BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0389.0005.p (249 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q8R7C8.1 GPMA_THETN 2,3-bisphosphoglycerate-dependent phosphogly... 313 9e-84 Q2Y9Z7.1 GPMA2_NITMU 2,3-bisphosphoglycerate-dependent phosphogl... 308 3e-82 C4ETJ3.1 C4ETJ3_9BACT Phosphoglycerate mutase EC=5.4.2.1 303 1e-80 B0KBW9.1 GPMA_THEP3 2,3-bisphosphoglycerate-dependent phosphogly... 295 4e-78 B3X6J8.1 B3X6J8_SHIDY 2,3-bisphosphoglycerate-dependent phosphog... 294 4e-78 >Q8R7C8.1 GPMA_THETN 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase EC=5.4.2.1 Length = 249 Score = 313 bits (802), Expect = 9e-84, Method: Compositional matrix adjust. Identities = 143/247 (57%), Positives = 198/247 (80%) Query: 1 MYEIVLIRHGESEYNRQNLFTGWSDPDLTEKGVEEAKAAGKLLREAGYTFDLAFASVLKR 60 MY++VL+RHGES +N +N FTGW+D DL+ KG+EEAK AGK+L+E G+TFD AF SVLKR Sbjct: 1 MYKVVLLRHGESIWNMENRFTGWTDVDLSPKGIEEAKQAGKILKEKGFTFDAAFTSVLKR 60 Query: 61 SIKTLNYVLDEMDLLWIPVQKSWKLNERHYGALQGLSKSETAVKYGEEQLHIWRRSLSVR 120 +I+TL VLDE+DL+WIPV KSW+LNERHYGALQGL+K+ETA KYGEEQ+ +WRRS VR Sbjct: 61 AIRTLWIVLDELDLMWIPVYKSWRLNERHYGALQGLNKAETAKKYGEEQVKLWRRSAEVR 120 Query: 121 PPMLDPDDPRYARNDIRYKEVRPGDIPRGESLEDTVHRVGDFWGNRIVPLIRKKERVLIS 180 PP L DDPRY ND RY ++ +IP E+L DT++RV +W + I P I+ +RV+I+ Sbjct: 121 PPALTKDDPRYPGNDPRYADLSEDEIPLTENLIDTINRVIPYWESTIAPTIKSGKRVIIA 180 Query: 181 AHGNTLRALIKFMEDIDEKALLDLNVPTGVPLVYKLDDDVKPISRFYLGEPEEVQEKARE 240 AHGN+LR L+K+++++ + +++LN+PTG+PLVY+LD+++KPI +YL + EE+++K +E Sbjct: 181 AHGNSLRGLVKYLDNLSNEEIMELNIPTGIPLVYELDENLKPIRHYYLADEEELKKKQQE 240 Query: 241 VANQSKV 247 VA Q K Sbjct: 241 VAEQGKA 247 >Q2Y9Z7.1 GPMA2_NITMU 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2 EC=5.4.2.1 Length = 251 Score = 308 bits (788), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 141/247 (57%), Positives = 191/247 (77%) Query: 1 MYEIVLIRHGESEYNRQNLFTGWSDPDLTEKGVEEAKAAGKLLREAGYTFDLAFASVLKR 60 M ++VL+RHGES +N++N FTGW+D DLT KG EEA +G+LLREAG+TFD+A+ SVLKR Sbjct: 1 MKKLVLLRHGESTWNKENRFTGWTDVDLTPKGAEEAHNSGRLLREAGFTFDIAYTSVLKR 60 Query: 61 SIKTLNYVLDEMDLLWIPVQKSWKLNERHYGALQGLSKSETAVKYGEEQLHIWRRSLSVR 120 +I+TL VLDEMD +WIPV+ SW+LNERHYGALQGL+K ETAV YGEEQ+ IWRRS +R Sbjct: 61 AIRTLWIVLDEMDQMWIPVESSWRLNERHYGALQGLNKLETAVAYGEEQVLIWRRSYDIR 120 Query: 121 PPMLDPDDPRYARNDIRYKEVRPGDIPRGESLEDTVHRVGDFWGNRIVPLIRKKERVLIS 180 PP L PDDPRY D RY+ + DIP E L+DTV R +W I P ++ + VLI+ Sbjct: 121 PPALTPDDPRYPGCDPRYRNLPKQDIPLTECLQDTVSRFLPYWRESIAPQVKSDKSVLIT 180 Query: 181 AHGNTLRALIKFMEDIDEKALLDLNVPTGVPLVYKLDDDVKPISRFYLGEPEEVQEKARE 240 AHGN+LRAL+ +++++ E +++LN+PTG+PLVY+LDD +KPI +YLG+ ++++ + Sbjct: 181 AHGNSLRALVMYLDNLSEGEIMELNIPTGIPLVYELDDGLKPIRSYYLGDQAKIEQAMQV 240 Query: 241 VANQSKV 247 VANQ K+ Sbjct: 241 VANQGKI 247 >C4ETJ3.1 C4ETJ3_9BACT Phosphoglycerate mutase EC=5.4.2.1 Length = 249 Score = 303 bits (775), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 139/247 (56%), Positives = 198/247 (80%) Query: 1 MYEIVLIRHGESEYNRQNLFTGWSDPDLTEKGVEEAKAAGKLLREAGYTFDLAFASVLKR 60 MY+IVL+RHGES++N++N FTGW+D DL+ KG+EEA+ AG+ L+E G+TFDLA+ SVLKR Sbjct: 1 MYKIVLVRHGESQWNQENRFTGWTDVDLSPKGIEEARKAGRTLKEEGFTFDLAYTSVLKR 60 Query: 61 SIKTLNYVLDEMDLLWIPVQKSWKLNERHYGALQGLSKSETAVKYGEEQLHIWRRSLSVR 120 +I+TL + +EMDL+WIPV+ SW+LNERHYGALQGL+K+ETA KYGEEQ+ IWRRS VR Sbjct: 61 AIRTLWLIQEEMDLMWIPVKPSWRLNERHYGALQGLNKAETAEKYGEEQVKIWRRSYDVR 