BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0382.0030.p (1606 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C3HA41.1 C3HA41_BACTU Beta-ketoacyl synthase 1964 0.0 B8I5H4.1 B8I5H4_CLOCE Beta-ketoacyl synthase 1098 0.0 B8I5H5.1 B8I5H5_CLOCE Amino acid adenylation domain protein 1086 0.0 B8I5I0.1 B8I5I0_CLOCE Condensation domain protein 998 0.0 C3HA42.1 C3HA42_BACTU Beta-ketoacyl synthase 982 0.0 >C3HA41.1 C3HA41_BACTU Beta-ketoacyl synthase Length = 1609 Score = 1964 bits (5087), Expect = 0.0, Method: Compositional matrix adjust. Identities = 961/1625 (59%), Positives = 1242/1625 (76%), Gaps = 35/1625 (2%) Query: 1 MKNGFISLKELKASAFTASTLESEDRLLRDS-AVKPMSESDIAIIGMSGKFGEANDLRAF 59 MK FISL +LK+S F LE +++ ++ + +SE+DIAIIG+SGKFG+AN+L + Sbjct: 1 MKTDFISLSDLKSSVFKNDKLEIKEKQRKEVIGINNISETDIAIIGISGKFGKANNLNDY 60 Query: 60 WEVLLKGKECIREIPLHRKADADRYLEFSGGKSPHEDTQYTRIAYLDEIDKFDCGFFGIL 119 W++L+ +E IR+IP++RK DAD YLE+SG K+ ++D YT+IAYLDEI+KFDC FF I+ Sbjct: 61 WDLLINEEELIRDIPINRKKDADNYLEYSGIKNKNKDVNYTKIAYLDEINKFDCDFFEII 120 Query: 120 PNEAKLIDPRQRLFLESAWSTLEDAGYGGGKLCGSKTGVYVGLSSDGXXXXEYFKLIEQG 179 PNEAKLIDPRQRLF+E+AW+ LEDAGYGGGKLCG+KTG+YVGLSSDG EYFKLIE+G Sbjct: 121 PNEAKLIDPRQRLFVETAWNALEDAGYGGGKLCGTKTGIYVGLSSDGSN--EYFKLIEKG 178 Query: 180 DPSLIGLSTAGNIKSVIAGRLAYILDFKGPSMMIDTACSSSLVALHVACQAIKNHECEAA 239 D SL+GL+TAGNIKSVIA RLAYILDFKGP+M+IDTACSSSLV LH ACQA++N +C+ A Sbjct: 179 DQSLLGLATAGNIKSVIASRLAYILDFKGPTMVIDTACSSSLVTLHTACQALRNRDCDTA 238 Query: 240 LVGGVNIKIFPKTEEENNLNIGITSSDSSIRTFDDQADGTNSGEGVAAVLIKPLDKAIRD 299 LVGGVNIK+FPKTEEEN NIGITSSDS ++TFD++ADGTNSGEGVAA+L+KPL AI D Sbjct: 239 LVGGVNIKVFPKTEEENKWNIGITSSDSIVKTFDNEADGTNSGEGVAAILLKPLKNAILD 298 Query: 300 RDHIYAVIKGSAVNQDGSSVGITAPNMTAQENVITDAWKEARIDPQTVTYWEAHGTGTKL 359 +D IYAVIKGSA+NQDGSSVGITAPN+TAQENVI DAWK+A IDP+T+TY EAHGTGTKL Sbjct: 299 KDQIYAVIKGSAINQDGSSVGITAPNVTAQENVILDAWKDAHIDPKTITYIEAHGTGTKL 358 Query: 360 GDPIEVHAIHRAFNRFTDRKQFCAIGSVKTNIGHLDSLAGLAGLIKAVMAIQYRKIPPSL 419 GDPIEV AI +AF++FTDRKQFCAI SVKTNIGHLDSLAGLAGLIKAVMA++++KIPPSL Sbjct: 359 GDPIEVSAIQQAFSKFTDRKQFCAISSVKTNIGHLDSLAGLAGLIKAVMALKHKKIPPSL 418 Query: 420 HFKVPNRNIQFSSSPVYVNDQTTDWKGYDGVYRCGISSFGLSGTNAHVVLEGPPPLEQRQ 479 +FKVPNRNI F SPVYVND+ DW DGVYRCG+SSFGLSGTN HV+LE P +EQ + Sbjct: 419 NFKVPNRNINFHESPVYVNDRVQDWINNDGVYRCGVSSFGLSGTNCHVILEEAPKIEQHE 478 Query: 480 DEVPANHIFTVSAKTEASLEKLILNYLEFLGKEQELRISDLCYTVNTGRLPNQCRIAMIV 539 + V + +IFTVSA+T+ SL L+ Y+EFLGKE+E+++ D+CYTVNTGRL N+ R+A+I+ Sbjct: 479 ETVFSENIFTVSARTKKSLFNLLNRYVEFLGKEKEVKLHDICYTVNTGRLANKFRLALII 538 Query: 540 SSTEELIRKLKLLARNGAGTYKAEDIYYRKLERNLKFIGKSMTGSGGLTES--------- 590 + EEL+ KL+LL R+ TY +DIY++ +E+N +FIG+S+ + + ES Sbjct: 539 KTKEELLEKLELLVRSEWKTYPDKDIYFQMIEKNTRFIGRSIFFT-RINESHTSHQIKRI 597 Query: 591 --------SHKSIADLQLLCGAYCDGADMDFEGIYRQLDCRKVSWPTYAFEQKRLWVELP 642 +H + DLQ L YC+GAD++FE +YRQ + +KVS PTY+F+ KRLW++L Sbjct: 598 INRIRKDITHINKCDLQFLSEVYCNGADVNFEELYRQFNFQKVSLPTYSFDGKRLWIDLK 657 Query: 643 ESRRSLTAARTRHPLLQERAVSSLNLEVYVSYLNVQDFWVLNEHQVNDACVIPGTAYLDM 702 E S+++ + +HPL+ + S N+EVYVS+LNV+D W+LNEH+V ++ V+PGT Y+D Sbjct: 658 EKSNSISSEKDKHPLINNLVLQSFNMEVYVSHLNVKDHWILNEHKVENSYVVPGTTYIDT 717 Query: 703 AKEIGTRHFGEARDIILSDVSFLNLLKVEKDEVKEIHTIVNIKDDALKFTVASRASAAEE 762 A+EIG R+FG++ +I+L +V F +LL+V+ E +E+HTI+NIK+DAL+F+V S+ E Sbjct: 718 AREIGKRYFGDSWNIVLKNVMFPHLLQVKDVETREVHTIINIKEDALEFSVVSKLGEV-E 776 Query: 763 WIKHAEAWIGRKERQPHTTYDIETLKTTYDSVYAIRR-NQSWPVIEESSYTSVQYVEDTN 821 W+KHAEA I ++ ++ YDIE LK Y+SVY I++ N+S + + Y SV ++EDTN Sbjct: 777 WVKHAEALIVKEVKERPKKYDIEVLKKNYESVYIIQKNNRSLVDVNQKDYESVYFIEDTN 836 Query: 822 RPESIINVGGRWKCTNAIYRSKEGVLCELEIQAEYAEDLEQFYLHPAMMDCAVNAGTFTI 881 R ESI++VG RWKCTNAIYR+ EGVLCELEI+ EY D + + LHPAMMDCAVNA TFTI Sbjct: 837 RSESIVSVGDRWKCTNAIYRNSEGVLCELEIKKEYQNDFDCYSLHPAMMDCAVNAATFTI 