BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0382.0026.p (2232 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C3HA44.1 C3HA44_BACTU Hybrid nonribosomal peptide synthetase/pol... 2874 0.0 B9E2D3.1 B9E2D3_CLOK1 Putative uncharacterized protein 1380 0.0 A5N8Z4.1 A5N8Z4_CLOK5 Predicted hybrid nonribosomal peptide synt... 1380 0.0 C3H9Z8.1 C3H9Z8_BACTU Glutamate racemase 1145 0.0 C1FRI9.1 C1FRI9_CLOBJ Amino acid adenylation domain protein 1126 0.0 >C3HA44.1 C3HA44_BACTU Hybrid nonribosomal peptide synthetase/polyketide synthase Length = 2216 Score = 2874 bits (7451), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1381/2232 (61%), Positives = 1757/2232 (78%), Gaps = 18/2232 (0%) Query: 1 VDDTSIIKKYILEQIKAQSMDSEMALRMLKELTHKEKKDSNEIAIIGISCKFSNAGNTRE 60 +DD SII KYILEQ+K + MDSEMALR+LKEL++K +K + +IA+IGIS +F+ + N +E Sbjct: 1 MDDISIINKYILEQVKEKKMDSEMALRILKELSNKSQKSNRDIAVIGISGRFAESNNIKE 60 Query: 61 YWSNIVNSVGCIRDLPQVRKTDLDPLMNYAEMDAYFQAGFIEEIDKFDAAFFRISPREAM 120 YW+NI+N CIRDLPQ R+ D+DPL+N ++YF+AGF++EIDKFD+AFFRISPREAM Sbjct: 61 YWNNILNRTCCIRDLPQQRRIDIDPLLNNPNKNSYFKAGFLDEIDKFDSAFFRISPREAM 120 Query: 121 LMDPKQRLFLETVYHAIEDSGYAGRKIYGSDTGMYVGHDHSGDLKISYASLIKDSDMIAM 180 LMDPKQR+FLETVY AIEDSGYAG KIYGS+TG++VGHDHSGDLK SY SL+K++DMIAM Sbjct: 121 LMDPKQRMFLETVYQAIEDSGYAGNKIYGSNTGIFVGHDHSGDLKFSYDSLVKNADMIAM 180 Query: 181 TGTYPGILASRTSYIFNLKGPCLVVDTACSSGLVSVHLACNALKNEECSMAIAGGVNLFL 240 TGTYPGILASRTSYIFNLKGP LV+DTACSSGLVSVHLAC ALKN EC+MAIAGGVNLFL Sbjct: 181 TGTYPGILASRTSYIFNLKGPSLVIDTACSSGLVSVHLACEALKNGECNMAIAGGVNLFL 240 Query: 241 LPQQTGMMSEIEAGNGQISIFDKNAKGTMWGEGISALVLKPLNRAIEDGDHIYAVIKGSA 300 P+ G M+EIEA N ISIFDKNAKGT WGEGISA++LKPLN+AIED D+IYAVIKGSA Sbjct: 241 RPENIGTMNEIEAENAHISIFDKNAKGTAWGEGISAIILKPLNKAIEDRDNIYAVIKGSA 300 Query: 301 INNDGASNGITAPSAEAQGELIVRAWENAKIDPETIAYIETHGTGTILGDPIEIKGIANA 360 INNDGASNGITAP+A+AQ +LI RAWENAKI P+TI+YIETHGTGTILGDPIEIKGI NA Sbjct: 301 INNDGASNGITAPNADAQEKLISRAWENAKISPDTISYIETHGTGTILGDPIEIKGITNA 360 Query: 361 FKKYTARKQFCGIGSVKPNIGHTVAASGIASLIKTVMAIKEGIIPPSINFREPNPLINFS 420 FKKYT +KQFCGIGSVKPNIGHTV ASG+ASLIK VMA+KE ++PPSINF EPNPLINF+ Sbjct: 361 FKKYTDKKQFCGIGSVKPNIGHTVGASGMASLIKAVMALKEQVLPPSINFNEPNPLINFT 420 Query: 421 NSPVYVSDRARAWESGAEPKRAGVSSFGFSGTNCHIVLEEAPARAVNAESPHPVEILTLS 480 SPVYV+DR R W+ P+RAGVSSFGFSGTNCHIVLEEAP +E+ TLS Sbjct: 421 TSPVYVNDRIRKWKKNETPRRAGVSSFGFSGTNCHIVLEEAPIIDEKIGQEQVMEVFTLS 480 Query: 481 AKNKKSLQELIANYVQFLNEDGEFDLPGLCYTANTGRKHCEYRVCLKIKDKAELIREMNK 540 AKNK+SL LI Y+ F+ E+ + +L LCYTANTGRKH EYR+CL +KDK +L R++ K Sbjct: 481 AKNKESLYNLIEKYMDFIIEETDLNLSNLCYTANTGRKHWEYRICLMVKDKEDLKRKIEK 540 Query: 541 LNDNPIHLPNLKKLSHAEDRELKNSARQKVEAYNKSGRTETDILNEICSLYEKGGEVDWE 600 L + + N+ KLS+ E+R+LKN A QK+E Y +SG+ + +L+EIC LY++G ++DWE Sbjct: 541 LRNVSLDFQNVIKLSYMEERKLKNIANQKIEYYKQSGKKDMTVLHEICELYKRGIDIDWE 600 Query: 601 SLYEGEKRGKISIPVYPFLKERHWVNAPRRKTAEPDEEEQEGLWQNSLEAAAAGIQLEGR 660 SLYEGE+R KISIPVY FL+ERHWVN ++ P +++Q +N +E I L GR Sbjct: 601 SLYEGEERTKISIPVYAFLRERHWVNLHKKL---PVQQKQNINIENRVEK----ICLNGR 653 Query: 661 DSGRYSKAEISVGQVWGAVLGMNPMSVTADFYEIGGDSIIAIEIVNTLNTIMGLSLQVPV 720 +YS+ E+ VG+VWG LG+NP++VT+DFYE+GGDSIIAIEI+N +N M +++ V Sbjct: 654 KDYQYSEIEMMVGRVWGEALGINPINVTSDFYEMGGDSIIAIEIINRINKRMKINISVAD 713 Query: 721 LFEHSNIERLAAYIEGQ-AGTDKDTRGNSAIPRIAAAEHYEVSSSQKRIYILNQLNARST 779 LF++ NIE+ + YI+ + + AIP++ AE+YEVSS+QKRI+ILN+LN ST Sbjct: 714 LFKYPNIEKFSGYIKRHYKSSHTELNDYMAIPKVEEAEYYEVSSAQKRIFILNKLNHNST 773 Query: 780 SYNIPLFVMMEGPLDEGRLEHSFEALIQRHEVLRTSFSFVNKELVQAVDDHVHLAVEKYH 839 SYNIP F+M+EG LDE LE +F LI+RHEVLRTSF FV+ +L+Q ++++VH +E+Y Sbjct: 774 SYNIPFFLMIEGQLDEKHLELAFRKLIKRHEVLRTSFGFVDDKLIQVIEENVHFQLERYS 833 Query: 840 ADDETDLDQITSQFIRPFDLSKAPLIRAGLVEIRKNKHLLMLDVQHIIADGSSIPLLQKE 899 A ET+L+ + + F+RPF+L KAPLIR GLVE+ +KHLLM+DVQHIIADG+SIP+LQKE Sbjct: 834 A-RETELEHVINNFVRPFNLEKAPLIRGGLVEVSSDKHLLMIDVQHIIADGASIPILQKE 892 Query: 900 IIHLYEHNPLPELNIQFKDFAKWQNDLFKTDYMNKQKKYWLDVFSGELPILNLPVDYPRD 959 +I+LYE LP L IQFKDFAKWQN LF+T+ M KQK+YWL+ F GELPIL+LP D+ + Sbjct: 893 LIYLYEDQSLPRLKIQFKDFAKWQNRLFETNDMKKQKEYWLNEFKGELPILDLPGDFSKG 952 Query: 960 SGQGDQGERLTCNAGRELTQRLNEYSSKEKTTLFMTLLAAFNVLLFKHTGQEDIIVGSPI 1019 S Q DQG RL+ AG+ELT +LN+++ KEK TLFMTL+A+FNV LFKH+GQEDII+GSPI Sbjct: 953 SDQSDQGARLSFFAGKELTSKLNQFNLKEKVTLFMTLMASFNVFLFKHSGQEDIIIGSPI 1012 Query: 1020 AGRKHKELEQMIGMFVNTLALRNRPSAHMVFKEFLAGVKENALQAYEHQDYPFEELVDHL 1079 AGRKHKELE MIGMFVNT+ALRN PSA FKE L VK++AL+AYE+QDYPFEELV+ L Sbjct: 1013 AGRKHKELENMIGMFVNTIALRNHPSAEKTFKELLEQVKDSALKAYENQDYPFEELVNAL 1072 Query: 1080 NMDRNLSGTALFNVMFVLQVMDNPAFEVNGMHYAPYPYHNKTAKFDLALQVFPGLDELKF 1139 ++DR+L ALFNVMFVLQ+MDNP E+N + Y PY Y NKTAKFDL LQ FPG +++KF Sbjct: 1073 HIDRDLDRNALFNVMFVLQLMDNPTIEINKLKYTPYNYENKTAKFDLLLQAFPGQEDIKF 1132 Query: 1140 EFTYAAKLFKRSTIESFARRFLRVLEQVVALEHVLIGDIDVLDREELRDIRRYGQAGLPA 1199 EFTY++K+FKR+TIE F++RFL +LE +V+ E++LIGDI++LD E ++I + +P+ Sbjct: 1133 EFTYSSKIFKRNTIEKFSQRFLMILESIVSQENILIGDINILDENEKKEITSHSNILIPS 1192 Query: 1200 AYNTKTIVEMFEAQAARIPDHLAVSGFDRSLTYRELNEQANQLARVLIRNGACKDRVVGI 1259 N TI ++FE QA +P+H+AV G D +LTYRELN++ANQ+AR+LI+ G K+ VVGI Sbjct: 1193 NRNNGTICDIFEKQAELMPNHVAVMGLDGTLTYRELNKKANQIARLLIKKGIQKEDVVGI 1252 Query: 1260 IAERSTNFAVGIMGVLKSGAAYLPIEPAYPPERKRFMLEDSGACMVLTDTAHRRSLQHGI 1319 IA R+TNF GIMG++K+GAAYLP++ YP +R ++MLEDSGA M+LT++ R ++H I Sbjct: 1253 IANRNTNFVAGIMGIIKAGAAYLPLDINYPEKRIKYMLEDSGARMLLTESEKRNLVKHSI 1312 Query: 1320 REICLEEVAGNSGEQGNLEATASADSLAYVIYTSGSTGKPKGVMIEHRSVTNLAEALDEK 1379 E+ LE++ S + NL +SLAYVIYTSGSTG PKGVMIEH+S+ NL ALDE+ Sbjct: 1313 EELYLEDIDSESSD--NLSDRVVPESLAYVIYTSGSTGYPKGVMIEHKSIVNLVNALDER 1370 Query: 1380 IYSLHGPNLNVALLAPFVFDASVKQIFSAFLLGHHLNIVPGDVRQDVIQLAEYYKQNKID 1439 IY++HG NLNVALLAPF FDASVKQIFSA LLGH L+I+P D RQDV +LA YYK++KID Sbjct: 1371 IYNMHGSNLNVALLAPFAFDASVKQIFSALLLGHSLHIIPEDARQDVTKLAVYYKEHKID 1430 Query: 1440 ISDGTPAYLRLLAETSLCARIGVAHFIIGGEALSIAEVKRFYTSFANHKPPYITNVYGPT 1499 ISDGTPAY+ LL+ET LC+ IGV HFIIGGE L I E+K FY +F KPPYITNVYGPT Sbjct: 1431 ISDGTPAYISLLSETLLCSDIGVKHFIIGGETLLIEEIKNFYNNFKLTKPPYITNVYGPT 1490 Query: 1500 ECCVDATAFTIKPEETGQIQEMPIGAPIKNCSVYILDEQKRMVPRGVLGELYIGGHGVAR 1559 ECCVDAT + I PE+ I+E+ IG PIKNCS+YILDE+K++VP+G++GE+YIGG GV R Sbjct: 1491 ECCVDATTYMIDPEKIDFIKEISIGKPIKNCSIYILDEKKKLVPKGIIGEIYIGGEGVGR 1550 Query: 1560 GYCNNKALTSSRFVEDIYHPGMYMYKTGDMGKWTEDGLIHFAGRADHQVKIRGFRIELDE 1619 GY NN+ LT +F+ D+++P + MYKTGD+GKWTE+G I F GR+D QVKIRGFRIELDE Sbjct: 1551 GYRNNEELTDFKFIPDVFNPEVKMYKTGDLGKWTENGNIQFIGRSDRQVKIRGFRIELDE 1610 Query: 1620 IRHRLLSCDGVQAAVVLVQKDQRQEPYLCAYVVCRDEQVLPGLRGYLGEYLPDYMIPRVI 1679 I++R+LS GV+ AVV+V++D + AYVVC+DE +L L+ YL YLPDYMIP I Sbjct: 1611 IKNRILSFQGVKEAVVIVRQDS-----IYAYVVCKDEDLLFHLKEYLKRYLPDYMIPSGI 1665 Query: 1680 MPVDQIPMTANGKADTSQLPDPQEMRDHSLGYGAPRNRTEEILCTVWSEVLELRRIGIHD 1739 M +++IP+T NGK D S LP+ ++ + Y APRN EEI+ TVW+E+L + +IGI D Sbjct: 1666 MAIEEIPITNNGKVDISVLPNFEKSINDETQYIAPRNHIEEIISTVWAEILNIPKIGIRD 1725 Query: 1740 NFFAAGGDSIKAIQAAARMEKYNLRLEVKHLFQYQTIGEVSKKVQDRAGHAGYGAVTGEA 1799 NFF +GGDSIKAI+AA RMEKYN++LEVK +FQYQTI ++ K++DR VTGEA Sbjct: 1726 NFFVSGGDSIKAIKAANRMEKYNVKLEVKDIFQYQTIEGIASKIKDRNWVVDNSVVTGEA 1785 Query: 1800 GLVPIQSWMVEHCRDTLQHRNLSFVLYREAGFGEDNIRKVFTEIIRHHDALRMVFREQNR 1859 GLVPIQ+W++EH ++TL HRNLSF+LYR+ GFGE+NIRK+FT+II+HHDALR++F+++ Sbjct: 1786 GLVPIQNWLMEHHKETLNHRNLSFILYRKEGFGEENIRKIFTKIIQHHDALRIMFKDKGG 1845 Query: 1860 QMLQHNRGLDGELFDFYLIDLADSPSFSEEXXXXXXXXXXSMDLEKGPLVKLALIRAGYG 1919 +++Q NRGL+GELFDF++ID DS + + E SM+L KGPLVKLALI+A G Sbjct: 1846 EIVQINRGLEGELFDFHIIDAVDSSNINLE--VKVNQIQSSMELGKGPLVKLALIKAMDG 1903 Query: 1920 EHLLIVIHQMIIDHLSWRIILEDFNTAYTQLLNHEDIGLPPKTAPFLQWSNHLHEYADSI 1979 EHLLI+IHQMIIDH+SWRIILEDFN AYTQL N++DI LP KT FL+WS +L++YADS Sbjct: 1904 EHLLIIIHQMIIDHVSWRIILEDFNIAYTQLKNNKDIKLPNKTDSFLKWSKYLYKYADSE 1963 Query: 1980 ELLREQPYWDQVESIKAEPLPTDYKADEARVRDNLTLYQAFDCTETEQVMSSIRSNPHFT 2039 +LLRE+ YW +VESI P+PTD+ ++ RV+DN +Y+ F ET+ + I++N + Sbjct: 1964 KLLREKEYWSKVESIHMLPIPTDFDSNLNRVKDNQLIYRQFGQQETKNAIKIIKANRNLK 2023 Query: 2040 TESIMLTALALTIRAWTGNAAVVVNLGNHGRDMDSKDIDTYRTVGRFSILYPVALQLPES 2099 ESI LTAL LT++ W G +VVNLGNHGR+ +D+D +RTVGR S++YPVALQL E+ Sbjct: 2024 IESIFLTALGLTMKKWIGRDELVVNLGNHGRNYYGEDVDVFRTVGRLSVIYPVALQLVET 2083 Query: 2100 RNIDLCLEYVKEYLSGIPKQGGGYGVLKYLSSHQEGIRFRLNPELSFNYMGQFDAEFNTS 2159 NI L YV +YL IP +G G+G+LKYLSS++ + F L PE+SFNYMG+FD + NT Sbjct: 2084 ENIGSSLNYVNDYLDNIPNKGIGHGILKYLSSNKSEMTFTLKPEISFNYMGEFDTDINTE 2143 Query: 2160 TFRISPLSGGEDRSGEEIWSYKLKFISFIRMNQLNIGIEYNQQQYARETVNALLQQYMEY 2219 F +S L G+D S EE+W+YKLKFI+ +R N+LNI +EYNQ+QY R T+ LL QYME Sbjct: 2144 NFTVSSLPSGKDISNEEVWNYKLKFIALVRENKLNIRVEYNQKQYNRATIETLLDQYMEN 