BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0368.0018.p (427 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KL32.1 B3KL32_9BACI Ribonuclease, Rne/Rng family 501 e-140 B1DDQ7.1 B1DDQ7_9BACL Ribonuclease, Rne/Rng family 428 e-118 A4J7J3.1 A4J7J3_DESRM Ribonuclease G EC=3.1.4.- 346 3e-93 C0GEV2.1 C0GEV2_9FIRM Ribonuclease, Rne/Rng family 340 1e-91 B4BAQ8.1 B4BAQ8_CLOTM Ribonuclease, Rne/Rng family 328 6e-88 >B3KL32.1 B3KL32_9BACI Ribonuclease, Rne/Rng family Length = 411 Score = 501 bits (1291), Expect = e-140, Method: Compositional matrix adjust. Identities = 240/408 (58%), Positives = 304/408 (74%) Query: 15 MKQMIVHCMQHVTRMALLDNGSLVEYAAERDQQQGLVGSYYKGRVMNVLPGMQAAFVDIG 74 M+QMIVHC +MAL+++G L E+A ER ++Q +VGS+YKGRV+NVLPGMQAAFVDIG Sbjct: 1 MRQMIVHCEHETIQMALIEDGRLAEFAVERSREQSVVGSFYKGRVVNVLPGMQAAFVDIG 60 Query: 75 QKKNAFLYVDDVLHPHLERQPEVKPSIETLLQPGQEIVVQVRKEPRGGKGARVTTHYTLP 134 KKNAFLY+DDVLHPHLE+QP+ KPSI LL GQE++VQV KEPRGGKGARVTTH++LP Sbjct: 61 LKKNAFLYIDDVLHPHLEKQPKQKPSISQLLTAGQELIVQVMKEPRGGKGARVTTHFSLP 120 Query: 135 GRWMVYMPFADYVGVSKKISRESERARLKAIGERLRRQEEGIIMRTVSEDEPVEAVEGDL 194 GR MVYMP ADYV VSKKI R++ERARLK+IGE+LR EEGII+RTVSEDEP+E ++GDL Sbjct: 121 GRCMVYMPTADYVAVSKKIGRDAERARLKSIGEQLRTDEEGIIIRTVSEDEPLEFIKGDL 180 Query: 195 SFLRSQWEMITRRAQECGAPALLHSDLSIVQRFIRDAFNPQQDELMIDSAKAVREAEAFL 254 +LR +W I +A+ PALLH DL ++QRF+RDAF+P DEL+IDS + E +++L Sbjct: 181 EYLRKEWARILDKAESAPVPALLHRDLGLLQRFLRDAFDPLHDELVIDSKQKGEETKSYL 240 Query: 255 NDMAPGKYKPVRFYHGQESIFTAYGVQEQLHKSFGRKITLEGGATLIWDETEALTVIDVN 314 + PG V +Y IF AYG+ EQ+ SF RKITL G T++ D+TEA+T+IDVN Sbjct: 241 KETVPGMEPKVTYYSEGGPIFQAYGLDEQMRASFARKITLPEGVTIVVDQTEAMTIIDVN 300 Query: 315 TAQYTGGTSLEETVTRTNLLAAEEIGRLIRLRDTXXXXXXXXXXMQREEHRKMVTERLER 374 TA+Y GG + EETV +TNLLAA++I R++RL D M EEHR+ V +E Sbjct: 301 TAKYIGGDNFEETVLKTNLLAAQQIARILRLWDIGGIIIVDFIDMDHEEHRQQVVSVMEA 360 Query: 375 VISRDRTQTHILGWTHLGLLEMTRKKARHDSAGFAPAICQCCGGTGKV 422 V+ +DRT++ ++GWT LGLLEMTRKKAR S+ C CGG G V Sbjct: 361 VMRKDRTKSFVVGWTKLGLLEMTRKKARESSSLPFAKPCGTCGGRGVV 408 >B1DDQ7.1 B1DDQ7_9BACL Ribonuclease, Rne/Rng family Length = 416 Score = 428 bits (1101), Expect = e-118, Method: Compositional matrix adjust. Identities = 212/410 (51%), Positives = 281/410 (68%), Gaps = 3/410 (0%) Query: 15 MKQMIVHCMQHVTRMALLDNGSLVEYAAERDQQQGLVGSYYKGRVMNVLPGMQAAFVDIG 74 MK+M++H + + A+L +G L+++ E+ + GLVG+ YKGRV+NVLPGMQAAFVDIG Sbjct: 1 MKRMLMHGHGELLQTAVLMDGRLIDFFMEQSESSGLVGNVYKGRVVNVLPGMQAAFVDIG 60 Query: 75 QKKNAFLYVDDVLHPHLERQPEVKPSIETLLQPGQEIVVQVRKEPRGGKGARVTTHYTLP 134 KNAFLY+DD+LHPHLE+QPE KPSI L++PGQE+VVQV KEP G KGARVTTH+TLP Sbjct: 61 LGKNAFLYIDDLLHPHLEKQPEHKPSITELVKPGQELVVQVMKEPMGSKGARVTTHFTLP 120 Query: 135 GRWMVYMPFADYVGVSKKISRESERARLKAIGERLRRQEEGIIMRTVSEDEPVEAVEGDL 194 GRW+VYMP A Y+GVSKKI ESER+R++ IGERLR+ EEGIIMRT +E E E++ D+ Sbjct: 121 GRWLVYMPIAGYIGVSKKIMAESERSRIRMIGERLRQGEEGIIMRTAAEGECEESLGADV 180 Query: 195 SFLRSQWEMITRRAQECGAPALLHSDLSIVQRFIRDAFNPQQDELMIDSAKAVREAEAFL 254 LR W + +RA APA LH + +++R +RD DE+ +D EA + L Sbjct: 181 DQLRQLWTSVLQRADHAKAPAELHREAGLLRRAVRDTLTDDMDEVWLDDPSRYSEAVSLL 240 Query: 255 NDMAP---GKYKPVRFYHGQESIFTAYGVQEQLHKSFGRKITLEGGATLIWDETEALTVI 311 +M P G+ K + S+F +GV +Q+ +F +I LE G +L+WDETEALTVI Sbjct: 241 KEMTPHLAGRLKLFEARKEKVSLFDRFGVTDQIEAAFSSRIRLESGGSLVWDETEALTVI 300 Query: 312 DVNTAQYTGGTSLEETVTRTNLLAAEEIGRLIRLRDTXXXXXXXXXXMQREEHRKMVTER 371 DVNTA+Y G T LE+TV +TN+ AA+EI RL+R+RD M+ E +R+ V R Sbjct: 301 DVNTAKYIGATGLEDTVFKTNMEAADEIARLLRIRDVGGIIVIDFIDMENESNREKVMAR 360 Query: 372 LERVISRDRTQTHILGWTHLGLLEMTRKKARHDSAGFAPAICQCCGGTGK 421 L +DRT+ + GWT LGLLE+TR+KAR ++A C CGGTGK Sbjct: 361 LSDWAKKDRTKCTVFGWTRLGLLELTRRKARDNAARQLTERCPACGGTGK 410 >A4J7J3.1 A4J7J3_DESRM Ribonuclease G EC=3.1.4.- Length = 559 Score = 346 bits (887), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 185/411 (45%), Positives = 251/411 (61%), Gaps = 4/411 (0%) Query: 15 MKQMIVHCMQHVTRMALLDNGSLVEYAAERDQQQGLVGSYYKGRVMNVLPGMQAAFVDIG 74 +K+++++ + TR+A+L++ L+E ER Q LVG+ +KG+V NVLPGMQAAFVDIG Sbjct: 2 LKEIVINVQEEETRVAVLEDRVLMEVYIERSHNQRLVGNIFKGKVENVLPGMQAAFVDIG 61 Query: 75 QKKNAFLYVDDVL---HPHLERQPEVKPSIETLLQPGQEIVVQVRKEPRGGKGARVTTHY 131 +KNAFLYV+D +P Q +I +L+ GQEI+VQ+ KEP G KG RVTTH Sbjct: 62 LEKNAFLYVEDAQPSRNPEAANQSGYPVNIADILKQGQEIIVQIVKEPIGTKGPRVTTHI 121 Query: 132 TLPGRWMVYMPFADYVGVSKKISRESERARLKAIGERLRRQEEGIIMRTVSEDEPVEAVE 191 TLPGR++V MP DY+G+S++I E ER RLK + R++ + G+I+RTV+E E Sbjct: 122 TLPGRYLVLMPTVDYIGISRRIETEKERERLKELANRVKPEGMGVIVRTVAEGVDEEEFL 181 Query: 192 