BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0370.0031.p (349 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KE55.1 B3KE55_9BACI Metalloendopeptidase, glycoprotease family... 462 e-128 B1DH39.1 B1DH39_9BACL Metalloendopeptidase, glycoprotease family... 435 e-120 C0ZK41.1 C0ZK41_BREBN O-sialoglycoprotein endopeptidase EC=3.4.2... 374 e-102 A9VQG1.1 A9VQG1_BACWK Putative metalloendopeptidase, glycoprotea... 363 1e-98 C2SEJ3.1 C2SEJ3_BACCE O-sialoglycoprotein endopeptidase 363 1e-98 >B3KE55.1 B3KE55_9BACI Metalloendopeptidase, glycoprotease family EC=3.4.24.57 Length = 347 Score = 462 bits (1188), Expect = e-128, Method: Compositional matrix adjust. Identities = 234/345 (67%), Positives = 260/345 (75%) Query: 1 MKTETGEVQPVLILAIETSCDETSVAVVKDGCEVLSNMISSQIETHRAFGGVVPEVASRK 60 MK E + Q ILAIETSCDETSVAVVKDGCEVLS++I+SQIETH+AFGGVVPEVASRK Sbjct: 1 MKDEKIDRQHSCILAIETSCDETSVAVVKDGCEVLSSVIASQIETHKAFGGVVPEVASRK 60 Query: 61 HVEVITLVIEGALKAAGVQPEQLTAVAVTQXXXXXXXXXXXXXXXXXXXXXWGKPLIGTH 120 HVE ITL+IE A+ AG++ + L+A+AVTQ GKPLIGTH Sbjct: 61 HVESITLIIEQAVAEAGIEMKDLSAIAVTQGPGLVGALLVGVMAAKSLAFALGKPLIGTH 120 Query: 121 HIAGHIYANRLVKELQYPNMTLVVSGGHTELVSMEREGKFRIIGRTRDDAVGEAYDKVAR 180 HIAGHIYANR V ++ YP M LVVSGGHTELV M+ EG F +IGRTRDDAVGEAYDKVAR Sbjct: 121 HIAGHIYANRFVGDIAYPCMALVVSGGHTELVYMKEEGSFELIGRTRDDAVGEAYDKVAR 180 Query: 181 ALGFPYPGGPHVDXXXXXXXXXXXXXXXWLEPDSYDFSFSGLKSAVLNVVNQSKMKGLAP 240 ALGFPYPGGPHVD WLEPDSYDFSFSGLKSAVLNVVNQSKM+G Sbjct: 181 ALGFPYPGGPHVDRMALEAEEVVDLPRVWLEPDSYDFSFSGLKSAVLNVVNQSKMRGEDV 240 Query: 241 DVAGIARGFQESVVEVLVEKAVRAVKATQAKQLLLSGGVAANKGLREALTARCEAEGIEL 300 IARGFQESVVEVLVEKAVRAVKA AKQLLL GGVAAN+GLR+AL+ RC EGI L Sbjct: 241 RTEAIARGFQESVVEVLVEKAVRAVKAYDAKQLLLCGGVAANRGLRQALSERCGQEGIPL 300 Query: 301 IIPPPVFCTDNAAMIGAAAYVKWRHDGSTPLDMVADPGFSLENWS 345 IPP +CTDN AMI AAA++KW+ + TPLDM ADP SLE W+ Sbjct: 301 TIPPFQYCTDNGAMIAAAAHLKWKRESFTPLDMKADPQMSLEYWA 345 >B1DH39.1 B1DH39_9BACL Metalloendopeptidase, glycoprotease family EC=3.4.24.57 Length = 347 Score = 435 bits (1119), Expect = e-120, Method: Compositional matrix adjust. Identities = 216/337 (64%), Positives = 250/337 (74%) Query: 9 QPVLILAIETSCDETSVAVVKDGCEVLSNMISSQIETHRAFGGVVPEVASRKHVEVITLV 68 Q +ILAIETSCDETSVAVV+ G +LSN+ISSQIE H+ FGGVVPE+ASRKHVEVITL+ Sbjct: 7 QDAVILAIETSCDETSVAVVRGGKHILSNVISSQIEVHKQFGGVVPEIASRKHVEVITLM 66 Query: 69 IEGALKAAGVQPEQLTAVAVTQXXXXXXXXXXXXXXXXXXXXXWGKPLIGTHHIAGHIYA 128 IE A++ +G+ ++AVAVTQ P IGTHHIAGHIYA Sbjct: 67 IEQAIEESGLTLRDISAVAVTQGPGLVGALLVGIVAAKSLAMALDVPFIGTHHIAGHIYA 126 Query: 129 NRLVKELQYPNMTLVVSGGHTELVSMEREGKFRIIGRTRDDAVGEAYDKVARALGFPYPG 188 N+LV EL+YP M LVVSGGHTELV +E EG FR+IGRTRDDAVGEAYDKVARAL FPYPG Sbjct: 127 