BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0377.0013.p (358 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KC73.1 B3KC73_9BACI Phospho-2-dehydro-3-deoxyheptonate aldolase 504 e-141 C0ZHL9.1 C0ZHL9_BREBN Phospho-2-dehydro-3-deoxyheptonate aldolas... 475 e-132 Q9K7W6.1 Q9K7W6_BACHD Phospho-2-dehydro-3-deoxyheptonate aldolas... 468 e-130 Q92BA9.1 Q92BA9_LISIN 3-deoxy-D-arabino-heptulosonate 7-phosphat... 462 e-128 A0AJ50.1 A0AJ50_LISW6 Complete genome 462 e-128 >B3KC73.1 B3KC73_9BACI Phospho-2-dehydro-3-deoxyheptonate aldolase Length = 356 Score = 504 bits (1297), Expect = e-141, Method: Compositional matrix adjust. Identities = 252/356 (70%), Positives = 290/356 (81%), Gaps = 1/356 (0%) Query: 1 MSNVELEGLRARLDEINGQLLELISERAQVVQEIGAVKEKQGVPKFDPEREKQMLEKLVA 60 MS LE LR+ LD +N QLLEL+SERA++ +EIG K KQGVP FDP REK+ML+ LV Sbjct: 1 MSQGRLEQLRSELDTVNLQLLELLSERARIAKEIGQEKVKQGVPDFDPVREKKMLDTLVE 60 Query: 61 SNKGPFTSGTIRTLFKQIFSASLDLQSTDHKKSLLVARKNHAEDTVIVLPGGVTVGGPSS 120 N+GPF + T+R LFKQIF ASL LQ DHKK LLV+RK EDT+I L G +GG + Sbjct: 61 HNQGPFDNETVRHLFKQIFQASLKLQQVDHKKHLLVSRKKKQEDTLIEL-GNTVIGGGTP 119 Query: 121 LMVAGPCSVESELQTRTVAAALQKAGVKVMRGGAFKPRTSPYDFQGLGMDGLRILREPAT 180 +M+AGPCSVES Q R VAAAL++AG+ VMRGGAFKPRTSPYDFQGLG++GL+IL+E A+ Sbjct: 120 VMIAGPCSVESYEQVRQVAAALKEAGITVMRGGAFKPRTSPYDFQGLGVEGLKILKEVAS 179 Query: 181 EYGLLTISEIVDPRHIEEALDYVDVIQVGARNMHNFELLKAVGEVNKPVLLKRGLSATLD 240 E+GL TISEIVDP HIE A +Y+DVIQ+GARNM NFELLKA G+V PVLLKRGL+AT+D Sbjct: 180 EFGLKTISEIVDPAHIELACEYIDVIQIGARNMQNFELLKAAGDVQTPVLLKRGLAATID 239 Query: 241 EFVHAAEYIMSRGNMEIMLIERGIRTYEKSTRNTLDISAVPILKQECHLPVLVDVTHSTG 300 EFVHAAEYI+SRGN ++MLIERGIRTYEK+TRNTLDISAVPILKQE HLPVLVDVTHSTG Sbjct: 240 EFVHAAEYIVSRGNTQVMLIERGIRTYEKATRNTLDISAVPILKQETHLPVLVDVTHSTG 299 Query: 301 RKDILIPCXXXXXXXXXDGIMVEVHPDPATALSDAAQQLNIDEFNTFFNEVKASGL 356 RKDIL PC DG+MVEVHPDPATALSDAAQQLNI EF+ F VK SGL Sbjct: 300 RKDILAPCARAALAAGADGVMVEVHPDPATALSDAAQQLNIPEFHDFLANVKMSGL 355 >C0ZHL9.1 C0ZHL9_BREBN Phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase EC=2.5.1.54 EC=5.4.99.5 Length = 365 Score = 475 bits (1223), Expect = e-132, Method: