BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0382.0029.p (1606 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C3HA42.1 C3HA42_BACTU Beta-ketoacyl synthase 2234 0.0 B8I5H4.1 B8I5H4_CLOCE Beta-ketoacyl synthase 1117 0.0 B8I5H5.1 B8I5H5_CLOCE Amino acid adenylation domain protein 1063 0.0 B8I5I0.1 B8I5I0_CLOCE Condensation domain protein 1002 0.0 C3HA41.1 C3HA41_BACTU Beta-ketoacyl synthase 951 0.0 >C3HA42.1 C3HA42_BACTU Beta-ketoacyl synthase Length = 1604 Score = 2234 bits (5790), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1066/1611 (66%), Positives = 1305/1611 (81%), Gaps = 16/1611 (0%) Query: 1 MSVVQTYIFEQVKQHKLTQEEAKQMLRELKSEGAKKEDIAIIGISCRLPKASNTDEYWSN 60 MSV QTYI EQVKQ K+TQE+AK+ML+EL SE + EDIA+IGISC+LPKA+NT+EYW+N Sbjct: 1 MSVTQTYILEQVKQRKITQEQAKKMLQELNSESMQSEDIAVIGISCKLPKANNTEEYWNN 60 Query: 61 LMGGLDCKVEFQKEMIEHIKPIVNNKAYADFMGARFISEEEAEDCKMGGYLEDVDKFDAE 120 L+ LDCKV +Q+EMI++IKPIVNNK + DF+G+ F++EE+A+D K+GGYLEDVDKFDAE Sbjct: 61 LINSLDCKVNYQEEMIKYIKPIVNNKGFTDFLGSGFLTEEQADDWKLGGYLEDVDKFDAE 120 Query: 121 LFNISPKEAKAMDPSHRVLLETVWTAIEDAGYAGDKIYGSQTSLYVGKDHVNDTLYRYVT 180 FNISPKEAKA+DPSHRVLLETVWTAIEDAGY GDKIYGS TSL+VGKDHVN+TLYRY+T Sbjct: 121 FFNISPKEAKAIDPSHRVLLETVWTAIEDAGYGGDKIYGSNTSLFVGKDHVNNTLYRYIT 180 Query: 181 EDESTSMTGNWPGLMAGRINYLLNLKGNSMVLDSACSSGLLGVHLACNALKNKECEMAIV 240 E ES+SMTGNWPGLMAGRINYLLNLKGNSMVLDSACSSGLLGVHLACNALK+KECEMAIV Sbjct: 181 ESESSSMTGNWPGLMAGRINYLLNLKGNSMVLDSACSSGLLGVHLACNALKSKECEMAIV 240 Query: 241 SAISLGIFPRFSTARKSMMESQDDRVKTFDKNADGTFFSDGVAAVILKPLSKARQDGDNI 300 S ISLG FPRF T+RKSMMES+ D+V FDKNADGTFFSDGVAAVILKPL+KAR+DGDNI Sbjct: 241 SGISLGFFPRFETSRKSMMESKSDKVNAFDKNADGTFFSDGVAAVILKPLNKARRDGDNI 300 Query: 301 YAVIKGSAVNNDGASNGLTAPNAVAQEEVLLKAWEDAQIDPGTIQYIEAHGTGTKLGDPI 360 YAVIKGSA+NNDGASNGLTAPNA+AQEEVL+KAWE+AQ++P TIQYIEAHGTGTKLGDPI Sbjct: 301 YAVIKGSAINNDGASNGLTAPNAIAQEEVLIKAWENAQVNPETIQYIEAHGTGTKLGDPI 360 Query: 361 EIKGLTNAFAKHTDKAQFCGIGSVKANIGHTVAVSGLASLIKVVLSMKHNVIPSSIHFKE 420 EIKG+TNAF+K+TDK QFCG+GSVK+NIGHTVAVSGLASLIK+VLSMKHN+IP SI+FKE Sbjct: 361 EIKGITNAFSKYTDKIQFCGVGSVKSNIGHTVAVSGLASLIKIVLSMKHNIIPPSINFKE 420 Query: 421 PNSLINFIKSPVFVTEKPLQWPKSVLPRRAGINSFGFVGTNAHVVVEEAPDQAATSEAAG 480 PNSLINF+ SPVFVT+KP +WP+ ++PRRAGI+SFGFVGTNAH+VVEE Q+ ++ Sbjct: 421 PNSLINFVNSPVFVTDKPHKWPRGIVPRRAGISSFGFVGTNAHIVVEEPSIQSNDELSSK 480 Query: 481 PEYEIFTVSAKTEHSLRQLIHQYAEFFRQGTETNLSNICYTAKTGRGHYAYRLALIVKSY 540 +E+FT+SAKTE SL QL+ +Y EFF++GT+ +L NICYT TGRGHY YRLA+IVKSY Sbjct: 481 LTFEVFTLSAKTEKSLIQLLKKYNEFFKKGTQKSLKNICYTVNTGRGHYGYRLAIIVKSY 540 Query: 541 EELEQKISKLASNGLSDISGKGVYYDCHKIGSDRKQVRDQGEITLSEHRKLNSKAGSLLE 600 EEL QKI L + L+DIS KGVY+ HKIGSDRK+V D+GEITLSEHRK+N+K +LL Sbjct: 541 EELIQKIDLLCNQNLNDISEKGVYFGYHKIGSDRKKVMDEGEITLSEHRKMNTKVENLLL 600 Query: 601 EIVNDTSGYLILNLAEICNLYVKGAKVEWSLMYRDNKRRIVSLPTYQFDRVMYWGEVKDR 660 +I N+++ YL+LNL EIC+LY+KGAKV W +Y D KR IVSLPTYQF+R+ WGEVKDR Sbjct: 601 DISNESNEYLVLNLTEICDLYIKGAKVNWKKIYVDEKRNIVSLPTYQFERIQCWGEVKDR 660 Query: 661 RSELEVSVKNISHPLIDQCLADSMDETIYSTTFNVNTHWVLSDHKIMGVSVIPGTTYLEM 720 R E + KNISHPLIDQCLADSM+ETIYSTTFNV+ WVLSDHKIMGVSVIPGTTYLEM Sbjct: 661 RDETPIQ-KNISHPLIDQCLADSMNETIYSTTFNVDKDWVLSDHKIMGVSVIPGTTYLEM 719 Query: 721 GRKACSRLYHTDYLELRDVFFFTPLSVGQTEDKQVHTIVKKEKGYTRFIIASQEQGKWIT 780 GRKA S + + LELRDV FFTPL V Q E+K VHTI+KKEK RF IAS+E KWI Sbjct: 720 GRKASSEFFGNNNLELRDVIFFTPLLVHQDENKVVHTIIKKEKEGVRFTIASKEGEKWIP 779 Query: 781 HAEGKAYNPADESKDAERLIFDLAAARNDSRKETIKVKYE-DTSLSSKVFSFGPRWLNFK 839 HAEG+AY E K+ + ++FDL+ + D+ +E IKV+YE DT L+S VF+FGPRWLNFK Sbjct: 780 HAEGRAY----ELKEMKSIMFDLSLMKKDANREKIKVEYEDDTQLTSNVFTFGPRWLNFK 835 Query: 840 EVILDHNEQLVELELSEAFKGDLEELILHPSLLDNAANVFIGEDDDDSTFLPLSYKNIKI 899 EVILDH+EQLVEL+LS+ FKGDL++L+LHPSLLDNAANVFIGEDDDDSTFLPLSYK++KI Sbjct: 836 