BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0350.0029.p (442 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DIP6.1 B1DIP6_9BACL Two component transcriptional regulator, A... 553 e-155 B3K590.1 B3K590_9BACI Response regulator receiver 543 e-153 A9AWB3.1 A9AWB3_HERA2 Two component transcriptional regulator, A... 147 3e-33 B1D595.1 B1D595_9BACL Two component transcriptional regulator, A... 132 8e-29 A6LW09.1 A6LW09_CLOB8 Response regulator receiver protein 129 4e-28 >B1DIP6.1 B1DIP6_9BACL Two component transcriptional regulator, AraC family Length = 444 Score = 553 bits (1424), Expect = e-155, Method: Compositional matrix adjust. Identities = 272/447 (60%), Positives = 342/447 (76%), Gaps = 8/447 (1%) Query: 1 MFNVLVVDDEPLICKXXXXXXXXXXXEIGHIYTANSGFEALDVIRMEEVDLLVTDIQMGA 60 M+N+LVVDDEPLICK +I I+ A++G+EALDV+R +++DLL+TDIQMG Sbjct: 1 MYNILVVDDEPLICKGLSSVLASSGIDISAIHMAHNGYEALDVLRTDDIDLLITDIQMGT 60 Query: 61 MSGIELMQHAKLAKPWVQTIIISAHETFQYAQMAVRLGAKDYLIKPLNSEHFLDSVRNVL 120 M+GIELMQ AKL KPWVQTIIISAHETF YAQMA+RLGAKDYLIKPLN+E FLDSVRNVL Sbjct: 61 MNGIELMQQAKLIKPWVQTIIISAHETFHYAQMAIRLGAKDYLIKPLNNEQFLDSVRNVL 120 Query: 121 LKMDKPSP-ELATFMAGIGESFRLEEPLPEYSRLLNALIEEPASVLGDEQKLRKLDE--- 176 LK+ KP P E +AG+ E F ++E P+ LN L S L + +R L E Sbjct: 121 LKLHKPEPAEQEKLIAGMQEHFHMDELNPQSVDWLNQLASGQPS-LKVQDIIRILKEKHG 179 Query: 177 LKLQGPFFSVIKIKLPLPEEDGEKKYTFRDRELLRYAALNIAKELLDQEWSTVAFYSPEE 236 ++L+GP+FS+I+I+L L D ++ T D LLRYAALNI EL D+ W+ AFY+ E Sbjct: 180 IRLEGPYFSMIRIRLNLT--DRNRELTKADEGLLRYAALNIVNELFDEHWNNTAFYASER 237 Query: 237 EITVVIQWDEKTYEESAA-GQINRLDVLGRTLHLNIHKYLHLNAVIGISQILKGLSFMDV 295 EIT+++QW+E Y E+A+ G +N LD++GR+L NI KYL + +VIGISQILKG+ F+DV Sbjct: 238 EITIILQWNETQYGETASSGIMNELDMIGRSLQFNIQKYLGIASVIGISQILKGIEFIDV 297 Query: 296 LNRQASKAIQWNKEHSDYYVFYYGDFNWSSYAADPSAEELHTHSNLIVQKAKEYIDENYA 355 L Q KA+ N H D+YVFYYGDFNW+ Y+ P+ EE ++LIV+KA EYI++NYA Sbjct: 298 LQDQVIKALSCNDRHKDHYVFYYGDFNWNQYSQRPTEEEFTAQTSLIVEKAMEYINQNYA 357 Query: 356 QKGLTIHEVAKKNHVSPNYLSYLFKKNTGHNLWEYVIKLRMEDSREMLLHTDLRRYEIAE 415 QKGLT+HEVA+ NHVSPNYLSYLFKK TG+NLWEYV+KLRME+S+ +LL TD+RRYEI+E Sbjct: 358 QKGLTLHEVAQNNHVSPNYLSYLFKKETGYNLWEYVVKLRMEESKRLLLQTDMRRYEISE 417 Query: 416 RVGYESPEHFSKIFKKYYGISPSELKK 442 +VGYESPEHFSKIFKKYYG+SPSELKK Sbjct: 418 KVGYESPEHFSKIFKKYYGMSPSELKK 444 >B3K590.1 B3K590_9BACI Response regulator receiver Length = 439 Score = 543 bits (1400), Expect = e-153, Method: Compositional matrix adjust. Identities = 268/445 (60%), Positives = 342/445 (76%), Gaps = 9/445 (2%) Query: 1 MFNVLVVDDEPLICKXXXXXXXXXXXEIGHIYTANSGFEALDVIRMEEVDLLVTDIQMGA 60 M+N+LVVDDEPLICK I I TA SG EALD IRM ++DLLVTDIQMG Sbjct: 1 MYNILVVDDEPLICKGLAGLLTSSGLAIDGITTAYSGQEALDYIRMGDIDLLVTDIQMGE 60 Query: 61 MSGIELMQHAKLAKPWVQTIIISAHETFQYAQMAVRLGAKDYLIKPLNSEHFLDSVRNVL 120 M+GIELMQ AK+ KPWVQTIIISAHETFQYAQ A++LGAKDYLIKPLNSE FLDSVR+VL Sbjct: 61 MNGIELMQQAKIVKPWVQTIIISAHETFQYAQRALQLGAKDYLIKPLNSEQFLDSVRSVL 120 Query: 121 LKMDKPSPELATFMAGIGESFRLEEPLPEYSRLLN---ALIEEPASVLGDEQKLRKLDEL 177 LKMD+P+P++ + E FR+EEP E LN ++ +P++ G ++ EL Sbjct: 121 LKMDRPAPQVEPLLMADNEHFRMEEPPSERIERLNERLSMEPDPSATAGPDES-----EL 175 Query: 178 KLQGPFFSVIKIKLPLPEEDGEKKYTFRDRELLRYAALNIAKELLDQEWSTVAFYSPEEE 237 L GP+F+VIK+KL L E D ++ D L++YAALNIAKELL+QE T+ FYSPE + Sbjct: 176 GLVGPYFAVIKMKLGLAE-DRSASFSSHDINLIQYAALNIAKELLEQEPHTLVFYSPERD 234 Query: 238 ITVVIQWDEKTYEESAAGQINRLDVLGRTLHLNIHKYLHLNAVIGISQILKGLSFMDVLN 297 + +++QW E+ EE+A+G+I+ L+++GR+LH ++ +L + +GISQIL+G F+ VL+ Sbjct: 235 VNIILQWSEQEMEENASGKIHHLEMIGRSLHHHVELHLKRSCTVGISQILRGREFLSVLS 294 Query: 298 RQASKAIQWNKEHSDYYVFYYGDFNWSSYAADPSAEELHTHSNLIVQKAKEYIDENYAQK 357 RQA KA+ W+++ D++VFYYGDFNW +YA + S E L + SN IV+ ++YIDE+Y QK Sbjct: 295 RQADKAMLWSEQLHDFHVFYYGDFNWHNYAQETSQEVLSSQSNRIVENTRQYIDEHYRQK 354 Query: 358 GLTIHEVAKKNHVSPNYLSYLFKKNTGHNLWEYVIKLRMEDSREMLLHTDLRRYEIAERV 417 GLTIH+VAK NHVSPNYLSYLFKK TG +LWEYV+KLRME+SR ++L+TDLRRYEIAERV Sbjct: 355 GLTIHDVAKNNHVSPNYLSYLFKKYTGSSLWEYVVKLRMEESRALILNTDLRRYEIAERV 414 Query: 418 GYESPEHFSKIFKKYYGISPSELKK 442 GYESPEHFSKIFKKYYG+SPSELKK Sbjct: 415 GYESPEHFSKIFKKYYGVSPSELKK 439 >A9AWB3.1 A9AWB3_HERA2 Two component transcriptional regulator, AraC family Length = 414 Score = 147 bits (370), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 111/409 (27%), Positives = 195/409 (47%), Gaps = 31/409 (7%) Query: 34 ANSGFEALDVIRMEEVDLLVTDIQMGAMSGIELMQHAKLAKPWVQTIIISAHETFQYAQM 93 A+ G AL +IR D+L+TDI+M M G++L + K P + II+S H+ F+YAQ Sbjct: 35 ASDGEIALPLIRERRPDILITDIKMPFMDGLQLCRIVKETLPTTKIIILSGHDEFRYAQE 94 Query: 94 AVRLGAKDYLIKPLNSEHFLDSVRNVLLKMDKPSPELATFMAGIGESFRLEEPLPEYSRL 153 A+++G YL+KP+ ++ L ++R + ++D A + F + L E R Sbjct: 95 AMQIGVTQYLLKPIVAQDLLAALRKIASQIDGERQAKAQLETLQAQMFDHQPMLRE--RC 152 Query: 154 LNALIEEPASVLGDEQKLRKLDELKLQGPFFSVIKIKLPLPEEDGEKKYTFRDRELLRYA 213 L