BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0382.0032.p (2444 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C3HA39.1 C3HA39_BACTU Putative uncharacterized protein 2777 0.0 B6E113.1 B6E113_BACSU Bacillorin synthetase B 1776 0.0 B3TLA2.1 B3TLA2_BACSU Iturin A synthetase B 1757 0.0 C3HA00.1 C3HA00_BACTU Phenylalanine racemase 1751 0.0 B3TLA3.1 B3TLA3_BACSU Iturin A synthetase C 1745 0.0 >C3HA39.1 C3HA39_BACTU Putative uncharacterized protein Length = 2232 Score = 2777 bits (7199), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1322/2230 (59%), Positives = 1711/2230 (76%), Gaps = 6/2230 (0%) Query: 207 LIIAILGTLKAGGAYLPIDPEYPADRINYMLTDSQAAMLLFQHHIVKDLTYAGGRLELEN 266 +I+ ILG LKAGGAYLPIDPEYP DRI+YML DS A++LL + + KD+ Y+G + L+N Sbjct: 1 MIVGILGILKAGGAYLPIDPEYPNDRISYMLGDSGASILLVKDQLAKDIKYSGKVINLKN 60 Query: 267 SELYIRETGNPVKASLPENLAYVIYTSGTTGTPKGVMVEHRNLVNYIHWANKRYVAGEQT 326 LY +E N + ++ P LAYVIYTSGTTG PKGVMV+H+ +VNYI+WA K YV Sbjct: 61 YSLYEQEKSNLMNSNQPHQLAYVIYTSGTTGAPKGVMVKHKGVVNYIYWAKKSYVDNGTF 120 Query: 327 AFPLYSSISFDLTVTSIYTPLISGNTIVIYDGEDKALLTRTIAEENKVNIVKLTPTHLRL 386 FPLYSSI+FDLTVTS+Y PLI+GN IVIY+G DKALL R I EENK++I+KLTPTHLRL Sbjct: 121 NFPLYSSIAFDLTVTSLYIPLITGNKIVIYEGGDKALLIRRIIEENKIDIIKLTPTHLRL 180 Query: 387 LEDMDLSRSSIRTFIVGGEDLKIKVAEKIHRAFDGRIEIYNEYGPTEATVGCMIYKYNAE 446 LE+MDLS+S I+ IVGGE+LK++ AEK++RAF+G I+IYNEYGPTEATVGCMIYKYNAE Sbjct: 181 LENMDLSKSKIKKLIVGGEELKVEQAEKVYRAFNGSIDIYNEYGPTEATVGCMIYKYNAE 240 Query: 447 RDKGTSVSIGIPADNTQLYIVGSRMELLPVGVAGELCIGGDGVARGYLHKEALTAEKFVD 506 +DKG SVSIG+PA NT+LY++G MELLP+GVAGELC+ GDG+A GY+++E LTA KFV+ Sbjct: 241 KDKGISVSIGVPAGNTKLYVLGKNMELLPIGVAGELCVSGDGLASGYINREELTAMKFVE 300 Query: 507 HPFNAGSKLYKTGDMARWLSDGTVEYLGRMDNQVKIRGYRIETGEIENRLLQMPDITEAV 566 +PF +K+YKTGD+ +W+ DG VEYLGR+DNQVKIRGYRIE GEIENRLL++ D+ EAV Sbjct: 301 NPFEPNNKMYKTGDLVKWMPDGNVEYLGRIDNQVKIRGYRIEIGEIENRLLKIKDVKEAV 360 Query: 567 VVARTDEQGHNYLCAYVVSNKEVIASEVKGRLSKELPNYMVPGFTVQIAKLPLSSNGKVD 626 V+A+ D+ + +LC+Y+ SNK+V S++K +L +ELP YMVP + +QI K+PLSSNGK+D Sbjct: 361 VIAKKDQNENVFLCSYITSNKKVRISKIKEKLIRELPMYMVPSYIIQIDKIPLSSNGKID 420 Query: 627 IKALPAVDISEMLAASYEAPNNKVEEILVDVWQRVLNIEPIGTNYNYYEMGGDSIKSILI 686 ALP +D++E++ + YE P +K+EEILV VW+++L I+ IG NYNYYE+GGDSIKSILI Sbjct: 421 TMALPVIDVTELIESKYEEPRDKIEEILVKVWEKILGIDRIGINYNYYEIGGDSIKSILI 480 Query: 687 VSALREHGLRLEVKDLMQYPSIKELAGYVKHEDVQAPQEAVEGSVPFLPVQQWFFEQGLP 746 VS LR++ LRLE+KDLMQ+P IKEL +VK +D Q Q AVEG +P+Q+WF EQ Sbjct: 481 VSELRKYHLRLEIKDLMQFPRIKELREHVKLDDTQVNQSAVEGKADLVPIQKWFIEQEFS 540 Query: 747 QENHYNQAFMFYRKEGLDEEILRKAVVAILVHHDALRMVYKRTPDGITQWNRSADCAGAA 806 QENHYNQAFMFY+++G+DE++LRK + I+ HHDALRM+Y + + QWNR + A A Sbjct: 541 QENHYNQAFMFYKQDGIDEKVLRKVFLEIVKHHDALRMMYIKENNEFKQWNRGIEQAEEA 600 Query: 807 FTLDVYDLRGQDE-KRSIPALSDELQKGLDLEEGLLVKLGLFKTSLGDHLLVAVHHLVID 865 F+L++YDLR ++ +R+I LS E+QKG+ LE+G+L+KLGLFKT +GDHLLVA+HH+VID Sbjct: 601 FSLNLYDLREEENPERNIEMLSSEIQKGMSLEDGILIKLGLFKTKIGDHLLVAIHHIVID 660 Query: 866 GVSWRILIADLETAYRNIAAGAAASLPPKTASYRSWAQKLKEYASGKVLLKEAEYWKGIT 925 G+SWRIL+ DLET Y I LP KT S++ WAQKL E+A GK + KE +WK I Sbjct: 661 GLSWRILLEDLETLYLKIENEEEVKLPQKTTSFKEWAQKLNEFAKGKEIQKELVFWKKID 720 Query: 926 NTGSGPLPKDFGEENRGCGERMEVSLNFSKEQTAKLLRNCNTAYNTQINDVLLCSLGLAF 985 T LPKDF E + E E+S++F++EQT KLLR N AYNT IND+LLCSLGLA Sbjct: 721 ETPFETLPKDFSECDILSKEGEEISISFTREQTEKLLRKTNAAYNTHINDILLCSLGLAV 780 Query: 986 KEWGGMDQLLVSLEGHGREEIFQGVSIDRTIGWFTTIFPVVLDMTRSHDLAYSLKRTKEM 1045 +W G+D++ VSLEGHGRE+I + +SI+RTIGWFT+++PV LDM+ S +L+YS+K TKE+ Sbjct: 781 NKWCGIDKVCVSLEGHGREDILKDISINRTIGWFTSLYPVTLDMSYSDNLSYSIKLTKEI 840 Query: 1046 LRHVPHKGIGYGIWKYLADGNKELR-AFEPEVSFNYLGEFGREAGSSLLEFSRLSSGASI 1104 LRH+P+KGIGYGI KYL++ K +PE+SFNYLGEFG+E L +S + +G SI Sbjct: 841 LRHIPNKGIGYGILKYLSNVEKGSHFKLKPEISFNYLGEFGQEESEGLFRYSNIPTGISI 900 Query: 1105 SIDNNKLKGIDINGLIMEGELELVFSYSTLEYTRETVAQLTAAYHTSLLQVIDHCAHRQT 1164 S +N KL I+INGL++EG+L +F+Y+ EY R+T+ + Y SL +VIDHC +++ Sbjct: 901 SRENKKLHSIEINGLVIEGQLRFIFNYNAKEYKRKTIEKFANIYKKSLSEVIDHCENKKV 960 Query: 1165 AEKTPWDYGDPDLSLEDLDTLLACGQEIEKIHSLSPMQEGMMYNTIVDAGSSTYFEQSEL 1224 AEKTPWDYGDPDL LEDL + ACG+EIEKIHSLSPMQEGM+YN+I++ SS Y EQSEL Sbjct: 961 AEKTPWDYGDPDLDLEDLKKITACGKEIEKIHSLSPMQEGMLYNSIIENDSSAYLEQSEL 1020 Query: 1225 NIEGYLNVEILNMVLNELTGKYEILRTAFFYHDIKKFKQAVLKERKLRIHYEDISSRSMQ 1284 +EG ++VEILN +LN++ KYEILRT FFY +I FKQAVL++RK++IHYEDIS ++ Sbjct: 1021 TVEGTIDVEILNSILNKIIEKYEILRTVFFYENISLFKQAVLRKRKIKIHYEDISHWDIE 1080 Query: 1285 EQSSYIEQFKVQDRSNPFDLEQDCLLRVAVLKTDTGNFKVVYSFHHIIMDGWSAGIILQE 1344 + +YIE FK++DR N F L +D L+RV+V+K FK++YSFHHIIMDGWS GIIL+E Sbjct: 1081 TKENYIEHFKIRDRDNRFQLTKDVLIRVSVIKVQNNIFKIIYSFHHIIMDGWSIGIILKE 1140 Query: 1345 VIAQYKARLQEAELKQEKAVPYSDYLDWLDHQDKAAALDYWQSYLEAYESGTVIPELQHQ 1404 ++ YKA ++ EL EK V YS YL WLD +DK AL+YW++YL AYE V PE Q + Sbjct: 1141 IMDNYKAAVKGRELPIEKTVSYSRYLKWLDQKDKLVALEYWENYLHAYEQEIVFPEQQLK 1200 Query: 1405 EKGFMHQQERTSLDAQATAKLKSLAEANGITLSSVIQTAWGVVLQKYSNTHDVVFGSVVS 1464 + +QER SL TAKLK+LAEAN ITLSS+IQTAWGV+LQKY+NT+DVVFGSVVS Sbjct: 1201 VDKYKRRQERISLTENITAKLKNLAEANSITLSSIIQTAWGVLLQKYNNTNDVVFGSVVS 1260 Query: 1465 GRPSDIKGIERMVGLCINTVPVRVTGGDQLSFIALAKKLNKDFIHANAFSFCQLAEIQAL 1524 GR S+I GIE MVGL INTVP+RV D SFI LAKK+NKDFI AN +S+C LAE+Q L Sbjct: 1261 GRSSEIDGIENMVGLFINTVPIRVRTKDTTSFIELAKKINKDFIEANTYSYCSLAEVQTL 1320 Query: 1525 SPMKNNLINHVVVYENYPVDQSLADLQEAEGREVKITAAQGFEQTNYDLEILIAPGRTLQ 1584 + MKN LINHVV+YENYP+D +LA E+KIT GFEQTNYDLE+LI PG L Sbjct: 1321 TNMKNKLINHVVIYENYPLDMNLASFHSDYESELKITDTSGFEQTNYDLELLIIPGNELN 1380 Query: 1585 IKITYNGCKYSRDVINALMDNLMHVLSCAVSNPDQAAESIDMVSEQERNKLLYELNCTGT 1644 +KITYN YS+DVI+A++ NL+++L + + IDMVS ERNKLL E N T Sbjct: 1381 MKITYNNNIYSKDVISAILYNLINILKNLSFDWEVKVSDIDMVSGVERNKLLREFNDTEV 1440 Query: 1645 AYAKEKTIAQLFEEQAERTPEAIALEFHGTVLSYRELNKRANQLARVLRRNSVGANVIVP 1704 Y+KEKTI +LFEEQ ERTP A+ALEF+G L+Y ELNK+AN+LAR+LRRN V N +VP Sbjct: 1441 IYSKEKTIQELFEEQVERTPTAVALEFNGEPLTYNELNKKANKLARILRRNYVKENTVVP 1500 Query: 1705 ILVKRSLNLLVGILGILKAGGGYLPLDTDYPVDRIHYMLQDSQASLLLTEKGLAAPLGLN 1764 IL++RS NL+VGILGILKAGG YLPLD +YPVDRI YML+DS+ +LLLTE L+ L Sbjct: 1501 ILIRRSCNLIVGILGILKAGGCYLPLDPEYPVDRIDYMLEDSKGNLLLTEGNLSKHLSFT 1560 Query: 1765 EAVTILDIGSKQIQDEDDSNLQSITKADDLAYVLYTSGSTGNPKGVAVEQRGVHNFIKGI 1824 I++I S++++ + DSN+ I A+DLAYV+YTSGSTG PKGVA+E R HNFIKGI Sbjct: 1561 GP--IINIDSQELEHQMDSNIGKINAAEDLAYVIYTSGSTGKPKGVAIEHRAFHNFIKGI 1618 Query: 1825 TDRISFTEDKIILSVTTCSFDIFGLESLLPLTRGLKVVIASEEEQKDPHLLNKVILDSEV 1884 T+RI FT + +ILSVTTCSFDIFGLE++LPL +GLKVVIA+E EQKDP+LLNKVI++SEV Sbjct: 1619 TERIDFTYNNVILSVTTCSFDIFGLETILPLIKGLKVVIANEMEQKDPYLLNKVIINSEV 1678 Query: 1885 NTIQLTPSRLKLMLNCSNTAESFKKLKLMMIGGEGFPKDLLVQLQKFTDSRIYNMYGPTE 1944 NTIQLTPSRLKLMLN SN+ E F+KL L+M+GGE FP DLL QL+++T+S+IYNMYGPTE Sbjct: 1679 NTIQLTPSRLKLMLNSSNSKECFQKLNLIMVGGEAFPDDLLYQLKEYTNSKIYNMYGPTE 1738 Query: 1945 TTIWSTVKELTHENSVNVGKPIANTQVYIVDQAGHLAPIGVAGELCIAGDGVARGYLHKE 2004 TTIWST+K+LT ENS+N+GKPIANT VYI+D G+ PIG GELCIAGDG+ARGYL++E Sbjct: 1739 TTIWSTIKDLTKENSINIGKPIANTHVYIIDDVGNTVPIGSVGELCIAGDGLARGYLNRE 1798 Query: 2005 ELTASKFVDNPFMQGTKMYTTGDLARWLPNGELDVIGRLDNQVKIGGYRIELGEIESVAA 2064 ELT +FV NPF+ KMY TGDLA+WLP GE+D++GR+D+QVKI GYRIELGEIE VA Sbjct: 1799 ELTVKRFVKNPFVNIGKMYKTGDLAKWLPGGEIDIVGRMDDQVKIRGYRIELGEIEIVAN 1858 Query: 2065 RHDKITQCVVAGQPNSLGSQDLVLYFVAAEKISTSELVNFLSPVLPKYMMPQMYIQIDEI 2124 ++ KI +C+ G+ NS G Q+LVLY+VA EKI+TSEL+ +LS +LP YM+PQ+Y++IDEI Sbjct: 1859 QYGKIKECIAVGKTNSFGEQELVLYYVAEEKINTSELIKYLSSMLPTYMIPQIYMEIDEI 1918 Query: 2125 PLTANGKTNLKALPKPGNVRPELRDDYEEAVTDLQKEIQQVWSLILNIEQVGIYDNFFEV 2184 PLT NGK N KALP+P RP+L DYEE VTD+Q+ I+ +W+ IL IE++GI+DNFFE Sbjct: 1919 PLTTNGKLNRKALPEPTQNRPQLNSDYEEVVTDVQRNIRDIWNSILGIEKIGIHDNFFEA 1978 Query: 2185 GGNSLKIVAMYNELQKLYPGKIQITDIFSYPTISRLAQFIDNQSAFAEAAVALDHEGMAI 2244 GGNS+KIVAM+NE++KLYP KIQITDIF++PTI RLAQFI++ F E + + + M I Sbjct: 1979 GGNSIKIVAMHNEIKKLYPKKIQITDIFAHPTIYRLAQFIESIEKFEELSTPVAQDIMPI 2038 Query: 2245 ELPAVYLAGEAEPDDGRVLRFSFAGDSYAGLVQACTRNRYEIIHLLLAGYVFLLSDICQR 2304 ELP Y E ++ +L+F Y+GL+ C N YEI HLLLA YVFLL+D C + Sbjct: 2039 ELPLEYFWLEDYLNEEPLLKFKLTEYEYSGLLGICGDN-YEIYHLLLACYVFLLADTCGK 2097 Query: 2305 ERLAVQFSDQAAGRFGWIEADITGLDNFYEIVSLVKDQHKHLLESPRYTVQSDLEMFRTG 2364 + +Q +Q + + DI+ ++NFY+I+ ++KD+ + + +S +Y++ S E+F + Sbjct: 2098 NLVTIQLDNQGEEQISQLSVDISDIENFYDIIRIIKDKIESVKKSQQYSINSLSEVFDSV 2157 Query: 2365 SGSTVVPLFSRVNDSHPAADHEDDDLVLEAAEKAGEIEIVWRYNRSKLKQAKMYELFNQY 2424 + PLF RV+++ DLV E E E+EI+ YN KL Q+K+ +LF +Y Sbjct: 2158 IDHCIFPLF-RVSNNPNVNYLRFYDLVFEIYEGHSEVEIICTYNDQKLNQSKIKDLFYKY 2216 Query: 2425 IKLLQVIIES 2434 I+L++ I +S Sbjct: 2217 IELIRAITKS 2226 Score = 455 bits (1171), Expect = e-125, Method: Compositional matrix adjust. Identities = 269/741 (36%), Positives = 429/741 (57%), Gaps = 28/741 (3%) Query: 26 RNPLFDVMFVLEN--LDYGLGP--NEEQAKVKLIEPMA-EVAKFDLTLTAKEAGGNLDFS 80 +N L + + + EN LD L ++ ++++K+ + E +DL L G L+ Sbjct: 1324 KNKLINHVVIYENYPLDMNLASFHSDYESELKITDTSGFEQTNYDLELLII-PGNELNMK 1382 Query: 81 LEYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGGLDMLSNQEKHLLLNVFKGTPTDY 140 + Y++ +++K + + + +L + + + ++ +DM+S E++ LL F T Y Sbjct: 1383 ITYNNNIYSKDVISAILYNLINILKNLSFDWEVKVSDIDMVSGVERNKLLREFNDTEVIY 1442 Query: 141 PKDKTIHELFEEQADRTPDQLAVVCGGQALTYSELNEQANSLASVLREKGVGAEAIVGIM 200 K+KTI ELFEEQ +RTP +A+ G+ LTY+ELN++AN LA +LR V +V I+ Sbjct: 1443 SKEKTIQELFEEQVERTPTAVALEFNGEPLTYNELNKKANKLARILRRNYVKENTVVPIL 1502 Query: 201 ADRSLELIIAILGTLKAGGAYLPIDPEYPADRINYMLTDSQAAMLLFQHHIVKDLTYAGG 260 RS LI+ ILG LKAGG YLP+DPEYP DRI+YML DS+ +LL + ++ K L++ G Sbjct: 1503 IRRSCNLIVGILGILKAGGCYLPLDPEYPVDRIDYMLEDSKGNLLLTEGNLSKHLSFTGP 1562 Query: 261 RLELENSELYIRETGNPVKASLPENLAYVIYTSGTTGTPKGVMVEHRNLVNYIHWANKRY 320 + +++ EL + N K + E+LAYVIYTSG+TG PKGV +EHR N+I +R Sbjct: 1563 IINIDSQELEHQMDSNIGKINAAEDLAYVIYTSGSTGKPKGVAIEHRAFHNFIKGITERI 1622 Query: 321 VAGEQTAFPLYSSISFDLTVTSIYTPLISGNTIVI---YDGEDKALLTRTIAEENKVNIV 377 ++ SFD+ PLI G +VI + +D LL + I ++VN + Sbjct: 1623 DFTYNNVILSVTTCSFDIFGLETILPLIKGLKVVIANEMEQKDPYLLNKVII-NSEVNTI 1681 Query: 378 KLTPTHLRLLEDMDLSRSSIRTF---IVGGEDLKIKVAEKIHRAFDGRIEIYNEYGPTEA 434 +LTP+ L+L+ + S+ + +VGGE + ++ + + IYN YGPTE Sbjct: 1682 QLTPSRLKLMLNSSNSKECFQKLNLIMVGGEAFPDDLLYQLKEYTNSK--IYNMYGPTET 1739 Query: 435 TVGCMIYKYNAERDKGTSVSIGIPADNTQLYIVGSRMELLPVGVAGELCIGGDGVARGYL 494 T+ I + K S++IG P NT +YI+ +P+G GELCI GDG+ARGYL Sbjct: 1740 TIWSTI----KDLTKENSINIGKPIANTHVYIIDDVGNTVPIGSVGELCIAGDGLARGYL 1795 Query: 495 HKEALTAEKFVDHPFNAGSKLYKTGDMARWLSDGTVEYLGRMDNQVKIRGYRIETGEIEN 554 ++E LT ++FV +PF K+YKTGD+A+WL G ++ +GRMD+QVKIRGYRIE GEIE Sbjct: 1796 NREELTVKRFVKNPFVNIGKMYKTGDLAKWLPGGEIDIVGRMDDQVKIRGYRIELGEIEI 1855 Query: 555 RLLQMPDITEAVVVARTDEQGHNYLCAYVVSNKEVIASEVKGRLSKELPNYMVPGFTVQI 614 Q I E + V +T+ G L Y V+ +++ SE+ LS LP YM+P ++I Sbjct: 1856 VANQYGKIKECIAVGKTNSFGEQELVLYYVAEEKINTSELIKYLSSMLPTYMIPQIYMEI 1915 Query: 615 AKLPLSSNGKVDIKALP-AVDISEMLAASYEAPNNKVEEILVDVWQRVLNIEPIGTNYNY 673 ++PL++NGK++ KALP L + YE V+ + D+W +L IE IG + N+ Sbjct: 1916 DEIPLTTNGKLNRKALPEPTQNRPQLNSDYEEVVTDVQRNIRDIWNSILGIEKIGIHDNF 1975 Query: 674 YEMGGDSIKSILIVSALRE-HGLRLEVKDLMQYPSIKELAGYV----KHEDVQAPQEAVE 728 +E GG+SIK + + + +++ + ++++ D+ +P+I LA ++ K E++ P + Sbjct: 1976 FEAGGNSIKIVAMHNEIKKLYPKKIQITDIFAHPTIYRLAQFIESIEKFEELSTP--VAQ 2033 Query: 729 GSVPF-LPVQQWFFEQGLPQE 748 +P LP++ ++ E L +E Sbjct: 2034 DIMPIELPLEYFWLEDYLNEE 2054 >B6E113.1 B6E113_BACSU Bacillorin synthetase B Length = 5384 Score = 1776 bits (4599), Expect = 0.0, Method: Compositional matrix adjust. Identities = 920/2286 (40%), Positives = 1396/2286 (61%), Gaps = 44/2286 (1%) Query: 58 MAEVAKFDLTLTAKEAGGNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGG 117 M E +D LT G ++ S EY++ ++++A+++R+ EH+ ++L + + D + Sbjct: 1700 MEEQTNYDFNLTVI-PGDEMNISFEYNANVYDRASIERVREHFMQILHQVVTDADIRVDQ 1758 Query: 118 LDMLSNQEKHLLLNVFKGTPTDYPKDKTIHELFEEQADRTPDQLAVVCGGQALTYSELNE 177 ++L+ E+ LL T +P+ +H+LFEEQ++RTPDQ AV+ + LTY ELN+ Sbjct: 1759 AELLTEGERRTLLQTLNDTAAPFPQ-TPVHQLFEEQSERTPDQAAVIDKDRQLTYGELNK 1817 Query: 178 QANSLASVLREKGVGAEAIVGIMADRSLELIIAILGTLKAGGAYLPIDPEYPADRINYML 237 +AN LA LR KGV + V I+ S+E ++ IL LK+GGAY+PIDPEYP DRI YML Sbjct: 1818 RANRLARTLRAKGVQTDQPVAIITRNSIESVVGILAVLKSGGAYVPIDPEYPQDRIRYML 1877 Query: 238 TDSQAAMLLFQHHIVKDLTYAGGRLELENSELYIRETGNPVKASLPENLAYVIYTSGTTG 297 DSQA ++L Q + K L Y G + L++ Y ++ + + +LAYVIYTSG+TG Sbjct: 1878 DDSQAGIVLMQRDVRKQLAYEGVTVLLDDESSYHQDGSDLAPINDVSHLAYVIYTSGSTG 1937 Query: 298 TPKGVMVEHRNLVNYIHWANKRYVAGEQTAFPLYSSISFDLTVTSIYTPLISGNTIVIYD 357 PKGV++EH L NYI WA K YV GE+ FPLY SISFDLTVTS +TPL++GN I++YD Sbjct: 1938 RPKGVLIEHGGLTNYIWWAKKVYVKGEKANFPLYPSISFDLTVTSNFTPLVTGNAIIVYD 1997 Query: 358 GEDKALLTRTIAEENKVNIVKLTPTHLRLLEDMDLS-RSSIRTFIVGGEDLKIKVAEKIH 416 GEDK L +I + +V+I+KLTP HL++L++M+++ ++++R IVGGE+L ++A IH Sbjct: 1998 GEDKTALLESIVRDPRVDIIKLTPAHLQVLKEMNIADQTAVRRMIVGGENLSTRLARSIH 2057 Query: 417 RAFDGRIEIYNEYGPTEATVGCMIYKYNAERDKGTSVSIGIPADNTQLYIVGSRMELLPV 476 FDGRIEI NEYGPTE VGCMIY+Y+A +D+ SV IG A NT +Y++ M+ P+ Sbjct: 2058 EQFDGRIEICNEYGPTETVVGCMIYRYDAAKDRRESVPIGTAAANTSIYVLDENMKPAPI 2117 Query: 477 GVAGELCIGGDGVARGYLHKEALTAEKFVDHPFNAGSKLYKTGDMARWLSDGTVEYLGRM 536 GV GE+ I G GVARGYL++ LTAEKFVD PF G+K+YKTGD+A+WL+DG +EY GR+ Sbjct: 2118 GVPGEIYISGAGVARGYLNRPELTAEKFVDDPFEPGAKMYKTGDLAKWLADGNIEYAGRI 2177 Query: 537 DNQVKIRGYRIETGEIENRLLQMPDITEAVVVARTDEQGHNYLCAYVVSNKEVIASEVKG 596 D QVKIRGYRIE GEIE LLQ I EAVV AR D G LCAY VS + A+ ++ Sbjct: 2178 DEQVKIRGYRIELGEIEAALLQEEVIKEAVVTAREDVHGFKQLCAYYVSGGQTTAARLRK 2237 Query: 597 RLSKELPNYMVPGFTVQIAKLPLSSNGKVDIKALPAVDISEMLAASYEAPNNKVEEILVD 656 +LS+ L +YMVP + +++ ++PL+SNGK++ K LPA D A Y+AP K EEILV Sbjct: 2238 QLSQTLASYMVPAYFIELDEMPLTSNGKINKKGLPAPDFELQDRAEYKAPRTKAEEILVS 2297 Query: 657 VWQRVLNIEPIGTNYNYYEMGGDSIKSILIVSALREHGLRLEVKDLMQYPSIKELAGYVK 716 W+ VL E + N++++GGDSIKSI + S L + G ++E+KDL QY +I EL+ ++K Sbjct: 2298 AWESVLGAENVSILDNFFDLGGDSIKSIQVSSRLNQQGYKMEIKDLFQYATIAELSPHIK 2357 Query: 717 HEDVQAPQEAVEGSVPFLPVQQWFFEQGLPQENHYNQAFMFYRKEGLDEEILRKAVVAIL 776 A Q V+G V P+Q WFFEQ +++YNQA M + EG E LR+ + + Sbjct: 2358 QNLRIADQGEVKGKVSLTPIQHWFFEQTTTDQHYYNQAVMLHAPEGFQETQLRQTLQKLA 2417 Query: 777 VHHDALRMVYKRTPDGITQWNRSADCAGAAFTLDVYDLR-GQDEKRSIPALSDELQKGLD 835 HHDALRM ++ T +G N +G + L+V +L+ D R+I A +DE+Q + Sbjct: 2418 EHHDALRMTFRTTENGCEAQNEEIAQSG-LYRLEVLNLKEDPDPGRTIEAKADEIQSSMH 2476 Query: 836 LEEGLLVKLGLFKTSLGDHLLVAVHHLVIDGVSWRILIADLETAYRNIAAGAAASLPPKT 