EVILDHDEQLVELKLSDEFKGDLKDLLLHPSLLDNAANVFIGEDDDDSTFLPLSYKSVKI 895 Query: 900 YSAMPQHFYAYVQKKSGNKETKTCDIQLIDMQGRIFVEIKDYVLKKVNHLLTLFKENDDL 959 YS MPQHFYA+V KKS NKETK C+IQLID G +F EI DYVLKK + L T+F EN + Sbjct: 896 YSVMPQHFYAHVIKKSSNKETKVCNIQLIDTAGVVFAEITDYVLKKADRLDTIFDENLEK 955 Query: 960 SGAFYRLNWVQAEPAAEGRRGHEGTVLVFKDTQGIYENIAGPLQNKAADTIQVEFGEAYK 1019 +FY + WVQ + T+LVFKD Q IY+ + LQ + IQVEFG ++ Sbjct: 956 ESSFYHIKWVQGSKPVKVNTNTSETILVFKDKQEIYKKVIKELQYDNHNIIQVEFGNRFE 1015 Query: 1020 RLTPNHYVIQGTENDYINLMNEIKDRNIRQILHLSSITGEAAATCADLADQQNRSLHSLF 1079 ++ ++I G +DY NL+NE+K+RNI +I+HLSS+T A ++L + Q+ L+SLF Sbjct: 1016 KINDQQFIINGMADDYSNLINEVKERNITKIIHLSSMTNGEAIHFSNLKELQHNGLYSLF 1075 Query: 1080 YLAKSISSNKIKENIDVVLISDNVTEVTGHEQEINPLGAALFGLGTVLTQEFKNIHCRAL 1139 YL + IS NK+K NID++LIS+NVTEVTG+E+ INPLGAA+FGLG+V++QEF NI CRA+ Sbjct: 1076 YLVRGISVNKVKRNIDLILISNNVTEVTGNEKTINPLGAAMFGLGSVISQEFSNIKCRAI 1135 Query: 1140 DVDRETPAELISEEIQRIESKYQVALRSGKRYTCELD--RHEPEHQEEQGLEIKEQGVYX 1197 DVD T I EEI+ + YQ+A R+ RY ELD H P+ Q GLEIKE GVY Sbjct: 1136 DVDDHTAITSIIEEIKSEDKHYQIAFRNNIRYISELDVVEHNPDKQ-GAGLEIKENGVYM 1194 Query: 1198 XXXXXXXXXLEIARYLAGKNAVHIALMNRSKLPEAASWDQLIQENPEHKLSRKLQAIKDI 1257 LEIA+YLAGKN V+I L+NRSKLPE W+ +I + + KLSRKL+ I+ I Sbjct: 1195 ITGGTGGIGLEIAKYLAGKNKVNIVLLNRSKLPEMELWEDIINDGSDQKLSRKLEIIRSI 1254 Query: 1258 RESGSEVSCYSCDIADPDQVNEVVQDLKGKYGRIHGIFHCAGVAGEGFTFRKPKAVFNEV 1317 + GSEV CYSC+++D +++V+ ++K KYG+I+GIFHCAGVAGEGF FRK +AVF EV Sbjct: 1255 QGMGSEVKCYSCEVSDFSSMSKVIGEVKEKYGKINGIFHCAGVAGEGFIFRKQEAVFKEV 1314 Query: 1318 VSPKVTGTWILDQATREENLEFFILFSSINAIFGGSGQGDYTAANAYLDSFSYSRNKRGA 1377 ++PK++GTW++D T++EN++F ILFSSIN+IFGG+GQGDYTAANAYLDSFSY RNK+G Sbjct: 1315 INPKISGTWLIDYLTKDENIDFSILFSSINSIFGGAGQGDYTAANAYLDSFSYYRNKKGK 1374 Query: 1378 RTISINWPAWSEVGIAADYGITEESSVFHMLTVKQALNFMDEMAAGGITHAIPGSLNRPL 1437 +TISINWPAW EVGIA DYG+T+E S+F +LTV +AL+ +D + +T+ IPG LN + Sbjct: 1375 KTISINWPAWDEVGIAVDYGVTDEFSIFKLLTVNKALSILDTIVDNALTNVIPGKLNMDI 1434 Query: 1438 LASVQDQLPFTLSGAIRSKLKGTGRTRTEPKETPEIEAAGDIVLKGKGTEYSETEKNIAQ 1497 L + +LPF LS +I++KLK +TR E ++ + D+V+KGKG YSETEKNIAQ Sbjct: 1435 LEVAKGELPFELSISIKNKLKEAKKTRVETEKVSLKNSTSDVVIKGKGEYYSETEKNIAQ 1494 Query: 1498 MYSLILDMHELDLYESFNAMGGDSIMATQLLKLIDKKYPDIVDISDIFTYSSVVELAEYI 1557 MYS++LD+ ELDLYESF+AMGGDSIMATQLLKLI++KYP++VDISDIFTY SVVEL+EYI Sbjct: 1495 MYSMVLDIPELDLYESFSAMGGDSIMATQLLKLINQKYPNLVDISDIFTYPSVVELSEYI 1554 Query: 1558 DRE----SHRSTPPAPVKAETVSEPVEQELRDLIENLKKGTIDVQDGLKML 1604 D E H V + +E+ELRDL ++L+KG ID+QDGL++L Sbjct: 1555 DGEINENDHLKNGETNVNNDN---NLEKELRDLFDDLQKGNIDIQDGLEIL 1602 >B8I5H4.1 B8I5H4_CLOCE Beta-ketoacyl synthase Length = 1613 Score = 1117 bits (2890), Expect = 0.0, Method: Compositional matrix adjust. Identities = 620/1641 (37%), Positives = 962/1641 (58%), Gaps = 69/1641 (4%) Query: 1 MSVVQTYIFEQVKQHKLTQEEAKQMLRELKSEGAKKE-DIAIIGISCRLPKASNTDEYWS 59 M+ V YI E ++++ A Q++R LK + + + DIAI+G++ +LP A N DE+W Sbjct: 1 MNRVFQYIVENTGNGNISKKAAAQIIRLLKDDEIRSDNDIAIVGMAAKLPFAPNIDEFWI 60 Query: 60 NLMGGLDCKVEFQKEMIEHIKPIVNNKAYADFMGARFISEEEAEDCKMGGYLEDVDKFDA 119 N+ G DC +F +E K +G + E E +G +L++VDKFD Sbjct: 61 NIRNGRDCVSDFPEE---------RKKDTDALLGHMNLKPSEIE-YSIGAFLDEVDKFDY 110 Query: 120 ELFNISPKEAKAMDPSHRVLLETVWTAIEDAGYAGDKIYGSQTSLYVG-KDHVNDTLYRY 178 + F +SPKEA +DP+ R+ L+T + AIED+GY ++ GS+T +YVG ++ R+ Sbjct: 111 KFFKLSPKEASLIDPNQRLFLQTAYQAIEDSGYGNGRLSGSKTGVYVGYSSDFGESYKRF 170 Query: 179 V-TEDESTS---MTGNWPGLMAGRINYLLNLKGNSMVLDSACSSGLLGVHLACNALKNKE 234 + T D S + GN ++A RI+Y L+LKG SM++D+ACSS L+ +H+AC A++N E Sbjct: 171 IHTVDPGLSGIAIPGNIKSIIASRISYYLDLKGPSMLVDTACSSSLVAIHMACRAIRNGE 230 Query: 235 CEMAIVSAISLGIFP-RFSTARKSMMESQDDRVKTFDKNADGTFFSDGVAAVILKPLSKA 293 CE A+ + L + P + + + S D + ++FD ++DGT +G AA++LKPL KA Sbjct: 231 CETALAGGVKLNLLPLKINRQDGIGITSSDGKARSFDDSSDGTGIGEGCAAILLKPLKKA 