BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0383.0007.p (302 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KDN9.1 B3KDN9_9BACI Aldo/keto reductase 384 e-105 C3BPK1.1 C3BPK1_9BACI Uncharacterized oxidoreductase yqkF 355 3e-96 C5D416.1 C5D416_9BACI Aldo/keto reductase 349 2e-94 A4IQJ7.1 A4IQJ7_GEOTN D-threo-aldose 1-dehydrogenase 348 5e-94 B4BLB0.1 B4BLB0_9BACI Aldo/keto reductase 348 5e-94 >B3KDN9.1 B3KDN9_9BACI Aldo/keto reductase Length = 301 Score = 384 bits (987), Expect = e-105, Method: Compositional matrix adjust. Identities = 194/302 (64%), Positives = 226/302 (74%), Gaps = 1/302 (0%) Query: 1 MKTNRLGNSDLYVSAMGLGCMSLGTDEARAAAIIHEALELGINFLDTADLYDEGRNEEII 60 MKTNRLG+S+LYVS +GLGCMSLGTDE +A +IHEAL+ G+NFLDTADLYD GRNEE++ Sbjct: 1 MKTNRLGSSELYVSEIGLGCMSLGTDEGQAVKLIHEALDQGVNFLDTADLYDAGRNEELV 60 Query: 61 GQALRGRRGDVILATKVGNRRIPGQAGWSWDPSKAYIKSAVKGSLRRLQTDYIDLYQLHG 120 G+A++GRR DVI+ATKVGNRR+PGQ GW WDPSK YIKSAVK SLRRL TDYIDLYQLHG Sbjct: 61 GKAIQGRREDVIIATKVGNRRVPGQEGWVWDPSKDYIKSAVKDSLRRLGTDYIDLYQLHG 120 Query: 121 GTLEDPIGETIEAFEELKQEGLIRYYGISSIRPNVIREYVSRSHIVSVMSQYSILDRRPE 180 GTL+DPI ETIEAFEELK+EG IRYYGISSIRPNVIREYV++SHIVSVMSQYSILDRRPE Sbjct: 121 GTLDDPIEETIEAFEELKREGWIRYYGISSIRPNVIREYVAKSHIVSVMSQYSILDRRPE 180 Query: 181 EAVLPLLEQHGIGLIARGPLAGGILTGHGGSKAHREYLGYSSXXXXXXXXXXXXQTGPSR 240 E VL LLE++GI IARGP+A GIL+ G +KA + YL YS G R Sbjct: 181 ETVLDLLEENGISAIARGPVARGILSDRGQAKAEKGYLDYSKQELLDVLKRLEA-FGRGR 239 Query: 241 TLTEAALHYPLANPAVAAVIPGASSXXXXXXXXXXXXXXXXXXXXXXXFRAASKSNRYAQ 300 L++ A+ Y LA+ AVA IPGASS +A S++N+Y Sbjct: 240 DLSQLAIRYALAHAAVACTIPGASSLEQLLHNLAAGDMEALSPQDIQSIQAISRANQYEA 299 Query: 301 HR 302 HR Sbjct: 300 HR 301 >C3BPK1.1 C3BPK1_9BACI Uncharacterized oxidoreductase yqkF Length = 304 Score = 355 bits (911), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 180/306 (58%), Positives = 214/306 (69%), Gaps = 6/306 (1%) Query: 1 MKTNRLGNSDLYVSAMGLGCMSLGTDEARAAAIIHEALELGINFLDTADLYDEGRNEEII 60 MK +LGNSDLYV+ MGLGCMSLGT+E A IIHEA++LGINF DTADLY+ G NEE + Sbjct: 1 MKKRQLGNSDLYVTEMGLGCMSLGTNEHEAIRIIHEAMDLGINFFDTADLYNYGLNEEFV 60 Query: 61 GQALRGRRGDVILATKVGNRRIPGQAGWSWDPSKAYIKSAVKGSLRRLQTDYIDLYQLHG 120 G+AL+G+R ++L TKVGNR I + GWSWDPSKAYIK+ VK SLRRLQTDYIDLYQLHG Sbjct: 61 GKALKGKRDQIVLTTKVGNRWIEEKNGWSWDPSKAYIKAEVKESLRRLQTDYIDLYQLHG 120 Query: 121 GTLEDPIGETIEAFEELKQEGLIRYYGISSIRPNVIREYVSRSHIVSVMSQYSILDRRPE 180 GT+EDPI ETIEAFEELKQEG+IR+YGISSIRPNVIREY RS+IVSV+ +YS+L+R+PE Sbjct: 