BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0352.0015.p (393 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DCI5.1 B1DCI5_9BACL Major facilitator superfamily MFS_1 376 e-102 C2YQL2.1 C2YQL2_BACCE Multidrug resistance protein 330 2e-88 C2QNT2.1 C2QNT2_BACCE Multidrug resistance protein 327 9e-88 C2W7A2.1 C2W7A2_BACCE Multidrug resistance protein 327 2e-87 B9IY02.1 B9IY02_BACCQ Multidrug resistance protein, putative 327 2e-87 >B1DCI5.1 B1DCI5_9BACL Major facilitator superfamily MFS_1 Length = 392 Score = 376 bits (965), Expect = e-102, Method: Compositional matrix adjust. Identities = 194/370 (52%), Positives = 262/370 (70%), Gaps = 9/370 (2%) Query: 1 MIKLTALFFLIMFVIGTDTFLISPLIPTLQDLFHIPTEYSGWMVGSYALGYAIFALIAGP 60 M+K + LFFL+MF+IGTDTFLISPL+PTLQ + + T +GWM+G+Y LG A+FAL++GP Sbjct: 1 MLKYSVLFFLVMFMIGTDTFLISPLLPTLQAEYGVSTGIAGWMIGAYTLGSALFALVSGP 60 Query: 61 LSDGWDRKKVMLAGMVCFSVSTMLCGFATGFWSMFFFRFLAGVSASFTAPQVWASIPALF 120 LSDGW+R+ VM+ G+ FSVST LCGFA +W M FRFLAGVSA+FTAPQVWASIPA+ Sbjct: 61 LSDGWNRRTVMICGLAAFSVSTALCGFADNYWMMLLFRFLAGVSAAFTAPQVWASIPAVM 120 Query: 121 PTSKIAKVSGIVMAGLAASQAFGIPIGSLLASTHWYYPFFTIGACALLVAVFIFYALPEM 180 P +IAK G+ GLAA+QA G+PIGS LA+ W PF++IGA +LL+AV F LP+M Sbjct: 121 PPQRIAKTMGVAFGGLAAAQALGVPIGSWLAAADWPVPFWSIGAFSLLLAVAAFLLLPDM 180 Query: 181 KPDQGQKTKIPIFSRYIPLLNSRMARKAFLAHFLFQCGFFAAFSFIGKWVTDRFHLSVDQ 240 KP+ ++++ IFSRY+PL+ + R FLA+ L G A +FIGKW+ D F LS+ Sbjct: 181 KPN--GQSRVSIFSRYMPLITNGRTRGGFLAYLLLHLGSGTAMAFIGKWMADHFELSIGG 238 Query: 241 AGYVMFFLGLGNIVGSFGGAYVIKTLNRFNTLVVGFLVSIACFIVLPHL---PSVAAFEG 297 G VM LG G ++GS + VI+ L T+ G L+ +IV PH P+V Sbjct: 239 IGNVMMGLGCGTLLGSIISSSVIRRLGSTRTVTAGMLLLALLYIVGPHTGLSPAVM---- 294 Query: 298 VYFFIFVNMGIAFPLILGMLNSLNPTIRGTISSLANSIMYAATTLGSWIAGLIYATFNGF 357 +YF IF +G+ FPL++ +L +LN +IRGTISSLANS M A TLG+W+AGL+Y F G+ Sbjct: 295 IYFVIFTVLGVIFPLVMSLLTALNASIRGTISSLANSTMNGANTLGAWLAGLLYVHFAGY 354 Query: 358 SAVGMFAAIC 367 +++G+F+A+C Sbjct: 355 ASIGIFSAVC 364 >C2YQL2.1 C2YQL2_BACCE Multidrug resistance protein Length = 391 Score = 330 bits (845), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 