290 Query: 294 RQDGDNIYAVIKGSAVNNDGASNGLTAPNAVAQEEVLLKAWEDAQIDPGTIQYIEAHGTG 353 D DN+YAVIKGSA+N DG S G+TAPN+ AQEEV++KAW+DA ++P TI YIEAHGTG Sbjct: 291 IADRDNVYAVIKGSAINQDGNSIGITAPNSAAQEEVIVKAWKDAGVNPETISYIEAHGTG 350 Query: 354 TKLGDPIEIKGLTNAFAKHTDKAQFCGIGSVKANIGHTVAVSGLASLIKVVLSMKHNVIP 413 TKLGDP+EI G+ +AF ++TDK QFC +G+VK NIGH SG+A +IK+V+++ + +P Sbjct: 351 TKLGDPLEIDGIESAFKRYTDKKQFCALGTVKTNIGHLDNASGMAGVIKMVMALTNKELP 410 Query: 414 SSIHFKEPNSLINFIKSPVFVTEKPLQWPKSVLPRRAGINSFGFVGTNAHVVVEEAPD-- 471 +HFK PN N +SPV++ ++ QW PRR GI+SFG GTN H+++EEAP Sbjct: 411 PMLHFKRPNRKTNIQESPVYINDRLTQWETDGFPRRCGISSFGLSGTNCHMILEEAPSSE 470 Query: 472 --QAATSEAAGP-EYEIFTVSAKTEHSLRQLIHQYAEFFRQGTETNLSNICYTAKTGRGH 528 Q E+ P + T+SA +L+ I Y L +ICYTA TGR H Sbjct: 471 KPQYPAEESIIPYRKNVLTISANHVSALQSYIEAYRHMLDNIKNVTLEDICYTANTGRTH 530 Query: 529 YAYRLALIVKSYEELEQKISKLASNGLSDISGKGVYYDCHKIGSDRKQVRDQGEITLSEH 588 + R+A+I ++L+QK++ L + +I K +Y S ++ D I+ E+ Sbjct: 531 FPVRIAIITTDIKDLKQKLAFLTGSIKYNIDTKCIY-------SAKEYATDHPGISTFEN 583 Query: 589 RKLNSKAGSLLEEIVNDTSGYLILNLAEICNLYVKGAKVEWSLMYRDNKRRIVSLPTYQF 648 L +A +L ++ + + +L EIC Y+ G ++W +Y + VSLPTY F Sbjct: 584 --LTPEADTL-PDLTSASGDIYNKHLDEICKSYISGDHIQWDKVYDGKGMKKVSLPTYPF 640 Query: 649 DRVMYWGEVKDRRSE----LEVSVKNISHPLIDQCLADSMDETIYSTTFNVNTHWVLSDH 704 +R+ W ++ E S + +PL+D C ++M+ +YST F VN HWVL++H Sbjct: 641 ERLRCWLTANTPKAAEINAYEQSYNKLGYPLLDSCSTETMEGAVYSTNFQVNRHWVLNEH 700 Query: 705 KIMGVSVIPGTTYLEMGRKACSRLYHTDYLELRDVFFFTPLSVGQTEDKQVHTIVKKEKG 764 K+ G ++PGT+Y+EM +A + + LE RD+ F PL+VG+ E + V T++K E G Sbjct: 701 KVNGNFIVPGTSYIEMVSEAVGHYKYYENLEFRDIIFEFPLAVGENEARDVQTVLKIEDG 760 Query: 765 YTRFIIASQEQG-KWITHAEGKAYNPADESKDAERLIFDLAAARNDSRKETIKVKYEDTS 823 Y F +AS+ G KW+ H +GK + DE +++ + D AR+ +E I++ T Sbjct: 761 YLGFYVASRPDGDKWVRHVQGKVF--LDEDRNSVQYNPD-EMARSAIFEEDIEL----TG 813 Query: 824 LSSKVFSFGPRWLNFKEVILDHNEQLVELELSEAFKGDLEELILHPSLLDNAANVFIGED 883 + GPRW N K+V H+ L L L + F GDL++ I+HP+L+D+A NV IG Sbjct: 814 KRKGLIDTGPRWNNLKKVYTLHDGVLAYLVLPDEFTGDLDKCIIHPALMDSAVNVAIGSI 873 Query: 884 DDDSTFLPLSYKNIKIYSAMPQHFYAYVQKKSG---NKETKTCDIQLIDMQGRIFVEIKD 940 + +LP SYK++ IY MP Y+ +++K N ET + DI L+D +GR+F +I++ Sbjct: 874 GE-GLYLPWSYKSLIIYGKMPDKLYSLIRQKGKADLNMETASFDIILMDEKGRVFADIEN 932 Query: 941 YVLKKVNHLLTLFKENDDLSGAFYRLNWVQ------AEPAAEGRRGHEGTVLVFKDTQGI 994 Y LKKVN LLT F+R+NW++ E + G VL+FKD + Sbjct: 933 YTLKKVNQLLTTPDYKSVKVNMFHRMNWIKNYTTKGVESIHNAYKPAAGKVLLFKDRGSL 992 Query: 995 YENIAGPLQNKAADTIQVEFGEAYKRLTPNHYVIQGTENDYINLMNEIKDRNIRQILHLS 1054 + +I L D ++V+ Y++ Y I E DY L+ ++++ I QI+HLS Sbjct: 993 WMDIKETL---GVDVVEVDICGCYEKFATGRYSIGYGEEDYDRLIKDLREEGISQIIHLS 1049 Query: 1055 SITGEAAATCAD-LADQQNRSLHSLFYLAKSISSNKIKENIDVVLISDNVTEVTGHEQEI 1113 SI E +D LA+ Q R L+SL YL +S+ SNKI+ ++++ +SD V VTG E+ I Sbjct: 1050 SIGWEKLPEDSDSLAETQKRGLYSLVYLIRSLISNKIRNEVELIAVSDYVNMVTGMERRI 1109 Query: 1114 NPLGAALFGLGTVLTQEFKNIHCRALDVDRETPAELISEEIQRIESKYQVALRSGKRYTC 1173 N A + G+ TV QE+ N+ CR +D+D T + E+ +S +A R G+RY Sbjct: 1110 NYYNATIPGICTVAGQEYGNLKCRCIDIDETTEVNKLVSELNSRDSCSLIAYRDGERYHQ 1169 Query: 1174 ELDRHEPEHQEEQGLEIKEQGVYXXXXXXXXXXLEIARYLAGKNAVHIALMNRSKLPEAA 1233 E+D E E + +EI E+GVY E A YL+ K V + L+ R+ +P+ Sbjct: 1170 EMDEVHLEDSEPEEIEICEKGVYIITGGLGGIGREFAGYLSAKKPVSLVLIARTYIPDRE 1229 Query: 1234 SWDQLIQENPEHKLSRKLQAIKDIRESGSEVSCYSCDIADPDQVNEVVQDLKGKYGRIHG 1293 +WD+++++N L++K++ IKDI +SGS+V YS D+++ + + V+ ++ KYGRI+G Sbjct: 1230 AWDEILKKNSGTMLAQKIEFIKDIEKSGSQVVYYSADVSNENDMKNVLSSIRRKYGRING 1289 Query: 1294 IFHCAGVAGEGFTFRKPKAVFNEVVSPKVTGTWILDQATREENLEFFILFSSINAIFGGS 1353 + H AG+AG GF RK +F VV PKV GT+ILD+ T+E+NL+FFI+FSSIN+I GG+ Sbjct: 1290 VIHAAGIAGNGFIIRKDMEIFTRVVKPKVQGTFILDKLTKEDNLDFFIMFSSINSILGGA 1349 Query: 1354 GQGDYTAANAYLDSFS-YSRNKRGARTISINWPAWSEVGIAADYGITEES--SVFHMLTV 1410 