L+ +S ++ R L E+ L P++ V+ + P YT L + Sbjct: 153 LLDLVSGSSSAADFMEQARNL-EIDLLAPWYQVLVMHAMPPSAATAPLYT-----LYQQV 206 Query: 214 ALNIAKELLDQEWSTVAFYSPEEEITVVIQWDEKTYEESAAGQINRLDVLGRTLHLNIHK 273 + +A L +Q VAF E+ ++++ E+ A + + L + + + Sbjct: 207 DVTVAASL-NQSPLVVAFKHGLEDTILIVRG------ETRADMTQQAERLATAMRQRVAE 259 Query: 274 YLHLNAVIGISQILKGLSFMDVLNRQASKAIQWNKEHSDYYVFYYGDFNWSSYAADPSAE 333 L A+IGI + LS + +A I + ++ +DPS + Sbjct: 260 QLGCRAIIGIGDPTERLSLIPQSFAEALAQISSFERPAE---------------SDPS-D 303 Query: 334 ELHTHSNLIVQKAKEYIDENYAQKGLTIHEVAKKNHVSPNYLSYLFKKNTGHNLWEYVIK 393 + H I+ KA YID NYA +++ + A +SP Y S LF++ G +Y+ + Sbjct: 304 QGQFHGGAIMLKALAYIDTNYADPAMSLGQAAAHVLLSPTYFSALFRREVGETFIDYLTQ 363 Query: 394 LRMEDSREMLLHTDLRRYEIAERVGYESPEHFSKIFKKYYGISPSELKK 442 +R+ + E+L T L EIA R+GY++P +F +F+K G P+E ++ Sbjct: 364 VRIRKAIELLRSTSLTASEIAYRIGYQNPRYFYSVFRKVVGQPPNEFRQ 412 >B1D595.1 B1D595_9BACL Two component transcriptional regulator, AraC family Length = 421 Score = 132 bits (332), Expect = 8e-29, Method: Compositional matrix adjust. Identities = 123/459 (26%), Positives = 218/459 (47%), Gaps = 56/459 (12%) Query: 1 MFNVLVVDDEPLICKXXXXXXXXXXXEIGHIYTANSGFEALDVIRMEEVDLLVTDIQMGA 60 M+ ++++DD+ + + + A G L +I D+++TDI M Sbjct: 1 MWKIVIIDDDFQVVRGLRKAIPWEELDAEFAGDAIDGEAGLKLIEEVNPDIVLTDIYMPE 60 Query: 61 MSGIELMQHAKLAKPWVQTIIISAHETFQYAQMAVRLGAKDYLIKPLNSEHFLDSVRNVL 120 M+GI++++ K + +I+S + F+YA+ A+RLG DYL KP+ +D +R VL Sbjct: 61 MNGIQMIEALKHQSFTGRFVILSGYNDFEYARTALRLGVDDYLTKPVT----VDQIRQVL 116 Query: 121 LKMDKPSPELATFMAGIGESFRLEEPLPEY------SRLLNALI---EEPASV--LGDEQ 169 + E T++ + ++ P + + +LN L E PA++ D+Q Sbjct: 117 AETIHKLEE--TYLQRLEQTEEPSYPAKNWRQEEWTASILNGLTQPEELPAALSEWRDKQ 174 Query: 170 KLRKLDELKLQGPFFSVIKIKLPLPEEDGEKKYTFRDRELLRYAALNIAKELLDQEWSTV 229 F+V+ +++ E + + D L R+A NI++E+L EW T Sbjct: 175 --------------FTVMVLEVAWTERT--RNISIADWNLFRFAVANISEEVLLGEWRTA 218 Query: 230 AF-YSPEEEITVVIQWDEKTYEESAAGQINRLDVLGRTLHLNIHKYLHLNAVIGISQILK 288 +F + V+++ + T A RL G + + Y+ L+A G+ + Sbjct: 219 SFVWLFGNYAAVLLRSEPGTDALHTASAAERL---GGLIINYLKSYIGLDARFGLGRTKD 275 Query: 289 GLSFMDVLNRQASKAIQWNKEHSDYYVFYYGDFNWSSYAADPSAEEL-----HTHSNLIV 343 S+ ++ +A+Q E D A +P A EL H V Sbjct: 276 --SWQEI-KASCDEALQGLLEDPDR----------EQQAEEPQATELSFNTIHEKHRKAV 322 Query: 344 QKAKEYIDENYAQKGLTIHEVAKKNHVSPNYLSYLFKKNTGHNLWEYVIKLRMEDSREML 403 Q EY+ +YA+ +T+ ++A + ++S NYL+ LFKK TG YVI++R+E ++ +L Sbjct: 323 