2203 Query: 2220 LKKAAEISEAIQ 2231 L K + E I Sbjct: 2204 LNKVIKDIEIIN 2215 >B9E2D3.1 B9E2D3_CLOK1 Putative uncharacterized protein Length = 2005 Score = 1380 bits (3572), Expect = 0.0, Method: Compositional matrix adjust. Identities = 744/1819 (40%), Positives = 1108/1819 (60%), Gaps = 69/1819 (3%) Query: 9 KYILEQIKAQSMDSEMALRMLKELTHKEKKDSNEIAIIGISCKFSNAGNTREYWSNIVNS 68 KYI+E +A +D ++A+ ++K L E +IAIIG+S A +YW+NI + Sbjct: 10 KYIIENERAGYLDRQIAVNLIKMLNTSETNSMKDIAIIGMSINMPMAQTLNDYWNNIRSG 69 Query: 69 VGCIRDLPQVRKTDLDPLMNYAEMDA----YFQAGFIEEIDKFDAAFFRISPREAMLMDP 124 C+ P RK D D + ++ M Y Q F+ +IDKFD FF++SP EA LMDP Sbjct: 70 KRCVIKFPNNRKMDTDQYLTWSGMSKNKQKYIQGAFLNDIDKFDYEFFKLSPNEARLMDP 129 Query: 125 KQRLFLETVYHAIEDSGYAGRKIYGSDTGMYVGHDHSGDLKISYASLIKDSD----MIAM 180 QRLFLET + AIED+GY K+ GS TG+YVG+ S DL+ +Y ++ + + +AM Sbjct: 130 GQRLFLETAWRAIEDAGYGIDKLSGSKTGIYVGY--STDLEYNYFRMVSEVEPSFTSMAM 187 Query: 181 TGTYPGILASRTSYIFNLKGPCLVVDTACSSGLVSVHLACNALKNEECSMAIAGGVNLFL 240 G P + R +YI NLKGP +VVDTACSS +V+VHLAC + N EC MAIAGG+ + L Sbjct: 188 LGNIPSFIPRRLAYILNLKGPSMVVDTACSSSMVAVHLACKGISNGECDMAIAGGIRINL 247 Query: 241 LPQQTGMMSEIEAGNGQISIFDKNAKGTMWGEGISALVLKPLNRAIEDGDHIYAVIKGSA 300 P Q + IE+ + + FD +A GT GEGI L+LKPL++A++D D IYAVIKGSA Sbjct: 248 FPLQNKVRIGIESPSFETRTFDNSADGTAMGEGIVGLLLKPLDKALDDRDSIYAVIKGSA 307 Query: 301 INNDGASNGITAPSAEAQGELIVRAWENAKIDPETIAYIETHGTGTILGDPIEIKGIANA 360 +N DG + GITAP+ ++Q ++IV AW+ +KI+PETI+YIE HGTGT LGD IEI+GI NA Sbjct: 308 VNQDGVTGGITAPNVDSQTQVIVDAWKASKINPETISYIEVHGTGTKLGDSIEIEGINNA 367 Query: 361 FKKYTARKQFCGIGSVKPNIGHTVAASGIASLIKTVMAIKEGIIPPSINFREPNPLINFS 420 F+K+T RKQFC + ++K N+GH ASGIA ++K ++++K +PP +NF PN INF Sbjct: 368 FEKFTNRKQFCAVSTLKTNMGHLYEASGIAGMVKAILSLKHKELPPLLNFTTPNYDINFE 427 Query: 421 NSPVYVSDRARAWESGAEPKRAGVSSFGFSGTNCHIVLEEA---PARAVNAESPHPVEIL 477 + +Y++DR R WE P+R GVSSF SGTNCH++LEEA P + + ES + V + Sbjct: 428 ETAIYINDRLREWEVEDYPRRCGVSSFAISGTNCHLILEEAPQLPKKVICRESKYKV--I 485 Query: 478 TLSAKNKKSLQELIANYVQFLNEDGEFDLPGLCYTANTGRKHCEYRVCLKIKDKAELIRE 537 TLSAK K+ L+ LI +Y++FLN D DL +C+TANTGR H +YR+ L I++ EL + Sbjct: 486 TLSAKKKEILKRLIVDYLKFLNMDESMDLDNICFTANTGRMHFDYRISLIIRNIDELKCK 545 Query: 538 MNKL-NDNPIHLP------------NLKKLSHAEDRELKNSARQKVEAYNKSGRTETDIL 584 +NKL D + N+ L+ E R++ A +K++ Y G+ E DIL Sbjct: 546 LNKLYKDKSLECTESDLSKGYFATDNVVNLTINEKRQMNFEANRKLKEYILGGKQEFDIL 605 Query: 585 NEICSLYEKGGEVDWESLYEGEKRGKISIPVYPFLKERHWVNAP-RRKTAEPDEEEQEGL 643 +E+C LY KG VDW LY E ++++P YPF +R W+ R+ A + + Sbjct: 606 SEVCKLYVKGANVDWNILYNNELHNRVNLPGYPFEDKRCWIKLDLNRERAGITKTNNKVD 665 Query: 644 WQNSLEAAAAGIQLEGRDSGRYSKAEISVGQVWGAVLGMNPMSVTADFYEIGGDSIIAIE 703 +N L + Q+ SG ++ + ++W +LG ++V DFY +GG+SIIA++ Sbjct: 666 VRNVLPCHSNKEQI--IISGDDFNLKLQIKKIWEEILGFEGINVNEDFYNLGGNSIIAMK 723 Query: 704 IVNTLNTIMGLSLQVPVLFEHSNIERLAAYIEGQAGTD--KDTRGNSAIPRIAAAEHYEV 761 I+N ++ + ++++V L +H I LA ++ D K+ S I +++ +++Y V Sbjct: 724 ILNVIHERLKINIKVSELLQHRTISDLALFLSEDFHKDNGKNVIPYSPIEKVSNSDYYPV 783 Query: 762 SSSQKRIYILNQLNARSTSYNIPLFVMMEGPLDEGRLEHSFEALIQRHEVLRTSFSFVNK 821 SS+QKR+ +++ L +YNI ++ + G +D RL ++F+ +I RHE+LRTSF FV+ Sbjct: 784 SSAQKRMLVIDHLQNSGIAYNICTYLEIHGMIDIDRLSNAFKEIISRHEILRTSFDFVDG 843 Query: 822 ELVQAVDDHVHLAVEKYHADDETDLDQITSQFIRPFDLSKAPLIRAGLVEIRKNKHLLML 881 +Q V + + ++ Y A E + ++ ++FIRPFDL K PL R G+++I ++KH L+L Sbjct: 844 IPIQRVSKRLSIDIQCYTA-KEHEFTKLMNRFIRPFDLKKLPLFRVGIIKISEDKHFLIL 902 Query: 882 DVQHIIADGSSIPLLQKEIIHLYEHNPLPELNIQFKDFAKWQNDLFKTDYMNKQKKYWLD 941 D+ HII DG+S+ +L E+ LY + LPEL IQ+KDFA WQN++ + + KQ+ YWL Sbjct: 903 DIHHIIFDGTSLGILMSELFSLYNGDNLPELKIQYKDFAAWQNNILQQPLLKKQESYWLK 962 Query: 942 VFSGELPILNLPVDYPRDSGQGDQGERLTCNAGRELTQRLNEYSSKEKTTLFMTLLAAFN 1001 VFSG++P+LNLP D PR S + +G+ L + L +++ + KTTL+M LA +N Sbjct: 963 VFSGQIPLLNLPTDNPRPSNRSFKGDCYRFELENTLVEALKQFTVQTKTTLYMVSLATYN 1022 Query: 1002 VLLFKHTGQEDIIVGSPIAGRKHKELEQMIGMFVNTLALRNRPSAHMVFKEFLAGVKENA 1061 LL+K TGQEDI+VG+P +GR HK+LE ++G+F+NTLA+R++ + F +FL V++N Sbjct: 1023 CLLWKLTGQEDIVVGTPTSGRIHKDLENLLGIFINTLAIRSKIEGNKKFIDFLKEVRKNV 1082 Query: 1062 LQAYEHQDYPFEELVDHLNMDRNLSGTALFNVMFVLQVMDNP---AFEVNGMHYAPYPYH 1118 L A EHQDY FE L++++++ R+LS LF+ MF+LQ DN F + + P+ +H Sbjct: 1083 LLALEHQDYQFENLIENIDIQRDLSRNPLFDTMFILQ--DNSYIKEFNTDELTIIPHVFH 1140 Query: 1119 NKTAKFDLALQVFPGLDELKFEFTYAAKLFKRSTIESFARRFLRVLEQVVALEHVLIGDI 1178 N + +D+ Q F ++ F Y LF+R TIE F++ F+ +L++V+ +V I DI Sbjct: 1141 NHLSVYDITFQAFEKDSDISFMIEYDCDLFERDTIEKFSKYFMNILKEVMRNPNVKIEDI 1200 Query: 1179 DVLDREELRDIRRYGQAGLPAAY-NTKTIVEMFEAQAARIPDHLAVSGFDRSLTYRELNE 1237 +VLD+ E R+ Y Y KTI E+FE Q AR P AV +++LTY++LNE Sbjct: 1201 EVLDKIE-REHLLYDFNNTALNYAKEKTIQELFEQQVARTPKDTAVVFKNQTLTYKQLNE 1259 Query: 1238 QANQLARVLIRNGACKDRVVGIIAERSTNFAVGIMGVLKSGAAYLPIEPAYPPERKRFML 1297 ++NQLAR+L NG D +VGI+ ERS +GI+GVLK+G AYLPI+P YP +R ++ML Sbjct: 1260 KSNQLARLLRNNGVGADNIVGIMVERSPEMLIGIIGVLKAGGAYLPIDPGYPVDRIQYML 1319 Query: 1298 EDSGACMVLTDTAHRRSLQHGIREICLEEVAGNSGEQ---GNLEATASADSLAYVIYTSG 1354 EDS ++LT + ++ I L + N+ + NL +A +LAYVIYTSG Sbjct: 1320 EDSKTNILLTQQSLLDKIEFKGEIIDL--FSSNAYAEMSITNLRILNNAQNLAYVIYTSG 1377 Query: 1355 STGKPKGVMIEHRSVTNLAEALDEKIYSLHGP-NLNVALLAPFVFDASVKQIFSAFLLGH 1413 STGKPKGVM+EH+SV N + I G LN+ ++ FD V + G Sbjct: 1378 STGKPKGVMLEHQSVNNFINGISNIINFTAGKIILNLTTIS---FDIFVLETLLPLCKGL 1434 Query: 1414 HLNIVPGDVRQDVIQLAEYYKQNKIDISDGTPAYLRLLAE--TSLCARIGVAHFIIGGEA 1471 + I + + D L +NK+D+ TP+ L+LL + L + +IGGEA Sbjct: 1435 KIIIADENEQIDAKLLNNLIIKNKVDMMQVTPSRLKLLMRGGSDLTCFKYLKDVMIGGEA 1494 Query: 1472 LS---IAEVKRFYTSFANHKPPYITNVYGPTECCVDATAFTIKPEETGQIQEMPIGAPIK 1528 L + ++K+ Y I N+YGPTE AT +++ E T I E+ IG PI Sbjct: 1495 LPDELLHQLKQVYYG-------KIFNMYGPTE----ATVWSMVKELT-DINEISIGKPIS 1542 Query: 1529 NCSVYILDEQKRMVPRGVLGELYIGGHGVARGYCNNKALTSSRFVEDIYHPGMYMYKTGD 1588 N +YI+D+ ++ P GV GEL IGG GVARGY N K LT +F + Y +Y+TGD Sbjct: 1543 NTQIYIIDKNNKLQPIGVSGELCIGGDGVARGYLNRKDLTKEKFFNNPYKVNEKIYRTGD 1602 Query: 1589 MGKWTEDGLIHFAGRADHQVKIRGFRIELDEIRHRLLSCDGVQAAVVLVQKDQRQEPYLC 1648 + KW DG + F GR D+QVKIRG+RIEL EI L +C G++ VV+ +++ + YL Sbjct: 1603 LAKWQPDGTVEFLGRIDNQVKIRGYRIELSEIEKSLGTCKGIKECVVISRENSTGDKYLI 1662 Query: 1649 AYVVCRDEQVLPGLRGYLGEYLPDYMIPRVIMPVDQIPMTANGKADTSQLPDPQEMRDH- 1707 AY V E + LR ++ + LPDYMIP +P+ +P+T NGK D LP+ R+ Sbjct: 1663 AYYVADMEIGVSKLREHMLKELPDYMIPSYFVPIKCMPLTPNGKIDKKALPEHDTGRNSL 1722 Query: 1708 SLGYGAPRNRTEEILCTVWSEVLELRRIGIHDNFFAAGGDSIKAIQAAARMEK-YNLRLE 1766 + Y AP + E+ L +W +VLE +GI+D FF GG+S+ +Q R++K Y ++E Sbjct: 1723 KIEYKAPTTQVEKQLVDIWEDVLEREEVGINDVFFELGGNSLLLVQMHTRIDKLYPGKVE 1782 Query: 1767 VKHLFQYQTIGEVSKKVQD 1785 V +F Y TI ++++ + + Sbjct: 1783 VADIFAYPTISKLAQFISE 1801 Score = 72.4 bits (176), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 114/529 (21%), Positives = 217/529 (41%), Gaps = 64/529 (12%) Query: 1725 VWSEVLELRRIGIHDNFFAAGGDSIKAIQAAARM-EKYNLRLEVKHLFQYQTIGEVSKKV 1783 +W E+L I ++++F+ GG+SI A++ + E+ + ++V L Q++TI +++ + Sbjct: 695 IWEEILGFEGINVNEDFYNLGGNSIIAMKILNVIHERLKINIKVSELLQHRTISDLALFL 754 Query: 1784 -QDRAGHAGYGAV-------TGEAGLVPIQS-----WMVEHCRDTLQHRNLSFVLYREAG 1830 +D G + + P+ S +++H +++ N+ L Sbjct: 755 SEDFHKDNGKNVIPYSPIEKVSNSDYYPVSSAQKRMLVIDHLQNSGIAYNICTYLEIHGM 814 Query: 1831 FGEDNIRKVFTEIIRHHDALRMVFREQNRQMLQH-NRGLDGELFDFYLIDLADSPSFSEE 1889 D + F EII H+ LR F + +Q ++ L ID+ + E Sbjct: 815 IDIDRLSNAFKEIISRHEILRTSFDFVDGIPIQRVSKRLS--------IDIQCYTAKEHE 866 Query: 1890 XXXXXXXXXXSMDLEKGPLVKLALIRAGYGEHLLIV-IHQMIIDHLSWRIILEDFNTAYT 1948 DL+K PL ++ +I+ +H LI+ IH +I D S I++ + + Y Sbjct: 867 FTKLMNRFIRPFDLKKLPLFRVGIIKISEDKHFLILDIHHIIFDGTSLGILMSELFSLY- 925 Query: 1949 QLLNHEDI-GLPPKTAPFLQWSNHLHEYADSIELLREQPYWDQVES--IKAEPLPTDYKA 2005 N +++ L + F W N++ + L +++ YW +V S I LPTD Sbjct: 926 ---NGDNLPELKIQYKDFAAWQNNILQQP---LLKKQESYWLKVFSGQIPLLNLPTDNPR 979 Query: 2006 DEARVRDNLTLYQAFDCTETEQVMSSIRSNPHFTTES----IMLTALALTIRAW--TGNA 2059 R DC E + + + FT ++ M++ W TG Sbjct: 980 PSNRSFKG-------DCYRFELENTLVEALKQFTVQTKTTLYMVSLATYNCLLWKLTGQE 1032 Query: 2060 AVVVNLGNHGRDMDSKDIDTYRTVGRFSILYPVALQLPESRN-IDLCLEYVKEYLSGIPK 2118 +VV GR KD++ +G F + ++ ++ ID E K L + Sbjct: 1033 DIVVGTPTSGRI--HKDLENL--LGIFINTLAIRSKIEGNKKFIDFLKEVRKNVLLALEH 1088 Query: 2119 QGGGY-GVLKYLSSHQEGIRFRLNPELSFNYMGQ---FDAEFNTSTFRISPLSGGEDRSG 2174 Q + +++ + ++ R NP ++ Q + EFNT I P S Sbjct: 1089 QDYQFENLIENIDIQRDLSR---NPLFDTMFILQDNSYIKEFNTDELTIIPHVFHNHLS- 1144 Query: 2175 EEIWSYKLKFISFIRMNQLNIGIEYNQQQYARETVNALLQQYMEYLKKA 2223 Y + F +F + + ++ IEY+ + R+T+ + +M LK+ Sbjct: 1145 ----VYDITFQAFEKDSDISFMIEYDCDLFERDTIEKFSKYFMNILKEV 1189 >A5N8Z4.1 A5N8Z4_CLOK5 Predicted hybrid nonribosomal peptide synthetase/polyketide synthase Length = 2001 Score = 1380 bits (3571), Expect = 0.0, Method: Compositional matrix adjust. Identities = 744/1819 (40%), Positives = 1108/1819 (60%), Gaps = 69/1819 (3%) Query: 9 KYILEQIKAQSMDSEMALRMLKELTHKEKKDSNEIAIIGISCKFSNAGNTREYWSNIVNS 68 KYI+E +A +D ++A+ ++K L E +IAIIG+S A +YW+NI + Sbjct: 6 KYIIENERAGYLDRQIAVNLIKMLNTSETNSMKDIAIIGMSINMPMAQTLNDYWNNIRSG 65 Query: 69 VGCIRDLPQVRKTDLDPLMNYAEMDA----YFQAGFIEEIDKFDAAFFRISPREAMLMDP 124 C+ P RK D D + ++ M Y Q F+ +IDKFD FF++SP EA LMDP Sbjct: 66 KRCVIKFPNNRKMDTDQYLTWSGMSKNKQKYIQGAFLNDIDKFDYEFFKLSPNEARLMDP 125 Query: 125 KQRLFLETVYHAIEDSGYAGRKIYGSDTGMYVGHDHSGDLKISYASLIKDSD----MIAM 180 QRLFLET + AIED+GY K+ GS TG+YVG+ S DL+ +Y ++ + + +AM Sbjct: 126 GQRLFLETAWRAIEDAGYGIDKLSGSKTGIYVGY--STDLEYNYFRMVSEVEPSFTSMAM 183 Query: 181 TGTYPGILASRTSYIFNLKGPCLVVDTACSSGLVSVHLACNALKNEECSMAIAGGVNLFL 240 G P + R +YI NLKGP +VVDTACSS +V+VHLAC + N EC MAIAGG+ + L Sbjct: 184 LGNIPSFIPRRLAYILNLKGPSMVVDTACSSSMVAVHLACKGISNGECDMAIAGGIRINL 243 Query: 241 LPQQTGMMSEIEAGNGQISIFDKNAKGTMWGEGISALVLKPLNRAIEDGDHIYAVIKGSA 300 P Q + IE+ + + FD +A GT GEGI L+LKPL++A++D D IYAVIKGSA Sbjct: 244 FPLQNKVRIGIESPSFETRTFDNSADGTAMGEGIVGLLLKPLDKALDDRDSIYAVIKGSA 303 Query: 301 INNDGASNGITAPSAEAQGELIVRAWENAKIDPETIAYIETHGTGTILGDPIEIKGIANA 360 +N DG + GITAP+ ++Q ++IV AW+ +KI+PETI+YIE HGTGT LGD IEI+GI NA Sbjct: 304 VNQDGVTGGITAPNVDSQTQVIVDAWKASKINPETISYIEVHGTGTKLGDSIEIEGINNA 363 Query: 361 FKKYTARKQFCGIGSVKPNIGHTVAASGIASLIKTVMAIKEGIIPPSINFREPNPLINFS 420 F+K+T RKQFC + ++K N+GH ASGIA ++K ++++K +PP +NF PN INF Sbjct: 364 FEKFTNRKQFCAVSTLKTNMGHLYEASGIAGMVKAILSLKHKELPPLLNFTTPNYDINFE 423 Query: 421 NSPVYVSDRARAWESGAEPKRAGVSSFGFSGTNCHIVLEEA---PARAVNAESPHPVEIL 477 + +Y++DR R WE P+R GVSSF SGTNCH++LEEA P + + ES + V + Sbjct: 424 ETAIYINDRLREWEVEDYPRRCGVSSFAISGTNCHLILEEAPQLPKKVICRESKYKV--I 481 Query: 478 TLSAKNKKSLQELIANYVQFLNEDGEFDLPGLCYTANTGRKHCEYRVCLKIKDKAELIRE 537 TLSAK K+ L+ LI +Y++FLN D DL +C+TANTGR H +YR+ L I++ EL + Sbjct: 482 TLSAKKKEILKRLIVDYLKFLNMDESMDLDNICFTANTGRMHFDYRISLIIRNIDELKCK 541 Query: 538 MNKL-NDNPIHLP------------NLKKLSHAEDRELKNSARQKVEAYNKSGRTETDIL 584 +NKL D + N+ L+ E R++ A +K++ Y G+ E DIL Sbjct: 542 LNKLYKDKSLECTESDLSKGYFATDNVVNLTINEKRQMNFEANRKLKEYILGGKQEFDIL 601 Query: 585 NEICSLYEKGGEVDWESLYEGEKRGKISIPVYPFLKERHWVNAP-RRKTAEPDEEEQEGL 643 +E+C LY KG VDW LY E ++++P YPF +R W+ R+ A + + Sbjct: 602 SEVCKLYVKGANVDWNILYNNELHNRVNLPGYPFEDKRCWIKLDLNRERAGITKTNNKVD 661 Query: 644 WQNSLEAAAAGIQLEGRDSGRYSKAEISVGQVWGAVLGMNPMSVTADFYEIGGDSIIAIE 703 +N L + Q+ SG ++ + ++W +LG ++V DFY +GG+SIIA++ Sbjct: 662 VRNVLPCHSNKEQI--IISGDDFNLKLQIKKIWEEILGFEGINVNEDFYNLGGNSIIAMK 719 Query: 704 IVNTLNTIMGLSLQVPVLFEHSNIERLAAYIEGQAGTD--KDTRGNSAIPRIAAAEHYEV 761 I+N ++ + ++++V L +H I LA ++ D K+ S I +++ +++Y V Sbjct: 720 ILNVIHERLKINIKVSELLQHRTISDLALFLSEDFHKDNGKNVIPYSPIEKVSNSDYYPV 779 Query: 762 SSSQKRIYILNQLNARSTSYNIPLFVMMEGPLDEGRLEHSFEALIQRHEVLRTSFSFVNK 821 SS+QKR+ +++ L +YNI ++ + G +D RL ++F+ +I RHE+LRTSF FV+ Sbjct: 780 SSAQKRMLVIDHLQNSGIAYNICTYLEIHGMIDIDRLSNAFKEIISRHEILRTSFDFVDG 839 Query: 822 ELVQAVDDHVHLAVEKYHADDETDLDQITSQFIRPFDLSKAPLIRAGLVEIRKNKHLLML 881 +Q V + + ++ Y A E + ++ ++FIRPFDL K PL R G+++I ++KH L+L Sbjct: 840 IPIQRVSKRLSIDIQCYTA-KEHEFTKLMNRFIRPFDLKKLPLFRVGIIKISEDKHFLIL 898 Query: 882 DVQHIIADGSSIPLLQKEIIHLYEHNPLPELNIQFKDFAKWQNDLFKTDYMNKQKKYWLD 941 D+ HII DG+S+ +L E+ LY + LPEL IQ+KDFA WQN++ + + KQ+ YWL Sbjct: 899 DIHHIIFDGTSLGILMSELFSLYNGDNLPELKIQYKDFAAWQNNILQQPLLKKQESYWLK 958 Query: 942 VFSGELPILNLPVDYPRDSGQGDQGERLTCNAGRELTQRLNEYSSKEKTTLFMTLLAAFN 1001 VFSG++P+LNLP D PR S + +G+ L + L +++ + KTTL+M LA +N Sbjct: 959 VFSGQIPLLNLPTDNPRPSNRSFKGDCYRFELENTLVEALKQFTVQTKTTLYMVSLATYN 1018 Query: 1002 VLLFKHTGQEDIIVGSPIAGRKHKELEQMIGMFVNTLALRNRPSAHMVFKEFLAGVKENA 1061 LL+K TGQEDI+VG+P +GR HK+LE ++G+F+NTLA+R++ + F +FL V++N Sbjct: 1019 CLLWKLTGQEDIVVGTPTSGRIHKDLENLLGIFINTLAIRSKIEGNKKFIDFLKEVRKNV 1078 Query: 1062 LQAYEHQDYPFEELVDHLNMDRNLSGTALFNVMFVLQVMDNP---AFEVNGMHYAPYPYH 1118 L A EHQDY FE L++++++ R+LS LF+ MF+LQ DN F + + P+ +H Sbjct: 1079 LLALEHQDYQFENLIENIDIQRDLSRNPLFDTMFILQ--DNSYIKEFNTDELTIIPHVFH 1136 Query: 1119 NKTAKFDLALQVFPGLDELKFEFTYAAKLFKRSTIESFARRFLRVLEQVVALEHVLIGDI 1178 N + +D+ Q F ++ F Y LF+R TIE F++ F+ +L++V+ +V I DI Sbjct: 1137 NHLSVYDITFQAFEKDSDISFMIEYDCDLFERDTIEKFSKYFMNILKEVMRNPNVKIEDI 1196 Query: 1179 DVLDREELRDIRRYGQAGLPAAY-NTKTIVEMFEAQAARIPDHLAVSGFDRSLTYRELNE 1237 +VLD+ E R+ Y Y KTI E+FE Q AR P AV +++LTY++LNE Sbjct: 1197 EVLDKIE-REHLLYDFNNTALNYAKEKTIQELFEQQVARTPKDTAVVFKNQTLTYKQLNE 1255 Query: 1238 QANQLARVLIRNGACKDRVVGIIAERSTNFAVGIMGVLKSGAAYLPIEPAYPPERKRFML 1297 ++NQLAR+L NG D +VGI+ ERS +GI+GVLK+G AYLPI+P YP +R ++ML Sbjct: 1256 KSNQLARLLRNNGVGADNIVGIMVERSPEMLIGIIGVLKAGGAYLPIDPGYPVDRIQYML 1315 Query: 1298 EDSGACMVLTDTAHRRSLQHGIREICLEEVAGNSGEQ---GNLEATASADSLAYVIYTSG 1354 EDS ++LT + ++ I L + N+ + NL +A +LAYVIYTSG Sbjct: 1316 EDSKTNILLTQQSLLDKIEFKGEIIDL--FSSNAYAEMSITNLRILNNAQNLAYVIYTSG 1373 Query: 1355 STGKPKGVMIEHRSVTNLAEALDEKIYSLHGP-NLNVALLAPFVFDASVKQIFSAFLLGH 1413 STGKPKGVM+EH+SV N + I G LN+ ++ FD V + G Sbjct: 1374 STGKPKGVMLEHQSVNNFINGISNIINFTAGKIILNLTTIS---FDIFVLETLLPLCKGL 1430 Query: 1414 HLNIVPGDVRQDVIQLAEYYKQNKIDISDGTPAYLRLLAE--TSLCARIGVAHFIIGGEA 1471 + I + + D L +NK+D+ TP+ L+LL + L + +IGGEA Sbjct: 1431 KIIIADENEQIDAKLLNNLIIKNKVDMMQVTPSRLKLLMRGGSDLTCFKYLKDVMIGGEA 1490 Query: 1472 LS---IAEVKRFYTSFANHKPPYITNVYGPTECCVDATAFTIKPEETGQIQEMPIGAPIK 1528 L + ++K+ Y I N+YGPTE AT +++ E T I E+ IG PI Sbjct: 1491 LPDELLHQLKQVYYG-------KIFNMYGPTE----ATVWSMVKELT-DINEISIGKPIS 1538 Query: 1529 NCSVYILDEQKRMVPRGVLGELYIGGHGVARGYCNNKALTSSRFVEDIYHPGMYMYKTGD 1588 N +YI+D+ ++ P GV GEL IGG GVARGY N K LT +F + Y +Y+TGD Sbjct: 1539 NTQIYIIDKNNKLQPIGVSGELCIGGDGVARGYLNRKDLTKEKFFNNPYKVNEKIYRTGD 1598 Query: 1589 MGKWTEDGLIHFAGRADHQVKIRGFRIELDEIRHRLLSCDGVQAAVVLVQKDQRQEPYLC 1648 + KW DG + F GR D+QVKIRG+RIEL EI L +C G++ VV+ +++ + YL Sbjct: 1599 LAKWQPDGTVEFLGRIDNQVKIRGYRIELSEIEKSLGTCKGIKECVVISRENSTGDKYLI 1658 Query: 1649 AYVVCRDEQVLPGLRGYLGEYLPDYMIPRVIMPVDQIPMTANGKADTSQLPDPQEMRDH- 1707 AY V E + LR ++ + LPDYMIP +P+ +P+T NGK D LP+ R+ Sbjct: 1659 AYYVADMEIGVSKLREHMLKELPDYMIPSYFVPIKCMPLTPNGKIDKKALPEHDTGRNSL 1718 Query: 1708 SLGYGAPRNRTEEILCTVWSEVLELRRIGIHDNFFAAGGDSIKAIQAAARMEK-YNLRLE 1766 + Y AP + E+ L +W +VLE +GI+D FF GG+S+ +Q R++K Y ++E Sbjct: 1719 KIEYKAPTTQVEKQLVDIWEDVLEREEVGINDVFFELGGNSLLLVQMHTRIDKLYPGKVE 1778 Query: 1767 VKHLFQYQTIGEVSKKVQD 1785 V +F Y TI ++++ + + Sbjct: 1779 VADIFAYPTISKLAQFISE 1797 Score = 72.4 bits (176), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 114/529 (21%), Positives = 217/529 (41%), Gaps = 64/529 (12%) Query: 1725 VWSEVLELRRIGIHDNFFAAGGDSIKAIQAAARM-EKYNLRLEVKHLFQYQTIGEVSKKV 1783 +W E+L I ++++F+ GG+SI A++ + E+ + ++V L Q++TI +++ + Sbjct: 691 IWEEILGFEGINVNEDFYNLGGNSIIAMKILNVIHERLKINIKVSELLQHRTISDLALFL 750 Query: 1784 -QDRAGHAGYGAV-------TGEAGLVPIQS-----WMVEHCRDTLQHRNLSFVLYREAG 1830 +D G + + P+ S +++H +++ N+ L Sbjct: 751 SEDFHKDNGKNVIPYSPIEKVSNSDYYPVSSAQKRMLVIDHLQNSGIAYNICTYLEIHGM 810 Query: 1831 FGEDNIRKVFTEIIRHHDALRMVFREQNRQMLQH-NRGLDGELFDFYLIDLADSPSFSEE 1889 D + F EII H+ LR F + +Q ++ L ID+ + E Sbjct: 811 IDIDRLSNAFKEIISRHEILRTSFDFVDGIPIQRVSKRLS--------IDIQCYTAKEHE 862 Query: 1890 XXXXXXXXXXSMDLEKGPLVKLALIRAGYGEHLLIV-IHQMIIDHLSWRIILEDFNTAYT 1948 DL+K PL ++ +I+ +H LI+ IH +I D S I++ + + Y Sbjct: 863 FTKLMNRFIRPFDLKKLPLFRVGIIKISEDKHFLILDIHHIIFDGTSLGILMSELFSLY- 921 Query: 1949 QLLNHEDIG-LPPKTAPFLQWSNHLHEYADSIELLREQPYWDQVES--IKAEPLPTDYKA 2005 N +++ L + F W N++ + L +++ YW +V S I LPTD Sbjct: 922 ---NGDNLPELKIQYKDFAAWQNNILQQP---LLKKQESYWLKVFSGQIPLLNLPTDNPR 975 Query: 2006 DEARVRDNLTLYQAFDCTETEQVMSSIRSNPHFTTES----IMLTALALTIRAW--TGNA 2059 R DC E + + + FT ++ M++ W TG Sbjct: 976 PSNRSFKG-------DCYRFELENTLVEALKQFTVQTKTTLYMVSLATYNCLLWKLTGQE 1028 Query: 2060 AVVVNLGNHGRDMDSKDIDTYRTVGRFSILYPVALQLPESRN-IDLCLEYVKEYLSGIPK 2118 +VV GR KD++ +G F + ++ ++ ID E K L + Sbjct: 1029 DIVVGTPTSGRI--HKDLENL--LGIFINTLAIRSKIEGNKKFIDFLKEVRKNVLLALEH 1084 Query: 2119 QGGGY-GVLKYLSSHQEGIRFRLNPELSFNYMGQ---FDAEFNTSTFRISPLSGGEDRSG 2174 Q + +++ + ++ R NP ++ Q + EFNT I P S Sbjct: 1085 QDYQFENLIENIDIQRDLSR---NPLFDTMFILQDNSYIKEFNTDELTIIPHVFHNHLS- 1140 Query: 2175 EEIWSYKLKFISFIRMNQLNIGIEYNQQQYARETVNALLQQYMEYLKKA 2223 Y + F +F + + ++ IEY+ + R+T+ + +M LK+ Sbjct: 1141 ----VYDITFQAFEKDSDISFMIEYDCDLFERDTIEKFSKYFMNILKEV 1185 >C3H9Z8.1 C3H9Z8_BACTU Glutamate racemase Length = 5273 Score = 1145 bits (2962), Expect = 0.0, Method: Compositional matrix adjust. Identities = 605/1553 (38%), Positives = 937/1553 (60%), Gaps = 19/1553 (1%) Query: 675 VWGAVLGMNPMSVTADFYEIGGDSIIAIEIVNTLNTIMGLSLQVPVLFEHSNIERLAAYI 