GDLSFLRSQWEMITRRAQECGAPALLHSDLSIVQRFIRDAFNPQQDELMIDSAKAVREAE 251 D+ L W I A C AP LLH D+ +VQR +RD F+ D L +DS + Sbjct: 182 QDIILLTKLWRRIQNCAANCSAPNLLHRDVELVQRMLRDVFSEDVDRLTVDSRSEYEKTL 241 Query: 252 AFLNDMAPGKYKPVRFYHGQESIFTAYGVQEQLHKSFGRKITLEGGATLIWDETEALTVI 311 L DM + K F +E+IF YG+ ++ K+ RK+ L+ GA L+ D+ EALT I Sbjct: 242 EIL-DMIDSRLKLKVFLDERENIFEDYGISTEMEKALKRKVWLKCGAYLVIDQAEALTAI 300 Query: 312 DVNTAQYTGGTSLEETVTRTNLLAAEEIGRLIRLRDTXXXXXXXXXXMQREEHRKMVTER 371 DVNT ++ G T+LE+TV +TNL AA EI R +RLR+ M EEHR V Sbjct: 301 DVNTGKFVGSTTLEDTVLKTNLDAAVEIARQLRLRNIGGIIIVDFIDMVEEEHRSQVLST 360 Query: 372 LERVISRDRTQTHILGWTHLGLLEMTRKKARHDSAGFAPAICQCCGGTGKV 422 LE I +D+T+T+ILG T LGL+EMTRKK R A C C G GKV Sbjct: 361 LEEEIKKDKTKTNILGITQLGLVEMTRKKVRPSLAEVVQKSCPYCEGRGKV 411 >C0GEV2.1 C0GEV2_9FIRM Ribonuclease, Rne/Rng family Length = 557 Score = 340 bits (872), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 182/407 (44%), Positives = 251/407 (61%) Query: 16 KQMIVHCMQHVTRMALLDNGSLVEYAAERDQQQGLVGSYYKGRVMNVLPGMQAAFVDIGQ 75 K+++++C TR+A+L+ VE ER Q +VG+ YKG V NVLPGMQAAFVDIG Sbjct: 3 KKIVINCDNKQTRVAVLEEDKPVEIYLERPVHQRVVGNIYKGVVANVLPGMQAAFVDIGL 62 Query: 76 KKNAFLYVDDVLHPHLERQPEVKPSIETLLQPGQEIVVQVRKEPRGGKGARVTTHYTLPG 135 ++NAFLYVDD L P K IE LL+PG+E++VQV KEP G KGAR+T T+PG Sbjct: 63 ERNAFLYVDDALLPEESNNSRGKKKIEELLRPGEEVMVQVVKEPFGSKGARLTRQITIPG 122 Query: 136 RWMVYMPFADYVGVSKKISRESERARLKAIGERLRRQEEGIIMRTVSEDEPVEAVEGDLS 195 R +V MP A+Y GVS++I ER RL+ I +R + G+I+RTV+E +A DL Sbjct: 123 RHLVLMPSAEYTGVSRRIEDPDERERLRQIIAEIRPEGHGLIVRTVAEGLDDDAFRQDLQ 182 Query: 196 FLRSQWEMITRRAQECGAPALLHSDLSIVQRFIRDAFNPQQDELMIDSAKAVREAEAFLN 255 FL W+ I R ++ AP+L++ DL ++ R IRD F Q ++L++D+ + + L+ Sbjct: 183 FLLPLWDRIQNRFRQKQAPSLIYQDLDLIYRMIRDLFTEQIEQLVVDTRYEYEKIQEALD 242 Query: 256 DMAPGKYKPVRFYHGQESIFTAYGVQEQLHKSFGRKITLEGGATLIWDETEALTVIDVNT 315 + V +Y G E +F YG++ ++ ++ R + L+ G L++D TEALTVIDVNT Sbjct: 243 VVDSSLVNRVYYYSGDEPVFDVYGIEAEIERALSRTVWLDCGGYLVFDHTEALTVIDVNT 302 Query: 316 AQYTGGTSLEETVTRTNLLAAEEIGRLIRLRDTXXXXXXXXXXMQREEHRKMVTERLERV 375 +Y G T+L +TV +TNL AA EI R +RLRD M EEHR++V E+L Sbjct: 303 GKYIGKTNLADTVFKTNLEAATEIIRQVRLRDIGGIIIIDFIDMDNEEHRRLVLEKLTEK 362 Query: 376 ISRDRTQTHILGWTHLGLLEMTRKKARHDSAGFAPAICQCCGGTGKV 422 DRT++HILG T LGL+EMTRKKAR C C G GKV Sbjct: 