GQ DYTAAN+++DSF+ Y R G +T+SINW AW E G+A D GI VF T Sbjct: 1350 GQSDYTAANSFMDSFADYRRKTAGGKTVSINWTAWKETGMAFDNGIINGKIRGVFLPATT 1409 Query: 1411 KQALNFMDEMAAGGITHAIPGSLNRPLLASVQDQLPFTLSGAIRSKL-KGTGRTRTEPKE 1469 A+ +E+ A +T I G L+ + + S I+ K+ K R+ T+ + Sbjct: 1410 SDAIQMFEEITAKKLTRIIAGQLDFETIPLLDSGTAIRFSNKIQGKIHKYKVRSNTDSQR 1469 Query: 1470 TPEIEAAGDIV-LKGKGTE---YSETEKNIAQMYSLILDMHELDLYESFNAMGGDSIMAT 1525 E G+I LK KG++ S + +A++++ L + E+ +Y++FN +GGDS+MAT Sbjct: 1470 NTARE--GEITPLKIKGSKDKGISSVQAVVARIWAGALGLEEVSVYDNFNDLGGDSVMAT 1527 Query: 1526 QLLKLIDKKYPDIVDISDIFTYSSVVELAEYID-RESHRSTPPAPVKAETVSEPVEQELR 1584 LLK ++K++P IVDISDIF Y S+ ++EYI+ R P + ++E E + Sbjct: 1528 LLLKNLEKEFPGIVDISDIFNYPSISAMSEYIESRTGKEKIQPDVENQQIMTEDGEAGME 1587 Query: 1585 DLIENLKKGTIDVQDGLKMLE 1605 ++++ L +G I +++ K+++ Sbjct: 1588 EIMQQLSRGEITIEEVDKLMK 1608 >B8I5H5.1 B8I5H5_CLOCE Amino acid adenylation domain protein Length = 3695 Score = 1063 bits (2750), Expect = 0.0, Method: Compositional matrix adjust. Identities = 588/1594 (36%), Positives = 936/1594 (58%), Gaps = 65/1594 (4%) Query: 26 LRELKSEGAKKEDIAIIGISCRLPKASNTDEYWSNLMGGLDCKVEFQKEMIEHIKPIVNN 85 L+ + E +D+AIIGIS + N DE++ +L G + +F + + I I+ Sbjct: 19 LKNISFEEVSTQDVAIIGISGKFASCGNMDEFYVSLRNGDNLVGKFPQRRKQDIDTILR- 77 Query: 86 KAYADFMGARFISEEEAEDCKMGGYLEDVDKFDAELFNISPKEAKAMDPSHRVLLETVWT 145 +MG ISE+E + G +L ++DKFD LFNISPKEA MDP+ R+ L+T W Sbjct: 78 -----YMG---ISEKETVYYE-GAFLNEIDKFDCSLFNISPKEAGLMDPNQRLFLQTAWN 128 Query: 146 AIEDAGYAGDKIYGSQTSLYVGK-DHVNDTLYRYVTEDEST----SMTGNWPGLMAGRIN 200 AIED+GY GD++ S+T +YVG N+ +YV + + S+TGN ++A RI+ Sbjct: 129 AIEDSGYGGDRLRSSRTGVYVGYCGDFNEDYRKYVQLMDPSMAALSVTGNIKSIVASRIS 188 Query: 201 YLLNLKGNSMVLDSACSSGLLGVHLACNALKNKECEMAIVSAISLGIFPRFSTARKSM-M 259 YLL+LKG SM++D+ACSS L+ +HLAC AL+ ECE AI + L + P + + + + Sbjct: 189 YLLDLKGPSMLVDTACSSTLVAIHLACQALRKGECETAIAGGVKLILLPVDNNPQNGIGI 248 Query: 260 ESQDDRVKTFDKNADGTFFSDGVAAVILKPLSKARQDGDNIYAVIKGSAVNNDGASNGLT 319 ES ++FD+ +DGT F +GVAA++LKPL KA +D DNIY++IKGSAVN DG S G+T Sbjct: 249 ESSSGVTRSFDEYSDGTGFGEGVAAIVLKPLKKAIEDRDNIYSIIKGSAVNQDGTSMGIT 308 Query: 320 APNAVAQEEVLLKAWEDAQIDPGTIQYIEAHGTGTKLGDPIEIKGLTNAFAKHTDKAQFC 379 PNA AQ +V+++AW+DA+IDP TI YIEAHGTGT LGDP+EI G+ AFA++T+K QFC Sbjct: 309 VPNAQAQSDVIIRAWKDAKIDPETISYIEAHGTGTNLGDPVEIDGIEMAFAQYTNKKQFC 368 Query: 380 GIGSVKANIGHTVAVSGLASLIKVVLSMKHNVIPSSIHFKEPNSLINFIKSPVFVTEKPL 439 + SVK NIGH + +G+A L+K VLS+KH + S+HF PN INF SPV++ + Sbjct: 369 AVSSVKTNIGHLDSAAGIAGLLKAVLSLKHKELFPSLHFDRPNQKINFQNSPVYINDSLE 428 Query: 440 QWPKSVLPRRAGINSFGFVGTNAHVVVEEAPD-QAATSEAAGPEYEIFTVSAKTEHSLRQ 498 QW PRR GI+SFG GTN H+V+EE P ++ E+ G Y IFT+S++ + L + Sbjct: 429 QWENHGGPRRCGISSFGLSGTNCHLVLEEPPQIKSIPEESPGCNYHIFTLSSQNINGLME 488 Query: 499 LIHQYAEFFRQGTETNLSNICYTAKTGRGHYAYRLALIVKSYEELEQKISKLASNGLSDI 558 + Y ++ + E +L ++C T TGRGHY +RLA ++ S EL++KI KL++ GL + Sbjct: 489 QLKNYEKYLNREREVSLGSLCSTTNTGRGHYNFRLAFVITSKNELKEKIQKLSTGGLENF 548 Query: 559 SGKGVYYDCHKIGSDRKQVRDQGEITLSEHRKLNSKAGSLLEEIVNDTSGYLILNLAEIC 618 GVY+ HKI K+ R E + E L+ + + L E +N+ S ++L IC Sbjct: 549 EKYGVYFGKHKIVDKEKESRGNNEYSQEEIADLSLQTETYLNEAINNESQQKKVSLENIC 608 Query: 619 NLYVKGAKVEWSLMYRDNKRRIVSLPTYQFDRVMYWGEVKDRRSELEVSVKNISHPLIDQ 678 LYV GA V+W+ +Y+ VSLP Y F + W E ++ S N HPLID+ Sbjct: 609 ALYVNGANVQWNRLYKSGSYAKVSLPGYSFMKKRCWIEHENSNSH------NSKHPLIDK 662 Query: 679 CLADSMDETIYSTTFNVNTHWVLSDHKIMGVSVIPGTTYLEMGRKACSRLYHTDYLELRD 738 + +S+D ++STTF V+ WVL++H+I V PGTTYLEM R+A + + L+++ Sbjct: 663 HILESVDLDVFSTTFKVDRQWVLNEHQIGSNYVAPGTTYLEMIREASRKHFGNHPLKMQQ 722 Query: 739 VFFFTPLSVGQTEDKQVHTIVKKEKGYTRFIIAS--QEQGKWITHAEGKAYNPADESKDA 796 V F PL + E+K+VHTI+K+++ + IAS +E G+W+ H+ G E DA Sbjct: 723 VTFIHPLILKADEEKEVHTIIKRDEDTLEYTIASKQKENGQWLKHSTGAVAGIPKE--DA 780 Query: 797 ERLIFDLAAARNDSRKETIKVKYEDTSLSSK--VFSFGPRWLNFKEVILDHNEQLVELEL 