BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0373.0011.p (301 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KH04.1 B3KH04_9BACI Oxidoreductase domain protein 271 8e-71 B7R6B3.1 B7R6B3_9THEO Oxidoreductase family, NAD-binding Rossman... 262 3e-68 A6PS58.1 A6PS58_9BACT Oxidoreductase domain protein 209 2e-52 C1Z143.1 C1Z143_PEDHE Predicted dehydrogenase 207 9e-52 C4D2B5.1 C4D2B5_9SPHI Predicted dehydrogenase 206 2e-51 >B3KH04.1 B3KH04_9BACI Oxidoreductase domain protein Length = 305 Score = 271 bits (692), Expect = 8e-71, Method: Compositional matrix adjust. Identities = 144/298 (48%), Positives = 184/298 (61%), Gaps = 2/298 (0%) Query: 4 LKIGMVGMDTSHSRIFAAMLNHVSHPLHVPGGRLIWGYAGGSADFALSASRVGAISRELQ 63 +KIGM+G+DTSH IFA ML+ +HP HVPG R+ + GGS DF LS +RV ++EL Sbjct: 3 MKIGMIGLDTSHVSIFAKMLHDKAHPYHVPGARVTAAFPGGSPDFELSINRVEGYTKELA 62 Query: 64 ENCGVELLDSIAEVAEKSDAVLLTSVDGRVHREQFAILAPYGKPVFIDKPFAVTSADALA 123 G E+L+S +VA++ DAV+L +VDGR H F +APY K VFIDKPFAV+S DA Sbjct: 63 A-WGTEILESPEDVAKQVDAVMLEAVDGRSHLSLFRAIAPYCKQVFIDKPFAVSSKDARE 121 Query: 124 IVDLAASCGTPLFSSSVVRFGSPLNAALQDETEGAIVGADCSGPLELQPTQPGLFWYGIH 183 I +LA + S S +R+ L L I+G DC+GPL LQPTQPG FWYGIH Sbjct: 122 IAELAEQYQVTVMSCSSLRYAQGLQDELARGGADNIIGVDCAGPLPLQPTQPGFFWYGIH 181 Query: 184 TAEMLYAALGEGCISVRAISNEIQEWAVGLWKGGRIGTMRGNRTGGADFYAVLHRERGST 243 AEMLY LG GC+SV + E+ E +W G IGT+RGNR G F +HR ST Sbjct: 182 AAEMLYRVLGPGCVSVHVAATELHEVLTAVWNDGTIGTIRGNRAGNDRFGLTVHRAEAST 241 Query: 244 AVNALGGHYEAGHHSLLKQFLLMARGAPPPVSPTVTLELIRFLEAANESRETGQTVFL 301 V+ + H + + SLL Q + M V + TLE++RFLEAAN SR TG+ V L Sbjct: 242 FVDIM-EHPKPYYASLLDQIMKMFTTGVSDVPLSETLEIVRFLEAANVSRVTGENVRL 298 >B7R6B3.1 B7R6B3_9THEO Oxidoreductase family, NAD-binding Rossmann fold protein Length = 291 Score = 262 bits (670), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 129/293 (44%), Positives = 186/293 (63%), Gaps = 5/293 (1%) Query: 4 LKIGMVGMDTSHSRIFAAMLNHVSHPLHVPGGRLIWGYAGGSADFALSASRVGAISRELQ 63 L+IG++G+D+SH+ F +LN+ +P HV GG+++ Y GGS DF LS SRV ++ L+ Sbjct: 2 LRIGIIGLDSSHAVEFTELLNNDHNPYHVKGGKVVIAYPGGSKDFDLSISRVWEYTKILK 61 Query: 64 ENCGVELLDSIAEVAEKSDAVLLTSVDGRVHREQFAILAPYGKPVFIDKPFAVTSADALA 123 E GV+++DS EVAE SD +L+ S DGRVH EQF+ + Y KPVFIDKP +++ + Sbjct: 62 EKYGVQIVDSPEEVAENSDGILIESADGRVHFEQFSKIVSYKKPVFIDKPMSLSFKETSK 121 Query: 124 