896 Query: 882 NEDTYLPYYYKEFRIFGPTPKKFYSYITKKNNENEETGKFDLLLLNEQGEVFGEISSYIV 941 N+++YLPYYYK FRIFG TPKKFYSYITKK N+NEETGKFD+LLLNE GEVFGEIS+YIV Sbjct: 897 NDESYLPYYYKNFRIFGSTPKKFYSYITKKTNDNEETGKFDILLLNEAGEVFGEISNYIV 956 Query: 942 KRVHSFTPLEQPSAQKSIYHKLGWVEKNEYKLLRRSEANGGILLFHNQAKLAGEIIASLR 1001 K+VH T E+ K +YHKL WV K +Y +L R N ILLF N+ +L+ +I LR Sbjct: 957 KKVHGST--EKIDKSKQMYHKLAWVSKKDY-ILERKYDNRNILLFKNEGELSNKIAKQLR 1013 Query: 1002 QAGKKVIEAIPGQAFSERGEQAYSLGGRQEDYDKLFAAIELQKISQIIHLMTIQDHSAEG 1061 GK VIE G+ FS+ Y++ G QEDYDKLF AIE + I+QIIHLMTI + + E Sbjct: 1014 VDGKSVIEVELGKQFSKISNWKYTIRGEQEDYDKLFEAIENENINQIIHLMTINNETDE- 1072 Query: 1062 GHQQLEYNLKLGLDSLFYLSQSIMKHPNDPVELVLFAEHVHRISGSETAVNPHHAAFFGL 1121 QL+ L +GL+SLFYL++SIMK+ + +EL+LF + HR++G E + PH+AAFFG Sbjct: 1073 ELLQLQKKLSIGLESLFYLTKSIMKNTKNSMELLLFTDFAHRVNGEEFKIKPHNAAFFGF 1132 Query: 1122 GKVLGKEYSKLNVRCIDIDGETRAAECIREINGEKQVELVGYREGRPYVQELQAVPVPAL 1181 GKV+ KEY KL+VRCIDID + +CI EIN +KQVELV YR+ YVQELQ V + AL Sbjct: 1133 GKVIEKEYPKLSVRCIDIDDKICVEDCITEINSKKQVELVAYRDKDKYVQELQNVDIKAL 1192 Query: 1182 PDQQAEIKKDGVYIITXXXXXXXXEVARYLSSLAKVNLILVGRSGLSHPIDPGSKNHTRT 1241 P+++ E KKDGVY+IT E+A+Y+SS VNLIL+GRSGLS SK + Sbjct: 1193 PEEKVEFKKDGVYVITGGMGGIGLEMAKYISSKENVNLILIGRSGLSATASEKSKIAYKI 1252 Query: 1242 EIMNHIRANGSNVDCYQADVADEREMQAMLAQLRQRYTSINGIFHCAGVAGEGFIFRKDK 1301 + +N I+ +GS V+CY+A+VA+E E++ + ++R+++ I+G+ H AGV+GEGFIFRK+K Sbjct: 1253 KTINEIQESGSRVECYKANVANEHEIKEVFREIRKKFNKIDGVIHGAGVSGEGFIFRKEK 1312 Query: 1302 AAFDRVTRPKIQGTRILDKLTAEDKLDFFVMFSSITSLSGSMGQADYTAANAYLDSYAEY 1361 FD V +PKI GT I+++LT +D+LDFF+MFSSITSL GSMGQADY AANAY+DS+ E+ Sbjct: 1313 EVFDNVIKPKIHGTWIMNQLTKDDQLDFFIMFSSITSLGGSMGQADYAAANAYMDSFEEF 1372 Query: 1362 RSLIKPEQKTLTINWCGWKDTGMLADYRNKLGKEAGTEENQNEQGFKNIGTREAIEALNV 1421 RSL+ PEQKTLTINWCGW D GMLA+Y +K EE+++ GFK I + EAI + Sbjct: 1373 RSLVVPEQKTLTINWCGWNDVGMLAEYIDK-----RKEEHKDNNGFKTINSIEAIYTFDE 1427 Query: 1422 VLNKEISKVIIGELDDKVFGLYKDQITFSLAPEIAARIRPTRPKAPGHTGLPPVPMEHRD 1481 ++ KEISKVIIGE+D KV G++K I F ++ +I RI T K + V + H D Sbjct: 1428 IIQKEISKVIIGEIDYKVLGVHKGLIKFLISSDILQRIDQTVSKEKISEEMNFVRVNHID 1487 Query: 1482 YSGIESAIVKAWVKVLGLEQININDKFYDLGGDSISAIYLVKEIGKVFPSLIDISDIFTY 1541 Y+ IE+ I+K W+KVLGLEQI I+DKFYDLGGDSISAIYL+KEI K FPS ID+SDIFTY Sbjct: 1488 YNSIENKILKVWIKVLGLEQIGIDDKFYDLGGDSISAIYLMKEIEKEFPSRIDVSDIFTY 1547 Query: 1542 PSISEMSDYIQSLLEDRNGHAAGSVQPVTSEEETEEDLDGILSKLASGELEVSEANQLLY 1601 PSI EM+ YI+S L++ + + + E+D+D ILSKLASGELEV EAN+L+Y Sbjct: 1548 PSIREMALYIESELKNDDDCVPSQ---IFEDHHKEDDIDTILSKLASGELEVGEANKLIY 1604 Query: 1602 SGQKS 1606 SGQKS Sbjct: 1605 SGQKS 1609 >B8I5H4.1 B8I5H4_CLOCE Beta-ketoacyl synthase Length = 1613 Score = 1098 bits (2840), Expect = 0.0, Method: Compositional matrix adjust. Identities = 631/1641 (38%), Positives = 935/1641 (56%), Gaps = 126/1641 (7%) Query: 26 RLLRDSAVKPMSESDIAIIGMSGKFGEANDLRAFWEVLLKGKECIREIPLHRKADADRYL 85 RLL+D ++ S++DIAI+GM+ K A ++ FW + G++C+ + P RK D D L Sbjct: 27 RLLKDDEIR--SDNDIAIVGMAAKLPFAPNIDEFWINIRNGRDCVSDFPEERKKDTDALL 84 Query: 86 EFSGGKSPHEDTQYTRIAYLDEIDKFDCGFFGILPNEAKLIDPRQRLFLESAWSTLEDAG 145 K P E +Y+ A+LDE+DKFD FF + P EA LIDP QRLFL++A+ +ED+G Sbjct: 85 GHMNLK-PSE-IEYSIGAFLDEVDKFDYKFFKLSPKEASLIDPNQRLFLQTAYQAIEDSG 142 Query: 146 YGGGKLCGSKTGVYVGLSSDGXXXXEYFKLIEQGDPSLIGLSTAGNIKSVIAGRLAYILD 205 YG G+L GSKTGVYVG SSD Y + I DP L G++ GNIKS+IA R++Y LD Sbjct: 143 YGNGRLSGSKTGVYVGYSSD--FGESYKRFIHTVDPGLSGIAIPGNIKSIIASRISYYLD 200 Query: 206 FKGPSMMIDTACSSSLVALHVACQAIKNHECEAALVGGVNIKIFPKTEEENNLNIGITSS 265 KGPSM++DTACSSSLVA+H+AC+AI+N ECE AL GGV + + P + IGITSS Sbjct: 201 LKGPSMLVDTACSSSLVAIHMACRAIRNGECETALAGGVKLNLLPLKINRQD-GIGITSS 259 Query: 266 DSSIRTFDDQADGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGSAVNQDGSSVGITAPN 325 D R+FDD +DGT GEG AA+L+KPL KAI DRD++YAVIKGSA+NQDG+S+GITAPN Sbjct: 260 DGKARSFDDSSDGTGIGEGCAAILLKPLKKAIADRDNVYAVIKGSAINQDGNSIGITAPN 319 Query: 326 MTAQENVITDAWKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHRAFNRFTDRKQFCAIG 385 AQE VI AWK+A ++P+T++Y EAHGTGTKLGDP+E+ I AF R+TD+KQFCA+G Sbjct: 320 SAAQEEVIVKAWKDAGVNPETISYIEAHGTGTKLGDPLEIDGIESAFKRYTDKKQFCALG 379 Query: 386 SVKTNIGHLDSLAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQFSSSPVYVNDQTTDWK 445 +VKTNIGHLD+ +G+AG+IK VMA+ +++PP LHFK PNR SPVY+ND+ T W+ Sbjct: 380 TVKTNIGHLDNASGMAGVIKMVMALTNKELPPMLHFKRPNRKTNIQESPVYINDRLTQWE 439 Query: 446 GYDGVYRCGISSFGLSGTNAHVVLEGPPPLEQRQDEVPA--------NHIFTVSAKTEAS 497 RCGISSFGLSGTN H++LE P E+ Q PA ++ T+SA ++ Sbjct: 440 TDGFPRRCGISSFGLSGTNCHMILEEAPSSEKPQ--YPAEESIIPYRKNVLTISANHVSA 497 Query: 498 LEKLILNYLEFLGKEQELRISDLCYTVNTGRLPNQCRIAMIVSSTEELIRKLKLLARNGA 557 L+ I Y L + + + D+CYT NTGR RIA+I + ++L +KL L + Sbjct: 498 LQSYIEAYRHMLDNIKNVTLEDICYTANTGRTHFPVRIAIITTDIKDLKQKLAFLTGSIK 557 Query: 558 GTYKAEDIYYRKLERNLKFIGKS--------------MTGSGGLTESSHKSIADLQLLCG 603 + IY K E G S +T + G + H L +C Sbjct: 558 YNIDTKCIYSAK-EYATDHPGISTFENLTPEADTLPDLTSASGDIYNKH-----LDEICK 611 Query: 604 AYCDGADMDFEGIYRQLDCRKVSWPTYAFEQKRLWVELPESRRSLTAA------RTRHPL 657 +Y G + ++ +Y +KVS PTY FE+ R W+ + + A + +PL Sbjct: 612 SYISGDHIQWDKVYDGKGMKKVSLPTYPFERLRCWLTANTPKAAEINAYEQSYNKLGYPL 671 Query: 658 LQERAVSSLNLEVYVSYLNVQDFWVLNEHQVNDACVIPGTAYLDMAKEIGTRHFGEARDI 717 L + ++ VY + V WVLNEH+VN ++PGT+Y++M E H+ ++ Sbjct: 672 LDSCSTETMEGAVYSTNFQVNRHWVLNEHKVNGNFIVPGTSYIEMVSE-AVGHYKYYENL 730 Query: 718 ILSDVSFLNLLKVEKDEVKEIHTIVNIKDDALKFTVASRASAAEEWIKHAEAWIGRKERQ 777 D+ F L V ++E +++ T++ I+D L F VASR ++W++H + + E + Sbjct: 731 EFRDIIFEFPLAVGENEARDVQTVLKIEDGYLGFYVASRPD-GDKWVRHVQGKVFLDEDR 789 Query: 778 PHTTYDIETLKTTYDSVYAIRRNQSWPVIEESSYTSVQYVEDTNRPESIINVGGRWKCTN 837 Y+ + + + + EE +E T + + +I+ G RW Sbjct: 790 NSVQYNPDEMARS-------------AIFEED-------IELTGKRKGLIDTGPRWNNLK 829 Query: 838 AIYRSKEGVLCELEIQAEYAEDLEQFYLHPAMMDCAVNAGTFTINEDTYLPYYYKEFRIF 897 +Y +GVL L + E+ DL++ +HPA+MD AVN +I E YLP+ YK I+ Sbjct: 830 KVYTLHDGVLAYLVLPDEFTGDLDKCIIHPALMDSAVNVAIGSIGEGLYLPWSYKSLIIY 889 Query: 898 GPTPKKFYSYITKKNNE--NEETGKFDLLLLNEQGEVFGEISSYIVKRVHS-FTPLEQPS 954 G P K YS I +K N ET FD++L++E+G VF +I +Y +K+V+ T + S Sbjct: 890 GKMPDKLYSLIRQKGKADLNMETASFDIILMDEKGRVFADIENYTLKKVNQLLTTPDYKS 949 Query: 955 AQKSIYHKLGWVEK----------NEYKLLRRSEANGGILLFHNQAKLAGEIIASLRQAG 1004 + +++H++ W++ N YK A G +LLF ++ L +I +L G Sbjct: 950 VKVNMFHRMNWIKNYTTKGVESIHNAYK-----PAAGKVLLFKDRGSLWMDIKETL---G 1001 Query: 1005 KKVIEAIPGQAFSERGEQAYSLGGRQEDYDKLFAAIELQKISQIIHLMTIQDHSAEGGHQ 1064 V+E + + YS+G +EDYD+L + + ISQIIHL +I Sbjct: 1002 VDVVEVDICGCYEKFATGRYSIGYGEEDYDRLIKDLREEGISQIIHLSSIGWEKLPEDSD 1061 Query: 1065 QLEYNLKLGLDSLFYLSQSIMKHP-NDPVELVLFAEHVHRISGSETAVNPHHAAFFGLGK 1123 L K GL SL YL +S++ + + VEL+ +++V+ ++G E +N ++A G+ Sbjct: 1062 SLAETQKRGLYSLVYLIRSLISNKIRNEVELIAVSDYVNMVTGMERRINYYNATIPGICT 1121 Query: 1124 VLGKEYSKLNVRCIDIDGETRAAECIREINGEKQVELVGYREGRPYVQELQAVPVPALPD 1183 V G+EY L RCIDID T + + E+N L+ YR+G Y QE+ V + Sbjct: 1122 VAGQEYGNLKCRCIDIDETTEVNKLVSELNSRDSCSLIAYRDGERYHQEMDEVHLEDSEP 1181 Query: 1184 QQAEIKKDGVYIITXXXXXXXXEVARYLSSLAKVNLILVGRSGLSH--------PIDPGS 1235 ++ EI + GVYIIT E A YLS+ V+L+L+ R+ + + G+ Sbjct: 1182 EEIEICEKGVYIITGGLGGIGREFAGYLSAKKPVSLVLIARTYIPDREAWDEILKKNSGT 1241 Query: 1236 KNHTRTEIMNHIRANGSNVDCYQADVADEREMQAMLAQLRQRYTSINGIFHCAGVAGEGF 1295 + E + I +GS V Y ADV++E +M+ +L+ +R++Y ING+ H AG+AG GF Sbjct: 1242 MLAQKIEFIKDIEKSGSQVVYYSADVSNENDMKNVLSSIRRKYGRINGVIHAAGIAGNGF 1301 Query: 1296 IFRKDKAAFDRVTRPKIQGTRILDKLTAEDKLDFFVMFSSITSLSGSMGQADYTAANAYL 1355 I RKD F RV +PK+QGT ILDKLT ED LDFF+MFSSI S+ G GQ+DYTAAN+++ Sbjct: 1302 