121 GTIEDPIDETIEAFEELKQEGVIRHYGISSIRPNVIREYAKRSNIVSVLMEYSLLNRQPE 180 Query: 181 EAVLPLLEQHGIGLIARGPLAGGILTGHGGSK----AHREYLGYSSXXXXXXXXXXXXQT 236 E PLL++H I +IARGPLA G+LT + K ++YL YS T Sbjct: 181 EW-FPLLQEHQISIIARGPLAKGLLTDNNERKIEKVKEKDYLSYSYDELIKTLTTVKEIT 239 Query: 237 GPSRTLTEAALHYPLANPAVAAVIPGASSXXXXXXXXXXXXXXXXXXXXXXXFRAASKSN 296 R+LTE AL Y L +P VAAVIPGASS +AA K + Sbjct: 240 -KERSLTETALQYCLHDPIVAAVIPGASSIQQLQENVQANNQSPLTTEEYKQIQAAVKCD 298 Query: 297 RYAQHR 302 Y HR Sbjct: 299 TYTLHR 304 >C5D416.1 C5D416_9BACI Aldo/keto reductase Length = 306 Score = 349 bits (895), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 180/307 (58%), Positives = 209/307 (68%), Gaps = 6/307 (1%) Query: 1 MKTNRLGNSDLYVSAMGLGCMSLGTDEARAAAIIHEALELGINFLDTADLYDEGRNEEII 60 M+ R+G SDLYVS +GLGCMSLGTDE +A IIHEALE GIN+LDTADLYD G NEE + Sbjct: 1 MQKRRIGLSDLYVSEIGLGCMSLGTDEKKAIRIIHEALERGINYLDTADLYDRGLNEEFV 60 Query: 61 GQALRGRRGDVILATKVGNRRIPGQAGWSWDPSKAYIKSAVKGSLRRLQTDYIDLYQLHG 120 G+A++G+R VILATKVGNR G+ GW WDPSK YIKS VK SLRRLQTDYIDLYQLHG Sbjct: 61 GKAIKGKRDQVILATKVGNRWEDGKDGWFWDPSKKYIKSEVKESLRRLQTDYIDLYQLHG 120 Query: 121 GTLEDPIGETIEAFEELKQEGLIRYYGISSIRPNVIREYVSRSHIVSVMSQYSILDRRPE 180 GT++DPI ETIEAFEELKQEG+IRYYGISSIRPNVIREYV RS+IVSVM QYS+LDRRPE Sbjct: 121 GTIDDPIDETIEAFEELKQEGVIRYYGISSIRPNVIREYVKRSNIVSVMMQYSLLDRRPE 180 Query: 181 EAVLPLLEQHGIGLIARGPLAGGILT-----GHGGSKAHREYLGYSSXXXXXXXXXXXXQ 235 E PLL +H I +IARGP+A G+LT S YL Y+ + Sbjct: 181 EW-FPLLREHNISVIARGPVAKGLLTERPLEAASDSVKKNGYLDYTYEELQTLLPKLKAK 239 Query: 236 TGPSRTLTEAALHYPLANPAVAAVIPGASSXXXXXXXXXXXXXXXXXXXXXXXFRAASKS 295 T R+ T AL + L +P VAAVIPGASS + +K+ Sbjct: 240 TAEHRSFTATALQFCLYDPVVAAVIPGASSVEQLIENINAASAPRLTEEEYQWLQKHTKA 299 Query: 296 NRYAQHR 302 + Y HR Sbjct: 300 SVYKMHR 306 >A4IQJ7.1 A4IQJ7_GEOTN D-threo-aldose 1-dehydrogenase Length = 306 Score = 348 bits (892), Expect = 5e-94, Method: Compositional matrix adjust. Identities = 179/307 (58%), Positives = 209/307 (68%), Gaps = 6/307 (1%) Query: 1 MKTNRLGNSDLYVSAMGLGCMSLGTDEARAAAIIHEALELGINFLDTADLYDEGRNEEII 60 M R+G SDLYVS +GLGCMSLGTDE A +IHEAL+ GIN+LDTADLYD G NEE + Sbjct: 1 MNKRRIGTSDLYVSEIGLGCMSLGTDEREAIRLIHEALDRGINYLDTADLYDRGLNEEFV 60 Query: 61 GQALRGRRGDVILATKVGNRRIPGQAGWSWDPSKAYIKSAVKGSLRRLQTDYIDLYQLHG 120 G+A++G+R VI+ATKVGNR P +GW WDPSKAYIK AVK SLRRLQTDYIDLYQLHG Sbjct: 61 GKAVKGKRDQVIIATKVGNRWRPDGSGWDWDPSKAYIKQAVKDSLRRLQTDYIDLYQLHG 120 Query: 121 GTLEDPIGETIEAFEELKQEGLIRYYGISSIRPNVIREYVSRSHIVSVMSQYSILDRRPE 