BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0350.0021.p (234 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KK00.1 B3KK00_9BACI Cyclic nucleotide-binding 387 e-106 B1D6G5.1 B1D6G5_9BACL Transcriptional regulator, Crp/Fnr family 263 1e-68 C0ZKM2.1 C0ZKM2_BREBN Probable transcriptional regulator 179 2e-43 Q5L1V7.1 Q5L1V7_GEOKA Transcriptional regulator (FNR/CRP family) 173 1e-41 B3K3U4.1 B3K3U4_9BACI Cyclic nucleotide-binding 171 4e-41 >B3KK00.1 B3KK00_9BACI Cyclic nucleotide-binding Length = 241 Score = 387 bits (994), Expect = e-106, Method: Compositional matrix adjust. Identities = 182/224 (81%), Positives = 198/224 (88%), Gaps = 1/224 (0%) Query: 12 CFSEQNFNRLLVTMKERMVPEGSHLFWEGDYSDKLFYIKRGRVKLTKSTDEGKELILYMY 71 CFSEQN NRLLVTMKER++PEGSHLFWEGD++DKL+++K+GR+KLTKSTDEGKELILYMY Sbjct: 18 CFSEQNRNRLLVTMKERVLPEGSHLFWEGDFADKLYFVKQGRIKLTKSTDEGKELILYMY 77 Query: 72 QAGDMVGQADPFFSTKHSFTAXXXXXXXXXXXXQKDLEILICQHCDFAIDFMKWMGIHHR 131 GDMVGQADPFFS HSF+A KDLE+LICQHCDFAIDFMKWMGIHHR Sbjct: 78 HPGDMVGQADPFFSNNHSFSAEVLEDSVVGVIEHKDLELLICQHCDFAIDFMKWMGIHHR 137 Query: 132 LTQTKFRDLMMYGKPGALCSTLIRLGNTYGEKSGD-SILINKKITHTDLSNMIGATRESV 190 +TQTKFRDLMMYGKPGAL STLIRLGNTYG+ D +ILINKKITHTDLSNMIGATRESV Sbjct: 138 ITQTKFRDLMMYGKPGALTSTLIRLGNTYGQHQEDGTILINKKITHTDLSNMIGATRESV 197 Query: 191 NRMLSDLRKKDAVEYENGMIVIKDLSMLQDICHCELCPNEICRI 234 NRMLSDLRKKDA+EY GMIVIKDL MLQ+ICHCELCPNEICRI Sbjct: 198 NRMLSDLRKKDAIEYAGGMIVIKDLPMLQEICHCELCPNEICRI 241 >B1D6G5.1 B1D6G5_9BACL Transcriptional regulator, Crp/Fnr family Length = 236 Score = 263 bits (671), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 120/222 (54%), Positives = 164/222 (73%) Query: 13 FSEQNFNRLLVTMKERMVPEGSHLFWEGDYSDKLFYIKRGRVKLTKSTDEGKELILYMYQ 72 S+++F +L M +R +GS LFWEGD +DKL++I +GRV+ KSTD G+ L LY+YQ Sbjct: 15 LSKESFEKLDSIMYKRAYEKGSCLFWEGDAADKLYFIMKGRVRAVKSTDSGRTLTLYLYQ 74 Query: 73 AGDMVGQADPFFSTKHSFTAXXXXXXXXXXXXQKDLEILICQHCDFAIDFMKWMGIHHRL 132 GD++GQ DPF + HSF A +KDLE+L+ QH D A++FM+WMG+ HRL Sbjct: 75 KGDLIGQMDPFPDSVHSFRAEVTEDAKIGVIQRKDLEVLLWQHGDLAVEFMRWMGLMHRL 134 Query: 133 TQTKFRDLMMYGKPGALCSTLIRLGNTYGEKSGDSILINKKITHTDLSNMIGATRESVNR 192 TQTKFRDLMM+GK GALCS LIRL N+YG+ + + I I KI+++++++MIGATRESVNR Sbjct: 135 TQTKFRDLMMFGKTGALCSLLIRLSNSYGKPTAEHIFITLKISNSEMADMIGATRESVNR 194 Query: 193 MLSDLRKKDAVEYENGMIVIKDLSMLQDICHCELCPNEICRI 234 MLSDL+K D + YE+G ++IK+L L++ C CE CP EICR+ Sbjct: 195 MLSDLKKDDVIAYEDGHLIIKNLRYLRETCCCENCPKEICRM 236 >C0ZKM2.1 C0ZKM2_BREBN Probable transcriptional regulator Length = 235 Score = 179 bits (454), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 91/213 (42%), Positives = 147/213 (69%), Gaps = 3/213 (1%) Query: 24 TMKERMVPEGSHLFWEGDYSDKLFYIKRGRVKLTKSTDEGKELILYMYQAGDMVGQADPF 83 ++++ VP G+ LF +G+ +D+LF I G++KLTK+T++GKEL L ++ AG++VG + F Sbjct: 24 SVRKNFVP-GAVLFLDGERADQLFLISSGQIKLTKNTNDGKELTLQVFGAGELVGVSGLF 82 Query: 84 FST-KHSFTAXXXXXXXXXXXXQKDLEILICQHCDFAIDFMKWMGIHHRLTQTKFRDLMM 