BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0386.0036.p (508 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q2RLZ7.1 Q2RLZ7_MOOTA Transcriptional regulator 214 2e-53 Q2RGM2.1 Q2RGM2_MOOTA Transcriptional regulator, CdaR family 205 1e-50 C0GEC1.1 C0GEC1_9FIRM Transcriptional regulator, CdaR 181 2e-43 C1TND5.1 C1TND5_9BACT Sugar diacid utilization regulator 180 3e-43 O32138.1 PUCR_BACSU Purine catabolism regulatory protein 173 4e-41 >Q2RLZ7.1 Q2RLZ7_MOOTA Transcriptional regulator Length = 558 Score = 214 bits (544), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 166/558 (29%), Positives = 278/558 (49%), Gaps = 73/558 (13%) Query: 5 GITLRELMQLPILSKATVISGMQGLDRVVRFVDVMEVPDLKGWISEGVMLLTTAYSIRHD 64 GIT+RE ++L L +A V++G GL+R++++VD++E+PD +GW +++TT Y+IR+D Sbjct: 2 GITVREALKLGGLRRAKVVAGEAGLERIIKYVDILEIPDPRGWFRANELIITTGYAIRND 61 Query: 65 PSLLTELIYTLDQLGAAALAIKPARFLKEIPQGAIEASNDCGLPIVEIPPEIPYTDITQP 124 P L+ L + A LA+K RF+ +P+ +++ +P++++P +IPY +IT P Sbjct: 62 PRAQANLLLELARTNGAGLAVKFGRFIGSVPEEMRRLADELKIPLLDVPDDIPYVEITNP 121 Query: 125 VMELLLGRQAMLLRRAEEVYRTLTTMVLENSGIQAVSDNVADFLKAPVALLDTERNII-- 182 +M ++ QA L +E V+R LT + LE S IQAV+ +A ++ V + D E + Sbjct: 122 LMAAIVNEQARQLEYSERVHRELTRVALEASNIQAVAAALATLVEREVVICDEELQPLAV 181 Query: 183 ---VSSPSQFDWSL------------AERPLS---WNIHVDRRTVAR-----------LL 213 VS SL A++ + W+ +V RR +L Sbjct: 182 SGAVSGKGSAGGSLQLPPEEIKRLHSAQKAVEITLWSRNVRRRYFVAPIDVREHRYGYIL 241 Query: 214 VDKEQ-LDDMEEVGIEQARLVFALELMRKKVAEDTEFRLRGNFIDELLTPPLPSRHEVER 272 VD + L ++ ++ +E A V AL++++++ + L+ + +++L+ L R Sbjct: 242 VDGQTPLSELNQIALEHAVTVTALQMVKEEAVVEARRSLQRDLLEDLIAGALRHRELAIS 301 Query: 273 RARQLGMNPEHKWEVAVIE------------GETAPNEETVNRLLEQEAR-------KRG 313 RA LG+ E + I+ G N + R + +R Sbjct: 302 RAEALGILLEEPKVIMAIDIDDFTGYLLHQPGAQEANAGVLKRRFHRAVNSCFMAFDRRV 361 Query: 314 VTPHAEFRSNRAVLFLPTPEGRKFGVAGDKGTSWAVTLEGWLSDKAEG--------LGGY 365 +T RS+ V LP GR+ A D W V L G L + A L G Sbjct: 362 LTVQ---RSDSVVGILPA-NGREIRGAED----WRV-LRGMLQELAASIQLKIARELDGV 412 Query: 366 RTGVGTPEYLWD---IQTSYNEARKALSVAKRLGQGTGGVTRYEEIEVYHLLEGLSGEGF 422 +G D I Y EAR A+ +A+RL G G V +E++E+YH+L G SGE Sbjct: 413 TVTIGISSIAADPMEISERYQEARTAIRLARRL-NGKGTVAFWEDVELYHVL-GQSGETL 470 Query: 