IIRKDMEIFTRVVKPKVQGTFILDKLTKEDNLDFFIMFSSINSILGGAGQSDYTAANSFM 1361 Query: 1356 DSYAEYRSLIKPEQKTLTINWCGWKDTGMLADYRNKLGKEAGTEENQNEQGFKNIGTREA 1415 DS+A+YR KT++INW WK+TGM D GK G F T +A Sbjct: 1362 DSFADYRRKTAG-GKTVSINWTAWKETGMAFDNGIINGKIRGV--------FLPATTSDA 1412 Query: 1416 IEALNVVLNKEISKVIIGELDDKVFGLYKDQITFSLAPEIAARIRPTRPKAPGHTG---- 1471 I+ + K+++++I G+LD + L + +I +I + ++ + Sbjct: 1413 IQMFEEITAKKLTRIIAGQLDFETIPLLDSGTAIRFSNKIQGKIHKYKVRSNTDSQRNTA 1472 Query: 1472 ----LPPVPM---EHRDYSGIESAIVKAWVKVLGLEQININDKFYDLGGDSISAIYLVKE 1524 + P+ + + + S +++ + + W LGLE++++ D F DLGGDS+ A L+K Sbjct: 1473 REGEITPLKIKGSKDKGISSVQAVVARIWAGALGLEEVSVYDNFNDLGGDSVMATLLLKN 1532 Query: 1525 IGKVFPSLIDISDIFTYPSISEMSDYIQSLLEDRNGHAAGSVQPVTSE-----EETEEDL 1579 + K FP ++DISDIF YPSIS MS+YI+S R G +QP E+ E + Sbjct: 1533 LEKEFPGIVDISDIFNYPSISAMSEYIES----RTGKE--KIQPDVENQQIMTEDGEAGM 1586 Query: 1580 DGILSKLASGELEVSEANQLL 1600 + I+ +L+ GE+ + E ++L+ Sbjct: 1587 EEIMQQLSRGEITIEEVDKLM 1607 >B8I5H5.1 B8I5H5_CLOCE Amino acid adenylation domain protein Length = 3695 Score = 1086 bits (2808), Expect = 0.0, Method: Compositional matrix adjust. Identities = 600/1602 (37%), Positives = 924/1602 (57%), Gaps = 113/1602 (7%) Query: 28 LRDSAVKPMSESDIAIIGMSGKFGEANDLRAFWEVLLKGKECIREIPLHRKADADRYLEF 87 L++ + + +S D+AIIG+SGKF ++ F+ L G + + P RK D D L + Sbjct: 19 LKNISFEEVSTQDVAIIGISGKFASCGNMDEFYVSLRNGDNLVGKFPQRRKQDIDTILRY 78 Query: 88 SGGKSPHEDTQYTRIAYLDEIDKFDCGFFGILPNEAKLIDPRQRLFLESAWSTLEDAGYG 147 G ++T Y A+L+EIDKFDC F I P EA L+DP QRLFL++AW+ +ED+GYG Sbjct: 79 MG--ISEKETVYYEGAFLNEIDKFDCSLFNISPKEAGLMDPNQRLFLQTAWNAIEDSGYG 136 Query: 148 GGKLCGSKTGVYVGLSSDGXXXXEYFKLIEQGDPSLIGLSTAGNIKSVIAGRLAYILDFK 207 G +L S+TGVYVG D +Y K ++ DPS+ LS GNIKS++A R++Y+LD K Sbjct: 137 GDRLRSSRTGVYVGYCGD--FNEDYRKYVQLMDPSMAALSVTGNIKSIVASRISYLLDLK 194 Query: 208 GPSMMIDTACSSSLVALHVACQAIKNHECEAALVGGVNIKIFPKTEEENNLNIGITSSDS 267 GPSM++DTACSS+LVA+H+ACQA++ ECE A+ GGV + + P N IGI SS Sbjct: 195 GPSMLVDTACSSTLVAIHLACQALRKGECETAIAGGVKLILLPVDNNPQN-GIGIESSSG 253 Query: 268 SIRTFDDQADGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGSAVNQDGSSVGITAPNMT 327 R+FD+ +DGT GEGVAA+++KPL KAI DRD+IY++IKGSAVNQDG+S+GIT PN Sbjct: 254 VTRSFDEYSDGTGFGEGVAAIVLKPLKKAIEDRDNIYSIIKGSAVNQDGTSMGITVPNAQ 313 Query: 328 AQENVITDAWKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHRAFNRFTDRKQFCAIGSV 387 AQ +VI AWK+A+IDP+T++Y EAHGTGT LGDP+E+ I AF ++T++KQFCA+ SV Sbjct: 314 AQSDVIIRAWKDAKIDPETISYIEAHGTGTNLGDPVEIDGIEMAFAQYTNKKQFCAVSSV 373 Query: 388 KTNIGHLDSLAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQFSSSPVYVNDQTTDWKGY 447 KTNIGHLDS AG+AGL+KAV++++++++ PSLHF PN+ I F +SPVY+ND W+ + Sbjct: 374 KTNIGHLDSAAGIAGLLKAVLSLKHKELFPSLHFDRPNQKINFQNSPVYINDSLEQWENH 433 Query: 448 DGVYRCGISSFGLSGTNAHVVLEGPPPLEQRQDEVPA--NHIFTVSAKTEASLEKLILNY 505 G RCGISSFGLSGTN H+VLE PP ++ +E P HIFT+S++ L + + NY Sbjct: 434 GGPRRCGISSFGLSGTNCHLVLEEPPQIKSIPEESPGCNYHIFTLSSQNINGLMEQLKNY 493 Query: 506 LEFLGKEQELRISDLCYTVNTGRLPNQCRIAMIVSSTEELIRKLKLLARNGAGTYKAEDI 565 ++L +E+E+ + LC T NTGR R+A +++S EL K++ L+ G ++ + Sbjct: 494 EKYLNREREVSLGSLCSTTNTGRGHYNFRLAFVITSKNELKEKIQKLSTGGLENFEKYGV 553 Query: 566 YYRKLERNLKFIGKSMTGSGGLTESSHKSIADLQL-----------------------LC 602 Y+ K K + K G E S + IADL L +C Sbjct: 554 YFGK----HKIVDKEKESRGN-NEYSQEEIADLSLQTETYLNEAINNESQQKKVSLENIC 608 Query: 603 GAYCDGADMDFEGIYRQLDCRKVSWPTYAFEQKRLWVELPESRRSLTAARTRHPLLQERA 662 Y +GA++ + +Y+ KVS P Y+F +KR W+E S + ++HPL+ + Sbjct: 609 ALYVNGANVQWNRLYKSGSYAKVSLPGYSFMKKRCWIEHENS----NSHNSKHPLIDKHI 664 Query: 663 VSSLNLEVYVSYLNVQDFWVLNEHQVNDACVIPGTAYLDMAKEIGTRHFGEARDIILSDV 722 + S++L+V+ + V WVLNEHQ+ V PGT YL+M +E +HFG + + V Sbjct: 665 LESVDLDVFSTTFKVDRQWVLNEHQIGSNYVAPGTTYLEMIREASRKHFGN-HPLKMQQV 723 Query: 723 SFLNLLKVEKDEVKEIHTIVNIKDDALKFTVASRASAAEEWIKHAEAWIG--RKERQPHT 