363 AKEDRTKSHILGLTGLGLVEMTRKKARQGLDAVLQQTCPYCHGRGKV 409 >B4BAQ8.1 B4BAQ8_CLOTM Ribonuclease, Rne/Rng family Length = 497 Score = 328 bits (841), Expect = 6e-88, Method: Compositional matrix adjust. Identities = 179/416 (43%), Positives = 254/416 (61%), Gaps = 9/416 (2%) Query: 15 MKQMIVHCMQHVTRMALLDNGSLVEYAAERDQQQGLVGSYYKGRVMNVLPGMQAAFVDIG 74 + +++V + R+ALL++ LVE ER+ + LVG+ Y+GRV +VLPGMQAAF+DIG Sbjct: 2 VSEIVVDVGINEKRVALLEDRELVELFIERNDCERLVGNIYRGRVESVLPGMQAAFIDIG 61 Query: 75 QKKNAFLYVDDVLHPHLERQ-------PEVKP-SIETLLQPGQEIVVQVRKEPRGGKGAR 126 +KNAFLYV D + P E +VK +IE +L+PGQEI VQV KEP G KG R Sbjct: 62 YEKNAFLYVGDAI-PQKEFSEDDEEIYSDVKSYNIEEILRPGQEITVQVTKEPIGTKGPR 120 Query: 127 VTTHYTLPGRWMVYMPFADYVGVSKKISRESERARLKAIGERLRRQEEGIIMRTVSEDEP 186 VTTH TLPGR MV +P ADY+G+S++I E ERA+L+ I E+++ + GII+RTVSE + Sbjct: 121 VTTHITLPGRQMVLLPNADYIGISRRIEDEEERAKLRKIAEKIKPKNMGIIVRTVSEGKR 180 Query: 187 VEAVEGDLSFLRSQWEMITRRAQECGAPALLHSDLSIVQRFIRDAFNPQQDELMIDSAKA 246 E + DL+FL W I +R Q P LH DLS++ R +RD F D +I+ + Sbjct: 181 EEDFKNDLNFLVKLWAKIKQREQSGPVPRCLHKDLSVIYRAVRDIFTWNIDRFVINDRQE 240 Query: 247 VREAEAFLNDMAPGKYKPVRFYHGQESIFTAYGVQEQLHKSFGRKITLEGGATLIWDETE 306 + + ++P V +++ +F Y + + K+ +K+ L+ G ++ + TE Sbjct: 241 YNKVLELVEMISPALKMRVEYFNKNIDLFEYYQIDSMIQKALAKKVWLKCGGYIVIERTE 300 Query: 307 ALTVIDVNTAQYTGGTSLEETVTRTNLLAAEEIGRLIRLRDTXXXXXXXXXXMQREEHRK 366 ALTVIDVNT +Y G +LE+TV RTNL A +EIG+ +RLRD M EH+K Sbjct: 301 ALTVIDVNTGKYVGVNNLEDTVLRTNLDAVKEIGKQLRLRDIGGIIIIDFIDMHDPEHQK 360 Query: 367 MVTERLERVISRDRTQTHILGWTHLGLLEMTRKKARHDSAGFAPAICQCCGGTGKV 422 V E L++V+ +DRT+T ++G T LGL+EMTRKK R C C G GK+ Sbjct: 361 QVLEALKQVLKKDRTKTTVVGMTGLGLIEMTRKKVREGLESMMLQDCPYCEGRGKI 416 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.134 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,444,638,268 Number of extensions: 97190863 Number of successful extensions: 251087 Number of sequences better than 1.0e-05: 1660 Number of HSP's gapped: 247496 Number of HSP's successfully gapped: 1695 Length of query: 427 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 288 Effective length of database: 1,751,175,118 Effective search space: 504338433984 Effective search space used: 504338433984 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)