895 L +G L+K GLF+ + GDHLL+A+HHL+IDG+SWRIL+ D+ + Y+ G LP KT Sbjct: 2477 LSDGPLMKAGLFQCADGDHLLIAIHHLIIDGISWRILLEDIVSGYKQAENGRVIQLPQKT 2536 Query: 896 ASYRSWAQKLKEYASGKVLLKEAEYWKGITNTGSGPLPKDFGEENRGCGERMEVSLNFSK 955 S++ WA++L EYA + + +E EYW I T PLPKDF E + + ++ ++K Sbjct: 2537 DSFQLWAKRLSEYAQSETIKQEQEYWTKIEQTEVKPLPKDFHETHTTAKDSETATVEWTK 2596 Query: 956 EQTAKLLRNCNTAYNTQINDVLLCSLGLAFKEWGGMDQLLVSLEGHGREEIFQGVSIDRT 1015 E+T LL+ N AY+T+IND+LL SLGL+ W G++Q+ + LEGHGRE+I Q + I RT Sbjct: 2597 EETELLLKQANRAYHTEINDLLLTSLGLSISHWSGLEQIPIHLEGHGREQIIQDIDISRT 2656 Query: 1016 IGWFTTIFPVVLDMTRSHDLAYSLKRTKEMLRHVPHKGIGYGIWKYLADGNKELRAFEPE 1075 +GWFT+++PVVL +++ +K TKE LR +P+KGIGYGI +YL+ G PE Sbjct: 2657 VGWFTSLYPVVLHAQPGKEISDYIKTTKEGLRQIPYKGIGYGIARYLSGGMPS--KLNPE 2714 Query: 1076 VSFNYLGEFGREAGSSLLEFSRLSSGASISIDNNKLKGIDINGLIMEGELELVFSYSTLE 1135 +SFNYLG+F ++ ++ S S G+ S + + ++ING+I EG L+L SYS+ + Sbjct: 2715 ISFNYLGQFDQDLQQHGVQLSSYSCGSDSSGNQERPYVLNINGMITEGRLKLTISYSSKQ 2774 Query: 1136 YTRETVAQLTAAYHTSLLQVIDHCAHRQTAEKTPWDYGDPDLSLEDLDTL---LACGQEI 1192 Y +ET+ +L+ + L +I HC H++ +E TP D +S+++LD L L E+ Sbjct: 2775 YAKETIMRLSETIQSRLRTIITHCVHKEQSELTPSDILLKGISIDELDQLLIQLPHAGEV 2834 Query: 1193 EKIHSLSPMQEGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEILRTA 1252 E ++ L+PMQ+GM++++++D SS+YFEQ+ +++G L ++ L L Y +LRT Sbjct: 2835 ENVYPLTPMQKGMLFHSLLDEASSSYFEQASFDLQGELKIDWFKASLERLFETYAVLRTR 2894 Query: 1253 FFYHDIKKFKQAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDRSNPFDLEQDCLLRV 1312 F+ Q V K + +IH+ D+ + I ++ +D++ FDL +D L+R+ Sbjct: 2895 FYSGWNDTPLQIVYKTQTPQIHFADLRDIEEHLREDAIAAYQREDKAKGFDLARDPLMRI 2954 Query: 1313 AVLKTDTGNFKVVYSFHHIIMDGWSAGIILQEVIAQYKARLQEAELKQEKAVPYSDYLDW 1372 A+ + + + +++SFHHI+MDGW +I +EV Y A + E + A PYSDY++W Sbjct: 2955 AIFRMEDRKYHLIWSFHHIVMDGWCLSLITKEVFDHYSALQEGREPEPPSAAPYSDYIEW 3014 Query: 1373 LDHQDKAAALDYWQSYLEAYESGTVIPE--LQHQEKGFMHQQERTSLDAQATAKLKSLAE 1430 LD QD+ AA YW YLE Y+ T + QH++K + + D + T +L+ +A Sbjct: 3015 LDRQDQGAAKRYWSGYLEGYKGETTLLHKIAQHEQKEYAYANVICRFDHEQTKQLQQIAN 3074 Query: 1431 ANGITLSSVIQTAWGVVLQKYSNTHDVVFGSVVSGRPSDIKGIERMVGLCINTVPVRVTG 1490 + +TL+++IQT WG++LQKYS + DVVFGSVVSGRP++I +E+M+GL INT+PVR+ Sbjct: 3075 QHQVTLNTLIQTLWGILLQKYSGSADVVFGSVVSGRPAEIPDVEQMIGLFINTIPVRIRC 3134 Query: 1491 GDQLSFIALAKKLNKDFIHANAFSFCQLAEIQALSPMKNNLINHVVVYENYPVDQSLADL 1550 + +F + + ++ + + ++ L EIQA + K NLI+H++++ENYP+ Q + + Sbjct: 3135 DEDSTFADTMQMVQQNALASQSYDTYPLYEIQAQTEQKQNLIDHIMIFENYPIGQQVEEG 3194 Query: 1551 QEAEGREVKITAAQGFEQTNYDLEILIAPGRTLQIKITYNGCKYSRDVINALMDNLMHVL 1610 +A ++ I E T+YD +++ PG L + ++N +Y + + + ++ Sbjct: 3195 HDAA--DLNIVNFHIEEHTHYDFNVVVIPGEQLTVHFSFNRNEYEQSEAERIRGHFEQLM 3252 Query: 1611 SCAVSNPDQAAESIDMVSEQERNKLLYELNCTGTAYAKEKTIAQLFEEQAERTPEAIALE 1670 + P E ++++++QE+ +L Y +E+TI QLFEEQA RTP+ A+ Sbjct: 3253 QQVLQLPSVKVEEMELLTQQEKEQLHSRFQSNEMHYPREQTIHQLFEEQALRTPDHEAVI 3312 Query: 1671 FHGTVLSYRELNKRANQLARVLRRNSVGANVIVPILVKRSLNLLVGILGILKAGGGYLPL 1730 F ++Y ELN+RANQLAR LR + A+ +V I+ +RSL ++VGI ILKAGG Y+P+ Sbjct: 3313 FEEQRMTYLELNERANQLARTLRAEGLQADQLVAIMAERSLEMMVGIYAILKAGGAYVPI 3372 Query: 1731 DTDYPVDRIHYMLQDSQASLLLTEKGLAAPLGLNEAVTILDIGSKQIQDEDDSNLQSITK 1790 D DYP +RI Y+L+DS A+LLL+++ + + A T++D+ + D+D SNL ++ Sbjct: 3373 DPDYPEERIRYILEDSGATLLLSQRHVKERVAF--AGTVIDLDDTSVYDDDVSNLDPLSG 3430 Query: 1791 ADDLAYVLYTSGSTGNPKGVAVEQRGVHNFIKGITDRISFTEDKIILSVTTCSFDIFGLE 1850 A D AYV+YTSGSTG PKGV VE R V N + + IL T +FD+ E Sbjct: 3431 AGDRAYVIYTSGSTGKPKGVMVEHRPVINRLMWMQKAYPIGSGDTILQKTAITFDVSVWE 3490 Query: 1851 SLLPLTRGLKVVIASEEEQKDPHLLNKVILDSEVNTIQLTPSRLKLMLNCSNT------A 1904 G KV + +KDP ++ I + + T+ P+ L L + T Sbjct: 3491 LFWWALTGAKVCLLPLGGEKDPEVIWNTIEEQSITTMHFVPAMLHAFLKFAETQTASGQT 3550 Query: 1905 ESFKKLKLMMIGGEGFPKDLLVQLQKF----TDSRIYNMYGPTETTI---WSTVKELTHE 1957 + L+ + GE + + +++ N+YGPTE T+ + + Sbjct: 3551 SKLRTLRQVFASGEALMPAHTARFHRLITPVNGAQLINLYGPTEATVDVSYFNCEANQAY 3610 Query: 1958 NSVNVGKPIANTQVYIVDQAG-HLAPIGVAGELCIAGDGVARGYLHKEELTASKFVDNPF 2016 SV +GKPI+N Q+Y++ L P+GV GELCIAGDG+ARGYL++ ELTA KF D+PF Sbjct: 3611 ASVPIGKPISNIQLYMMAPGSMRLQPVGVPGELCIAGDGLARGYLNRPELTAEKFADHPF 3670 Query: 2017 MQGTKMYTTGDLARWLPNGELDVIGRLDNQVKIGGYRIELGEIESVAARHDKITQCVVAG 2076 G +MY TGDLARWLP+G ++ +GR+D+QVKI GYRIELGE+E+ + + + + VV Sbjct: 3671 EPGKRMYRTGDLARWLPDGNIEYLGRIDHQVKIRGYRIELGEVEAQLLKIEAVQEAVVTA 3730 Query: 2077 QPNSLGSQDLVLYFVAAEKISTSELVNFLSPVLPKYMMPQMYIQIDEIPLTANGKTNLKA 2136 + G + L YF A ++ SEL LS LP YM+P +IQ++ +PLTANGK + KA Sbjct: 3731 LEDGDGEKQLCAYFSANTELMVSELRIALSQELPGYMIPSYFIQLERLPLTANGKIDRKA 3790 Query: 2137 LPKP-GNVRPELRDDYEEAVTDLQKEIQQVWSLILNIEQVGIYDNFFEVGGNSLKIVAMY 2195 LP P G V+ + +Y T + ++ +W +L + ++G+ DNFF++GG+SL+ + Sbjct: 3791 LPAPEGGVQTGI--EYVAPRTAAEAQLAHIWQEVLGLPRIGVKDNFFDIGGHSLRATTLT 3848 Query: 2196 NELQKLYPGKIQITDIFSYPTISRLAQFIDNQSAFAEAAV----ALDHEGMAIELPAVYL 2251 +L K + + ++F PTI +AQ I A ++ A ++ ++ E +Y+ Sbjct: 3849 AKLHKEMGVSLPLREVFRSPTIEEMAQTITGMKHTAYTSIPTVEAKEYYAVSSEQKRLYI 3908 Query: 2252 -----AGEAEPDDGRVLRFSFAGDSYAGLVQACTRNRYEIIHLLLAGYVFLLSDICQRER 2306 G+ + V+R A D LV+ R + L G+ + + QR Sbjct: 3909 LNQLKCGKLSYNMPSVMRADGALDR--ELVEKAIRKLIQRHETLRTGFELIDGEPVQRIY 3966 Query: 2307 LAVQFS 2312 VQF+ Sbjct: 3967 DDVQFA 3972 Score = 1583 bits (4099), Expect = 0.0, Method: Compositional matrix adjust. Identities = 876/2256 (38%), Positives = 1307/2256 (57%), Gaps = 69/2256 (3%) Query: 11 FEKVIQKLNLKSDASRNPLFDVMFVLENLDYGLGPNEEQAKVKLIEPMAEVAKFDLTLTA 70 F K+++ L+++ + PL + L + + L E+ A L FDL Sbjct: 144 FRKMVRHLSVQYNDEHMPLIHTVVSLNEI-HSLQFKEDTATDTLFH-------FDL---- 191 Query: 71 KEAGGNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGGLDMLSNQEKHLLL 130 + L Y+ L+++ + ++ H +LL P + ++L +K LL Sbjct: 192 --ENNGIHLKLIYNGNLYDERYINQIVSHLDQLLFVILCQPQAAIHTAEILPEAQKQKLL 249 Query: 131 NVFKGTPTDYPKDKTIHELFEEQADRTPDQLAVVCGGQALTYSELNEQANSLASVLREKG 190 F T D+ +T+++LFEEQA+RTP+ AV LTY ELNE+A+ LA LR G Sbjct: 250 FDFNDTVRDFSGSRTVYQLFEEQAERTPENAAVKFKNDHLTYRELNEKASRLARTLRNCG 309 Query: 191 VGAEAIVGIMADRSLELIIAILGTLKAGGAYLPIDPEYPADRINYMLTDSQAAMLLFQHH 250 V + +V I+ADRSLE+I++I+ KAGGAY+P+DPEYP +R+ Y+L D+ A +LL QHH Sbjct: 310 VQPDTLVAILADRSLEMIVSIIAVWKAGGAYVPLDPEYPKERLQYLLHDADADVLLVQHH 369 Query: 251 IVKDLTYAGGRLELENSELYIRETG--NPVKASLPENLAYVIYTSGTTGTPKGVMVEHRN 308 + L + G ++L + Y + +PV +LAYVIYTSGTTG PKGVMVEH Sbjct: 370 LKNSLAFDGPVIDLNDEASYHADCSLLSPVAGH--SHLAYVIYTSGTTGKPKGVMVEHGG 427 Query: 309 LVNYIHWANKRYVAGEQTAFPLYSSISFDLTVTSIYTPLISGNTIVIYDGEDKALLTRTI 368 +VN + W + + FD + + + PLISG T+ + E+ T Sbjct: 428 IVNSLQWKKAFFKHSPADRVLVLYPYVFDAFILNFFGPLISGATLHLLPNEENK---ETF 484 Query: 369 AEENKVNIVKLT--PTHLRLLEDM--DLSRSS---IRTFIVGGEDLKIKVAEKIHRAFDG 421 A +N + ++T T RLL+ M ++R ++ +VGGE L+ EK+H + Sbjct: 485 AIQNAIKQERITHFSTSPRLLKTMIEQMNREDFIHVQHVVVGGEQLETDTVEKLH-SLQP 543 Query: 422 RIEIYNEYGPTEATVGCMIYKYNAERDKGTSVSIGIPADNTQLYIVGSRMELLPVGVAGE 481 RI I NEYGPTE +V + ++ + ++IG P N Q YI+G+ ++ P+G+ GE Sbjct: 544 RIRINNEYGPTENSV---VSTFHPVQSADEQITIGSPVANHQAYILGAHHQIQPIGIPGE 600 Query: 482 LCIGGDGVARGYLHKEALTAEKFVDHPFNAGSKLYKTGDMARWLSDGTVEYLGRMDNQVK 541 L +GG GVARGYL++ LT EKFV+H G K+YKTGD+ARWL DG +EYLGR+D+QVK Sbjct: 601 LYVGGAGVARGYLNRPELTEEKFVEHLHVPGQKMYKTGDLARWLPDGRIEYLGRIDHQVK 660 Query: 542 IRGYRIETGEIENRLLQMPDITEAVVVARTDEQGHNYLCAYVVSNKEVIASEVKGRLSKE 601 IRGYRIE GE+E + + ++ EA VVAR D G L AY V + A++ + LS+E Sbjct: 661 IRGYRIEIGEVEAAMFNLENVREAAVVAREDADGAKQLYAYYVGEPSLTAAQFREELSRE 720 Query: 602 LPNYMVPGFTVQIAKLPLSSNGKVDIKA----LPAVDISEMLAASYEAPNNKVEEILVDV 657 LPNYM+P + + ++PL+SNGK+D+KA LPA D + Y AP N +EE+L + Sbjct: 721 LPNYMIPSRFIPLERIPLTSNGKIDLKAYLKALPAADENTRAENEYIAPRNTIEELLASI 780 Query: 658 WQRVLNIEPIGTNYNYYEMGGDSIKSILIVSALREHGLRLEVKDLMQYPSIKELAGYVKH 717 WQ VL E IG N+++ GGDSIKSI + S L + G ++++K L ++PSI EL+ +V Sbjct: 781 WQEVLGAERIGILDNFFDFGGDSIKSIQVSSRLYQAGYKVDMKHLFKHPSIAELSQFVAP 840 Query: 718 EDVQAPQEAVEGSVPFLPVQQWFFEQGLPQENHYNQAFMFYRKEGLDEEILRKAVVAILV 777 A Q V G P+Q WFFEQ +P +HYNQA M Y EG E LR+ + I Sbjct: 841 VSRVADQGEVNGGTKLTPIQHWFFEQKMPHAHHYNQAVMLYSAEGFKEGPLRRTMERIAS 900 Query: 778 HHDALRMVYKRTPDGITQWNRSADCAGAAFTLDVYDLRGQ-DEKRSIPALSDELQKGLDL 836 HHDALRM++++TPDG D F L+V + +G+ D ++I ++E+Q + L Sbjct: 901 HHDALRMIFEKTPDGYAPRITGTD-ESELFHLEVMNYKGETDPAQAIADKANEIQSSMVL 959 Query: 837 EEGLLVKLGLFKTSLGDHLLVAVHHLVIDGVSWRILIADLETAYRNIAAGAAASLPPKTA 896 ++G LVKLGLF+ GDHLL+A+HHL+IDGVSWRIL+ D + Y LP KT Sbjct: 960 DKGPLVKLGLFQCPDGDHLLIAIHHLLIDGVSWRILLEDFASGYEQAERRQTIQLPQKTD 1019 Query: 897 SYRSWAQKLKEYASGKVLLKEAEYWKGITNTGSGPLPKDFGEENRGCGERMEVSLNFSKE 956 S+ WA +L +YA+ + +E YW +++ PLPKD E + EV++ ++KE Sbjct: 1020 SFPFWAGQLSKYAAETDMEEEIAYWTELSSIKPQPLPKDTISEGSLLRDSEEVTIQWTKE 1079 Query: 957 QTAKLLRNCNTAYNTQINDVLLCSLGLAFKEWGGMDQLLVSLEGHGREEIFQGVSIDRTI 1016 +T +LL+ N AYNT IND+LL SLGLA +W G + ++V+LEGHGRE I I RTI Sbjct: 1080 ETEQLLKQANRAYNTDINDLLLTSLGLAVHKWTGTEDIVVNLEGHGREPIIPDADISRTI 1139 Query: 1017 GWFTTIFPVVLDMTRSHDLAYSLKRTKEMLRHVPHKGIGYGIWKYLADGNKELRAFE--P 1074 GWFT+ +PVVL M +L+ +K KE LR +P KG+ Y I KY++ G+ E + + P Sbjct: 1140 GWFTSQYPVVLRMEAGKNLSQRIKIVKEGLRRIPDKGMNYSIIKYIS-GHSEADSLQLNP 1198 Query: 1075 EVSFNYLGEFGREAGSSLLEFSRLSSGASISIDNNKLKGIDINGLIMEGELELVFSYSTL 1134 E+SFNYLG+F ++ L S S+G S++ + + +D+NG+I EG L L SYS+ Sbjct: 1199 EISFNYLGQFDQDLKHQALRISPFSTGLSMNENQERTAVLDLNGMIAEGTLSLTLSYSSK 1258 Query: 1135 EYTRETVAQLTAAYHTSLLQVIDHCAHRQTAEKTPWDYGDPDLSLEDLDTLLACGQEI-- 1192 +Y R T+AQ SL +VI HC RQ TP D D+S+++L+ LL +E+ Sbjct: 1259 QYERSTMAQFARGLKESLQEVIAHCVSRQQTSLTPSDILLKDISIDELEQLLEQPRELGE 1318 Query: 1193 -EKIHSLSPMQEGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEILRT 1251 E I+ L+PMQ+GM+++++ D S YF+Q+ ++ G L ++ + L+ L+ KY+I RT Sbjct: 1319 AENIYPLTPMQKGMLFHSLFDPNSGAYFQQTMFDLHGDLEIDSFSKSLDGLSQKYDIFRT 1378 Query: 1252 AFFYHDIKKFKQAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDRSNPFDLEQDCLLR 1311 F+ + Q + K +K+ + D+ ++ + I+Q+ +D+ FDLE+ L+R Sbjct: 1379 NFYRGWKDQPLQIIFKTKKIGFQFNDLREMKESQKEAMIQQYAREDKMRGFDLEKGALMR 1438 Query: 1312 VAVLKTDTGNFKVVYSFHHIIMDGWSAGIILQEVIAQYKARLQEAELKQEKAVPYSDYLD 1371 + +L+TD ++ ++SFHHI+MDGW +I +E+ Y A LQ+ + +Q PYS Y++ Sbjct: 1439 LFILRTDEKTYRFIWSFHHILMDGWCLPLITKEIFENYFALLQQKQPEQSSITPYSQYIE 1498 Query: 1372 WLDHQDKAAALDYWQSYLEAYESGTVIPELQHQEKGFMHQQERTSLD--AQATAKLKSLA 1429 WL QD A YW YLE YE T +P+ H + ++ + D + ++K+K A Sbjct: 1499 WLGRQDAKEATAYWDQYLEGYEEQTGLPKDHHAAGDGRYVPDKVTCDICSDLSSKMKRTA 1558 Query: 1430 EANGITLSSVIQTAWGVVLQKYSN------THDVVFGSVVSGRPSDIKGIERMVGLCINT 1483 + +TL++++QT V+L KY+ + DVVFGSVVSGRP+ I +E M+GL INT Sbjct: 1559 GKHHVTLNTLLQTVCAVLLGKYNRAGTLCCSRDVVFGSVVSGRPAGIPNVETMIGLFINT 1618 Query: 1484 VPVRVTGGDQLSFIALAKKLNKDFIHANAFSFCQLAEIQALSPMKNNLINHVVVYENYPV 1543 +PVR +F L K+ + + + F L +IQA + K +LI H++++ENYPV Sbjct: 1619 IPVRFRCEAGTTFAELMKEAQERAVASQQFETHPLYDIQARTTQKQDLITHLMIFENYPV 1678 Query: 1544 DQSLADLQEAEGREVKITAAQGFEQTNYDLEILIAPGRTLQIKITYNGCKYSRDVINALM 1603 DQ + + G + I+ Q EQTNYD + + PG + I YN Y R I + Sbjct: 1679 DQYMESIGRQNGTSITISNVQMEEQTNYDFNLTVIPGDEMNISFEYNANVYDRASIERVR 1738 Query: 1604 DNLMHVLSCAVSNPDQAAESIDMVSEQERNKLLYELNCTGTAYAKEKTIAQLFEEQAERT 1663 ++ M +L V++ D + ++++E ER LL LN T + + + QLFEEQ+ERT Sbjct: 1739 EHFMQILHQVVTDADIRVDQAELLTEGERRTLLQTLNDTAAPFP-QTPVHQLFEEQSERT 1797 Query: 1664 PEAIALEFHGTVLSYRELNKRANQLARVLRRNSVGANVIVPILVKRSLNLLVGILGILKA 1723 P+ A+ L+Y ELNKRAN+LAR LR V + V I+ + S+ +VGIL +LK+ Sbjct: 1798 PDQAAVIDKDRQLTYGELNKRANRLARTLRAKGVQTDQPVAIITRNSIESVVGILAVLKS 1857 Query: 1724 GGGYLPLDTDYPVDRIHYMLQDSQASLLLTEKGLAAPLGLNEAVTILDIGSKQIQDEDDS 1783 GG Y+P+D +YP DRI YML DSQA ++L ++ + L +LD S Q D S Sbjct: 1858 GGAYVPIDPEYPQDRIRYMLDDSQAGIVLMQRDVRKQLAYEGVTVLLDDESSYHQ--DGS 1915 Query: 1784 NLQSITKADDLAYVLYTSGSTGNPKGVAVEQRGVHNFIKGITDRISFTEDKIILSVTTCS 1843 +L I LAYV+YTSGSTG PKGV +E G+ N+I E + S Sbjct: 1916 DLAPINDVSHLAYVIYTSGSTGRPKGVLIEHGGLTNYIWWAKKVYVKGEKANFPLYPSIS 1975 Query: 1844 FDIFGLESLLPLTRGLKVVIASEEEQKDPHLLNKVILDSEVNTIQLTPSRLKLMLNCSNT 1903 FD+ + PL G +++ E++ LL ++ D V+ I+LTP+ L++ L N Sbjct: 1976 FDLTVTSNFTPLVTGNAIIVYDGEDKTA--LLESIVRDPRVDIIKLTPAHLQV-LKEMNI 2032 Query: 1904 AESFKKLKLMMIGGEGFPKDLLVQLQKFTDSR--IYNMYGPTETTIWSTVKEL----THE 1957 A+ ++ M++GGE L + + D R I N YGPTET + + Sbjct: 2033 ADQ-TAVRRMIVGGENLSTRLARSIHEQFDGRIEICNEYGPTETVVGCMIYRYDAAKDRR 2091 Query: 1958 NSVNVGKPIANTQVYIVDQAGHLAPIGVAGELCIAGDGVARGYLHKEELTASKFVDNPFM 2017 SV +G ANT +Y++D+ APIGV GE+ I+G GVARGYL++ ELTA KFVD+PF Sbjct: 2092 ESVPIGTAAANTSIYVLDENMKPAPIGVPGEIYISGAGVARGYLNRPELTAEKFVDDPFE 2151 Query: 2018 QGTKMYTTGDLARWLPNGELDVIGRLDNQVKIGGYRIELGEIESVAARHDKITQCVVAGQ 2077 G KMY TGDLA+WL +G ++ GR+D QVKI GYRIELGEIE+ + + I + VV + Sbjct: 2152 PGAKMYKTGDLAKWLADGNIEYAGRIDEQVKIRGYRIELGEIEAALLQEEVIKEAVVTAR 2211 Query: 2078 PNSLGSQDLVLYFVAAEKISTSELVNFLSPVLPKYMMPQMYIQIDEIPLTANGKTNLKAL 2137 + G + L Y+V+ + + + L LS L YM+P +I++DE+PLT+NGK N K L Sbjct: 2212 EDVHGFKQLCAYYVSGGQTTAARLRKQLSQTLASYMVPAYFIELDEMPLTSNGKINKKGL 2271 Query: 2138 PKPGNVRPELRDDYEEAVTDLQKEIQQVWSLILNIEQVGIYDNFFEVGGNSLKIVAMYNE 2197 P P + + R +Y+ T ++ + W +L E V I DNFF++GG+S+K + + + Sbjct: 2272 PAP-DFELQDRAEYKAPRTKAEEILVSAWESVLGAENVSILDNFFDLGGDSIKSIQVSSR 2330 Query: 2198 L-QKLYPGKIQITDIFSYPTISRLAQFIDNQSAFAE 2232 L Q+ Y K++I D+F Y TI+ L+ I A+ Sbjct: 2331 LNQQGY--KMEIKDLFQYATIAELSPHIKQNLRIAD 2364 Score = 555 bits (1429), Expect = e-155, Method: Compositional matrix adjust. Identities = 344/1034 (33%), Positives = 556/1034 (53%), Gaps = 55/1034 (5%) Query: 1 LADFEHTHYQFEKVIQKLNLKSDASRNPLFDVMFVLENLDYGLGPNEEQAKVKLIEPMAE 60 L +E+ Y F++++ KLN+ D SR+PLFD MF+ +N + G ++ + A Sbjct: 4199 LKAYENQEYPFDELVDKLNVSRDFSRHPLFDTMFIWQNTEQGELSLDDVRFTPYPDNHA- 4257 Query: 61 VAKFDLTLTAKEAGGNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGGLDM 120 +AKFDLT A E + + Y++ L+ + T +RM +H+ +L+ A NP L L+M Sbjct: 4258 MAKFDLTFQAAENEDGITGMISYAAALYKQETAERMAKHFIQLIEAIANNPQAPLSSLEM 4317 Query: 121 LSNQEKHLLLNVFKGTPTDYPKDKTIHELFEEQADRTPDQLAVVCGGQALTYSELNEQAN 180 ++ +EK ++ + D P+DKTIH+LFEEQA+RTP+ A V TY ELNE+AN Sbjct: 4318 ITAKEKEQIVERWGQPAIDCPRDKTIHQLFEEQAERTPEHTAAVYEKSRFTYRELNERAN 4377 Query: 181 SLASVLREKGVGAEAIVGIMADRSLELIIAILGTLKAGGAYLPIDPEYPADRINYMLTDS 240 LA +LR +GV + VGI+A+RSLE+I+ I+ LKAGGAY+P+DP+ P +R+ Y+L DS Sbjct: 4378 RLARILRSEGVQPDQPVGILAERSLEMIVGIMAILKAGGAYVPMDPDSPQERLCYILEDS 4437 Query: 241 QAAMLLFQHHIVKDLTYAGGRLELENSELYIRETGNPVKASLPENLAYVIYTSGTTGTPK 300 A +LL Q H+ +++AG L L + + + N V A+ P++LAYVIYTSGTTG PK Sbjct: 4438 GAKVLLAQPHLQDRVSFAGEILLLNDERMNSGDGSNLVTAAGPDHLAYVIYTSGTTGKPK 