Compositional matrix adjust. Identities = 230/358 (64%), Positives = 280/358 (78%), Gaps = 1/358 (0%) Query: 1 MSNVELEGLRARLDEINGQLLELISERAQVVQEIGAVKEKQGVPKFDPEREKQMLEKLVA 60 M++ ++E +R ++DEIN Q+LELI++RA +VQE+G KEKQG +FDPERE+QML LV Sbjct: 1 MAHDQIETMRKQIDEINLQILELINKRATLVQELGKEKEKQGSNRFDPERERQMLNLLVE 60 Query: 61 SNKGPFTSGTIRTLFKQIFSASLDLQSTDHKKSLLVARKNHAEDTVIVLPGGVTVGGPSS 120 +NKGPF IR LFKQIF SLDLQ D KK LLV+RK AEDTVI + G V GG + Sbjct: 61 NNKGPFNDNAIRHLFKQIFQVSLDLQDDDKKKVLLVSRKKKAEDTVITVKG-VEFGGKNP 119 Query: 121 LMVAGPCSVESELQTRTVAAALQKAGVKVMRGGAFKPRTSPYDFQGLGMDGLRILREPAT 180 +++AGPCSVES Q R VA K G++ +RGGA+KPRTSPYDFQGLG +GL+IL+ Sbjct: 120 ILIAGPCSVESYEQVRAVAENHAKRGLRTLRGGAYKPRTSPYDFQGLGEEGLQILKRIGD 179 Query: 181 EYGLLTISEIVDPRHIEEALDYVDVIQVGARNMHNFELLKAVGEVNKPVLLKRGLSATLD 240 E+ L+TISEIV P +E A Y+DVIQ+GARNM NFELLKA G VNKP+LLKRGLSAT++ Sbjct: 180 EFNLVTISEIVTPADLEMATKYIDVIQIGARNMQNFELLKAAGRVNKPILLKRGLSATIE 239 Query: 241 EFVHAAEYIMSRGNMEIMLIERGIRTYEKSTRNTLDISAVPILKQECHLPVLVDVTHSTG 300 EF++AAEYI+S GN ++ML ERGIRTYEK+TRNTLDISAVP+LKQE HLPV VDVTHSTG Sbjct: 240 EFIYAAEYILSEGNSQVMLCERGIRTYEKATRNTLDISAVPLLKQETHLPVFVDVTHSTG 299 Query: 301 RKDILIPCXXXXXXXXXDGIMVEVHPDPATALSDAAQQLNIDEFNTFFNEVKASGLYR 358 R+D+L+PC DGIMVEVHPDP ALSDA QQLNI +FN F +E+ ASGLY+ Sbjct: 300 RRDLLLPCAKAGFAVGSDGIMVEVHPDPDVALSDAKQQLNIPQFNEFVDELLASGLYK 357 >Q9K7W6.1 Q9K7W6_BACHD Phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase EC=2.5.1.54 Length = 364 Score = 468 bits (1203), Expect = e-130, Method: Compositional matrix adjust. Identities = 222/358 (62%), Positives = 285/358 (79%), Gaps = 1/358 (0%) Query: 1 MSNVELEGLRARLDEINGQLLELISERAQVVQEIGAVKEKQGVPKFDPEREKQMLEKLVA 60 MSN +L+ LR +LDE+N +LLELI+ERAQ+VQEIG +K KQGV +FDP RE+ ML + Sbjct: 1 MSNEQLDLLRDKLDEVNLKLLELINERAQLVQEIGQLKSKQGVNRFDPVRERNMLNHIAE 60 Query: 61 SNKGPFTSGTIRTLFKQIFSASLDLQSTDHKKSLLVARKNHAEDTVIVLPGGVTVGGPSS 120 +NKGPF + T++ +FK+IF ASL+LQ D++K+LLV+RK H E+T++ + G TVG Sbjct: 61 NNKGPFETSTLQHIFKEIFKASLELQEDDNRKALLVSRKKHPENTIVNVKGE-TVGDGEQ 119 Query: 121 LMVAGPCSVESELQTRTVAAALQKAGVKVMRGGAFKPRTSPYDFQGLGMDGLRILREPAT 180 ++ GPC+VES Q VA ++ G+K++RGGA+KPRTSPYDFQGLG++GL+IL+ A Sbjct: 120 RLIMGPCAVESYEQVAAVAKEVKARGLKLLRGGAYKPRTSPYDFQGLGLEGLKILKRVAD 179 Query: 181 EYGLLTISEIVDPRHIEEALDYVDVIQVGARNMHNFELLKAVGEVNKPVLLKRGLSATLD 240 E+ L ISEIV P +EEA+DY+DVIQ+GARNM NFELLKA G VNKPVLLKRGLSAT+ Sbjct: 180 EFDLAVISEIVTPADLEEAIDYIDVIQIGARNMQNFELLKAAGSVNKPVLLKRGLSATIS 239 Query: 241 EFVHAAEYIMSRGNMEIMLIERGIRTYEKSTRNTLDISAVPILKQECHLPVLVDVTHSTG 300 EF+HAAEYI+S+GN +IML ERGIRTYEK+TRNTLDISAVPILKQE HLPVLVDVTHSTG Sbjct: 240 EFIHAAEYIVSKGNGQIMLCERGIRTYEKATRNTLDISAVPILKQETHLPVLVDVTHSTG 299 Query: 301 RKDILIPCXXXXXXXXXDGIMVEVHPDPATALSDAAQQLNIDEFNTFFNEVKASGLYR 358 R+D+L+P D +M EVHPDPA ALSD+AQQ++I +F+ F +++ ASGLY+ Sbjct: 300 RRDLLLPTAKAALAIGADAVMAEVHPDPAVALSDSAQQMDIGQFHAFVDDLIASGLYK 357 >Q92BA9.1 Q92BA9_LISIN 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase Length = 361 Score = 462 bits (1190), Expect = e-128, Method: Compositional matrix adjust. Identities = 222/356 (62%), Positives = 277/356 (77%), Gaps = 1/356 (0%) Query: 1 MSNVELEGLRARLDEINGQLLELISERAQVVQEIGAVKEKQGVPKFDPEREKQMLEKLVA 60 M N LE LR +D++N LLELIS+RA +VQEIG +K QG +FDP RE++ML ++A Sbjct: 1 MVNTNLEELRTEVDQLNIDLLELISKRANLVQEIGKIKGTQGSLRFDPLREREMLNTILA 60 Query: 61 SNKGPFTSGTIRTLFKQIFSASLDLQSTDHKKSLLVARKNHAEDTVIVLPGGVTVGGPSS 120 +NKGPF T++ LFK+IF A L+LQ DH K+LLV+RKN EDT++ + G + +G Sbjct: 61 ANKGPFEDSTVQKLFKEIFKAGLELQEEDHSKALLVSRKNKKEDTIVTVKG-LPIGNGEP 119 Query: 121 LMVAGPCSVESELQTRTVAAALQKAGVKVMRGGAFKPRTSPYDFQGLGMDGLRILREPAT 180 + V GPCSVES Q VA +++ G+K++RGGAFKPRTSPYDFQGLG++GL+IL+ + Sbjct: 120 VFVFGPCSVESYEQVAAVAESIKAKGLKLIRGGAFKPRTSPYDFQGLGLEGLKILKRVSD 179 Query: 181 EYGLLTISEIVDPRHIEEALDYVDVIQVGARNMHNFELLKAVGEVNKPVLLKRGLSATLD 240 EYGL ISEIV P IE ALDYVDVIQ+GARNM NFELLKA G V+KP+LLKRGLSAT++ Sbjct: 180 EYGLAVISEIVTPADIEVALDYVDVIQIGARNMQNFELLKAAGRVDKPILLKRGLSATIE 239 Query: 241 EFVHAAEYIMSRGNMEIMLIERGIRTYEKSTRNTLDISAVPILKQECHLPVLVDVTHSTG 300 EF+ AAEYIMS+GN +I+L ERGIRTYEK+TRNTLDISAVPILK+E HLPV+VDVTHSTG Sbjct: 240 EFIGAAEYIMSQGNGKIILCERGIRTYEKATRNTLDISAVPILKKETHLPVMVDVTHSTG 299 Query: 301 RKDILIPCXXXXXXXXXDGIMVEVHPDPATALSDAAQQLNIDEFNTFFNEVKASGL 356 RKD+L+PC DG+M EVHPDPA