172/368 (46%), Positives = 240/368 (65%) Query: 1 MIKLTALFFLIMFVIGTDTFLISPLIPTLQDLFHIPTEYSGWMVGSYALGYAIFALIAGP 60 M ++ A+FF+IMF+IGTDTFLISPL+PTLQ ++H+ TE SGWMV SYALGYA FALIAGP Sbjct: 1 MKRVLAVFFMIMFMIGTDTFLISPLLPTLQQVYHVSTELSGWMVSSYALGYAGFALIAGP 60 Query: 61 LSDGWDRKKVMLAGMVCFSVSTMLCGFATGFWSMFFFRFLAGVSASFTAPQVWASIPALF 120 +SDG +RKKVM+ GM CF++ST LCG A F M FRFLAGVSA+F +PQVWASIP L Sbjct: 61 ISDGLNRKKVMVIGMSCFALSTFLCGMAPSFLWMLAFRFLAGVSAAFVSPQVWASIPLLI 120 Query: 121 PTSKIAKVSGIVMAGLAASQAFGIPIGSLLASTHWYYPFFTIGACALLVAVFIFYALPEM 180 +I K GI AGLA SQ G+P+GS LA H+ PFF IG + L+ + I+ LPE+ Sbjct: 121 EKEQIVKAIGIATAGLAISQILGLPVGSYLAMVHYTTPFFVIGILSALLVILIYVVLPEI 180 Query: 181 KPDQGQKTKIPIFSRYIPLLNSRMARKAFLAHFLFQCGFFAAFSFIGKWVTDRFHLSVDQ 240 +P +K I RY LL ++ A+F+FQ G FAAFSF G W++ +F L V + Sbjct: 181 QPVYIGGSKTNILKRYKQLLTDSKVSLSYFAYFVFQTGNFAAFSFFGVWLSIQFGLQVHE 240 Query: 241 AGYVMFFLGLGNIVGSFGGAYVIKTLNRFNTLVVGFLVSIACFIVLPHLPSVAAFEGVYF 300 G M LGLGN+ G+ G ++ + + G + + +++LP++ ++ E ++F Sbjct: 241 IGTAMLVLGLGNLTGNILGPRIVNKIGYNLSFYGGIIFTAVLYVLLPYVKNIIFVELLFF 300 Query: 301 FIFVNMGIAFPLILGMLNSLNPTIRGTISSLANSIMYAATTLGSWIAGLIYATFNGFSAV 360 +F GI F L++ L +L+ RGT ++LAN+ MY +GS IAG+++A + F + Sbjct: 301 VLFFVTGILFVLMMRHLQNLSSAARGTGAALANASMYIGQMIGSAIAGMLFAASHNFILI 360 Query: 361 GMFAAICF 368 G F A+ + Sbjct: 361 GSFTALLY 368 >C2QNT2.1 C2QNT2_BACCE Multidrug resistance protein Length = 398 Score = 327 bits (839), Expect = 9e-88, Method: Compositional matrix adjust. Identities = 181/368 (49%), Positives = 255/368 (69%), Gaps = 1/368 (0%) Query: 1 MIKLTALFFLIMFVIGTDTFLISPLIPTLQDLFHIPTEYSGWMVGSYALGYAIFALIAGP 60 M K+ A+FFLIMFVIGTDTFLISPL+P+L++ + + E SGW+V +YALGYA+FALIAGP Sbjct: 1 MKKIMAVFFLIMFVIGTDTFLISPLLPSLREKYDVTVELSGWLVSAYALGYALFALIAGP 60 Query: 61 LSDGWDRKKVMLAGMVCFSVSTMLCGFATGFWSMFFFRFLAGVSASFTAPQVWASIPALF 120 +SDG++RKKVM+ G+ FS+ T LCG A+ F M FRFL+G+SA+F PQVWASIP L Sbjct: 61 ISDGFNRKKVMIFGLFSFSIFTFLCGLASSFELMLIFRFLSGISAAFLTPQVWASIPILL 120 Query: 121 PTSKIAKVSGIVMAGLAASQAFGIPIGSLLASTHWYYPFFTIGACALLVAVFIFYALPEM 180 P +K+ + GI AGL+ SQ GIPIGS LAS +W PFF I +LL+ + F +P + Sbjct: 121 