BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0370.0037.p (327 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KE61.1 B3KE61_9BACI Ku protein 468 e-130 B1D5P6.1 B1D5P6_9BACL Ku protein 395 e-108 C0ZFQ9.1 C0ZFQ9_BREBN YkoV protein 307 8e-82 B8I5T2.1 B8I5T2_CLOCE Ku protein 293 1e-77 Q8EM28.1 Q8EM28_OCEIH Hypothetical conserved protein 286 2e-75 >B3KE61.1 B3KE61_9BACI Ku protein Length = 309 Score = 468 bits (1203), Expect = e-130, Method: Compositional matrix adjust. Identities = 230/317 (72%), Positives = 255/317 (80%), Gaps = 13/317 (4%) Query: 8 MHTVWKGAISFGLVHVPVKMFSATEDKDISLRYIHKECGSPLSYVRKCPVCDKEVAWEEI 67 MHTVWKGAISFGLVHVPVKMFSATEDKDIS+RYIHKECGSPLSY+RKCPVC++EVAWEEI Sbjct: 1 MHTVWKGAISFGLVHVPVKMFSATEDKDISMRYIHKECGSPLSYIRKCPVCEEEVAWEEI 60 Query: 68 GKGYEYDKGKFVLFEKEELEQLTEQSTKNIAILDFVDLTEIDPIYFQKTYYLSPDQAGAN 127 KGYEY+KGKFVLFEKEELEQL E ++KNI ILDFVDLTEIDPIYFQKTYYLSPDQAGAN Sbjct: 61 TKGYEYEKGKFVLFEKEELEQLAEANSKNITILDFVDLTEIDPIYFQKTYYLSPDQAGAN 120 Query: 128 AYRLLMEAMRQTGKIGIAKISIRSKSSLAAIRVLADCLAIETIFYPDEVRPVSQVPGLPE 187 AYRLL+EAM+Q+GKIGIAKI+IRSKSSLAAIRVL +CL+IETIFYPDE+RP+SQVP LPE Sbjct: 121 AYRLLLEAMKQSGKIGIAKIAIRSKSSLAAIRVLDECLSIETIFYPDEIRPISQVPNLPE 180 Query: 188 PGIVNDKELDMAKLLISQLSTPFEPGKYTDDYRQRMLDLITHKIAGEEFHIAPARQESNV 247 VN KELDMAKLLI QLSTPF+P KYTDDYR+R+LDLI K++GEE IAPARQE+NV Sbjct: 181 RTEVNAKELDMAKLLIDQLSTPFDPEKYTDDYRERLLDLINSKVSGEEIKIAPARQETNV 240 Query: 248 IDLMAALQASIEAVQHIPADPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVVSEATGP 307 +DLMAALQASIEAV+ I DP + G Sbjct: 241 VDLMAALQASIEAVKPIGTDPGTKPKPRKTTRKTAAKEPAAKV-------------SGGE 287 Query: 308 IPVIAPKPKRRTAKSKE 324 APKPKRR KSK+ Sbjct: 288 ADADAPKPKRRATKSKK 304 >B1D5P6.1 B1D5P6_9BACL Ku protein Length = 301 Score = 395 bits (1015), Expect = e-108, Method: Compositional matrix adjust. Identities = 182/259 (70%), Positives = 219/259 (84%) Query: 8 MHTVWKGAISFGLVHVPVKMFSATEDKDISLRYIHKECGSPLSYVRKCPVCDKEVAWEEI 67 MHTVWKGAISFGLVHVPVKMF+ATEDKDISLR IHK CGSP++YVR+CP CD E W++I Sbjct: 1 MHTVWKGAISFGLVHVPVKMFTATEDKDISLRMIHKPCGSPIAYVRRCPNCDVEAEWDDI 60 Query: 68 GKGYEYDKGKFVLFEKEELEQLTEQSTKNIAILDFVDLTEIDPIYFQKTYYLSPDQAGAN 127 KGYEY+KG +VLFEK+ELEQL + + I ILDFV L EIDP+YFQKTYYLSPDQAG+N