780 +F++ L ++ DE KE+HTI+ +D L++T+AS+ +W+KH+ + KE Sbjct: 724 TFIHPLILKADEEKEVHTIIKRDEDTLEYTIASKQKENGQWLKHSTGAVAGIPKEDASSL 783 Query: 781 TYDIETLKTTYDSVYAIRRNQSWPVIEESSYTSVQYVEDTNRPESIINVGGRWKCTNAIY 840 ++D E +K +V I S E I+ +G RW A+Y Sbjct: 784 SFDFEKIKEACPNVIDIGNMGS--------------------REGILRLGPRWDTLKAMY 823 Query: 841 RSKEGVLCELEIQAEYAEDLEQFYLHPAMMDCAVNAGTFTINEDTYLPYYYKEFRIFGPT 900 L E+ EY+EDL +++++P++MDCAVN ++ E YLP Y +I+ Sbjct: 824 TGDRMALACFELGEEYSEDLSKYHMYPSLMDCAVNIANMSVGEGLYLPLSYGSLKIYETL 883 Query: 901 PKKFYSYITKKNNE--NEETGKFDLLLLNEQGEVFGEISSYIVKRVHSFTPLEQPSAQKS 958 P+ FYSY+ +K+N N E FD+ L++E G+ EI Y VK+VH+ T LE + Sbjct: 884 PRSFYSYLVRKDNMSLNNEIAIFDIKLMDEYGKALAEIEDYSVKKVHN-TGLEAEDPD-N 941 Query: 959 IYHKLGWVEKNEYKLLRRSEAN--GGILLFHNQAKLAGEIIASLRQAGKKVIEAIPGQAF 1016 +++K GW EK E + L A+ G ++F+++ + E+ LR AG + +E G F Sbjct: 942 LFYKTGW-EKQEQEFLTGENADFSGVTIIFNDEYGMGEELAQKLRAAGTETVEVEFGIDF 1000 Query: 1017 SERGEQAYSLGGRQEDYDKLFAAIELQKISQIIHLMTIQ---DHSAEGGHQQLEYNLKLG 1073 + Y G + D+ KLF+ + + +++II+L + D +G + +E G Sbjct: 1001 RQINHSKYMTGTDEGDFRKLFSELNGRAVNRIIYLSALNFDTDMDIDGLDEAMER----G 1056 Query: 1074 LDSLFYLSQSIMKHPNDPVELVLFAEHVHRISGSETAVNPHHAAFFGLGKVLGKEYSKLN 1133 + +L L+++I + + ++LV+ A++ + + +N + + +G+V+G+EY + Sbjct: 1057 VYNLHRLTKAISESMQNDLDLVIIADNASEVVEYQEKINALSGSLYAMGRVIGQEYDNIR 1116 Query: 1134 VRCIDIDGETRAAECIREINGEKQVELVGYREGRPYVQELQAVPVPALPDQQAEIKKDGV 1193 RCIDID I E+ +K + V YR G+ Y+Q LQ + + +I+++GV Sbjct: 1117 CRCIDIDKAVDTDLIISELAQKKFLFNVSYRNGQRYIQNLQRQSPYSNGGDKIQIREEGV 1176 Query: 1194 YIITXXXXXXXXEVARYLSSLAKVNLILVGRSGLSHP--IDPGSKNH------------T 1239 YI+ E+ RYL++ +VNL+++ RS L D KN Sbjct: 1177 YIVAGGLGGIGLEICRYLAAEKRVNLVMINRSPLPERSLWDDLLKNTYEGINDTDYNIID 1236 Query: 1240 RTEIMNHIRANGSNVDCYQADVADEREMQAMLAQLRQRYTSINGIFHCAGVAGEGFIFRK 1299 R + + ++ GS V C+ AD+AD ++ +L ++R+ + +ING+ + AGV EG + +K Sbjct: 1237 RIQSIKELKDMGSKVLCFSADLADMASVRLVLDEVRKHHANINGVINLAGVFEEGILIKK 1296 Query: 1300 DKAAFDRVTRPKIQGTRILDKLTAEDKLDFFVMFSSITSLSGSMGQADYTAANAYLDSYA 1359 D A RV PK+ GT ILD+LT D LDFFVMFSSI S G GQ +Y+AANA++DS+A Sbjct: 1297 DTEALKRVIAPKVNGTLILDRLTENDNLDFFVMFSSIASFIGGHGQGEYSAANAFMDSFA 1356 Query: 1360 EYRSLIKPEQKTLTINWCGWKDTGMLADYRNKLGKEAGTEENQNEQGFKNIGTREAIEAL 1419 EY++ + +K ++INW GW GM + Y G+ FK I +AI+A Sbjct: 1357 EYKN--RTGRKVISINWTGWNQVGMASQYNLSDGRRI----------FKLISKEKAIKAF 1404 Query: 1420 NVVLNKEISKVIIGELDDKVFGLYK-DQITFSLAPEIAARIR-----PTRPKAPGHTGLP 1473 + L + +V+IGELD + Y D L+ EI ++ P + K PG + Sbjct: 1405 DRALTASLPRVVIGELDYEFMAEYAMDNAYIQLSQEIKNSLKPYIKMPQQVKQPGKRKIV 1464 Query: 1474 -PVPMEHRDYSGIESAIVKAWVKVLGLEQININDKFYDLGGDSISAIYLVKEIGKVFPSL 1532 P ++++Y+ +E + W +VLGLE+I+I + Y+LGGDSI A+ + EI K + Sbjct: 1465 LPKGRQNQEYTPMEKGVAAVWGEVLGLEEIDIYENLYNLGGDSIIALRIANEINKKLNAS 1524 Query: 1533 IDISDIFTYPSISEMSDYIQSLLEDRNGHAAGSVQPVTSEEE 1574 I ISD+F Y ++ ++ + LED+ SV+ + E+ Sbjct: 1525 IRISDLFEYLTVQRLA----AFLEDKTPEKEVSVKDLRESEK 1562 >B8I5I0.1 B8I5I0_CLOCE Condensation domain protein Length = 2006 Score = 998 bits (2579), Expect = 0.0, Method: Compositional matrix adjust. Identities = 587/1586 (37%), Positives = 902/1586 (56%), Gaps = 121/1586 (7%) Query: 23 SEDRLLRDSAVKPMSESDIAIIGMSGKFGEANDLRAFWEVLLKGKECIREIPLHRKADAD 82 +E+R+L+++ +S+ DIAIIGMSG+FG A +L +WE + GK+ I ++ R++D Sbjct: 17 AENRILKEN----ISKKDIAIIGMSGRFGAAENLSQYWEYIKDGKDLITDLSGTRQSDCM 72 Query: 83 RYL-EFSGGKSPHEDTQYTRIAYLDEIDKFDCGFFGILPNEAKLIDPRQRLFLESAWSTL 141 + +FS K +T+Y + A+ E+DKFD FF I P EA L+DP QRLFLE+ W + Sbjct: 73 HFASKFSNKKG---NTEYLKGAFFKELDKFDNDFFNISPREASLMDPNQRLFLENVWEAI 129 Query: 142 EDAGYGGGKLCGSKTGVYVGLSSDGXXXXEYFKLIEQGDPSLIGLSTAGNIKSVIAGRLA 201 EDAGY G ++ GSKTGVY+G S Y L+ + + SL S AGN+ S++A R+A Sbjct: 130 EDAGYCGKRIMGSKTGVYIGYSG---SKPTYETLLWESEASLAPESLAGNVNSMLASRIA 186 Query: 202 