4497 Query: 301 GVMVEHRNLVNYIHWANKRYVAGEQTAF--PLYSSISFDLTVTSIYTPLISGNTIVIY-- 356 G ++EHR +++ + + + L + FD +V I+ L+ G+ + I Sbjct: 4498 GTLIEHRQVLHLMEGLRGQVYGAYDSGLRVSLLAPYYFDASVKQIFAALLGGHALYIVPK 4557 Query: 357 ----DGEDKALLTRTIAEENKVNIVKLTPTHLRLLEDMD-LSRSSIRTFIVGGEDLKIKV 411 DG + RT +++++ TP+HL+LL D L +IR ++GGE L Sbjct: 4558 ASVSDGYALSNYYRT----HRIDVTDGTPSHLQLLIAADSLHGVTIRHMLIGGEALPQAT 4613 Query: 412 AEKIHRAFDGRIE----IYNEYGPTEATVGCMIYKYNAER----DKGTSVSIGIPADNTQ 463 ++ F I N YGPTE V ++ E D G V IG P N + Sbjct: 4614 VAQLLELFASNGSSMPLITNVYGPTETCVDASVFHIVPETLASADDGGYVPIGKPLGNNR 4673 Query: 464 LYIVGSRMELLPVGVAGELCIGGDGVARGYLHKEALTAEKFVDHPFNAGSKLYKTGDMAR 523 +YIV S +LP+GV GELCI GDGV RGYL+ LT EKFV PF G ++YKTGD+AR Sbjct: 4674 VYIVDSHDRMLPIGVKGELCIAGDGVGRGYLNLPELTGEKFVADPFVIGERMYKTGDLAR 4733 Query: 524 WLSDGTVEYLGRMDNQVKIRGYRIETGEIENRLLQMPDITEAVVVARTDEQGHNYLCAYV 583 +L DG +EY GR D+QVKIRGYRIE GE+E LL + + EAV++ R + +G + L AY Sbjct: 4734 YLPDGNIEYAGRKDHQVKIRGYRIELGEVEAALLNIEHVQEAVILVRENAEGQSDLYAYF 4793 Query: 584 VSNKEVIASEVKGRLSKELPNYMVPGFTVQIAKLPLSSNGKVDIKALPAVDISEMLAASY 643 K + +++K +LS ++P YMVP + +Q+ ++PL+SNGKV+ ALP + Y Sbjct: 4794 TGEKSLPINQLKEKLSDQIPGYMVPSYLMQLEQMPLTSNGKVNRSALPLPEAGLQTGIDY 4853 Query: 644 EAPNNKVEEILVDVWQRVLNIEPIGTNYNYYEMGGDSIKSILIVSAL-REHGLRLEVKDL 702 AP + EE LV +W+ VL +E +G N++++GG S++ + +V+ + ++ + ++++ Sbjct: 4854 VAPRTRPEEQLVHIWKEVLKVEQVGVKDNFFDLGGHSLRGMTLVTKIHKQFDKSISLREV 4913 Query: 703 MQYPSIKELAGYVKHEDVQAPQE----AVEGSVPFLPVQQWFF--EQGLPQENHYNQAFM 756 QYP+I+E+A + + P E + P VQ+ + Q E YN + Sbjct: 4914 FQYPTIEEMARVIAGAETSGPDEIPIAEAKDVYPVSSVQKMVYLSTQIEGGELSYNMPGI 4973 Query: 757 FYRKEGLDEEILRKAVVAILVHHDALRMVYKRTPDGITQWNRSADCAGAAFTLDVYDLRG 816 + +D L+ A +++ H++L+ ++ + Q + A F+++ Y + Sbjct: 4974 LTLEGRIDMNRLQSAFQSLIQRHESLQTGFEMIRGELVQVIKPQ----ADFSIERY--KA 5027 Query: 817 QDEKRSIPALSDELQKGLDLEEGLLVKLGLFKTSLGDHL-LVAVHHLVIDGVSWRILIAD 875 D + + L + +L + L++ GL + H+ + +HH+V DG S I + + Sbjct: 5028 ADGE--VEELFRNFVRPFNLSQAPLLRAGLIELEQDRHVFMFDMHHIVSDGASMNIFVEE 5085 Query: 876 LETAYRNIAAGAAASLPPKTASYRSWAQKLKEYASGKVLLKEAEYWKGITNTGSGP--LP 933 L Y L P Y+ + ++ + + ++ YW + + P LP Sbjct: 5086 LIQLYD------GKELTPLRIQYKDYTVWQQQAEQRERIKRQENYWLNVFHEELPPFELP 5139 Query: 934 KDFGEENRGC--GERMEVSLNFSKEQTAKLLRNC--NTAYNTQINDVLLCSLGLAFKEWG 989 KDF G+R +L+ + Q K + +TAY +LL + + ++ Sbjct: 5140 KDFARPRIRSFEGKRYNFALDETVVQGIKQMEELTGSTAYM-----ILLSAYNILLAKYS 5194 Query: 990 GMDQLLVSLEGHGR 1003 G + ++V GR Sbjct: 5195 GQEDIVVGTPIAGR 5208 Score = 550 bits (1416), Expect = e-153, Method: Compositional matrix adjust. Identities = 334/967 (34%), Positives = 526/967 (54%), Gaps = 66/967 (6%) Query: 74 GGNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGGLDMLSNQEKHLLLNVF 133 G L ++ + ++ +R+ H+ +L+ + P ++ +++L+ QEK L + F Sbjct: 3222 GEQLTVHFSFNRNEYEQSEAERIRGHFEQLMQQVLQLPSVKVEEMELLTQQEKEQLHSRF 3281 Query: 134 KGTPTDYPKDKTIHELFEEQADRTPDQLAVVCGGQALTYSELNEQANSLASVLREKGVGA 193 + YP+++TIH+LFEEQA RTPD AV+ Q +TY ELNE+AN LA LR +G+ A Sbjct: 3282 QSNEMHYPREQTIHQLFEEQALRTPDHEAVIFEEQRMTYLELNERANQLARTLRAEGLQA 3341 Query: 194 EAIVGIMADRSLELIIAILGTLKAGGAYLPIDPEYPADRINYMLTDSQAAMLLFQHHIVK 253 + +V IMA+RSLE+++ I LKAGGAY+PIDP+YP +RI Y+L DS A +LL Q H+ + Sbjct: 3342 DQLVAIMAERSLEMMVGIYAILKAGGAYVPIDPDYPEERIRYILEDSGATLLLSQRHVKE 3401 Query: 254 DLTYAGGRLELENSELYIRETGNPVKASLPENLAYVIYTSGTTGTPKGVMVEHRNLVNYI 313 + +AG ++L+++ +Y + N S + AYVIYTSG+TG PKGVMVEHR ++N + Sbjct: 3402 RVAFAGTVIDLDDTSVYDDDVSNLDPLSGAGDRAYVIYTSGSTGKPKGVMVEHRPVINRL 3461 Query: 314 HWANKRYVAGEQTAFPLYSSISFDLTVTSIYTPLISGNTIVIYD--GEDKALLTRTIAEE 371 W K Y G ++I+FD++V ++ ++G + + GE + EE Sbjct: 3462 MWMQKAYPIGSGDTILQKTAITFDVSVWELFWWALTGAKVCLLPLGGEKDPEVIWNTIEE 3521 Query: 372 NKVNIVKLTPTHLRLLEDMDLSRS---------SIRTFIVGGEDLKIKVAEKIHRAFD-- 420 + + P L +++ ++R GE L + HR Sbjct: 3522 QSITTMHFVPAMLHAFLKFAETQTASGQTSKLRTLRQVFASGEALMPAHTARFHRLITPV 3581 Query: 421 GRIEIYNEYGPTEATVGCMIYKYNAERDKG-TSVSIGIPADNTQLYIVG-SRMELLPVGV 478 ++ N YGPTEATV + +N E ++ SV IG P N QLY++ M L PVGV Sbjct: 3582 NGAQLINLYGPTEATVD--VSYFNCEANQAYASVPIGKPISNIQLYMMAPGSMRLQPVGV 3639 Query: 479 AGELCIGGDGVARGYLHKEALTAEKFVDHPFNAGSKLYKTGDMARWLSDGTVEYLGRMDN 538 GELCI GDG+ARGYL++ LTAEKF DHPF G ++Y+TGD+ARWL DG +EYLGR+D+ Sbjct: 3640 PGELCIAGDGLARGYLNRPELTAEKFADHPFEPGKRMYRTGDLARWLPDGNIEYLGRIDH 3699 Query: 539 QVKIRGYRIETGEIENRLLQMPDITEAVVVARTDEQGHNYLCAYVVSNKEVIASEVKGRL 598 QVKIRGYRIE GE+E +LL++ + EAVV A D G LCAY +N E++ SE++ L Sbjct: 3700 QVKIRGYRIELGEVEAQLLKIEAVQEAVVTALEDGDGEKQLCAYFSANTELMVSELRIAL 3759 Query: 599 SKELPNYMVPGFTVQIAKLPLSSNGKVDIKALPAVDISEMLAASYEAPNNKVEEILVDVW 658 S+ELP YM+P + +Q+ +LPL++NGK+D KALPA + Y AP E L +W Sbjct: 3760 SQELPGYMIPSYFIQLERLPLTANGKIDRKALPAPEGGVQTGIEYVAPRTAAEAQLAHIW 3819 Query: 659 QRVLNIEPIGTNYNYYEMGGDSIKSILIVSAL-REHGLRLEVKDLMQYPSIKELAGYVKH 717 Q VL + IG N++++GG S+++ + + L +E G+ L ++++ + P+I+E+A Sbjct: 3820 QEVLGLPRIGVKDNFFDIGGHSLRATTLTAKLHKEMGVSLPLREVFRSPTIEEMA----- 3874 Query: 718 EDVQAPQEAVEGSVPFLPVQQWF-----------FEQGLPQENHYNQAFMFYRKEGLDEE 766 + + + S+P + ++++ Q + YN + LD E Sbjct: 3875 QTITGMKHTAYTSIPTVEAKEYYAVSSEQKRLYILNQLKCGKLSYNMPSVMRADGALDRE 3934 Query: 767 ILRKAVVAILVHHDALRMVYKRTPDGITQWNRSADCAGAA-FTLDVYDLRGQDEKRSIPA 825 ++ KA+ ++ H+ LR ++ DG D A FT Q ++ A Sbjct: 3935 LVEKAIRKLIQRHETLRTGFELI-DGEPVQRIYDDVQFAVEFT--------QAKEEQAEA 3985 Query: 826 LSDELQKGLDLEEGLLVKLGLFKTSLGDHLLV-AVHHLVIDGVSWRILIADLETAYRNIA 884 L + DLE+ L+++GL + + HLL+ +HH++ DGVS + LI + + Y Sbjct: 3986 LVHGFVRAFDLEKAPLLRVGLIELAKDRHLLLFDMHHIISDGVSIKNLIEEFVSLYE--- 4042 Query: 885 AGAAASLPPKTASYRSWAQ-KLKEYASGKVLLKEAEYWKGITNTGSGP---LPKDFGEEN 940 LPP Y+ +A +L + S ++ +EA YW + +G P +P D+G Sbjct: 4043 ---GKELPPLRVQYKDYAAWQLSDMQSERMKKQEA-YWLDVF-SGEVPVLDMPTDYGRPA 4097 Query: 941 RGCGERMEVSLNFSKEQTAKL----LRNCNTAYNTQINDVLLCSLGLAFKEWGGMDQLLV 996 E ++ E T +L L++ +T Y VLL + ++ G + ++V Sbjct: 4098 ARSFEGGQIEFVIGPELTEQLKGLALKSESTLYM-----VLLAAYTTMLAKYSGQEDIVV 4152 Query: 997 SLEGHGR 1003 GR Sbjct: 4153 GSPIAGR 4159 Score = 496 bits (1277), Expect = e-137, Method: Compositional matrix adjust. Identities = 332/1067 (31%), Positives = 558/1067 (52%), Gaps = 65/1067 (6%) Query: 1191 EIEKIHSLSPMQEGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEILR 1250 E ++ +++S Q+ + + G +Y S + +G L+ E++ + +L ++E LR Sbjct: 3892 EAKEYYAVSSEQKRLYILNQLKCGKLSYNMPSVMRADGALDRELVEKAIRKLIQRHETLR 3951 Query: 1251 TAFFYHDIKKFKQAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDRSNPFDLEQDCLL 1310 T F D + Q + + + + + +++ +EQ+ + V FDLE+ LL Sbjct: 3952 TGFELIDGEPV-QRIYDDVQFAVEF----TQAKEEQAEAL----VHGFVRAFDLEKAPLL 4002 Query: 1311 RVAVLKTDTGNFKVVYSFHHIIMDGWSAGIILQEVIAQYKARLQEAELKQEKAVPYSDYL 1370 RV +++ +++ HHII DG S +++E ++ Y+ + EL + V Y DY Sbjct: 4003 RVGLIELAKDRHLLLFDMHHIISDGVSIKNLIEEFVSLYEGK----ELPPLR-VQYKDYA 4057 Query: 1371 DWLDHQDKAAALDYWQSYLEAYESGTVIPEL-------QHQEKGFMHQQERTSLDAQATA 1423 W ++ + ++Y SG V P L + + F Q + + T Sbjct: 4058 AWQLSDMQSERMKKQEAYWLDVFSGEV-PVLDMPTDYGRPAARSFEGGQIEFVIGPELTE 4116 Query: 1424 KLKSLAEANGITLSSVIQTAWGVVLQKYSNTHDVVFGSVVSGRPSDIKGIERMVGLCINT 1483 +LK LA + TL V+ A+ +L KYS D+V GS ++GR +E ++G+ + T Sbjct: 4117 QLKGLALKSESTLYMVLLAAYTTMLAKYSGQEDIVVGSPIAGRTH--SDLESLIGMFVGT 4174 Query: 1484 VPVRVTGGDQLSFIALAKKLNKDFIHA---NAFSFCQLAEIQALSP--MKNNLINHVVVY 1538 + +R + +F +++ + + A + F +L + +S ++ L + + ++ Sbjct: 4175 LAIRTNPVGEKTFREYVQEVKEHTLKAYENQEYPFDELVDKLNVSRDFSRHPLFDTMFIW 4234 Query: 1539 ENYPVDQSLADLQEAEGREVKITA-AQGFEQTNYDLEILIAPGRT-LQIKITYNGCKYSR 1596 +N + E +V+ T +DL A + I+Y Y + Sbjct: 4235 QN-------TEQGELSLDDVRFTPYPDNHAMAKFDLTFQAAENEDGITGMISYAAALYKQ 4287 Query: 1597 DVINALMDNLMHVLSCAVSNPDQAAESIDMVSEQERNKLLYELNCTGTAYAKEKTIAQLF 1656 + + + + ++ +NP S++M++ +E+ +++ ++KTI QLF Sbjct: 4288 ETAERMAKHFIQLIEAIANNPQAPLSSLEMITAKEKEQIVERWGQPAIDCPRDKTIHQLF 4347 Query: 1657 EEQAERTPEAIALEFHGTVLSYRELNKRANQLARVLRRNSVGANVIVPILVKRSLNLLVG 1716 EEQAERTPE A + + +YRELN+RAN+LAR+LR V + V IL +RSL ++VG Sbjct: 4348 EEQAERTPEHTAAVYEKSRFTYRELNERANRLARILRSEGVQPDQPVGILAERSLEMIVG 4407 Query: 1717 ILGILKAGGGYLPLDTDYPVDRIHYMLQDSQASLLLTEKGLAAPLGLNEAVTILDIGSKQ 1776 I+ ILKAGG Y+P+D D P +R+ Y+L+DS A +LL + L + A IL + ++ Sbjct: 4408 IMAILKAGGAYVPMDPDSPQERLCYILEDSGAKVLLAQPHLQDRVSF--AGEILLLNDER 4465 Query: 1777 IQDEDDSNLQSITKADDLAYVLYTSGSTGNPKGVAVEQRGVHNFIKGITDRISFTEDKII 1836 + D SNL + D LAYV+YTSG+TG PKG +E R V + ++G+ ++ D Sbjct: 4466 MNSGDGSNLVTAAGPDHLAYVIYTSGTTGKPKGTLIEHRQVLHLMEGLRGQVYGAYDSG- 4524 Query: 1837 LSVTTCS---FDIFGLESLLPLTRGLKVVIASEEEQKDPHLLNKVILDSEVNTIQLTPSR 1893 L V+ + FD + L G + I + D + L+ ++ TPS Sbjct: 4525 LRVSLLAPYYFDASVKQIFAALLGGHALYIVPKASVSDGYALSNYYRTHRIDVTDGTPSH 4584 Query: 1894 LKLMLNCSNTAESFK--KLKLMMIGGEGFPKDLLVQLQKFTDSR------IYNMYGPTET 1945 L+L++ A+S ++ M+IGGE P+ + QL + S I N+YGPTET Sbjct: 4585 LQLLI----AADSLHGVTIRHMLIGGEALPQATVAQLLELFASNGSSMPLITNVYGPTET 4640 Query: 1946 TIWSTVKELTHEN--------SVNVGKPIANTQVYIVDQAGHLAPIGVAGELCIAGDGVA 1997 + ++V + E V +GKP+ N +VYIVD + PIGV GELCIAGDGV Sbjct: 4641 CVDASVFHIVPETLASADDGGYVPIGKPLGNNRVYIVDSHDRMLPIGVKGELCIAGDGVG 4700 Query: 1998 RGYLHKEELTASKFVDNPFMQGTKMYTTGDLARWLPNGELDVIGRLDNQVKIGGYRIELG 2057 RGYL+ ELT KFV +PF+ G +MY TGDLAR+LP+G ++ GR D+QVKI GYRIELG Sbjct: 4701 RGYLNLPELTGEKFVADPFVIGERMYKTGDLARYLPDGNIEYAGRKDHQVKIRGYRIELG 4760 Query: 2058 EIESVAARHDKITQCVVAGQPNSLGSQDLVLYFVAAEKISTSELVNFLSPVLPKYMMPQM 2117 E+E+ + + + V+ + N+ G DL YF + + ++L LS +P YM+P Sbjct: 4761 EVEAALLNIEHVQEAVILVRENAEGQSDLYAYFTGEKSLPINQLKEKLSDQIPGYMVPSY 4820 Query: 2118 YIQIDEIPLTANGKTNLKALPKPGNVRPELRDDYEEAVTDLQKEIQQVWSLILNIEQVGI 2177 +Q++++PLT+NGK N ALP P + DY T ++++ +W +L +EQVG+ Sbjct: 4821 LMQLEQMPLTSNGKVNRSALPLP-EAGLQTGIDYVAPRTRPEEQLVHIWKEVLKVEQVGV 4879 Query: 2178 YDNFFEVGGNSLKIVAMYNELQKLYPGKIQITDIFSYPTISRLAQFI 2224 DNFF++GG+SL+ + + ++ K + I + ++F YPTI +A+ I Sbjct: 4880 KDNFFDLGGHSLRGMTLVTKIHKQFDKSISLREVFQYPTIEEMARVI 4926 Score = 95.5 bits (236), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 94/452 (20%), Positives = 197/452 (43%), Gaps = 42/452 (9%) Query: 1191 EIEKIHSLSPMQEGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEILR 1250 E + ++ +S +Q+ + +T ++ G +Y L +EG +++ L L ++E L+ Sbjct: 4941 EAKDVYPVSSVQKMVYLSTQIEGGELSYNMPGILTLEGRIDMNRLQSAFQSLIQRHESLQ 5000 Query: 1251 TAFFYHDIKKFKQAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDRSNPFDLEQDCLL 1310 T F I+ V+K + D S + +E+ ++ PF+L Q LL Sbjct: 5001 TGF--EMIRGELVQVIKPQA------DFSIERYKAADGEVEEL-FRNFVRPFNLSQAPLL 5051 Query: 1311 RVAVLKTDTGNFKVVYSFHHIIMDGWSAGIILQEVIAQYKARLQEAELKQEKAVPYSDYL 1370 R +++ + ++ HHI+ DG S I ++E+I Y + EL + + Y DY Sbjct: 5052 RAGLIELEQDRHVFMFDMHHIVSDGASMNIFVEELIQLYDGK----ELTPLR-IQYKDYT 5106 Query: 1371 DWLDHQDKAAAL----DYWQSYLEAYESGTVIPE--LQHQEKGFMHQQERTSLDAQATAK 1424 W ++ + +YW + +P+ + + + F ++ +LD Sbjct: 5107 VWQQQAEQRERIKRQENYWLNVFHEELPPFELPKDFARPRIRSFEGKRYNFALDETVVQG 5166 Query: 1425 LKSLAEANGITLSSVIQTAWGVVLQKYSNTHDVVFGSVVSGRPSDIKGIERMVGLCINTV 1484 +K + E G T ++ +A+ ++L KYS D+V G+ ++GR + ++ ++G+ +NT+ Sbjct: 5167 IKQMEELTGSTAYMILLSAYNILLAKYSGQEDIVVGTPIAGRMHE--DLQHIIGMFVNTL 5224 Query: 1485 PVRVTGGDQLSFIALAKKLNKDFIHA---NAFSFCQLAEIQALSP--MKNNLINHVVVYE 1539 +R + +F+ + + + A + F +L E + +N L + + V + Sbjct: 5225 AIRTAPAGEKTFMDYVTETKETMLKAYENQEYPFEELVEKLGVKRDLSRNPLFDTMFVLQ 5284 Query: 1540 NYPVDQSLADLQEAEGREVKITAAQGFEQTN----YDLEI-LIAPGRTLQIKITYNGCKY 1594 N E E+ A + +EQTN +DL++ + +Q Y + Sbjct: 5285 N----------TEQTDIELDSLAVRPYEQTNTAAKFDLQLTFVMNPHEIQGSFEYCTKLF 5334 Query: 1595 SRDVINALMDNLMHVLSCAVSNPDQAAESIDM 1626 + I L + +LS + +P + I + Sbjct: 5335 KQKTIATLSKDYAMILSAIIKDPSIPLKEIQL 5366 Score = 72.0 bits (175), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 42/118 (35%), Positives = 64/118 (54%), Gaps = 15/118 (12%) Query: 1 LADFEHTHYQFEKVIQKLNLKSDASRNPLFDVMFVLENLDYGLGPNEEQAKVKL----IE 56 L +E+ Y FE++++KL +K D SRNPLFD MFVL+N EQ ++L + Sbjct: 5248 LKAYENQEYPFEELVEKLGVKRDLSRNPLFDTMFVLQNT--------EQTDIELDSLAVR 5299 Query: 57 PMAEV---AKFDLTLTAKEAGGNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANP 111 P + AKFDL LT + S EY ++LF + T+ + + YA +L+ +P Sbjct: 5300 PYEQTNTAAKFDLQLTFVMNPHEIQGSFEYCTKLFKQKTIATLSKDYAMILSAIIKDP 5357 >B3TLA2.1 B3TLA2_BACSU Iturin A synthetase B Length = 5362 Score = 1757 bits (4551), Expect = 0.0, Method: Compositional matrix adjust. Identities = 909/2200 (41%), Positives = 1361/2200 (61%), Gaps = 33/2200 (1%) Query: 58 MAEVAKFDLTLTAKEAGGNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGG 117 M E +D LT G ++ S EY++ ++ +A+++R+ EH+ ++L + + D + Sbjct: 1690 MEEQTNYDFNLTVI-PGDEMNISFEYNANVYERASIERVREHFMQILHQVVTDADIRVDQ 1748 Query: 118 LDMLSNQEKHLLLNVFKGTPTDYPKDKTIHELFEEQADRTPDQLAVVCGGQALTYSELNE 177 ++L+ E+ LL T +P+ +H+LFEEQ+ RTPDQ AV+ + LTY ELN+ Sbjct: 1749 AELLTEGERRTLLQTLNDTAAPFPQ-TPVHQLFEEQSQRTPDQAAVIDKDRQLTYGELNK 1807 Query: 178 QANSLASVLREKGVGAEAIVGIMADRSLELIIAILGTLKAGGAYLPIDPEYPADRINYML 237 +AN LA LR KGV + V I+ S+E ++ IL LK+GGAY+PIDPEYP DRI YML Sbjct: 1808 RANRLARTLRAKGVQTDQPVAIITRNSIESVVGILAVLKSGGAYVPIDPEYPQDRIRYML 1867 Query: 238 TDSQAAMLLFQHHIVKDLTYAGGRLELENSELYIRETGNPVKASLPENLAYVIYTSGTTG 297 DSQA ++L Q + K L Y G + L++ Y ++ + S +LAYVIYTSG+TG Sbjct: 1868 DDSQAGIVLMQRDVRKQLAYEGVTVLLDDESSYHQDGSDLAPISDVSHLAYVIYTSGSTG 1927 Query: 298 TPKGVMVEHRNLVNYIHWANKRYVAGEQTAFPLYSSISFDLTVTSIYTPLISGNTIVIYD 357 PKGV++EH L NYI WA + YV GE+ FPLYSSISFDLTVTSI+TPL++GN I++YD Sbjct: 1928 RPKGVLIEHGGLTNYIWWAKEVYVKGEKANFPLYSSISFDLTVTSIFTPLVTGNAIIVYD 1987 Query: 358 GEDKALLTRTIAEENKVNIVKLTPTHLRLLEDMDLS-RSSIRTFIVGGEDLKIKVAEKIH 416 GEDK L +I + +V+I+KLTP HL++L++M+++ ++++R IVGGE+L ++A IH Sbjct: 1988 GEDKTALLESIVRDPRVDIIKLTPAHLQVLKEMNIADQTAVRRMIVGGENLSTRLARSIH 2047 Query: 417 RAFDGRIEIYNEYGPTEATVGCMIYKYNAERDKGTSVSIGIPADNTQLYIVGSRMELLPV 476 F+GRIEI NEYGPTE VGCMIY+Y+A +D+ SV IG A NT +Y++ M+ P+ Sbjct: 2048 EQFEGRIEICNEYGPTETVVGCMIYRYDAAKDRRESVPIGTAAANTSIYVLDENMKPAPI 2107 Query: 477 GVAGELCIGGDGVARGYLHKEALTAEKFVDHPFNAGSKLYKTGDMARWLSDGTVEYLGRM 536 GV GE+ I G GVARGYL++ LTAEKFVD PF G+K+YKTGD+A+WL+DG +EY GR+ Sbjct: 2108 GVPGEIYISGAGVARGYLNRPELTAEKFVDDPFEPGAKMYKTGDLAKWLADGNIEYAGRI 2167 Query: 537 DNQVKIRGYRIETGEIENRLLQMPDITEAVVVARTDEQGHNYLCAYVVSNKEVIASEVKG 596 D QVKIRGYRIE GEIE LLQ I EAVV AR D G LCAY VS + A+ ++ Sbjct: 2168 DEQVKIRGYRIELGEIEAALLQEEVIKEAVVTAREDVHGFKQLCAYYVSGGQTTAARLRK 2227 Query: 597 RLSKELPNYMVPGFTVQIAKLPLSSNGKVDIKALPAVDISEMLAASYEAPNNKVEEILVD 656 +LS+ L +YMVP + +++ ++PL+SNGK++ K LPA D A Y+AP K EEILV Sbjct: 