854 L FD + KE + ++ S+ + GPRW K + L EL Sbjct: 781 SSLSFDF-----EKIKEACPNVIDIGNMGSREGILRLGPRWDTLKAMYTGDRMALACFEL 835 Query: 855 SEAFKGDLEELILHPSLLD---NAANVFIGEDDDDSTFLPLSYKNIKIYSAMPQHFYAYV 911 E + DL + ++PSL+D N AN+ +GE +LPLSY ++KIY +P+ FY+Y+ Sbjct: 836 GEEYSEDLSKYHMYPSLMDCAVNIANMSVGE----GLYLPLSYGSLKIYETLPRSFYSYL 891 Query: 912 QKK---SGNKETKTCDIQLIDMQGRIFVEIKDYVLKKVNHLLTLFKENDDLSGAFYRLNW 968 +K S N E DI+L+D G+ EI+DY +KKV++ ++ D+L FY+ W Sbjct: 892 VRKDNMSLNNEIAIFDIKLMDEYGKALAEIEDYSVKKVHNTGLEAEDPDNL---FYKTGW 948 Query: 969 -VQAEPAAEGRRG-HEGTVLVFKDTQGIYENIAGPLQNKAADTIQVEFGEAYKRLTPNHY 1026 Q + G G ++F D G+ E +A L+ +T++VEFG ++++ + Y Sbjct: 949 EKQEQEFLTGENADFSGVTIIFNDEYGMGEELAQKLRAAGTETVEVEFGIDFRQINHSKY 1008 Query: 1027 VIQGTENDYINLMNEIKDRNIRQILHLSSITGEAAATCADLADQQNRSLHSLFYLAKSIS 1086 + E D+ L +E+ R + +I++LS++ + L + R +++L L K+IS Sbjct: 1009 MTGTDEGDFRKLFSELNGRAVNRIIYLSALNFDTDMDIDGLDEAMERGVYNLHRLTKAIS 1068 Query: 1087 SNKIKENIDVVLISDNVTEVTGHEQEINPLGAALFGLGTVLTQEFKNIHCRALDVDRETP 1146 + ++ ++D+V+I+DN +EV ++++IN L +L+ +G V+ QE+ NI CR +D+D+ Sbjct: 1069 ES-MQNDLDLVIIADNASEVVEYQEKINALSGSLYAMGRVIGQEYDNIRCRCIDIDKAVD 1127 Query: 1147 AELISEEIQRIESKYQVALRSGKRYTCELDRHEPEHQEEQGLEIKEQGVYXXXXXXXXXX 1206 +LI E+ + + + V+ R+G+RY L R P ++I+E+GVY Sbjct: 1128 TDLIISELAQKKFLFNVSYRNGQRYIQNLQRQSPYSNGGDKIQIREEGVYIVAGGLGGIG 1187 Query: 1207 LEIARYLAGKNAVHIALMNRSKLPEAASWDQLIQENPE------HKLSRKLQAIKDIRES 1260 LEI RYLA + V++ ++NRS LPE + WD L++ E + + ++Q+IK++++ Sbjct: 1188 LEICRYLAAEKRVNLVMINRSPLPERSLWDDLLKNTYEGINDTDYNIIDRIQSIKELKDM 1247 Query: 1261 GSEVSCYSCDIADPDQVNEVVQDLKGKYGRIHGIFHCAGVAGEGFTFRKPKAVFNEVVSP 1320 GS+V C+S D+AD V V+ +++ + I+G+ + AGV EG +K V++P Sbjct: 1248 GSKVLCFSADLADMASVRLVLDEVRKHHANINGVINLAGVFEEGILIKKDTEALKRVIAP 1307 Query: 1321 KVTGTWILDQATREENLEFFILFSSINAIFGGSGQGDYTAANAYLDSFSYSRNKRGARTI 1380 KV GT ILD+ T +NL+FF++FSSI + GG GQG+Y+AANA++DSF+ +N+ G + I Sbjct: 1308 KVNGTLILDRLTENDNLDFFVMFSSIASFIGGHGQGEYSAANAFMDSFAEYKNRTGRKVI 1367 Query: 1381 SINWPAWSEVGIAADYGITEESSVFHMLTVKQALNFMDEMAAGGITHAIPGSLNRPLLAS 1440 SINW W++VG+A+ Y +++ +F +++ ++A+ D + + G L+ +A Sbjct: 1368 SINWTGWNQVGMASQYNLSDGRRIFKLISKEKAIKAFDRALTASLPRVVIGELDYEFMAE 1427 Query: 1441 -VQDQLPFTLSGAIRSKLKGTGRTRTEPKETPEIEAAGDIVLKGK-GTEYSETEKNIAQM 1498 D LS I++ LK + P++ + ++ KG+ EY+ EK +A + Sbjct: 1428 YAMDNAYIQLSQEIKNSLKPYIKM---PQQVKQPGKRKIVLPKGRQNQEYTPMEKGVAAV 1484 Query: 1499 YSLILDMHELDLYESFNAMGGDSIMATQLLKLIDKKYPDIVDISDIFTYSSVVELAEYID 1558 + +L + E+D+YE+ +GGDSI+A ++ I+KK + ISD+F Y +V LA +++ Sbjct: 1485 WGEVLGLEEIDIYENLYNLGGDSIIALRIANEINKKLNASIRISDLFEYLTVQRLAAFLE 1544 Query: 1559 RESHRSTPPAPVKAETVSEPVEQELRDLIENLKK 1592 + TP V + + E ++ + N++K Sbjct: 1545 DK----TPEKEVSVKDLRESEKEHTYYELSNIQK 1574 Score = 61.6 bits (148), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 34/122 (27%), Positives = 70/122 (57%), Gaps = 11/122 (9%) Query: 1489 SETEKNIAQMYSLILDMHELDLYESFNAMGGDSIMATQLLKLIDKKYPDIVDISDIFTYS 1548 SE E+ +A ++S +LDM ++ ++F ++GG+S++ Q+ +ID+KYP + + DIF Y Sbjct: 3580 SEVERFLAGIWSQLLDMKKVGTKDNFFSLGGNSLLVNQMHSMIDEKYPGKIKVIDIFKYP 3639 Query: 1549 SVVELAEYIDRESHRSTPPAPVKAETVSEPVEQELRD----LIENLKKGTIDVQDGLKML 1604 ++ +LA++++ + K E V+ P + D L++ + G I + + L L Sbjct: 3640 TISKLADFMEGSEQK-------KYENVTVPTSDDGDDDIIKLLDGFESGDILIDEVLSKL 3692 Query: 1605 EN 1606 ++ Sbjct: 3693 DD 3694 >B8I5I0.1 B8I5I0_CLOCE Condensation domain protein Length = 2006 Score = 1002 bits (2591), Expect = 0.0, Method: Compositional matrix adjust. Identities = 556/1552 (35%), Positives = 877/1552 (56%), Gaps = 61/1552 (3%) Query: 32 EGAKKEDIAIIGISCRLPKASNTDEYWSNLMGGLDCKVEF----QKEMIEHIKPIVNNKA 87 E K+DIAIIG+S R A N +YW + G D + Q + + N K Sbjct: 24 ENISKKDIAIIGMSGRFGAAENLSQYWEYIKDGKDLITDLSGTRQSDCMHFASKFSNKKG 83 Query: 88 