YILDFKGPSMMIDTACSSSLVALHVACQAIKNHECEAALVGGVNIKIFP-KTEEENNLNI 260 YILD KGP M++DTACSSSL+A+H+ACQAI+N EC A+ GG+ + P KT++ N + Sbjct: 187 YILDLKGPCMLVDTACSSSLMAVHLACQAIRNGECHIAVAGGIKTLLLPLKTDDSEN--V 244 Query: 261 GITSSDSSIRTFDDQADGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGSAVNQDGSSVG 320 GI SSD RTFDD +DGT GEGVAAVL+KPL++A+ D+DHIYAVIKGSA N DGSS+G Sbjct: 245 GIASSDGKARTFDDNSDGTGIGEGVAAVLLKPLEQALNDKDHIYAVIKGSAANNDGSSIG 304 Query: 321 ITAPNMTAQENVITDAWKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHRAFNRFTDRKQ 380 ITAPN AQ + I AW+++ I+P+T++Y EAHGTGTKLGDPIE+ I RAF ++TD+KQ Sbjct: 305 ITAPNSLAQRDAIVKAWEDSGINPETLSYIEAHGTGTKLGDPIEIDGIKRAFKKYTDKKQ 364 Query: 381 FCAIGSVKTNIGHLDSLAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQFSSSPVYVNDQ 440 FCAIGSVK+NIGHLD++AG+AGLIKAV+ IQY +IPP+LHFK PNR I F SPVYVND+ Sbjct: 365 FCAIGSVKSNIGHLDNVAGIAGLIKAVLCIQYGQIPPTLHFKRPNRKIMFEDSPVYVNDR 424 Query: 441 TTDWKGYDGVYRCGISSFGLSGTNAHVVLEGPPPLEQRQDEVPAN-HIFTVSAKTEASLE 499 +W+ RCGISSFG+SGTN H++LE P + + + + + T+SAK E SL Sbjct: 425 LHEWETMGYPRRCGISSFGISGTNCHMILEEAPNSKGKSENPQSKLQVLTLSAKNEKSLY 484 Query: 500 KLILNYLEFLGKEQELRISDLCYTVNTGRLPNQCRIAMIVSSTEELIRKLKLLARNGAGT 559 L+ ++ E+L K +E+ I D+C+T NTGR+ + RIA+I+ + ++ K+ LA Sbjct: 485 SLLKSFDEYLKKNKEVSIEDICFTQNTGRMHHSLRIALILENRHDMEEKISKLADLQPKG 544 Query: 560 YKAEDIY--YRKLERNLKFIGK------------SMTGSGGLTE---SSHKSIADLQLLC 602 + + +Y Y K+ RN + I S T S L E S + + L+ +C Sbjct: 545 IREQGVYYGYHKVVRNSEGIKNDGYISETDKRELSKTASERLKELVTSGNYNRGTLEEIC 604 Query: 603 GAYCDGADMDFEGIYRQLDCRKVSWPTYAFEQKRLWVELP-ESRRSLTAAR-TRHPLLQE 660 Y G D+D++ +Y+ + KVS PTY F +KR W++ + + S+ + R+ L Sbjct: 605 ILYTTGGDIDWDFLYKSEN--KVSLPTYPFNRKRFWIDTKRQMKESVQESHGERYKLPGY 662 Query: 661 RAVSSLNLEVYVSYLNVQDFWVLNEHQVNDACVIPGTAYLDMAKEIGTRHF-GEARDIIL 719 R ++N EVY + ++V++ W+L EH+V ++ GTAYL++A + +++ G+A +I Sbjct: 663 RISDTINQEVYTAEISVENQWLLREHKVGGNYMLVGTAYLELAMQTSKKYYPGKAVEI-- 720 Query: 720 SDVSFLNLLKVEKDEVKEIHTIVNIKDDALKFTVASRASAAEE-WIKHAEAWIGRKERQP 778 +++ L L V +++ E+HT++ + LKF +AS++ AE WI+HA+ I Sbjct: 721 RELTLLTPLIVGEEDKVELHTVIMKEYGFLKFVIASKSKTAENGWIEHAQGRI------- 773 Query: 779 HTTYDIETLKTTYDSVYAIRR-NQSWPVIEESSYTSVQYVEDTNRPESIINVGGRWKCTN 837 Y E L YD A++R W + + + +++ VG RW+C Sbjct: 774 ---YGTEKLSDKYDMTEALQRCTNEWDI-------------ENKQKNAVVEVGKRWQCLT 817 Query: 838 AIYRSKEGVLCELEIQAEYAEDLEQFYLHPAMMDCAVN-AGTFTINEDTYLPYYYKEFRI 896 + L LE+ EY D ++F LHP M+D A+N AG Y P+++ +I Sbjct: 818 KAFSGTNEALGYLELGEEYKGDFDEFQLHPPMLDTALNFAGDQAEKAGFYFPFHFNSVKI 877 Query: 897 FGPTPKKFYSYITKKNNENEETGKFDLLLLNEQGEVFGEISSYIVKRVHSFTPLEQPSAQ 956 P K S++ NN ++ T ++++ L++E V E+ Y+ K+ Q + Sbjct: 878 HNPISSKIISHVRILNN-SDRTIEYNITLVDENRRVLMEVDRYVTKKDAG-----QLLNK 931 Query: 957 KSIYHKLGWVEKNEY---KLLRRSEANGGILLFHNQAKLAGEIIASLRQAGKKVIEAIPG 1013 + H + WVE ++ K + N L F ++++ EII L G KVIE G Sbjct: 932 TDLLHSIEWVEYSDTAQDKAFDLLDGNKSTLFFSDKSRSCNEIINRLEAKGIKVIEVNTG 991 Query: 1014 QAFSERGEQAYSLGGRQEDYDKLFAAIELQKISQIIHLMTIQDHSAEGGH------QQLE 1067 + + G+ YS+G QED+ +LF+ ++ I+ I+ +S + G + LE Sbjct: 992 EEYGVLGKDKYSVGYSQEDFYQLFSQESIKDINYIV-------YSPDSGLPDTSDIKILE 1044 Query: 1068 YNLKLGLDSLFYLSQSIM-KHPNDPVELVLFAEHVHRISGSETAVNPHHAAFFGLGKVLG 1126 L+ + +LF L+++ M K+ +++V+ + +V+ ++G+E +NP +AA FG+ VL Sbjct: 1045 NKLENSVYNLFRLTKAWMQKNTGKDIKIVILSTYVNSVTGNEECLNPENAALFGMAFVLK 1104 Query: 1127 KEYSKLNVRCIDIDGETRAAECIREINGEKQVELVGYREGRPYVQELQAVPVPALPDQQA 1186 KEY L ++CID+D A I E + ++ +R GR Y+++L+ V P Sbjct: 1105 KEYPNLKIKCIDMDEGCEAESIISEFQTVHKTRMIAFRNGRRYIEQLKRVKREQNPSNSV 1164 Query: 1187 EIKKDGVYIITXXXXXXXXEVARYLSSLAKVNLILVGRSGLSH--------PIDPGSKNH 1238 +I+++GVYIIT E+A++++S +N+I++ RS + + K Sbjct: 1165 KIRENGVYIITGGLGGIGLEIAKHMASGTNLNVIMINRSEMPERSQWDTILETEKDLKLC 1224 Query: 1239 TRTEIMNHIRANGSNVDCYQADVADEREMQAMLAQLRQRYTSINGIFHCAGVAGEGFIFR 