2228 QLSQTLASYMVPAYFIELDEMPLTSNGKINKKGLPAPDFELQDRAEYKAPRTKAEEILVS 2287 Query: 657 VWQRVLNIEPIGTNYNYYEMGGDSIKSILIVSALREHGLRLEVKDLMQYPSIKELAGYVK 716 W+ VL E + N++++GGDSIKSI + S L + G ++E+KDL QY +I EL+ ++K Sbjct: 2288 AWESVLGAENVSILDNFFDLGGDSIKSIQVSSRLNQQGYKMEIKDLFQYATIAELSPHIK 2347 Query: 717 HEDVQAPQEAVEGSVPFLPVQQWFFEQGLPQENHYNQAFMFYRKEGLDEEILRKAVVAIL 776 A Q V+G V P+Q WFFEQ +++YNQA M + EG E LR+ + + Sbjct: 2348 QNLRIADQGEVKGKVSLTPIQHWFFEQTTTDQHYYNQAVMLHAPEGFQETQLRQTLQKLA 2407 Query: 777 VHHDALRMVYKRTPDGITQWNRSADCAGAAFTLDVYDLR-GQDEKRSIPALSDELQKGLD 835 HHDALRM ++ T +G N +G + L+V +L+ D R+I A +DE+Q + Sbjct: 2408 EHHDALRMTFRTTENGCEAQNEEIAQSG-LYRLEVMNLKEDPDPGRTIEAKADEIQSSMH 2466 Query: 836 LEEGLLVKLGLFKTSLGDHLLVAVHHLVIDGVSWRILIADLETAYRNIAAGAAASLPPKT 895 L +G L+K GLF+ + GDHLL+A+HHL+IDG+SWRIL+ D+ + Y+ G LP KT Sbjct: 2467 LSDGPLMKAGLFQCADGDHLLIAIHHLIIDGISWRILLEDIVSGYKQAENGRVIQLPQKT 2526 Query: 896 ASYRSWAQKLKEYASGKVLLKEAEYWKGITNTGSGPLPKDFGEENRGCGERMEVSLNFSK 955 S++ WA++L EYA + + +E EYW I T PLPKDF E + + ++ ++K Sbjct: 2527 DSFQLWAKRLSEYAQSETIKQEQEYWTKIEQTEVKPLPKDFHETHTTAKDSETAAVEWTK 2586 Query: 956 EQTAKLLRNCNTAYNTQINDVLLCSLGLAFKEWGGMDQLLVSLEGHGREEIFQGVSIDRT 1015 E+T LL+ N AY+T+IND+LL SLGL+ W G++Q+ + LEGHGRE+I Q + I RT Sbjct: 2587 EETELLLKQANRAYHTEINDLLLTSLGLSISHWSGLEQIPIHLEGHGREQIIQDIDISRT 2646 Query: 1016 IGWFTTIFPVVLDMTRSHDLAYSLKRTKEMLRHVPHKGIGYGIWKYLADGNKELRAFEPE 1075 +GWFT+++PVVL +++ +K TKE LR +PHKGIGYGI +YL+ G PE Sbjct: 2647 VGWFTSLYPVVLHAQPGKEISDYIKTTKEGLRQIPHKGIGYGIARYLSGGMPS--KLNPE 2704 Query: 1076 VSFNYLGEFGREAGSSLLEFSRLSSGASISIDNNKLKGIDINGLIMEGELELVFSYSTLE 1135 +SFNYLG+F ++ ++ S S G+ S + ++ING+I +G L+L SYS+ + Sbjct: 2705 ISFNYLGQFDQDLQRHGVQLSSYSCGSDSSGHQERPYVLNINGMITDGRLKLTISYSSKQ 2764 Query: 1136 YTRETVAQLTAAYHTSLLQVIDHCAHRQTAEKTPWDYGDPDLSLEDLDTL---LACGQEI 1192 Y +ET+ +L+ + L +I HC H++ +E TP D +S+++LD L L E+ Sbjct: 2765 YAKETIMRLSETIQSRLRTIITHCVHKEQSELTPSDILLKGISIDELDQLLIQLPHAGEV 2824 Query: 1193 EKIHSLSPMQEGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEILRTA 1252 E ++ L+PMQ+GM++++++D SS+YFEQ+ +++G L ++ L L Y +LRT Sbjct: 2825 ENVYPLTPMQKGMLFHSLLDEASSSYFEQASFDLQGELKIDWFKASLERLFETYAVLRTR 2884 Query: 1253 FFYHDIKKFKQAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDRSNPFDLEQDCLLRV 1312 F+ Q V K + +IH+ D+ + I ++ +D++ FDL +D L+R+ Sbjct: 2885 FYSGWNDTPLQIVYKTQTPQIHFADLRDIEEHLREDAIAAYQREDKAKGFDLARDPLMRI 2944 Query: 1313 AVLKTDTGNFKVVYSFHHIIMDGWSAGIILQEVIAQYKARLQEAELKQEKAVPYSDYLDW 1372 A+ + + + +++SFHHI+MDGW +I +EV Y A + E + AVPYSDY++W Sbjct: 2945 AIFRMEDRKYHLIWSFHHIVMDGWCLSLITKEVFDHYSALQEGREPEPLSAVPYSDYIEW 3004 Query: 1373 LDHQDKAAALDYWQSYLEAYESGTVIPE--LQHQEKGFMHQQERTSLDAQATAKLKSLAE 1430 LD QD+ AA YW YLE Y+ T + QH++K + + D + T +L+ +A Sbjct: 3005 LDRQDQGAAKRYWSGYLEGYKGETTLLHKIAQHEQKEYAYANLICRFDHEQTKQLQQIAN 3064 Query: 1431 ANGITLSSVIQTAWGVVLQKYSNTHDVVFGSVVSGRPSDIKGIERMVGLCINTVPVRVTG 1490 + +TL+++IQT WGV+LQKYS + DVVFGSVVSGRP++I +E+M+GL INT+PVR+ Sbjct: 3065 QHQVTLNTLIQTLWGVLLQKYSGSADVVFGSVVSGRPAEIPDVEQMIGLFINTIPVRIRC 3124 Query: 1491 GDQLSFIALAKKLNKDFIHANAFSFCQLAEIQALSPMKNNLINHVVVYENYPVDQSLADL 1550 + +F + + ++ + + ++ L EIQA + K NLI+H++++ENYP+ Q A+ Sbjct: 3125 DEDSTFADTMQMVQQNALASQSYDTYPLYEIQAQTEQKQNLIDHIMIFENYPIGQQ-AEE 3183 Query: 1551 QEAEGREVKITAAQGFEQTNYDLEILIAPGRTLQIKITYNGCKYSRDVINALMDNLMHVL 1610 G E+ IT E ++YDL +++ PG+ L + +N +Y + + L + ++ Sbjct: 3184 TGHHGTELNITNFHMQEHSHYDLNVVVIPGKQLAVHFGFNENEYEKSEVERLRGHFEKLM 3243 Query: 1611 SCAVSNPDQAAESIDMVSEQERNKLLYELNCTGTAYAKEKTIAQLFEEQAERTPEAIALE 1670 + P E ++++++QE+ LL Y +EKTI +LFEEQA RTP+ A+ Sbjct: 3244 QQVLRQPSVKIEDLELLTQQEKEYLLSRFQSNDMHYPREKTIHELFEEQAHRTPDNTAVV 3303 Query: 1671 FHGTVLSYRELNKRANQLARVLRRNSVGANVIVPILVKRSLNLLVGILGILKAGGGYLPL 1730 F G +Y ELN+RANQLAR L+ V A+ +V I+ +RSL ++VGILG+LKAGG YLP+ Sbjct: 3304 FEGKQFTYEELNRRANQLARTLQAKGVQADQLVGIMTERSLEMVVGILGVLKAGGAYLPI 3363 Query: 1731 DTDYPVDRIHYMLQDSQASLLLTEKGLAAPLGLNEAVTILDIGSKQIQDEDDSNLQSITK 1790 D D P +RI Y+L DS S+LL L +G + T +D+ + E DS+L + Sbjct: 3364 DPDSPSERIRYILNDSSISVLLYCGKLQDDIGF--SGTCIDLMEEHFYHEKDSSLALSYQ 3421 Query: 1791 ADDLAYVLYTSGSTGNPKGVAVEQRGVHNFIKGITDRI--SFTEDKIILSVTTCSFDIFG 1848 + LAY +YTSG+TG PKG +E R V + I+G++ ++ ++ + I + FD Sbjct: 3422 SSQLAYAIYTSGTTGKPKGTLIEHRQVIHLIEGLSRQVYSAYDAELNIAMLAPYYFDASV 3481 Query: 1849 LESLLPLTRGLKVVIASEEEQKDPHLLNKVILDSEVNTIQLTPSRLKLMLNCSNTAESFK 1908 + L G + I +E D L + ++ TP+ LKL++ + Sbjct: 3482 QQMYASLLSGHTLFIVPKEIVSDGAALCRYYRQHSIDITDGTPAHLKLLIAAGDLQGV-- 3539 Query: 1909 KLKLMMIGGEGFPKDLLVQLQKFTDSR-----IYNMYGPTETTIWSTVKEL--------T 1955 L+ ++IGGE K + +L++ I N+YGPTET + +++ + Sbjct: 3540 TLQHLLIGGEALSKTTVNKLKQLFGEHGAAPGITNVYGPTETCVDASLFNIECSSDAWAR 3599 Query: 1956 HENSVNVGKPIANTQVYIVDQAGHLAPIGVAGELCIAGDGVARGYLHKEELTASKFVDNP 2015 +N V +GKP+ ++YI+D L P GV GEL IAGDGV RGYL+ ELT KFV +P Sbjct: 3600 SQNYVPIGKPLGRNRMYILDSKKRLQPKGVQGELYIAGDGVGRGYLNLPELTDEKFVADP 3659 Query: 2016 FMQGTKMYTTGDLARWLPNGELDVIGRLDNQVKIGGYRIELGEIESVAARHDKITQCVVA 2075 F+ +MY TGDLAR LP+G ++ IGR+D+QVKI G+RIELGEIESV I + A Sbjct: 3660 FVPEDRMYRTGDLARLLPDGNIEYIGRIDHQVKIQGFRIELGEIESVMLNVPDIQEAAAA 3719 Query: 2076 GQPNSLGSQDLVLYFVAAEKISTSELVNFLSPVLPKYMMPQMYIQIDEIPLTANGKTNLK 2135 ++ L YF A + I SEL ++ LP YM+P ++Q+D++PLT NGK N + Sbjct: 3720 ALKDADDEYYLCGYFAADKTIQISELRKRMARHLPGYMIPAHFVQLDKMPLTPNGKLNRQ 3779 Query: 2136 ALPKPGNVRPELRDDYEEAVTDLQKEIQQVWSLILNIEQVGIYDNFFEVGGNSLKIVAMY 2195 LP P R + +Y T + ++ +W +L +EQVGI D+FFE+GG+SL+ A+ Sbjct: 3780 LLPAPVKKR-DSGIEYVPPQTSAEIQLTAIWEDVLGLEQVGIRDHFFEIGGHSLRATALI 3838 Query: 2196 NELQKLYPGKIQITDIFSYPTISRLAQFIDNQSAFAEAAV 2235 ++QK +I + D+F +PTI +LA+ I AA+ Sbjct: 3839 AKIQKQMHVQIPLRDVFRFPTIEQLARTITKTELTGYAAI 3878 Score = 1603 bits (4152), Expect = 0.0, Method: Compositional matrix adjust. Identities = 877/2246 (39%), Positives = 1313/2246 (58%), Gaps = 59/2246 (2%) Query: 11 FEKVIQKLNLKSDASRNPLFDVMFVLENLDYGLGPNEEQAKVKLIEPMAEVAKFDLTLTA 70 F K+ + L+++ + PL + L + + L E+ A L FDL Sbjct: 144 FRKMARHLSVQYNDEHMPLIHTVVSLNEI-HSLQCKEDTATDTLFH-------FDL---- 191 Query: 71 KEAGGNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGGLDMLSNQEKHLLL 130 + L Y+ L+++ + ++ H +LL+ P + ++L +K LL Sbjct: 192 --ENNGIHLKLFYNGNLYDERYINQIVSHLDQLLSVILFQPQAAIHTAEILPEAQKQKLL 249 Query: 131 NVFKGTPTDYPKDKTIHELFEEQADRTPDQLAVVCGGQALTYSELNEQANSLASVLREKG 190 F T D+ +T+++LFEEQA+RTP+ AV LTY ELNE+A+ LA LR G Sbjct: 250 FDFNDTVRDFSGSRTVYQLFEEQAERTPENAAVKFKNDHLTYRELNEKASRLARTLRNCG 309 Query: 191 VGAEAIVGIMADRSLELIIAILGTLKAGGAYLPIDPEYPADRINYMLTDSQAAMLLFQHH 250 V + +V I+ADRSLE+I++I+ KAGGAY+P+DPEYP +R+ Y+L D+ A +LL QHH Sbjct: 310 VQPDTLVAILADRSLEMIVSIIAVWKAGGAYVPLDPEYPKERLQYLLHDADADVLLVQHH 369 Query: 251 IVKDLTYAGGRLELENSELYIRETG--NPVKASLPENLAYVIYTSGTTGTPKGVMVEHRN 308 + L + G ++L + Y + +PV +LAYVIYTSGTTG PKGVMVEH Sbjct: 370 LKNSLAFDGPVIDLNDEASYHADCSLLSPVAGH--SHLAYVIYTSGTTGKPKGVMVEHGG 427 Query: 309 LVNYIHWANKRYVAGEQTAFPLYSSISFDLTVTSIYTPLISGNTIVIYDGEDKALLTRTI 368 +VN + W + + FD + + + PLISG T+ + E+ T Sbjct: 428 IVNSLQWKKAFFKHSPADRVLVLYPYVFDAFILNFFGPLISGATLHLLPNEENK---ETF 484 Query: 369 AEENKVNIVKLT--PTHLRLLEDM--DLSRSS---IRTFIVGGEDLKIKVAEKIHRAFDG 421 A +N + ++T T RLL+ M ++R ++ +VGGE L+ EK+H + Sbjct: 485 AIQNAIKQERITHFSTSPRLLKTMIEQMNREDFIHVQHVVVGGEQLETDTVEKLH-SLQP 543 Query: 422 RIEIYNEYGPTEATVGCMIYKYNAERDKGTSVSIGIPADNTQLYIVGSRMELLPVGVAGE 481 RI I NEYGPTE +V + ++ + ++IG P N Q YI+G+ ++ P+G+ GE Sbjct: 544 RIRINNEYGPTENSV---VSTFHPVQSADEQITIGSPVANHQAYILGAHHQIQPIGIPGE 600 Query: 482 LCIGGDGVARGYLHKEALTAEKFVDHPFNAGSKLYKTGDMARWLSDGTVEYLGRMDNQVK 541 L +GG GVARGYL++ LT EKFV+H G K+YKTGD+ARWL DG +EYLGR+D+QVK Sbjct: 601 LYVGGAGVARGYLNRPELTEEKFVEHLHVPGQKMYKTGDLARWLPDGRIEYLGRIDHQVK 660 Query: 542 IRGYRIETGEIENRLLQMPDITEAVVVARTDEQGHNYLCAYVVSNKEVIASEVKGRLSKE 601 IRGYRIE GE+E + + ++ EA VVAR D G L AY V + A++ + LS+E Sbjct: 661 IRGYRIEIGEVEAAMFNLENVREAAVVAREDADGAKQLYAYYVGEPSLTAAQFREELSRE 720 Query: 602 LPNYMVPGFTVQIAKLPLSSNGKVDIKALPAVDISEMLAASYEAPNNKVEEILVDVWQRV 661 LPNYM+P + + ++PL+SNGK+D+KALPA D + Y AP N +EE+L +WQ V Sbjct: 721 LPNYMIPSRFIPLERIPLTSNGKIDLKALPAADENTRAENEYIAPRNTIEELLASIWQEV 780 Query: 662 LNIEPIGTNYNYYEMGGDSIKSILIVSALREHGLRLEVKDLMQYPSIKELAGYVKHEDVQ 721 L E IG N+++ GGDSIKSI + S L + G ++++K L ++PSI EL+ +V Sbjct: 781 LGAERIGILDNFFDFGGDSIKSIQVSSRLYQAGYKVDMKHLFKHPSIAELSQFVAPVSRV 840 Query: 722 APQEAVEGSVPFLPVQQWFFEQGLPQENHYNQAFMFYRKEGLDEEILRKAVVAILVHHDA 781 A Q V G P+Q WFFEQ +P +HYNQA M Y EG E LR+ + I HHDA Sbjct: 841 ADQGEVNGGTKLTPIQHWFFEQKMPHAHHYNQAVMLYSAEGFKEGPLRRTMERIASHHDA 900 Query: 782 LRMVYKRTPDGITQWNRSADCAGAAFTLDVYDLRGQ-DEKRSIPALSDELQKGLDLEEGL 840 LRM++++TPDG D F L+V + +G+ D ++I ++E+Q + L++G Sbjct: 901 LRMIFEKTPDGYAPRITGTD-ESELFHLEVMNYKGETDPAQAIADKANEIQSSMVLDKGP 959 Query: 841 LVKLGLFKTSLGDHLLVAVHHLVIDGVSWRILIADLETAYRNIAAGAAASLPPKTASYRS 900 L+KLGLF+ GDHLL+A+HHL+IDGVSWRIL+ D + Y LP KT S+ Sbjct: 960 LMKLGLFQCPDGDHLLIAIHHLLIDGVSWRILLEDFASGYEQAERRQTIQLPQKTDSFPF 1019 Query: 901 WAQKLKEYASGKVLLKEAEYWKGITNTGSGPLPKDFGEENRGCGERMEVSLNFSKEQTAK 960 WA +L +YA+ + +E YW +++ PLPKD E + EV++ ++KE+T + Sbjct: 1020 WADQLSKYAAETDMEEEIAYWTELSSIKPQPLPKDTISEGSLLRDSEEVTIQWTKEETEQ 1079 Query: 961 LLRNCNTAYNTQINDVLLCSLGLAFKEWGGMDQLLVSLEGHGREEIFQGVSIDRTIGWFT 1020 LL+ N AYNT IND+LL SLGLA +W G + ++V+LEGHGRE I I RTIGWFT Sbjct: 1080 LLKQANRAYNTDINDLLLTSLGLAVHKWTGTEDIVVNLEGHGREPIIPDADISRTIGWFT 1139 Query: 1021 TIFPVVLDMTRSHDLAYSLKRTKEMLRHVPHKGIGYGIWKYLADGNKELRAFE--PEVSF 1078 + +PVVL M +L+ +K KE LR +P KG+ Y I KY++ G+ E + + PE+SF Sbjct: 1140 SQYPVVLRMEAGKNLSQRIKIVKEGLRRIPDKGMNYSIIKYIS-GHPEADSLQLKPEISF 1198 Query: 1079 NYLGEFGREAGSSLLEFSRLSSGASISIDNNKLKGIDINGLIMEGELELVFSYSTLEYTR 1138 NYLG+F ++ L S S+G S++ + + +D+NG+I EG L L SYS+ +Y R Sbjct: 1199 NYLGQFDQDLKHQALRISPFSTGLSMNENQERTAVLDLNGMIAEGTLSLTLSYSSKQYER 1258 Query: 1139 ETVAQLTAAYHTSLLQVIDHCAHRQTAEKTPWDYGDPDLSLEDLDTLLACGQEI---EKI 1195 T+AQ SL +VI HC RQ TP D D+S+++L+ LL +E+ E I Sbjct: 1259 STMAQFARGLKESLQEVIAHCVSRQQTSLTPSDILLKDISIDELEQLLEQTRELGEAENI 1318 Query: 1196 HSLSPMQEGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEILRTAFFY 1255 + L+PMQ+GM+++++ D S YF+Q+ ++ G L ++ + L+ L+ KY+I RT F+ Sbjct: 1319 YPLTPMQKGMLFHSLFDPNSGAYFQQTMFDLHGDLEIDSFSKSLDGLSQKYDIFRTNFYR 1378 Query: 1256 HDIKKFKQAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDRSNPFDLEQDCLLRVAVL 1315 + Q + K +K+ + D+ ++ + I+++ +D+ FDLE+ L+R+ +L Sbjct: 1379 GWKDQPLQIIFKTKKIGFQFNDLREMKESQKEAMIQKYAREDKMRGFDLEKGALMRLFIL 1438 Query: 1316 KTDTGNFKVVYSFHHIIMDGWSAGIILQEVIAQYKARLQEAELKQEKAVPYSDYLDWLDH 1375 +TD ++ ++SFHHI+MDGW +I +E+ Y A LQ+ + +Q PYS Y++WL Sbjct: 1439 RTDEKTYRFIWSFHHILMDGWCLPLITKEIFENYFALLQQKQPEQSSITPYSQYIEWLGR 1498 Query: 1376 QDKAAALDYWQSYLEAYESGTVIPELQHQEKGFMHQQERTSLDAQA--TAKLKSLAEANG 1433 QD A YW YLE YE T +P+ H + + E+ + D + T+K+K A + Sbjct: 1499 QDAKEAAAYWDQYLEGYEEQTGLPKDHHAAEDGRYVPEKVTCDISSDLTSKMKRTAGKHH 1558 Query: 1434 ITLSSVIQTAWGVVLQKYSNTHDVVFGSVVSGRPSDIKGIERMVGLCINTVPVRVTGGDQ 1493 +TL++++QTAW V+LQKY+ + DVVFGSVVSGRP+ I +E M+GL INT+PVR Sbjct: 1559 VTLNTLLQTAWAVLLQKYNRSRDVVFGSVVSGRPAGIPNVETMIGLFINTIPVRFRCEAG 1618 Query: 1494 LSFIALAKKLNKDFIHANAFSFCQLAEIQALSPMKNNLINHVVVYENYPVDQSLADLQEA 1553 +F L K+ + + + F L +IQA + K +LI H++++ENYPVDQ + + Sbjct: 1619 TTFAELMKEAQERAVASQKFETHPLYDIQARTTQKQDLITHLMIFENYPVDQYMESIGRQ 1678 Query: 1554 EGREVKITAAQGFEQTNYDLEILIAPGRTLQIKITYNGCKYSRDVINALMDNLMHVLSCA 1613 G + I+ Q EQTNYD + + PG + I YN Y R I + ++ M +L Sbjct: 1679 NGTSITISNVQMEEQTNYDFNLTVIPGDEMNISFEYNANVYERASIERVREHFMQILHQV 1738 Query: 1614 VSNPDQAAESIDMVSEQERNKLLYELNCTGTAYAKEKTIAQLFEEQAERTPEAIALEFHG 1673 V++ D + ++++E ER LL LN T + + + QLFEEQ++RTP+ A+ Sbjct: 1739 VTDADIRVDQAELLTEGERRTLLQTLNDTAAPFP-QTPVHQLFEEQSQRTPDQAAVIDKD 1797 Query: 1674 TVLSYRELNKRANQLARVLRRNSVGANVIVPILVKRSLNLLVGILGILKAGGGYLPLDTD 1733 L+Y ELNKRAN+LAR LR V + V I+ + S+ +VGIL +LK+GG Y+P+D + Sbjct: 1798 RQLTYGELNKRANRLARTLRAKGVQTDQPVAIITRNSIESVVGILAVLKSGGAYVPIDPE 1857 Query: 1734 YPVDRIHYMLQDSQASLLLTEKGLAAPLGLNEAVTILDIGSKQIQDEDDSNLQSITKADD 1793 YP DRI YML DSQA ++L ++ + L +LD S Q D S+L I+ Sbjct: 1858 YPQDRIRYMLDDSQAGIVLMQRDVRKQLAYEGVTVLLDDESSYHQ--DGSDLAPISDVSH 1915 Query: 1794 LAYVLYTSGSTGNPKGVAVEQRGVHNFIKGITDRISFTEDKIILSVTTCSFDIFGLESLL 1853 LAYV+YTSGSTG PKGV +E G+ N+I + E ++ SFD+ Sbjct: 1916 LAYVIYTSGSTGRPKGVLIEHGGLTNYIWWAKEVYVKGEKANFPLYSSISFDLTVTSIFT 1975 Query: 1854 PLTRGLKVVIASEEEQKDPHLLNKVILDSEVNTIQLTPSRLKLMLNCSNTAESFKKLKLM 1913 PL G +++ E++ LL ++ D V+ I+LTP+ L++ L N A+ ++ M Sbjct: 1976 PLVTGNAIIVYDGEDKTA--LLESIVRDPRVDIIKLTPAHLQV-LKEMNIADQ-TAVRRM 2031 Query: 1914 MIGGEGFPKDLLVQLQKFTDSR--IYNMYGPTETTIWSTVKEL----THENSVNVGKPIA 1967 ++GGE L + + + R I N YGPTET + + SV +G A Sbjct: 2032 IVGGENLSTRLARSIHEQFEGRIEICNEYGPTETVVGCMIYRYDAAKDRRESVPIGTAAA 2091 Query: 1968 NTQVYIVDQAGHLAPIGVAGELCIAGDGVARGYLHKEELTASKFVDNPFMQGTKMYTTGD 2027 NT +Y++D+ APIGV GE+ I+G GVARGYL++ ELTA KFVD+PF G KMY TGD Sbjct: 2092 NTSIYVLDENMKPAPIGVPGEIYISGAGVARGYLNRPELTAEKFVDDPFEPGAKMYKTGD 2151 Query: 2028 LARWLPNGELDVIGRLDNQVKIGGYRIELGEIESVAARHDKITQCVVAGQPNSLGSQDLV 2087 LA+WL +G ++ GR+D QVKI GYRIELGEIE+ + + I + VV + + G + L Sbjct: 2152 LAKWLADGNIEYAGRIDEQVKIRGYRIELGEIEAALLQEEVIKEAVVTAREDVHGFKQLC 2211 Query: 2088 LYFVAAEKISTSELVNFLSPVLPKYMMPQMYIQIDEIPLTANGKTNLKALPKPGNVRPEL 2147 Y+V+ + + + L LS L YM+P +I++DE+PLT+NGK N K LP P + + Sbjct: 2212 AYYVSGGQTTAARLRKQLSQTLASYMVPAYFIELDEMPLTSNGKINKKGLPAP-DFELQD 2270 Query: 2148 RDDYEEAVTDLQKEIQQVWSLILNIEQVGIYDNFFEVGGNSLKIVAMYNEL-QKLYPGKI 2206 R +Y+ T ++ + W +L E V I DNFF++GG+S+K + + + L Q+ Y K+ Sbjct: 2271 RAEYKAPRTKAEEILVSAWESVLGAENVSILDNFFDLGGDSIKSIQVSSRLNQQGY--KM 2328 Query: 2207 QITDIFSYPTISRLAQFIDNQSAFAE 2232 +I D+F Y TI+ L+ I A+ Sbjct: 2329 EIKDLFQYATIAELSPHIKQNLRIAD 2354 Score = 516 bits (1328), Expect = e-143, Method: Compositional matrix adjust. Identities = 365/1185 (30%), Positives = 596/1185 (50%), Gaps = 86/1185 (7%) Query: 1 LADFEHTHYQFEKVIQKLNLKSDASRNPLFDVMFVLENLDYGLGPNEEQAKVK--LIEPM 58 L +EH Y FE +I +LN+ D SRNPLFD MFVL+N + +EQ ++ +P Sbjct: 4189 LKAYEHQDYPFEVLIDQLNIARDLSRNPLFDTMFVLQNTE------QEQLEINDVTFKPY 4242 Query: 59 AE---VAKFDLTLTAKEAGGNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKEL 115 +AKFDLTLTA E G + F+LEY + LF T++RM H+ +L+ P+ EL Sbjct: 4243 PNGHTMAKFDLTLTAVEEGAGIQFTLEYLTALFKPETIERMMGHFEQLVDSIIKQPEAEL 4302 Query: 116 GGLDMLSNQEKHLLLNVFKGTPTDYPK-DKTIHELFEEQADRTPDQLAVVCGGQALTYSE 174 L+M++ +E+ + +F T + TIH+LFE+QA+R PD AV+ G Q LTY + Sbjct: 4303 ARLNMMTKEEERDIQQLFNDTAVAEKRIPTTIHQLFEQQAERNPDHEAVMFGNQTLTYRQ 