IVDLAASCGTPLFSSSVVRFGSPLNAALQDETEGAIVGADCSGPLELQPTQPGLFWYGIH 183 + +A G PL SSS +R+ L L + I+G D GP+ LQPTQPGLFWYGIH Sbjct: 122 MFGIAEKYGIPLMSSSALRYAEGLCKTLSSINKEDIIGVDVYGPMPLQPTQPGLFWYGIH 181 Query: 184 TAEMLYAALGEGCISVRAISNEIQEWAVGLWKGGRIGTMRGNRTGGADFYAVLHRERGST 243 E+L+ LG V+AI+NE + VG+W+ GRIGT+RGNR G +F A++H ++ + Sbjct: 182 MVEILFTILGRNFKCVKAINNEDHDLVVGVWEDGRIGTVRGNRKGNNNFGALIHLQKYTK 241 Query: 244 AV--NALGGHYEAGHHSLLKQFLLMARGAPPPVSPTVTLELIRFLEAANESRE 294 V NA Y A S+L++ + M P+ P T ++IRF+E AN+ R+ Sbjct: 242 FVDINAFPKPYYA---SILEKIMEMFVKGIAPIEPDETKQIIRFIEIANQYRQ 291 >A6PS58.1 A6PS58_9BACT Oxidoreductase domain protein Length = 300 Score = 209 bits (533), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 123/299 (41%), Positives = 173/299 (57%), Gaps = 11/299 (3%) Query: 1 LKELKIGMVGMDTSHSRIFAAMLNHVSHPLHVPGGRLIWGYAGGSADFALSASRVGAISR 60 ++ELK+G+VG+DTSH FA N + HVPG +++ + GGS F+LS SRV + Sbjct: 1 MQELKVGLVGLDTSHVVCFAGCFNDPADQFHVPGVKVVKAFPGGSETFSLSRSRVAGFTA 60 Query: 61 ELQENCGVELLDSIAEVAEKSDAVLLTSVDGRVHREQFAILAPYGKPVFIDKPFAVTSAD 120 +L++ GVE++ SI E+A DA LL SVDG H EQF +LA +GKPVFIDKP A + +D Sbjct: 61 DLRDKYGVEIVSSIEELA-GLDAYLLESVDGAQHLEQFKVLAKFGKPVFIDKPLACSYSD 119 Query: 121 ALAIVDLAASCGTPLFSSSVVRFGSPLNAAL--QDETEGAIVGADCSGPLELQPTQPGLF 178 A + DLAA P+ ++S +RF + + A L QDET + A+ GP+ + F Sbjct: 120 ARTLFDLAAQYNVPIMTASSMRFAAGI-AGLKPQDET---VAAAEGFGPMAILDDYRDYF 175 Query: 179 WYGIHTAEMLYAALGEGCISVRAISNEIQEWAVGLWKGGRIGTMRGNRTGGADFYAVLHR 238 WYGIH+AE++Y+ LG+GC V SN + VG W GR+G + GNR G +F L Sbjct: 176 WYGIHSAEIVYSYLGKGCAEVHTESNGKFDLVVGRWNDGRLGLVAGNRVGANNFGVRLTT 235 Query: 239 E-RGSTAVNALGGHYEAGHHSLLKQFLLMARGAPPPVSPTVTLELIRFLEAANESRETG 296 + R +V Y + +F R P+ P +LE+I FLEAA+ SR G Sbjct: 236 DKRHIVSVQNPDIPYMFALAQSIDRFF---RTGVSPIDPAESLEVIAFLEAASRSRARG 291 >C1Z143.1 C1Z143_PEDHE Predicted dehydrogenase Length = 327 Score = 207 bits (527), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 112/292 (38%), Positives = 172/292 (58%), Gaps = 7/292 (2%) Query: 5 KIGMVGMDTSHSRIFAAMLNHVSHPLHVPGGRLIWGYAGGSADFALSASRVGAISRELQE 64 ++G++G+DTSH+ F LN P G +++ Y GS D A S R+ I+ E++ Sbjct: 29 RVGIIGLDTSHAVAFTKTLNAADAPASYGGYKVVAAYPKGSNDIASSVERIPGITAEVK- 87 Query: 65 NCGVELLDSIAEVAEKSDAVLLTSVDGRVHREQFAILAPYGKPVFIDKPFAVTSADALAI 124 N GVE+++SIA++ +K D VLL + DGR+H EQ + KP+FIDKP A + ADA AI Sbjct: 88 