734 +W +L + + + +F+EIGG S+ A +V+ ++ + + + + +F+ I+ + +I Sbjct: 2641 IWQDILDIENIGIQHNFFEIGGHSLKATTMVSRIHKELMVEIPLGQIFQVPTIKEIGEFI 2700 Query: 735 EGQAGTDKDTRGNSAIPRIAAAEHYEVSSSQKRIYILNQLNARSTSYNIPLFVMMEGPLD 794 + ++I ++ ++Y +SS+Q+R+YILN++ SYN+P + ++G LD Sbjct: 2701 NSTKES-----VYASIKKVEEQDYYPLSSAQRRLYILNKIEGSGVSYNMPFAMKIKGDLD 2755 Query: 795 EGRLEHSFEALIQRHEVLRTSFSFVNKELVQAVDDHVHLAVEKYHADDETDLDQITSQFI 854 +LE +F LI+RHE LRTSF V+ E VQ + ++ V Y LD I + F+ Sbjct: 2756 VHQLEQAFRKLIERHESLRTSFVMVDGEPVQKIKKDINSQV-TYREMGTNKLDDIINGFV 2814 Query: 855 RPFDLSKAPLIRAGLVEIRKNKHLLMLDVQHIIADGSSIPLLQKEIIHLYEHNPLPELNI 914 +PFDL KAPL+R ++ + ++H+++LD+ HII+DG S+ + +E+ LY L L+I Sbjct: 2815 KPFDLEKAPLLRVEIIHVTDDEHVMVLDMHHIISDGVSMGIFMQELAELYNGQKLSPLSI 2874 Query: 915 QFKDFAKWQNDLFKTDYMNKQKKYWLDVFSGELPILNLPVDYPRDSGQGDQGERLTCNAG 974 Q+KD+++WQ LF + + KQ+KYW++VF+ E+P+LN+P DY R + G+R+ Sbjct: 2875 QYKDYSEWQRGLFTQEEITKQEKYWMNVFNEEVPVLNMPTDYKRPKRRSFAGDRINLKIN 2934 Query: 975 RELTQRLNEYSSKEKTTLFMTLLAAFNVLLFKHTGQEDIIVGSPIAGRKHKELEQMIGMF 1034 E +LN+ +++ + T++M +LA + LL K++GQEDI+VGSPIAGRKH +L ++GMF Sbjct: 2935 SETYNQLNKLATENEVTMYMLMLAGYTTLLSKYSGQEDIVVGSPIAGRKHVDLNNVMGMF 2994 Query: 1035 VNTLALRNRPSAHMVFKEFLAGVKENALQAYEHQDYPFEELVDHLNMDRNLSGTALFNVM 1094 VNTLA+RN P + F+E+L VKEN L+AYE+QDY FEELV+ +N+ R++S LF+ M Sbjct: 2995 VNTLAMRNYPKGNRSFREYLKEVKENTLKAYENQDYQFEELVEKVNVRRDISRNPLFDTM 3054 Query: 1095 FVLQVMDNPAFEVNGMHYAPYPYHNKTAKFDLALQVFPGLDELKFEFTYAAKLFKRSTIE 1154 V Q DN ++G+ + + KFD+ + V L E Y L+K+ TIE Sbjct: 3055 LVFQHTDNMLLNLDGLKVSMLEDQREIVKFDITIHVSELEHGLGLEIEYCTALYKKETIE 3114 Query: 1155 SFARRFLRVLEQVVALEHVLIGDIDVL-DREELRDIRRYGQAGLPAAYNTKTIVEMFEAQ 1213 F F+ VL +VV + +ID+L ++E+ + + + A KT+ E+FE Q Sbjct: 3115 RFLEHFINVLREVVENPEQKLSEIDILTEKEKSKLLNEFNNTKGKYA-KEKTLPELFEEQ 3173 Query: 1214 AARIPDHLAVSGFDRSLTYRELNEQANQLARVLIRNGACKDRVVGIIAERSTNFAVGIMG 1273 + P+++A+ ++S+TY+ELNE+AN LA +L G D V GI+ ERS VGIMG Sbjct: 3174 VEKTPNNVALVFENQSITYKELNERANSLAHILREKGVGPDVVTGIMVERSIEMIVGIMG 3233 Query: 1274 VLKSGAAYLPIEPAYPPERKRFMLEDSG-ACMVLTDTAHRRSLQHGIREICLEEVAGNSG 1332 +LK+G AYLPI+P YP RK +ML +S + +T+ H G + I L+++ Sbjct: 3234 ILKAGGAYLPIDPTYPRTRKEYMLRNSHIEILCVTNEVHSDISFRG-QIIQLDKLKYKEN 3292 Query: 1333 EQGNLEATASADSLAYVIYTSGSTGKPKGVMIEHRSVTNLAEALDEKIYSLHGPNLNVAL 1392 + N+ S +LAYVIYTSGSTG PKGVMIE SV NL L+ IY N+NVAL Sbjct: 3293 -RTNISKINSPRNLAYVIYTSGSTGNPKGVMIEQNSVNNLVNGLNNVIYKRFNTNVNVAL 3351 Query: 1393 LAPFVFDASVKQIFSAFLLGHHLNIVPGDVRQDVIQLAEYYKQNKIDISDGTPAYLRLLA 1452 LAPF+FDASVKQIF+ LLGH L +VP +V + + L EYY NKI +SD TPA+L +L+ Sbjct: 3352 LAPFIFDASVKQIFATLLLGHTLFVVPKEVCWNAMSLIEYYATNKIHVSDATPAHLTMLS 3411 Query: 1453 ETS-LCARIGVAHFIIGGEALSIAEVKRFYTSFANHKPPYITNVYGPTECCVDATAFTIK 1511 + + + + FI+GGEAL+ +K + FA+ KP ITNVYGPTECCVD+T++ I+ Sbjct: 3412 YVNKIEQELEIKEFIVGGEALTPYLIKGLFGKFADFKPN-ITNVYGPTECCVDSTSYRIE 3470 Query: 1512 PEETGQIQEMPIGAPIKNCSVYILDEQKRMVPRGVLGELYIGGHGVARGYCNNKALTSSR 1571 ++ + +PIG PI N ++YILD+ + P GV GEL + G G+ARGY NN LT+ R Sbjct: 3471 FDQISGDKVIPIGKPILNTNIYILDKGNNLQPIGVAGELCVSGEGIARGYLNNLELTAER 3530 Query: 1572 FVEDIYHPGMYMYKTGDMGKWTEDGLIHFAGRADHQVKIRGFRIELDEIRHRLLSCDGVQ 1631 F+E+ ++ G MY+TGD+ +W DG I F GR DHQVKIRG+RIEL EI +L + ++ Sbjct: 3531 FIENPFNNGKSMYRTGDLARWLPDGNIEFLGRIDHQVKIRGYRIELGEIESQLSTHQDIE 3590 Query: 1632 AAVVLVQKDQRQEPYLCAYVVCRDEQVLPGLRGYLGEYLPDYMIPRVIMPVDQIPMTANG 1691 +V+ ++D+ YLCAY+V + E +R YL + LPDYMIP + +D++P+T NG Sbjct: 3591 ETIVIAREDKESNQYLCAYIVSQKELHAREIREYLEQKLPDYMIPGFFVKLDKLPLTTNG 3650 Query: 1692 KADTSQLPDPQEMRDHSLGYGAPRNRTEEILCTVWSEVLELRRIGIHDNFFAAGGDSIKA 1751 K D LP+P + + Y PRN EE L +W ++ + IGI+ NFF +GGDSIKA Sbjct: 3651 KVDRKALPEPDGSINTGVEYEEPRNEVEEKLFEIWRSIIGIEDIGINHNFFVSGGDSIKA 3710 Query: 1752 IQAAARMEKYNLRLEVKHLFQYQTIGEVSKKVQ-DRAGHAGYGAVTGEAGLVPIQSWMVE 1810 IQ +R+ + L+LE+K LF I + K ++ ++ + V GE L PIQSW E Sbjct: 3711 IQIISRLSRIGLKLEMKDLFANPKIKNLGKYIKREKKEQKVHEIVNGEVELTPIQSWYFE 3770 Query: 1811 HCRDTLQHRNLSFVLYREAGFGEDNIRKVFTEIIRHHDALRMVFREQNRQMLQHNRGLDG 1870 ++ + H N SF+L+RE GF E I +VF +I+ HHDALRM+++E+ +++Q+NRG D Sbjct: 3771 KNQEEIHHFNQSFMLFRENGFDEKQIEEVFNKIMEHHDALRMIYKEKEGEIIQYNRGYDK 3830 Query: 1871 ELFDFYLIDLADSPSFSEEXXXXXXXXXXSMDLEKGPLVKLALIRAGYGEHLLIVIHQMI 1930 LFD Y+ D+ + E+ MD+++G LVKL + ++ G+HLLI IH ++ Sbjct: 3831 NLFDLYIHDVKGVENKEEKVYEIATNIQKEMDIKEGKLVKLCIFKSDEGDHLLIAIHHLV 3890 Query: 1931 IDHLSWRIILEDFNTAYTQLLNHEDIGLPPKTAPFLQWSNHLHEYADSIELLREQPYWDQ 1990 +D +SWRI+LED T Y+QL E + + KT + ++++ L Y+ S EL++E+ YW Sbjct: 3891 VDGVSWRILLEDLETLYSQLEKGEKLEIGFKTDSYKEFASKLKAYSVSRELMKEREYWTS 3950 Query: 1991 VESIKAEPLPTDYKADEARVRDNLTLYQAFDCTETEQVMSSIRSNPHFTTE--SIMLTAL 2048 + + +P + + ++ T+ D T ++ + +N + TE I+LTAL Sbjct: 3951 ISKENVQFIPKKKEITKNNFENSSTVSITLDKELTTSLLRN--TNRAYNTEINDILLTAL 4008 Query: 2049 ALTIRAWTGNAAVVVNLGNHGRDMDSKDIDTYRTVGRFSILYPVALQLPESRNIDLCLEY 2108 A+ R TG + VN+ HGR+ ++ + RTVG F+ +YPV L + + ++ Sbjct: 4009 AVGTRELTGKYKLKVNMEGHGREDVIENFEINRTVGWFTTMYPVLLDIGNENELSTNIKT 4068 Query: 2109 VKEYLSGIPKQGGGYGVLKYLSSHQEGIRFRLNPELSFNYMGQFDAEFNTSTFRISPLSG 2168 VKE L IP +G GYGVLK+L+ + G +SFNY+G+ D + N F S S Sbjct: 4069 VKETLRKIPNKGIGYGVLKHLAKDK-GFMNEEKAPISFNYLGELDQDINRREFSASKWSI 4127 Query: 2169 GEDRSGEEIWSYKLKFISFIRMNQLNIGIEYNQQQYARETVNALLQQYMEYLK 2221 GE + + ++ S + +L I +N+ +Y+ + + L Q+Y E L+ Sbjct: 4128 GETVGKKINRNTSIEMNSMVLNGELVIHTTFNKLEYSEKMIKDLNQKYKESLE 4180 Score = 758 bits (1958), Expect = 0.0, Method: Compositional matrix adjust. Identities = 511/1620 (31%), Positives = 834/1620 (51%), Gaps = 139/1620 (8%) Query: 666 SKAEISVGQVWGAVLGMNPMSVTADFYEIGGDSIIAIEIVNTLNTIMGLSLQVPVLFEHS 725 ++ + + +W V + + + ++YEIGGDS+ AI IV + M + + + +F++ Sbjct: 1589 NETQAQILDIWKDVFEIENIGIDTNYYEIGGDSLKAISIVTEIKKRMNIEVPIGEIFKND 1648 Query: 726 NIERLAAYIEGQAGTDKDTRGNSAIPRIAAAEHYEVSSSQKRIYILNQLNARSTSYNIPL 785 I+ L Y++ + + RGN I R++ ++Y S SQKR+Y+L+ + +Y+IP+ Sbjct: 1649 TIKVLDQYLKN---SQDNHRGNR-IERVSKKDYYATSPSQKRMYMLSMMENNRGAYHIPM 1704 Query: 786 FVMMEGPLDEGRLEHSFEALIQRHEVLRTSFSFVNKELVQAVDDHVHLAVEKYHAD---- 841 +++EG ++ RLE +F I RHE+LRT F ++ ELVQ V D V +E D Sbjct: 1705 ALLVEGEIECNRLEKAFRKFIDRHEILRTGFEVLDNELVQRVYDKVDFDLEYQCLDIVVT 1764 Query: 842 DETDLDQITSQF----IRPFDLSKAPLIRAGLVEIRKNKHLLMLDVQHIIADGSSIPLLQ 897 D+ L +TS+ +PFDL+K L+RA L++I KH+L+++ HIIADG S + Sbjct: 1765 DDEGLRDLTSKMCKESTKPFDLNKPSLMRAKLIKIGVEKHILVVNFHHIIADGVSQGIFM 1824 Query: 898 KEIIHLYEHNPLPELNIQFKDFAKWQNDLFKTDYMNKQKKYWLDVFSGELPILNLPVDYP 957 EI+ LY + LP++NIQ+KD+ +W N +++ + KQ++YWL+++S L LP DY Sbjct: 1825 NEILDLYNNLDLPKINIQYKDYVEWNNTYNQSNAIKKQEQYWLNLYSHLPSKLELPYDYR 1884 Query: 958 RDSGQGDQGERLTCNAGRELTQRLNEYSSKEKTTLFMTLLAAFNVLLFKHTGQEDIIVGS 1017 +++ GE + +EL++++ + +TL+M +L+A+++LL K+TG+ DI+VG+ Sbjct: 1885 KENIDTFAGENAYFHIEKELSEQIRRVAKDTGSTLYMLMLSAYHILLHKYTGKTDIVVGT 1944 Query: 1018 PIAGRKHKELEQMIGMFVNTLALRNRPSAHMVFKEFLAGVKENALQAYEHQDYPFEELVD 1077 +GR H++L+ + G+FVNT+ALRN A FKE L VKEN + A+E+ +Y F+EL+ Sbjct: 1945 AASGRLHQDLQNIFGVFVNTIALRNNIDATKSFKEILEQVKENTITAFENSEYQFDELIR 2004 Query: 1078 HLNMDRNLSGTALFNVMFVLQVMDNPAFEVNGMHYAPYPYHNKTAKFDLALQVFPGLDEL 1137 ++ +R+ + LF+ MFVL+ + ++ +P + AKFD+ + DE+ Sbjct: 2005 SIDYERDSNRNPLFDTMFVLEDAKLFTKKQGALNLSPIIFELDNAKFDITFNILDYDDEI 2064 Query: 1138 KFEFTYAAKLFKRSTIESFARRFLRVLEQVVALEHVLIGDIDVLDREELRD-IRRYGQAG 1196 Y+ LFKR TI ++ +L ++ + + ID++ +EE R + + Sbjct: 2065 VLNVEYSTGLFKRDTILRMTENYINILREISGNLSISVNKIDMIPQEEKRFLLYEHNDTN 2124 Query: 1197 LPAAYNTKTIVEMFEAQAARIPDHLAVSGFDRSLTYRELNEQANQLARVLIRNGACKDRV 1256 + + N + I ++FE Q R PD +AV D+ LTYRELNE++NQLAR L NG D++ Sbjct: 2125 VDFSKN-QLIHKLFEEQVERTPDSIAVVFEDKQLTYRELNEKSNQLARALRENGVGSDKI 2183 Query: 1257 VGIIAERSTNFAVGIMGVLKSGAAYLPIEPAYPPERKRFMLEDSGACMVLT--------D 1308 VGI+ ERS + VGIMG+LK+G AYLPI+P YP +R +++L+DS ++LT D Sbjct: 2184 VGILLERSVDVIVGIMGILKAGGAYLPIDPTYPIDRIKYILQDSQTEILLTQDKLINLVD 2243 Query: 1309 TAHRRSLQHGIREICLEEVAGNSGEQGNLEATASADSLAYVIYTSGSTGKPKGVMIEHRS 1368 + I I E + E NL +S+ L YVIYTSGSTGKPKGVM+EH S Sbjct: 2244 CTEVDDI--SIINIHNEHLFKYGTE--NLRIDSSSKDLVYVIYTSGSTGKPKGVMVEHHS 2299 Query: 1369 VTNLAEALDEKIYSLHGPNLNVALLAPFVFDASVKQIFSAFLLGHHLNIVPGDVRQDVIQ 1428 + NL + ++ A A FDA ++F + G ++I+ +++ D+ + Sbjct: 2300 LVNLCNWHNS--FNKISETDKNASYASISFDAFAWEVFPYIIAGSEIHIINDNLKLDITK 2357 Query: 1429 LAEYYKQNKIDISDGTPAYLRLLAETSLCARI------GVAHFIIGGEALSIAEVKRFYT 1482 L +Y+ + +I IS T +C + + + GG+ L+ E K + Sbjct: 2358 LNKYFIEKEISIS---------FLPTQVCEQFLMLENTSLRRLLTGGDKLNYFENKSY-- 2406 Query: 1483 SFANHKPPYITNVYGPTECCVDATAFTIKPEETGQIQEMPIGAPIKNCSVYILDEQKRMV 1542 I N YGPTE V T+F I+ +PIG PI N V+IL+E + Sbjct: 2407 --------QIVNNYGPTENSVVTTSFIIE----NSYDNIPIGKPICNTKVFILNESNGLC 2454 Query: 1543 