BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0385.0009.p (582 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KEQ4.1 B3KEQ4_9BACI Histidine kinase internal region 1011 0.0 B3K5P4.1 B3K5P4_9BACI Histidine kinase internal region 411 e-112 B1D7Q6.1 B1D7Q6_9BACL Histidine kinase internal region 266 4e-69 A8RMQ3.1 A8RMQ3_9CLOT Putative uncharacterized protein 216 4e-54 A4XMF9.1 A4XMF9_CALS8 Integral membrane sensor signal transducti... 199 7e-49 >B3KEQ4.1 B3KEQ4_9BACI Histidine kinase internal region Length = 584 Score = 1011 bits (2614), Expect = 0.0, Method: Compositional matrix adjust. Identities = 486/579 (83%), Positives = 531/579 (91%) Query: 4 LDYLRRQSFRSKLKIAFLAVILLSVLMTGGLSYYISAATLEKNALKLTQDTVVRSAQIVD 63 + YLRRQSFR+KLK+AFLAVI+LSVLMTGGLSYYISAATLEKNALKLTQDTVVRSAQIVD Sbjct: 1 MKYLRRQSFRNKLKVAFLAVIVLSVLMTGGLSYYISAATLEKNALKLTQDTVVRSAQIVD 60 Query: 64 EKLNKLMLIMMTFMISQPFHDMLKDAAAGDTSRYYTHLNDLDNVFSQARIAEPLIQSIYV 123 EKLNKLMLIMMTFMISQPF+DMLKDAA+GD SRYYTHLNDLDNVFSQARIAEPLIQSIYV Sbjct: 61 EKLNKLMLIMMTFMISQPFYDMLKDAASGDASRYYTHLNDLDNVFSQARIAEPLIQSIYV 120 Query: 124 STPIGEFYPSSMNRNRLTSFKDTFLYGRIEQEQKNIWVEGHEDMLFSGKDRVISLILEPI 183 TPIGEFYPSSMNRNRLT+F+DT LY RIEQE+KN+WVEGHEDMLFSGK+RVISLILEPI Sbjct: 121 FTPIGEFYPSSMNRNRLTAFEDTVLYSRIEQEKKNLWVEGHEDMLFSGKERVISLILEPI 180 Query: 184 FDTPVSGVYIVVNIREDGFRKLVQGDTGAGAASFLLNAEGKTVYPVKEPLVRQAVDGGNL 243 FDTPVSGVYIVVNIREDGFRKLVQG+T GA+SFLLNA+G TVYPVKE LVRQAV+ G+L Sbjct: 181 FDTPVSGVYIVVNIREDGFRKLVQGNTAEGASSFLLNADGDTVYPVKETLVRQAVETGDL 240 Query: 244 SGMMKSPEGNQSFDLDGKTYLLNYAHLGIADWTMTTIQSQASVLKDMVYVKWLIGXXXXX 303 SG+M EG+Q FDLDG+TYLLNYA LGIADWTMTTI+S+A VL DMVYVKWLI Sbjct: 241 SGLMNRSEGSQPFDLDGQTYLLNYARLGIADWTMTTIRSRADVLHDMVYVKWLIAGVTLA 300 Query: 304 XXXXXXXISGAFTGYLLVPLQGLMKVMKRVESNDLSARFESGSGDELAQVGFRFNRMLEQ 363 ISGAF+ YLL PLQGL+KVMKRVE+NDL+ARFESGSGDELAQVGFRFNRMLEQ Sbjct: 301 AFTVTTLISGAFSRYLLKPLQGLLKVMKRVENNDLTARFESGSGDELAQVGFRFNRMLEQ 360 Query: 364 IVVLIGEVTEAETHKRSAEIKALSAQMDPHFLYNTLNTIYWKLNLKQVEPSQKMVLSLSR 423 IVVLI EVTEA+THKR+AEIKALSAQMDPHFLYNTLNTIYWKL