BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0350.0046.p (444 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DIN9.1 B1DIN9_9BACL Two component transcriptional regulator, A... 465 e-129 B7GJK9.1 B7GJK9_ANOFW DNA-binding response regulator (Contains R... 280 2e-73 C5D8H7.1 C5D8H7_9BACI Two component transcriptional regulator, A... 198 9e-49 Q9K690.1 Q9K690_BACHD Two-component response regulator 197 2e-48 A9AWB3.1 A9AWB3_HERA2 Two component transcriptional regulator, A... 155 7e-36 >B1DIN9.1 B1DIN9_9BACL Two component transcriptional regulator, AraC family Length = 451 Score = 465 bits (1196), Expect = e-129, Method: Compositional matrix adjust. Identities = 244/454 (53%), Positives = 312/454 (68%), Gaps = 17/454 (3%) Query: 1 MYRLLIADDEPLEREGLELTVERSMPGIFRFIHAGNGRKAIECAEEHRPHIVILDINMPG 60 MYRLLIADDE LEREGLE + R +P F+ A NGR+AIE AEE RPHI+++DINMPG Sbjct: 1 MYRLLIADDEALEREGLEHLIHRMLPDRFQIAFADNGRRAIEQAEEFRPHIIMMDINMPG 60 Query: 61 IXXXXXXXXXXXXXXXTXXXXVLVTAYDYFAYAQEALSLGAKEYILKPAKREQIIGTLKR 120 I T +LVTAYD+FAYA+EA+SLG KEYI+KPA REQI TL + Sbjct: 61 IQGLQAIREIKTRLPDTKF--ILVTAYDFFAYAKEAVSLGVKEYIVKPAGREQISSTLNQ 118 Query: 121 LISEIEREKQLRAEELELRHKMSQLLPLVENELALILMVDQTADSTASQLSEWLDFPLDQ 180 LI E+EREK R EEL LR K+SQL PLVENEL+L+LMVDQ D+ +LS+WL FPLD+ Sbjct: 119 LIEELEREKSKRTEELHLRDKVSQLQPLVENELSLLLMVDQVLDANEEKLSDWLSFPLDE 178 Query: 181 GSAIVVAFEGHPSLQEKKKIYDHFRSFVKIHSSASIVSSLIDHHLVIFVRKPLSMGENDW 240 G A+VVA +KKK+Y+ FR F+K + + IVSSLID H+ IF+R S + W Sbjct: 179 GCAVVVALPKQIYTLDKKKLYETFRGFIKTYGISCIVSSLIDLHMAIFIRNDTS--DALW 236 Query: 241 RERNKEIARQLFELASQQTGIQAAVGIGSLRRGEEGFRESYFEAVFASTLQEHGEAYSHF 300 + K +L LA +Q + VGIGS++ G G+R+SYFEAVFAS + H F Sbjct: 237 KRSIKPFGEKLCSLAERQFQLPITVGIGSVQSGAGGWRKSYFEAVFASDVDRHVGEVRDF 296 Query: 301 EELKRIGSPHDPGPISTAP-----------QQSYVISALHRIREQREEQTLTVLGRAKKY 349 E + + G+ + + P Q+SYVISAL RIREQRE+QT+ V+ +AK+Y Sbjct: 297 EGVVQ-GTGSNVAAATANPASSDEHSDSEDQRSYVISALQRIREQREQQTINVMDKAKQY 355 Query: 350 IGERYTDDLSLEEVADYVHLNPHYFSKIFKQEYGETFIDFVTRLRIDKAISLIGEG-RLS 408 IG +T++LSLEE A++VHLNPHYFSK+FKQ+ G TFID++T LRI+KA LI L+ Sbjct: 356 IGLHFTEELSLEETAEHVHLNPHYFSKVFKQQVGATFIDYLTGLRIEKAKQLISSADELA 415 Query: 409 LKEVSFEAGYKDPNYFSRVFKKITGVSPTEFRGK 442 LKEV FE GYKDPNYFSRVFK++TG++PTE+R + Sbjct: 416 LKEVCFEVGYKDPNYFSRVFKRVTGLTPTEYRSQ 449 >B7GJK9.1 B7GJK9_ANOFW DNA-binding response regulator (Contains REC and AraC-type DNA-binding domain) Length = 428 Score = 280 bits (716), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 165/450 (36%), Positives = 