PPNKVLRGMGIATAGLSVSQMLGIPIGSYLASINWNTPFFIISIFSLLLLIPTFLLVPSI 180 Query: 181 KPDQGQKTKIPIFSRYIPLLNSRMARKAFLAHFLFQCGFFAAFSFIGKWVTDRFHLSVDQ 240 +P + ++ K IF Y LL+S RK F A+F+FQ G F AFSF+G W++D +H SV Q Sbjct: 181 QPTE-KENKTSIFKNYQGLLSSSKVRKTFFAYFIFQLGNFCAFSFLGTWLSDDYHFSVSQ 239 Query: 241 AGYVMFFLGLGNIVGSFGGAYVIKTLNRFNTLVVGFLVSIACFIVLPHLPSVAAFEGVYF 300 G M LGLGN +GS GA VI+ + ++L+ G ++ + VL +LP++ E + Sbjct: 240 VGTAMLILGLGNTLGSLLGANVIQKIGELSSLIYGMIILSVFYSVLAYLPNILMVEVTFL 299 Query: 301 FIFVNMGIAFPLILGMLNSLNPTIRGTISSLANSIMYAATTLGSWIAGLIYATFNGFSAV 360 +F+ G+ FPL++ +L SL+ T RGTI+SL+N++MY+ TT+G +I G++Y T+ F+A+ Sbjct: 300 LMFLFTGMIFPLLMSLLQSLSSTARGTIASLSNTVMYSGTTIGGYIGGILYGTYGSFAAI 359 Query: 361 GMFAAICF 368 G F F Sbjct: 360 GFFTTAMF 367 >C2W7A2.1 C2W7A2_BACCE Multidrug resistance protein Length = 398 Score = 327 bits (837), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 168/353 (47%), Positives = 232/353 (65%) Query: 16 GTDTFLISPLIPTLQDLFHIPTEYSGWMVGSYALGYAIFALIAGPLSDGWDRKKVMLAGM 75 GTDTFLISPL+PTLQ ++ +PTE SGWMV +YALGYA+FALIAGP+SDG +RK+VML GM Sbjct: 19 GTDTFLISPLLPTLQTIYGVPTEISGWMVSTYALGYAVFALIAGPISDGLNRKRVMLGGM 78 Query: 76 VCFSVSTMLCGFATGFWSMFFFRFLAGVSASFTAPQVWASIPALFPTSKIAKVSGIVMAG 135 F++ST LCG A F M FRF AGVSA+F +PQVWASIP L ++I K GI AG Sbjct: 79 SFFAISTFLCGTAPSFGWMLTFRFCAGVSAAFVSPQVWASIPLLVSKNQIVKSIGIATAG 138 Query: 136 LAASQAFGIPIGSLLASTHWYYPFFTIGACALLVAVFIFYALPEMKPDQGQKTKIPIFSR 195 L+ +Q G+PI + LA+ H+ PFFTIG C+ ++ +FI++ PE++P +K + PI SR Sbjct: 139 LSLAQVLGLPIVAYLATIHYTTPFFTIGICSAVLVIFIYFVFPEIQPQHIEKKQQPIVSR 198 Query: 196 YIPLLNSRMARKAFLAHFLFQCGFFAAFSFIGKWVTDRFHLSVDQAGYVMFFLGLGNIVG 255 Y LL A+ A+FLFQ G FAAFSF G W+ +F L V++ G M LGLGN+ G Sbjct: 199 YKQLLGDSKTSLAYFAYFLFQTGNFAAFSFFGVWLATQFKLQVNEVGTAMLILGLGNLTG 258 Query: 256 SFGGAYVIKTLNRFNTLVVGFLVSIACFIVLPHLPSVAAFEGVYFFIFVNMGIAFPLILG 315 + G ++K L + G V +++LP+L + E +F +F GI F L++ Sbjct: 259 NIVGPRLVKKLGYMYSFYGGIFVLAGLYVILPYLKHILLVELFFFILFFITGILFVLMMS 318 Query: 316 MLNSLNPTIRGTISSLANSIMYAATTLGSWIAGLIYATFNGFSAVGMFAAICF 368 L ++ RGT ++LANS MY T+G+ +AG+++ TF+ F +G F AI + Sbjct: 319 HLQKISSVARGTGAALANSSMYIGQTIGAAVAGVLFVTFDNFIFIGSFTAILY 