NQLVHELEYPCMALVVSGGHTELVLLESEGSFRMIGRTRDDAVGEAYDKVARALKFPYPG 186 Query: 189 GPHVDXXXXXXXXXXXXXXXWLEPDSYDFSFSGLKSAVLNVVNQSKMKGLAPDVAGIARG 248 GPH+D WLEPDSYDFSFSGLKSAVL V+NQ+ MKG D +ARG Sbjct: 187 GPHIDRLASEAEAVIELPRAWLEPDSYDFSFSGLKSAVLAVINQTNMKGETLDAGALARG 246 Query: 249 FQESVVEVLVEKAVRAVKATQAKQLLLSGGVAANKGLREALTARCEAEGIELIIPPPVFC 308 FQESV EVLVEKA+RAV+A AKQLLL GGVAANKGLR AL +RC+ +G+ L++PP C Sbjct: 247 FQESVTEVLVEKALRAVRAFGAKQLLLCGGVAANKGLRAALASRCDKDGVPLLVPPHKLC 306 Query: 309 TDNAAMIGAAAYVKWRHDGSTPLDMVADPGFSLENWS 345 TDNAAMIGAAA++KW+ T LDM A+P FSLE W+ Sbjct: 307 TDNAAMIGAAAFLKWQKGEFTSLDMKAEPNFSLEGWA 343 >C0ZK41.1 C0ZK41_BREBN O-sialoglycoprotein endopeptidase EC=3.4.24.57 Length = 360 Score = 374 bits (960), Expect = e-102, Method: Compositional matrix adjust. Identities = 189/332 (56%), Positives = 227/332 (68%) Query: 10 PVLILAIETSCDETSVAVVKDGCEVLSNMISSQIETHRAFGGVVPEVASRKHVEVITLVI 69 P IL IETSCDETS +V++DG EVLSN+I+SQ + H+ FGGVVPEVASR+HVE ITL I Sbjct: 26 PTYILGIETSCDETSASVIRDGREVLSNVIASQADIHKRFGGVVPEVASRRHVENITLTI 85 Query: 70 EGALKAAGVQPEQLTAVAVTQXXXXXXXXXXXXXXXXXXXXXWGKPLIGTHHIAGHIYAN 129 E AL AG + + A+AVT G PLIG HHIAGHIYAN Sbjct: 86 EEALTEAGKTLDDIQAIAVTYGPGLVGALLVGVAAAKAISMARGIPLIGVHHIAGHIYAN 145 Query: 130 RLVKELQYPNMTLVVSGGHTELVSMEREGKFRIIGRTRDDAVGEAYDKVARALGFPYPGG 189 RLV+E+++P + LVVSGGHTELV M+ G+F I+G TRDDA GEAYDKVARAL PYPGG Sbjct: 146 RLVQEMEFPLIALVVSGGHTELVWMKEHGQFEILGETRDDAAGEAYDKVARALNMPYPGG 205 Query: 190 PHVDXXXXXXXXXXXXXXXWLEPDSYDFSFSGLKSAVLNVVNQSKMKGLAPDVAGIARGF 249 PH+D WL PDSYDFSFSGLKSAVLN ++ + +G + A +A F Sbjct: 206 PHIDRLAHEGEANVPLPRSWLAPDSYDFSFSGLKSAVLNTLHNAAQRGETIEPANLAASF 265 Query: 250 QESVVEVLVEKAVRAVKATQAKQLLLSGGVAANKGLREALTARCEAEGIELIIPPPVFCT 309 Q+SV EVLVEK +RA ++ AKQ+LL+GGVAAN+GLRE L ARCEAEGI L+IPP CT Sbjct: 266 QDSVTEVLVEKTIRAARSHGAKQVLLAGGVAANRGLRERLQARCEAEGIPLVIPPFSLCT 325 Query: 310 DNAAMIGAAAYVKWRHDGSTPLDMVADPGFSL 341 DNAAMI AA ++K+ LD+ P SL Sbjct: 326 DNAAMIAAAGFIKYEKGQFEGLDLNGVPSLSL 357 >A9VQG1.1 A9VQG1_BACWK Putative metalloendopeptidase, glycoprotease family EC=3.4.24.57 Length = 338 Score = 363 bits (933), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 183/333 (54%), Positives = 226/333 (67%), Gaps = 1/333 (0%) Query: 11 VLILAIETSCDETSVAVVKDGCEVLSNMISSQIETHRAFGGVVPEVASRKHVEVITLVIE 70 ++IL IETSCDET+VAVVK+G E+++N+++SQIE+H+ FGGVVPE+ASR HVE IT+V+E Sbjct: 5 IIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLE 64 Query: 71 GALKAAGVQPEQLTAVAVTQXXXXXXXXXXXXXXXXXXXXXWGKPLIGTHHIAGHIYANR 130 ALK A + E + A+AVT+ PL+G HHIAGHIYANR Sbjct: 65 EALKEANITFEDIDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANR 124 Query: 131 LVKELQYPNMTLVVSGGHTELVSMEREGKFRIIGRTRDDAVGEAYDKVARALGFPYPGGP 190 LVKE+Q+P ++LVVSGGHTELV M+ G F +IG TRDDA GEAYDKVAR L PYPGGP Sbjct: 125 LVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGETRDDAAGEAYDKVARTLSMPYPGGP 184 Query: 191 HVDXXXXXXXXXXXXXXXWLEPDSYDFSFSGLKSAVLNVVNQSKMKGLAPDVAGIARGFQ 250 H+D WLEPDSYDFSFSGLKSAV+N V+ +K +G+ +A FQ Sbjct: 185 HIDRLAHEGKPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLAASFQ 244 Query: 251 ESVVEVLVEKAVRAVKATQAKQLLLSGGVAANKGLREALTAR-CEAEGIELIIPPPVFCT 309 ESV++VLV KA RA A KQ+LL+GGVAANKGLR L A + E IELIIPP CT Sbjct: 245 ESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLAAEFAQKENIELIIPPLSLCT 304 Query: 310 DNAAMIGAAAYVKWRHDGSTPLDMVADPGFSLE 342 DNAAMI AA + + L + A+PG +E Sbjct: 305 DNAAMIAAAGTIAYEQGKRATLALNANPGLDIE 337 >C2SEJ3.1 C2SEJ3_BACCE O-sialoglycoprotein endopeptidase Length = 338 Score = 363 bits (933), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 183/333 (54%), Positives = 226/333 (67%), Gaps = 1/333 (0%) Query: 11 VLILAIETSCDETSVAVVKDGCEVLSNMISSQIETHRAFGGVVPEVASRKHVEVITLVIE 70 ++IL IETSCDET+VAVVK+G E+++N+++SQIE+H+ FGGVVPE+ASR HVE IT+V+E Sbjct: 5 IIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLE 64 Query: 71 GALKAAGVQPEQLTAVAVTQXXXXXXXXXXXXXXXXXXXXXWGKPLIGTHHIAGHIYANR 130 ALK A + E + A+AVT+ PL+G HHIAGHIYANR Sbjct: 65 EALKEANITFEDIDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANR 124 Query: 131 LVKELQYPNMTLVVSGGHTELVSMEREGKFRIIGRTRDDAVGEAYDKVARALGFPYPGGP 190 LVKE+Q+P ++LVVSGGHTELV M+ G F +IG TRDDA GEAYDKVAR L PYPGGP Sbjct: 125 LVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGETRDDAAGEAYDKVARTLSMPYPGGP 184 Query: 191 HVDXXXXXXXXXXXXXXXWLEPDSYDFSFSGLKSAVLNVVNQSKMKGLAPDVAGIARGFQ 250 H+D WLEPDSYDFSFSGLKSAV+N V+ +K +G+ +A FQ Sbjct: 185 HIDRLAHEGKPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLAASFQ 244 Query: 251 ESVVEVLVEKAVRAVKATQAKQLLLSGGVAANKGLREALTAR-CEAEGIELIIPPPVFCT 309 ESV++VLV KA RA A KQ+LL+GGVAANKGLR L A + E IELIIPP CT Sbjct: 245 ESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLAAEFAQKENIELIIPPLSLCT 304 Query: 310 DNAAMIGAAAYVKWRHDGSTPLDMVADPGFSLE 342 DNAAMI AA + + L + A+PG +E Sbjct: 305 DNAAMIAAAGTIAYEQGKRATLALNANPGLDIE 337 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.133 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,794,596,800 Number of extensions: 63511855 Number of successful extensions: 167395 Number of sequences better than 1.0e-05: 1910 Number of HSP's gapped: 160846 Number of HSP's successfully gapped: 1930 Length of query: 349 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 213 Effective length of database: 1,779,438,163 Effective search space: 379020328719 Effective search space used: 379020328719 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 132 (55.5 bits)