247/450 (54%), Gaps = 57/450 (12%) Query: 1 MYRLLIADDEPLEREGLELTVERSMPGIFRFIHAGNGRKAIECAEEHRPHIVILDINMPG 60 MY+LLIADDEPLEREGL+L +ER+ P F HA +GR AI+ E+HRPHI+ +D+ MPG Sbjct: 19 MYKLLIADDEPLEREGLQLMIERAFPHTFTIFHAEHGRSAIQQVEQHRPHIIFMDMKMPG 78 Query: 61 IXXXXXXXXXXXXXXXTXXXXVLVTAYDYFAYAQEALSLGAKEYILKPAKREQIIGTLKR 120 I V++TAYDYF YA+EA+S G EY+LKPAK++Q+I L++ Sbjct: 79 IQGLEAIAEIRKMDAQAKI--VILTAYDYFTYAKEAISFGVSEYVLKPAKKQQMIDLLQK 136 Query: 121 LISEIEREKQLRAEELELRHKMSQLLPLVENELALILMVDQTADSTASQLSEWLDFPLDQ 180 L+ +I E+ +R ++L R K+ QL L E+A + D A+ ++F + Sbjct: 137 LLQQIAEEQAMREQQLATREKLVQLQAL--GEMAWTWLFMGKMDECAAHTFTGMEF--ES 192 Query: 181 GSAIVVAFEGHPSLQE-------KKKIYDHFRSFVKIHSS---ASIVSSLIDHHLVIFVR 230 G AIVV E + + K+ I R + + A + + D H++ FV+ Sbjct: 193 GYAIVVELEKADACEREKWEEKMKQCIKQQRRCLCSLLNQRQMAIFIEAKQDEHVISFVQ 252 Query: 231 KPLSMGENDWRERNKEIARQLFELASQQTGIQAAVGIGSLRRGEEGFRESYFEAVFASTL 290 L E ++R K +GIG+++ G +G + SY EA A Sbjct: 253 SLLKQLEKVLQQRVK-------------------IGIGTIQSGVDGMKRSYKEASIAVRY 293 Query: 291 QEHGEAYSHFEELKRIGSPHDPGPISTAPQQSYVISALHRIREQREEQTLTVLGRAKKYI 350 S F + + D P++ +Q+ + + +V+ + + ++ Sbjct: 294 ------VSSFSRVMHV----DDVPLTDEVEQTTIKTGG------------SVIEQVEMFL 331 Query: 351 GERYTDDLSLEEVADYVHLNPHYFSKIFKQEYGETFIDFVTRLRIDKAISLIGEGRLSLK 410 E Y D++LEEVA YVHL P+YFSK+FK+E G+TFID+VT LRI+KA L+ + L++K Sbjct: 332 QENYCYDVTLEEVAKYVHLTPYYFSKLFKKETGQTFIDYVTHLRIEKAKQLMRDEGLTVK 391 Query: 411 EVSFEAGYKDPNYFSRVFKKITGVSPTEFR 440 E + GYKDPNYFSRVFKK+T ++PTE+R Sbjct: 392 EACYRVGYKDPNYFSRVFKKVTNMTPTEYR 421 >C5D8H7.1 C5D8H7_9BACI Two component transcriptional regulator, AraC family Length = 515 Score = 198 bits (503), Expect = 9e-49, Method: Compositional matrix adjust. Identities = 159/517 (30%), Positives = 243/517 (47%), Gaps = 85/517 (16%) Query: 3 RLLIADDEPLEREGLELTVERSMPGIFRFIHAGNGRKAIECAEEHRPHIVILDINMPGIX 62 ++ I DDE LER+ L+ + +P + A NGR+A+E A E++P +++DI MPGI Sbjct: 2 KIAIVDDEVLERKALQKMIRDHLPNMEVVAEAANGREAVEIANEYKPDAMLIDIKMPGID 61 Query: 63 XXXXXXXXXXXXXXTXXXXVLVTAYDYFAYAQEALSLGAKEYILKPAKREQIIGTLKRLI 122 ++V+A+D F YA++A+ G KEY+LKP+++E++IG L+R+ Sbjct: 62 GLEAIELIRRHH--PDMKFIIVSAFDTFEYAKQAMRHGVKEYLLKPSRKEEVIGALRRVY 119 Query: 123 SEIEREKQLRAEELELRHKMSQLLPLVENELALILMVDQTADSTASQLSEWLDFPLDQGS 182 E+ E++ E EL+ ++ QL LVE E +LM+++ + Q F +D G Sbjct: 120 DELMEERKKEEENRELQQRVHQLQKLVEKEWLSVLMLEEVSSEEWKQWETLFPFSIDSGM 179 Query: 183 AIVVAFEGHPSLQEKKKIYDHFRSFVKIHSSAS--IVSSLIDHHLVIFVRKPLSMGENDW 240 +V+ F PS KK+++ H+ V + +A+ ++ +ID + I + E W Sbjct: 180 FMVIQF---PS-GGKKEVWKHWVEQVLLEKAATYYVIGRIIDGQMPILFFTDIP--EKTW 