Sbjct: 61 IKGYEYEKGSYVLFEKDELEQLAGEKSHTIQILDFVALEEIDPVYFQKTYYLSPDQAGSN 120 Query: 128 AYRLLMEAMRQTGKIGIAKISIRSKSSLAAIRVLADCLAIETIFYPDEVRPVSQVPGLPE 187 AY LL++AM TGKIG+AK+SIRSKSSLAAIRV+ +CLA+ETIFYPDE+R +S VPG+PE Sbjct: 121 AYGLLLQAMSDTGKIGVAKVSIRSKSSLAAIRVIDNCLAMETIFYPDEIRSISHVPGIPE 180 Query: 188 PGIVNDKELDMAKLLISQLSTPFEPGKYTDDYRQRMLDLITHKIAGEEFHIAPARQESNV 247 +NDKEL MAKLLI QLSTPFEP KY+DDYR ML I +K+AG+E +AP ++++NV Sbjct: 181 SFTINDKELTMAKLLIEQLSTPFEPSKYSDDYRANMLQAIQNKVAGQEIRVAPQQEQTNV 240 Query: 248 IDLMAALQASIEAVQHIPA 266 +DLMAALQAS++A + P Sbjct: 241 LDLMAALQASLDAAKLPPG 259 >C0ZFQ9.1 C0ZFQ9_BREBN YkoV protein Length = 319 Score = 307 bits (787), Expect = 8e-82, Method: Compositional matrix adjust. Identities = 138/262 (52%), Positives = 191/262 (72%), Gaps = 1/262 (0%) Query: 8 MHTVWKGAISFGLVHVPVKMFSATEDKDISLRYIHKECGSPLSYVRKCPVCDKEVAWEEI 67 MHTVWKG+ISFGLV++PV+MF+ATE++DI R +HKEC +P+ Y + CP C +EV EI Sbjct: 1 MHTVWKGSISFGLVNIPVRMFTATEERDIRFRQLHKECNTPIKYTKMCPHCQREVDTSEI 60 Query: 68 GKGYEYDKGKFVLFEKEELEQLTEQSTKNIAILDFVDLTEIDPIYFQKTYYLSPDQAGAN 127 +G+EY+KG FV+ + ++LE +T ++ + I I+DFVDL+E+DP+YF K+Y+LSP G Sbjct: 61 VRGFEYEKGHFVMIDDDDLEAITPETRRAIEIIDFVDLSEVDPVYFHKSYFLSPQDTGEK 120 Query: 128 AYRLLMEAMRQTGKIGIAKISIRSKSSLAAIRVLADCLAIETIFYPDEVRPVSQVPGLPE 187 AY LL AM QTGKIG+A++++R++ SLA IR+ C+ +ETIFYPDEVRPVSQVP LPE Sbjct: 121 AYALLRSAMEQTGKIGVAQVTMRNRQSLAVIRLYEHCIMLETIFYPDEVRPVSQVPALPE 180 Query: 188 PGI-VNDKELDMAKLLISQLSTPFEPGKYTDDYRQRMLDLITHKIAGEEFHIAPARQESN 246 + + + EL MA LIS ++ PF+P KYTD+YR + LI K+ G+E AP +N Sbjct: 181 ATVQLAENELKMATELISNMTIPFDPAKYTDEYRSDLQKLIEKKLEGQEIATAPTVARTN 240 Query: 247 VIDLMAALQASIEAVQHIPADP 268 VIDLM AL+ S+E+ A P Sbjct: 241 VIDLMQALKESLESTAGQAAMP 262 >B8I5T2.1 B8I5T2_CLOCE Ku protein Length = 312 Score = 293 bits (751), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 134/252 (53%), Positives = 181/252 (71%) Query: 8 MHTVWKGAISFGLVHVPVKMFSATEDKDISLRYIHKECGSPLSYVRKCPVCDKEVAWEEI 67 MHTVWKG+ISFGLV++PVKMF+ATEDKDI +YIHKEC SP+ Y + CPVC+KEV E+I Sbjct: 1 MHTVWKGSISFGLVNIPVKMFTATEDKDIRFKYIHKECHSPVKYKKVCPVCNKEVQPEDI 60 Query: 68 GKGYEYDKGKFVLFEKEELEQLTEQSTKNIAILDFVDLTEIDPIYFQKTYYLSPDQAGAN 127 +G+EY+ GK+V+ E+ E L +S K + I+DFV