YADFMGARFISEEEAEDCKMGGYLEDVDKFDAELFNISPKEAKAMDPSHRVLLETVWTAI 147 +++ G + +++DKFD + FNISP+EA MDP+ R+ LE VW AI Sbjct: 84 NTEYLK--------------GAFFKELDKFDNDFFNISPREASLMDPNQRLFLENVWEAI 129 Query: 148 EDAGYAGDKIYGSQTSLYVGKDHVNDTLYRYVTEDEST----SMTGNWPGLMAGRINYLL 203 EDAGY G +I GS+T +Y+G T + E E++ S+ GN ++A RI Y+L Sbjct: 130 EDAGYCGKRIMGSKTGVYIGYSGSKPTYETLLWESEASLAPESLAGNVNSMLASRIAYIL 189 Query: 204 NLKGNSMVLDSACSSGLLGVHLACNALKNKECEMAIVSAISLGIFP-RFSTARKSMMESQ 262 +LKG M++D+ACSS L+ VHLAC A++N EC +A+ I + P + + + S Sbjct: 190 DLKGPCMLVDTACSSSLMAVHLACQAIRNGECHIAVAGGIKTLLLPLKTDDSENVGIASS 249 Query: 263 DDRVKTFDKNADGTFFSDGVAAVILKPLSKARQDGDNIYAVIKGSAVNNDGASNGLTAPN 322 D + +TFD N+DGT +GVAAV+LKPL +A D D+IYAVIKGSA NNDG+S G+TAPN Sbjct: 250 DGKARTFDDNSDGTGIGEGVAAVLLKPLEQALNDKDHIYAVIKGSAANNDGSSIGITAPN 309 Query: 323 AVAQEEVLLKAWEDAQIDPGTIQYIEAHGTGTKLGDPIEIKGLTNAFAKHTDKAQFCGIG 382 ++AQ + ++KAWED+ I+P T+ YIEAHGTGTKLGDPIEI G+ AF K+TDK QFC IG Sbjct: 310 SLAQRDAIVKAWEDSGINPETLSYIEAHGTGTKLGDPIEIDGIKRAFKKYTDKKQFCAIG 369 Query: 383 SVKANIGHTVAVSGLASLIKVVLSMKHNVIPSSIHFKEPNSLINFIKSPVFVTEKPLQWP 442 SVK+NIGH V+G+A LIK VL +++ IP ++HFK PN I F SPV+V ++ +W Sbjct: 370 SVKSNIGHLDNVAGIAGLIKAVLCIQYGQIPPTLHFKRPNRKIMFEDSPVYVNDRLHEWE 429 Query: 443 KSVLPRRAGINSFGFVGTNAHVVVEEAPDQAATSEAAGPEYEIFTVSAKTEHSLRQLIHQ 502 PRR GI+SFG GTN H+++EEAP+ SE + ++ T+SAK E SL L+ Sbjct: 430 TMGYPRRCGISSFGISGTNCHMILEEAPNSKGKSENPQSKLQVLTLSAKNEKSLYSLLKS 489 Query: 503 YAEFFRQGTETNLSNICYTAKTGRGHYAYRLALIVKSYEELEQKISKLASNGLSDISGKG 562 + E+ ++ E ++ +IC+T TGR H++ R+ALI+++ ++E+KISKLA I +G Sbjct: 490 FDEYLKKNKEVSIEDICFTQNTGRMHHSLRIALILENRHDMEEKISKLADLQPKGIREQG 549 Query: 563 VYYDCHKIGSDRKQVRDQGEITLSEHRKLNSKAGSLLEEIVNDTSG-YLILNLAEICNLY 621 VYY HK+ + + +++ G I+ ++ R+L+ A L+E+V TSG Y L EIC LY Sbjct: 550 VYYGYHKVVRNSEGIKNDGYISETDKRELSKTASERLKELV--TSGNYNRGTLEEICILY 607 Query: 622 VKGAKVEWSLMYRDNKRRIVSLPTYQFDRVMYWGEVKDRRSELEVSVKNISHPLIDQCLA 681 G ++W +Y+ + VSLPTY F+R +W + K + E + L ++ Sbjct: 608 TTGGDIDWDFLYKSENK--VSLPTYPFNRKRFWIDTKRQMKESVQESHGERYKLPGYRIS 665 Query: 682 DSMDETIYSTTFNVNTHWVLSDHKIMGVSVIPGTTYLEMGRKACSRLYHTDYLELRDVFF 741 D++++ +Y+ +V W+L +HK+ G ++ GT YLE+ + + Y +E+R++ Sbjct: 666 DTINQEVYTAEISVENQWLLREHKVGGNYMLVGTAYLELAMQTSKKYYPGKAVEIRELTL 725 Query: 742 FTPLSVGQTEDKQVHTIVKKEKGYTRFIIASQE---QGKWITHAEGKAYNPADESKDAER 798 TPL VG+ + ++HT++ KE G+ +F+IAS+ + WI HA+G+ Y S Sbjct: 726 LTPLIVGEEDKVELHTVIMKEYGFLKFVIASKSKTAENGWIEHAQGRIYGTEKLSDK--- 782 Query: 799 LIFDLAAARNDSRKE-TIKVKYEDTSLSSKVFSFGPRWLNFKEVILDHNEQLVELELSEA 857 +D+ A E I+ K ++ V G RW + NE L LEL E Sbjct: 783 --YDMTEALQRCTNEWDIENKQKNA-----VVEVGKRWQCLTKAFSGTNEALGYLELGEE 835 Query: 858 FKGDLEELILHPSLLDNAANVFIGEDDDDSTF-LPLSYKNIKIYSAMPQHFYAYVQKKSG 916 +KGD +E LHP +LD A N F G+ + + F P + ++KI++ + ++V+ + Sbjct: 836 YKGDFDEFQLHPPMLDTALN-FAGDQAEKAGFYFPFHFNSVKIHNPISSKIISHVRILNN 894 Query: 917 NKETKTCDIQLIDMQGRIFVEIKDYVLKK-VNHLLTLFKENDDLSGAFYRLNWVQAEPAA 975 + T +I L+D R+ +E+ YV KK LL + + + + WV+ A Sbjct: 895 SDRTIEYNITLVDENRRVLMEVDRYVTKKDAGQLL-------NKTDLLHSIEWVEYSDTA 947 Query: 976 EGRR-----GHEGTVLVFKDTQGIYENIAGPLQNKAADTIQVEFGEAYKRLTPNHYVIQG 1030 + + G++ T L F D I L+ K I+V GE Y L + Y + Sbjct: 948 QDKAFDLLDGNKST-LFFSDKSRSCNEIINRLEAKGIKVIEVNTGEEYGVLGKDKYSVGY 1006 Query: 1031 TENDYINLMNEIKDRNIRQILHLSSITGEAAATCADLADQQNRSLHSLFYLAKSISSNKI 1090 ++ D+ L ++ ++I I++ + L ++ S+++LF L K+ Sbjct: 1007 SQEDFYQLFSQESIKDINYIVYSPDSGLPDTSDIKILENKLENSVYNLFRLTKAWMQKNT 1066 Query: 1091 KENIDVVLISDNVTEVTGHEQEINPLGAALFGLGTVLTQEFKNIHCRALDVDRETPAELI 1150 ++I +V++S V VTG+E+ +NP AALFG+ VL +E+ N+ + +D+D AE I Sbjct: 1067 GKDIKIVILSTYVNSVTGNEECLNPENAALFGMAFVLKKEYPNLKIKCIDMDEGCEAESI 1126 Query: 1151 SEEIQRIESKYQVALRSGKRYTCELDRHEPEHQEEQGLEIKEQGVYXXXXXXXXXXLEIA 1210 E Q + +A R+G+RY +L R + E ++I+E GVY LEIA Sbjct: 1127 