233 Query: 241 RERNKEIARQLFELASQQTGIQAAVGIGSLRRGEEGFRESYFEAVFA-STLQEHGEAYSH 299 + + +A L + +Q +G+GS EG R SY+EA+ A +A S Sbjct: 234 KPMIQSLAHDLVQQFEKQYEETLYIGLGSPASQLEGLRYSYYEALAAVQYYASQKKAKSG 293 Query: 300 F---------------EELKRIGSPHDPGPISTAPQQ--SYVIS-ALHR---IREQREEQ 338 F E KR+ G A Q SY+ A H I +Q+ E+ Sbjct: 294 FLPKKAVLASAAIDQTEREKRLFDVVREGDFKQALTQCLSYIEEIAFHHPFPIVKQKMEE 353 Query: 339 TLTVLGRAKKYIGERYTDDL------SLEEV----------------------------- 363 T +LGR G Y SLEE+ Sbjct: 354 TFILLGRMLTDFGISYERTTTFHSCGSLEELKRTATEQLQHMVHYIQAWRHQQANGKIGK 413 Query: 364 -ADYVHLNPH-----------------YFSKIFKQEYGETFIDFVTRLRIDKAISLIGEG 405 DY+ + H YFSK+FK +G TFID+VT +RI +A + + Sbjct: 414 AKDYIDEHYHHPLTLEEVAEYVGISPYYFSKLFKDRFGMTFIDYVTEVRIARAKKEMADP 473 Query: 406 RLSLKEVSFEAGYKDPNYFSRVFKKITGVSPTEFRGK 442 SLKE+ F GY DPNYFSRVFKK TG+SPTE+R K Sbjct: 474 NKSLKEICFLVGYNDPNYFSRVFKKHTGMSPTEYRKK 510 >Q9K690.1 Q9K690_BACHD Two-component response regulator Length = 530 Score = 197 bits (501), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 153/522 (29%), Positives = 250/522 (47%), Gaps = 90/522 (17%) Query: 1 MYRLLIADDEPLEREGLELTVERSMPGIFRFIHAGNGRKAIECAEEHRPHIVILDINMPG 60 M +LI DDE +EREGL+L + + P I A NGR+AIE A E +P ++++DI MPG Sbjct: 1 MINVLIVDDEQIEREGLKLFL-KDRPNIHIVGEASNGRQAIEKALETQPDLMMMDIKMPG 59 Query: 61 IXXXXXXXXXXXXXXXTXXXXVLVTAYDYFAYAQEALSLGAKEYILKPAKREQIIGTLKR 120 + T ++V+A+D F YA+E + G KEY+LKP +E ++ L R Sbjct: 60 VDGVQAVKEIKQQLPETEF--IMVSAFDTFEYAREVMRYGVKEYLLKPTTKEDVLTALDR 117 Query: 121 LISEIEREKQLRAEELELRHKMSQLLPLVENELALILMVDQTADSTASQLSEWLDFPLDQ 180 ++ EIE+ ++ + ++ +L+ ++ Q+ V+ E L L++D D + +EWL + Sbjct: 118 IVGEIEQAREEKNDQYKLQQRLEQISSFVQTESILYLLMDHIQDYEWMEWNEWLRTE-QE 176 Query: 181 GSAIVVAFEGHPS---LQEKKKIYDHFRSFVKIHSSASIVSSLIDHHLVIFVRKPLSMGE 237 G A+V +F EK++ + + + + S V I HHL I + L+ E Sbjct: 177 GYAVVFSFHQQGKEIRKTEKQQWHARIKKEIGLQLPKSTVGPFIGHHLPILM---LTENE 233 Query: 238 NDW--RERNKEIARQLFELASQQTGIQAAVGIGSLRRGEEGFRESYFEAVFA-STLQEHG 294 N +ER + + + L ++ + G+G + R F SY EA+ A + +H Sbjct: 234 NGMTKQEREQVVIQLLHKVKQAVQPAKVKTGVGGIYRL-HFFSTSYREALLALDIIYDHK 292 Query: 295 EAYSHF---------------EELKRIGSPHDPGPISTAPQ------QSYVISALHRIRE 333 +A +F E ++ G A Q Q+ + + H + + Sbjct: 293 QASYYFYDKNVKIRADEQLPIERENKLIEAIKSGDGEKALQAFDHYVQAILRCSKHPLHD 352 Query: 334 QRE--EQTLTVLGRAKKYIG-----------------------------------ERYTD 356 R+ +Q +LGR +G R TD Sbjct: 353 MRKYLQQLFIILGRLLNEMGLHWETAQDFARFSTVHQVTEHGKSEILHIVRTLQEWRTTD 412 Query: 357 DLSLEEVA-DYVH-----------------LNPHYFSKIFKQEYGETFIDFVTRLRIDKA 