371 >B9IY02.1 B9IY02_BACCQ Multidrug resistance protein, putative Length = 391 Score = 327 bits (837), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 170/368 (46%), Positives = 239/368 (64%) Query: 1 MIKLTALFFLIMFVIGTDTFLISPLIPTLQDLFHIPTEYSGWMVGSYALGYAIFALIAGP 60 M ++ A+FF IMF+IGTDTFLISPL+PTLQ ++HI TE SGWMV SYALGYA FALIAGP Sbjct: 1 MKRVLAVFFTIMFMIGTDTFLISPLLPTLQQVYHISTELSGWMVSSYALGYAAFALIAGP 60 Query: 61 LSDGWDRKKVMLAGMVCFSVSTMLCGFATGFWSMFFFRFLAGVSASFTAPQVWASIPALF 120 +SD +RKKVM+ GM F++ST LCG A F M FRFLAGVSA+F +PQVWASIP L Sbjct: 61 ISDSLNRKKVMVIGMSFFALSTFLCGIAPSFLWMLTFRFLAGVSAAFVSPQVWASIPLLI 120 Query: 121 PTSKIAKVSGIVMAGLAASQAFGIPIGSLLASTHWYYPFFTIGACALLVAVFIFYALPEM 180 +I K GI AGL+ SQ G+P+GS LA H+ PFF IG + L+ + I+ LPE+ Sbjct: 121 EKEQIVKAIGIATAGLSLSQILGLPVGSYLAMIHYTTPFFVIGILSALLVILIYVVLPEI 180 Query: 181 KPDQGQKTKIPIFSRYIPLLNSRMARKAFLAHFLFQCGFFAAFSFIGKWVTDRFHLSVDQ 240 +P ++ KI I Y LL+ ++ A+F+FQ G FAAFSF G W++ +F L + + Sbjct: 181 QPVHIRENKINILKHYKQLLSDSKVSLSYFAYFVFQTGNFAAFSFFGVWLSIQFGLQIHE 240 Query: 241 AGYVMFFLGLGNIVGSFGGAYVIKTLNRFNTLVVGFLVSIACFIVLPHLPSVAAFEGVYF 300 G M LGLGN+ G+ G ++ + + G + + +++LPH+ ++ E ++F Sbjct: 241 IGTAMLVLGLGNLTGNIFGPRIVNKIGYNLSFYGGIIFTAVLYVLLPHVNNIILVELLFF 300 Query: 301 FIFVNMGIAFPLILGMLNSLNPTIRGTISSLANSIMYAATTLGSWIAGLIYATFNGFSAV 360 +F GI F L++ L +++ RGT ++LAN+ MY +G+ IAG+++A + F V Sbjct: 301 VLFFVTGILFVLMMRHLQNMSSVARGTGAALANASMYIGQMIGAAIAGMLFAASHNFIFV 360 Query: 361 GMFAAICF 368 G F AI + Sbjct: 361 GSFTAILY 368 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.332 0.143 0.453 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,198,201,806 Number of extensions: 92269319 Number of successful extensions: 483433 Number of sequences better than 1.0e-05: 10582 Number of HSP's gapped: 482279 Number of HSP's successfully gapped: 10586 Length of query: 393 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 255 Effective length of database: 1,760,596,133 Effective search space: 448952013915 Effective search space used: 448952013915 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (22.0 bits) S2: 132 (55.5 bits)