4362 Query: 175 LNEQANSLASVLREKGVGAEAIVGIMADRSLELIIAILGTLKAGGAYLPIDPEYPADRIN 234 LNE++N LA VL++KG + +V ++ DRS +II IL LKAG A+LPIDPE P R Sbjct: 4363 LNERSNQLARVLQDKGACTDQVVAVLTDRSAHMIIGILAILKAGAAFLPIDPELPEKRRA 4422 Query: 235 YMLTDSQAAMLL-FQHHIVKDLTYAGGRLELENSELYIRETGNPVKASLPEN-LAYVIYT 292 +ML DS A +LL H + L + G L L++ LY T N + S EN L YVIYT Sbjct: 4423 FMLKDSGADVLLTCAGHAIPPL-FEGEVLLLDDPLLYQGRTDN-LNLSCSENDLMYVIYT 4480 Query: 293 SGTTGTPKGVMVEHRNLVNYIHWANKRYVAGEQTAFPL---YSSISFDLTVTSIYTPLIS 349 SGTTG PKGV +EH+ + N + + Q F ++++SFD+ +++ L S Sbjct: 4481 SGTTGQPKGVQLEHKTMTNLLAYEQDH----TQLRFDRVLQFAAMSFDVCYQEMFSALSS 4536 Query: 350 GNTIVIYDGEDKALLTR--TIAEENKVNIVKLTPTHLRLLED----MDLSRSSIRTFIVG 403 G + I E K + + + + L L+LL + + I Sbjct: 4537 GGILFIIGNEAKRDIRQLNDFVRTHGIQTAFLPTAFLKLLASEKHYFEPFAECVDHIIAA 4596 Query: 404 GEDLKIKVAEKIHRAFDGR--IEIYNEYGPTEATVGCMIYKYNAERDKGTSVSIGIPADN 461 GE L +A ++ R R + ++N YGP+E V M Y + + D+ IG P N Sbjct: 4597 GEQL---IATRMLRDMLARHQVTLHNHYGPSETHVVTM-YTVDPDTDQELQ-PIGKPISN 4651 Query: 462 TQLYIVGSRMELLPVGVAGELCIGGDGVARGYLHKEALTAEKFVDHPFNAGSKLYKTGDM 521 T+++I+ L PVG+ GELCI G +ARGY ++E+LT E FV HP+++ ++YKTGD+ Sbjct: 4652 TEIFILNEAGTLQPVGIVGELCISGVSLARGYHNRESLTLETFVPHPYDSNQRMYKTGDL 4711 Query: 522 ARWLSDGTVEYLGRMDNQVKIRGYRIETGEIENRLLQMPDITEAVVVARTDEQGHNYLCA 581 AR+L +G +EY GR D+QVKIRGYR+E GE+E LL+ + EAVV+A+ + G + L A Sbjct: 4712 ARYLPEGNIEYAGRRDHQVKIRGYRVELGEVEAALLK--HVQEAVVLAKENTDGQSDLYA 4769 Query: 582 YVVSNKEVIASEVKGRLSKELPNYMVPGFTVQIAKLPLSSNGKVDIKALPAVDISEMLAA 641 Y + + + S++K +L+ ++P YM+P + +Q+ KLPL+ NGKV+ +ALP + Sbjct: 4770 YFTAEQSLSISQLKEKLAGQIPGYMIPSYFIQLEKLPLTGNGKVNRRALPMPEAGLQTGT 4829 Query: 642 SYEAPNNKVEEILVDVWQRVLNIEPIGTNYNYYEMGGDSIKSILIVSAL-REHGLRLEVK 700 Y AP +EE L+ +WQ VL ++ IG N++++GG S++ + +++ + ++ + ++ Sbjct: 4830 DYVAPRTNMEEQLICIWQDVLKVKEIGVKDNFFDLGGHSLRGMTLIAKIHKQFSKNISLR 4889 Query: 701 DLMQYPSIKELAGYVKHEDVQA----PQEAVEGSVPFLPVQQWFF--EQGLPQENHYNQA 754 ++ Q P++ E+A + + P+ + P VQ+ + Q + E YN Sbjct: 4890 EVFQCPTVGEMAQAIAEAETNGPDYIPKAKAKDVYPVSSVQKMVYLTTQIIGGELPYNMT 4949 Query: 755 FMFYRKEGLDEEILRKAVVAILVHHDALRMVYKRTPDGITQWNRSADCAGAAFTLDVYDL 814 + + L L A ++ H+ LR V + + Q +S F+++ Y+ Sbjct: 4950 GILETEGKLPLNRLLTAFQRLMQGHEPLRTVVEMVREEAVQVIKSQ----VEFSMERYEA 5005 Query: 815 RGQDEKRSIPALSDELQKGLDLEEGLLVKLGLFKTSLGDHL-LVAVHHLVIDGVSWRILI 873 + + A + DL + L++ GL + H+ + +HH++ DG S I + Sbjct: 5006 TADEVEECFRAFV----RPFDLSQAPLLRAGLIELEQDLHIFMFDMHHIITDGASMNIFV 5061 Query: 874 ADLETAYRNIAAGAAASLPPKTASYRSWAQKLKEYASGKVLLKEAEYWKGITNT--GSGP 931 L Y L P Y+ + + + + + + EYW G+ + S Sbjct: 5062 EKLIQLY------DGKELAPLRIQYKDFTEWKHQKEQRERIKSQEEYWLGVFHEELPSFE 5115 Query: 932 LPKDFGEENRGC--GERMEVSLNFSKEQTAKLLRNC--NTAYNTQINDVLLCSLGLAFKE 987 LPKDF G+R +L+ + Q K L +TAY +L + + + Sbjct: 5116 LPKDFARPPVRSFDGKRHNFTLDKTVTQGIKQLEELTGSTAYM-----ILFSAYSILLAK 5170 Query: 988 WGGMDQLLVSLEGHGREEIFQGVSIDRTIGWFTTIFPV-VLDMTRSHDLAYSLKRTKEML 1046 + G D ++V GR ++ IG F + M L Y + + ML Sbjct: 5171 YSGQDDIVVGTPIAGRPH----ADLEPIIGMFVNTLAIRTAPMAEKTFLDYITETKETML 5226 Query: 1047 RHVPHKGIGYGIWKYLADGNKELRAFEPEVSFNYLGE---FGREAGSSLLEFSRLSSGAS 1103 + H+ +Y + E + ++S N L + + + +E L+ Sbjct: 5227 KAFEHQ-------EYPFEELVEKLGVKRDLSRNPLFDTMFVLQNTEQTDIEVDSLAVRPY 5279 Query: 1104 ISIDNNKLKGIDINGLIMEGELELVFSYSTLEYTRETVAQLTAAY 1148 + + +N LI + E++ F Y T + ++T+A L Y Sbjct: 5280 EQTETAAKFDLQLNFLIDQDEIQGSFDYCTKLFKKKTIAVLAKDY 5324 Score = 504 bits (1298), Expect = e-140, Method: Compositional matrix adjust. Identities = 330/1010 (32%), Positives = 531/1010 (52%), Gaps = 60/1010 (5%) Query: 29 LFDVMFVLENLDYGLGPNEEQAKVKLIE------PMAEVAKFDLTLTAKEAGGNLDFSLE 82 L D + + EN Y +G E+ E M E + +DL + G L Sbjct: 3165 LIDHIMIFEN--YPIGQQAEETGHHGTELNITNFHMQEHSHYDLNVVVI-PGKQLAVHFG 3221 Query: 83 YSSRLFNKATVQRMGEHYARLLAEAAANPDKELGGLDMLSNQEKHLLLNVFKGTPTDYPK 142 ++ + K+ V+R+ H+ +L+ + P ++ L++L+ QEK LL+ F+ YP+ Sbjct: 3222 FNENEYEKSEVERLRGHFEKLMQQVLRQPSVKIEDLELLTQQEKEYLLSRFQSNDMHYPR 3281 Query: 143 DKTIHELFEEQADRTPDQLAVVCGGQALTYSELNEQANSLASVLREKGVGAEAIVGIMAD 202 +KTIHELFEEQA RTPD AVV G+ TY ELN +AN LA L+ KGV A+ +VGIM + Sbjct: 3282 EKTIHELFEEQAHRTPDNTAVVFEGKQFTYEELNRRANQLARTLQAKGVQADQLVGIMTE 3341 Query: 203 RSLELIIAILGTLKAGGAYLPIDPEYPADRINYMLTDSQAAMLLFQHHIVKDLTYAGGRL 262 RSLE+++ ILG LKAGGAYLPIDP+ P++RI Y+L DS ++LL+ + D+ ++G + Sbjct: 3342 RSLEMVVGILGVLKAGGAYLPIDPDSPSERIRYILNDSSISVLLYCGKLQDDIGFSGTCI 3401 Query: 263 ELENSELYIRETGNPVKASLPENLAYVIYTSGTTGTPKGVMVEHRNLVNYIHWANKRYVA 322 +L Y + + + LAY IYTSGTTG PKG ++EHR +++ I +++ + Sbjct: 3402 DLMEEHFYHEKDSSLALSYQSSQLAYAIYTSGTTGKPKGTLIEHRQVIHLIEGLSRQVYS 3461 Query: 323 G--EQTAFPLYSSISFDLTVTSIYTPLISGNTIVIYDGE---DKALLTRTIAEENKVNIV 377 + + + FD +V +Y L+SG+T+ I E D A L R ++ ++I Sbjct: 3462 AYDAELNIAMLAPYYFDASVQQMYASLLSGHTLFIVPKEIVSDGAALCRYY-RQHSIDIT 3520 Query: 378 KLTPTHLRLL-EDMDLSRSSIRTFIVGGEDLKIKVAEKIHRAFD---GRIEIYNEYGPTE 433 TP HL+LL DL +++ ++GGE L K+ + F I N YGPTE Sbjct: 3521 DGTPAHLKLLIAAGDLQGVTLQHLLIGGEALSKTTVNKLKQLFGEHGAAPGITNVYGPTE 3580 Query: 434 ATVGCMIYKYNAERDKGTS----VSIGIPADNTQLYIVGSRMELLPVGVAGELCIGGDGV 489 V ++ D V IG P ++YI+ S+ L P GV GEL I GDGV Sbjct: 3581 TCVDASLFNIECSSDAWARSQNYVPIGKPLGRNRMYILDSKKRLQPKGVQGELYIAGDGV 3640 Query: 490 ARGYLHKEALTAEKFVDHPFNAGSKLYKTGDMARWLSDGTVEYLGRMDNQVKIRGYRIET 549 RGYL+ LT EKFV PF ++Y+TGD+AR L DG +EY+GR+D+QVKI+G+RIE Sbjct: 3641 GRGYLNLPELTDEKFVADPFVPEDRMYRTGDLARLLPDGNIEYIGRIDHQVKIQGFRIEL 3700 Query: 550 GEIENRLLQMPDITEAVVVARTDEQGHNYLCAYVVSNKEVIASEVKGRLSKELPNYMVPG 609 GEIE+ +L +PDI EA A D YLC Y ++K + SE++ R+++ LP YM+P Sbjct: 3701 GEIESVMLNVPDIQEAAAAALKDADDEYYLCGYFAADKTIQISELRKRMARHLPGYMIPA 3760 Query: 610 FTVQIAKLPLSSNGKVDIKALPAVDISEMLAASYEAPNNKVEEILVDVWQRVLNIEPIGT 669 VQ+ K+PL+ NGK++ + LPA Y P E L +W+ VL +E +G Sbjct: 3761 HFVQLDKMPLTPNGKLNRQLLPAPVKKRDSGIEYVPPQTSAEIQLTAIWEDVLGLEQVGI 3820 Query: 670 NYNYYEMGGDSIKSILIVSAL-REHGLRLEVKDLMQYPSIKELAGYVKHEDVQ--APQEA 726 +++E+GG S+++ +++ + ++ +++ ++D+ ++P+I++LA + ++ A A Sbjct: 3821 RDHFFEIGGHSLRATALIAKIQKQMHVQIPLRDVFRFPTIEQLARTITKTELTGYAAIPA 3880 Query: 727 VEGSVPFLPVQQWFFEQGLPQENH-------YNQAFMFYRKEGLDEEILRKAVVAILVHH 779 +E P+ PV ++ L NH YN + + LD + L++A +++ H Sbjct: 3881 IEKR-PYYPVSSA--QKRLYILNHLEGGELSYNMLGLMTVEGKLDRDKLQQAFRTLILRH 3937 Query: 780 DALRMVYKRTPDGITQWNRSADCAGAAFTLDVYDLRGQDEKRSIPALSDELQKGLDLEEG 839 ++LR +K Q+ AAF + Y Q E+ + + L+E Sbjct: 3938 ESLRTGFKMADGEPVQYV----LDHAAFEAEWY----QGEEDDADLYIRQFIRPFHLDEP 3989 Query: 840 LLVKLGLFKTSLGDHLLV-AVHHLVIDGVSWRILIADLETAYRNIAAGAAASLPPKTASY 898 L+++GL + +L+ +HH++ DG S +LI + Y +LPP Y Sbjct: 3990 PLLRVGLIELQPDRGILMFDMHHIISDGTSMSVLIKEFIRIYE------GETLPPLRIQY 4043 Query: 899 RSWAQKLKEYASGKVLLKEAEYWKGITNTGSGP---LPKDFGEENRG--CGERMEVSLNF 953 + +A A + + K+ YW + +G P LP D+ + G M +L+ Sbjct: 4044 KDYAVWQTGEARLQQIQKQEAYWLELY-SGDVPVLHLPADYIRPSARDFAGATMHFTLD- 4101 Query: 954 SKEQTAKLLRNCNTAYNTQINDVLLCSLGLAFKEWGGMDQLLVSLEGHGR 1003 +Q + L+ + + + VLL S L ++ G + ++V GR Sbjct: 4102 --KQKSDGLKQLASQTESTLYMVLLASYTLLLSKYSGQEDIIVGSPIAGR 4149 Score = 476 bits (1224), Expect = e-131, Method: Compositional matrix adjust. Identities = 320/1039 (30%), Positives = 534/1039 (51%), Gaps = 61/1039 (5%) Query: 1211 VDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEILRTAFFYHDIKKFKQAVLKERK 1270 ++ G +Y + +EG L+ + L L ++E LRT F D + Q VL Sbjct: 3902 LEGGELSYNMLGLMTVEGKLDRDKLQQAFRTLILRHESLRTGFKMADGEPV-QYVLDHAA 3960 Query: 1271 LRIHY----EDISSRSMQEQSSYIEQFKVQDRSNPFDLEQDCLLRVAVLKTDTGNFKVVY 1326 + ED + YI QF PF L++ LLRV +++ +++ Sbjct: 3961 FEAEWYQGEED-------DADLYIRQF-----IRPFHLDEPPLLRVGLIELQPDRGILMF 4008 Query: 1327 SFHHIIMDGWSAGIILQEVIAQYKARLQEAELKQEKAVPYSDYLDWLDHQDKAAALDYWQ 1386 HHII DG S ++++E I R+ E E + Y DY W + + + + Sbjct: 4009 DMHHIISDGTSMSVLIKEFI-----RIYEGETLPPLRIQYKDYAVWQTGEARLQQIQKQE 4063 Query: 1387 SY-LEAYESGTV----IPE--LQHQEKGFMHQQERTSLDAQATAKLKSLAEANGITLSSV 1439 +Y LE Y SG V +P ++ + F +LD Q + LK LA TL V Sbjct: 4064 AYWLELY-SGDVPVLHLPADYIRPSARDFAGATMHFTLDKQKSDGLKQLASQTESTLYMV 4122 Query: 1440 IQTAWGVVLQKYSNTHDVVFGSVVSGRPSDIKGIERMVGLCINTVPVRVTGGDQLSFIAL 1499 + ++ ++L KYS D++ GS ++GRP +E ++G+ +NT+ +R +F Sbjct: 4123 LLASYTLLLSKYSGQEDIIVGSPIAGRPH--ADLEPIIGMFVNTLAMRNYPEKGKTFSQY 4180 Query: 1500 AKKLNKDFIHA---NAFSF----CQLAEIQALSPMKNNLINHVVVYENYPVDQSLADLQE 1552 ++ ++ + A + F QL + LS +N L + + V +N + ++ Sbjct: 4181 LSEVKENALKAYEHQDYPFEVLIDQLNIARDLS--RNPLFDTMFVLQN-------TEQEQ 4231 Query: 1553 AEGREVKITA-AQGFEQTNYDLEIL-IAPGRTLQIKITYNGCKYSRDVINALMDNLMHVL 1610 E +V G +DL + + G +Q + Y + + I +M + ++ Sbjct: 4232 LEINDVTFKPYPNGHTMAKFDLTLTAVEEGAGIQFTLEYLTALFKPETIERMMGHFEQLV 4291 Query: 1611 SCAVSNPDQAAESIDMVSEQERNKLLYELNCTGTAYAK-EKTIAQLFEEQAERTPEAIAL 1669 + P+ ++M++++E + N T A + TI QLFE+QAER P+ A+ Sbjct: 4292 DSIIKQPEAELARLNMMTKEEERDIQQLFNDTAVAEKRIPTTIHQLFEQQAERNPDHEAV 4351 Query: 1670 EFHGTVLSYRELNKRANQLARVLRRNSVGANVIVPILVKRSLNLLVGILGILKAGGGYLP 1729 F L+YR+LN+R+NQLARVL+ + +V +L RS ++++GIL ILKAG +LP Sbjct: 4352 MFGNQTLTYRQLNERSNQLARVLQDKGACTDQVVAVLTDRSAHMIIGILAILKAGAAFLP 4411 Query: 1730 LDTDYPVDRIHYMLQDSQASLLLTEKGLAAPLGLNEAVTILDIGSKQIQDEDDSNLQSIT 1789 +D + P R +ML+DS A +LLT G A P V +LD + NL Sbjct: 4412 IDPELPEKRRAFMLKDSGADVLLTCAGHAIPPLFEGEVLLLD--DPLLYQGRTDNLNLSC 4469 Query: 1790 KADDLAYVLYTSGSTGNPKGVAVEQRGVHNFIKGITDRISFTEDKIILSVTTCSFDIFGL 1849 +DL YV+YTSG+TG PKGV +E + + N + D D+ +L SFD+ Sbjct: 4470 SENDLMYVIYTSGTTGQPKGVQLEHKTMTNLLAYEQDHTQLRFDR-VLQFAAMSFDVCYQ 4528 Query: 1850 ESLLPLTRGLKVVIASEEEQKDPHLLNKVILDSEVNTIQLTPSRLKLMLNCSNTAESFKK 1909 E L+ G + I E ++D LN + + T L + LKL+ + + E F + Sbjct: 4529 EMFSALSSGGILFIIGNEAKRDIRQLNDFVRTHGIQTAFLPTAFLKLLASEKHYFEPFAE 4588 Query: 1910 L--KLMMIGGEGFPKDLLVQLQKFTDSRIYNMYGPTETTIWS--TVKELTHENSVNVGKP 1965 ++ G + +L + ++N YGP+ET + + TV T + +GKP Sbjct: 4589 CVDHIIAAGEQLIATRMLRDMLARHQVTLHNHYGPSETHVVTMYTVDPDTDQELQPIGKP 4648 Query: 1966 IANTQVYIVDQAGHLAPIGVAGELCIAGDGVARGYLHKEELTASKFVDNPFMQGTKMYTT 2025 I+NT+++I+++AG L P+G+ GELCI+G +ARGY ++E LT FV +P+ +MY T Sbjct: 4649 ISNTEIFILNEAGTLQPVGIVGELCISGVSLARGYHNRESLTLETFVPHPYDSNQRMYKT 4708 Query: 2026 GDLARWLPNGELDVIGRLDNQVKIGGYRIELGEIESVAARHDKITQCVVAGQPNSLGSQD 2085 GDLAR+LP G ++ GR D+QVKI GYR+ELGE+E+ +H + + VV + N+ G D Sbjct: 4709 GDLARYLPEGNIEYAGRRDHQVKIRGYRVELGEVEAALLKH--VQEAVVLAKENTDGQSD 4766 Query: 2086 LVLYFVAAEKISTSELVNFLSPVLPKYMMPQMYIQIDEIPLTANGKTNLKALPKPGNVRP 2145 L YF A + +S S+L L+ +P YM+P +IQ++++PLT NGK N +ALP P Sbjct: 4767 LYAYFTAEQSLSISQLKEKLAGQIPGYMIPSYFIQLEKLPLTGNGKVNRRALPMP-EAGL 4825 Query: 2146 ELRDDYEEAVTDLQKEIQQVWSLILNIEQVGIYDNFFEVGGNSLKIVAMYNELQKLYPGK 2205 + DY T++++++ +W +L ++++G+ DNFF++GG+SL+ + + ++ K + Sbjct: 4826 QTGTDYVAPRTNMEEQLICIWQDVLKVKEIGVKDNFFDLGGHSLRGMTLIAKIHKQFSKN 4885 Query: 2206 IQITDIFSYPTISRLAQFI 2224 I + ++F PT+ +AQ I Sbjct: 4886 ISLREVFQCPTVGEMAQAI 4904 Score = 95.5 bits (236), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 99/460 (21%), Positives = 200/460 (43%), Gaps = 46/460 (10%) Query: 1195 IHSLSPMQEGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEILRTAFF 1254 ++ +S +Q+ + T + G Y L EG L + L L +E LRT Sbjct: 4923 VYPVSSVQKMVYLTTQIIGGELPYNMTGILETEGKLPLNRLLTAFQRLMQGHEPLRTV-- 4980 Query: 1255 YHDIKKFKQAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDRS--NPFDLEQDCLLRV 1312 ++ ++ ++ K ++ + SM+ + ++ + R+ PFDL Q LLR Sbjct: 4981 ---VEMVREEAVQVIKSQVEF------SMERYEATADEVEECFRAFVRPFDLSQAPLLRA 5031 Query: 1313 AVLKTDTGNFKVVYSFHHIIMDGWSAGIILQEVIAQYKARLQEAELKQEKAVPYSDYLDW 1372 +++ + ++ HHII DG S I ++++I Y + + A L+ + Y D+ +W Sbjct: 5032 GLIELEQDLHIFMFDMHHIITDGASMNIFVEKLIQLYDGK-ELAPLR----IQYKDFTEW 5086 Query: 1373 LDHQDKAAAL----DYWQSYLEAYESGTVIPE--LQHQEKGFMHQQERTSLDAQATAKLK 1426 +++ + +YW +P+ + + F ++ +LD T +K Sbjct: 5087 KHQKEQRERIKSQEEYWLGVFHEELPSFELPKDFARPPVRSFDGKRHNFTLDKTVTQGIK 5146 Query: 1427 SLAEANGITLSSVIQTAWGVVLQKYSNTHDVVFGSVVSGRPSDIKGIERMVGLCINTVPV 1486 L E G T ++ +A+ ++L KYS D+V G+ ++GRP +E ++G+ +NT+ + Sbjct: 5147 QLEELTGSTAYMILFSAYSILLAKYSGQDDIVVGTPIAGRPH--ADLEPIIGMFVNTLAI 5204 Query: 1487 RVTGGDQLSFIALAKKLNKDFIHA---NAFSFCQLAEIQALSP--MKNNLINHVVVYENY 1541 R + +F+ + + + A + F +L E + +N L + + V +N Sbjct: 5205 RTAPMAEKTFLDYITETKETMLKAFEHQEYPFEELVEKLGVKRDLSRNPLFDTMFVLQN- 5263 Query: 1542 PVDQSLADLQEAEGREVKITAAQGFEQT----NYDLEI-LIAPGRTLQIKITYNGCKYSR 1596 E EV A + +EQT +DL++ + +Q Y + + Sbjct: 5264 ---------TEQTDIEVDSLAVRPYEQTETAAKFDLQLNFLIDQDEIQGSFDYCTKLFKK 5314 Query: 1597 DVINALMDNLMHVLSCAVSNPDQAAESIDMVSEQERNKLL 1636 I L + + +LS + NP + I + + ++K L Sbjct: 5315 KTIAVLAKDYVMILSAIMRNPSIPLKDIQLSEKVNKSKHL 5354 Score = 76.6 bits (187), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 46/130 (35%), Positives = 67/130 (51%), Gaps = 3/130 (2%) Query: 1 LADFEHTHYQFEKVIQKLNLKSDASRNPLFDVMFVLENLDYGLGPNEEQAKVKLIEPMAE 60 L FEH Y FE++++KL +K D SRNPLFD MFVL+N + + V+ E Sbjct: 5226 LKAFEHQEYPFEELVEKLGVKRDLSRNPLFDTMFVLQNTE-QTDIEVDSLAVRPYEQTET 5284 Query: 61 VAKFDLTLTAKEAGGNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGGLDM 120 AKFDL L + S +Y ++LF K T+ + + Y +L+ NP L + + Sbjct: 5285 AAKFDLQLNFLIDQDEIQGSFDYCTKLFKKKTIAVLAKDYVMILSAIMRNPSIPLKDIQL 5344 Query: 121 LS--NQEKHL 128 N+ KHL Sbjct: 5345 SEKVNKSKHL 5354 >C3HA00.1 C3HA00_BACTU Phenylalanine racemase Length = 6350 Score = 1751 bits (4536), Expect = 0.0, Method: Compositional matrix adjust. Identities = 923/2254 (40%), Positives = 1410/2254 (62%), Gaps = 46/2254 (2%) Query: 1 LADFEHTHYQFEKVIQKLNLKSDASRNPLFDVMFVLENLDYGLGPNEEQAKVKLIEPMAE 60 L +E+ Y +++++KL+L+ D SR+ LFD MFVL+NLD NEE + +E Sbjct: 1345 LKAYENQDYPLDELVEKLDLQRDMSRSALFDTMFVLQNLD---TSNEEIKGLSFETYDSE 1401 Query: 61 --VAKFDLTLTAKEAGGNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGGL 118 +A FDLTL+A E + F LEY ++LF K T+ ++ EH+ +L E N + LG + Sbjct: 1402 LNIANFDLTLSAVETNNIIKFDLEYCTKLFKKETIAKISEHFVSILREITNNQEVCLGQI 1461 Query: 119 DMLSNQEKHLLLNVFKGTPTDYPKDKTIHELFEEQADRTPDQLAVVCGGQALTYSELNEQ 178 DMLS +EKH+LLN F T DYPK+KTI++LFEEQ +RTP+++AV GQ +TY ELNE+ Sbjct: 1462 DMLSGEEKHILLNEFNETYMDYPKNKTIYQLFEEQVERTPNKVAVEFEGQQVTYKELNEK 1521 Query: 179 ANSLASVLREKGVGAEAIVGIMADRSLELIIAILGTLKAGGAYLPIDPEYPADRINYMLT 238 +N +A VL +KGV E IVGIM +RSL++I+ I+G LK+G AYLPIDPEYP +RI YM+ Sbjct: 1522 SNQVARVLYDKGVHPEMIVGIMVERSLDMIVGIMGILKSGAAYLPIDPEYPEERIKYMVE 1581 Query: 239 DSQAAMLLFQHHIVKDLTYAGG----RLELENSELYIRETGNPVKASLPENLAYVIYTSG 294 DS A +L Q H+ L + ++ + + + +E N + + +LAYVIYTSG Sbjct: 1582 DSNAKFVLTQTHLYDKLHFINNECITKISINDETIKNQEQINMERRNNRNDLAYVIYTSG 1641 Query: 295 