIKNSIESLGEDGSIHIKAYAKGDKVFIHIKDNGAGMDPAVLSRLGE 541 GNSSK KQA IN++KNSIE+L +G I I AYA+ +V IHI+D+G G++ L RLGE Sbjct: 525 NGNSSKLKQAMINIVKNSIEALDGEGVIRIWAYAESGEVVIHIQDDGIGIEAGDLERLGE 584 Query: 542 PYFSSNKTKGTGLGLMVTFRIIEAMGGEVRFISSKGAGTESITILP 587 YF SNK+KGTGLGLMVTFRIIEAM G + FIS KG+GTE+I P Sbjct: 585 AYF-SNKSKGTGLGLMVTFRIIEAMRGTIHFISEKGSGTEAIIRFP 629 >B1DH04.1 B1DH04_9BACL Sensor protein EC=2.7.13.3 Length = 626 Score = 456 bits (1174), Expect = e-126, Method: Compositional matrix adjust. Identities = 251/586 (42%), Positives = 347/586 (59%), Gaps = 7/586 (1%) Query: 6 PDGDTGQEVPLGETQGWIKVDARQGTPELPKGISSAWTRITLPESQYTSPAVYIKTLYAL 65 P D ++P + GWI V + P LPKG SS W ++ LP + + + YA Sbjct: 46 PGNDEDSKIPPAD--GWITVRENEKEPVLPKGTSSLWLKVDLPVITQSHAGLLVSKAYAQ 103 Query: 66 HVKVYAGERLIFEGSRSYIHDNYSLLIPLSTEDQGTTLYIWTATLQDRIGIKDRVAVGEH 125 +V Y E ++E R++ +D +IP+ TLYI IGI +A+GE+ Sbjct: 104 NVFAYLNEENVYETKRNHSYDVNRFVIPIERTSTNETLYIHLVNHTGNIGITG-LAIGEY 162 Query: 126 SNLLKDYSKNGLADIVLGGAFLFVALVLFVCTFYLSKEYFSIATALSLVIASTGVLSITY 185 S L + + + +I+LG AF+F+A ++F+C +L + + S +LSL+I S G + I Y Sbjct: 163 SKLYRTMLMSDVDNIILGTAFIFIAALMFICMIFLKRIHVSGWKSLSLIIFSIGCMLIFY 222 Query: 186 SPFTYTFFSYLGPXXXXXXXXXXXXXXXXXXXXXEKIFGSGKFAIIRRFRKFQVAYSLFC 245 SPF Y G E FG GKFAIIR F+ + + + Sbjct: 223 SPFLYMVNEKYGWLYATGFDLSSNLFLPALFFFLETFFGRGKFAIIRIFKIYALGSMILS 282 Query: 246 IACLIVNTLSGNRLVEFYYVVSATIVGVIMILQFI-LLIACVILFSLRGNKDAITFAIGF 304 LI+N ++ N YY V AT++ V+ +L ++I +++ S++ N+DAI + G Sbjct: 283 TIGLILNIMTNNAFYSLYYSV-ATVLFVLGVLGGCSIVIGVLVVHSIKKNRDAIILSAGL 341 Query: 305 GTAALTGAVELAWYYYRQGNYDLIYWKWAXXXXXXXXXXXXXXXXAHNHQQVVKYSRELE 364 L ++ YY NY+ +YWKW ++VV YSR+LE Sbjct: 342 SFFILFAVADIIQYYSLSKNYEFVYWKWGTVCFVFTLVVMLGRQIVIGFEKVVTYSRQLE 401 Query: 365 LFNNELQRSEKMEIISELAASVAHEVRNPLQVTRGFLQLLSEKS-SGDERKYLSMALSEL 423 +FNNELQRSEKM++IS+LAASVAHEVRNPLQVTRGFLQLL EKS S E+ Y+ +A++EL Sbjct: 402 IFNNELQRSEKMDMISQLAASVAHEVRNPLQVTRGFLQLLEEKSGSNKEKNYMLLAINEL 461 Query: 424 DRASNIITDFLTFAKPEFEKISQLSVLDECKHIESIMLPLCHLNGGKMVLEVTGDLWVKG 483 DRAS IITDFLTFAKP+ E +S L++ +E KHI +I++PL ++ GG++ L + L + G Sbjct: 462 DRASEIITDFLTFAKPQLEHVSVLNIANEFKHIGTILIPLANMQGGQIRLNIPDHLQING 521 Query: 484 NSSKFKQAFINMIKNSIESLGEDGSIHIKAYAKGDKVFIHIKDNGAGMDPAVLSRLGEPY 543 NSSKFKQAFINMIKNSIE+L +G I I Y +G++V I IKDNG GM A L +LGEPY Sbjct: 522 NSSKFKQAFINMIKNSIEALKNEGRIDISGYMEGNRVVICIKDNGEGMTEAELVKLGEPY 581 Query: 544 FSSNKTKGTGLGLMVTFRIIEAMGGEVRFISSKGAGTESITILPLA 589 + SNK+KGTGLGLMVTF IIE M G++ F S KG GTE P A Sbjct: 582 Y-SNKSKGTGLGLMVTFSIIEVMQGDIVFKSIKGIGTEVTVTFPTA 626 >B1DFG4.1 B1DFG4_9BACL Histidine kinase A domain protein Length = 537 Score = 286 bits (731), Expect = 5e-75, Method: Compositional matrix adjust. Identities = 157/456 (34%), Positives = 245/456 (53%), Gaps = 9/456 (1%) Query: 17 GETQGWIKVDARQGTPELPKGISSAWTRITLPESQYTSPAVYIKTLYALHVKVYAGER-- 74 G+ W + Q G + RITLP + +P +++K +Y V V + Sbjct: 61 GDPNKWQHAETDQPMQNRAAGADALLLRITLPSLDWNTPGIWMKRVYGTAVSVAYEHQDG 