L E+DP+YF KTY+L+P + G Sbjct: 61 VRGFEYEPGKYVIMTGEDFESLQVKSEKTVEIIDFVKLEEVDPVYFDKTYFLAPQETGGK 120 Query: 128 AYRLLMEAMRQTGKIGIAKISIRSKSSLAAIRVLADCLAIETIFYPDEVRPVSQVPGLPE 187 AY LL EA+ Q KI ++KI+IR + SLA IRV + L +ETIFYPDEV+ +QVPG+PE Sbjct: 121 AYTLLREALGQKEKIAVSKITIRDRESLAVIRVYKNVLVLETIFYPDEVKDSAQVPGIPE 180 Query: 188 PGIVNDKELDMAKLLISQLSTPFEPGKYTDDYRQRMLDLITHKIAGEEFHIAPARQESNV 247 ELDMA LI L+T F+P KY D YR+++++LI K+ G++ ++ NV Sbjct: 181 ATKTTPAELDMATQLIDNLTTAFDPSKYVDTYREKLVELINAKVEGKQVVARKEVEKENV 240 Query: 248 IDLMAALQASIE 259 + LM ALQ SI+ Sbjct: 241 VSLMEALQRSIQ 252 >Q8EM28.1 Q8EM28_OCEIH Hypothetical conserved protein Length = 280 Score = 286 bits (732), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 141/255 (55%), Positives = 181/255 (70%), Gaps = 3/255 (1%) Query: 8 MHTVWKGAISFGLVHVPVKMFSATEDKDISLRYIHKECGSPLSYVRKCPVCDKEVAWEEI 67 MHT+WKG ISFGLV++PVKM +ATE+KDI LR +HK+C +P+ Y + CP C+++V+ ++I Sbjct: 1 MHTMWKGTISFGLVNIPVKMHAATENKDIRLRQLHKKCKTPIKYEKVCPNCEEDVSNDDI 60 Query: 68 GKGYEYDKGKFVLFEKEELEQLT-EQSTKNIAILDFVDLTEIDPIYFQKTYYLSPDQAGA 126 K YEY K KFV+ + EELE L EQ K + I+DFV L +IDPIYF+K+YYLSP++ G+ Sbjct: 61 VKAYEYAKNKFVVLDDEELEALKKEQEDKAVEIIDFVQLKDIDPIYFEKSYYLSPNEGGS 120 Query: 127 NAYRLLMEAMRQTGKIGIAKISIRSKSSLAAIRVLADCLAIETIFYPDEVRPVSQVPGLP 186 AY LL EA+ +GKIGIAK+ IRSK LA IRV + +ETI YPDEVR VS VP +P Sbjct: 121 KAYALLREALLDSGKIGIAKMMIRSKEQLAVIRVYESAIVVETIHYPDEVRAVSDVPNVP 180 Query: 187 EPGIVNDKELDMAKLLISQLSTPFEPGKYTDDYRQRMLDLITHKIAGEEFHIA--PARQE 244 E V KELD AKLLI QL+T FEP KY D+YR +L+LI K EE + P Sbjct: 181 EQADVGKKELDTAKLLIDQLTTEFEPEKYQDNYRTALLELIEAKKNNEEIEVGGEPKSTP 240 Query: 245 SNVIDLMAALQASIE 259 NV +LM ALQ S++ Sbjct: 241 DNVTNLMDALQESLD 255 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,700,945,113 Number of extensions: 64619747 Number of successful extensions: 158222 Number of sequences better than 1.0e-05: 416 Number of HSP's gapped: 157329 Number of HSP's successfully gapped: 416 Length of query: 327 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 191 Effective length of database: 1,779,438,163 Effective search space: 339872689133 Effective search space used: 339872689133 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)