ISEFQTVHKTRMIAFRNGRRYIEQLKRVKREQNPSNSVKIRENGVYIITGGLGGIGLEIA 1186 Query: 1211 RYLAGKNAVHIALMNRSKLPEAASWDQLIQENPEHKLSRKLQAIKDIRESGSEVSCYSCD 1270 +++A +++ ++NRS++PE + WD +++ + KL K+++I DI GS+V+ Y+ D Sbjct: 1187 KHMASGTNLNVIMINRSEMPERSQWDTILETEKDLKLCNKIKSIMDIESLGSKVTYYNGD 1246 Query: 1271 IADPDQVNEVVQDLKGKYGRIHGIFHCAGVAGEGFTFRKPKAVFNEVVSPKVTGTWILDQ 1330 ++D + +++D+ YG+I+GI H AG+AG G K + EV++ KV GTWI+D Sbjct: 1247 VSDMQSMKLIIEDVIKNYGKINGIIHSAGIAGNGLAITKDEKRIKEVMAAKVKGTWIIDS 1306 Query: 1331 ATREENLEFFILFSSINAIFGGSGQGDYTAANAYLDSFSYSRNKRGARTISINWPAWSEV 1390 T N++F +LFSS + +GQ DYTAAN Y+D++ Y RNKR T INW AW E Sbjct: 1307 LTSNLNMDFLLLFSSAETLTTSAGQSDYTAANYYMDTYCYYRNKRNQPTFCINWAAWKET 1366 Query: 1391 GIAADYGITEESSVFHMLTVKQALNFMDEMAAGGITHAIPGSLNRPLLASVQDQLPFTLS 1450 G+A ++ + VF +L+ + DE+ G I G LN LLA +++ LP TL Sbjct: 1367 GMAKEHN-ADRDGVFMVLSTANGVRVFDEVLKSGQPRVIAGQLNYNLLAGLKESLPVTLE 1425 Query: 1451 GAIRSKLKGTGRTR-TEPKETPEIEAAGDIVLKGK-GTEYSETEKNIAQMYSLILDMHEL 1508 + + L + +TR ++ + DI L GK + ++TE+ I +++ I +E+ Sbjct: 1426 PELSAVLDRSKKTRKSDIIAGTTKQDTVDIKLTGKTDDQITKTEQAIGYIWASIFQSNEI 1485 Query: 1509 DLYESFNAMGGDSIMATQLLKLIDKKYPDIVDISDIFTYSSVVELAEYIDRE 1560 ++Y+SF GGDSI A ++ +I + + I+D+ S+ EL +YID E Sbjct: 1486 NVYDSFYDQGGDSIFAMKITNVIRNTWGINISITDVMNNQSIYELGKYIDSE 1537 >C3HA41.1 C3HA41_BACTU Beta-ketoacyl synthase Length = 1609 Score = 951 bits (2457), Expect = 0.0, Method: Compositional matrix adjust. Identities = 565/1599 (35%), Positives = 893/1599 (55%), Gaps = 68/1599 (4%) Query: 38 DIAIIGISCRLPKASNTDEYWSNLMGGLDCKVEFQKEMIEHIKPIVNNKAYADFMGARFI 97 DIAIIGIS + KA+N ++YW L+ ++E+I I PI K +++ I Sbjct: 41 DIAIIGISGKFGKANNLNDYWDLLIN--------EEELIRDI-PINRKKDADNYLEYSGI 91 Query: 98 SEEEAE-DCKMGGYLEDVDKFDAELFNISPKEAKAMDPSHRVLLETVWTAIEDAGYAGDK 156 + + + YL++++KFD + F I P EAK +DP R+ +ET W A+EDAGY G K Sbjct: 92 KNKNKDVNYTKIAYLDEINKFDCDFFEIIPNEAKLIDPRQRLFVETAWNALEDAGYGGGK 151 Query: 157 IYGSQTSLYVGKDHVNDTLYRYVTEDESTSM-----TGNWPGLMAGRINYLLNLKGNSMV 211 + G++T +YVG Y + E S+ GN ++A R+ Y+L+ KG +MV Sbjct: 152 LCGTKTGIYVGLSSDGSNEYFKLIEKGDQSLLGLATAGNIKSVIASRLAYILDFKGPTMV 211 Query: 212 LDSACSSGLLGVHLACNALKNKECEMAIVSAISLGIFPRFSTARKSMM--ESQDDRVKTF 269 +D+ACSS L+ +H AC AL+N++C+ A+V +++ +FP+ K + S D VKTF Sbjct: 212 IDTACSSSLVTLHTACQALRNRDCDTALVGGVNIKVFPKTEEENKWNIGITSSDSIVKTF 271 Query: 270 DKNADGTFFSDGVAAVILKPLSKARQDGDNIYAVIKGSAVNNDGASNGLTAPNAVAQEEV 329 D ADGT +GVAA++LKPL A D D IYAVIKGSA+N DG+S G+TAPN AQE V Sbjct: 272 DNEADGTNSGEGVAAILLKPLKNAILDKDQIYAVIKGSAINQDGSSVGITAPNVTAQENV 331 Query: 330 LLKAWEDAQIDPGTIQYIEAHGTGTKLGDPIEIKGLTNAFAKHTDKAQFCGIGSVKANIG 389 +L AW+DA IDP TI YIEAHGTGTKLGDPIE+ + AF+K TD+ QFC I SVK NIG Sbjct: 332 ILDAWKDAHIDPKTITYIEAHGTGTKLGDPIEVSAIQQAFSKFTDRKQFCAISSVKTNIG 391 Query: 390 HTVAVSGLASLIKVVLSMKHNVIPSSIHFKEPNSLINFIKSPVFVTEKPLQWPKSVLPRR 449 H +++GLA LIK V+++KH IP S++FK PN INF +SPV+V ++ W + R Sbjct: 392 HLDSLAGLAGLIKAVMALKHKKIPPSLNFKVPNRNINFHESPVYVNDRVQDWINNDGVYR 451 Query: 450 AGINSFGFVGTNAHVVVEEAPDQAATSEAAGPEYEIFTVSAKTEHSLRQLIHQYAEFFRQ 509 G++SFG GTN HV++EEAP E E IFTVSA+T+ SL L+++Y EF + Sbjct: 452 CGVSSFGLSGTNCHVILEEAPKIEQHEETVFSE-NIFTVSARTKKSLFNLLNRYVEFLGK 510 Query: 510 GTETNLSNICYTAKTGRGHYAYRLALIVKSYEELEQKISKLASNGLSDISGKGVYYDCHK 569 E L +ICYT TGR +RLALI+K+ EEL +K+ L + K +Y+ Sbjct: 511 EKEVKLHDICYTVNTGRLANKFRLALIIKTKEELLEKLELLVRSEWKTYPDKDIYF--QM 568 Query: 570 IGSDRKQVRDQGEITLSEHRKLNSKAGSLLEEIVNDTSGYLILNLAEICNLYVKGAKVEW 629 I + + + T + + ++ I D + +L + +Y GA V + Sbjct: 569 IEKNTRFIGRSIFFTRINESHTSHQIKRIINRIRKDITHINKCDLQFLSEVYCNGADVNF 628 Query: 630 SLMYRDNKRRIVSLPTYQFDRVMYWGEVKDRRSELEVSVKNISHPLIDQCLADSMDETIY 689 +YR + VSLPTY FD W ++K++ + +S + HPLI+ + S + +Y Sbjct: 629 EELYRQFNFQKVSLPTYSFDGKRLWIDLKEKSN--SISSEKDKHPLINNLVLQSFNMEVY 686 Query: 690 STTFNVNTHWVLSDHKIMGVSVIPGTTYLEMGRKACSRLYHTDY-LELRDVFFFTPLSVG 