NMGVEIVNSIADLLKKVDVVLLETNDGRLHLEQATEVLKARKPMFIDKPMAASLADATAI 147 Query: 125 VDLAASCGTPLFSSSVVRFGSPLNAALQDETEGAIVGADCSGPLELQPTQPGLFWYGIHT 184 LA TP+FSSS +R+ + A + + G ++GA+ P +L+ T P FWYGIH Sbjct: 148 FALAKKYNTPVFSSSSLRYIDGI-AEINEGKIGKVLGAETYSPSKLEKTHPDFFWYGIHG 206 Query: 185 AEMLYAALGEGCISVRAISNEIQEWAVGLWKGGRIGTMRGNRTGGADFYAVLHRERGSTA 244 EML+ +G GC +V I + VG+W+ GRIG+ RG R G + + + E+ + A Sbjct: 207 IEMLFTIMGTGCKTVTRIHTPDTDVVVGVWEDGRIGSFRGTRKGASSYGGRVFGEKATVA 266 Query: 245 VNALGGHYEAGHHSLLKQFLLMARGAPPPVSPTVTLELIRFLEAANESRETG 296 + G+++ G++ LL++ + PV P TLE+ F+EAA+ES+ G Sbjct: 267 L----GNFK-GYNPLLEEIVKFFESGQSPVRPEETLEIAAFMEAADESKAKG 313 >C4D2B5.1 C4D2B5_9SPHI Predicted dehydrogenase Length = 340 Score = 206 bits (524), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 116/292 (39%), Positives = 166/292 (56%), Gaps = 7/292 (2%) Query: 5 KIGMVGMDTSHSRIFAAMLNHVSHPLHVPGGRLIWGYAGGSADFALSASRVGAISRELQE 64 ++G++G+DTSHS F +LN + + G ++ Y GS D S RV + E+++ Sbjct: 36 RVGIIGLDTSHSTAFTKLLNDPNSGPDLAGFTVVAAYPQGSPDIESSTKRVPGYTEEVKK 95 Query: 65 NCGVELLDSIAEVAEKSDAVLLTSVDGRVHREQFAILAPYGKPVFIDKPFAVTSADALAI 124 GVE++ SI ++ +K D VLL + DGR H EQ ++ GK +FIDKP A T +DA+ I Sbjct: 96 -MGVEIVSSIPDLLKKVDVVLLETNDGRPHLEQAMLVLKAGKRLFIDKPVAGTLSDAMTI 154 Query: 125 VDLAASCGTPLFSSSVVRFGSPLNAALQDETEGAIVGADCSGPLELQPTQPGLFWYGIHT 184 A G P+FS+S +R+ + A + GA++GAD P L+ T P LFWYGIH Sbjct: 155 FTQAKRAGVPIFSASSLRYSASAQAVAKGSI-GAVLGADAFSPAHLEKTHPDLFWYGIHG 213 Query: 185 AEMLYAALGEGCISVRAISNEIQEWAVGLWKGGRIGTMRGNRTGGADFYAVLHRERGSTA 244 E LY A+G GC V + + + VG W GRIGT RG RTG ++ + E+G Sbjct: 214 VETLYTAMGTGCKQVVRVQTDGTDVVVGTWADGRIGTFRGTRTGKNEYGGTAYGEKG--- 270 Query: 245 VNALGGHYEAGHHSLLKQFLLMARGAPPPVSPTVTLELIRFLEAANESRETG 296 NA G Y+ G+ LL Q + + PPVS TLE+ F+EAA+ES+ G Sbjct: 271 -NAPLGPYD-GYRPLLVQIIEFFKTGMPPVSAEETLEIYTFMEAADESKRLG 320 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,827,695,107 Number of extensions: 76250420 Number of successful extensions: 179673 Number of sequences better than 1.0e-05: 28 Number of HSP's gapped: 179638 Number of HSP's successfully gapped: 28 Length of query: 301 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 166 Effective length of database: 1,788,859,178 Effective search space: 296950623548 Effective search space used: 296950623548 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 131 (55.1 bits)