TTGTPKGVMVEHRNLVNYIHWANKRYVAGEQTAFPLYSSISFDLTVTSIYTPLISGNTIV 354 +TG PKGV+VEH +LVN +W + E+ Y +SFD ++ I+ LI+G T+ Sbjct: 1642 STGLPKGVLVEHHSLVNLCNWYVDFHKITERDRITNYLKVSFDASIGEIFPCLITGATLH 1701 Query: 355 IYDGEDKALLTRTIAEENKVNIVKLTPTHLRLLEDMDLSRS-SIRTFIVGGEDLKIKVAE 413 + G+D L + E + + ++ E L + S+R + GGE L + Sbjct: 1702 VL-GKDMRLDLDKLNEYMNSKDITVATFPSKVSEQFILQDNHSLRMLVSGGEKLILNK-- 1758 Query: 414 KIHRAFDGRIEIYNEYGPTEATVGCMIYKYNAERDKGTSVSIGIPADNTQLYIVGSRMEL 473 + R ++ N YGPTE TV + N D ++ IG P NT++YIV +L Sbjct: 1759 ------NTRYQLVNAYGPTENTVVTTSFLMNKNDD---NIPIGKPVYNTKVYIVNKYNQL 1809 Query: 474 LPVGVAGELCIGGDGVARGYLHKEALTAEKFVDHPFNAGSKLYKTGDMARWLSDGTVEYL 533 P+GV GELCI G G+ARGYL+ ALTAEKFV +PF +G K+Y+TGD+ RW+ DG VE++ Sbjct: 1810 CPIGVTGELCISGVGLARGYLNNPALTAEKFVGNPFVSGEKMYRTGDLVRWMPDGNVEFI 1869 Query: 534 GRMDNQVKIRGYRIETGEIENRLLQMPDITEAVVVARTDEQGHNYLCAYVVSNKEVIASE 593 GR+D+QVKIRGYRIE GEIE++LL+ DI E VVVA+ D++ H Y+ AY+VS K + +++ Sbjct: 1870 GRIDHQVKIRGYRIELGEIESQLLKHQDIKEVVVVAKEDKKNHTYISAYIVSEKAISSAK 1929 Query: 594 VKGRLSKELPNYMVPGFTVQIAKLPLSSNGKVDIKALPAVDISEMLAASYEAPNNKVEEI 653 ++ L KELP+YM+P + VQ+ +LPL+SN KVD KALP D S YEAP N+VE Sbjct: 1930 IREFLEKELPDYMIPSYFVQLDQLPLTSNDKVDRKALPEPDRSSQSGVEYEAPRNEVETH 1989 Query: 654 LVDVWQRVLNIEPIGTNYNYYEMGGDSIKSILIVSALREHGLRLEVKDLMQYPSIKELAG 713 LV++W+ +L IE IG N++++ GGDSIK++ IVS L L+LEVKDL P IK+L+ Sbjct: 1990 LVEIWRDILGIEDIGINHHFFVSGGDSIKALQIVSRLSRINLKLEVKDLFANPKIKDLSK 2049 Query: 714 YVKHEDVQ-APQEAVEGSVPFLPVQQWFFEQGLPQENHYNQAFMFYRKEGLDEEILRKAV 772 YVK ++ + P E V G V P+Q+W+FE+ + +H+NQ+FM +R++G D++ + + Sbjct: 2050 YVKKQNKRLKPYEIVTGEVILSPIQKWYFEKNKEELDHFNQSFMLFREDGFDQKRIERVF 2109 Query: 773 VAILVHHDALRMVYKRTPDGITQWNRSADCAGAAFTLDVYDLRG-QDEKRSIPALSDELQ 831 IL HDALRM+Y+ I Q+NR F L V+D+ G ++++ I L+ +Q Sbjct: 2110 NKILEQHDALRMIYRENDGEIIQYNRG--YKDNLFDLYVHDVEGVENKEEKIYELATNIQ 2167 Query: 832 KGLDLEEGLLVKLGLFKTSLGDHLLVAVHHLVIDGVSWRILIADLETAYRNIAAGAAASL 891 K ++ G LV L LFKT+ GDHLL+ +HHLV+DGVSWRI++ D ET Y G + Sbjct: 2168 KKSSIKNGKLVNLCLFKTNQGDHLLITIHHLVVDGVSWRIILEDFETLYSQDLRGEKLDV 2227 Query: 892 PPKTASYRSWAQKLKEYASGKVLLKEAEYWKGITNTGSGPLPKDFGEENRGCGERMEVSL 951 KT S++ ++ KL+EYAS LLKE EYW+ I NT +P+ ++ VS+ Sbjct: 2228 GFKTESFKEFSSKLREYASNNKLLKEKEYWQEIANTEVAFIPRKKELKSDTFENSKTVSI 2287 Query: 952 NFSKEQTAKLLRNCNTAYNTQINDVLLCSLGLAFKEWGGMDQLLVSLEGHGREEIFQGVS 1011 + +KE+T LLR N AYNT+IND+LL SL L +E + + +++EGHGRE+I + V Sbjct: 2288 SLNKEKTISLLRKSNRAYNTEINDILLTSLLLGAREITSENCIKINMEGHGREDILENVD 2347 Query: 1012 IDRTIGWFTTIFPVVLDMTRSHDLAYSLKRTKEMLRHVPHKGIGYGIWKYLADGNKELRA 1071 I RT+GWFTT++PV++D+ DLA ++K KE LR +P+KGIG+GI KYL+ L Sbjct: 2348 ISRTVGWFTTMYPVLIDLGNETDLATNIKMVKETLRKIPNKGIGFGILKYLSKEKYLLNE 2407 Query: 1072 FEPEVSFNYLGEFGREAGSSLLEFSRLSSGASISIDNNKLKGIDINGLIMEGELELVFSY 1131 + +SFNYLGE + + S+ S G +I ++ I+IN +I+ EL + ++ Sbjct: 2408 QKAPISFNYLGEMDNDVNRNEFSESKFSYGETIGGKISRNNSIEINSIIINNELVINTTF 2467 Query: 1132 STLEYTRETVAQLTAAYHTSLLQVIDHCAHRQTAEKTPWDYGDPDLSLEDLDTLLACGQ- 1190 + LE+ T+ +L + SL +IDHC + EKTP+DYGD L+L +L + + Sbjct: 2468 NELEFDELTIRKLNDKFKESLETIIDHCVSQIEVEKTPYDYGDTKLTLSELKDIKEKYKD 2527 Query: 1191 -EIEKIHSLSPMQEGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEIL 1249 EIEKI+ L+ MQ+GM+++ + + S YFEQ+ ++I GY++VEIL N++ +YEIL Sbjct: 2528 FEIEKIYPLANMQKGMLFHALENKNSKAYFEQTVMDITGYVDVEILKTSFNKIMQRYEIL 2587 Query: 1250 RTAFFYHDIKKFKQAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDRSNPFDLEQDCL 1309 R +F Y + + +Q ++ +R++ + Y DIS R E+ +I+ ++ +D F+L +D L Sbjct: 2588 RASFEYEIVGEPRQIIIADREIGVQYCDISERGTIEKELFIKNYREEDTEKGFNLSKDTL 2647 Query: 1310 LRVAVLKTDTGNFKVVYSFHHIIMDGWSAGIILQEVIAQYKARLQEAELKQEKAVPYSDY 1369 +RV +++TD +K+V+S HHI++DGW GI+L E+ Y + E + E+ PYSDY Sbjct: 2648 MRVCLIRTDENLYKLVWSHHHILLDGWCLGIVLGELFTVYGKLINGEEYELEETKPYSDY 2707 Query: 1370 LDWLDHQDKAAALDYWQSYLEAYESGTVIPELQ--HQEKGFMHQQERTSLDAQATAKLKS 1427 + WL+ QDK YW+ YL+ YE IP+LQ ++ +++ + T K+ Sbjct: 2708 IKWLEEQDKEEGKSYWEQYLDGYEEKAQIPKLQITKNNSEYLRREKVIEFSNELTNKITQ 2767 Query: 1428 LAEANGITLSSVIQTAWGVVLQKYSNTHDVVFGSVVSGRPSDIKGIERMVGLCINTVPVR 1487 LA N +T ++V Q+ WG++L KY+NT +VVFG++VSGR + + GIE+M+GL IN +P R Sbjct: 2768 LANRNSVTFNTVFQSIWGIILAKYNNTDEVVFGTIVSGREAPVDGIEKMIGLFINAIPTR 2827 Query: 1488 VTGGDQLSFIALAKKLNKDFIHANAFSFCQLAEIQALSPMKNNLINHVVVYENYPVDQSL 1547 + G F + + + I +N +++ LAE+QA+S +KN+LI+H++V+ENY VD+ + Sbjct: 2828 INLGKNQKFKEVLTVVQSEAIASNNYNYMNLAEVQAMSKLKNDLIDHIIVFENYAVDKRI 2887 Query: 1548 ADLQEAE-GREVKITAAQGFEQTNYDLEILIAPGRTLQIKITYNGCKYSRDVINALMDNL 1606 A ++ + G EV+ A+ EQ+NY I PG L + +TY+G Y +I+ + ++ Sbjct: 2888 AGNEKMDIGFEVEDIHAE--EQSNYSFSIAATPGEQLNLVLTYDGNIYDDKIIDNIEMHI 2945 Query: 1607 MHVLSCAVSNPDQAAESIDMVSEQERNKLLYELNCTGTAYAKEKTIAQLFEEQAERTPEA 1666 V +++ ++ ID+++E+ER LLYE N T Y KEKTI QLF+EQ ERTPE Sbjct: 2946 KKVTEQVIADENKKINEIDIIAEEERTTLLYEFNDTKVDYPKEKTIHQLFQEQVERTPEN 3005 Query: 1667 IALEFHGTVLSYRELNKRANQLARVLRRNSVGANVIVPILVKRSLNLLVGILGILKAGGG 1726 IA+ F L+Y ELN+++NQ+A +LR V +N +V I+V+RS+ ++VG++ ILKAGG Sbjct: 3006 IAVVFENKQLTYWELNEKSNQVAALLREKGVKSNTVVGIMVERSIEMIVGMMAILKAGGA 3065 Query: 1727 YLPLDTDYPVDRIHYMLQDSQASLLLTEKGLAAPLGLNEAVTILDIGSKQIQDEDDSNLQ 1786 YLP+D +YP DR YML+DS +LL ++ L T +DI ++I+D NL Sbjct: 3066 YLPIDPEYPEDRRRYMLEDSGIEILLKQENKQVDYDL----TCIDINVQKIKDRFTENLP 3121 Query: 1787 SITKADDLAYVLYTSGSTGNPKGVAVEQRGVHNFIKGITDRISFTEDKIILSVTTCSFDI 1846 S+ K+ D+AY++YTSGSTG PKGV V + + N + + +++ I L + + SFD Sbjct: 3122 SLNKSADMAYIIYTSGSTGKPKGVMVNHKSILNTLCWRIESYQYSDSDITLQMPSFSFDS 3181 Query: 1847 FGLESLLPLTRGLKVVIASEEEQKDPHLLNKVILDSEVNTIQLTPSRLKLMLNCSNTAES 1906 + L G K+++ + +N +I +++V + PS +LN + + Sbjct: 3182 SVEDIFTTLLSGGKLILIEDIRMNFSKFIN-IIQNNKVTNLLAVPSYYNNLLNTID--KP 3238 Query: 1907 FKKLKLMMIGGEGFPKDLLVQ-LQKFTDSRIYNMYGPTETTIWSTVKELTHEN-SVNVGK 1964 L+ + I GEGF ++L+ + QK +++N YGPTE ++ ST+ EL E+ V +GK Sbjct: 3239 LLDLRFVTIAGEGFNENLITKHFQKIPHVKLFNEYGPTENSVCSTICELKQEDQKVLIGK 3298 Query: 1965 PIANTQVYIVDQAGHLAPIGVAGELCIAGDGVARGYLHKEELTASKFVDNPFMQGTKMYT 2024 PI+N +VYI+D +L P+GVAGELC++G+G+ARGYL++ ELTA KFV NPF+ G +MY Sbjct: 3299 PISNNRVYILDMENNLVPLGVAGELCVSGEGLARGYLNRPELTAEKFVPNPFIPGERMYR 3358 Query: 2025 TGDLARWLPNGELDVIGRLDNQVKIGGYRIELGEIESVAARHDKITQCVVAGQPNSLGSQ 2084 TGDLAR LPNG ++ +GR+D+QVKI G+RIELGE+E+ + +I + VV + ++ G Sbjct: 3359 TGDLARLLPNGNIEFLGRIDHQVKIRGFRIELGEVENQLFKQKEIKEAVVIAREDNNGQP 3418 Query: 2085 DLVLYFVAAEKISTSELVNF---LSPVLPKYMMPQMYIQIDEIPLTANGKTNLKALPKPG 2141 L YF + + S+L L+ LP+YM+P ++Q+D++PLTANGK + KALP+P Sbjct: 3419 YLCAYFTSETRKKESKLQEIRKDLAQELPEYMIPAFFVQLDKLPLTANGKVDRKALPEPD 3478 Query: 2142 NVRPELRDDYEEAVTDLQKEIQQVWSLILNIEQVGIYDNFFEVGGNSLKIVAMYNELQKL 2201 + +YE ++++ + +W IL +E++GI +FFE+GG+SLK M +++ K Sbjct: 3479 E-SAVVGVEYEAPRNEVEERLVSIWQEILGVEKIGINQHFFEIGGHSLKATTMVSKIHKE 3537 Query: 2202 YPGKIQITDIFSYPTISRLAQFIDNQSAFAEAAV 2235 +I + IF PTI + +FID+ A++ Sbjct: 3538 LMVEIPLRQIFQTPTIKGIGEFIDSTKESVYASI 3571 Score = 1680 bits (4350), Expect = 0.0, Method: Compositional matrix adjust. Identities = 907/2265 (40%), Positives = 1382/2265 (61%), Gaps = 75/2265 (3%) Query: 1 LADFEHTHYQFEKVIQKLNLKSDASRNPLFDVMFVLENLDY------GLGPNEEQAKVKL 54 L +E+ Y F+++++KL+LK D SR+ LFD M VL+N DY GL + Q K Sbjct: 3882 LKAYENQDYPFDELVEKLDLKRDMSRSALFDTMLVLQNFDYDDFEIQGLTFSPYQMK--- 3938 Query: 55 IEPMAEVAKFDLTLTAKEAGGNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKE 114 A V+KFDLTLTA E ++ L Y ++LF K TV+R+ +H ++ E P++ Sbjct: 3939 ----AHVSKFDLTLTAVEEERSIKCVLNYRTKLFKKETVERLAKHLIQVFKEIIEKPEQS 3994 Query: 115 LGGLDMLSNQEKHLLLNVFKGTPTDYPKDKTIHELFEEQADRTPDQLAVVCGGQALTYSE 174 + + +LS +E +LL K T DYPKDKTI +LFEEQ RTP +AVV Q LTY E Sbjct: 3995 IQDIMLLSEEEVQMLLQDDKDTKADYPKDKTISQLFEEQVKRTPHHVAVVFKNQKLTYLE 4054 Query: 175 LNEQANSLASVLREKGVGAEAIVGIMADRSLELIIAILGTLKAGGAYLPIDPEYPADRIN 234 LNE+AN +A +L+EKG VG++ + SLE+II I+ LKAG YLPIDPE R N Sbjct: 4055 LNERANQMARLLQEKGAKPGITVGMLVEESLEMIIGIMAVLKAGATYLPIDPEQLDKRTN 4114 Query: 235 YMLTDSQAAMLLFQHHIVKDLTYAGGRLELENSELYIRETGNPVKASLPENLAYVIYTSG 294 +L DS A++L+ + + L + + +E+ + R+T N + + AY+IYTSG Sbjct: 4115 VILKDSNASLLIVKGERKETLQFNAEVISMEDDSIKERDTSNLLVNYKWNHNAYIIYTSG 4174 Query: 295 TTGTPKGVMVEHRNLVNYIHWANKRYVAGEQTAFPLYSSISFDLTVTSIYTPLISGN--- 351 +TGTPKGV V+H N+VNY+ W K E L SS +FDL TS+Y+ L++G Sbjct: 4175 STGTPKGVCVQHNNVVNYMTWFTKEANLKETDKAMLVSSYAFDLGYTSLYSSLLNGCELH 4234 Query: 352 --TIVIYDGEDKALLTRTIAEENKVNIVKLTPTHLRLL-EDMDLSRS----SIRTFIVGG 404 T +Y KAL EE ++ +KLTP+ +L D S + ++R ++GG Sbjct: 4235 LVTKEVYTNAQKAL---QYIEEQGISYLKLTPSLFNVLVNDPSFSNNQSCKTLRLVVLGG 4291 Query: 405 EDLKIKVAEKIHRAFDGRIEIYNEYGPTEATVGCM--IYKYNAERDKGTSVSIGIPADNT 462 E + E + + + N YGPTEAT+G + + +Y+ IG P N Sbjct: 4292 EKINPIDVETFYTHYPNH-AVMNHYGPTEATIGSVYQVIEYDTMAAFKECPVIGRPIQNM 4350 Query: 463 QLYIVGSRMELLPVGVAGELCIGGDGVARGYLHKEALTAEKFVDHPFNAGSKLYKTGDMA 522 + Y+V +M+L+P GV GELC+ GDGVA GYL++ LT EKFV +PF K+Y+TGD+A Sbjct: 4351 KAYVVDQQMKLVPEGVYGELCLSGDGVASGYLNRADLTEEKFVQNPFEPNKKMYRTGDLA 4410 Query: 523 RWLSDGTVEYLGRMDNQVKIRGYRIETGEIENRLLQMPDITEAVVVARTDEQGHNYLCAY 582 R LSDG +E GR+D QVKIRGYRIET EI+ L++ I EA V+ R + YLCAY Sbjct: 4411 RRLSDGRIELAGRIDGQVKIRGYRIETEEIKRHLVKHEQIKEAFVIDREGQDERRYLCAY 4470 Query: 583 VVSNKEVIASEVKGRLSKELPNYMVPGFTVQIAKLPLSSNGKVDIKALPAVDISEMLAAS 642 + S +++ E++ L E+P YM+P + VQ+ ++PL++NGKVD KALP D+ + Sbjct: 4471 ITSQRDLSFEELRAYLKVEIPEYMIPSYFVQMERIPLTANGKVDEKALPEPDVGK--GVD 4528 Query: 643 YEAPNNKVEEILVDVWQRVLNIEPIGTNYNYYEMGGDSIKSILIVSALREHGLRLEVKDL 702 YE P N+VEE LV VW+ +L ++ IG ++N++ GGDSIK++ I+S L G+ LE+KDL Sbjct: 4529 YEKPRNQVEEKLVKVWEDILGVKSIGISHNFFASGGDSIKALQIISRLSREGITLEMKDL 4588 Query: 703 MQYPSIKELAGYVKHEDVQAPQEAVE-GSVPFLPVQQWFFEQGLPQENHYNQAFMFYRKE 761 YP IK L+ YV E +Q +E G V P+Q+ +F G NHYN A M YRK+ Sbjct: 4589 FTYPEIKFLSNYVNIETIQEGSYEIETGDVLLTPIQKAYFMNGKEDVNHYNHAVMLYRKD 4648 Query: 762 GLDEEILRKAVVAILVHHDALRMVYKRTPDGITQWNRSADCAGAAFTLDVYDLRGQDEKR 821 G EE++++ + AI VHHDALRM+YK + + Q+NR + F VYD+ +D Sbjct: 4649 GFREEMIQEVMEAIFVHHDALRMIYKEENNEVLQFNREVE--KNQFGFYVYDVSREDNPD 4706 Query: 822 -SIPALSDELQKGLDLEEGLLVKLGLFKTSLGDHLLVAVHHLVIDGVSWRILIADLETAY 880 I L+ LQK +D++EG LV + FKT++GDHLL+ +HHLV+DG+SWR+L D Y Sbjct: 4707 VKIQELATILQKKIDIQEGPLVNVAQFKTNVGDHLLLIIHHLVVDGISWRVLFEDFALGY 4766 Query: 881 RNIAAGAAASLPPKTASYRSWAQKLKEYASGKVLLKEAEYWKGITNTGSGPLPKDFGEEN 940 + G + PKT SY+ +A +L EYA +L+E +YW NT + +F E+ Sbjct: 4767 SQLMKGEPIAFYPKTTSYKEYATQLNEYAKSAKILREKQYW---VNTLKDNV--NFLEKK 4821 Query: 941 RGCG-ERMEVSLNFSK----EQTAKLLRNCNTAYNTQINDVLLCSLGLAFKEWGGMDQLL 995 G R E S FS E+T++LLR N AY+T+IND+L+ +L +A + G +++ Sbjct: 4822 EEVGLFRYEDSDTFSTALGIEETSRLLRETNQAYHTEINDLLISALLIATRRVTGENKIR 4881 Query: 996 VSLEGHGREEIFQGVSIDRTIGWFTTIFPVVLDMTRSHDLAYSLKRTKEMLRHVPHKGIG 1055 ++LEGHGRE+I + V I RT+GWFTT +PV +++ DL+ ++K KE LR +P+KGIG Sbjct: 4882 INLEGHGREQIIKNVDISRTVGWFTTKYPVYINLGDEKDLSMTIKTVKESLRRIPNKGIG 4941 Query: 1056 YGIWKYLADGNKELRAFE-PEVSFNYLGEFGREAGSSLLEFSRLSSGASISIDNNKLKGI 1114 YG+ K L+ G+ +L + E P + FNYLG+ + +++ S +S+G SI + + I Sbjct: 4942 YGVLKQLS-GDSDLWSIEQPPILFNYLGQMDADLNNTIFSSSWISAGESIGGKHTRETPI 5000 Query: 1115 DINGLIMEGELELVFSYSTLEYTRETVAQLTAAYHTSLLQVIDHCAHRQTAEKTPWDYGD 1174 +IN ++++G+L + +Y+T Y + V + T A+ +LL VI HC ++ AEKTP+DYGD Sbjct: 5001 EINAIVLDGKLTIDTTYNTKVYAEDVVVEFTEAFKAALLDVIHHCISKEQAEKTPFDYGD 5060 Query: 1175 PDLSLEDLDTLLACGQ--EIEKIHSLSPMQEGMMYNTIVDAGSSTYFEQSELNIEGYLNV 1232 +LS E L+ + A + EIEKI+ L+ MQ+GM+++ + D S YFEQ ++++G+++V Sbjct: 5061 KELSFEQLEEIKAKNRWGEIEKIYPLANMQQGMLFHALEDPQSGAYFEQLVIDVKGFIDV 5120 Query: 1233 EILNMVLNELTGKYEILRTAFFYHDIKKFKQAVLKERKLRIHYEDISSRSMQEQSSYIEQ 1292 + LN++ ++EILRTA Y ++ K ++K RK+ Y DI + + +Q I Sbjct: 5121 NLFEESLNDIMKRHEILRTAIEYEITEQPKNVIIKGRKIGFRYRDIRQQGIDQQKESITT 5180 Query: 1293 FKVQDRSNPFDLEQDCLLRVAVLKTDTGNFKVVYSFHHIIMDGWSAGIILQEVIAQYKAR 1352 + QDR FD +D L+R+ +++TD + +++S HHI+ DGW GIIL E+ Y + Sbjct: 5181 YIEQDREKGFDFSKDVLIRLELIQTDDKAYTIIWSNHHILFDGWGRGIILGELFHIYGNK 5240 Query: 1353 LQEAELKQEKAVPYSDYLDWLDHQDKAAALDYWQSYLEAYESGTVIPELQHQEKGFMHQQ 1412 E+ PYSDY+ WL Q+K + YW+ YL Y+ +P + H Q Sbjct: 5241 QVGQYPNLEEPRPYSDYIRWLGEQEKEEGIQYWKQYLAGYQKPAKVPSFKIDSTREYHGQ 5300 Query: 1413 ER-TSLDAQATAKLKSLAEANGITLSSVIQTAWGVVLQKYSNTHDVVFGSVVSGRPSDIK 1471 E + T K+ LA N +TL++V+QT WG++L KY++T DVVFGSVVSGR + + Sbjct: 5301 ETLIEFSRELTKKMTELANQNNVTLNTVLQTLWGIILAKYNHTDDVVFGSVVSGRDAKVA 5360 Query: 1472 GIERMVGLCINTVPVRVTGGDQLSFIALAKKLNKDFIHANAFSFCQLAEIQALSPMKNNL 1531 GIE+MVGL IN +P R+ +Q SF + K++ + I + A+++ L++IQ+LS +K +L Sbjct: 5361 GIEKMVGLFINAIPTRINIKEQKSFKNILKEVQQQAIESQAYNYMNLSDIQSLSDLKRDL 5420 Query: 1532 INHVVVYENYPVDQSLADLQEAEGREVKI-TAAQGFEQTNYDLEILIAPGRTLQIKITYN 1590 I+HV+++ENY +D+ L LQE E + + +G EQTNY I++ PG L +KI+Y+ Sbjct: 5421 IDHVMIFENYALDERL--LQEEESKSSFVFKDIKGIEQTNYGFTIVVVPGEQLVLKISYD 5478 Query: 1591 GCKYSRDVINALMDNLMHVLSCAVSNPDQAAESIDMVSEQERNKLLYELNCTGTAYAKEK 1650 G YS +I + ++L +++ V + ++ ++++S++E++ L E N T Y KEK Sbjct: 5479 GNLYSEKLIQNIANHLKNIMDEVVQDENKNVNQLEILSKEEKHYFLNEFNETKAEYPKEK 5538 Query: 1651 TIAQLFEEQAERTPEAIALEFHGTVLSYRELNKRANQLARVLRRNSVGANVIVPILVKRS 1710 TI +LFEEQ ERTP +A+ F L+Y+ELN+++NQ+AR+L+ V + +V I+++RS Sbjct: 5539 TIHRLFEEQVERTPNKVAVVFDKQQLTYKELNEKSNQIARLLQNKGVQPDTVVGIMLERS 5598 Query: 1711 LNLLVGILGILKAGGGYLPLDTDYPVDRIHYMLQDSQASLLLTEKGLAAPLGLNEAVTIL 1770 L +++GI+GILK+G YLP+D +YP +RI Y+++DS +++LT KG A + L++ + L Sbjct: 5599 LEMIIGIMGILKSGAAYLPIDPEYPEERIKYIVEDSGTNIILT-KGKDA-VRLSKEIVFL 5656 Query: 1771 DIGSKQIQDEDDSNLQSITKADDLAYVLYTSGSTGNPKGVAVEQRGVHNFIKGITDRISF 1830 D ++ N++ + ++LAY++YTSGSTG PKG ++QRG+ N+I Sbjct: 5657 D---EEYNHYSTENIKVTSNTNNLAYMIYTSGSTGMPKGTMLKQRGLVNYITWANKEYVK 5713 Query: 1831 TEDKIILSVTTCSFDIFGLESLLPLTRGLKVVIASEEEQKDPHLLNKVILDSEVNTIQLT 1890 E ++ SFD+ PL G K+VI + + D ++ K+ D+ V ++LT Sbjct: 5714 GEALDFALYSSFSFDLTITSLFTPLISGNKIVIYNND--GDEPIIRKIFKDNRVGIVKLT 5771 Query: 1891 PSRLKLMLNCSNTAESFKKLKLMMIGGEGFPKDLLVQ-LQKFT-DSRIYNMYGPTETTIW 1948 PS L+L+ + N+ S K+L ++GGE +L + L+ F + IYN YGPTETTI Sbjct: 5772 PSHLRLIRDIDNSNSSIKRL---IVGGEDLKTELAREILKSFNHNVEIYNEYGPTETTIG 5828 Query: 1949 STVKELTHEN----SVNVGKPIANTQVYIVDQAGHLAPIGVAGELCIAGDGVARGYLHKE 2004 + + + + SV +GKPI N Q+YI+D + P+G+ GEL I+GDGVA GYL++ Sbjct: 5829 CMIYKYSLNDDKHISVPIGKPIDNVQIYILDDNQKILPVGIEGELYISGDGVATGYLNRP 5888 Query: 2005 ELTASKFVDNPFMQGTKMYTTGDLARWLPNGELDVIGRLDNQVKIGGYRIELGEIESVAA 2064 ELTA KF+ NP++ G KMY TGDLARWLP+G ++ IGR D+QVKI GYRIELGEIE+ Sbjct: 5889 ELTAEKFISNPYVPGAKMYRTGDLARWLPSGNIEFIGRTDHQVKIRGYRIELGEIENQIL 5948 Query: 2065 RHDKITQCVVAGQPNSLGSQDLVLYFVAAEK---ISTSELVNFLSPVLPKYMMPQMYIQI 