LKQ+EPSQ+MV+SLSR Sbjct: 361 IVVLIDEVTEAQTHKRTAEIKALSAQMDPHFLYNTLNTIYWKLKLKQIEPSQQMVMSLSR 420 Query: 424 LFQLGLNKGQEITTLSKELEHVRQYLELQSSCYEGLFHYEIHVREPELAALSIPRIILQP 483 LFQLGLN GQEITT+SKELEHVRQYLELQ SCYE LF YEIHVREPE++++SIPRIILQP Sbjct: 421 LFQLGLNNGQEITTMSKELEHVRQYLELQLSCYEDLFSYEIHVREPEVSSISIPRIILQP 480 Query: 484 LVENSILHGFRDLESGGRIEIEIAGDGERWVLAVRDNGSGMEEDQVRALFWQESEKGYAV 543 LVENSILHGFRDL++GG IEIEI+GD +RW +AVRDNG GM+E QVRALFW ES+KGYAV Sbjct: 481 LVENSILHGFRDLKNGGLIEIEISGDEKRWTIAVRDNGRGMDEAQVRALFWLESKKGYAV 540 Query: 544 SNLIRRLQLYYGDSAEFYVDSAAGRGTEVRISVPKKGEH 582 SNLIRRL+LYYGD AEF VDSA RGTE+RIS+PKKGEH Sbjct: 541 SNLIRRLRLYYGDGAEFRVDSAPERGTEIRISLPKKGEH 579 >B3K5P4.1 B3K5P4_9BACI Histidine kinase internal region Length = 602 Score = 411 bits (1057), Expect = e-112, Method: Compositional matrix adjust. Identities = 226/579 (39%), Positives = 349/579 (60%), Gaps = 18/579 (3%) Query: 11 SFRSKLKIAFLAVILLSVLMTGGLSYYISAATLEKNALKLTQDTVVRSAQIVDEKLNKLM 70 +F+ +++++F+ +I L++ G +Y+I++ L+KNA + Q+TV ++ QI+D+KL + Sbjct: 22 TFKQRVRLSFIIMITLAIGAVGMTTYWIASKELQKNAFESRQETVNKTTQILDDKLAGIS 81 Query: 71 LIMMTFMISQPFHDMLKDAAAGDTSRYYTHLNDLDNVFSQARIAEPLIQSIYVSTPIGEF 130 + + M S F +M+ D + D S YY HL++L VFSQ EPLI+SI ++TPIG+F Sbjct: 82 NSVRSLMFSYAFKEMMLDVQSNDISNYYVHLSELQYVFSQVTFNEPLIESILIATPIGDF 141 Query: 131 YPSSMNRNRLTSFKDTFLYGRIEQEQKNIWVEGHEDMLFSGKDRVISLILEPIFDT-PVS 189 YP S R++ SF ++ +Y +++ IWV+GH D F+G R +S + + + + Sbjct: 142 YPVSQRRSQTQSFYESSMYYDVKENYGGIWVKGHTDKFFTGNSRTLSFVTKGTQENVSNT 201 Query: 190 GVYIVVNIREDGFRKLV-QGDTGAGAASFLLNAEG----KTVYPVKEPLVRQAVDGGNLS 244 V+IVVN+ E G +V Q + + F+++++G +T + L++ Sbjct: 202 NVFIVVNVNESGLIGMVNQHSSNDDSDYFVIDSKGEEVIRTAWSSSHNLMKDK------P 255 Query: 245 GMMKSPEGNQ-SF--DLDGKTYLLNYAHLGIA-DWTMTTIQSQASVLKDMVYVKWLIGXX 300 + K EGNQ SF D YL+NY + DW++ IQ + +L+ M VK Sbjct: 256 FLYKVSEGNQGSFFHHFDETDYLVNYTRSAVVKDWSLFGIQQKDKLLEQMNGVKRTTFYI 315 Query: 301 XXXXXXXXXXISGAFTGYLLVPLQGLMKVMKRVESNDLSARFESGSGDELAQVGFRFNRM 360 +S T LL PL L ++M+ VE N L+ RF S S DE+AQVG++FNRM Sbjct: 