PRGVLGELYIGGHGVARGYCNNKALTSSRFVEDIYHPGMYMYKTGDMGKWTEDGLIHFAG 1602 P GV GEL I G G+ARGY N LT+ +F+ + + PG MY+TGD+ + DG I F G Sbjct: 2455 PLGVPGELCISGEGLARGYLNRPELTAEKFIPNPFIPGERMYRTGDLVRMLPDGNIEFLG 2514 Query: 1603 RADHQVKIRGFRIELDEIRHRLLSCDGVQAAVVLVQKDQRQEPYLCAYV---VCRDEQVL 1659 R DHQVKIRGFRIEL EI +LL V+ AVV+ ++D YLCAY + E + Sbjct: 2515 RIDHQVKIRGFRIELGEIESQLLKHKEVKEAVVIAREDNNNHQYLCAYFTSETSKGETRV 2574 Query: 1660 PGLRGYLGEYLPDYMIPRVIMPVDQIPMTANGKADTSQLPDPQEMRDHS-----LGYGAP 1714 +R +L + LP+YMIP + +D++P+T NGK D LP P D S + Y AP Sbjct: 2575 QEIRKFLTKELPEYMIPAFFVQLDKLPLTTNGKVDRKALPSP----DGSSVAGVVEYEAP 2630 Query: 1715 RNRTEEILCTVWSEVLELRRIGIHDNFFAAGGDSIKAIQAAARMEKYNLRLEVK--HLFQ 1772 RN EE L ++W ++L++ IGI NFF GG S+KA +R+ K L +E+ +FQ Sbjct: 2631 RNTVEEKLVSIWQDILDIENIGIQHNFFEIGGHSLKATTMVSRIHK-ELMVEIPLGQIFQ 2689 Query: 1773 YQTIGEVSKKVQDRAGHAGYGAVTG--EAGLVPIQS-----WMVEHCRDTLQHRNLSFVL 1825 TI E+ + + + + Y ++ E P+ S +++ + N+ F + Sbjct: 2690 VPTIKEIGEFI-NSTKESVYASIKKVEEQDYYPLSSAQRRLYILNKIEGSGVSYNMPFAM 2748 Query: 1826 YREAGFGEDNIRKVFTEIIRHHDALRMVFREQNRQMLQHNRGLDGELFDFYLIDLADSPS 1885 + + + F ++I H++LR F +DGE D+ + Sbjct: 2749 KIKGDLDVHQLEQAFRKLIERHESLRTSF-----------VMVDGEPVQKIKKDINSQVT 2797 Query: 1886 FSE----EXXXXXXXXXXSMDLEKGPLVKLALIRAGYGEHLLIV-IHQMIIDHLSWRIIL 1940 + E + DLEK PL+++ +I EH++++ +H +I D +S I + Sbjct: 2798 YREMGTNKLDDIINGFVKPFDLEKAPLLRVEIIHVTDDEHVMVLDMHHIISDGVSMGIFM 2857 Query: 1941 EDFNTAYTQLLNHEDIGLPPKTAPFLQWSNHLHEYADSIELLREQPYWDQV--ESIKAEP 1998 ++ +L N + L P + + +S E+ +++ YW V E + Sbjct: 2858 QEL----AELYNGQK--LSPLSIQYKDYSEWQRGLFTQEEITKQEKYWMNVFNEEVPVLN 2911 Query: 1999 LPTDYKADEARV----RDNLTLYQAFDCTETEQVMSSIRSNPHFTTESIMLTALALTIRA 2054 +PTDYK + R R NL + +ET ++ + + T +ML + Sbjct: 2912 MPTDYKRPKRRSFAGDRINLKI-----NSETYNQLNKLATENEVTMYMLMLAGYTTLLSK 2966 Query: 2055 WTGNAAVVVNLGNHGRDMDSKDIDTYRTVGRFSILYPVALQLPESRNIDLCLEYVKE-YL 2113 ++G +VV GR K +D +G F + +R+ L+ VKE L Sbjct: 2967 YSGQEDIVVGSPIAGR----KHVDLNNVMGMFVNTLAMRNYPKGNRSFREYLKEVKENTL 3022 Query: 2114 SGIPKQGGGYGVLKYLSSHQEGIRFRLNPELSFNYMGQF----DAEFNTSTFRISPLSGG 2169 Q + L + +R ++ F+ M F + N ++S L Sbjct: 3023 KAYENQDYQFEEL----VEKVNVRRDISRNPLFDTMLVFQHTDNMLLNLDGLKVSML--- 3075 Query: 2170 EDRSGEEIWSYKLKFISFIRMNQLNIG----IEYNQQQYARETVNALLQQYMEYLKKAAE 2225 ED+ EI +KF I +++L G IEY Y +ET+ L+ ++ L++ E Sbjct: 3076 EDQ--REI----VKFDITIHVSELEHGLGLEIEYCTALYKKETIERFLEHFINVLREVVE 3129 Score = 494 bits (1271), Expect = e-137, Method: Compositional matrix adjust. Identities = 323/1049 (30%), Positives = 547/1049 (52%), Gaps = 65/1049 (6%) Query: 759 YEVSSSQKRIYILNQLNARSTSYNIPLFVM-MEGPLDEGRLEHSFEALIQRHEVLRTSFS 817 Y +++ QK + + + L +++S VM ++G +D LE SF +++RHE+LR +F Sbjct: 4225 YPLANMQKGM-LFHALEDKNSSMYFEQIVMDIKGTVDVDILEKSFNTIMRRHEILRAAFE 4283 Query: 818 FVNKELVQAVDDHVHLAVE------KYHADDETDLDQITSQFI---------RPFDLSKA 862 + + V++ H+ ++ KY+ + ++Q T +FI + F+LS+ Sbjct: 4284 Y------ELVEEPRHVILQDRKVGFKYYDIQDESIEQKT-KFIENYLQNDKQKGFNLSED 4336 Query: 863 PLIRAGLVEIRKNKHLLMLDVQHIIADGSSIPLLQKEIIHLY------EHNPLPELNIQF 916 L+R L+++ ++ + L+ HI+ DG + ++ E +Y E + L E + Sbjct: 4337 TLMRISLIQMNQDSYKLVWSHHHILLDGWCLGIILGEFFDVYGRKMKGEDSHLAEPT-PY 4395 Query: 917 KDFAKWQNDLFKTDYMNKQKKYWLDVF--SGELP-ILNLPVDYPRDSGQGDQGERLTCNA 973 D+ +W + K + + K Y LD + ++P ILN +Y R Sbjct: 4396 SDYIRWLEEQDKEEGLAHWKSY-LDGYEEQAQVPKILNKVNEYKRKEKM--------IEF 4446 Query: 974 GRELTQRLNEYSSKEKTTLFMTLLAAFNVLLFKHTGQEDIIVGSPIAGRKHKE--LEQMI 1031 +E+ + + + +++ + T L A + +LL ++ ED++ G+ ++GR+ K +E M+ Sbjct: 4447 SKEMNRNIIQLANRNQVTFNTVLQAIWGILLARYNNIEDVVFGTVVSGREAKVEGIEAMV 4506 Query: 1032 GMFVNTLALRNRPSAHMVFKEFLAGVKENALQAYEHQDYPFEELVDHLNMDRNLSGTALF 1091 G+F+NT+ R + FKE L V++ +++ ++ E+ ++ RNL + Sbjct: 4507 GLFINTIPTRVKLEKDSSFKEVLRNVQDESIENNKYNYINLAEIQSLHDLKRNLIDHVM- 4565 Query: 1092 NVMFVLQVMDNPAF---EVNGMHYAPYPYHNKTAKFDLALQVFPGLDELKFEFTYAAKLF 1148 +F +D+ +F E N + + + PG ++L + TY K++ Sbjct: 4566 --VFQNYSLDDSSFNHAESNTGFMCQNIRGEEQTNYGFNIVAIPG-EQLVLKLTYNEKIY 4622 Query: 1149 KRSTIESFARRFLRVLEQVVALEHVLIGDIDVLDREELRDIRRYGQAGLPAAY-NTKTIV 1207 + I++ +V EQVV E + +ID++ +E RD+ Y Y KTI Sbjct: 4623 PQEIIDNIEMHLKKVTEQVVLNEDKKLNEIDIIPEKE-RDVLLYRFNDTKTNYPKDKTIH 4681 Query: 1208 EMFEAQAARIPDHLAVSGFDRSLTYRELNEQANQLARVLIRNGACKDRVVGIIAERSTNF 1267 ++FE Q + P+H+AV +TY+ELNE++NQ+AR L G + +VGI+ ERS Sbjct: 4682 QLFEEQVEKTPNHIAVEFEGTKMTYQELNERSNQVARWLRDKGITANTIVGIMVERSPEM 4741 Query: 1268 AVGIMGVLKSGAAYLPIEPAYPPERKRFMLEDSGACMVLTDTAHRRSLQHGIREICLEEV 1327 +GIMG+LKSG+AYLPI+P P +R +FM++DS ++LT + + L++ Sbjct: 4742 IIGIMGILKSGSAYLPIDPKSPQDRIKFMIQDSDIQILLTQEKFINDSSLDVEMVSLDKS 4801 Query: 1328 AGNSGEQGNLEATASADSLAYVIYTSGSTGKPKGVMIEHRSVTNLAEALDEKIYSLHGPN 1387 + NL ++++AY+IYTSGSTG PKGV+ H + + D + + Sbjct: 4802 ENFQLSKENLAPINDSENIAYIIYTSGSTGVPKGVVTSHSNAVRVVR--DTNYIKIDADD 4859 Query: 1388 LNVALLAPFVFDASVKQIFSAFLLGHHLNIVPGDVRQDVIQLAEYYKQNKIDISDGTPAY 1447 + + L+ + FD SV I+ A L G L +V D ++ +L + K+ KI + T A Sbjct: 4860 I-ILQLSNYSFDGSVFDIYGALLNGAKLVMVSIDTVLNLSKLTKLIKEEKISVMFITTAL 4918 Query: 1448 LRLLAETSLCARIGVAHFIIGGEALSIAEVKRFYTSFANHKPPYITNVYGPTECCVDATA 1507 L + + + + GGE +S++ KR K + +VYGPTE V AT Sbjct: 4919 FNTLVDLEIECLSNIRKILFGGERISVSHTKRALEYLGKDK---LIHVYGPTESTVFATY 4975 Query: 1508 FTIKPEETGQIQEMPIGAPIKNCSVYILDEQKRMVPRGVLGELYIGGHGVARGYCNNKAL 1567 + I E + +PIG P+ N S +I+D +R++P GV GEL + G G+A GY N L Sbjct: 4976 YCIN-EINEEFDTIPIGKPLANTSAFIVDGNQRLLPIGVAGELCLSGAGLAHGYLNRPDL 5034 Query: 1568 TSSRFVEDIYHPGMYMYKTGDMGKWTEDGLIHFAGRADHQVKIRGFRIELDEIRHRLLSC 1627 T+ +FV + + P MY+TGD+ + DG I F GR DHQVK+RGFRIEL EI +LL Sbjct: 5035 TAEKFVSNPFIPEEKMYRTGDLVRMLPDGNIEFLGRIDHQVKVRGFRIELGEIESQLLKY 5094 Query: 1628 DGVQAAVVLVQKDQRQEPYLCAYVVC---RDEQVLPGLRGYLGEYLPDYMIPRVIMPVDQ 1684 V+ A+V+V+ D E Y+CAY +DE ++ +R YL + LP+YMIP + +D+ Sbjct: 5095 KKVKEAIVIVRDDIHGEKYICAYFTSETWKDELIIQEIRKYLTKKLPEYMIPAFFVQLDK 5154 Query: 1685 IPMTANGKADTSQLPDPQEMRDHSLGYGAPRNRTEEILCTVWSEVLELRRIGIHDNFFAA 1744 +P+T NGK D LP P + Y AP N EE + ++W E+L ++ IGI NFF Sbjct: 5155 LPLTTNGKVDRKSLPKPDGNVTTEVEYVAPSNFVEETIISIWEEILGIKSIGISHNFFEI 5214 Query: 1745 GGDSIKAIQAAARMEK-YNLRLEVKHLFQ 1772 GG+S+K + A A + K N + + + F+ Sbjct: 5215 GGNSLKLMSAVAAINKVLNTDISIHNFFE 5243 Score = 476 bits (1224), Expect = e-131, Method: Compositional matrix adjust. Identities = 428/1562 (27%), Positives = 717/1562 (45%), Gaps = 149/1562 (9%) Query: 577 GRTETDILNEICSLYEKGGEVDWESL--YEGEKRGKISIPVYPFLKERHWVNAPRRKTAE 634 R E D N IC+ GEV E L + GEK IP Y FLK P + Sbjct: 469 AREEKDKSNYICAYLTLVGEVTVEELRKFLGEKLPDYMIPTY-FLK---LDKMPLTANGK 524 Query: 635 PDEEEQEGLWQNSLEAAAAGIQLEGRDSGRYSKAEISVGQVWGAVLGMNPMSVTADFYEI 694 D++ SL E S+ E + +W L +N + + F + Sbjct: 525 IDKK--------SLPEPDRSFNTEVEYEEPRSEIEKQLVLMWQETLNINKVGINDSFAVL 576 Query: 695 GGDSIIAIEIVNTLNTIMGLSLQVPVLFEHSNIERLAAYIEGQAGTDKDTRGNSAIPRIA 754 GG SI A+E+++ +N + + L + LF S I++++AYIE G + R + + Sbjct: 577 GGHSINAMELLSKMNDRLSVDLPLKELFRLSTIKKISAYIETNKGEIIENRQFTKTTDLK 636 Query: 755 AA-EHYEVSSSQKRIYILNQLNARSTSYNI-----PLFVMMEGPLDEGRLEHSFEALIQR 808 E + ++ Q L L R ++ I L V E ++ R + + LI R Sbjct: 637 NLHEPFPLTGIQ-----LAYLIGRDPAFEIGGAATNLTVEFEIDINIDRFNSALQKLINR 691 Query: 809 HEVLRT------SFSFVNKELVQAVDDHVHLAVEKYHADDETDLDQITSQ----FIRPFD 858 H +LRT + + EL+ +VD V+ H + E + +I Q + D Sbjct: 692 HPILRTIVFENGTQRILEGELLYSVD-----TVDVRHLNQEDIMIRILEQRQKMIAKIID 746 Query: 859 LSKAPLIRAGLVEIRKNKHLLMLDVQHIIADGSSIPLLQKEIIHLYEHNPL--PELNIQF 916 S PL + N+ L++ +I D SS+ +L KE Y L PEL F Sbjct: 747 PSTWPLFEIKAFILPNNQKYFCLNIDPLICDDSSMKILIKEFKMFYNQPSLQLPELEYNF 806 Query: 917 KDFAKWQNDLFKTDYMNKQKKYWLDVFSG-----ELPILNLPVDYPRDSGQGDQGERLTC 971 +D+ N+ +++ K +KYWL+ LP+ P++ + + + + Sbjct: 807 RDYVLATNEFRQSNRYKKDEKYWLNKLDNFPSAPALPLKCNPLEIEKPTFN-----KCSE 861 Query: 972 NAGRELTQRLNEYSSKEKTTLFMTLLAAFNVLLFKHTGQEDIIVGSPIAGRK--HKELEQ 1029 RE RL + + ++ T L AA+ +L + Q V + R H+++++ Sbjct: 862 FLERETWNRLKQKAREKNLTPTSVLCAAYAYVLAYWSNQSRFAVNLTVFNRIPFHQDVKK 921 Query: 1030 MIGMFVNTLALR-NRPSAHMVFKEFLAGVKENALQAYEHQDYPFEELVDHLNMDRNLSGT 1088 +IG F + L N + F +F A V++ L+A EH+ Y + + + + Sbjct: 922 IIGDFTTLMLLDINAKDSIESFWKFAAKVQDTLLEALEHRHYDGVDFIRAIGKKHRMVNQ 981 Query: 1089 ALFNVMFVLQVMDNPAFEVNGMHYAPYP----YHNKTAKFDLALQVFPGLDELKFEFTYA 1144 A+ ++F + ++ N H + + +T++ + QV+ L + Y Sbjct: 982 AIMPIVFTSVLSEDSDDSFN--HLIDFEKIKFFSTRTSQVYIDNQVYELNGGLYITWDYV 1039 Query: 1145 AKLFKRSTIESFARRFLRVLEQVVALEHVLIGDIDVLDREELRDIRRYGQAGLPAAYNTK 1204 +LF+ + I+S +++ VL QV+ + V I++ D ++ I Y ++ Sbjct: 1040 EQLFEINVIKSMFEQYINVLNQVIFNDQV--SGINLSDNS-IKVIETYNDTN--KKFDKC 1094 Query: 1205 TIVEMFEAQAARIPDHLAVSGFDRSLTYRELNEQANQLARVLIRNGACKDRVVGIIAERS 1264 T+ EMF +A +PD +AV D S+TY+ELNE++NQ+AR L+ G K +G+I +R Sbjct: 1095 