748 + NV HW+L++HK+ V+PGTTY++ R+ R + + + L++V F L V Sbjct: 687 VSHLNVKDHWILNEHKVENSYVVPGTTYIDTAREIGKRYFGDSWNIVLKNVMFPHLLQVK 746 Query: 749 QTEDKQVHTIVKKEKGYTRFIIASQ-EQGKWITHAEG----------KAYNPADESKDAE 797 E ++VHTI+ ++ F + S+ + +W+ HAE K Y+ K+ E Sbjct: 747 DVETREVHTIINIKEDALEFSVVSKLGEVEWVKHAEALIVKEVKERPKKYDIEVLKKNYE 806 Query: 798 RLIFDLAAARN--DSRKETIKVKY--EDTSLSSKVFSFGPRWLNFKEVILDHNEQLVELE 853 + R+ D ++ + Y EDT+ S + S G RW + + L ELE Sbjct: 807 SVYIIQKNNRSLVDVNQKDYESVYFIEDTNRSESIVSVGDRWKCTNAIYRNSEGVLCELE 866 Query: 854 LSEAFKGDLEELILHPSLLDNAANVFIGEDDDDSTFLPLSYKNIKIYSAMPQHFYAYVQK 913 + + ++ D + LHP+++D A N +D+S +LP YKN +I+ + P+ FY+Y+ K Sbjct: 867 IKKEYQNDFDCYSLHPAMMDCAVNAATFTINDES-YLPYYYKNFRIFGSTPKKFYSYITK 925 Query: 914 KSG-NKETKTCDIQLIDMQGRIFVEIKDYVLKKVNHLLTLFKENDDLSGAFYRLNWVQAE 972 K+ N+ET DI L++ G +F EI +Y++KKV H T ++ D +++L WV + Sbjct: 926 KTNDNEETGKFDILLLNEAGEVFGEISNYIVKKV-HGST--EKIDKSKQMYHKLAWVSKK 982 Query: 973 PAAEGRRGHEGTVLVFKDTQGIYENIAGPLQNKAADTIQVEFGEAYKRLTPNHYVIQGTE 1032 R+ +L+FK+ + IA L+ I+VE G+ + +++ Y I+G + Sbjct: 983 DYILERKYDNRNILLFKNEGELSNKIAKQLRVDGKSVIEVELGKQFSKISNWKYTIRGEQ 1042 Query: 1033 NDYINLMNEIKDRNIRQILHLSSITGEAAATCADLADQQNRSLHSLFYLAKSISSNKIKE 1092 DY L I++ NI QI+HL +I E L + + L SLFYL KSI N K Sbjct: 1043 EDYDKLFEAIENENINQIIHLMTINNETDEELLQLQKKLSIGLESLFYLTKSIMKN-TKN 1101 Query: 1093 NIDVVLISDNVTEVTGHEQEINPLGAALFGLGTVLTQEFKNIHCRALDVDRETPAELISE 1152 +++++L +D V G E +I P AA FG G V+ +E+ + R +D+D + E Sbjct: 1102 SMELLLFTDFAHRVNGEEFKIKPHNAAFFGFGKVIEKEYPKLSVRCIDIDDKICVEDCIT 1161 Query: 1153 EIQRIESKYQVALRSGKRYTCELDRHEPEHQEEQGLEIKEQGVYXXXXXXXXXXLEIARY 1212 EI + VA R +Y EL + + E+ +E K+ GVY LE+A+Y Sbjct: 1162 EINSKKQVELVAYRDKDKYVQELQNVDIKALPEEKVEFKKDGVYVITGGMGGIGLEMAKY 1221 Query: 1213 LAGKNAVHIALMNRSKLPEAASWDQLIQENPEHKLSRKLQAIKDIRESGSEVSCYSCDIA 1272 ++ K V++ L+ RS L AS + K++ K++ I +I+ESGS V CY ++A Sbjct: 1222 ISSKENVNLILIGRSGLSATAS--------EKSKIAYKIKTINEIQESGSRVECYKANVA 1273 Query: 1273 DPDQVNEVVQDLKGKYGRIHGIFHCAGVAGEGFTFRKPKAVFNEVVSPKVTGTWILDQAT 1332 + ++ EV ++++ K+ +I G+ H AGV+GEGF FRK K VF+ V+ PK+ GTWI++Q T Sbjct: 1274 NEHEIKEVFREIRKKFNKIDGVIHGAGVSGEGFIFRKEKEVFDNVIKPKIHGTWIMNQLT 1333 Query: 1333 REENLEFFILFSSINAIFGGSGQGDYTAANAYLDSFSYSRN--KRGARTISINWPAWSEV 1390 +++ L+FFI+FSSI ++ G GQ DY AANAY+DSF R+ +T++INW W++V Sbjct: 1334 KDDQLDFFIMFSSITSLGGSMGQADYAAANAYMDSFEEFRSLVVPEQKTLTINWCGWNDV 1393 Query: 1391 GIAADYGIT-----EESSVFHMLTVKQALNFMDEMAAGGITHAIPGSLNRPLLASVQDQL 1445 G+ A+Y ++++ F + +A+ DE+ I+ I G ++ +L + + Sbjct: 1394 GMLAEYIDKRKEEHKDNNGFKTINSIEAIYTFDEIIQKEISKVIIGEIDYKVLGVHKGLI 1453 Query: 1446 PFTLSGAIRSKLKGTGRTRTEPKETPEIEAAGDIVLKGKGTEYSETEKNIAQMYSLILDM 1505 F +S I L+ +T ++ K + E+ ++ +Y+ E I +++ +L + Sbjct: 1454 KFLISSDI---LQRIDQTVSKEKISEEMN-----FVRVNHIDYNSIENKILKVWIKVLGL 1505 Query: 1506 HELDLYESFNAMGGDSIMATQLLKLIDKKYPDIVDISDIFTYSSVVELAEYIDRESHRST 1565 ++ + + F +GGDSI A L+K I+K++P +D+SDIFTY S+ E+A YI+ E Sbjct: 1506 EQIGIDDKFYDLGGDSISAIYLMKEIEKEFPSRIDVSDIFTYPSIREMALYIESELKNDD 1565 Query: 1566 PPAPVKAETVSEPVEQELRDLIENLKKGTIDVQDGLKML 1604 P + E ++ ++ L G ++V + K++ Sbjct: 1566 DCVPSQIFE-DHHKEDDIDTILSKLASGELEVGEANKLI 1603 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.316 0.133 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 9,344,897,878 Number of extensions: 400646306 Number of successful extensions: 1143713 Number of sequences better than 1.0e-05: 9854 Number of HSP's gapped: 1108537 Number of HSP's successfully gapped: 14570 Length of query: 1606 Length of database: 3,060,696,203 Length adjustment: 150 Effective length of query: 1456 Effective length of database: 1,647,543,953 Effective search space: 2398823995568 Effective search space used: 2398823995568 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 138 (57.8 bits)