316 MLFFLVLTWLLSTKLTAILLNPLYKLQRLMREVEDNRLNVRFASRSTDEVAQVGYQFNRM 375 Query: 361 LEQIVVLIGEVTEAETHKRSAEIKALSAQMDPHFLYNTLNTIYWKLNLKQVEPSQKMVLS 420 L++I LI +V +E+ KR AE++AL+AQM+PHFLYNTLNTIY K L + + +M+LS Sbjct: 376 LDEINRLIDDVRLSESGKRKAEMRALTAQMEPHFLYNTLNTIYCKSVLGENDEVNEMILS 435 Query: 421 LSRLFQLGLNKGQEITTLSKELEHVRQYLELQSSCYEGLFHYEIHVREPELAALSIPRII 480 LS++FQLGL+ G++ TL EL HV QY LQ CYEGLF +E+ V + L +P+I+ Sbjct: 436 LSQMFQLGLSGGKDWNTLEDELLHVEQYCLLQQKCYEGLFEFEVTVTDDSLLTCLMPKIL 495 Query: 481 LQPLVENSILHGFRDLESGGRIEIEIAGDGERWVLAVRDNGSGMEEDQVRALFWQE--SE 538 LQP+VENSI HGFRD+ SGG+I + + G+ L + DNG GM+ D V + S+ Sbjct: 496 LQPIVENSIQHGFRDIGSGGQIHLHVCRQGQLLYLIIEDNGIGMDADNVMKGMLEPPVSK 555 Query: 539 KGYAVSNLIRRLQLYYGDSAEFYVDSAAGRGTEVRISVP 577 KGYA++N++ RL L+YG+ A + S G+G+ I +P Sbjct: 556 KGYALNNIVNRLSLFYGEDAGIKLTSLPGKGSRTEIWMP 594 >B1D7Q6.1 B1D7Q6_9BACL Histidine kinase internal region Length = 284 Score = 266 bits (680), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 139/273 (50%), Positives = 182/273 (66%), Gaps = 4/273 (1%) Query: 312 SGAFTGYLLVPLQGLMKVMKRVE-SNDLSARFESGSGDELAQVGFRFNRMLEQIVVLIGE 370 S T LL PL L +M +VE SNDLS RFES DE++QVG +FN MLE++ + I E Sbjct: 4 SNILTAILLKPLLKLRNLMVKVEHSNDLSVRFESEYQDEVSQVGRKFNSMLEELALSIKE 63 Query: 371 VTEAETHKRSAEIKALSAQMDPHFLYNTLNTIYWKLNLKQVEPSQKMVLSLSRLFQLGLN 430 E E KR AEIKAL AQ+DPHFLYNTLNTIYWK L Q + ++MVLSLSR+FQLGLN Sbjct: 64 TEEIEIKKRKAEIKALQAQIDPHFLYNTLNTIYWKAQLHQSDEVKEMVLSLSRMFQLGLN 123 Query: 431 KGQEITTLSKELEHVRQYLELQSSCYEGLFHYE--IHVREPELAALSIPRIILQPLVENS 488 G + TTL KE+EHV+QYL +Q CY LF Y+ I + + ++I ++ILQPLVENS Sbjct: 124 NGFDYTTLEKEIEHVKQYLFIQKKCYTNLFDYKVTIDLENDSIIDITILKVILQPLVENS 183 Query: 489 ILHGFRDLESGGRIEIEIAGDGERWVLAVRDNGSGMEEDQVRALFWQESEK-GYAVSNLI 547 ILHGF++ +SGG I I I E V+ V DNG GM D+++ ++K GYA+ N+ Sbjct: 184 ILHGFKNRKSGGLIHIWIRKTEEHLVITVEDNGEGMNVDEIKQSLQVPTQKTGYALRNIY 243 Query: 548 RRLQLYYGDSAEFYVDSAAGRGTEVRISVPKKG 580 RLQLYYG+ +E +S + T + +++ KG Sbjct: 244 HRLQLYYGEDSEMTFESIPDQKTSITLTISMKG 276 >A8RMQ3.1 A8RMQ3_9CLOT Putative