423 AALFERKLGKLRQYDQEHDSNMLLTFYHYLECRGSLIETANSLYIHRNSVKYRLERIRDI 482 + LG+L + + ++ +L T YLEC+G+++ +A LYIHRN+++YRL+RI ++ Sbjct: 471 ERFYRSVLGELDRPEVKNREELLETLRVYLECQGNVMASAAKLYIHRNTMRYRLQRIEEL 530 Query: 483 TGFDLNDPREQFVCHLCL 500 G DL+ P E+ L L Sbjct: 531 LGRDLDSPDERLALWLAL 548 >Q2RGM2.1 Q2RGM2_MOOTA Transcriptional regulator, CdaR family Length = 553 Score = 205 bits (521), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 158/563 (28%), Positives = 273/563 (48%), Gaps = 69/563 (12%) Query: 1 MNTRGITLRELMQLPILSKATVISGMQGLDRVVRFVDVMEVPDLKGWISEGVMLLTTAYS 60 M GIT+RE ++LP L A ++ G QGLDR++ V++MEVPD+ +I +LLTTAY Sbjct: 1 MLIMGITVREALRLPQLEGAVLVGGEQGLDRIINSVNIMEVPDIGNYIKPAELLLTTAYP 60 Query: 61 IRHDPSLLTELIYTLDQLGAAALAIKPARFLKEIPQGAIEASNDCGLPIVEIPPEIPYTD 120 I+ D L LI L++ G AALAIKP R+++EIP+ I+ +N P++++P + + Sbjct: 61 IKDDIRALENLIPELNKCGLAALAIKPERYIREIPEIMIKQANKYKFPLIKLPNSASFNE 120 Query: 121 ITQPVMELLLGRQAMLLRRAEEVYRTLTTMVLENSGIQAVSDNVADFLKAPVALLDTERN 180 I P++ +L RQA +L+R E++ + LT +VL G+ ++ +A L PV++ D Sbjct: 121 IINPILTEILNRQAAILQRNEQLSKALTGIVLYGGGLAEIARTLAGLLGLPVSIHDPAFR 180 Query: 181 IIVS--SPSQF----DWSLAE----------------RPLSWNIHVDRRTVARLLVDKEQ 218 I S +P F + +LAE L +N + R + E+ Sbjct: 181 KIASWLAPRDFGADNNRALAELVNDSKQLAEACKCGREQLVFNCAGGLYAICRPVTVAEE 240 Query: 219 -------------LDDMEEVGIEQARLVFALELMRKKVAEDTEFRLRGNFIDELLTPPLP 265 + + E GIEQA V ALE+ +++ D E R + +FI+ L+ + Sbjct: 241 IYAYLFIWGPQKPISEREITGIEQAVTVIALEISKQRAVFDVESRFKSSFIEYLVDGKIT 300 Query: 266 SRHEVERRARQLGMNPEHKWEVAVIEGETAPNEETVNRLLEQE---ARKR---------- 312 S+ + A + G + + V + E + + L +QE ARK+ Sbjct: 301 SKEDAIILAERFGWEIANGFTVMLFEC------DDLQSLYDQEPVFARKKRLKIMEIVNT 354 Query: 313 ---GVTPHAEF--RSNR-AVLFLPTPEGRKFGVAGDKGTSWAVTLEGWLSDKAEGLGGYR 366 ++P + R R VL P P G+ + A + L+ + + R Sbjct: 355 AVVSLSPGSAVVERGRRLMVLHRPLP-GKDIKQLRRNSETLARSCCEELAKRLDT----R 409 Query: 367 TGVGTPEYLWD---IQTSYNEARKALSVAKRLGQGTGGVTRYEEIEVYHLLEGLSGEGFA 423 VG ++ D I N++ +AL + +R + G V ++++ VY +L Sbjct: 410 ILVGISRFIADPMKIAEGINQSHQALEIGRRAYE-RGQVFHFDDLGVYRILLTSDAAEMQ 468 Query: 424 ALFERKLGKLRQYDQEHDSNMLLTFYHYLECRGSLIETANSLYIHRNSVKYRLERIRDIT 483 ++ LG+L YD+E+ + ++ T +L +TA++L+IH N+++YR+ RI+ IT Sbjct: 469 