142 ++ T ++ LE ++ ++ F +DF++WMG+ +R Q+KFRDL++ Sbjct: 83 EQELTYTSTGTMLMEGEVWIIPRQGLEKMLIKNGQFCVDFLRWMGLMNRRMQSKFRDLLL 142 Query: 143 YGKPGALCSTLIRLGNTYGEKSGDSILINKKITHTDLSNMIGATRESVNRMLSDLRKKDA 202 GK GAL STLIR+ NTYG+ D ILI+ +T+ DL+ IG TRESVNRMLSDL+K+D+ Sbjct: 143 NGKIGALYSTLIRMSNTYGKPHPDGILIDLSLTNRDLAQFIGLTRESVNRMLSDLKKQDS 202 Query: 203 VE-YENGMIVIKDLSMLQDICHCELCPNEICRI 234 ++ +G I+IKDL+ L++ +C+ CP +IC++ Sbjct: 203 IDLLPHGHILIKDLAYLKEAIYCDDCPPDICQM 235 >Q5L1V7.1 Q5L1V7_GEOKA Transcriptional regulator (FNR/CRP family) Length = 228 Score = 173 bits (438), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 88/206 (42%), Positives = 129/206 (62%), Gaps = 1/206 (0%) Query: 30 VPEGSHLFWEGDYSDKLFYIKRGRVKLTKSTDEGKELILYMYQAGDMVGQADPFF-STKH 88 + +G++LF EG+ +D ++YI+ G+++++K +G+EL L + GD++G+ F ++ Sbjct: 22 LEKGTYLFQEGEKADDIYYIQSGKIQISKMDMDGRELALRICSEGDLIGELTLFCPGARY 81 Query: 89 SFTAXXXXXXXXXXXXQKDLEILICQHCDFAIDFMKWMGIHHRLTQTKFRDLMMYGKPGA 148 TA ++ LE + + AI+ MKWM +H R TQTKFRDL+++GK GA Sbjct: 82 MLTAKALEDSVVSAIPRERLEQELANNPTLAIELMKWMSLHFRKTQTKFRDLILHGKKGA 141 Query: 149 LCSTLIRLGNTYGEKSGDSILINKKITHTDLSNMIGATRESVNRMLSDLRKKDAVEYENG 208 L STLIRL N+YG D ILIN +T+ +L+N G RE VNRMLSDLRKK + E G Sbjct: 142 LYSTLIRLCNSYGVMKEDGILINVPLTNQELANFCGTAREVVNRMLSDLRKKGVISVEKG 201 Query: 209 MIVIKDLSMLQDICHCELCPNEICRI 234 I + +L L+D CE CP E+CRI Sbjct: 202 KICVHNLQYLRDEIACEGCPPELCRI 227 >B3K3U4.1 B3K3U4_9BACI Cyclic nucleotide-binding Length = 249 Score = 171 bits (434), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 83/205 (40%), Positives = 126/205 (61%), Gaps = 3/205 (1%) Query: 33 GSHLFWEGDYSDKLFYIKRGRVKLTKSTDEGKELILYMYQAGDMVGQADPFFSTKHSFTA 92 G L+ E D +D+L+++ RG +K++K + G L ++ GD+ G+ DPF H F A Sbjct: 45 GDCLYQENDPADRLYFVNRGSLKVSKLLEGGLSATLSLHIPGDLFGEPDPFGRAVHHFEA 104 Query: 93 XXXXXXXXXXXXQKDLEILICQHCDFAIDFMKWMGIHHRLTQTKFRDLMMYGKPGALCST 152 Q +L+ +I + DFA+++M WM + R TQ+K RDL+++GK GALCS Sbjct: 105 RAMEDSEVGVVPQTELDKIIRINGDFAVEYMGWMALMQRTTQSKLRDLLLHGKSGALCSL 164 Query: 153 LIRLGNTY---GEKSGDSILINKKITHTDLSNMIGATRESVNRMLSDLRKKDAVEYENGM 209 L+RL N Y G +I K+IT+ +++ MIG+TRESVNR+L++L+ + E G Sbjct: 165 LLRLYNMYGTCGTAKDHRAIIGKRITNLEMAEMIGSTRESVNRILNELKDLGVISTERGR 224 Query: 210 IVIKDLSMLQDICHCELCPNEICRI 234 IV+ D L++ICHCE CP EICR+ Sbjct: 225 IVLNDPGYLRNICHCEDCPKEICRM 249 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.323 0.138 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,249,354,680 Number of extensions: 44896571 Number of successful extensions: 105620 Number of sequences better than 1.0e-05: 971 Number of HSP's gapped: 105255 Number of HSP's successfully gapped: 971 Length of query: 234 Length of database: 3,060,696,203 Length adjustment: 131 Effective length of query: 103 Effective length of database: 1,826,543,238 Effective search space: 188133953514 Effective search space used: 188133953514 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 129 (54.3 bits)