uncharacterized protein Length = 620 Score = 216 bits (551), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 172/606 (28%), Positives = 288/606 (47%), Gaps = 52/606 (8%) Query: 9 RQSFRSKLKIAFLAVILLSVLMTGGLSYYISAATLEKNALKLTQDTVVRSAQIVDEKLNK 68 R + K+ ++F A V++TG L YY++A+ + + A T V + Q ++E Sbjct: 26 RLMLKEKMILSFAAASTGIVVLTGALHYYMTASRILEEAEATTVQMVGNACQDINE---- 81 Query: 69 LMLIMMTFMISQPFHD-----MLKDAAAGDTSRYYTHLNDLDNVFSQARIAEPL----IQ 119 L + TF + +D L Y+H DL+ S + P I Sbjct: 82 --LFLQTFQVCSAMNDNISMQKLIRRQFSSIKEMYSH--DLEG--SMEMMVLPSYNRDIF 135 Query: 120 SIYVSTPIGEFYPSSMNRNRLTSFKDTFLYGRIEQEQKNIWVEGHED--MLFSGKDRVIS 177 +YV G Y S+ + ++ +DT Y I + W HE+ ++ + +S Sbjct: 136 GVYVLGDNGGRYKSNSSSFLVSDPRDTDWYRIIHATGQAQWFPPHENSYVVSTPYTSYVS 195 Query: 178 LILEPIFDTPV---SGVYIVVNIREDGFRKLVQGDTGAGAASFLLNAEGKTVY------P 228 + + P D GV ++ +I D + FL++ + + P Sbjct: 196 MGI-PFIDKATGRTKGV-VLADIDSDKLSDIAARAVSGAGDVFLMDERNRIMNLTAGEGP 253 Query: 229 VKEPLVRQAVDGG------NLSGMMKSPEGNQSFDLDGKTYLLNYAHLGIADWTMTTIQS 282 K+ R V+ NLS + PE S L K L+ Y L DW + + Sbjct: 254 WKD---RDGVEKARRMVEENLSEI---PEYGVSHVLKDKGQLVVYQTLNQTDWKIVGVIP 307 Query: 283 QASVLKDMVYVKWLIGXXXXXXXXXXXXISGAFTGYLLVPLQGLMKVMKRVESNDLSARF 342 +AS+ + + Y+K L+ +S + PL L+K M++V + +L Sbjct: 308 KASITRSVEYIKVLMIMLLALAVVISMILSEIVADSVTRPLFTLVKAMEQVCAGNLETSV 367 Query: 343 ESGSGDELAQVGFRFNRMLEQIVVLIGEVTEAETHKRSAEIKALSAQMDPHFLYNTLNTI 402 E+ GDE+ + FN M ++ LI + + R E+KAL AQ++PHFLYNTL++I Sbjct: 368 ETERGDEIGVLYDSFNHMTGEMRNLIDTIYREQEKLRREELKALQAQINPHFLYNTLDSI 427 Query: 403 YWKLNLKQVEPSQKMVLSLSRLFQLGLNKGQEITTLSKELEHVRQYLELQSSCYEGLFHY 462 W L ++QVE S +M+ +L+ F++ L+KG++I T+ +E++H++ YL +Q Y+ F Y Sbjct: 428 IWSLRMRQVEESIEMLTALTDFFKISLSKGRDIITIEEEVKHIKSYLSIQHRRYQEKFDY 487 Query: 463 EIHVREPELAALSIPRIILQPLVENSILHGFRDLESGGRIEIEIAGDGERWVLAVRDNGS 522 +IHV +P + + P++ILQP+VEN+I HG + +E G I I I +L V+D G Sbjct: 488 DIHV-DPSILSCRTPKLILQPVVENAIYHGIKPMEEKGYIYIHIFPQEGDVILQVQDTGM 546 Query: 523 GMEEDQVRALFWQ-------ESEKGYAVSNLIRRLQLYYGDSAEFYVDSAAGRGTEVRIS 575 GM+ED R L + + GY V N+ ++++ YG ++SA