1298 + + + I + GS V Y DV+D + M+ ++ + + Y INGI H AG+AG G Sbjct: 1225 NKIKSIMDIESLGSKVTYYNGDVSDMQSMKLIIEDVIKNYGKINGIIHSAGIAGNGLAIT 1284 Query: 1299 KDKAAFDRVTRPKIQGTRILDKLTAEDKLDFFVMFSSITSLSGSMGQADYTAANAYLDSY 1358 KD+ V K++GT I+D LT+ +DF ++FSS +L+ S GQ+DYTAAN Y+D+Y Sbjct: 1285 KDEKRIKEVMAAKVKGTWIIDSLTSNLNMDFLLLFSSAETLTTSAGQSDYTAANYYMDTY 1344 Query: 1359 AEYRSLIKPEQKTLTINWCGWKDTGMLADYRNKLGKEAGTEENQNEQG-FKNIGTREAIE 1417 YR+ K Q T INW WK+TGM E N + G F + T + Sbjct: 1345 CYYRN--KRNQPTFCINWAAWKETGM------------AKEHNADRDGVFMVLSTANGVR 1390 Query: 1418 ALNVVLNKEISKVIIGELDDKVFGLYKDQITFSLAPEIAA---RIRPTRPK--APGHTGL 1472 + VL +VI G+L+ + K+ + +L PE++A R + TR G T Sbjct: 1391 VFDEVLKSGQPRVIAGQLNYNLLAGLKESLPVTLEPELSAVLDRSKKTRKSDIIAGTTKQ 1450 Query: 1473 PPVPME-----HRDYSGIESAIVKAWVKVLGLEQININDKFYDLGGDSISAIYLVKEIGK 1527 V ++ + E AI W + +IN+ D FYD GGDSI A+ + I Sbjct: 1451 DTVDIKLTGKTDDQITKTEQAIGYIWASIFQSNEINVYDSFYDQGGDSIFAMKITNVIRN 1510 Query: 1528 VFPSLIDISDIFTYPSISEMSDYIQS 1553 + I I+D+ SI E+ YI S Sbjct: 1511 TWGINISITDVMNNQSIYELGKYIDS 1536 >C3HA42.1 C3HA42_BACTU Beta-ketoacyl synthase Length = 1604 Score = 982 bits (2538), Expect = 0.0, Method: Compositional matrix adjust. Identities = 584/1644 (35%), Positives = 921/1644 (56%), Gaps = 122/1644 (7%) Query: 20 TLESEDRLLRDSAVKPMSESDIAIIGMSGKFGEANDLRAFWEVLLKGKEC--------IR 71 T E ++L++ + M DIA+IG+S K +AN+ +W L+ +C I+ Sbjct: 18 TQEQAKKMLQELNSESMQSEDIAVIGISCKLPKANNTEEYWNNLINSLDCKVNYQEEMIK 77 Query: 72 EI-PLHRKADADRYLEFSGGKSPHEDTQYTRIAYLDEIDKFDCGFFGILPNEAKLIDPRQ 130 I P+ +L SG + + + YL+++DKFD FF I P EAK IDP Sbjct: 78 YIKPIVNNKGFTDFLG-SGFLTEEQADDWKLGGYLEDVDKFDAEFFNISPKEAKAIDPSH 136 Query: 131 RLFLESAWSTLEDAGYGGGKLCGSKTGVYVGLSSDGXXXXEYFKLIEQGDPSLIGLSTAG 190 R+ LE+ W+ +EDAGYGG K+ GS T ++VG ++ I + + S S G Sbjct: 137 RVLLETVWTAIEDAGYGGDKIYGSNTSLFVG---KDHVNNTLYRYITESESS----SMTG 189 Query: 191 NIKSVIAGRLAYILDFKGPSMMIDTACSSSLVALHVACQAIKNHECEAALVGGVNIKIFP 250 N ++AGR+ Y+L+ KG SM++D+ACSS L+ +H+AC A+K+ ECE A+V G+++ FP Sbjct: 190 NWPGLMAGRINYLLNLKGNSMVLDSACSSGLLGVHLACNALKSKECEMAIVSGISLGFFP 249 Query: 251 KTEEENNLNIGITSSDSSIRTFDDQADGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGS 310 + E + S + FD ADGT +GVAAV++KPL+KA RD D+IYAVIKGS Sbjct: 250 RFETSRKS--MMESKSDKVNAFDKNADGTFFSDGVAAVILKPLNKARRDGDNIYAVIKGS 307 Query: 311 AVNQDGSSVGITAPNMTAQENVITDAWKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHR 370 A+N DG+S G+TAPN AQE V+ AW+ A+++P+T+ Y EAHGTGTKLGDPIE+ I Sbjct: 308 AINNDGASNGLTAPNAIAQEEVLIKAWENAQVNPETIQYIEAHGTGTKLGDPIEIKGITN 367 Query: 371 AFNRFTDRKQFCAIGSVKTNIGHLDSLAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQF 430 AF+++TD+ QFC +GSVK+NIGH +++GLA LIK V+++++ IPPS++FK PN I F Sbjct: 368 AFSKYTDKIQFCGVGSVKSNIGHTVAVSGLASLIKIVLSMKHNIIPPSINFKEPNSLINF 427 Query: 431 SSSPVYVNDQTTDWKGYDGVYRCGISSFGLSGTNAHVVLEGPPPLEQRQDEVPAN---HI 487 +SPV+V D+ W R GISSFG GTNAH+V+E P Q DE+ + + Sbjct: 428 VNSPVFVTDKPHKWPRGIVPRRAGISSFGFVGTNAHIVVEEPSI--QSNDELSSKLTFEV 485 Query: 488 FTVSAKTEASLEKLILNYLEFLGKEQELRISDLCYTVNTGRLPNQCRIAMIVSSTEELIR 547 FT+SAKTE SL +L+ Y EF K + + ++CYTVNTGR R+A+IV S EELI+ Sbjct: 486 FTLSAKTEKSLIQLLKKYNEFFKKGTQKSLKNICYTVNTGRGHYGYRLAIIVKSYEELIQ 545 Query: 548 KLKLLARNGAGTYKAEDIY--YRKLERNLKFIGKSMTGSGGLTESSHKS----------- 594 K+ LL + +Y Y K+ + K + G +T S H+ Sbjct: 546 KIDLLCNQNLNDISEKGVYFGYHKIGSD----RKKVMDEGEITLSEHRKMNTKVENLLLD 601 Query: 595 ---------IADLQLLCGAYCDGADMDFEGIYRQLDCRKVSWPTYAFEQKRLWVELPESR 645 + +L +C Y GA ++++ IY VS PTY FE+ + W E+ + R Sbjct: 602 ISNESNEYLVLNLTEICDLYIKGAKVNWKKIYVDEKRNIVSLPTYQFERIQCWGEVKDRR 661 Query: 646 RSLTAART-RHPLLQERAVSSLNLEVYVSYLNVQDFWVLNEHQVNDACVIPGTAYLDMAK 704 + HPL+ + S+N +Y + NV WVL++H++ VIPGT YL+M + Sbjct: 662 DETPIQKNISHPLIDQCLADSMNETIYSTTFNVDKDWVLSDHKIMGVSVIPGTTYLEMGR 721 Query: 705 