398 + SL +A DYVH L+P+Y SK+FK+ + TF ++VT+LR++ A Sbjct: 413 EQSLMLLARDYVHDHFREPLTLDDLAKHIGLSPYYVSKLFKERFDLTFSEYVTQLRVEHA 472 Query: 399 ISLIGEGRLSLKEVSFEAGYKDPNYFSRVFKKITGVSPTEFR 440 L+ + SLKE+++E GYKDPNYFSRVFKK+TG SP+++R Sbjct: 473 KQLLSLTQKSLKEITYEIGYKDPNYFSRVFKKLTGKSPSDYR 514 >A9AWB3.1 A9AWB3_HERA2 Two component transcriptional regulator, AraC family Length = 414 Score = 155 bits (393), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 122/452 (26%), Positives = 217/452 (48%), Gaps = 52/452 (11%) Query: 2 YRLLIADDEPLEREGLELTVERSMPGIFRFI-HAGNGRKAIECAEEHRPHIVILDINMPG 60 Y++ + +DE + REG+ ++ + G ++F A +G A+ E RP I+I DI MP Sbjct: 3 YKVFLVEDEIIAREGIRDAIDWAAAG-YQFCGEASDGEIALPLIRERRPDILITDIKMPF 61 Query: 61 IXXXXXXXXXXXXXXXTXXXXVLVTAYDYFAYAQEALSLGAKEYILKPAKREQIIGTLKR 120 + T ++++ +D F YAQEA+ +G +Y+LKP + ++ L++ Sbjct: 62 MDGLQLCRIVKETLPTTKI--IILSGHDEFRYAQEAMQIGVTQYLLKPIVAQDLLAALRK 119 Query: 121 LISEIEREKQLRAEELELRHKMSQLLPLVENELALILMVDQTADSTASQLSEWLDFPLDQ 180 + S+I+ E+Q +A+ L+ +M P++ L L+ ++ + + + L+ L Sbjct: 120 IASQIDGERQAKAQLETLQAQMFDHQPMLRERCLLDLVSGSSSAADFMEQARNLEIDLLA 179 Query: 181 GSAIVVAFEGHPSLQEKKKIYDHFRSFVKIHSSASIVSSLI----DHHL---VIFVRKPL 233 V+ P +Y ++ V + +AS+ S + H L ++ VR Sbjct: 180 PWYQVLVMHAMPPSAATAPLYTLYQQ-VDVTVAASLNQSPLVVAFKHGLEDTILIVR--- 235 Query: 234 SMGEN--DWRERNKEIARQLFELASQQTGIQAAVGIGSLRRGEEGFRESYFEAVFASTLQ 291 GE D ++ + +A + + ++Q G +A +GIG + R S FA L Sbjct: 236 --GETRADMTQQAERLATAMRQRVAEQLGCRAIIGIG-----DPTERLSLIPQSFAEALA 288 Query: 292 EHGEAYSHFEELKRIGSPHDPGPISTAPQQSYVISALHRIREQREEQTLTVLGRAKKYIG 351 + S FE P + P +Q + ++ +A YI Sbjct: 289 Q----ISSFER------PAESDP-----------------SDQGQFHGGAIMLKALAYID 321 Query: 352 ERYTDD-LSLEEVADYVHLNPHYFSKIFKQEYGETFIDFVTRLRIDKAISLIGEGRLSLK 410 Y D +SL + A +V L+P YFS +F++E GETFID++T++RI KAI L+ L+ Sbjct: 322 TNYADPAMSLGQAAAHVLLSPTYFSALFRREVGETFIDYLTQVRIRKAIELLRSTSLTAS 381 Query: 411 EVSFEAGYKDPNYFSRVFKKITGVSPTEFRGK 442 E+++ GY++P YF VF+K+ G P EFR + Sbjct: 382 EIAYRIGYQNPRYFYSVFRKVVGQPPNEFRQR 413 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,422,861,656 Number of extensions: 94327754 Number of successful extensions: 366591 Number of sequences better than 1.0e-05: 5111 Number of HSP's gapped: 372781 Number of HSP's successfully gapped: 5598 Length of query: 444 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 305 Effective length of database: 1,751,175,118 Effective search space: 534108410990 Effective search space used: 534108410990 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)