RFYDDILGQLVSYDEENKAGLITTLEMLFANDMNLQKTADALFIHYNTLRYRINRIQQIT 528 Query: 484 GFDLNDPREQFVCHLCLIYYYLQ 506 G DL P ++ L L +++ Sbjct: 529 GLDLKSPDDRLSLQLALKILHMK 551 >C0GEC1.1 C0GEC1_9FIRM Transcriptional regulator, CdaR Length = 550 Score = 181 bits (458), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 139/551 (25%), Positives = 271/551 (49%), Gaps = 57/551 (10%) Query: 6 ITLRELMQLPILSKATVISGMQGLDRVVRFVDVMEVPDLKGWISEGVMLLTTAYSIRHDP 65 +T+ E + L +L A V +G GL+R +++V+++E+ + +G +L+TTA+ ++ +P Sbjct: 3 LTVHEALHLDVLRDAKVRAGWGGLERKIKWVNILEILEELNVSRDGELLITTAFGLKDNP 62 Query: 66 SLLTELIYTLDQLGAAALAIKPARFLKEIPQGAIEASNDCGLPIVEIPPEIPYTDITQPV 125 L +LI L + G A LAI+ +L+EIP + +N LP+VE+P + + ++++ + Sbjct: 63 GLQQQLIPHLVEKGLACLAIQTGYYLQEIPSVILRQANLHNLPVVELPRDTMFANLSKAI 122 Query: 126 MELLLGRQAMLLRRAEEVYRTLTTMVLENSGIQAVSDNVADFLKAPVALLDTERNI---- 181 + L+ Q +L ++E+ LT +VL+N G+ + +A+ L V L+D + Sbjct: 123 LTRLINHQFQVLSDSQELQHRLTQLVLKNKGLSEILSVLAELLDRKVRLVDNSYRLLAGG 182 Query: 182 IVSSPSQFDWSLA-ERPLSW---------------------NIHVDRRTVARLLV----- 214 ++S + D S A E W + HV + +A ++ Sbjct: 183 VLSDGGEADTSEAIEEEFQWLRKYGILDSLEKDKKAAEVAESKHVSAQIIAPVMSGDTVT 242 Query: 215 -------DKEQLDDMEEVGIEQARLVFALELMRKKVAEDTEFRLRGNFIDELLTPPLPSR 267 D + +++ + QA + +L L+++ DTE RL+G+F+D+LL+ PS Sbjct: 243 AYLSAVGDSQTFSELDLAALYQAATLCSLVLLKEAAVRDTEDRLKGDFLDDLLSGNYPSE 302 Query: 268 HEVERRARQLGMNPEHKW--------EVAVIEGETAPN----EETVNRLLEQEARKRGVT 315 V RRAR LG H+ E +E + P + + L+++ +++ + Sbjct: 303 EIVLRRARFLGYESIHRGVFMLFKANEFETLEELSEPEIIQIKTDLISLIQEALQQKNIH 362 Query: 316 PHAEFRSNRAVLFLPTPEGRKFGVAGDKGTSWAVTLEGWLSDKAEGLGGYRTGVGTP-EY 374 +S V+ L EG F GD A L+ + K + + G+G P Sbjct: 363 SICRLQS-ATVIVLILEEGFLF---GDADVELATELKEEIEQKMKRV-TVSAGLGRPYRE 417 Query: 375 LWDIQTSYNEARKALSVAKRLGQGTGGVTRYEEIEVYHLLEGLSGEGFAALFERKLGKLR 434 L + S+ E KAL +A+++G G+ R+ ++ + LL + A + + ++ Sbjct: 418 LGKLAKSFAEGEKALRIAQKIGDDR-GIFRFSDLGAFRLLLSENEAELNAFYRDTVERIV 476 Query: 435 QYDQEHDSNMLLTFYHYLECRGSLIETANSLYIHRNSVKYRLERIRDITGFDLNDPREQF 494 + D++++ +L + YL+ ++ E A+ L+IHR+++KYRL +I +TG DL++ + Sbjct: 477 EDDRKNNGELLKSLKVYLDENRNIKEAASKLFIHRHTLKYRLNKIAGLTGRDLDNSEDLL 536 Query: 495 VCHLCLIYYYL 505 HL ++ Y+ Sbjct: 537 NLHLGILISYI 547 >C1TND5.1 C1TND5_9BACT Sugar diacid