120 Query: 121 PPMLDPDDPRYARNDIRYKEVRPGDIPRGESLEDTVHRVGDFWGNRIVPLIRKKERVLIS 180 PPML+ D R D RY+++ +P GE L+DTV RV +W + IVP +++ +VL+ Sbjct: 121 PPMLNQGDERDPILDPRYRDLPRELVPLGECLKDTVARVLPYWNDEIVPSLKEGRKVLLV 180 Query: 181 AHGNTLRALIKFMEDIDEKALLDLNVPTGVPLVYKLDDDVKPISRFYLGEPEEVQEKARE 240 AHGN++RAL+K+++++ ++ +L+LN+PTG+PL+Y+LD++ KPIS YLG+PEE+ + + Sbjct: 181 AHGNSIRALVKYLDNVSDQDILELNIPTGIPLLYELDENFKPISSRYLGDPEEIAKAQQA 240 Query: 241 VANQSKV 247 VANQ K Sbjct: 241 VANQGKA 247 >B0KBW9.1 GPMA_THEP3 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase EC=5.4.2.1 Length = 251 Score = 295 bits (754), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 141/247 (57%), Positives = 195/247 (78%) Query: 1 MYEIVLIRHGESEYNRQNLFTGWSDPDLTEKGVEEAKAAGKLLREAGYTFDLAFASVLKR 60 M+++VL+RHGES +N +N FTGW+D DL+ KG+EEA+ +GK L+ GYTFD AF SVLKR Sbjct: 1 MHKVVLLRHGESLWNMENRFTGWTDVDLSPKGIEEARESGKTLKAEGYTFDCAFTSVLKR 60 Query: 61 SIKTLNYVLDEMDLLWIPVQKSWKLNERHYGALQGLSKSETAVKYGEEQLHIWRRSLSVR 120 +I+TL VLDE+D +WIPV KSW+LNERHYGALQGL+K+ETA KYGEEQ+ IWRRS+ VR Sbjct: 61 AIRTLWIVLDELDRMWIPVYKSWRLNERHYGALQGLNKAETAKKYGEEQVKIWRRSVDVR 120 Query: 121 PPMLDPDDPRYARNDIRYKEVRPGDIPRGESLEDTVHRVGDFWGNRIVPLIRKKERVLIS 180 PP L+ DDPRY D RY ++ +IP E+L DT++RV +W + I P I+ ++VLI Sbjct: 121 PPALEKDDPRYPGFDPRYADLSEEEIPLTENLIDTINRVIPYWESTIAPTIKSGKKVLIV 180 Query: 181 AHGNTLRALIKFMEDIDEKALLDLNVPTGVPLVYKLDDDVKPISRFYLGEPEEVQEKARE 240 AHGN+LR L+K+++++ ++ +++LN+PTG+PLVY+LDDD+KPI +YL + E+V+EK Sbjct: 181 AHGNSLRGLVKYLDNLSKQEIMELNIPTGIPLVYELDDDLKPIRHYYLADEEKVKEKKEL 240 Query: 241 VANQSKV 247 V NQ K+ Sbjct: 241 VENQGKI 247 >B3X6J8.1 B3X6J8_SHIDY 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase EC=5.4.2.1 Length = 250 Score = 294 bits (753), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 141/245 (57%), Positives = 190/245 (77%) Query: 3 EIVLIRHGESEYNRQNLFTGWSDPDLTEKGVEEAKAAGKLLREAGYTFDLAFASVLKRSI 62 ++VL+RHGES++N++N FTGW D DL+EKGV EAKAAGKLL+E GY+FD A+ SVLKR+I Sbjct: 5 KLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAI 64 Query: 63 KTLNYVLDEMDLLWIPVQKSWKLNERHYGALQGLSKSETAVKYGEEQLHIWRRSLSVRPP 122 TL VLDE+D W+PV+KSWKLNERHYGALQGL+K+ETA KYG+EQ+ WRR +V PP Sbjct: 65 HTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPP 124 Query: 123 MLDPDDPRYARNDIRYKEVRPGDIPRGESLEDTVHRVGDFWGNRIVPLIRKKERVLISAH 182 L DD RY +D RY ++ ++P ESL T+ RV +W I+P ++ ERVLI+AH Sbjct: 125 ELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNETILPRMKSGERVLIAAH 184 Query: 183 GNTLRALIKFMEDIDEKALLDLNVPTGVPLVYKLDDDVKPISRFYLGEPEEVQEKAREVA 242 GN+LRAL+K+++++ E+ +L+LN+PTGVPLVY+ D++ KP+ R+YLG +E+ KA VA Sbjct: 185 GNSLRALVKYLDNMSEEEILELNIPTGVPLVYEFDENFKPLKRYYLGNADEIAAKAAAVA 244 Query: 243 NQSKV 247 NQ K Sbjct: 245 NQGKA 249 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.137 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,565,651,336 Number of extensions: 66207799 Number of successful extensions: 163838 Number of sequences better than 1.0e-05: 1755 Number of HSP's gapped: 163920 Number of HSP's successfully gapped: 1761 Length of query: 249 Length of database: 3,060,696,203 Length adjustment: 132 Effective length of query: 117 Effective length of database: 1,817,122,223 Effective search space: 212603300091 Effective search space used: 212603300091 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 129 (54.3 bits)