ALSD+AQQ++I EF F+N + AS L Sbjct: 300 RKDLLLPCAKAALAIEADGVMAEVHPDPAVALSDSAQQMDIPEFEEFWNAILASNL 355 >A0AJ50.1 A0AJ50_LISW6 Complete genome Length = 361 Score = 462 bits (1190), Expect = e-128, Method: Compositional matrix adjust. Identities = 222/356 (62%), Positives = 277/356 (77%), Gaps = 1/356 (0%) Query: 1 MSNVELEGLRARLDEINGQLLELISERAQVVQEIGAVKEKQGVPKFDPEREKQMLEKLVA 60 M N LE LR +D++N LLELIS+RA +VQEIG +K QG +FDP RE++ML ++A Sbjct: 1 MVNTNLEELRTEVDQLNIDLLELISKRANLVQEIGKIKGTQGSLRFDPLREREMLNTILA 60 Query: 61 SNKGPFTSGTIRTLFKQIFSASLDLQSTDHKKSLLVARKNHAEDTVIVLPGGVTVGGPSS 120 +N+GPF T++ LFK+IF A L+LQ DH K+LLV+RKN EDT++ + G V +G Sbjct: 61 ANEGPFEDSTVQKLFKEIFKAGLELQEEDHSKALLVSRKNKQEDTIVTVKG-VPIGNGEP 119 Query: 121 LMVAGPCSVESELQTRTVAAALQKAGVKVMRGGAFKPRTSPYDFQGLGMDGLRILREPAT 180 + V GPCSVES Q VA +++ G+K++RGGAFKPRTSPYDFQGLG++GL+IL+ + Sbjct: 120 VFVFGPCSVESYEQVAAVAESIKAKGLKLIRGGAFKPRTSPYDFQGLGLEGLKILKRVSD 179 Query: 181 EYGLLTISEIVDPRHIEEALDYVDVIQVGARNMHNFELLKAVGEVNKPVLLKRGLSATLD 240 EYGL ISEIV P IE ALDYVDVIQ+GARNM NFELLKA G V+KP+LLKRGLSAT++ Sbjct: 180 EYGLAVISEIVTPADIEVALDYVDVIQIGARNMQNFELLKAAGRVDKPILLKRGLSATIE 239 Query: 241 EFVHAAEYIMSRGNMEIMLIERGIRTYEKSTRNTLDISAVPILKQECHLPVLVDVTHSTG 300 EF+ AAEYIMS+GN +I+L ERGIRTYEK+TRNTLDISAVPILK+E HLPV+VDVTHSTG Sbjct: 240 EFIGAAEYIMSQGNGKIILCERGIRTYEKATRNTLDISAVPILKKETHLPVMVDVTHSTG 299 Query: 301 RKDILIPCXXXXXXXXXDGIMVEVHPDPATALSDAAQQLNIDEFNTFFNEVKASGL 356 RKD+L+PC DG+M EVHPDPA ALSD+AQQ++I EF F+N + AS L Sbjct: 300 RKDLLLPCAKAALAIEADGVMAEVHPDPAVALSDSAQQMDIPEFEEFWNAILASNL 355 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.135 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,931,957,491 Number of extensions: 76068086 Number of successful extensions: 277732 Number of sequences better than 1.0e-05: 1835 Number of HSP's gapped: 276196 Number of HSP's successfully gapped: 1836 Length of query: 358 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 221 Effective length of database: 1,770,017,148 Effective search space: 391173789708 Effective search space used: 391173789708 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 132 (55.5 bits)