180 GT++DPI ETI AFEELKQEG+IR+YGISSIRPNVIREYV RS+IVSVM QYS+LDRRPE Sbjct: 121 GTIDDPIDETIAAFEELKQEGVIRWYGISSIRPNVIREYVKRSNIVSVMMQYSLLDRRPE 180 Query: 181 EAVLPLLEQHGIGLIARGPLAGGILTGH-----GGSKAHREYLGYSSXXXXXXXXXXXXQ 235 E PLL +H I +IARGP+A G+LT G + YL YS + Sbjct: 181 EW-FPLLREHNISVIARGPVAKGLLTDRPLEAAGAAVKEHGYLDYSYSELQALIPRLKEK 239 Query: 236 TGPSRTLTEAALHYPLANPAVAAVIPGASSXXXXXXXXXXXXXXXXXXXXXXXFRAASKS 295 TG R+LT AL + L +P VAAVIPGAS + A+K Sbjct: 240 TGERRSLTATALQFCLYDPVVAAVIPGASRLEQLAENIAAASALPLDADEYKWLKQATKR 299 Query: 296 NRYAQHR 302 + Y HR Sbjct: 300 SVYEMHR 306 >B4BLB0.1 B4BLB0_9BACI Aldo/keto reductase Length = 306 Score = 348 bits (892), Expect = 5e-94, Method: Compositional matrix adjust. Identities = 179/307 (58%), Positives = 209/307 (68%), Gaps = 6/307 (1%) Query: 1 MKTNRLGNSDLYVSAMGLGCMSLGTDEARAAAIIHEALELGINFLDTADLYDEGRNEEII 60 M R+G SDLYVS +GLGCMSLGTDE A +IHEAL+ GIN+LDTADLYD G NEE + Sbjct: 1 MNKRRIGTSDLYVSEIGLGCMSLGTDEREAIRLIHEALDRGINYLDTADLYDRGLNEEFV 60 Query: 61 GQALRGRRGDVILATKVGNRRIPGQAGWSWDPSKAYIKSAVKGSLRRLQTDYIDLYQLHG 120 G+A++G+R VI+ATKVGNR P +GW WDPSKAYIK AVK SLRRLQTDYIDLYQLHG Sbjct: 61 GKAVKGKRDQVIIATKVGNRWRPDGSGWDWDPSKAYIKQAVKDSLRRLQTDYIDLYQLHG 120 Query: 121 GTLEDPIGETIEAFEELKQEGLIRYYGISSIRPNVIREYVSRSHIVSVMSQYSILDRRPE 180 GT++DPI ETI AFEELKQEG+IR+YGISSIRPNVIREYV RS+IVSVM QYS+LDRRPE Sbjct: 121 GTIDDPIDETIAAFEELKQEGVIRWYGISSIRPNVIREYVKRSNIVSVMMQYSLLDRRPE 180 Query: 181 EAVLPLLEQHGIGLIARGPLAGGILTGH-----GGSKAHREYLGYSSXXXXXXXXXXXXQ 235 E PLL +H I +IARGP+A G+LT G + YL YS + Sbjct: 181 EW-FPLLREHNISVIARGPVAKGLLTDRPLEAAGAAVKEHGYLDYSYSELQALIPRLKEK 239 Query: 236 TGPSRTLTEAALHYPLANPAVAAVIPGASSXXXXXXXXXXXXXXXXXXXXXXXFRAASKS 295 TG R+LT AL + L +P VAAVIPGAS + A+K Sbjct: 240 TGERRSLTATALQFCLYDPVVAAVIPGASRLEQLAENIAAASALPLDADEYKWLKQATKR 299 Query: 296 NRYAQHR 302 + Y HR Sbjct: 300 SVYEMHR 306 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.135 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,594,758,966 Number of extensions: 63937296 Number of successful extensions: 179277 Number of sequences better than 1.0e-05: 7739 Number of HSP's gapped: 167357 Number of HSP's successfully gapped: 7750 Length of query: 302 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 167 Effective length of database: 1,788,859,178 Effective search space: 298739482726 Effective search space used: 298739482726 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 131 (55.1 bits)