TLHEMFVNRAKLVPDKVAVIHHDDSITYKELNEKSNQIARYLMDKGVRKGDYIGVIGKRC 1154 Query: 1265 TNFAVGIMGVLKSGAAYLPIEPAYPPERKRFMLEDSGACMVLTDTAHRRSLQHGIREICL 1324 + + + VLK+GAAY+P++P YP ERK ++ + S +T + ++ IRE Sbjct: 1155 IDTIINLFAVLKAGAAYIPLDPDYPEERKEYIKKKSNCKFFITPSTYK---DENIREY-- 1209 Query: 1325 EEVAGNSGEQGNLEATASADSLAYVIYTSGSTGKPKGVMIEHRSVTNLAEALDEKIYSLH 1384 SG++ N++ + +AYVI+TSGSTGKPKGV I H + TN ++EK Sbjct: 1210 ------SGDEVNIKVDET--DMAYVIFTSGSTGKPKGVQITHGAATNTIIDINEKFCVTE 1261 Query: 1385 GPNLNVALLAPFVFDASVKQIFSAFLLGHHLNIVPGDVRQDVIQLAEYYKQNKIDISDGT 1444 N + ++ FD SV +F A G L I+ D ++DV L + K+ I I + Sbjct: 1262 --NDKIMGISSLCFDLSVYDVFGALSCGAALVII--DDQRDVYNLKKVVKKEGITIWNSV 1317 Query: 1445 PAYLRLL------AETSLCARIGVAHFIIGGEALSIAEVKRFYTSFANHKPPYITNVYGP 1498 PA + L +E R+ ++ G+ + + ++ +F N + + ++ G Sbjct: 1318 PAIMELTVDLYNDSEQDDSLRL----VLLSGDWIPLELPQKIKKTFKNAE---VISLGGA 1370 Query: 1499 TECCVDATAFTIKPEETGQIQEMPIGAPIKNCSVYILDEQKRMVPRGVLGELYIGGHGVA 1558 TE + + + IK E G + +P G P+ N +Y+L++ K++ P V GELYIGG GVA Sbjct: 1371 TEGSIWSIYYPIK-EIKGDWKSIPYGMPLANQKIYVLNQNKQLCPVDVEGELYIGGVGVA 1429 Query: 1559 RGYCNNKALTSSRFVEDIYHPGMYMYKTGDMGKWTEDGLIHFAGRADHQVKIRGFRIELD 1618 GY N+ T F+ ++ Y+YKTGD G EDG + F GR D QVKIRG+R+EL Sbjct: 1430 SGYINDIEKTKMSFI--LHEELGYIYKTGDYGVLKEDGYVEFLGRKDSQVKIRGYRVELG 1487 Query: 1619 EIRHRLLSCDGVQAAVVLVQKDQRQEPYLCAYVVCRDEQVLPG-LRGYLGEYLPDYMIPR 1677 EI + ++ GV VV+ + + L A+VV DE + P L+ YL LP+YMIP Sbjct: 1488 EIENCIIKYKGVNKTVVIDYTNDNKMKSLYAFVVS-DEDINPNELKQYLQNQLPNYMIPS 1546 Query: 1678 VIMPVDQIPMTANGKADTSQLPDPQEMRDHSLGYGA------PRNRTEEILCTVWSEVLE 1731 +D+IP+T NGK + S L + +++H L A N T+ + +W +V E Sbjct: 1547 RFFKIDEIPLTVNGKVNKSILGEL--IKNHELDEVAATTCEESENETQAQILDIWKDVFE 1604 Query: 1732 LRRIGIHDNFFAAGGDSIKAIQAAARMEK-YNLRLEVKHLFQYQTIGEVS---KKVQD-- 1785 + IGI N++ GGDS+KAI ++K N+ + + +F+ TI + K QD Sbjct: 1605 IENIGIDTNYYEIGGDSLKAISIVTEIKKRMNIEVPIGEIFKNDTIKVLDQYLKNSQDNH 1664 Query: 1786 ------RAGHAGYGAVTGEAGLVPIQSWMVEHCRDTLQHRNLSFVLYREAGFGEDNIRKV 1839 R Y A + + + S M+E+ R + L E + + K Sbjct: 1665 RGNRIERVSKKDYYATSPSQKRMYMLS-MMENNRGAYH---IPMALLVEGEIECNRLEKA 1720 Query: 1840 FTEIIRHHDALRMVFREQNRQMLQHNRGLDGELFD--FYLIDL--ADSPSFSEEXXXXXX 1895 F + I H+ LR F + +++Q R D FD + +D+ D + Sbjct: 1721 FRKFIDRHEILRTGFEVLDNELVQ--RVYDKVDFDLEYQCLDIVVTDDEGLRDLTSKMCK 1778 Query: 1896 XXXXSMDLEKGPLVKLALIRAGYGEHLLIV-IHQMIIDHLSWRIILEDFNTAYTQLLNHE 1954 DL K L++ LI+ G +H+L+V H +I D +S I + + Y L Sbjct: 1779 ESTKPFDLNKPSLMRAKLIKIGVEKHILVVNFHHIIADGVSQGIFMNEILDLYNNL---- 1834 Query: 1955 DIGLPP---KTAPFLQWSNHLHEYADSIELLREQPYWDQVES---IKAEPLPTDYKADEA 2008 LP + +++W+N Y S + +++ YW + S K E LP DY+ + Sbjct: 1835 --DLPKINIQYKDYVEWNN---TYNQSNAIKKQEQYWLNLYSHLPSKLE-LPYDYRKENI 1888 Query: 2009 RVRDNLTLYQAFDCTETEQVMSSIRSNPHFTTESIMLTALALTIRAWTGNAAVVVNLGNH 2068 Y + +EQ+ + + T +ML+A + + +TG +VV Sbjct: 1889 DTFAGENAYFHIEKELSEQI-RRVAKDTGSTLYMLMLSAYHILLHKYTGKTDIVVGTAAS 1947 Query: 2069 GR 2070 GR Sbjct: 1948 GR 1949 Score = 454 bits (1168), Expect = e-125, Method: Compositional matrix adjust. Identities = 290/925 (31%), Positives = 458/925 (49%), Gaps = 57/925 (6%) Query: 1204 KTIVEMFEAQAARIPDHLAVSGFDRSLTYRELNEQANQLARVLIRNGACKDRVVGIIAER 1263 KTI ++FE Q R P+++AV D+ LTYR+LNE++NQLAR+L G D ++G++ +R Sbjct: 43 KTINQLFEEQVERTPENIAVVFKDKQLTYRQLNEKSNQLARMLRNKGVNTDAIIGLMIDR 102 Query: 1264 STNFAVGIMGVLKSGAAYLPIEPAYPPERKRFMLEDSGACMVLTDTAHRRSLQHGIREIC 1323 S +GIMG+LKSGAAYLPI+P P R +ML DS ++LT + +++ + I Sbjct: 103 SLEMIIGIMGILKSGAAYLPIDPDTPKARIDYMLRDSHTMILLTQEKFIKKIEYDLEIIN 162 Query: 1324 LEEVAGNSGEQGNLEATASADSLAYVIYTSGSTGKPKGVMIEHRSVTNLAEALDEKIYSL 1383 L+E+ + GNL+ D AY+IYTSGSTG PKGV+I H S + + Y Sbjct: 163 LDELDSSDLSTGNLKHINRFDDTAYIIYTSGSTGIPKGVIISHYSAIRVVRNTN---YIE 219 Query: 1384 HGPNLNVALLAPFVFDASVKQIFSAFLLGHHLNIVPGDVRQDVIQLAEYYKQNKIDISDG 1443 N + L+ + FD S+ I+ A L G L ++ D D+ +L KQ I++ Sbjct: 220 INNNDTILQLSNYSFDGSIFDIYGALLNGAKLVVIEKDTVTDINKLGNIIKQENINVMFI 279 Query: 1444 TPAYLRLLAETSLCARIGVAHFIIGGEALSIAEVKRFYTSFANHKPPYITNVYGPTECCV 1503 T A L + + I + + GGE +S++ ++ K + +VYGPTE V Sbjct: 280 TTALFNALVDIKIDCLINMRKILFGGERISVSHARKALEFLGKDK---LIHVYGPTESTV 336 Query: 1504 DATAFTIKPEETGQIQEMPIGAPIKNCSVYILDEQKRMVPRGVLGELYIGGHGVARGYCN 1563 AT + I E + +PIG P+ N SVYI+DE+K ++P G GEL I G G+ +GY N Sbjct: 337 FATYYFIN-EIDEDVDTLPIGKPLANTSVYIVDEKKNLLPIGEPGELCISGDGLTKGYLN 395 Query: 1564 NKALTSSRFVEDIYHPGMYMYKTGDMGKWTEDGLIHFAGRADHQVKIRGFRIELDEIRHR 1623 N+ LT +FV++ + G +Y+TGD+ +W DG I F GR DHQVK+RGFRIEL EI + Sbjct: 396 NEQLTLEKFVKNPFAEGERLYRTGDLARWLPDGNIEFIGRIDHQVKVRGFRIELGEIESQ 455 Query: 1624 LLSCDGVQAAVVLVQKDQRQEPYLCAYVVCRDEQVLPGLRGYLGEYLPDYMIPRVIMPVD 1683 LL V+ VV+ ++++ + Y+CAY+ E + LR +LGE LPDYMIP + +D Sbjct: 456 LLKHPNVKETVVVAREEKDKSNYICAYLTLVGEVTVEELRKFLGEKLPDYMIPTYFLKLD 515 Query: 1684 QIPMTANGKADTSQLPDPQEMRDHSLGYGAPRNRTEEILCTVWSEVLELRRIGIHDNFFA 1743 ++P+TANGK D LP+P + + Y PR+ E+ L +W E L + ++GI+D+F Sbjct: 516 KMPLTANGKIDKKSLPEPDRSFNTEVEYEEPRSEIEKQLVLMWQETLNINKVGINDSFAV 575 Query: 1744 AGGDSIKAIQAAARM-EKYNLRLEVKHLFQYQTIGEVSKKVQDRAGHAGYGAVTGEAGLV 1802 GG SI A++ ++M ++ ++ L +K LF+ TI ++S ++ G + Sbjct: 576 LGGHSINAMELLSKMNDRLSVDLPLKELFRLSTIKKISAYIETNKGE-----IIENRQFT 630 Query: 1803 PIQSWMVEHCRDTLQHRNLSFVLYREAGF-----------------GEDNIRKVFTEIIR 1845 H L L++++ R+ F D ++I Sbjct: 631 KTTDLKNLHEPFPLTGIQLAYLIGRDPAFEIGGAATNLTVEFEIDINIDRFNSALQKLIN 690 Query: 1846 HHDALRMVFREQNRQMLQHNRGLDGELFDFYLIDLADSPSFSEEXXXXXXXXXXS----- 1900 H LR + E Q R L+GEL Y +D D ++E Sbjct: 691 RHPILRTIVFENGTQ-----RILEGEL--LYSVDTVDVRHLNQEDIMIRILEQRQKMIAK 743 Query: 1901 -MDLEKGPLVKL-ALIRAGYGEHLLIVIHQMIIDHLSWRIILEDFNTAYTQLLNHEDIGL 1958 +D PL ++ A I ++ + I +I D S +I++++F Y N + L Sbjct: 744 IIDPSTWPLFEIKAFILPNNQKYFCLNIDPLICDDSSMKILIKEFKMFY----NQPSLQL 799 Query: 1959 PPKTAPFLQWSNHLHEYADSIELLREQPYW----DQVESIKAEPLPTDYKADEARVRDNL 2014 P F + +E+ S +++ YW D S A PL + E + Sbjct: 800 PELEYNFRDYVLATNEFRQSNRYKKDEKYWLNKLDNFPSAPALPLKCNPLEIEKPTFNKC 859 Query: 2015 TLYQAFDCTETEQVMSSIRSNPHFTTESIMLTALALTIRAWTGNAAVVVNLGNHGRDMDS 2074 + F ET + + T S++ A A + W+ + VNL R Sbjct: 860 S---EFLERETWNRLKQKAREKNLTPTSVLCAAYAYVLAYWSNQSRFAVNLTVFNRIPFH 916 Query: 2075 KDIDTYRTVGRFSILYPVALQLPES 2099 +D+ + +G F+ L + + +S Sbjct: 917 QDVK--KIIGDFTTLMLLDINAKDS 939 Score = 77.0 bits (188), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 83/388 (21%), Positives = 174/388 (44%), Gaps = 35/388 (9%) Query: 666 SKAEISVGQVWGAVLGMNPMSVTADFYEIGGDSIIAIEIVNTLNTIMGLSLQVPVLFEHS 725 ++ E + ++W +++G+ + + +F+ GGDSI AI+I++ L+ I GL L++ LF + Sbjct: 3675 NEVEEKLFEIWRSIIGIEDIGINHNFFVSGGDSIKAIQIISRLSRI-GLKLEMKDLFANP 3733 Query: 726 NIERLAAYIEGQAGTDKDTRGNSAIPRIAAAEHYEVSSSQKRIYILNQLNARSTSYNIPL 785 I+ L YI+ + K + + + + +Q+ I+ NQ Sbjct: 3734 KIKNLGKYIKREKKEQKVHEIVNGEVELTPIQSWYFEKNQEEIHHFNQ----------SF 3783 Query: 786 FVMMEGPLDEGRLEHSFEALIQRHEVLRTSFSFVNKELVQ--------AVDDHVHLAVEK 837 + E DE ++E F +++ H+ LR + E++Q D ++H K Sbjct: 3784 MLFRENGFDEKQIEEVFNKIMEHHDALRMIYKEKEGEIIQYNRGYDKNLFDLYIHDV--K 3841 Query: 838 YHADDETDLDQITSQFIRPFDLSKAPLIRAGLVEIRKNKHLLMLDVQHIIADGSSIPLLQ 897 + E + +I + + D+ + L++ + + + HLL+ + H++ DG S +L Sbjct: 3842 GVENKEEKVYEIATNIQKEMDIKEGKLVKLCIFKSDEGDHLLIA-IHHLVVDGVSWRILL 3900 Query: 898 KEIIHLYEHNPLPE-LNIQF-----KDFAKWQNDLFKTDYMNKQKKYWLDVFSGELPILN 951 +++ LY E L I F K+FA + + K+++YW + + + Sbjct: 3901 EDLETLYSQLEKGEKLEIGFKTDSYKEFASKLKAYSVSRELMKEREYWTSISKENVQFIP 3960 Query: 952 LPVDYPRDSGQGDQGERLTCNAGRELTQRLNEYSSKE-KTTLFMTLLAAFNVLLFKHTGQ 1010 + +++ + +T + +ELT L +++ T + LL A V + TG+ Sbjct: 3961 KKKEITKNNFENSSTVSITLD--KELTTSLLRNTNRAYNTEINDILLTALAVGTRELTGK 4018 Query: 1011 EDIIVGSPIAGR----KHKELEQMIGMF 1034 + V GR ++ E+ + +G F Sbjct: 4019 YKLKVNMEGHGREDVIENFEINRTVGWF 4046 >C1FRI9.1 C1FRI9_CLOBJ Amino acid adenylation domain protein Length = 3852 Score = 1126 bits (2913), Expect = 0.0, Method: Compositional matrix adjust. Identities = 600/1550 (38%), Positives = 937/1550 (60%), Gaps = 44/1550 (2%) Query: 675 VWGAVLGMNPMSVTADFYEIGGDSIIAIEIVNTLNTIMGLSLQVPVLFEHSNIERLAAYI 734 +W VLG+ + + +F+E+GG S+ A IV+ + + + + + + +F++ I+ + YI Sbjct: 2294 IWREVLGVENIGLNDNFFELGGHSLNATTIVSKIYSKLEVDVPLEEVFKNQTIKGIYEYI 2353 Query: 735 EGQAGTDKDTRGNSAIPRIAAAEHYEVSSSQKRIYILNQLNARSTSYNIPLFVMMEGPLD 794 + ++ S+I I E YE SS+QKR+Y L +L+ +S +YN+P+ + +EG L+ Sbjct: 2354 KS-----RERSICSSIQLIGEKEFYEASSAQKRMYTLQKLDEKSIAYNMPIVMKIEGKLN 2408 Query: 795 EGRLEHSFEALIQRHEVLRTSFSFVNKELVQAVDDHVHLAVEKYHADDETDLDQITSQFI 854 + RLE + LI+RHE LRTSF V++++VQ V+ + + Y + + +DQI +FI Sbjct: 2409 KERLEKAVMELIKRHEALRTSFEIVDEKIVQKVNKAIKFNI-NYIQETDKSIDQIIKEFI 2467 Query: 855 RPFDLSKAPLIRAGLVEIRKNKHLLMLDVQHIIADGSSIPLLQKEIIHLYEHNPLPELNI 914 PFDL K L R + EI +LL +D+ HI++DG S+ +L KE LY L L + Sbjct: 2468 SPFDLEKPSLFRVAIAEIIGENYLL-IDMHHIVSDGISMDILIKEFTALYNGKTLKPLKV 2526 Query: 915 QFKDFAKWQNDLFKTDYMNKQKKYWLDVFSGELPILNLPVDYPRDSGQGDQGERLTCNAG 974 Q+KDFA WQN+L +++ M +++YW++ F+ E+P+LN+P DY R S +G+R+ + Sbjct: 2527 QYKDFAAWQNNLLRSEVMKSKEEYWMNRFNDEIPVLNMPTDYTRPSIMNFEGDRINFSIE 2586 Query: 975 RELTQRLNEYSSKEKTTLFMTLLAAFNVLLFKHTGQEDIIVGSPIAGRKHKELEQMIGMF 1034 +++T R+ + + + +T++M LL+ N+LL K++GQEDII+GSPIAGR H +LE +IGMF Sbjct: 2587 KDITNRIRKIARETGSTIYMILLSGLNILLSKYSGQEDIIIGSPIAGRTHVDLEPIIGMF 2646 Query: 1035 VNTLALRNRPSAHMVFKEFLAGVKENALQAYEHQDYPFEELVDHLNMDRNLSGTALFNVM 1094 VNT+A+RN P +KEFL VKENAL+AYE+QDY FEELVD LN+ R++S LF+VM Sbjct: 2647 VNTIAMRNYPRGEKTYKEFLKEVKENALRAYENQDYQFEELVDKLNIIRDMSRNPLFDVM 2706 Query: 1095 FVLQVMDNPAFE---VNGMHYAPYPYHNKTAKFDLALQVFPGLDELKFEFTYAAKLFKRS 1151 F +Q MD E ++ + + Y +N +KFDL L +E+ Y +L+KR Sbjct: 2707 FTMQNMDIEDIENIAIDDLKFELYDTYNNISKFDLTLSAIEIEEEILLSIEYNTRLYKRE 2766 Query: 1152 TIESFARRFLRVLEQVVALEHVLIGDIDVLDREELRDIRRYGQAGLPAAY-NTKTIVEMF 1210 TIE F R+L + + + + D + EE ++ Y Y K I E+F Sbjct: 2767 TIEKMINHFSRILSNL-SKDIYIKIDEIEIIEEEEKNQILYEFNDTKVEYPKDKAIQELF 2825 Query: 1211 EAQAARIPDHLAVSGFDRSLTYRELNEQANQLARVLIRNGACKDRVVGIIAERSTNFAVG 1270 E Q + P+++AV D+ LTYRELNE+AN LARVL G D +VGI+ ERS VG Sbjct: 2826 EEQVEKTPNNIAVVFEDKKLTYRELNEKANSLARVLRDKGVKADSIVGIMVERSIEMIVG 2885 Query: 1271 IMGVLKSGAAYLPIEPAYPPERKRFMLEDSGACMVLTDTAHRRSLQHGIREICLEEVAGN 1330 IMG+LKSG AYLPI+P+YP ER +M+ED+ +++T ++ + ++E + Sbjct: 2886 IMGILKSGGAYLPIDPSYPVERIEYMIEDAKIDILITSEEFINKVKFTKSIVNIKEKS-- 2943 Query: 1331 SGEQGNLEATASADSLAYVIYTSGSTGKPKGVMIEHRSVTNLAEALDEKIYSLHGPNLNV 1390 ++ NL+ + LAYVIYTSGSTG+PKGVM+EH+S+ NL ++K +++ + + Sbjct: 2944 LLKKDNLDIINKSSDLAYVIYTSGSTGRPKGVMVEHKSLINLCNYHNKK-FNIKEEDKST 3002 Query: 1391 ALLAPFVFDASVKQIFSAFLLGHHLNIVPGDVRQDVIQLAEYYKQNKIDISD-GTPAYLR 1449 + A F FDASV ++F ++G + I+ +++ D+I+L +YY++N I IS TP + Sbjct: 3003 SY-AEFSFDASVWEVFPYLIIGATIYIINENIKLDIIKLNKYYEKNNITISFLPTPICQQ 3061 Query: 1450 LLAETSLCARIGVAHFIIGGEALSIAEVKRFYTSFANHKPPYIT--NVYGPTECCVDATA 1507 + + R+ + GG+ L+ N+K I+ N YGPTE V T+ Sbjct: 3062 FMEVDNTSLRV----ILTGGDKLN------------NYKEKQISIINNYGPTEATVLTTS 3105 Query: 1508 FTIKPEETGQIQEMPIGAPIKNCSVYILDEQKRMVPRGVLGELYIGGHGVARGYCNNKAL 1567 + +K ++ +PIG P+ N VYIL+ K++ P GV GEL I G G+ARGY NN L Sbjct: 3106 YNVK----SKVNNIPIGKPMYNQRVYILN-NKKVAPIGVSGELCISGDGLARGYLNNPEL 3160 Query: 1568 TSSRFVEDIYHPGMYMYKTGDMGKWTEDGLIHFAGRADHQVKIRGFRIELDEIRHRLLSC 1627 TS +FV++ + PG MY+TGD+ +W DG I F GR D+QVKIRGFRIEL+EI +RLL Sbjct: 3161 TSEKFVDNPFEPGERMYRTGDLARWLPDGNIEFLGRIDNQVKIRGFRIELEEIENRLLEY 3220 Query: 1628 DGVQAAVVLVQKDQRQEPYLCAYVVCRDEQVLPGLRGYLGEYLPDYMIPRVIMPVDQIPM 1687 +GV+ AVV+ ++D+ + YLCAY+V ++ L+ YL + LP+YMIP + + +IP+ Sbjct: 3221 EGVKEAVVVAKEDKERSKYLCAYIVSNNKIDRNELKNYLLKDLPEYMIPLNFVNIKKIPL 3280 Query: 1688 TANGKADTSQLPDPQEMRDHSLGYGAPRNRTEEILCTVWSEVLELRRIGIHDNFFAAGGD 1747 T+NGK D L + +++ + PRN EE++ V+ EVL + +GI+ +FF GGD Sbjct: 3281 TSNGKVDRKILENREDLINIYEECEKPRNSMEEVMIEVFKEVLGVENLGINHSFFDLGGD 3340 Query: 1748 SIKAIQAAARMEKYNLRLEVKHLFQYQTIGEVSKKVQ-DRAGHAGYGAVTGEAGLVPIQS 1806 SIKAI+ ++++K+ +LE+K LF+Y TI +VS ++ + V G+ L+PIQ Sbjct: 3341 SIKAIRLISKLKKHGYKLEIKDLFKYNTIKDVSNRITLEENSIINQELVKGKIDLIPIQK 3400 Query: 1807 WMVEHCRDTLQHRNLSFVLYREAGFGEDNIRKVFTEIIRHHDALRMVFREQNRQMLQHNR 1866 W E H N + +L+ E GF E I+KVF +I HHDALR+VF+ + +LQ NR Sbjct: 3401 WFFEKDFIDNHHWNQAVMLFNEEGFNESIIKKVFDKITEHHDALRIVFKNEKEDVLQFNR 3460 Query: 1867 GLDGELFDFYLIDLADSPSFSEEXXXXXXXXXXSMDLEKGPLVKLALIRAGYGEHLLIVI 1926 GL+GEL+ + D ++ +E S++L GPLVKL + + G+HLLIVI Sbjct: 3461 GLEGELYSLEVFDYRSVENYKKEIENKCNKLQSSINLSNGPLVKLGMFKTKEGDHLLIVI 3520 Query: 1927 HQMIIDHLSWRIILEDFNTAYTQLLNHEDIGLPPKTAPFLQWSNHLHEYADSIELLREQP 1986 H ++ID +SWRI+LEDF+ Y LN++ I L KT F +WS ++ EYA+S +LL+E+ Sbjct: 3521 HHLVIDGVSWRILLEDFSLIYNMELNNKPITLQEKTNSFKEWSTYIKEYANSKDLLQEEE 3580 Query: 1987 YWDQVESIKAEPLPTDYKADEARVRDNLTLYQAFDCTETEQVMSSIRSNPHFTTESIMLT 2046 YW+ +E+ K + +P D + ++ +DN ++ +TE ++ ++ + I+LT Sbjct: 3581 YWENIENTKIKKVPKDNEIKDSIFKDNRSISIRLSEEDTENLLRNVNKAYNTEINDILLT 3640 Query: 2047 ALALTIRAWTGNAAVVVNLGNHGRDMDSKDIDTYRTVGRFSILYPVALQLPESRNIDLCL 2106 AL LTI+ W+ V++NL HGR+ S +I+ RT+G F+ YP+ L + ++I + Sbjct: 3641 ALGLTIKQWSKENKVLINLEGHGREEFSSNINVSRTIGWFTNQYPLVLDISRDKDISYEI 3700 Query: 2107 EYVKEYLSGIPKQGGGYGVLKYLSSHQEGIRFRLNPELSFNYMGQFDAEFNTSTFRISPL 2166 + KE L +P +G GYG+L+Y+ + + +NPE+SFNY+GQFD E ++ F+IS L Sbjct: 3701 KNTKETLRRVPNKGMGYGILRYIKNKWDN---NINPEISFNYLGQFDEEIKSNVFKISNL 3757 Query: 2167 SGGEDRSGEEIWSYKLKFISFIRMNQLNIGIEYNQQQYARETVNALLQQY 2216 G+ S +Y L I LN+ YN ++Y ET+ + Y Sbjct: 3758 PIGQSMSLNSENTYCLNINGMISNGVLNMNFGYNSKEYNEETIKEISNNY 3807 Score = 919 bits (2376), Expect = 0.0, Method: Compositional matrix adjust. Identities = 484/1286 (37%), Positives = 753/1286 (58%), Gaps = 30/1286 (2%) Query: 934 KQK-KYWLDVFSGELPILNLPVDYPRDSGQGDQGERLTCNAGRELTQRLNEYSSKEKTTL 992 KQK +YW++ SGEL ++LP Y + + + + L + + Sbjct: 17 KQKLEYWINTLSGELKPIDLPCKYNNNYKYNKEYGTINIKISQSEYDNLITLNKNSDIAI 76 Query: 993 FMTLLAAFNVLLFKHTGQEDIIVGSPIAGRKHKELEQMIGMFVNTLALRNRPSAHMVFKE 1052 ++TLL+ FN L+ K+TG ++++GSP+ K K + +I A+R+ + FK+ Sbjct: 77 YITLLSVFNSLISKYTGNTEVMIGSPVLKDKDKIVNSLI-------AIRSNICLNDTFKQ 129 Query: 1053 FLAGVKENALQAYEHQDYPFEELVDHLNMDRNLSGTALFNVMFVLQVMDNPAFEVNGMHY 1112 L KE L+AY++Q+YP ++ ++ ++ ++ NV+F ++ + F Sbjct: 130 ILLKTKEITLEAYKNQNYPMNTVLKNIGLEEKYF-YSMLNVIFAMENIHELEFL------ 182 Query: 1113 APYPYHNKTAKFDLALQVFPGLDELKFEFTYAAKLFKRSTIESFARRFLRVLEQVVALEH 1172 ++ ++DL + + E Y F ++ I ++R+L+ ++ + Sbjct: 183 -------ESYQYDLLFLWKRECNGIFCEIKYNVDAFNKADINIMINYYIRILKYILNDIN 235 Query: 1173 VLIGDIDVLDREELRDIRRYGQAGLPAAYNTKTIVEMFEAQAARIPDHLAVSGFDRSLTY 1232 ++I DI+++ EE + KTI E+FE Q R PD++A+ D+ LTY Sbjct: 236 IMIKDINLITEEEKNKLLYEFNDTYTKYLKDKTIQELFEEQVERTPDNIAMVFEDKKLTY 295 Query: 1233 RELNEQANQLARVLIRNGACKDRVVGIIAERSTNFAVGIMGVLKSGAAYLPIEPAYPPER 1292 RELNE+AN +ARVL GA D +VGI+ ERS VGI+G+LKSG AYLPI+P P R Sbjct: 296 RELNEKANSIARVLRDKGAKADSIVGIMVERSIEMIVGIIGILKSGGAYLPIDPYLPKGR 355 Query: 1293 KRFMLEDSGACMVLTDTAHRRSLQHGIREICLEEVAGNSGEQGNLEATASADSLAYVIYT 1352 M++DS + ++LT ++ + I L + NLE ++ LAYVIYT Sbjct: 356 ILHMIQDSHSNILLTTEEFLEDIKFNVEIINLSNRNLYKHKNSNLEIINKSNDLAYVIYT 415 Query: 1353 SGSTGKPKGVMIEHRSVTNLAEALDEKIYSLHGPNLNVALLAPFVFDASVKQIFSAFLLG 1412 SGSTG PKGVMIEH+S+ NL + IYS + L VALLAP+ FDASVKQIF A + G Sbjct: 416 SGSTGSPKGVMIEHKSINNLVLEFKKSIYSKYNEKLRVALLAPYYFDASVKQIFVALIEG 475 Query: 1413 HHLNIVPGDVRQDVIQLAEYYKQNKIDISDGTPAYLRLLAE-TSLCARIGVAHFIIGGEA 1471 H L I D+R+D +L +YYK NKID+SDGTP+++ +++ + + + H IIGG+ Sbjct: 476 HTLYITNEDIRKDGEELLKYYKVNKIDVSDGTPSHINMISYYLNEFKDLTIKHLIIGGDI 535 Query: 1472 LSIAEVKRFYTSFANHKPPYITNVYGPTECCVDATAFTIKPEETGQIQEMPIGAPIKNCS 1531 L+ VK+ + + K I+NVYGPTECCVD + +T++ E+ ++ M IG PI NC Sbjct: 536 LNQTHVKKVFKILEDIK---ISNVYGPTECCVDCSIYTMEQEKNKNMENMSIGRPISNCE 592 Query: 1532 VYILDEQKRMVPRGVLGELYIGGHGVARGYCNNKALTSSRFVEDIYHPGMYMYKTGDMGK 1591 +YILD+ ++ P GVLGEL I G G+ARGY NN LT+ +FV++ + PG+ MYKTGD+ + Sbjct: 593 IYILDKDYKLAPIGVLGELCISGDGLARGYLNNPELTAEKFVDNPFEPGIKMYKTGDLAR 652 Query: 1592 WTEDGLIHFAGRADHQVKIRGFRIELDEIRHRLLSCDGVQAAVVLVQKDQRQEPYLCAYV 1651 W DG I F GR D+QVKIRGFRIEL+EI +RLL +GV+ AVV+ ++D+ + YLCAY+ Sbjct: 653 WLPDGNIEFLGRIDNQVKIRGFRIELEEIENRLLEYEGVKEAVVVAKEDKERSKYLCAYI 712 Query: 1652 VCRDEQVLPGLRGYLGEYLPDYMIPRVIMPVDQIPMTANGKADTSQLPDPQEMRDHSLGY 1711 V ++ L+ YL + LP+YMIP + + +IP+T+NGK D L + +++ + Sbjct: 713 VSNNKIDRNELKNYLLKDLPEYMIPLNFVNIKKIPLTSNGKVDRKILENREDLINIYEEC 772 Query: 1712 GAPRNRTEEILCTVWSEVLELRRIGIHDNFFAAGGDSIKAIQAAARMEKYNLRLEVKHLF 1771 PRN EE++ V+ EVL + +GI+ +FF GGDSIKAI+ ++++K+ +LE+K LF Sbjct: 773 EKPRNSMEEVMIEVFKEVLGVENLGINHSFFDLGGDSIKAIRLISKLKKHGYKLEIKDLF 832 Query: 1772 QYQTIGEVSKKVQ-DRAGHAGYGAVTGEAGLVPIQSWMVEHCRDTLQHRNLSFVLYREAG 1830 +Y TI +VS ++ + V G+ L+PIQ W E H N + +L+ E G Sbjct: 833 KYNTIKDVSNRITLEENSIINQELVKGKIDLIPIQKWFFEKDFIDNHHWNQAVMLFNEEG 892 Query: 1831 FGEDNIRKVFTEIIRHHDALRMVFREQNRQMLQHNRGLDGELFDFYLIDLADSPSFSEEX 1890 F E I+KVF +I HHDALR+VF+ + +LQ NRGL+GEL+ + D ++ +E Sbjct: 893 FNESIIKKVFDKITEHHDALRIVFKNEKEDVLQFNRGLEGELYSLEVFDYRSVENYKKEI 952 Query: 1891 XXXXXXXXXSMDLEKGPLVKLALIRAGYGEHLLIVIHQMIIDHLSWRIILEDFNTAYTQL 1950 S++L GPLVKL + + G+HLLI IH ++ID +SWRI+LEDF+ Y Sbjct: 953 ENKCNKLQSSINLSNGPLVKLGMFKTKEGDHLLIFIHHLVIDGVSWRILLEDFSLIYNME 1012 Query: 1951 LNHEDIGLPPKTAPFLQWSNHLHEYADSIELLREQPYWDQVESIKAEPLPTDYKADEARV 2010 LN++ I L KT F +WS ++ EYA+S +LL+E+ YW+ +E+ K + +P D + ++ Sbjct: 1013 LNNKPITLQEKTNSFKEWSTYIKEYANSKDLLQEEEYWENIENTKIKKIPKDNEIKDSIF 1072 Query: 2011 RDNLTLYQAFDCTETEQVMSSIRSNPHFTTESIMLTALALTIRAWTGNAAVVVNLGNHGR 2070 +DN ++ +TE ++ ++ + I+LTAL