2121 + D I + V + + SQ L Y V K I+ +E+ +LS LP YM+P + Q+ Sbjct: 5949 KLDNIKETKVVARIDGEDSQYLCAYVVLENKEKAITVTEMRRYLSKELPNYMIPAFFTQL 6008 Query: 2122 DEIPLTANGKTNLKALPKP-GNVRPELRDDYEEAVTDLQKEIQQVWSLILNIEQVGIYDN 2180 E+PLT NGK ++ +LP P GNV+ L +YE DL+++I +W ILNI+++G+ N Sbjct: 6009 KELPLTTNGKIDINSLPAPDGNVQYGL--EYEPPRNDLEEKIVSIWEEILNIKKIGMNTN 6066 Query: 2181 FFEVGGNSLKIVAMYNELQKLYPGKIQITDIFSYPTISRLAQFID 2225 F++G NSL ++ + + ++ D+F PT+ + F++ Sbjct: 6067 LFDIGANSLNVMTFVSRIVAELNFRVPFKDVFDKPTVRSFSAFLE 6111 Score = 768 bits (1984), Expect = 0.0, Method: Compositional matrix adjust. Identities = 392/1043 (37%), Positives = 641/1043 (61%), Gaps = 17/1043 (1%) Query: 1201 MQEGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEILRTAFFYHDIKK 1260 MQ+G++++ I D S YFEQ L+I+GY++ I NE+ ++E+LR +F Y + + Sbjct: 1 MQKGILFHAIEDKNSDAYFEQIILDIKGYVDETIFEESFNEIMKRHEVLRASFNYK-LDE 59 Query: 1261 FKQAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDRSNPFDLEQDCLLRVAVLKTDTG 1320 +L++RK++ Y D+S+ + + Y+E++ V D+ FDL ++ L+R+ ++KT+ Sbjct: 60 PLHVILRDRKIKFSYNDVSNLDLNTKDLYVEKYIVDDKVKGFDLTKETLMRICLIKTNDN 119 Query: 1321 NFKVVYSFHHIIMDGWSAGIILQEVIAQYKARLQEAELKQEKAVPYSDYLDWLDHQDKAA 1380 ++KV++SFHHI++DGW GIIL E+ Y +++ E + E PYSDY++WL++QD Sbjct: 120 SYKVIWSFHHILLDGWCIGIILDELFTIYSHKMKGEEHQLEDPRPYSDYINWLNNQDNEE 179 Query: 1381 ALDYWQSYLEAYESGTVIPELQHQEKGFMHQQERT-SLDAQATAKLKSLAEANGITLSSV 1439 L YW YLE YE +P+ + G ++E+ + T K+ LA N +TL++V Sbjct: 180 GLKYWSKYLEGYELTATLPKFNNSSAGKYQRREKVIEFSKELTDKITQLANKNNVTLNTV 239 Query: 1440 IQTAWGVVLQKYSNTHDVVFGSVVSGRPSDIKGIERMVGLCINTVPVRVTGGDQLSFIAL 1499 +Q+ WG++L KY+N+ DVVFG+VVSGR + ++GIE M+GL INT+P R+ + SF + Sbjct: 240 MQSIWGLILAKYNNSEDVVFGTVVSGRDAAVEGIENMLGLFINTIPTRIKLQSEKSFKEV 299 Query: 1500 AKKLNKDFIHANAFSFCQLAEIQALSPMKNNLINHVVVYENYPVDQSLADLQEAEGREVK 1559 K D I N +++ LAE+QALS +K+NLI+H++V+ENY +D+ + +E+ G + Sbjct: 300 LKATQHDAIEGNDYNYINLAEVQALSNLKSNLIDHILVFENYAIDEKGLEEKES-GLGFE 358 Query: 1560 ITAAQGFEQTNYDLEILIAPGRTLQIKITYNGCKYSRDVINALMDNLMHVLSCAVSNPDQ 1619 + + E++NY L + + G L++ I Y+ Y +IN L ++ +V + N + Sbjct: 359 VVSVTDEERSNYSLSLTVGIGEKLKLTIVYDENVYEERLINNLECHIQNVTKQVIENDAK 418 Query: 1620 AAESIDMVSEQERNKLLYELNCTGTAYAKEKTIAQLFEEQAERTPEAIALEFHGTVLSYR 1679 ID++SE+ERN LLY+ N T Y K++ I QLFEEQ E+TP+ +A+ F L+YR Sbjct: 419 KLIDIDLISEEERNILLYKFNETTVEYPKDRLIHQLFEEQVEKTPDRVAVSFKSNNLTYR 478 Query: 1680 ELNKRANQLARVLRRNSVGANVIVPILVKRSLNLLVGILGILKAGGGYLPLDTDYPVDRI 1739 ELN+++NQ+AR+LR V +N IV I+V RSL +++GI+GILK+G YLP+D + P +RI Sbjct: 479 ELNEKSNQIARLLREKGVQSNTIVGIMVDRSLEMIIGIMGILKSGAAYLPIDPETPKERI 538 Query: 1740 HYMLQDSQASLLLTEKGLAAPLGLNEAVTILDIGSKQIQDEDDSNLQSITKADDLAYVLY 1799 YMLQDS +LLT+ + L LN V ++++ + NL I + D AY++Y Sbjct: 539 DYMLQDSNVKVLLTQDRCISQLNLN--VELINLDQENFLRLSTDNLNLINHSSDTAYIIY 596 Query: 1800 TSGSTGNPKGVAVEQRGVHNFIKGITDRISFTEDKIILSVTTCSFDIFGLESLLPLTRGL 1859 TSGSTG PKGV + +K T+ I E+ IL ++ +FD + L G Sbjct: 597 TSGSTGTPKGVVIPHYSAIRVVKN-TNYIEINENDTILQLSNYAFDGSIFDIYGALLNGA 655 Query: 1860 KVVIASEEEQKDPHLLNKVILDSEVNTIQLTPSRLKLMLNCSNTAESFKKLKLMMIGGEG 1919 K+++ ++ L K+I + +++ + +T + +++ + K++ ++ GGE Sbjct: 656 KLIMVEKDTVLSLVKLAKLIKEEQISIMFITTALFNALVDLE--IDCLDKIRKILFGGER 713 Query: 1920 FPKDLLVQ-LQKFTDSRIYNMYGPTETTIWST---VKELTHENSVNVGKPIANTQVYIVD 1975 + + L+K +I ++YGPTE+T+++T V E+T + +GKP+ANT V++VD Sbjct: 714 VSVSHVNKALEKLGKDKIIHVYGPTESTVYATYYFVNEVTE--VIPIGKPLANTSVFVVD 771 Query: 1976 QAGHLAPIGVAGELCIAGDGVARGYLHKEELTASKFVDNPFMQGTKMYTTGDLARWLPNG 2035 + +L P+GV GELCI+GDG+++GYL+ E LT +FV NPF+ G +MY TGDL R LP+G Sbjct: 772 KNSNLLPLGVPGELCISGDGLSKGYLNNERLTVQRFVPNPFILGERMYRTGDLVRMLPDG 831 Query: 2036 ELDVIGRLDNQVKIGGYRIELGEIESVAARHDKITQCVVAGQPNSLGSQDLVLYFVAAE- 2094 ++ +GR+D+QVKI G+RIELGEIES +H ++ + VV + ++ Q L YF + Sbjct: 832 NIEFLGRIDHQVKIRGFRIELGEIESQLLKHKEVKEAVVIAREDNSHHQYLCAYFTSESS 891 Query: 2095 --KISTSELVNFLSPVLPKYMMPQMYIQIDEIPLTANGKTNLKALPKPGNVRPELRDDYE 2152 +I E+ FL+ LP+YM+P ++Q+D++PLT NGK + KALP P +YE Sbjct: 892 KGEIRVQEIRKFLAKELPEYMIPAFFVQLDKLPLTTNGKVDRKALPSPDESSVAGVVEYE 951 Query: 2153 EAVTDLQKEIQQVWSLILNIEQVGIYDNFFEVGGNSLKIVAMYNELQKLYPGKIQITDIF 2212 +++++ +W IL+IE +GI NFFE+GG+SLK M + + K ++ + IF Sbjct: 952 APRNTVEEKLVSIWQDILDIENIGIQHNFFEIGGHSLKATTMVSRIHKELMVELPLRQIF 1011 Query: 2213 SYPTISRLAQFIDNQSAFAEAAV 2235 PTI + ++ID+ A++ Sbjct: 1012 QTPTIKGIGEYIDSTKESVYASI 1034 Score = 550 bits (1417), Expect = e-154, Method: Compositional matrix adjust. Identities = 334/913 (36%), Positives = 517/913 (56%), Gaps = 38/913 (4%) Query: 26 RNPLFDVMFVLEN--LDYGLGPNEEQAKVKLIEPM--AEVAKFDLTLTAKEAGGNLDFSL 81 +N L D + V EN +D + NE+ +E + E + + ++ A G L+ L Sbjct: 2868 KNDLIDHIIVFENYAVDKRIAGNEKMDIGFEVEDIHAEEQSNYSFSIAAT-PGEQLNLVL 2926 Query: 82 EYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGGLDMLSNQEKHLLLNVFKGTPTDYP 141 Y +++ + + H ++ + A+ +K++ +D+++ +E+ LL F T DYP Sbjct: 2927 TYDGNIYDDKIIDNIEMHIKKVTEQVIADENKKINEIDIIAEEERTTLLYEFNDTKVDYP 2986 Query: 142 KDKTIHELFEEQADRTPDQLAVVCGGQALTYSELNEQANSLASVLREKGVGAEAIVGIMA 201 K+KTIH+LF+EQ +RTP+ +AVV + LTY ELNE++N +A++LREKGV + +VGIM Sbjct: 2987 KEKTIHQLFQEQVERTPENIAVVFENKQLTYWELNEKSNQVAALLREKGVKSNTVVGIMV 3046 Query: 202 DRSLELIIAILGTLKAGGAYLPIDPEYPADRINYMLTDSQAAMLLFQHHIVKDLTYAGGR 261 +RS+E+I+ ++ LKAGGAYLPIDPEYP DR YML DS +LL Q + K + Y Sbjct: 3047 ERSIEMIVGMMAILKAGGAYLPIDPEYPEDRRRYMLEDSGIEILLKQEN--KQVDYDLTC 3104 Query: 262 LELENSELYIRETGNPVKASLPENLAYVIYTSGTTGTPKGVMVEHRNLVNYIHWANKRYV 321 +++ ++ R T N + ++AY+IYTSG+TG PKGVMV H++++N + W + Y Sbjct: 3105 IDINVQKIKDRFTENLPSLNKSADMAYIIYTSGSTGKPKGVMVNHKSILNTLCWRIESYQ 3164 Query: 322 AGEQTAFPLYSSISFDLTVTSIYTPLISGNT-IVIYDGEDKALLTRTIAEENKV-NIVKL 379 + S SFD +V I+T L+SG I+I D I + NKV N++ + Sbjct: 3165 YSDSDITLQMPSFSFDSSVEDIFTTLLSGGKLILIEDIRMNFSKFINIIQNNKVTNLLAV 3224 Query: 380 TPTHLRLLEDMDLSRSSIRTFIVGGEDLKIKVAEKIHRAFDGRIEIYNEYGPTEATVGCM 439 + LL +D +R + GE + K H ++++NEYGPTE +V Sbjct: 3225 PSYYNNLLNTIDKPLLDLRFVTIAGEGFNENLITK-HFQKIPHVKLFNEYGPTENSVCST 3283 Query: 440 IYKYNAERDKGTSVSIGIPADNTQLYIVGSRMELLPVGVAGELCIGGDGVARGYLHKEAL 499 I + E K V IG P N ++YI+ L+P+GVAGELC+ G+G+ARGYL++ L Sbjct: 3284 ICELKQEDQK---VLIGKPISNNRVYILDMENNLVPLGVAGELCVSGEGLARGYLNRPEL 3340 Query: 500 TAEKFVDHPFNAGSKLYKTGDMARWLSDGTVEYLGRMDNQVKIRGYRIETGEIENRLLQM 559 TAEKFV +PF G ++Y+TGD+AR L +G +E+LGR+D+QVKIRG+RIE GE+EN+L + Sbjct: 3341 TAEKFVPNPFIPGERMYRTGDLARLLPNGNIEFLGRIDHQVKIRGFRIELGEVENQLFKQ 3400 Query: 560 PDITEAVVVARTDEQGHNYLCAYVVS---NKEVIASEVKGRLSKELPNYMVPGFTVQIAK 616 +I EAVV+AR D G YLCAY S KE E++ L++ELP YM+P F VQ+ K Sbjct: 3401 KEIKEAVVIAREDNNGQPYLCAYFTSETRKKESKLQEIRKDLAQELPEYMIPAFFVQLDK 3460 Query: 617 LPLSSNGKVDIKALPAVDISEMLAASYEAPNNKVEEILVDVWQRVLNIEPIGTNYNYYEM 676 LPL++NGKVD KALP D S ++ YEAP N+VEE LV +WQ +L +E IG N +++E+ Sbjct: 3461 LPLTANGKVDRKALPEPDESAVVGVEYEAPRNEVEERLVSIWQEILGVEKIGINQHFFEI 3520 Query: 677 GGDSIKSILIVSAL-REHGLRLEVKDLMQYPSIKELAGYV--KHEDVQAPQEAVEGS--V 731 GG S+K+ +VS + +E + + ++ + Q P+IK + ++ E V A + VE Sbjct: 3521 GGHSLKATTMVSKIHKELMVEIPLRQIFQTPTIKGIGEFIDSTKESVYASIKKVEEQDYY 3580 Query: 732 PFLPVQQWFFEQGLPQEN--HYNQAFMFYRKEGLDEEILRKAVVAILVHHDALRMVYKRT 789 P Q+ + + N YN F K LD + L KA ++ H+ALR + Sbjct: 3581 PLSSAQKRLYILNKIEGNGVSYNIPFAMKIKGDLDVQQLEKAFHKLIERHEALRTSFVMV 3640 Query: 790 PDGITQWNRSADCAGAAFTLDVYDLRGQDEKRSIPALSDELQKGLDLEEGLLVKLGLFKT 849 DG D Y G ++ + + + K DLE+ L+++ + Sbjct: 3641 -DGEPVQKIEKDIDFQV----TYREMGTNK---LDDIINGFVKPFDLEKAPLLRVEIIHV 3692 Query: 850 SLGDHLLVA-VHHLVIDGVSWRILIADLETAYRNIAAGAAASLPPKTASYRSWAQKLKEY 908 + +H++V +HH++ DGVS I +L Y L P + Y+ ++ +E Sbjct: 3693 TDDEHVIVLDMHHIISDGVSMGIFTQELAELYN------GKELSPLSIQYKDYSVWQREL 3746 Query: 909 ASGKVLLKEAEYW 921 + + + K+ EYW Sbjct: 3747 FTQEEMKKQEEYW 3759 Score = 531 bits (1369), Expect = e-148, Method: Compositional matrix adjust. Identities = 350/1014 (34%), Positives = 540/1014 (53%), Gaps = 63/1014 (6%) Query: 19 NLKSDASRNPLFDVMFVLENL---DYGLGPNEEQAKVKLIEPM-AEVAKFDLTLTAKEAG 74 NLKS+ L D + V EN + GL E +++ E + + L+LT G Sbjct: 326 NLKSN-----LIDHILVFENYAIDEKGLEEKESGLGFEVVSVTDEERSNYSLSLTVG-IG 379 Query: 75 GNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGGLDMLSNQEKHLLLNVFK 134 L ++ Y ++ + + + H + + N K+L +D++S +E+++LL F Sbjct: 380 EKLKLTIVYDENVYEERLINNLECHIQNVTKQVIENDAKKLIDIDLISEEERNILLYKFN 439 Query: 135 GTPTDYPKDKTIHELFEEQADRTPDQLAVVCGGQALTYSELNEQANSLASVLREKGVGAE 194 T +YPKD+ IH+LFEEQ ++TPD++AV LTY ELNE++N +A +LREKGV + Sbjct: 440 ETTVEYPKDRLIHQLFEEQVEKTPDRVAVSFKSNNLTYRELNEKSNQIARLLREKGVQSN 499 Query: 195 AIVGIMADRSLELIIAILGTLKAGGAYLPIDPEYPADRINYMLTDSQAAMLLFQHHIVKD 254 IVGIM DRSLE+II I+G LK+G AYLPIDPE P +RI+YML DS +LL Q + Sbjct: 500 TIVGIMVDRSLEMIIGIMGILKSGAAYLPIDPETPKERIDYMLQDSNVKVLLTQDRCISQ 559 Query: 255 LTYAGGRLELENSELYIRETGNPVKASLPENLAYVIYTSGTTGTPKGVMVEHRNLVNYIH 314 L + L+ T N + + AY+IYTSG+TGTPKGV++ H + + + Sbjct: 560 LNLNVELINLDQENFLRLSTDNLNLINHSSDTAYIIYTSGSTGTPKGVVIPHYSAIRVVK 619 Query: 315 WANKRYVAGEQTAFPLYSSISFDLTVTSIYTPLISGNTIVIYDGEDKALLTR--TIAEEN 372 N + T L S+ +FD ++ IY L++G +++ + + L + + +E Sbjct: 620 NTNYIEINENDTILQL-SNYAFDGSIFDIYGALLNGAKLIMVEKDTVLSLVKLAKLIKEE 678 Query: 373 KVNIVKLTPTHLRLLEDMDL-SRSSIRTFIVGGEDLKIKVAEKIHRAFD--GRIEIYNEY 429 +++I+ +T L D+++ IR + GGE + + +++A + G+ +I + Y Sbjct: 679 QISIMFITTALFNALVDLEIDCLDKIRKILFGGERVSVS---HVNKALEKLGKDKIIHVY 735 Query: 430 GPTEATVGCMIYKYNAERDKGTSVSIGIPADNTQLYIVGSRMELLPVGVAGELCIGGDGV 489 GPTE+TV Y N + + IG P NT +++V LLP+GV GELCI GDG+ Sbjct: 736 GPTESTVYATYYFVN---EVTEVIPIGKPLANTSVFVVDKNSNLLPLGVPGELCISGDGL 792 Query: 490 ARGYLHKEALTAEKFVDHPFNAGSKLYKTGDMARWLSDGTVEYLGRMDNQVKIRGYRIET 549 ++GYL+ E LT ++FV +PF G ++Y+TGD+ R L DG +E+LGR+D+QVKIRG+RIE Sbjct: 793 SKGYLNNERLTVQRFVPNPFILGERMYRTGDLVRMLPDGNIEFLGRIDHQVKIRGFRIEL 852 Query: 550 GEIENRLLQMPDITEAVVVARTDEQGHNYLCAYVVSNK---EVIASEVKGRLSKELPNYM 606 GEIE++LL+ ++ EAVV+AR D H YLCAY S E+ E++ L+KELP YM Sbjct: 853 GEIESQLLKHKEVKEAVVIAREDNSHHQYLCAYFTSESSKGEIRVQEIRKFLAKELPEYM 912 Query: 607 VPGFTVQIAKLPLSSNGKVDIKALPAVDISEMLA-ASYEAPNNKVEEILVDVWQRVLNIE 665 +P F VQ+ KLPL++NGKVD KALP+ D S + YEAP N VEE LV +WQ +L+IE Sbjct: 913 IPAFFVQLDKLPLTTNGKVDRKALPSPDESSVAGVVEYEAPRNTVEEKLVSIWQDILDIE 972 Query: 666 PIGTNYNYYEMGGDSIKSILIVSAL-REHGLRLEVKDLMQYPSIKELAGYV--KHEDVQA 722 IG +N++E+GG S+K+ +VS + +E + L ++ + Q P+IK + Y+ E V A Sbjct: 973 NIGIQHNFFEIGGHSLKATTMVSRIHKELMVELPLRQIFQTPTIKGIGEYIDSTKESVYA 1032 Query: 723 PQEAVEGS--VPFLPVQQWFFEQGLPQEN--HYNQAFMFYRKEGLDEEILRKAVVAILVH 778 + VE P Q+ + + + YN F K LD L ++ Sbjct: 1033 SIKKVEEQDYYPLSSAQRRLYILNKIEGSGVSYNMPFAMKIKGDLDVHQLENTFYKLIER 1092 Query: 779 HDALRMVYKRTPDG--ITQWNRSADCAGAAFTLDVYDLRGQDEKRSIPALSDELQKGLDL 836 H+ALR + DG + + + D Y G ++ + + + K DL Sbjct: 1093 HEALRTSFVMV-DGEPVQKIEKEIDFQVT------YREMGTNK---LDEMINGFVKPFDL 1142 Query: 837 EEGLLVKLGLFKTSLGDHLLVA-VHHLVIDGVSWRILIADLETAYRNIAAGAAASLPPKT 895 E+G L+++ + + +H++V +HH++ DGVS IL +L Y L P Sbjct: 1143 EKGPLLRVEIIHVTDDEHVMVLDMHHIISDGVSMNILNRELCKLYE------GKELSPLD 1196 Query: 896 ASYRSWAQKLKEYASGKVLLKEAEYWKGITNTGSGPL--PKDFGEENRGCGERMEVSLNF 953 Y+ +A K+ + + + K+ EYW + L P D+ E S Sbjct: 1197 LQYKDYAVWQKDLFTQEEMKKQEEYWINVFKEEVPILNMPTDYKRPPTQSVEGARRSFEI 1256 Query: 954 SKEQTAKLLR----NCNTAYNTQINDVLLCSLGLAFKEWGGMDQLLVSLEGHGR 1003 E T L R N T Y +LL + G D ++V GR Sbjct: 1257 DSELTKNLNRIAKENGVTMYM-----LLLAGYTTLLSRYTGQDDIVVGSPIAGR 1305 Score = 526 bits (1354), Expect = e-146, Method: Compositional matrix adjust. Identities = 334/1050 (31%), Positives = 570/1050 (54%), Gaps = 54/1050 (5%) Query: 1196 HSLSPMQEGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEILRTAFFY 1255 + LS Q + ++ +Y + I+G L+V L +L ++E LRT+F Sbjct: 1043 YPLSSAQRRLYILNKIEGSGVSYNMPFAMKIKGDLDVHQLENTFYKLIERHEALRTSFVM 1102 Query: 1256 HDIKKFKQAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDRSNPFDLEQDCLLRVAVL 1315 D + Q + KE ++ Y ++ + + E + PFDLE+ LLRV ++ Sbjct: 1103 VDGEPV-QKIEKEIDFQVTYREMGTNKLDEM--------INGFVKPFDLEKGPLLRVEII 1153 Query: 1316 KTDTGNFKVVYSFHHIIMDGWSAGIILQEVIAQYKAR-LQEAELKQEKAVPYSDYLDW-- 1372 +V HHII DG S I+ +E+ Y+ + L +L+ Y DY W Sbjct: 1154 HVTDDEHVMVLDMHHIISDGVSMNILNRELCKLYEGKELSPLDLQ------YKDYAVWQK 1207 Query: 1373 --LDHQDKAAALDYWQSYLEAYESGTVIPELQHQEKGFMHQQERTS--LDAQATAKLKSL 1428 ++ +YW + + +P + + R S +D++ T L + Sbjct: 1208 DLFTQEEMKKQEEYWINVFKEEVPILNMPTDYKRPPTQSVEGARRSFEIDSELTKNLNRI 1267 Query: 1429 AEANGITLSSVIQTAWGVVLQKYSNTHDVVFGSVVSGRPSDIKGIERMVGLCINTVPVRV 1488 A+ NG+T+ ++ + +L +Y+ D+V GS ++GR E +VG+ +NT+ +R Sbjct: 1268 AKENGVTMYMLLLAGYTTLLSRYTGQDDIVVGSPIAGRSH--HDFENIVGMFVNTLAMRN 1325 Query: 1489 TGGDQLSFIALAKKLNKDFIHANAFSFCQLAEIQALSPMKNNLINHVVVYENYPVDQSLA 1548 + +F +++ ++ + A L E+ ++ ++ + +++ V Q+L Sbjct: 1326 YPNEDKTFRNYLREVKENALKAYENQDYPLDELVEKLDLQRDM-SRSALFDTMFVLQNL- 1383 Query: 1549 DLQEAEGREVKITAAQGFEQ----TNYDLEI-LIAPGRTLQIKITYNGCKYSRDVINALM 1603 + E+K + + ++ N+DL + + ++ + Y + ++ I + Sbjct: 1384 ---DTSNEEIKGLSFETYDSELNIANFDLTLSAVETNNIIKFDLEYCTKLFKKETIAKIS 1440 Query: 1604 DNLMHVLSCAVSNPDQAAESIDMVSEQERNKLLYELNCTGTAYAKEKTIAQLFEEQAERT 1663 ++ + +L +N + IDM+S +E++ LL E N T Y K KTI QLFEEQ ERT Sbjct: 1441 EHFVSILREITNNQEVCLGQIDMLSGEEKHILLNEFNETYMDYPKNKTIYQLFEEQVERT 1500 Query: 1664 PEAIALEFHGTVLSYRELNKRANQLARVLRRNSVGANVIVPILVKRSLNLLVGILGILKA 1723 P +A+EF G ++Y+ELN+++NQ+ARVL V +IV I+V+RSL+++VGI+GILK+ Sbjct: 1501 PNKVAVEFEGQQVTYKELNEKSNQVARVLYDKGVHPEMIVGIMVERSLDMIVGIMGILKS 1560 Query: 1724 GGGYLPLDTDYPVDRIHYMLQDSQASLLLTEKGLAAPLGL--NEAVTILDIGSKQIQDED 1781 G YLP+D +YP +RI YM++DS A +LT+ L L NE +T + I + I++++ Sbjct: 1561 GAAYLPIDPEYPEERIKYMVEDSNAKFVLTQTHLYDKLHFINNECITKISINDETIKNQE 1620 Query: 1782 DSNLQSITKADDLAYVLYTSGSTGNPKGVAVEQRGVHNFIKGITDRISFTEDKIILSVTT 1841 N++ +DLAYV+YTSGSTG PKGV VE + N D TE I + Sbjct: 1621 QINMERRNNRNDLAYVIYTSGSTGLPKGVLVEHHSLVNLCNWYVDFHKITERDRITNYLK 1680 Query: 1842 CSFDIFGLESLLPLTRGLKVVIASEEEQKDPHLLNKVILDSEVNTIQLTPSRL--KLMLN 1899 SFD E L G + + ++ + D LN+ + ++ T+ PS++ + +L Sbjct: 1681 VSFDASIGEIFPCLITGATLHVLGKDMRLDLDKLNEYMNSKDI-TVATFPSKVSEQFILQ 1739 Query: 1900 CSNTAESFKKLKLMMIGGEGFPKDLLVQLQKFTDSRIYNMYGPTETTIWSTVKELT-HEN 1958 +++ L++++ GGE L K T ++ N YGPTE T+ +T + +++ Sbjct: 1740 DNHS------LRMLVSGGEKLI------LNKNTRYQLVNAYGPTENTVVTTSFLMNKNDD 1787 Query: 1959 SVNVGKPIANTQVYIVDQAGHLAPIGVAGELCIAGDGVARGYLHKEELTASKFVDNPFMQ 2018 ++ +GKP+ NT+VYIV++ L PIGV GELCI+G G+ARGYL+ LTA KFV NPF+ Sbjct: 1788 NIPIGKPVYNTKVYIVNKYNQLCPIGVTGELCISGVGLARGYLNNPALTAEKFVGNPFVS 1847 Query: 2019 GTKMYTTGDLARWLPNGELDVIGRLDNQVKIGGYRIELGEIESVAARHDKITQCVVAGQP 2078 G KMY TGDL