utilization regulator Length = 538 Score = 180 bits (457), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 147/539 (27%), Positives = 251/539 (46%), Gaps = 43/539 (7%) Query: 5 GITLRELMQLPILSKATVISGMQGL-DRVVRFVDVMEVPDLKGWISEGVMLLTTAYSIRH 63 +T++E++ LP + VI+G + R VR V VM+ PD W+ EG +++++ Y + Sbjct: 2 SMTIQEILDLPPMKGLRVIAGAANIASRQVRSVTVMDAPDACSWVREGDLIVSSGYIFKD 61 Query: 64 DPSLLTELIYTLDQLGAAALAIKPARFLKEIPQGAIEASNDCGLPIVEIPPEIPYTDITQ 123 LL +LI +L ++GAA L IK R++KE+P AIE + +P++ +P + DI Sbjct: 62 STELLMDLIKSLAEIGAAGLGIKTDRYIKEVPSKAIELAESSSIPLIHVPNHFAFADIIH 121 Query: 124 PVMELLLGRQAMLLRRAEEVYRTLTTMVLENSGIQAVSDNVADFLKAPVALLDT---ERN 180 PV+ ++ RQA LLR +E V + + + + ++ + +N+ +F P +DT ER Sbjct: 122 PVLSEIVNRQARLLRYSETVRHSFFNLSVNGADLKTILENLQNFTHKPFGFVDTLTGERY 181 Query: 181 II---VSSPSQFDWSLAERPL-----SWNIHVDRRTVARLLVDKEQLDDME---EVGIEQ 229 S S+FD S+ R L +I ++ + LL D +Q D E E+ I Q Sbjct: 182 FFGEAQSLRSRFD-SIPLRDLLSSGTPDSISLNGKVYGYLLFDCKQEDLAERNCEIPITQ 240 Query: 230 ARLVFALELMRKKVAEDTEFRLRGNFIDELLTPPLPSRHEVERRARQLGM---------- 279 A+ L + R+ E R R F+ ++L L EV RA+ G Sbjct: 241 AKGAILLYMQRRVAEIQAESRYRNEFVQDILIHNLRFEGEVWNRAKMFGWDLQGSHCVVV 300 Query: 280 ----NPEHKWEVAVIEGETAPNEETVNRLLEQEARKR-----GVTPHAEFRSNRAVLFLP 330 N +H++E E + P E+ + + + + P+ E S+ LP Sbjct: 301 MDIDNYKHQFEKRSRERDFLPMLESTKKRIYRICKNHVHGLFESVPYTEM-SDSISFILP 359 Query: 331 TPEGRKFGVAGDKGTSWAVTLEGWLSDKAEGLGGYRTGVGTP-EYLWDIQTSYNEARKAL 389 T EG F K T ++ S K + G+G+P + +++ SY+EARKAL Sbjct: 360 TEEG--FPAFKAKTTPLFRDIQT--SIKEDTHFTVTIGIGSPKDSVFECHHSYDEARKAL 415 Query: 390 SVAKRLGQGTGGVTRYEEIEVYHLLEGLSGEGFAALFERK-LGKLRQYDQEHDSNMLLTF 448 + R G VT ++++ Y +L L F R+ +G + +D+ S +L T Sbjct: 416 EMV-RAATGGNRVTFWKDLGAYKILGSLYDTDTGHSFYREYIGPIIDHDKRRKSELLRTL 474 Query: 449 YHYLECRGSLIETANSLYIHRNSVKYRLERIRDITGFDLNDPREQFVCHLCLIYYYLQE 507 + + A L +H +++KYR +I D+ FD D ++ L L Y + + Sbjct: 475 KAMVRNNWQMKAAAKDLSVHYSTLKYRYAKICDLLEFDPEDSEQRLNLALSLKLYLMNQ 533 >O32138.1 PUCR_BACSU Purine catabolism regulatory protein Length = 531 Score = 173 bits (438), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 133/530 (25%), Positives = 242/530 (45%), Gaps = 61/530 (11%) Query: 6 ITLRELMQLPILSKATVISGMQGLDRVVRFVDVMEVPDLKGWISEGVMLLTTAYSIRHDP 65 + + ++M++P A +I+G G +R V+ V++M+ PD+ ++ + +L+TTAY ++ P Sbjct: 1 MNILDVMKIPAFENANLIAGKAGGEREVQHVNMMDAPDIVDFLHKNELLVTTAYHLKDHP 60 Query: 66 SLLTELIYTLDQLGAAALAIKPARFLKEIPQGAIEASNDCGLPIVEIPPEIPYTDITQPV 125 L+ELI + + G A L IK R+L++IP+ IE ++ PI+E+P I DI Sbjct: 61 HQLSELIRQMAKRGCAGLGIKTKRYLEDIPKEIIELADSYAFPIIELPEHIRLGDIVNAT 120 Query: 126 MELLLGRQAMLLRRAEEVYRTLTTMVLENSGIQAVSDNVADFLKAPVALLDTERNIIVSS 185 + +L ++ L++A ++ T ++ G+Q++ V+D L+ PV LLD ++ +S Sbjct: 121 LSHILDMRSNELQQAIYAHKKFTNHIMSGKGLQSLLKKVSDILQLPVLLLDQHAKMLSAS 180 Query: 186 PSQFDWSLAERPLSWNIHV-------------DRRTVARLLVDKEQ-------LDDMEEV 225 S+ L ++ D++T + L + + + DM + Sbjct: 181 ---HQISVETEKLKGTLNTVSGPFFTCFSTISDQKTYSVLPIYNHEKNCGYLLIPDMVQA 237 Query: 226 G-------IEQARLVFALELMRKKVAEDTEFRLRGNFIDELLTPPLPSRHEVERRARQLG 278 G IEQA V + EL+++ + R R F + + S E++ RA++ Sbjct: 238 GDKGLILTIEQAANVISFELLKENALKQFSRRARNEFFNNFIERTFSSDDEIKNRAKEFK 297 Query: 279 MNPEHKWEVAVIEGETAPNEETVN------------RLLEQEARKRGVTPHAEFRSNRAV 326 + + K+ I G+ N+E+++ LE E PH + N + Sbjct: 298 LRWDQKY--MCIAGKLDRNDESISFTENQLASDSVFEFLEGELSAFPFPPHFFMKGNVGI 355 Query: 327 LFLPTPEGRKFGVAGDKGTSWAVTLEGWLSD-KAEGLGGYRTGV-----GTPEYLWDIQT 380 + + A D + ++ +L + + ++ V + L D+ Sbjct: 356 ILIE---------ATDSWSEMHASVISFLEQFQTQVSAQFKRTVSFGISNICQKLIDVPD 406 Query: 381 SYNEARKALSVAKRLGQGTGGVTRYEEIEVYHLLEGLSGEGFAALFERKLGKLRQYDQEH 440 ++ EA AL + L + T + Y +V LL L E + L L + QE Sbjct: 407 AFTEASDALQ-SGHLSRSTAFIQVYHAKDVPELLRLLPVEDLKKFYNSTLQSLAEKQQE- 464 Query: 441 DSNMLLTFYHYLECRGSLIETANSLYIHRNSVKYRLERIRDITGFDLNDP 490 D ++L T YLE + ETA LY+HRN+V YRLE+ ++ G L DP Sbjct: 465 DQSLLHTLSVYLETHCQISETAKRLYVHRNTVIYRLEKCEELLGKSLKDP 514 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.137 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,049,462,289 Number of extensions: 132160081 Number of successful extensions: 336824 Number of sequences better than 1.0e-05: 489 Number of HSP's gapped: 336780 Number of HSP's successfully gapped: 570 Length of query: 508 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 368 Effective length of database: 1,741,754,103 Effective search space: 640965509904 Effective search space used: 640965509904 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)