EIGTRHFGEARDIILSDVSFLNLLKVEKDEVKEIHTIVNIKDDALKFTVASRASAAEEWI 764 + + FG ++ L DV F L V +DE K +HTI+ + + ++FT+AS+ E+WI Sbjct: 722 KASSEFFGN-NNLELRDVIFFTPLLVHQDENKVVHTIIKKEKEGVRFTIASK--EGEKWI 778 Query: 765 KHAEAWIGRKERQPHTTYDIETLKTTYDSVYAIRRNQSWPVIEESSYTSVQYVEDTNRPE 824 HAE GR Y+++ +K+ + ++++ + I+ V+Y +DT Sbjct: 779 PHAE---GR-------AYELKEMKSIMFDLSLMKKDANREKIK------VEYEDDTQLTS 822 Query: 825 SIINVGGRWKCTNAIYRSKEGVLCELEIQAEYAEDLEQFYLHPAMMDCAVNAGTFTINED 884 ++ G RW + + L EL++ E+ DL+ LHP+++D NA I ED Sbjct: 823 NVFTFGPRWLNFKEVILDHDEQLVELKLSDEFKGDLKDLLLHPSLLD---NAANVFIGED 879 Query: 885 ----TYLPYYYKEFRIFGPTPKKFYSYITKKNNENEETGKFDLLLLNEQGEVFGEISSYI 940 T+LP YK +I+ P+ FY+++ KK++ N+ET ++ L++ G VF EI+ Y+ Sbjct: 880 DDDSTFLPLSYKSVKIYSVMPQHFYAHVIKKSS-NKETKVCNIQLIDTAGVVFAEITDYV 938 Query: 941 VKRVHSFTPL--EQPSAQKSIYHKLGWVEKNEYKLLRRSEANGGILLFHNQAKLAGEIIA 998 +K+ + E + S YH + WV+ ++ + + + IL+F ++ ++ ++I Sbjct: 939 LKKADRLDTIFDENLEKESSFYH-IKWVQGSK-PVKVNTNTSETILVFKDKQEIYKKVIK 996 Query: 999 SLRQAGKKVIEAIPGQAFSERGEQAYSLGGRQEDYDKLFAAIELQKISQIIHLMTIQDHS 1058 L+ +I+ G F + +Q + + G +DY L ++ + I++IIHL ++ + Sbjct: 997 ELQYDNHNIIQVEFGNRFEKINDQQFIINGMADDYSNLINEVKERNITKIIHLSSMTNGE 1056 Query: 1059 A--EGGHQQLEYNLKLGLDSLFYLSQSI-MKHPNDPVELVLFAEHVHRISGSETAVNPHH 1115 A ++L++N GL SLFYL + I + ++L+L + +V ++G+E +NP Sbjct: 1057 AIHFSNLKELQHN---GLYSLFYLVRGISVNKVKRNIDLILISNNVTEVTGNEKTINPLG 1113 Query: 1116 AAFFGLGKVLGKEYSKLNVRCIDIDGETRAAECIREINGEKQVELVGYREGRPYVQELQA 1175 AA FGLG V+ +E+S + R ID+D T I EI E + + +R Y+ EL Sbjct: 1114 AAMFGLGSVISQEFSNIKCRAIDVDDHTAITSIIEEIKSEDKHYQIAFRNNIRYISELDV 1173 Query: 1176 VPVPALPDQQA---EIKKDGVYIITXXXXXXXXEVARYLSSLAKVNLILVGRSGLSHP-- 1230 V PD+Q EIK++GVY+IT E+A+YL+ KVN++L+ RS L Sbjct: 1174 VEHN--PDKQGAGLEIKENGVYMITGGTGGIGLEIAKYLAGKNKVNIVLLNRSKLPEMEL 1231 Query: 1231 ----IDPGS--KNHTRTEIMNHIRANGSNVDCYQADVADEREMQAMLAQLRQRYTSINGI 1284 I+ GS K + EI+ I+ GS V CY +V+D M ++ +++++Y INGI Sbjct: 1232 WEDIINDGSDQKLSRKLEIIRSIQGMGSEVKCYSCEVSDFSSMSKVIGEVKEKYGKINGI 1291 Query: 1285 FHCAGVAGEGFIFRKDKAAFDRVTRPKIQGTRILDKLTAEDKLDFFVMFSSITSLSGSMG 1344 FHCAGVAGEGFIFRK +A F V PKI GT ++D LT ++ +DF ++FSSI S+ G G Sbjct: 1292 FHCAGVAGEGFIFRKQEAVFKEVINPKISGTWLIDYLTKDENIDFSILFSSINSIFGGAG 1351 Query: 1345 QADYTAANAYLDSYAEYRSLIKPEQKTLTINWCGWKDTGMLADYRNKLGKEAGTEENQNE 1404 Q DYTAANAYLDS++ YR+ K +KT++INW W + G+ DY T+E Sbjct: 1352 QGDYTAANAYLDSFSYYRN--KKGKKTISINWPAWDEVGIAVDY-------GVTDE---F 1399 Query: 1405 QGFKNIGTREAIEALNVVLNKEISKVIIGELDDKVFGLYKDQITFSLAPEI------AAR 1458 FK + +A+ L+ +++ ++ VI G+L+ + + K ++ F L+ I A + Sbjct: 1400 SIFKLLTVNKALSILDTIVDNALTNVIPGKLNMDILEVAKGELPFELSISIKNKLKEAKK 1459 Query: 1459 IRPTRPKAPGHTGLPPVPMEHRD--YSGIESAIVKAWVKVLGLEQININDKFYDLGGDSI 1516 R K V ++ + YS E I + + VL + ++++ + F +GGDSI Sbjct: 1460 TRVETEKVSLKNSTSDVVIKGKGEYYSETEKNIAQMYSMVLDIPELDLYESFSAMGGDSI 1519 Query: 1517 SAIYLVKEIGKVFPSLIDISDIFTYPSISEMSDYIQSLLEDRNGHAAGSVQPVTSEEETE 1576 A L+K I + +P+L+DISDIFTYPS+ E+S+YI + + N H V ++ E Sbjct: 1520 MATQLLKLINQKYPNLVDISDIFTYPSVVELSEYIDGEI-NENDHLKNGETNVNNDNNLE 1578 Query: 1577 EDLDGILSKLASGELEVSEANQLL 1600 ++L + L G +++ + ++L Sbjct: 1579 KELRDLFDDLQKGNIDIQDGLEIL 1602 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.134 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 9,511,706,995 Number of extensions: 409377371 Number of successful extensions: 1055080 Number of sequences better than 1.0e-05: 9815 Number of HSP's gapped: 1020440 Number of HSP's successfully gapped: 14113 Length of query: 1606 Length of database: 3,060,696,203 Length adjustment: 150 Effective length of query: 1456 Effective length of database: 1,647,543,953 Effective search space: 2398823995568 Effective search space used: 2398823995568 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 138 (57.8 bits)