LTI+ W+ V++NL HGR Sbjct: 1073 KDNRSISIRLSEEDTENLLRNVNKAYNTEINDILLTALGLTIKQWSKENKVLINLEGHGR 1132 Query: 2071 DMDSKDIDTYRTVGRFSILYPVALQLPESRNIDLCLEYVKEYLSGIPKQGGGYGVLKYLS 2130 + S +I+ RT+G F+ YP+ L + + ++I ++ KE L +P +G GYG+L+Y+ Sbjct: 1133 EEFSSNINVSRTIGWFTNQYPLVLDISKDKDISYEIKNTKETLRRVPNKGMGYGILRYIK 1192 Query: 2131 SHQEGIRFRLNPELSFNYMGQFDAEFNTSTFRISPLSGGEDRSGEEIWSYKLKFISFIRM 2190 + + +NPE+SFNY+GQFD E ++ F+IS L G+ S +Y L I Sbjct: 1193 NKWDN---NINPEISFNYLGQFDEEIKSNVFKISNLPIGQSMSLNSENTYCLNINGMISN 1249 Query: 2191 NQLNIGIEYNQQQYARETVNALLQQY 2216 LN+ YN ++Y ET+ + Y Sbjct: 1250 GVLNMNFGYNSKEYNEETIKEISNNY 1275 Score = 540 bits (1391), Expect = e-151, Method: Compositional matrix adjust. Identities = 356/1258 (28%), Positives = 639/1258 (50%), Gaps = 67/1258 (5%) Query: 778 STSYNIPLFVMMEGPLDEGRLEHSFEALIQRHEVLRTSFSFVNKELVQAV---DDHVHLA 834 S+SY ++G +D E SF +I+R+++LRT F + N + + + + + Sbjct: 1346 SSSYFEQSIFTLKGEIDLNIFERSFNKVIERYDILRTVFVYENVDKPKQIVFKERKARIG 1405 Query: 835 VEKYHADDETDLDQITSQFI-----RPFDLSKAPLIRAGLVEIRKNKHLLMLDVQHIIAD 889 E + FI + F+L K LI+ ++++ K+K+ ++ HI+ D Sbjct: 1406 YEDISKLSNESKENYIENFISKDKEKGFNLGKDLLIKISILKVEKDKYEVVWSFHHILMD 1465 Query: 890 GSSIPLLQKEIIHLYEH------NPLPELNIQFKDFAKWQNDLFKTDYMNKQKKYWLDVF 943 G + ++ + ++Y LP++ + ++ KW D K + N+ ++YW + Sbjct: 1466 GWCLNIIMNDFFNIYSQLQEEKSIELPKVT-PYIEYIKWLEDRKKLN--NEGEEYWRNYL 1522 Query: 944 SGELPILNLPVDYPRDSGQGDQGERLTCNAGRELTQRLNEYSSKEKTTLFMTLLAAFNVL 1003 S + +P+ R + + + L +E T++L E+ T+ + A + +L Sbjct: 1523 SCYENVARIPISAERHKEEKYELKELKFAINKEKTKKLERIVKTERVTMNTIIQAVWGIL 1582 Query: 1004 LFKHTGQEDIIVGSPIAGRKH--KELEQMIGMFVNTLALRNRPSAHMVFKEFLAGVKENA 1061 L ++ +D++ G+ ++GR + +++M+G+F+NT+ +R + + M F E + +++ + Sbjct: 1583 LQRYNNIDDVVFGTVVSGRNANIEGIDRMVGLFINTIPVRIKTESGMSFVELIKEIQKLS 1642 Query: 1062 LQAYEHQDYPFEELVDHLNMDRNLSGTALFNVMFVLQVMDNPAFEVNGMHYAPYPYHNKT 1121 L++ ++ YP E+ + L V++ +DN + +N + N Sbjct: 1643 LESSKYDYYPLAEIQSKTKLKNELINNI---VVYENYYIDNSSINLNEKINKKFIMENMK 1699 Query: 1122 AK----FDLALQVFPGLDELKFEFTYAAKLFKRSTIESFARRFLRVLEQVVALEHVLIGD 1177 ++ +DL L + P +EL + Y K++ IE +++F +++ +++ +++L+ Sbjct: 1700 SREETNYDLNLIIGPS-EELNIKLLYNKKIYDDYIIEKISKQFALIIDTIISNKNILVDK 1758 Query: 1178 IDVLDREELRDI-RRYGQAGLPAAYNTKTIVEMFEAQAARIPDHLAVSGFDRSLTYRELN 1236 I++++ EE + I + + N KTI E+FE Q + P+++AV D+ LTYRELN Sbjct: 1759 IEIIEEEEKKQILYEFNDTKVDYPKN-KTIQELFEEQVEKTPNNIAVVFEDKKLTYRELN 1817 Query: 1237 EQANQLARVLIRNGACKDRVVGIIAERSTNFAVGIMGVLKSGAAYLPIEPAYPPERKRFM 1296 E+AN++A +L + G ++ ++GIIA +S + +GI+GV+K A YLPI+P P +R F+ Sbjct: 1818 EKANKIASILRKEGVTEESIIGIIANKSIDTIIGIVGVIKLSAVYLPIDPNLPKKRIDFI 1877 Query: 1297 LEDSGACMVLTDTAHRRSLQHGIREICLEEVAGNSGEQGNLEATASADSLAYVIYTSGST 1356 L D +VL + + IR + +EE N + + LAY++YTSGST Sbjct: 1878 LNDCKVNIVLGKGL--KEIDSNIRLLDIEERIEYEECTANPDIFKKTNLLAYIMYTSGST 1935 Query: 1357 GKPKGVMIEHRSVTNLAEALDEKIYSLHGPNLNVALLAPFVFDASVKQIFSAFLLGHHLN 1416 G PKGV++E ++V L + + + N+ + FDAS +I+ + L G L Sbjct: 1936 GVPKGVLVEQKNVIRLVKNTN----YMDFKNIRILQTGSIAFDASTFEIWGSLLNGGMLC 1991 Query: 1417 IVPGDVRQDVIQLAEYYKQNKIDISDGTPAYLRLLAETSLCARIGVAHFIIGGEALSIAE 1476 +V + + +N I+ T A+ LAE G+ H +IGG+ LS Sbjct: 1992 LVNDKEILNTESIKSNITKNCINTIWITSAFFNKLAEEKTSIFSGLRHLLIGGDTLSPKH 2051 Query: 1477 VKRFYTSFANHKPPYITNVYGPTECCVDATAFTIKPEETGQIQEMPIGAPIKNCSVYILD 1536 + K I N YGPTE +TA+ I E +PIG PI N +VYI+D Sbjct: 2052 INMVLDKCNGLK---IINGYGPTENTTFSTAYLI---EKRYYSSIPIGKPISNSNVYIVD 2105 Query: 1537 EQKRMVPRGVLGELYIGGHGVARGYCNNKALTSSRFVEDIYHPGMYMYKTGDMGKWTEDG 1596 + + P G+ GEL +GG G+A+GY N + LT+ +F+E+ + PG MY+TGD+ +W DG Sbjct: 2106 KNCNLTPIGISGELCVGGEGLAKGYLNREDLTAEKFIENPFEPGKRMYRTGDLARWLPDG 2165 Query: 1597 LIHFAGRADHQVKIRGFRIELDEIRHRLLSCDGVQAAVVLVQKDQRQEPYLCAYVVCRDE 1656 I F GR D+QVKIRGFRIEL+EI+ LL+ + V+ V+ ++D+ + Y+CAY+VC E Sbjct: 2166 NIEFLGRIDNQVKIRGFRIELNEIQSHLLTYEAVKEVAVIDREDEDKNKYICAYIVCDKE 2225 Query: 1657 QVLPGLRGYLGEYLPDYMIPRVIMPVDQIPMTANGKADTSQLPDPQEMRDHSLGYGAPRN 1716 + +RGYL LP+YM+P + ++++P+T NGK D LP+P + + Y APRN Sbjct: 2226 LTVGEIRGYLLNKLPEYMVPSYFIQIEKLPLTLNGKLDKKALPEPYRKINTGVKYEAPRN 2285 Query: 1717 RTEEILCTVWSEVLELRRIGIHDNFFAAGGDSIKAIQAAARM-EKYNLRLEVKHLFQYQT 1775 +E L ++W EVL + IG++DNFF GG S+ A +++ K + + ++ +F+ QT Sbjct: 2286 EIQEKLLSIWREVLGVENIGLNDNFFELGGHSLNATTIVSKIYSKLEVDVPLEEVFKNQT 2345 Query: 1776 IGEVSKKVQDRAGHAGYG-AVTGEAGLVPIQS-----WMVEHCRDTLQHRNLSFVLYREA 1829 I + + ++ R + GE S + ++ + N+ V+ E Sbjct: 2346 IKGIYEYIKSRERSICSSIQLIGEKEFYEASSAQKRMYTLQKLDEKSIAYNMPIVMKIEG 2405 Query: 1830 GFGEDNIRKVFTEIIRHHDALRMVFREQNRQMLQH-NRGLDGELFDFYLIDLADSPSFSE 1888 ++ + K E+I+ H+ALR F + +++Q N+ + F+ I D Sbjct: 2406 KLNKERLEKAVMELIKRHEALRTSFEIVDEKIVQKVNKAIK---FNINYIQETDKS---- 2458 Query: 1889 EXXXXXXXXXXSMDLEKGPLVKLALIRAGYGEHLLIVIHQMIIDHLSWRIILEDFNTAYT 1948 DLEK L ++A+ +LLI +H ++ D +S I++++F T Sbjct: 2459 -IDQIIKEFISPFDLEKPSLFRVAIAEIIGENYLLIDMHHIVSDGISMDILIKEF----T 2513 Query: 1949 QLLNHEDIG-LPPKTAPFLQWSNHLHEYADSIELLREQPYWDQV--ESIKAEPLPTDY 2003 L N + + L + F W N+L S + ++ YW + I +PTDY Sbjct: 2514 ALYNGKTLKPLKVQYKDFAAWQNNL---LRSEVMKSKEEYWMNRFNDEIPVLNMPTDY 2568 Score = 69.3 bits (168), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 86/402 (21%), Positives = 188/402 (46%), Gaps = 48/402 (11%) Query: 664 RYSKAEISVGQVWGAVLGMNPMSVTADFYEIGGDSIIAIEIVNTLNTIMGLSLQVPVLFE 723 R S E+ + +V+ VLG+ + + F+++GGDSI AI +++ L G L++ LF+ Sbjct: 776 RNSMEEVMI-EVFKEVLGVENLGINHSFFDLGGDSIKAIRLISKLKK-HGYKLEIKDLFK 833 Query: 724 HSNIERLAAYIEGQAGTDKDTRGNSAIPRIAAAEHYEVSSSQKRIYILNQLNARSTSYNI 783 ++ I+ ++ I + NS I + ++ QK + + ++ + +N Sbjct: 834 YNTIKDVSNRITLEE--------NSIINQELVKGKIDLIPIQKWFFEKDFID--NHHWNQ 883 Query: 784 PLFVMMEGPLDEGRLEHSFEALIQRHEVLRTSFSFVNKELVQ----------AVDDHVHL 833 + + E +E ++ F+ + + H+ LR F ++++Q +++ + Sbjct: 884 AVMLFNEEGFNESIIKKVFDKITEHHDALRIVFKNEKEDVLQFNRGLEGELYSLEVFDYR 943 Query: 834 AVEKYHADDETDLDQITSQFIRPFDLSKAPLIRAGLVEIRKNKHLLMLDVQHIIADGSSI 893 +VE Y + E +++ S +LS PL++ G+ + ++ HLL+ + H++ DG S Sbjct: 944 SVENYKKEIENKCNKLQSS----INLSNGPLVKLGMFKTKEGDHLLIF-IHHLVIDGVSW 998 Query: 894 PLLQKE--IIHLYEHNPLP----ELNIQFKDFAKWQNDLFKTDYMNKQKKYWLDVFSGEL 947 +L ++ +I+ E N P E FK+++ + + + + ++++YW ++ + + Sbjct: 999 RILLEDFSLIYNMELNNKPITLQEKTNSFKEWSTYIKEYANSKDLLQEEEYWENIENTK- 1057 Query: 948 PILNLPVDYP-RDSGQGDQGE---RLTCNAGRELTQRLNEYSSKEKTTLFMTLLAAFNVL 1003 I +P D +DS D RL+ L + +N+ + E + +T L L Sbjct: 1058 -IKKIPKDNEIKDSIFKDNRSISIRLSEEDTENLLRNVNKAYNTEINDILLTALG----L 1112 Query: 1004 LFKHTGQED-IIVGSPIAGRK----HKELEQMIGMFVNTLAL 1040 K +E+ +++ GR+ + + + IG F N L Sbjct: 1113 TIKQWSKENKVLINLEGHGREEFSSNINVSRTIGWFTNQYPL 1154 Score = 69.3 bits (168), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 86/402 (21%), Positives = 189/402 (47%), Gaps = 48/402 (11%) Query: 664 RYSKAEISVGQVWGAVLGMNPMSVTADFYEIGGDSIIAIEIVNTLNTIMGLSLQVPVLFE 723 R S E+ + +V+ VLG+ + + F+++GGDSI AI +++ L G L++ LF+ Sbjct: 3308 RNSMEEVMI-EVFKEVLGVENLGINHSFFDLGGDSIKAIRLISKLKK-HGYKLEIKDLFK 3365 Query: 724 HSNIERLAAYIEGQAGTDKDTRGNSAIPRIAAAEHYEVSSSQKRIYILNQLNARSTSYNI 783 ++ I+ ++ I + NS I + ++ QK + + ++ + +N Sbjct: 3366 YNTIKDVSNRITLEE--------NSIINQELVKGKIDLIPIQKWFFEKDFID--NHHWNQ 3415 Query: 784 PLFVMMEGPLDEGRLEHSFEALIQRHEVLRTSFSFVNKELVQ----------AVDDHVHL 833 + + E +E ++ F+ + + H+ LR F ++++Q +++ + Sbjct: 3416 AVMLFNEEGFNESIIKKVFDKITEHHDALRIVFKNEKEDVLQFNRGLEGELYSLEVFDYR 3475 Query: 834 AVEKYHADDETDLDQITSQFIRPFDLSKAPLIRAGLVEIRKNKHLLMLDVQHIIADGSSI 893 +VE Y + E +++ S +LS PL++ G+ + ++ HLL++ + H++ DG S Sbjct: 3476 SVENYKKEIENKCNKLQSS----INLSNGPLVKLGMFKTKEGDHLLIV-IHHLVIDGVSW 3530 Query: 894 PLLQKE--IIHLYEHNPLP----ELNIQFKDFAKWQNDLFKTDYMNKQKKYWLDVFSGEL 947 +L ++ +I+ E N P E FK+++ + + + + ++++YW ++ + + Sbjct: 3531 RILLEDFSLIYNMELNNKPITLQEKTNSFKEWSTYIKEYANSKDLLQEEEYWENIENTK- 3589 Query: 948 PILNLPVDYP-RDSGQGDQGE---RLTCNAGRELTQRLNEYSSKEKTTLFMTLLAAFNVL 1003 I +P D +DS D RL+ L + +N+ + E + +T L L Sbjct: 3590 -IKKVPKDNEIKDSIFKDNRSISIRLSEEDTENLLRNVNKAYNTEINDILLTALG----L 3644 Query: 1004 LFKHTGQED-IIVGSPIAGRK----HKELEQMIGMFVNTLAL 1040 K +E+ +++ GR+ + + + IG F N L Sbjct: 3645 TIKQWSKENKVLINLEGHGREEFSSNINVSRTIGWFTNQYPL 3686 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 13,418,132,105 Number of extensions: 591469501 Number of successful extensions: 1495539 Number of sequences better than 1.0e-05: 20570 Number of HSP's gapped: 1391255 Number of HSP's successfully gapped: 28155 Length of query: 2232 Length of database: 3,060,696,203 Length adjustment: 152 Effective length of query: 2080 Effective length of database: 1,628,701,923 Effective search space: 3387699999840 Effective search space used: 3387699999840 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 140 (58.5 bits)