QYMIEYVHTHYAED-ITLEQLASQLYISKNYLNQLFKKVTGETFTNYVIRVRIEKAKVLL 381 Query: 404 LHTDLRRYEIAERVGYESPEHFSKIFKKYYGISPSELKK 442 L YE++E VGY++ +F+ +FKKY G++PSEL K Sbjct: 382 LEGKHLIYEVSEMVGYQNVPYFTTLFKKYCGVTPSELMK 420 >A6LW09.1 A6LW09_CLOB8 Response regulator receiver protein Length = 446 Score = 129 bits (325), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 115/436 (26%), Positives = 207/436 (47%), Gaps = 51/436 (11%) Query: 30 HIYTANSGFEALDVIRMEEVDLLVTDIQMGAMSGIELMQHAKLAKPWVQTIIISAHETFQ 89 IY A +G EA+++ D+++ DI+M + GI+ ++ P + +II++A++ F Sbjct: 30 EIYEAKNGREAIELSESIRPDIVIIDIKMPGIDGIQALKEMTATLPNLYSIILTAYDYFD 89 Query: 90 YAQMAVRLGAKDYLIKPLNSEHFLDSVRNVLLKMDKPSPELATFMAGIGESFRLEEPLPE 149 +A AV++ K+YL+KP E ++ + V +K K E + I + ++ LP Sbjct: 90 FALEAVKINVKEYLLKPFTKEEIIEKIA-VGIKWVKKEQEKRK--SEIKDKEKIYTLLP- 145 Query: 150 YSRLLNALIEEPASVLGDEQKLRKLD--------ELKLQGPFFSVIKIKLPLPEEDGEKK 201 ++E S L KL+ +D ++ + VI IK K Sbjct: 146 -------VLENQLSDLIINDKLKGVDYGMYLQCLDMSFMNSYAMVISIK---------DK 189 Query: 202 YTFRD-----RELLRYAALNIAKELLDQEWSTVAFYSPEEEITVVIQWDEKTYEESAAGQ 256 Y +++ R+ +R KE +++ + + Y EE+T IQ D + E+ + + Sbjct: 190 YAYKNISRVERDQIRIKIGEYVKEYINRRYKCIGNYVFYEELTYFIQIDNEETEDFKSLE 249 Query: 257 INRLDVLGRTLHLNIHKYLHLNAVIGISQILKGLSFMDVLNRQASKAIQWNKEHSDYYVF 316 I+ L L I K +++ G+ +I + + RQA K + +N ++ + + Sbjct: 250 ID----LAFNLRREIKKRFNISIRAGLGEIFDSVEQIVESYRQAMKCLVYNSDNVN--II 303 Query: 317 YYGDFNW----SSYAADPSAEEL---HTHSNLIVQK----AKEYIDENYAQKGLTIHEVA 365 Y D S++ S + + +SN I K K++I EN + L + +VA Sbjct: 304 YIDDIEGKLMNDSFSVGISGDTKLGKNKNSNKIKMKLFESVKQFIREN-IETELELDKVA 362 Query: 366 KKNHVSPNYLSYLFKKNTGHNLWEYVIKLRMEDSREMLLHTDLRRYEIAERVGYESPEHF 425 +S Y S FK+ TG N EYV K R++ ++E+L ++ E+ +VGY P +F Sbjct: 363 SNFGLSVYYFSRTFKEVTGVNFSEYVNKCRIDVAKELLSTGEMNVKEVCYKVGYNDPNYF 422 Query: 426 SKIFKKYYGISPSELK 441 SK+FKKY G+SP+ K Sbjct: 423 SKVFKKYEGVSPANFK 438 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,626,794,904 Number of extensions: 111503569 Number of successful extensions: 370856 Number of sequences better than 1.0e-05: 5680 Number of HSP's gapped: 380485 Number of HSP's successfully gapped: 6287 Length of query: 442 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 303 Effective length of database: 1,751,175,118 Effective search space: 530606060754 Effective search space used: 530606060754 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)