G GT V + Sbjct: 547 GMDEDTCRRLNRELDTISSDQQGTGYGVRNVNDKIKIVYGSKYGVTIESAMGEGTVVTLR 606 Query: 576 VPKKGE 581 + KKGE Sbjct: 607 IGKKGE 612 >A4XMF9.1 A4XMF9_CALS8 Integral membrane sensor signal transduction histidine kinase Length = 596 Score = 199 bits (506), Expect = 7e-49, Method: Compositional matrix adjust. Identities = 115/338 (34%), Positives = 185/338 (54%), Gaps = 19/338 (5%) Query: 253 NQSFDLDGKTYLLNYAHLGIADWTMTTIQSQASVLKD------MVYVKWLIGXXXXXXXX 306 N+ + L+ +++ ++W + ++ S + + ++Y++ LI Sbjct: 257 NEIITANSSKLLITSSYIPTSNWRLVSVVSLENAINAIRNSFVLLYIRVLI-----LCLI 311 Query: 307 XXXXISGAFTGYLLVPLQGLMKVMKRVESNDL--SARFESGSGDELAQVGFRFNRMLEQI 364 IS F+ L PLQ L+ MK+V + + + DE+A V +N M+E+I Sbjct: 312 FAFVISMYFSSMLTAPLQKLVSSMKKVRQGNFREQVNIDPHASDEIAIVVSEYNNMVEKI 371 Query: 365 VVLIGEVTEAETHKRSAEIKALSAQMDPHFLYNTLNTIYWKLNLKQVEPSQKMVLSLSRL 424 LI +V + E HK+ AE+KAL AQ++PHFLYNTL+TI+WK +M+ SLSRL Sbjct: 372 NELINKVLKLEIHKKEAELKALEAQINPHFLYNTLDTIFWKAEKSHDSEISEMIYSLSRL 431 Query: 425 FQLGLNKGQEITTLSKELEHVRQYLELQSSCYEGLFHYEIHVREPELAALSIPRIILQPL 484 F+L LN+G E + E E + YL LQS Y+ Y I + +PE+ IP++ILQP Sbjct: 432 FRLTLNRGSEFIQVKGEKELIEHYLFLQSKRYKNRLQYSIEI-DPEILDYYIPKLILQPF 490 Query: 485 VENSILHGFRDLESGGRIEIEIAGDGERWVLAVRDNGSGMEE---DQVRALF--WQESEK 539 VEN+I+HG + + I+I +GE ++DNG GM + D+++ L +E+ Sbjct: 491 VENAIVHGMENSTTPTFIQITGKKEGENLCFTIKDNGIGMSKTQLDRIKDLLESGKEATF 550 Query: 540 GYAVSNLIRRLQLYYGDSAEFYVDSAAGRGTEVRISVP 577 GYA+ N+ RL+LYY + + S G+GTEV++ +P Sbjct: 551 GYAIKNVNERLKLYYETHFKLNIQSQPGQGTEVKLILP 588 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,236,126,580 Number of extensions: 133522717 Number of successful extensions: 359189 Number of sequences better than 1.0e-05: 1991 Number of HSP's gapped: 355618 Number of HSP's successfully gapped: 1991 Length of query: 582 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 441 Effective length of database: 1,732,333,088 Effective search space: 763958891808 Effective search space used: 763958891808 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)