120 Query: 75 LIFEGSRSYIHD-NYSLLIPLSTEDQGTTLYIWTATLQDRIGIKDRVAVGEHSNLLKDYS 133 L++ RSY +D NY+LL PL+ +G L I +R ++ + +G+++ ++ DY Sbjct: 121 LLYNMERSYPYDVNYTLL-PLTDATKGNNLLILLHLSDERQSLEPELVIGDYNEMMPDYE 179 Query: 134 KNGLADIVLGGAFLFVALVLFVCTFYLSKEYFSIATALSLVIASTGVLSITYSPFTYTFF 193 + GL ++V GG+F+F+AL++ C F+L +E + +L L+I G + + YSP Y + Sbjct: 180 RYGLIELVYGGSFMFIALIMMTCLFFLKREQIVLWMSLCLIILCLGEIILAYSPALYHHY 239 Query: 194 SYLGPXXXXXXXXXXXXXXXXXXXXXEKIFGSGKFAIIRRFRKFQVAYSLFCIACLIV-N 252 G E+ G G + II++FR + ++ I + Sbjct: 240 YAYGRPFLDLFDLALFLLTPALAVFFEQTLGPGIYGIIKKFRIVLIPVTVMVIVLWALGK 299 Query: 253 TLSGNRLVEFYYVVSATIVGVIMILQFILLIACVILFSLRGNKDAITFAIGFGTAALTGA 312 T+ + VV T++ I QF++L I ++ RGN+DAI ++G+ Sbjct: 300 TIVPGISLSLLQVVPLTVIAAI---QFLILTVHAIGYAWRGNRDAIMISVGYSVFCSVFI 356 Query: 313 VELAWYYYRQGNYDLIYWKWAXXXXXXXXXXXXXXXXAHNHQQVVKYSRELELFNNELQR 372 E+ Y+R Y LIYWKW + NH Q+VKYS+ELE+FN E+QR Sbjct: 357 SEII-IYFRDETYHLIYWKWGLLVFLLSLIAVMGRQFSRNHDQLVKYSKELEMFNREIQR 415 Query: 373 SEKMEIISELAASVAHEVRNPLQVTRGFLQLLSEKSSGDERKYLSMALSELDRASNIITD 432 EKME+IS LAAS+AHEVRNPLQVTRGF+QL+ EK+ ++++L +A+ ELDRAS+IIT+ Sbjct: 416 GEKMELISHLAASIAHEVRNPLQVTRGFIQLVGEKAVNKDKQFLQLAVQELDRASSIITE 475 Query: 433 FLTFAKPEFEKISQLSVLDECKHIESIMLPLCHLNG 468 FLTFAKP E I L++ +E I+ I+ PL + Sbjct: 476 FLTFAKPHLEDIKTLNISEELNQIQDIISPLAAMQA 511 >C3DPD2.1 C3DPD2_BACTS Putative uncharacterized protein Length = 424 Score = 207 bits (527), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 103/237 (43%), Positives = 151/237 (63%), Gaps = 2/237 (0%) Query: 358 KYSRELELFNNELQRSEKMEIISELAASVAHEVRNPLQVTRGFLQLLSEKSSGDERKYLS 417 +Y E L E+Q+SEK+ I+SELAASVAHEVRNPL V RGF+QLL + Y+ Sbjct: 189 EYLNENALLRTEMQKSEKLNIVSELAASVAHEVRNPLTVVRGFIQLLESTEDVKNKDYMR 248 Query: 418 MALSELDRASNIITDFLTFAKPEFEKISQLSVLDECKHIESIMLPLCHLNGGKMVLEVTG 477 + L+ELDRA II+D+L A+P+ EK + + + + ++M + G + +E++ Sbjct: 249 LVLAELDRAEQIISDYLNLARPQIEKKEHICLSAQLIEMTTLMSSFAAMQGVYLQVEISE 308 Query: 478 DLWVKGNSSKFKQAFINMIKNSIESL-GEDGSIHIKAYAKGDKVFIHIKDNGAGMDPAVL 536 L+ G+ +K KQA +N++KN IE++ G G + + A KG+ + I +KD+G GM L Sbjct: 309 SLYTIGDKTKLKQAIMNVVKNGIEAIQGNKGYLKVTAIQKGETIIIRVKDSGVGMTKEQL 368 Query: 537 SRLGEPYFSSNKTKGTGLGLMVTFRIIEAMGGEVRFISSKGAGTESITILPLAEAPE 593 +RLG+PY+S K KGTGLGLMVTF I++A G + + S G GTE+I ILP + E Sbjct: 369 ARLGQPYYSL-KEKGTGLGLMVTFSILQAHNGTLEYKSESGKGTEAIIILPAVQNKE 424 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.137 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,303,748,024 Number of extensions: 134246109 Number of successful extensions: 431065 Number of sequences better than 1.0e-05: 22055 Number of HSP's gapped: 410748 Number of HSP's successfully gapped: 22079 Length of query: 597 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 455 Effective length of database: 1,722,912,073 Effective search space: 783924993215 Effective search space used: 783924993215 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)