RW+P+G ++ IGR+D+QVKI GYRIELGEIES +H I + VV + Sbjct: 1848 GEKMYRTGDLVRWMPDGNVEFIGRIDHQVKIRGYRIELGEIESQLLKHQDIKEVVVVAKE 1907 Query: 2079 NSLGSQDLVLYFVAAEKISTSELVNFLSPVLPKYMMPQMYIQIDEIPLTANGKTNLKALP 2138 + + Y V+ + IS++++ FL LP YM+P ++Q+D++PLT+N K + KALP Sbjct: 1908 DKKNHTYISAYIVSEKAISSAKIREFLEKELPDYMIPSYFVQLDQLPLTSNDKVDRKALP 1967 Query: 2139 KPGNVRPELRDDYEEAVTDLQKEIQQVWSLILNIEQVGIYDNFFEVGGNSLKIVAMYNEL 2198 +P + + +YE +++ + ++W IL IE +GI +FF GG+S+K + + + L Sbjct: 1968 EP-DRSSQSGVEYEAPRNEVETHLVEIWRDILGIEDIGINHHFFVSGGDSIKALQIVSRL 2026 Query: 2199 QKLYPGKIQITDIFSYPTISRLAQFIDNQS 2228 ++ K+++ D+F+ P I L++++ Q+ Sbjct: 2027 SRI-NLKLEVKDLFANPKIKDLSKYVKKQN 2055 Score = 489 bits (1259), Expect = e-135, Method: Compositional matrix adjust. Identities = 328/1059 (30%), Positives = 562/1059 (53%), Gaps = 65/1059 (6%) Query: 1196 HSLSPMQEGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEILRTAFFY 1255 + LS Q+ + ++ +Y + I+G L+V+ L ++L ++E LRT+F Sbjct: 3580 YPLSSAQKRLYILNKIEGNGVSYNIPFAMKIKGDLDVQQLEKAFHKLIERHEALRTSFVM 3639 Query: 1256 HDIKKFKQAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDRSNPFDLEQDCLLRVAVL 1315 D + Q + K+ ++ Y ++ + + + I F PFDLE+ LLRV ++ Sbjct: 3640 VDGEPV-QKIEKDIDFQVTYREMGTNKLDD---IINGF-----VKPFDLEKAPLLRVEII 3690 Query: 1316 KTDTGNFKVVYSFHHIIMDGWSAGIILQEVIAQYKARLQEAELKQEKAVPYSDYLDW--- 1372 +V HHII DG S GI QE+ Y + EL ++ Y DY W Sbjct: 3691 HVTDDEHVIVLDMHHIISDGVSMGIFTQELAELYNGK----EL-SPLSIQYKDYSVWQRE 3745 Query: 1373 -LDHQDKAAALDYWQSYLEAYESGTVI--------PELQHQEKGFMHQQERTSLDAQATA 1423 ++ +YW + E V+ P +Q E +H + +D+ Sbjct: 3746 LFTQEEMKKQEEYWMHVFK--EEVPVLNMPTDYKRPPIQSTEGDLVHFE----IDSDIYV 3799 Query: 1424 KLKSLAEANGITLSSVIQTAWGVVLQKYSNTHDVVFGSVVSGRPSDIKGIERMVGLCINT 1483 LK +A+ +G+TL ++ + +L KY+ ++V GS ++GRP D +++++G+ +NT Sbjct: 3800 NLKKMAKEHGVTLYMLLLAGYTTLLSKYTGQEEIVVGSPIAGRPHD--DLKQIMGIFVNT 3857 Query: 1484 VPVRVTGGDQLSFIALAKKLNKDFIHA---NAFSFCQLAEIQALSP--MKNNLINHVVVY 1538 + +R +SF K++ + + A + F +L E L ++ L + ++V Sbjct: 3858 LAMRNYPKRDVSFQDYLKEVKDNALKAYENQDYPFDELVEKLDLKRDMSRSALFDTMLVL 3917 Query: 1539 ENYPVDQSLADLQEAEGREVKITAAQGFEQTNYDLEIL-IAPGRTLQIKITYNGCKYSRD 1597 +N+ D ++Q ++ A + +DL + + R+++ + Y + ++ Sbjct: 3918 QNFDYDD--FEIQGLTFSPYQMKA----HVSKFDLTLTAVEEERSIKCVLNYRTKLFKKE 3971 Query: 1598 VINALMDNLMHVLSCAVSNPDQAAESIDMVSEQERNKLLYELNCTGTAYAKEKTIAQLFE 1657 + L +L+ V + P+Q+ + I ++SE+E LL + T Y K+KTI+QLFE Sbjct: 3972 TVERLAKHLIQVFKEIIEKPEQSIQDIMLLSEEEVQMLLQDDKDTKADYPKDKTISQLFE 4031 Query: 1658 EQAERTPEAIALEFHGTVLSYRELNKRANQLARVLRRNSVGANVIVPILVKRSLNLLVGI 1717 EQ +RTP +A+ F L+Y ELN+RANQ+AR+L+ + V +LV+ SL +++GI Sbjct: 4032 EQVKRTPHHVAVVFKNQKLTYLELNERANQMARLLQEKGAKPGITVGMLVEESLEMIIGI 4091 Query: 1718 LGILKAGGGYLPLDTDYPVDRIHYMLQDSQASLLLTEKGLAAPLGLNEAVTILDIGSKQI 1777 + +LKAG YLP+D + R + +L+DS ASLL+ + L N V ++ S I Sbjct: 4092 MAVLKAGATYLPIDPEQLDKRTNVILKDSNASLLIVKGERKETLQFNAEVISMEDDS--I 4149 Query: 1778 QDEDDSNLQSITKADDLAYVLYTSGSTGNPKGVAVEQRGVHNFIKGITDRISFTEDKIIL 1837 ++ D SNL K + AY++YTSGSTG PKGV V+ V N++ T + E + Sbjct: 4150 KERDTSNLLVNYKWNHNAYIIYTSGSTGTPKGVCVQHNNVVNYMTWFTKEANLKETDKAM 4209 Query: 1838 SVTTCSFDIFGLESLL-PLTRGLKVVIASEEEQKDPHLLNKVILDSEVNTIQLTPSRLKL 1896 V++ +FD+ G SL L G ++ + ++E + + I + ++ ++LTPS + Sbjct: 4210 LVSSYAFDL-GYTSLYSSLLNGCELHLVTKEVYTNAQKALQYIEEQGISYLKLTPSLFNV 4268 Query: 1897 MLN--CSNTAESFKKLKLMMIGGEGF-PKDLLVQLQKFTDSRIYNMYGPTETTIWSTVKE 1953 ++N + +S K L+L+++GGE P D+ + + + N YGPTE TI S + Sbjct: 4269 LVNDPSFSNNQSCKTLRLVVLGGEKINPIDVETFYTHYPNHAVMNHYGPTEATIGSVYQV 4328 Query: 1954 LTHENSVN------VGKPIANTQVYIVDQAGHLAPIGVAGELCIAGDGVARGYLHKEELT 2007 + ++ +G+PI N + Y+VDQ L P GV GELC++GDGVA GYL++ +LT Sbjct: 4329 IEYDTMAAFKECPVIGRPIQNMKAYVVDQQMKLVPEGVYGELCLSGDGVASGYLNRADLT 4388 Query: 2008 ASKFVDNPFMQGTKMYTTGDLARWLPNGELDVIGRLDNQVKIGGYRIELGEIESVAARHD 2067 KFV NPF KMY TGDLAR L +G +++ GR+D QVKI GYRIE EI+ +H+ Sbjct: 4389 EEKFVQNPFEPNKKMYRTGDLARRLSDGRIELAGRIDGQVKIRGYRIETEEIKRHLVKHE 4448 Query: 2068 KITQCVVAGQPNSLGSQDLVLYFVAAEKISTSELVNFLSPVLPKYMMPQMYIQIDEIPLT 2127 +I + V + + L Y + +S EL +L +P+YM+P ++Q++ IPLT Sbjct: 4449 QIKEAFVIDREGQDERRYLCAYITSQRDLSFEELRAYLKVEIPEYMIPSYFVQMERIPLT 4508 Query: 2128 ANGKTNLKALPKPGNVRPELRDDYEEAVTDLQKEIQQVWSLILNIEQVGIYDNFFEVGGN 2187 ANGK + KALP+P + DYE+ +++++ +VW IL ++ +GI NFF GG+ Sbjct: 4509 ANGKVDEKALPEPDVGKGV---DYEKPRNQVEEKLVKVWEDILGVKSIGISHNFFASGGD 4565 Query: 2188 SLKIVAMYNELQKLYPG-KIQITDIFSYPTISRLAQFID 2225 S+K + + + L + G +++ D+F+YP I L+ +++ Sbjct: 4566 SIKALQIISRLSR--EGITLEMKDLFTYPEIKFLSNYVN 4602 Score = 63.9 bits (154), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 74/307 (24%), Positives = 134/307 (43%), Gaps = 27/307 (8%) Query: 763 LDEEILRKAVVAILVHHDALRMVYK-RTPDGITQWNRSADCAGAAFTLDVYDLRGQD--- 818 +DE I ++ I+ H+ LR + + + + R + + DL +D Sbjct: 30 VDETIFEESFNEIMKRHEVLRASFNYKLDEPLHVILRDRKIKFSYNDVSNLDLNTKDLYV 89 Query: 819 EKRSIPALSDELQKGLDLEEGLLVKLGLFKTSLGDHLLV-AVHHLVIDGVSWRILIADLE 877 EK + D+ KG DL + L+++ L KT+ + ++ + HH+++DG I++ +L Sbjct: 90 EK----YIVDDKVKGFDLTKETLMRICLIKTNDNSYKVIWSFHHILLDGWCIGIILDELF 145 Query: 878 TAYRNIAAGAAASL--PPKTASYRSWAQKLKEYASGKVLLKEAEYWKGITNTGSGPLPKD 935 T Y + G L P + Y +W L + + L ++Y +G T + LPK Sbjct: 146 TIYSHKMKGEEHQLEDPRPYSDYINW---LNNQDNEEGLKYWSKYLEGYELTAT--LPK- 199 Query: 936 FGEENRGCGERMEVSLNFSKEQTAKLLRNCNTAYNTQINDVLLCSLGLAFKEWGGMDQLL 995 F + G +R E + FSKE T K+ + N N +N V+ GL ++ + ++ Sbjct: 200 FNNSSAGKYQRREKVIEFSKELTDKITQLANKN-NVTLNTVMQSIWGLILAKYNNSEDVV 258 Query: 996 VSLEGHGREEIFQGVSIDRTIGWFTTIFPVVLDMTRSHDLAYSLKRTKEMLRHVPHKGIG 1055 GR+ +G I+ +G F P + + S K KE+L+ H I Sbjct: 259 FGTVVSGRDAAVEG--IENMLGLFINTIPTRIKLQ-------SEKSFKEVLKATQHDAIE 309 Query: 1056 YGIWKYL 1062 + Y+ Sbjct: 310 GNDYNYI 316 >B3TLA3.1 B3TLA3_BACSU Iturin A synthetase C Length = 2605 Score = 1745 bits (4520), Expect = 0.0, Method: Compositional matrix adjust. Identities = 916/2247 (40%), Positives = 1381/2247 (61%), Gaps = 50/2247 (2%) Query: 11 FEKVIQKLNLKSDASRNPLFDVMFVLENLDYGLGPNEEQAKVKLIEPMAEVAKFDLTLTA 70 F+K+ +L L +A+ P+ D + LE + P+ IE A A F + Sbjct: 131 FDKMAGQLRLNYNANHLPIIDTVVSLEQIH----PD------GFIETAAADALFQFAM-- 178 Query: 71 KEAGGNL-DFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGGLDMLSNQEKHLL 129 G +L D L ++ +++++ + ++ H RL + P+ LG +++L E H L Sbjct: 179 ---GEDLIDIKLCFNEQVYDRQYMMQVLGHLNRLFSVILFQPELPLGQVNILPESETHSL 235 Query: 130 LNVFKGTPTDYPKDKTIHELFEEQADRTPDQLAVVCGGQALTYSELNEQANSLASVLREK 189 L + T+YP+DKT+++LFEEQ RTPDQ AV+ G + TY +LNE+AN LA LR+K Sbjct: 236 LVDNQTAKTEYPRDKTVYQLFEEQMKRTPDQAAVIYGEKQFTYRQLNERANQLARTLRKK 295 Query: 190 GVGAEAIVGIMADRSLELIIAILGTLKAGGAYLPIDPEYPADRINYMLTDSQAAMLLFQH 249 GV + + I+ + +EL++ IL LKAGGAY+PIDP+YP RI Y++ DSQA ++L Q Sbjct: 296 GVKTDRLTAIICEHEIELVVGILAVLKAGGAYVPIDPDYPKHRIQYIVEDSQADIVLTQS 355 Query: 250 HIVKDLTYAGGRLELENSELYIRETGNPVKASLPENLAYVIYTSGTTGTPKGVMVEHRNL 309 H+ K L AG + L+ Y + + S ++LAYVIYTSG+TG PKGV +EH+ L Sbjct: 356 HLQKQLELAGTMVFLDQESSYHEDGSDLEPISSTKDLAYVIYTSGSTGKPKGVAIEHQGL 415 Query: 310 VNYIHWANKRYVAGEQTAFPLYSSISFDLTVTSIYTPLISGNTIVIYDGEDKALLTRTIA 369 NYI WA++ YV GE+T FPLYSSI+FDLT+TS++TPLI+GN I++Y GE+ A L +I Sbjct: 416 TNYIWWASRVYVKGEKTNFPLYSSIAFDLTITSVFTPLITGNAIIVYGGENSAALLDSII 475 Query: 370 EENKVNIVKLTPTHLRLLEDMDL-SRSSIRTFIVGGEDLKIKVAEKIHRAFDGRIEIYNE 428 ++++ +I+KLTP HL+LL+++++ + +IR FIVGG++L ++A I F G+IEI+NE Sbjct: 476 QDSRADIIKLTPAHLQLLKEINIPAECTIRKFIVGGDNLSTRLARSISGKFGGKIEIFNE 535 Query: 429 YGPTEATVGCMIYKYNAERDKGTSVSIGIPADNTQLYIVGSRMELLPVGVAGELCIGGDG 488 YGPTE VGCMIY ++ + D+ SV IG ADN ++++ M+ +P GV GE+ I GDG Sbjct: 536 YGPTETVVGCMIYSFDPQNDRRESVPIGTAADNMNIFVLDKSMKPVPAGVPGEIYISGDG 595 Query: 489 VARGYLHKEALTAEKFVDHPFNAGSKLYKTGDMARWLSDGTVEYLGRMDNQVKIRGYRIE 548 +ARGYL++ LTAE+F+ HPF K+Y+TGD+AR L DG +EYLGR+D+QVKIRGYRIE Sbjct: 596 IARGYLNRAELTAERFLQHPFVPEVKMYRTGDLARRLPDGNIEYLGRIDHQVKIRGYRIE 655 Query: 549 TGEIENRLLQMPDITEAVVVARTDEQGHNYLCAYVVSNKEVIASEVKGRLSKELPNYMVP 608 GE+E+ Q+P I EA+V A+ + G LCAY + + A E++ LS++LP+YM+P Sbjct: 656 IGEVESAFFQIPPIQEALVTAQ-ETNGETSLCAYYTAQHSLTAGEIREHLSRQLPSYMIP 714 Query: 609 GFTVQIAKLPLSSNGKVDIKALPAVDISEMLAASYEAPNNKVEEILVDVWQRVLNIEPIG 668 + VQ+A +PL+SNGK+D +ALPA + Y AP ++E+IL VW+ VL E +G Sbjct: 715 AYFVQLAAMPLTSNGKIDRQALPA-PTGNLTGNPYTAPRTELEKILAGVWESVLGAEQVG 773 Query: 669 TNYNYYEMGGDSIKSILIVSALREHGLRLEVKDLMQYPSIKELAGYVKHEDVQAPQEAVE 728 + +++E+GGDSIKSI + S+L + G +L++K L ++P+I LA ++K A Q ++ Sbjct: 774 IDDHFFELGGDSIKSIQVTSSLYQAGYKLDIKHLFKHPTISGLAPFIKPVTRIAEQGEIK 833 Query: 729 GSVPFLPVQQWFFEQGLPQENHYNQAFMFYRKEGLDEEILRKAVVAILVHHDALRMVYKR 788 G P+Q WFF + P +HYNQ+ M Y KEGLDE L+K + I HHDALRMVY + Sbjct: 834 GRTLLTPIQHWFFARQYPDPHHYNQSVMLYFKEGLDESKLQKVMKKIAEHHDALRMVYVQ 893 Query: 789 TPDGITQWNRSADCAGAAFTLDVYDLRGQDE-KRSIPALSDELQKGLDLEEGLLVKLGLF 847 D + G F+LDV+ L ++ +I +++++Q+ + L +G L+KLGLF Sbjct: 894 G-DHEYEARTCGISEGELFSLDVFSLLEENNLAETIEMIANDIQQSIHLADGPLMKLGLF 952 Query: 848 KTSLGDHLLVAVHHLVIDGVSWRILIADLETAYRNIAAGAAASLPPKTASYRSWAQKLKE 907 + GDHLL+A+HHLV+DGVSWRIL+ D+ +AY + G A +LP KT SY WA++LK Sbjct: 953 QCQDGDHLLIAIHHLVVDGVSWRILLEDITSAYEQLQNGEAITLPKKTDSYLLWAERLKR 1012 Query: 908 YASGKVLLKEAEYWKGITNTGSGPLPKDFGEENRGCGERME-VSLNFSKEQTAKLLRNCN 966 YA + +YW + LPKD E+ G E E + + +++E+T +LL+ N Sbjct: 1013 YAESPEFEAKNQYWLEQKHISQHKLPKD-NEQETGLAEDQETIIVQWTEEETERLLKKSN 1071 Query: 967 TAYNTQINDVLLCSLGLAFKEWGGMDQLLVSLEGHGREEIFQGVSIDRTIGWFTTIFPVV 1026 AY T IND+LL LG+A W G +++ V LEGHGRE +FQ V I RT+GWFTT +PV Sbjct: 1072 RAYTTDINDLLLTGLGMAVHRWTGHEEIHVHLEGHGRESVFQDVDISRTVGWFTTQYPVS 1131 Query: 1027 LDMTRSHDLAYSLKRTKEMLRHVPHKGIGYGIWKYLADGNKELR-AFEPEVSFNYLGEFG 1085 L + D++ ++ KE LR +P KGIGYG+ KYL+D K PE+SFNYLG+F Sbjct: 1132 LQIQADRDISQRIRTVKEQLRQIPQKGIGYGLMKYLSDHPKASEWTGHPEISFNYLGQFD 1191 Query: 1086 REAGSSLLEFSRLSSGASISIDNNKLKGIDINGLIMEGELELVFSYSTLEYTRETVAQLT 1145 ++ + +E S S G S + +DING+I +G L L SYS +Y RET+ Sbjct: 1192 QDFENGGIEVSPYSGGKIASDRHPIAYTLDINGMISDGRLSLAISYSGKQYRRETMETCA 1251 Query: 1146 AAYHTSLLQVIDHCAHRQTAEKTPWDYGDPDLSLEDLDTLLACGQ---EIEKIHSLSPMQ 1202 A SL +VI+HCA ++ TP D D+++E+LD + Q +IE I+ L+PMQ Sbjct: 1252 ALLKNSLKEVIEHCAAQEHIHLTPSDISLKDITIEELDQFVKQTQHIGDIENIYPLTPMQ 1311 Query: 1203 EGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEILRTAFFYHDIKKFK 1262 +GM++++++D+ S YFEQ+ +++G L++E M L++L ++EILRT F+ + Sbjct: 1312 KGMLFHSLIDSASRAYFEQAAFDLKGDLDIEAFTMSLSQLAERHEILRTHFYTEWKDQPL 1371 Query: 1263 QAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDRSNPFDLEQDCLLRVAVLKTDTGNF 1322 Q V +++ + I EDI S ++++ +I F +D++ FDL QD L+RV++L+T+ Sbjct: 1372 QIVFRKKPIEITVEDIRSMKNKQRNEFIAGFVQKDKARGFDLTQDALMRVSILRTEDDQV 1431 Query: 1323 KVVYSFHHIIMDGWSAGIILQEVIAQYKARLQEAELKQEKAVPYSDYLDWLDHQDKAAAL 1382 ++++SFHHI+MDGW +I +EV Y L+ + ++E PYS Y++WL+ QD AL Sbjct: 1432 RLIWSFHHILMDGWCLPLITKEVFETYYELLERRQPEREAVTPYSRYIEWLEDQDHQNAL 1491 Query: 1383 DYWQSYLEAYESGTVI--PELQHQEKGFMHQQERTSLDAQATAKLKSLAEANGITLSSVI 1440 YWQ YL+ YE TV+ + +Q K + Q+ L Q + +++ A + +T+++ I Sbjct: 1492 AYWQKYLDGYEGQTVLLKEPVSNQAKKYQKQRLACRLGKQLSEEIRQTASKHHVTVNTFI 1551 Query: 1441 QTAWGVVLQKYSNTHDVVFGSVVSGRPSDIKGIERMVGLCINTVPVRVTGGDQLSFIALA 1500 Q+AWG++LQ+Y+N+ DVVFGSVVSGRP++I GIE MVGL INT+PVR+T ++ + Sbjct: 1552 QSAWGLLLQRYNNSQDVVFGSVVSGRPAEIPGIESMVGLFINTIPVRITAQPGMTVEQVL 1611 Query: 1501 KKLNKDFIHANAFSFCQLAEIQALSPMKNNLINHVVVYENYPVDQSLADLQEAEGREVKI 1560 K + + + A+ L EIQA + K LI+H++V+ENYPV++ + ++ + I Sbjct: 1612 KMSQEQALASQAYDTFPLYEIQAQTEQKQQLISHIMVFENYPVEKQMEHMKPNRD-ALDI 1670 Query: 1561 TAAQGFEQTNYDLEILIAPGRTLQIKITYNGCKYSRDVINALMDNLMHVLSCAVSNPDQA 1620 E T+YD ++ P + I YN Y + + ++ M ++ V++ Sbjct: 1671 INFHMEEHTHYDFNFIVMPAGEIDIHFVYNSNVYDHASVKRMEEHFMQIIKQMVNSQAIR 1730 Query: 1621 AESIDMVSEQERNKLLYELNCTGTAYAKEKTIAQLFEEQAERTPEAIALEFHGTVLSYRE 1680 + +D+++ ER+ L+ N T Y KEKT+ QLFEEQA+RTP+ A+ + + L+YRE Sbjct: 1731 VQDLDILTGDERSLLIEAFNDTEADYPKEKTLHQLFEEQAQRTPDQTAVVYGESQLTYRE 1790 Query: 1681 LNKRANQLARVLRRNSVGANVIVPILVKRSLNLLVGILGILKAGGGYLPLDTDYPVDRIH 1740 LN+RANQLAR L+ V + V I+ +RSL ++VG+ GILKAGG Y+P+D YPV+RIH Sbjct: 1791 LNERANQLARTLQSEGVQPDQPVGIMAERSLEMIVGLFGILKAGGAYVPIDPSYPVERIH 1850 Query: 1741 YMLQDSQASLLLTEKGLAAPLGLNEAVTILDIGSKQIQDEDDSNLQSITKADDLAYVLYT 1800 Y+L+DS LLL + L + V LD+ + ED SNL+ + LAYV+YT Sbjct: 1851 YILEDSDTKLLLAQSHLRKSVPFTGKV--LDLEDPRFSWEDGSNLKQTAGPNHLAYVIYT 1908 Query: 1801 SGSTGNPKGVAVEQRGVHNFIKGITDRISFTEDKIILSVTTCSFDIFGLESLLPLTRGLK 1860 SGSTG PKGV VE R V N + + + + +IL T +FD+ E G K Sbjct: 1909 SGSTGRPKGVMVEHRSVINRLVWMQEHYPLDKQDVILQKTPITFDVSVWELFWWSMTGSK 1968 Query: 1861 VVIASEEEQKDPHLLNKVILDSEVNTIQLTPSRLKLMLNC--SNTAESFKK----LKLMM 1914 V+ S +K+P ++ I V + P+ L L + E K+ LK + Sbjct: 1969 AVLLSNGGEKNPDVILDTIAQKNVTIMHFVPAMLHAFLESMEQKSDEELKRKLASLKYVF 2028 Query: 1915 IGGEGFPKDLLVQLQKFT----DSRIYNMYGPTETTIWSTVKELTHE---NSVNVGKPIA 1967 GE + + +++I N+YGPTE TI + E NSV +GKPI+ Sbjct: 2029 ASGEALTPAHVAGFHRMITPAGEAQIINLYGPTEATIDVSYFECEAGETLNSVPIGKPIS 2088 Query: 1968 NTQVYIVDQAG-HLAPIGVAGELCIAGDGVARGYLHKEELTASKFVDNPFMQGTKMYTTG 2026 N Q+YIV + P+GVAGELCIAGDG+ARGYL++ E TA KF +PF G +MY TG Sbjct: 2089 NIQLYIVQPGSEYFQPLGVAGELCIAGDGLARGYLNRPERTAEKFAAHPFEAGKRMYRTG 2148 Query: 2027 DLARWLPNGELDVIGRLDNQVKIGGYRIELGEIESVAARHDKITQCVVAGQPNSLGSQDL 2086 DLARWLP+G ++ +GR+D+QVKI GYRIELGEIE+ + D + + VV GS+ L Sbjct: 2149 DLARWLPDGNIEYLGRIDHQVKIRGYRIELGEIEASLLQLDAVKEAVVIAIEKE-GSKQL 2207 Query: 2087 VLYFVAAEKISTSELVNFLSPVLPKYMMPQMYIQIDEIPLTANGKTNLKALPKPGNVRPE 2146 Y E ++T++L L LP YM+P ++Q++++P+TANGK + KALP P R Sbjct: 2208 CAYLSGDESLNTAQLKRHLLNKLPAYMIPAYFVQVEKMPITANGKIDRKALPAPEGNR-L 2266 Query: 2147 LRDDYEEAVTDLQKEIQQVWSLILNIEQVGIYDNFFEVGGNSLKIVAMYNELQKLYPGKI 2206 +Y T ++K++ +W IL + GI D+FF+VGG+SLK++ + +++ + Sbjct: 2267 TGTEYTAPGTLIEKQLADIWKDILALPDPGIKDHFFDVGGHSLKVLQLIDQINAGMGLNM 2326 Query: 2207 QITDIFSYPTISRLAQFIDNQSAFAEA 2233 ++ +PTI +A+ I Q+A E+ Sbjct: 2327 HYQAVYDFPTIETMARAI--QAAVFES 2351 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.135 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 14,275,259,762 Number of extensions: 617544183 Number of successful extensions: 1809463 Number of sequences better than 1.0e-05: 16613 Number of HSP's gapped: 1668197 Number of HSP's successfully gapped: 38897 Length of query: 2444 Length of database: 3,060,696,203 Length adjustment: 153 Effective length of query: 2291 Effective length of database: 1,619,280,908 Effective search space: 3709772560228 Effective search space used: 3709772560228 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 140 (58.5 bits)